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Schwartz S, Cornely OA, Hamed K, Marty FM, Maertens J, Rahav G, Herbrecht R, Heinz WJ (2020). Isavuconazole for the treatment of patients with invasive fungal diseases involving the central nervous system. Med Mycol. 2020 Jun 1;58(4):417-424. doi: 10.1093/mmy/myz103. PMID: 31613363
Koehler P, Denis B, Denning DW, Gangneux JP, Hoenigl M, Kontoyiannis DP, Krause R, Lagrou K, Lass-Flörl C, Maertens J, Mareković I, Meis JF, Molina JM, Pleško S, Prattes J, Rath PM, Rautemaa-Richardson R, Richardson M, Segal E, Seidel D, Spriet I, Steinmann J, Verweij PE, Cornely OA; European Confederation of Medical Mycology (ECMM) (2020). European confederation of medical mycology expert consult-An ECMM excellence center initiative. Mycoses. 2020 Jun;63(6):566-572. doi: 10.1111/myc.13076. Epub 2020 Apr 13. PMID: 32181546
Jenks JD, Seidel D, Cornely OA, Chen S, van Hal S, Kauffman C, Miceli MH, Heinemann M, Christner M, Jover Sáenz A, Burchardt A, Kemmerling B, Herbrecht R, Steinmann J, Shoham S, Gräber S, Pagano L, Deeren D, Aslam S, Taplitz R, Revankar SG, Baddley J, Mehta SR, Reed S, Slavin MA, Hoenigl M (2020). Voriconazole plus terbinafine combination antifungal therapy for invasive Lomentospora prolificans infections: analysis of 41 patients from the FungiScope® registry 2008-2019. Clin Microbiol Infect. 2020 Jun;26(6):784.e1-784.e5. doi: 10.1016/j.cmi.2020.01.012. Epub 2020 Jan 20. PMID: 31972317
Verweij PE, Gangneux JP, Bassetti M, Brüggemann RJM, Cornely OA, Koehler P, Lass-Flörl C, van de Veerdonk FL, Chakrabarti A, Hoenigl M (2020). Diagnosing COVID-19-associated pulmonary aspergillosis. Lancet Microbe. 2020 Jun; 1(2): e53–e55. Published online 2020 May 10. doi: 10.1016/S2666-5247(20)30027-6
Thompson Iii GR, Cornely OA, Pappas PG, Patterson TF, Hoenigl M, Jenks JD, Clancy CJ, Nguyen MH (2020). Invasive Aspergillosis as an Under-recognized Superinfection in COVID-19. Open Forum Infect Dis. 2020 Jun 19;7(7):ofaa242. doi:10.1093/ofid/ofaa242. eCollection 2020 Jul
Stemler J, Koehler P, Maurer C, Müller C, Cornely OA (2020). Antifungal prophylaxis and novel drugs in acute myeloid leukemia: the midostaurin and posaconazole dilemma. Ann Hematol. 2020 Jul;99(7):1429-1440. doi: 10.1007/s00277-020-04107-1. Epub 2020 Jun 8
Stemler J, Hamed K, Salmanton-García J, Rezaei-Matehkolaei A, Gräfe SK, Sal E, Zarrouk M, Seidel D, Abdelaziz Khedr R, Ben-Ami R, Ben-Chetrit E, Roth Y, Cornely OA (2020). Mucormycosis in the Middle East and North Africa: Analysis of the FungiScope® registry and cases from the literature. Mycoses. 2020 Oct;63(10):1060-1068. doi: 10.1111/myc.13123. Epub 2020 Aug 29
Stemler J, Bruns C, Mellinghoff SC, Alakel N, Akan H, Ananda-Rajah M, Auberger J, Bojko P, Chandrasekar PH, Chayakulkeeree M, Cozzi JA, de Kort EA, Groll AH, Heath CH, Henze L, Hernandez Jimenez M, Kanj SS, Khanna N, Koldehoff M, Lee DG, Mager A, Marchesi F, Martino-Bufarull R, Nucci M, Oksi J, Pagano L, Phillips B, Prattes J, Pyrpasopoulou A, Rabitsch W, Schalk E, Schmidt-Hieber M, Sidharthan N, Soler-Palacín P, Stern A, Weinbergerová B, El Zakhem A, Cornely OA, Koehler P (2020). Baseline Chest Computed Tomography as Standard of Care in High-Risk Hematology Patients. J Fungi (Basel). 2020 Mar; 6(1): 36. Published online 2020 Mar 13. doi: 10.3390/jof6010036
Seidel D, Hassler A, Salmanton-García J, Koehler P, Mellinghoff SC, Carlesse F, Cheng MP, Falces-Romero I, Herbrecht R, Jover Sáenz A, Klimko N, Mareş M, Lass-Flörl C, Soler-Palacín P, Wisplinghoff H, Cornely OA, Pana Z, Lehrnbecher T (2020). Invasive Scedosporium spp. and Lomentospora prolificans infections in pediatric patients: Analysis of 55 cases from FungiScope® and the literature. Int J Infect Dis. 2020 Mar;92:114-122. doi: 10.1016/j.ijid.2019.12.017. Epub 2019 Dec 19
Schwartz S, Cornely OA, Hamed K, Marty FM, Maertens J, Rahav G, Herbrecht R, Heinz WJ (2020). Isavuconazole for the treatment of patients with invasive fungal diseases involving the central nervous system. Med Mycol. 2020 Jun 1;58(4):417-424. doi: 10.1093/mmy/myz103
Schommers P, Gruell H, Abernathy ME, Tran MK, Dingens AS, Gristick HB, Barnes CO, Schoofs T, Schlotz M, Vanshylla K, Kreer C, Weiland D, Holtick U, Scheid C, Valter MM, van Gils MJ, Sanders RW, Vehreschild JJ, Cornely OA, Lehmann C, Fätkenheuer G, Seaman MS, Bloom JD, Bjorkman PJ, Klein F (2020). Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell. 2020 Feb 6;180(3):471-489.e22. doi: 10.1016/j.cell.2020.01.010. Epub 2020 Jan 30
Salmanton-García J, Koehler P, Kindo A, Falces-Romero I, García-Rodríguez J, Ráčil Z, Chen SC, Klimko N, Desoubeaux G, Thompson Gr, III, Benítez-Peñuela M, Rodríguez JY, Sheppard DC, Hoenigl M, Le Govic Y, Badali H, Baddley JW, Chander J, Ingram PR, Pakstis DL, Mellinghoff SC, Atıcı S, Cesaro S, Chakrabarti A, Dupont D, González GM, Hatvani L, Herbrecht R, Klyasova G, Lass-Flörl C, Mareș M, Mullane K, Vinh DC, Wisplinghoff H, Lackner M, Cornely OA, Seidel D (2020). Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope(Ⓡ)-Global Registry for Emerging Fungal Infections. J Infect. 2020 Nov;81(5):802-815. doi: 10.1016/j.jinf.2020.08.015. Epub 2020 Aug 13
Laursen CB, Davidsen JR, Van Acker L, Salzer HJF, Seidel D, Cornely OA, Hoenigl M, Alastruey- Izquierdo A, Hennequin C, Godet C, Barac A, Flick H, Munteanu O, Van Braeckel E (2020). CPAnet Registry-An International Chronic Pulmonary Aspergillosis Registry. J Fungi (Basel). 2020 Jun 29;6(3):96. doi: 10.3390/jof6030096
