CECAD

Recent selected Publications
  • Finger F, Ottens F,Springhorn A, Drexel T, Proksch L, Metz S, Cochella L, Hoppe T (2019). Olfaction regulates organismal proteostasis and longevity via miRNA-dependent signaling. Nat. Metab. DOI: https://doi.org/10.1038/s42255-019-0033-z
  • Sprenger HS, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2019). Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 2019 Jan;11(1). pii: e9288. DOI: 10.15252/emmm.201809288 
  • Persa OD, Niessen CM. Epithelial polarity limits EMT. Nat Cell Biol. 2019 Mar;21(3):299-300. DOI: 10.1038/s41556-019-0284-7.
  • Koyuncu S, Saez I, Lee HJ, Gutierrez-Garcia R, Pokrzywa W, Fatima A, Hoppe T, Vilchez D (2018). The ubiquitin ligase UBR5 suppresses proteostasis collapse in immortal pluripotent stem cells from Huntington’s disease patients. Nature Communications  9: 2886. DOI: 10.1038/s41467-018-05320-3

In a society where people are living longer and longer the Cologne Cluster of Excellence CECAD at the University of Cologne explores the causes of aging processes and aging-associated disorders.