CECAD

Publikationen 2021

A B C​​​​​​ D E F G​​​​​​ H I J​​​​​​​ K​​​​​​​ L​​​​​​​ M N O P​​​​​​​ Q​​​​​​​ R​​​​​​​ S​​​​​​​ T​​​​​​​U​​​​​​​ V​​​​​​​ W​​​​​​​ X​​​​​​​ Y​​​​​​​ Z​​​​​​​​​​​​​​​​​​​​​

Adam Antebi

  • Schiffer I, Gerisch B, Kawamura K, Laboy R, Hewitt J, Denzel MS, Mori MA, Vanapalli S, Shen Y, Symmons O, Antebi A (2021). miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to affect muscle contractility upon proteotoxic challenge during ageing. biorxiv. doi: doi.org/10.1101/2021.01.21.427623 
  • Ellwood RA, Hewitt JE, Torregrossa R, Philp AM, Hardee JP, Hughes S, van de Klashorst D, Gharahdaghi N, Anupom T, Slade L, Deane CS, Cooke M, Etheridge T, Piasecki M, Antebi A, Lynch GS, Philp A, Vanapalli SA, Whiteman M, Szewczyk NJ (2021). Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2018342118. doi: 10.1073/pnas.2018342118. PMID: 33627403
  • Allmeroth K, Kim CS, Annibal A, Pouikli A, Koester J, Derisbourg MJ, Andrés Chacón-Martínez C, Latza C, Antebi A, Tessarz P, Wickström SA, Denzel MS. N1-acetylspermidine is a determinant of hair follicle stem cell fate. J Cell Sci. 2021 May 1;134(9):jcs252767. doi: 10.1242/jcs.252767. Epub 2021 May 11. PMID: 33973637. 
  • Annibal A, Tharyan RG, Schonewolff MF, Tam H, Latza C, Auler MMK, Antebi A (2021). Regulation of the one carbon folate cycle as a shared metabolic signature of longevity. Nat Commun. 2021 Jun 9;12(1):3486. doi: 10.1038/s41467-021-23856-9. PMID: 34108489.

Hisham Bazzi

  • Phan TP, Maryniak AL, Boatwright CA, Lee J, Atkins A, Tijhuis A, Spierings DC, Bazzi H, Foijer F, Jordan PW, Stracker TH, Holland AJ (2021). Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway. EMBO J. 2021 Jan 4;40(1):e106118. doi: 10.15252/embj.2020106118. Epub 2020 Nov 23   
  • Xiao C, Grzonka M, Meyer-Gerards C, Mack M, Figge R, Bazzi H (2021). Gradual centriole maturation associates with the mitotic surveillance pathway in mouse development. EMBO Rep. 2021 Jan 7:e51127. doi: 10.15252/embr.202051127. Online ahead of print. PMID: 33410253 
  • Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H (2021). High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227. doi: 10.1038/s41467-021-23386-4. PMID: 34050161; PMCID: PMC8163813.