Koehler P, Denis B, Denning DW, Gangneux JP, Hoenigl M, Kontoyiannis DP, Krause R, Lagrou K, Lass-Flörl C, Maertens J, Mareković I, Meis JF, Molina JM, Pleško S, Prattes J, Rath PM, Rautemaa-Richardson R, Richardson M, Segal E, Seidel D, Spriet I, Steinmann J, Verweij PE, Cornely OA (2020). European confederation of medical mycology expert consult-An ECMM excellence center initiative. Mycoses. 2020 Jun;63(6):566-572. doi: 10.1111/myc.13076. Epub 2020 Apr 13
Koehler P, Cornely OA, Böttiger BW, Dusse F, Eichenauer DA, Fuchs F, Hallek M, Jung N, Klein F, Persigehl T, Rybniker J, Kochanek M, Böll B, Shimabukuro-Vornhagen A (2020). COVID-19 associated pulmonary aspergillosis. Mycoses. 2020 Jun;63(6):528-534. doi: 10.1111/myc.13096. Epub 2020 May 15
Jakob CEM, Stecher M, Classen AY, Hamprecht A, Cornely OA, Vehreschild JJ (2020). Association Between Prescribed Opioids and Infections in Patients Neutropenia and Cancer. JAMA Intern Med. 2019 Nov 4. doi: 10.1001/jamainternmed.2019.4714. [Epub ahead of print]
Hanssen R, Kohlenbach L, Albus K, Edwin Thanarajah S, Cornely OA, Tittgemeyer M, Faust M (2020). Erfolgreiche Lebensstiländerung für schwer adipöse Patienten - Eine kontrollierte Studie zur Evaluation eines Patientenschulungsprogramms. Diabetologie und Stoffwechsel 2020; 15(02): 157-64
Guery B, Georgopali A, Karas A, Kazeem G, Michon I, Wilcox MH, Cornely OA (2020). Pharmacokinetic analysis of an extended-pulsed fidaxomicin regimen for the treatment of Clostridioides (Clostridium) difficile infection in patients aged 60 years and older in the EXTEND randomized controlled trial. J Antimicrob Chemother. 2020 Apr 1;75(4):1014-1018. doi: 10.1093/jac/dkz549
Fürstenau M, Simon F, Cornely OA, Hicketier T, Eichhorst B, Hallek M, Mellinghoff SC (2020). Invasive Aspergillosis in Patients Treated With Ibrutinib. Hemasphere. 2020 Apr; 4(2): e309. Published online 2020 Feb 13. doi: 10.1097/HS9.0000000000000309
Davies K, Lawrence J, Berry C, Davis G, Yu H, Cai B, Gonzalez E, Prantner I, Kurcz A, Macovei I, Pituch H, Nováková E, Nyč O, Gärtner B, Berger FK, Oleastro M, Cornely OA, Vehreschild M, Pedneault L, Wilcox M (2020). Risk Factors for Primary Clostridium difficile Infection; Results From the Observational Study of Risk Factors for Clostridium difficile Infection in Hospitalized Patients With Infective Diarrhea (ORCHID). Front Public Health. 2020 Jul 17;8:293. doi: 10.3389/fpubh.2020.00293. eCollection 2020
Cornely OA, Mullane KM, Birch T, Hazan-Steinberg S, Nathan R, Bouza E, Calfee DP, Ellison MC, Wong MT, Dorr MB (2020). Exploratory Evaluation of Bezlotoxumab on Outcomes Associated With Clostridioides difficile Infection in MODIFY I/II Participants With Cancer. Open Forum Infect Dis. 2020 Feb; 7(2): ofaa038. Published online 2020 Jan 31. doi: 10.1093/ofid/ofaa038
Cornely OA, Cisneros JM, Torre-Cisneros J, Rodríguez-Hernández MJ, Tallón-Aguilar L, Calbo E, Horcajada JP, Queckenberg C, Zettelmeyer U, Arenz D, Rosso-Fernández CM, Jiménez-Jorge S, Turner G, Raber S, O'Brien S, Luckey A (2020). Pharmacokinetics and safety of aztreonam/avibactam for the treatment of complicated intra-abdominal infections in hospitalized adults: results from the REJUVENATE study. J Antimicrob Chemother. 2020 Mar 1;75(3):618-627. doi: 10.1093/jac/dkz497
Bouza E, Cornely OA, Ramos-Martinez A, Plesniak R, Ellison MC, Hanson ME, Dorr MB (2020). Analysis of C. difficile infection-related outcomes in European participants in the bezlotoxumab MODIFY I and II trials. Eur J Clin Microbiol Infect Dis. 2020 Oct;39(10):1933-1939. doi: 10.1007/s10096-020-03935-3. Epub 2020 Jun 6
Augustin M, Schommers P, Suárez I, Koehler P, Gruell H, Klein F, Maurer C, Langerbeins P, Priesner V, Schmidt-Hellerau K, Malin JJ, Stecher M, Jung N, Wiesmüller G, Meissner A, Zweigner J, Langebartels G, Kolibay F, Suárez V, Burst V, Valentin P, Schedler D, Cornely OA, Hallek M, Fätkenheuer G, Rybniker J, Lehmann C (2020). Rapid response infrastructure for pandemic preparedness in a tertiary care hospital: lessons learned from the COVID-19 outbreak in Cologne, Germany, February to March 2020. Euro Surveill. 2020 May 28; 25(21): 2000531. doi: 10.2807/1560-7917.ES.2020.25.21.2000531
Arastehfar A, Carvalho A, van de Veerdonk FL, Jenks JD, Koehler P, Krause R, Cornely OA, D SP, Lass-Flörl C, Hoenigl M (2020). COVID-19 Associated Pulmonary Aspergillosis (CAPA)-From Immunology to Treatment. J Fungi (Basel). 2020 Jun; 6(2): 91.Published online 2020 Jun 24. doi: 10.3390/jof6020091
Koehler P, Adam M, Cornely OA (2020). Aspergillus endocarditis. MSG ERC Doctor Fungus, 2020 Feb 2020
Johnson MD, Lewis RE, Dodds Ashley ES, Ostrosky-Zeichner L, Zaoutis T, Thompson GR, Andes DR, Walsh TJ, Pappas PG, Cornely OA, Perfect JR, Kontoyiannis DP (2020). Core Recommendations for Antifungal Stewardship: A Statement of the Mycoses Study Group Education and Research Consortium. J Infect Dis. 2020 Aug 5;222(Supplement_3):S175-S198. doi: 10.1093/infdis/jiaa394
Jenks JD, Cornely OA, Chen SC, Thompson GR, 3rd, Hoenigl M (2020). Breakthrough invasive fungal infections: Who is at risk? Mycoses. 2020 Oct;63(10):1021-1032. doi: 10.1111/myc.13148. Epub 2020 Sep 4
Chakrabarti A, Meis JF, Cornely OA (2020). International Society for Human and Animal Mycology (ISHAM)-New Initiatives. J Fungi (Basel). 2020 Jun 30;6(3):97. doi: 10.3390/jof6030097
von Lilienfeld-Toal M, Vehreschild JJ, Cornely O, Pagano L, Compagno F, Hirsch HH (2020). Frequently asked questions regarding SARS-CoV-2 in cancer patients-recommendations for clinicians caring for patients with malignant diseases. Leukemia. 2020 Jun;34(6):1487-1494. doi: 10.1038/s41375-020-0832-y. Epub 2020 May 1.
Ruhnke M, Cornely OA, Schmidt-Hieber M, Alakel N, Boell B, Buchheidt D, Christopeit M, Hasenkamp J, Heinz WJ, Hentrich M, Karthaus M, Koldehoff M, Maschmeyer G, Panse J, Penack O, Schleicher J, Teschner D, Ullmann AJ, Vehreschild M, von Lilienfeld-Toal M, Weissinger F, Schwartz S (2020). Treatment of invasive fungal diseases in cancer patients-Revised 2019 Recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Mycoses. 2020 Jul;63(7):653-682. doi: 10.1111/myc.13082. Epub 2020 May 12
Timmers PRHJ, Wilson JF, Joshi PK, Deelen J (2020). Multivariate genomic scan implicates novel loci and haem metabolism in human ageing. Nat Commun. 2020 Jul 16;11(1):3570. doi: 10.1038/s41467-020-17312-3
Deelen J (2020). Searching for the genetic key to a long and healthy life. Elife. 2020 Apr 24;9:e57242. doi: 10.7554/eLife.57242
Pisanti S, Deelen J, Gallina AM, Caputo M, Citro M, Abate M, Sacchi N, Vecchione C, Martinelli R (2020). Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19. J Transl Med. 2020 Sep 15;18(1):352. doi: 10.1186/s12967-020-02515-5
Beekman M, Schutte BAM, van den Akker EB, Noordam R, Dibbets-Schneider P, de Geus-Oei L, Deelen J, van de Rest O, van Heemst D, Feskens EJM, Slagboom E (2020). Lifestyle-Intervention-Induced Reduction of Abdominal Fat Is Reflected by a Decreased Circulating Glycerol Level and an Increased HDL Diameter. Mol Nutr Food Res. 2020 May;64(10):e1900818. doi: 10.1002/mnfr.201900818. Epub 2020 Apr 23
Cohen AA, Kennedy BK, Anglas U, Bronikowski AM, Deelen J, Dufour F, Ferbeyre G, Ferrucci L, Franceschi C, Frasca D, Fruguet B, Gaudreau P, Gladyshev VN, Gonos ES, Gorbunova V, Gut P, Ivanchenko M, Legault V, Lemaitre JF, Liontis T, Liu GH, Liu M, Maier AB, Nobrega OT, Rikkert MGMO, Pawelec G, Rheault S, Senior AM, Simm A, Soo S, Traa A, Ukraintseva S, Vanhaelen Q, van Raamdonk JM, Witkowski JM, Yashin AI, Ziman R, Fülöp T (2020). Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework. Mech Ageing Dev. 2020 Oct;191:111316. doi: 10.1016/j.mad.2020.111316. Epub 2020 Jul 18
Gutman D, Lidzbarsky G, Milman S, Gao T, Sin-Chan P, Gonzaga-Jauregui C, Regeneron Genetic Center, Deelen J, Shuldiner AR, Barzilai N, Atzmon G (2020). Similar burden of pathogenic coding variants in exceptionally long-lived individuals and individuals without exceptional longevity. Aging Cell. 2020 Oct;19(10):e13216. doi: 10.1111/acel.13216. Epub 2020 Aug 29
Klarić L, Tsepilov YA, Stanton CM, Mangino M, Sikka TT, Esko T, Pakhomoy E, Salo P, Deelen J, McGurnaghan SJ, Keser T, Vuckovic F, Ugrina I, Kristic J, Gudeli I, Stambuk J, Plomp R, Pucic-Bakovic M, Pavic T, Vilai M, Trbojevic-Akmacic I, Drake C, Dobrinic P, Mlinarec J, Jelusic B, Richmond A, Timofeeva M, Grishchenko AK, Dmitrieva J, Bermingham ML, Sharapov SZ, Farrington SM, Theodoratou E, Uh HW, Beekman M, Slagboom EP, Louis E, Georges M, Wuhrer M, Colhoun HM, Dunlop MG, Perola M, Fischer K, Polasek O, Campbell H, Rudan I, Wilson JF, Zoldos V, Vitart V, Spector T, Auchenko YS, Lauc G, Hayward C (2020). Glycosylation of Immunoglobulin G Is Regulated by a Large Network of Genes Pleiotropic With Inflammatory Diseases. Sci Adv. 2020 Feb 19;6(8):eaax0301. doi: 10.1126/sciadv.aax0301. eCollection 2020 Feb
Li C, Stoma S, Lotta LA, Warner S, Albrecht E, Allione A, Arp PP, Broer L, Buxton JL, Da Salva Couto Alves A, Deelen J, Fedko IO, Gordon SD, Jiang T, Karlsson R, Kerrison N, Loe TK, Mangino M, Milaneschi Y, Miraglio B, Perviakova N, Russo A, Surakka I, van der Spek A, Verhoeven IE, Amin N, Beekman M, Blakemore AI, Canzian F, Hamby SE, Hottenga JJ, Jones PD, Jousilahti P, Mägi R, Medland SE, Montgomery GW, Nyholt DR, Perola M, Pietiläinen KH, Salomaa V, Sillanpää E, Suchiman HE, van Heemst D, Willemsen G, Agudo A, Boeing H, Boomsma DI, CHirlaque MD, Fagherazzi G, Ferrari P, Franks P, Gieger C, Eriksson JG, Gunter M, Hägg S, Hovatta J, Imaz L, Kaprio J, Kaaks R, Key T, Krogh V, Martin NG, Melander O, Metspalu A, Moreno C, Onland-Moret NC, Nilsson P, Ong KK, Overvad K, Palli D, Panico S, Pedersen NL, Penninx BWJH, Quiros JR, Jarvelin MR, Rodriguez-Barranco M, Scott RA, Severi G, Slagboom PE, Spector TD, Tionneland A, Trichopoulou A, Tumino R, Uitterlinden AG, van der Schouw YT, van Dujin CM, Weiderpass E, Denchi EL, Matullo G, Butterworth AS, Danesh J, Samani NJ, Wareham NJ, Nelson CP, Langenberg C, Codd V (2020). Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. Am J Hum Genet. 2020 Mar 5;106(3):389-404. doi: 10.1016/j.ajhg.2020.02.006. Epub 2020 Feb 27
Van den Akker EB, Trompet S, Wolf JJHB, Beekman M, Suchiman HED, Deelen J, Asselbergs FW, Boersma E, Cats D, Elders PM, Gelejnse JM, Ikram MA, Kloppenburg M, Mei H, Meulenbelt I, Mooijaart SP, Nelissen RGHH, Netea MG, Penninx BWJH, Slofstra M, Stehouwer CDA, Swertz MA, Teunissen CE, Terwindt GM, Hart LM, van den Maagdenberg AMJM, van der Harst P, van der Horst ICC, van der Kallen CJH, van Greevenbroek MMJ, van Spil WE, Wijmenga C, Zhernakova A, Zwinderman AH, Sattar N, Jukema JW, van Dujin CM, Boomsma DI, Reinders MJT, Slagboom E (2020). Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease. Circ Genom Precis Med. 2020 Oct;13(5):541-547. doi: 10.1161/CIRCGEN.119.002610. Epub 2020 Aug 14
Martin Denzel
Sawarkar R, Scherz-Shouval R, Denzel MS, Saarikangas J (2020). Chaperoning junior faculty: Institutional support and guidance can relieve challenges for early-career group leaders and improve academic performance. EMBO Rep. 2019 Jan;20(1). pii: e47163. doi: 10.15252/embr.201847163. Epub 2018 Nov 23
Horn M, Denzel SI, Srinivasan B, Allmeroth K, Schiffer I, Karthikaisamy V, Miethe S, Breuer P, Antebi A, Denzel MS (2020). Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response. iScience. 2020 Mar 27; 23(3): 100887. Published online 2020 Feb 5. doi: 10.1016/j.isci.2020.100887
Ruegenberg S, Horn M, Pichlo C, Allmeroth K, Baumann U, Denzel MS (2020). Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun. 2020 Feb 4;11(1):687. doi: 10.1038/s41467-020-14524-5
Allmeroth K, Horn M, Kroef V, Miethe S, Müller RU, Denzel MS (2020). Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma. Leukemia. doi.org/10.1038/s41375-020-0989-4
Kim CS, Ding X, Allmeroth K, Biggs LC, Kolenc OI, L’Hoest N, Chacón-Martínez CA, Edlich-Muth C, Giavalisco P,Quinn KP, Denzel MS, Eming SA, Wickström SA (2020). Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle. Cell Metab. 2020 Oct 6;32(4):629-642.e8. doi: 10.1016/j.cmet.2020.08.011. Epub 2020 Sep 8
Bonekamp NA, Peter B, Hillen HS, Felser A, Bergbrede T, Choidas A, Horn M, Unger A, Di Lucrezia R, Atanassov I, Li X, Koch U, Menninger S, Boros J, Habenberger P, Giavalisco P, Cramer P, Denzel MS, Nussbaumer P, Klebl B, Falkenberg M, Gustafsson CM, Larsson NG (2020). Small-molecule inhibitors of human mitochondrial DNA transcription. Nature. 2020 Dec;588(7839):712-716. doi: 10.1038/s41586-020-03048-z. Epub 2020 Dec 16
Alexander Dilthey
Walker A, Houwaart T, Wienemann T, Vasconcelos MK, Strelow D, Senff T, Hulse L, Adams O, Andree M, Hauka S, Feldt T, Jensen BE, Keitel V, Kindgen-Milles D, Timm J, Pfeffer K, Dilthey AT (2020). Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020. Euro Surveill. 2020 Jun 4; 25(22): 2000746
Dilthey AT, Meyer SA, Kaasch AJ (2020). Ultraplexing: increasing the efficiency of long-read sequencing for hybrid assembly with k-mer-based multiplexing. Genome Biol. 2020; 21: 68
Dilthey AT (2020). State-of-the-art genome inference in the human MHC. Int J Biochem Cell Biol. 2020 Nov 12:105882. doi: 10.1016/j.biocel.2020.105882. Online ahead of print. PMID: 33189874
Henrich B, Hammerlage S, Scharf S, Haberhausen D, Fürnkranz U, Köhrer K, Peitzmann L, Fiori PL, Spergser J, Pfeffer K, Dilthey AT (2020). Characterisation of mobile genetic elements in Mycoplasma hominis with the description of ICEHo-II, a variant mycoplasma integrative and conjugative element. Mob DNA. 2020 Nov 7;11(1):30. doi: 10.1186/s13100-020-00225-9. PMID: 33292499
Chin CS, Wagner J, Zeng Q, Garrison E, Garg S, Fungtammasan A, Rautiainen M, Aganezov S, Kirsche M, Zarate S, Schatz MC, Xiao C, Rowell WJ, Markello C, Farek J, Sedlazeck FJ, Bansal V, Yoo B, Miller N, Zhou X, Carroll A, Barrio AM, Salit M, Marschall T, Dilthey AT, Zook JM (2020). A diploid assembly-based benchmark for variants in the major histocompatibility complex. Nat Commun. 2020 Sep 22;11(1):4794. doi: 10.1038/s41467-020-18564-9. PMID: 32963235; PMCID: PMC7508831.
Ramani A, Müller L, Ostermann PN, Gabriel E, Abida-Islam P, Müller-Schiffmann A, Mariappan A, Goureau O, Gruell H, Walker A, Andrée M, Hauka S, Houwaart T, Dilthey AT, Wohlgemuth K, Omran H, Klein F, Wieczorek D, Adams O, Timm J, Korth C, Schaal H, Gopalakrishnan J (2020). SARS-CoV-2 targets neurons of 3D human brain organoids. EMBO J. 2020 Oct 15;39(20):e106230. doi: 10.15252/embj.2020106230. Epub 2020 Sep 23. PMID: 32876341; PMCID: PMC7560208.
Gleadall NS, Veldhuisen B, Gollub J, Butterworth AS, Ord J, Penkett CJ, Timmer TC, Sauer CM, van der Bolt N, Brown C, Brugger K, Dilthey AT, Duarte D, Grimsley S, van den Hurk K, Jongerius JM, Luken J, Megy K, Miflin G, Nelson CS, Prinsze FJ, Sambrook J, Simeoni I, Sweeting M, Thornton N, Trompeter S, Tuna S, Varma R, Walker MR; NIHR BioResource, Danesh J, Roberts DJ, Ouwehand WH, Stirrups KE, Rendon A, Westhoff CM, Di Angelantonio E, van der Schoot CE, Astle WJ, Watkins NA, Lane WJ. Development and validation of a universal blood donor genotyping platform: a multinational prospective study. Blood Adv. 2020 Aug 11;4(15):3495-3506. doi: 10.1182/bloodadvances.2020001894. PMID: 32750130; PMCID: PMC7422129.
Sallah N, Miley W, Labo N, Carstensen T, Fatumo S, Gurdasani D, Pollard MO, Dilthey AT, Mentzer AJ, Marshall V, Cornejo Castro EM, Pomilla C, Young EH, Asiki G, Hibberd ML, Sandhu M, Kellam P, Newton R, Whitby D, Barroso I. Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections. Nat Commun. 2020 Jul 31;11(1):3849. doi: 10.1038/s41467-020-17696-2. PMID: 32737300; PMCID: PMC7395761.
Kakanj P, Eming SA, Partridge L, Leptin M (2020). Long-term in vivo imaging of Drosophila larvae. Nat Protoc. 2020 Feb 10. doi: 10.1038/s41596-019-0282-z. [Epub ahead of print]
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Ding X, Willenborg, S, Bloch W, Wickström S, Wagle P, Brodesser S, Roers A, Jais A, Brüning JC, Hall MN, Rüegg M, Eming SA (2020). Epidermal mTORC2 controls lipid synthesis and filaggrin processing in epidermal barrier formation. J Allergy Clin Immunol. 2020 Jan;145(1):283-300.e8. doi: 10.1016/j.jaci.2019.07.033
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Mafalda Escobar-Henriques
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Martin Graef
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Grossek A, Oberste M, Bloch W, Wolf F, Hallek M, Elter T, Zimmer P (2020). Evaluating the Suitability of a Graded Exercise Test in Patients with Acute Leukemia or Lymphoma: 1240 Board #366 May 27 2:30 PM – 4:00 PM. Medicine & Science in Sports & Exercise. 52. 332-332. 10.1249/01.mss.0000677240.65044.d7.
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Jakobs F, Drost RMWA, Kron A, Heinen J, Hallek M, Reinhardt HC, Zander T, Kron F (2020). Economic Impact of the Introduction of Outpatient Medical Specialist Care (ASV) of Gastrointestinal Cancer Patients from a German Hospital Management Perspective. Oncol Res Treat. 2020;43(10):498-505. doi: 10.1159/000509618. Epub 2020 Sep 21. PMID: 32957103.
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Knuever J, Weiss J, Persa OD, Kreuzer K, Mauch C, Hallek M, Schlaak M (2020). The use of circulating cell-free tumor DNA in routine diagnostics of metastatic melanoma patients. Sci Rep. 2020 Mar 18;10(1):4940. doi: 10.1038/s41598-020-61818-1. PMID: 32188904; PMCID: PMC7080785.
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Kohlhas V, Hallek M, Nguyen PH (2020). Constitutive activation of Lyn kinase enhances BCR responsiveness, but not the development of CLL in Eµ-TCL1 mice. Blood Adv. 2020 Dec 22;4(24):6106-6116. doi: 10.1182/bloodadvances.2020002584. PMID: 33351104; PMCID: PMC7756995.
Krause G, Hassenrück F, Hallek M (2020). Cell line-based assessment of BTK inhibitors. Br J Pharmacol. 2020 May;177(9):2163-2165. doi: 10.1111/bph.14948. Epub 2020 Jan 28. PMID: 31994176; PMCID: PMC7161538.
Krause G, Hassenrück F, Hallek M (2020). Relevant Cytokines in the B Cell Lymphoma Micro-Environment. Cancers (Basel). 2020 Sep 5;12(9):2525. doi: 10.3390/cancers12092525. PMID: 32899476; PMCID: PMC7564074.
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Stilgenbauer S, Morschhauser F, Wendtner CM, Cartron G, Hallek M, Eichhorst B, Kozloff MF, Giever T, Lozanski G, Jiang Y, Huang H, Pignataro DS, Schary W, Humphrey K, Mobasher M, Salles G (2020). Venetoclax plus bendamustine-rituximab or bendamustine-obinutuzumab in chronic lymphocytic leukemia: final results of a phase 1b study (GO28440). Haematologica. 2020 Oct 29; Online ahead of print. doi: 10.3324/haematol.2020.261107. PMID: 33121235
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Herzog LK, Kevei É, Marchante R, Böttcher C, Bindesbøll C, Lystad AH, Pfeiffer A, Gierisch ME, Salomons FA, Simonsen A, Hoppe T, Dantuma NP (2020). The Machado-Joseph disease deubiquitylase ataxin-3 interacts with LC3C/GABARAP and promotes autophagy.Aging Cell e13051
Fatima A, Irmak D, Noormohammadi A, Rinschen MM, Das A, Leidecker O, Schindler C, Sánchez-Gaya V, Wagle P, Pokrzywa W, Hoppe T, Rada-Iglesias A, Vilchez D (2020). The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells. Commun Biol. 3: 262
Ravanelli S, den Brave F, and Hoppe T (2020). Mitochondrial quality control governed by ubiquitin. Front Cell Dev Biol.8: 270
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Bayer EA, Stecky RC, Neal L, Katsamba PS, Ahlsen G, Balaji V, Hoppe T, Shapiro L, Oren-Suissa M, Hobert O (2020). Ubiquitin-dependent regulation of a conserved DMRT protein controls sexually dimorphic synaptic connectivity and behavior. Elife. 2020 Oct 6;9:e59614. doi: 10.7554/eLife.59614. PMID: 33021200
Dantuma NP, Hoppe T, Herzog LK (2020). The price of longevity. Aging (Albany NY). 2020 Nov 28. doi: 10.18632/aging.104215. PMID: 33253121
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Pitter Huesgen
Hofsetz E, Demir F, Szczepanowska K, Kukat A, Kizhakkedathu JN, Trifunovic A, Huesgen PF (2020). The Mouse Heart Mitochondria N Terminome Provides Insights into ClpXP-Mediated Proteolysis. Mol Cell Proteomics. 2020 Aug;19(8):1330-1345. doi: 10.1074/mcp.RA120.002082. Epub 2020 Nov 23. PMID: 33451507
Dall E, Zauner FB, Soh WT, Demir F, Dahms SO, Cabrele C, Huesgen PF, Brandstetter H (2020). Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition. J Biol Chem. 2020 Sep 11;295(37):13047-13064. doi: 10.1074/jbc.RA120.014478. Epub 2020 Jul 21. PMID: 32719006
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Li M, Knapp SK, Iden S (2020). Mechanisms of melanocyte polarity and differentiation: What can we learn from other neuroectoderm-derived lineages? Curr Opin Cell Biol. 2020; 67:99-108. Published online 2020 Oct 21. doi: 10.1016/j.ceb.2020.09.001
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Frank Jessen
Wang X, Huang W, Su L, Xing Y, Jessen F, Sun Y, Shu N, Han Y (2020). Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease. Mol Neurodegener. 2020 Sep 22;15(1):55. doi: 10.1186/s13024-020-00395-3. PMID: 32962744 Review
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Günther SD, Fritsch M, Seeger JM, Schiffmann LM, Snipas SJ, Coutelle M, Kufer TA, Higgins PG, Hornung V, Bernardini ML, Höning S, Krönke M, Salvesen GS, Kashkar H (2020). Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide. Nat Microbiol. 2020 Feb;5(2):354-367. doi: 10.1038/s41564-019-0620-5 . Epub 2019 Dec 23
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Lampl S, Janas MK, Donakonda S, Brugger M, Lohr K, Schneider A, Manske K, Sperl LE, Wettmarshausen J, Müller C, Laschinger M, Hartmann D, Hüser N, Perrochi F, Schmidt-Kopplin P, Hagn F, Zender L, Hornung V, Borner C, Pichlmair A, Kashkar H, Klingenspor M, Prinz M, Schreiner S, Conrad M, Jost PJ, Zischka H, Steiger K, Krönke M, Zehn D, Protzer U, Heikenwälder M, Knolle PA, Wohlleber D (2020). Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNFR signaling in virus-infected hepatocytes. J Hepatol. 2020 Dec;73(6):1347-1359. doi: 10.1016/j.jhep.2020.06.026. Epub 2020 Jun 26.
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Tatiana Korotkova
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Leo Kurian
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Negrete-Hurtado A, Overhoff M, Bera S, De Bruyckere E, Schätzmüller K, Kye MJ, Qin C, Lammers M, Kondylis V, Neundorf I, Kononenko N (2020). Autophagy lipidation machinery regulates axonal microtubule dynamics but is dispensable for survival of mammalian neurons. Nat Commun. 2020; 11: 1535. Published online 2020 Mar 24. doi: 10.1038/s41467-020-15287-9
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Maria Leptin
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Manolis Pasparakis
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Schwarzer R, Jiao H, Wachsmuth L, Tresch A, Pasparakis M (2020). FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells. Immunity. 2020 Apr 22. pii: S1074-7613(20)30160-6. doi: 10.1016/j.immuni.2020.04.002. [Epub ahead of print]
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Pedragosa J, Miró-Mur F, Otxoa-de-Amezaga A, Justicia C, Ruíz-Jaén F, Ponsaerts P, Pasparakis M, Planas AM (2020). CCR2 deficiency in monocytes impairs angiogenesis and functional recovery after ischemic stroke in mice. J Cereb Blood Flow Metab. 2020 Dec;40(1_suppl):S98-S116. doi: 10.1177/0271678X20909055. Epub 2020 Mar 9. PMID: 32151226
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Lena Pernas
Machado TS, Carvalho DF, Garcia BM, Zangirolamo AF, Macabelli CH, Sugiyama FHC, Grejo MP, Neto JDA, Ribeiro FKS, Sarapião FD, Meirelle FV, Guimarães FEG, Pernas L, Seneda MM, Chiaratti MR (2020).Mitofusin 1 is required for oocyte growth and communication with follicular somatic cells. FASEB J. doi: 10.1096/fj.201901761R. PMID: 32281181
Christina Polidori
La Colla L, Polidori MC, Di Saverio G, Preziosi G, Mantovani L, Caobelli F (2020). The impact of health worker gap in Italy on the COVID-19 pandemic. A good time to improve the quality of the Italian National Health System (NHS)? J Infect Public Health. 2020 Sep;13(9):1253-1254. doi: 10.1016/j.jiph.2020.06.010. Epub 2020 Jun 15. PMID: 32586683
Rarek MP, Meyer AM, Pickert L, Pilotto A, Benzing T, Burst V, Polidori MC (2020). The prognostic signature of health-related quality of life in older patients admitted to the emergency department: a 6-month follow-up study. Aging Clin Exp Res. 2020 Nov 1. doi: 10.1007/s40520-020-01732-8. Online ahead of print. PMID: 33135133
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Cruz-Jentoft AJ, Daragjati J, Fratiglioni L, Maggi S, Mangoni AA, Mattace-Raso F, Paccalin M, Polidori MC, Topinkova E, Ferrucci L, Pilotto A on behalf of the MPI_AGE Investigators (2020). New Horizons in Comprehensive Geriatric Assessment: the Multidimensional Prognostic Index (MPI). Results and Recommendations from the MPI_AGE Project. Aging Clin Exp Res. 2020 Mar 16
Ungar A, Rivasi G, Petrovic M, Schönenberger A, Martínez-Sellés M, Gasowski J, Bahat-Ozturk G, Bo M, Dallmaier D, Fumagalli S, Grodzicki T, Kotovskaya Y, Maggi S, Raso FM, Polidori MC, Rajkumar R, Strandberg T, Werner N, Benetos A; From the EuGMS Special Interest Group on Cardiovascular Medicine (2020). Toward a geriatric approach to patients with advanced age and cardiovascular diseases: position statement of the EuGMS Special Interest Group on Cardiovascular Medicine.Eur Geriatr Med. 2020 Feb;11(1):179-184
Polidori MC, Maggi S, Mattace Raso F, Pilotto A (2020). The unavoidable costs of frailty: a geriatric perspective in the time of COVID-19. Geriatric Care. 2020; 6: 8989
Custodero C, Cella A, Veronese N, Azzini M, Fimognari F, Mattace-Raso F, Polidori MC, Sabbà C, Pilotto A. (2020). The Multidimensional Prognostic Index (MPI) for the prognostic stratification of hospitalized older patients with COVID-19: a prospective multicenter observational cohort study. Objectives, study design and expected outcomes (MPI_COVID-19). Geriatric Care.doi.org/10.4081/gc.2020.9038
Jacobs AH, Emmert K, Baron R, Bartsch T, Bauer J, Becker C, Berg D, Bergmann P, Boetzel K, Bollheimer C, Deuschl G, Djukic M, Drey M, Durwen H, Ebersbach G, Elshehabi M, Geritz J, Gisinger C, Guennewig T, Hauptmann B, Heppner HJ, Hobert MA, Hofmann W, Huellemann P, Jahn K, Klucken J, Kurth R, Lindner R, Lingor P, Lukas A, Maetzold S, Mokrusch T, Mollenhauer B, Nau R, Plate A, Polidori MC, Prell T, Schellinger P, Schuetze S, Spira D, Stephani U, Studt S, Trenkwalder C, Unger HL, Urban P, von Arnim C, Warnecke T, Weiss M, Wiedemann A, Wirth R, Witt K, Dodel R, Maetzler W (2020). Neurogeriatrics – a vision for improved care and research for geriatric patients with leading neurological disabilities. Z Gerontol Geriatr. 2020 (53) 340-346
Falkenreck JM, Roheger M,Weigert H,Friese A,Jahr P, Becker I,Nelles G,Kalbe E,Polidori MC (2020). BrainProtect® - a cognitive training program with nutritional and physical counseling components: a retrospective analysis of its effects in healthy individuals. Geriatric Care. doi.org/10.4081/gc.2020.9328
Polidori MC Section Editor. Ageing Medicine and Geriatrics. In: Encyclopedia of Gerontology and Population Aging. Gu D and Dupre M Eds. Springer 2020
Senin U, Polidori MC, Cherubini A, Mecocci P (2020). Paziente Anziano Paziente Geriatrico Medicina della Complessitá. Fondamenti di Gerontologia e Geriatria. Eds. 4th Edition, Edises, Napoli 2020
Simon Pöpsel
Finogenova K, Bonnet J, Poepsel S, Schäfer IB, Finkl K, Schmid K, Litz C, Strauss M, Benda C, Müller J (2020). Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3. Elife. 2020 Nov 19;9:e61964. doi: 10.7554/eLife.61964.
Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hoevelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling CD, Hartmann E, Rosenwald A, Klapper W, Buettner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt C, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2020). -Active AKT signaling triggers CLL towards Richter's transformation via over-activation of Notch1. Blood. 2020 Nov 2:blood.2020005734. doi: 10.1182/blood.2020005734. Online ahead of print. PMID: 33140819
Reimann M, Schrezenmeier JF, Richter-Pechanska P, Dolnik A, Hick TP, Schleich K, Cai X, Fan DNY, Lohneis P, Masswig S, Denker S, Busse A, Knittel G, Flümann R, Childs D, Childs L, Gätjens-Sanchez AM, Bullinger L, Rosenwald A, Reinhardt HC, Schmitt CA (2020). Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas. Blood. 2020 Nov 24:blood.2020005244. doi: 10.1182/blood.2020005244. Online ahead of print. PMID: 33232972
Zimmer Y, Reinhardt HC, Medová M (2020). Editorial: Exploiting DNA Damage Response in the Era of Precision Oncology. Front Oncol. 2020 Oct 15;10:611127. doi: 10.3389/fonc.2020.611127. eCollection 2020. PMID: 33178619
Chen Y, Hoffmeister LM, Zaun Y, Arnold L, Schmid KW, Giebel B, Klein-Hitpass L, Hanenberg H, Squire A, Reinhardt HC, Dührsen U, Bertram S, Hanoun M (2020). Acute myeloid leukemia-induced remodeling of the human bone marrow niche predicts clinical outcome. Blood Adv. 2020 Oct 27;4(20):5257-5268. doi: 10.1182/bloodadvances.2020001808. PMID: 33108453
Jakobs F, Drost RMWA, Kron A, Heinen J, Hallek M, Reinhardt HC, Zander T, Kron F (2020). Economic Impact of the Introduction of Outpatient Medical Specialist Care (ASV) of Gastrointestinal Cancer Patients from a German Hospital Management Perspective. Oncol Res Treat. 2020;43(10):498-505. doi: 10.1159/000509618. Epub 2020 Sep 21. PMID: 32957103
Gremke N, Polo P, Dort A, Schneikert J, Elmshäuser S, Brehm C, Klingmüller U, Schmitt A, Reinhardt HC, Timofeev O, Wanzel M, Stiewe T (2020). mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability. Nat Commun. 2020 Sep 17;11(1):4684. doi: 10.1038/s41467-020-18504-7. PMID: 32943635
Johansson P, Klein-Hitpass L, Röth A, Möllmann M, Reinhardt HC, Dührsen U, Dürig J (2020). Mutations in PIGA cause a CD52-/GPI-anchor-deficient phenotype complicating alemtuzumab treatment in T-cell prolymphocytic leukemia. Eur J Haematol. 2020 Dec;105(6):786-796. doi: 10.1111/ejh.13511. Epub 2020 Sep 28. PMID: 32875608
Schödel P, Jünger ST, Wittersheim M, Reinhardt HC, Schmidt NO, Goldbrunner R, Proescholdt M, Grau S (2020). Surgical resection of symptomatic brain metastases improves the clinical status and facilitates further treatment. Cancer Med. 2020 Oct;9(20):7503-7510. doi: 10.1002/cam4.3402. Epub 2020 Aug 28. PMID: 32858763
Klein S, Quaas A, Noh KW, Cartolano M, Abedpour N, Mauch C, Quantius J, Reinhardt HC, Buettner R, Peifer M, Helbig D (2020). Integrative Analysis of Pleomorphic Dermal Sarcomas Reveals Fibroblastic Differentiation and Susceptibility to Immunotherapy. Clin Cancer Res. 2020 Nov 1;26(21):5638-5645. doi: 10.1158/1078-0432.CCR-20-1899. Epub 2020 Aug 17. PMID: 32817080
Kong YW, Dreaden EC, Morandell S, Zhou W, Dhara SS, Sriram G, Lam FC, Patterson JC, Quadir M, Dinh A, Shopsowitz KE, Varmeh S, Yilmaz ÖH, Lippard SJ, Reinhardt HC, Hemann MT, Hammond PT, Yaffe MB (2020). Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints. Nat Commun. 2020 Aug 17;11(1):4124. doi: 10.1038/s41467-020-17958-z. PMID: 32807787
Koch M, Reinartz S, Saggau J, Knittel G, Rosen N, Fedorchenko O, Thelen L, Barthel R, Reinart N, Seeger-Nukpezah T, Reinhardt HC, Hallek M, Nguyen PH (2020). Meta-Analysis Reveals Significant Sex Differences in Chronic Lymphocytic Leukemia Progression in the Eµ-TCL1Transgenic Mouse Model. Cancers (Basel). 2020 Jul 20;12(7):1980. doi: 10.3390/cancers12071980. PMID: 32698538
Spiro JE, Rinneburger M, Hedderich DM, Jokic M, Reinhardt HC, Maintz D, Palmowski M, Persigehl T (2020). Monitoring treatment effects in lung cancer-bearing mice: clinical CT and clinical MRI compared to micro-CT. Eur Radiol Exp. 2020 May 13;4(1):31. doi: 10.1186/s41747-020-00160-7. PMID: 32399584
Jachimowicz RD, Pieper L, Reinke S, Gontarewicz A, Plütschow A, Haverkamp H, Frauenfeld L, Fend F, Overkamp M, Jochims F, Thorns C, Hansmann ML, Möller P, Rosenwald A, Stein H, Reinhardt HC, Borchmann P, von Tresckow B, Engert A, Klapper W (2020). Analysis of the tumor microenvironment by whole-slide image analysis identifies low B cell content as a predictor of adverse outcome in advanced-stage classical Hodgkin lymphoma treated with BEACOPP. Haematologica. 2020 May 7. doi: 10.3324/haematol.2019.243287. Online ahead of print. PMID: 32381573
Volz C, Breid S, Selenz C, Zaplatina A, Golfmann K, Meder L, Dietlein F, Borchmann S, Chatterjee S, Siobal M, Schöttle J, Florin A, Koker M, Nill M, Ozretić L, Uhlenbrock N, Smith S, Büttner R, Miao H, Wang B, Reinhardt HC, Rauh D, Hallek M, Acker-Palmer A, Heukamp LC, Ullrich RT (2020). Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC. Cell Rep. 2020 Apr 28;31(4):107568. doi: 10.1016/j.celrep.2020.107568. PMID: 32348765
Flümann R, Nieper P, Reinhardt HC, Knittel G (2020). New murine models of aggressive lymphoma. Leuk Lymphoma. 2020 Apr;61(4):788-798. doi: 10.1080/10428194.2019.1691200. Epub 2019 Nov 22. PMID: 31752573
Bendell JC, Bischoff HG, Hwang J, Reinhardt HC, Zander T, Wang X, Hynes S, Pitou C, Campbell R, Iversen P, Farrington DL, Bell-McGuinn K, Thomas M (2020). A phase 1 dose-escalation study of checkpoint kinase 1 (CHK1) inhibitor prexasertib in combination with p38 mitogen-activated protein kinase (p38 MAPK) inhibitor ralimetinib in patients with advanced or metastatic cancer. Invest New Drugs. 2020 Aug;38(4):1145-1155. doi: 10.1007/s10637-019-00873-6. Epub 2019 Nov 9. PMID: 31707688
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Kreuzer KA, Furman RR, Stilgenbauer S, Dubowy RL, Kim Y, Munugalavadla V, Lilienweiss E, Reinhardt HC, Cramer P, Eichhorst B, Hillmen P, O'Brien SM, Pettitt AR, Hallek M (2020). The impact of complex karyotype on the overall survival of patients with relapsed chronic lymphocytic leukemia treated with idelalisib plus rituximab. Leukemia. 2020 Jan;34(1):296-300. doi: 10.1038/s41375-019-0533-6. Epub 2019 Aug 19. PMID: 31427720
Finger Y, Habich M, Gerlich S, Urbanczyk S, Logt E, Koch J, Schu L, Lapacz KJ, Ali M, Petrungaro C, Salscheider SL, Pichlo C, Baumann U, Mielenz D, Brachvogel B, Hofmaann K, Riemer J (2020). Proteasomal degradation induced by DPP9‐mediated processing competes with mitochondrial protein import. EMBO J. 2020 Oct 1; 39(19): e103889. 2020 Aug 20. doi: 10.15252/embj.2019103889
Szczepanowska K, Senft K, Heidler J, Herholz M, Kukat A, Höhne MN, Hofsetz E, Becker C, Kaspar S, Giese H, Zwicker K, Guerrero-Castillo S, Baumann L, Kauppila J, Rumyantseva A, Müller S, Frese CK, Brandt U, Riemer J, Wittig I, Trifunovic A (2020). A salvage pathway maintains highly functional respiratory complex I. Nat Commun. 2020 Apr 2;11(1):1643. doi: 10.1038/s41467-020-15467-7
Herrmann JM, Riemer J (2020). Apoptosis inducing factor and mitochondrial NADH dehydrogenases: redox-controlled gear boxes to switch between mitochondrial biogenesis and cell death. Biol Chem. 2020 Aug 25;402(3):289-297. doi: 10.1515/hsz-2020-0254
Murschall LM, Gerhards A, MacVicar T, Peker E, Hasberg L, Wawra S, Langer T, Riemer J (2020). The C-terminal region of the oxidoreductase MIA40 stabilizes its cytosolic precursor during mitochondrial import. BMC Biol. 2020 Aug 6;18(1):96. doi.org/10.1186/s12915-020-00824-1
Finger Y, Riemer J (2020). Protein import by the mitochondrial disulfide relay in higher eukaryotes. Biol Chem. 2020 May 26;401(6-7):749-763. doi: 10.1515/hsz-2020-0108
Stavru F, Riemer J, Jex A, Sassera D (2020). When bacteria meet mitochondria: The strange case of the tick symbiont Midichloria mitochondrii. Cell Microbiol. 2020 Apr;22(4):e13189. doi: 10.1111/cmi.13189
Nirmal Robinson
Hos NJ, Fischer J, Hos D, Hejazi Z, Calabrese C, Ganesan R, Murthy AMV, Rybniker J, Kumar S, Krönke M, Robinson N (2020). TRIM21 Is Targeted for Chaperone-Mediated Autophagy during SalmonellaTyphimurium Infection. J Immunol. 2020 Sep 18:ji2000048. doi: 10.4049/jimmunol.2000048. Online ahead of print. PMID: 32948684
Kew C, Huang W, Fischer J, Ganesan R, Robinson N, Antebi A (2020). Evolutionarily conserved regulation of immunity by the splicing factor RNP-6/PUF60. Elife. 2020 Jun 15;9:e57591. doi: 10.7554/eLife.57591
Pla-Martín D, Schatton D, Wiederstein JL, Marx MC, Khiati S, Krüger M, Rugarli EI (2020). CLUH granules coordinate translation of mitochondrial proteins with mTORC1 signaling and mitophagy. EMBO J. 2020 May 4;39(9):e102731. doi: 10.15252/embj.2019102731. Epub 2020 Mar 9. PMID: 32149416
Tadepalle N, Robers L, Veronese M, Zentis P, Babatz F, Brodesser S, Gruszczyk AV, Schauss A, Hoening S, Rugarli EI (2020). Microtubule-dependent and independent roles of spastin in lipid droplet dispersion and biogenesis.Life Sci Alliance. 2020 Apr 22;3(6):e202000715. doi: 10.26508/lsa.202000715. Print 2020 Jun
Lopes AFC, Bozek K, Herholz M, Trifunovic A, Rieckher M, Schumacher B (2020). A C. elegans model for neurodegeneration in Cockayne syndrome. Nucleic Acids Res. 2020, gkaa795, doi.org/10.1093/nar/gkaa795
Meyer DH, Schumacher B (2020). A transcriptome based aging clock near the theoretical limit of accuracy. BioRxiv 2020; doi: doi.org/10.1101/2020.05.29.123430
Umansky C, Morellato A, Scheidegger M, Rieckher M, Martinefski MR, Fernandez GA, Kolesnikova K, Vesting AJ, Karakasilioti I, Reingruber H, Wei Y, He R, Bollini M, Monge ME, Schumacher B, Pontel LB (2020). Endogenous formaldehyde scavenges cellular glutathione resulting in cytotoxic redox disruption. BioRxiv 2020; dio doi.org/10.1101/2020.05.14.090738
Bansal A, Neuhaus R, Izquierdo-Alvarez E, Vorholt D, Feldkötter H, Nolte H, Lohneis P, Büttner R, Krüger M, Pallasch CP, Schumacher B (2020). ATM-mediated DNA damage response in macrophages primes phagocytosis and immune checkpoint regulation. BioRxiv 2020; doi: doi.org/10.1101/2020.03.14.987438
Chatzidoukaki O, Goulielmaki E, Schumacher B, Garinis GA (2020). DNA Damage Response and Metabolic Reprogramming in Health and Disease. Trends Genet. 2020 Jul 16:S0168-9525(20)30166-9- doi.org/10.1016/j.tig.2020.06.018
Wang S, Meyer DH, Schumacher B (2020). H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage. Nat Struct Mol Biol. (2020). doi.org/10.1038/s41594-020-00513-1
Gebel J, Tuppi M, Sänger N, Schumacher B, Dötsch V (2020). DNA Damaged Induced Cell Death in Oocytes. Molecules. 2020 Dec 3;25(23):E5714. doi: 10.3390/molecules25235714Gebel J, Tuppi M, Sänger N, Schumacher B, Dötsch V (2020). DNA Damaged Induced Cell Death in Oocytes. Molecules. 2020 Dec 3;25(23):E5714. doi: 10.3390/molecules25235714
Philipp Steven
Gehlsen U, Siebelmann S, Steven P. Tolerance and Adherence to Cationic 0.1% Cyclosporine in Ocular Graft-versus-Host Disease. Ophthalmic Res. 2021;64(1):77-84. doi: 10.1159/000509034. Epub 2020 May 29. PubMed PMID: 32474565.
Tahmaz V, Wiesen MHJ, Gehlsen U, Sauerbier L, Stern ME, Holtick U, Gathof B, Scheid C, Müller C, Steven P. Detection of systemic immunosuppressants in autologous serum eye drops (ASED) in patients with severe chronic ocular graft versus host disease. Graefes Arch Clin Exp Ophthalmol. 2021 Jan;259(1):121-128.doi: 10.1007/s00417-020-04865-8. Epub 2020 Aug 19. PubMed PMID: 32812133; PubMed Central PMCID: PMC7790777.
Osae EA, Ablordeppey RK, Horstmann J, Kumah DB, Steven P (2020). Clinical Dry Eye and Meibomian Gland Features Among Dry Eye Patients in Rural and Urban Ghana. Clin Ophthalmol. 2020;14:4055-4063. doi: 10.2147/OPTH.S275584. eCollection 2020. PubMed PMID: 33262570; PubMed Central PMCID: PMC7699986.
Osae EA, Bullock T, Chintapalati M, Brodesser S, Hanlon S, Redfern R, Steven P, Smith CW, Rumbaut RE, Burns AR. Obese Mice with Dyslipidemia Exhibit Meibomian Gland Hypertrophy and Alterations in Meibum Composition and Aqueous Tear Production.Int J Mol Sci. 2020 Nov 20;21(22). doi: 10.3390/ijms21228772. PubMed PMID: 33233559; PubMed Central PMCID: PMC7699756.
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Steven P, Faust C, Holtick U, Scheid C, Tahmaz V, Stern ME, Gehlsen U. Adverse environmental conditions are a risk factor for ocular GvHD after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2020 Sep;55(9):1851-1853. doi: 10.1038/s41409-020-0824-6. Epub 2020 Feb 10. PubMed PMID: 32042103.
Schwarzer R, Jiao H, Wachsmuth L, Tresch A, Pasparakis M (2020). FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells. Immunity. 2020 Jun 16;52(6):978-993.e6. doi: 10.1016/j.immuni.2020.04.002. Epub 2020 May 1
Marc Tittgemeyer
Kostić D, Hilgetag CC, Tittgemeyer M (2020). Unifying the essential concepts of biological networks: biological insights and philosophical foundations. Philos Trans R Soc Lond B Biol Sci. 2020 Apr 13;375(1796):20190314. doi: 10.1098/rstb.2019.0314. Epub 2020 Feb 24. PMID: 32089117
Alicart H, Obst M, Heldmann M, Göttlich M, Tittgemeyer M, Münte T (2020). Modulation of visual processing of food by transcutaneous vagus nerve stimulation (tVNS). Brain Imaging Behav. 2020 Sep 14. doi: 10.1007/s11682-020-00382-8. Online ahead of print
Cole D, Diaconescu A, Pfeiffer U, Brodersen K, Mathys C, Julkowski D, Ruhrmann S, Schilbach L, Tittgemeyer M, Vogeley K, Stephan K (2020). Atypical processing of uncertainty in individuals at risk for psychosis. Neuroimage Clin. 2020;26:102239. doi: 10.1016/j.nicl.2020.102239. Epub 2020 Mar 7
Edwin Thanarajah S, Tittgemeyer M (2020). Food reward and gut-brain signaling. Neuroforum. 26(1), 1-9
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David Vilchez
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Silvia von Karstedt
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Johannes Vogt
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