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Thomas Benzing

  • Pickert L, Meyer AM, Becker I, Heeß A, Noetzel N, Brinkkötter P, Pilotto A, Benzing T, Polidori MC (2021). Role of a multidimensional prognosis in-hospital monitoring for older patients with prolonged stay. Int J Clin Pract. 2021 Jan 6:e13989. doi: 10.1111/ijcp.13989. Online ahead of print. PMID: 33406298 
  • Polidori MC, Sies H, Ferrucci L, Benzing T (2021). COVID-19 mortality as a fingerprint of biological age. Ageing Res Rev. 2021 May;67:101308. doi: 10.1016/j.arr.2021.101308. Epub 2021 Feb 20. PMID: 33621704; PMCID: PMC7896489. 
  • Benzing T, Salant D (2021). Insights into Glomerular Filtration and Albuminuria. N Engl J Med. 2021 Apr 15;384(15):1437-1446. doi: 10.1056/NEJMra1808786. PMID: 33852781.
  • Talyan S, Filipów S, Ignarski M, Smieszek M, Chen H, Kühne L, Butt L, Göbel H, Hoyer-Allo KJR, Koehler FC, Altmüller J, Brinkkötter P, Schermer B, Benzing T, Kann M, Müller RU, Dieterich C. CALINCA-A Novel Pipeline for the Identification of lncRNAs in Podocyte Disease. Cells. 2021 Mar 20;10(3):692. doi: 10.3390/cells10030692. PMID: 33804736; PMCID: PMC8003990.
  • He B, Chen P, Zambrano S, Dabaghie D, Hu Y, Möller-Hackbarth K, Unnersjö-Jess D, Korkut GG, Charrin E, Jeansson M, Bintanel-Morcillo M, Witasp A, Wennberg L, Wernerson A, Schermer B, Benzing T, Ernfors P, Betsholtz C, Lal M, Sandberg R, Patrakka J. Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes. Nat Commun. 2021 Apr 9;12(1):2141. doi: 10.1038/s41467-021-22331-9. PMID: 33837218; PMCID: PMC8035407. 
  • Hoyer-Allo KJR, Späth MR, Hanssen R, Johnsen M, Brodesser S, Kaufmann K, Kiefer K, Koehler FC, Göbel H, Kubacki T, Grundmann F, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2021). Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury. Int J Mol Sci. 2021 May 22;22(11):5485. doi: 10.3390/ijms22115485. PMID: 34067475; PMCID: PMC8196977.

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Andreas Beyer

  • Lackner A, Sehlke R, Garmhausen M, Giuseppe Stirparo G, Huth M, Titz-Teixeira F, van der Lelij P, Ramesmayer J, Thomas HF, Ralser M, Santini L, Galimberti E, Sarov M, Stewart AF, Smith A, Beyer A, Leeb M (2021). Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency. EMBO J. 2021 Mar 9:e105776. doi: 10.15252/embj.2020105776. Online ahead of print. PMID: 33687089
  • Tain LS, Sehlke R, Meilenbrock RL, Leech T, Paulitz J, Chokkalingam M, Nagaraj N, Grönke S, Fröhlich J, Atanassov I, Mann M, Beyer A, Partridge L. Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila. Elife. 2021 Apr 21;10:e67275. doi: 10.7554/eLife.67275. PMID: 33879316; PMCID: PMC8060030.
  • Tognetti M, Gabor A, Yang M, Cappelletti V, Windhager J, Rueda OM, Charmpi K, Esmaeilishirazifard E, Bruna A, de Souza N, Caldas C, Beyer A, Picotti P, Saez-Rodriguez J, Bodenmiller B. Deciphering the signaling network of breast cancer improves drug sensitivity prediction. Cell Syst. 2021 Apr 27:S2405-4712(21)00111-3. doi: 10.1016/j.cels.2021.04.002. Epub ahead of print. PMID: 33932331.
  • He F, Steige KA, Kovacova V, Göbel U, Bouzid M, Keightley PD, Beyer A, de Meaux J (2021). Cis-regulatory evolution spotlights species differences in the adaptive potential of gene expression plasticity. Nat Commun. 2021 Jun 7;12(1):3376. doi: 10.1038/s41467-021-23558-2. PMID: 34099660; PMCID: PMC8184852.

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Jens Brüning  

  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798
  • Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC(2021). Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat Neurosci. 2021 May 17. doi: 10.1038/s41593-021-00854-0. Epub ahead of print. PMID: 34002087.
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning JC, Langer T, Braun T, Krüger M (2021).Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. Feb 5;154:41-59. doi: 10.1016/j.yjmcc.2021.01.010.Online ahead of print.
  • Hanssen, R, Kretschmer AC, Rigoux L, Albus K, Edwin Thanarajah S, Sitnikow T, Melzer C, Cornely OA, Brüning JC, Tittgemeyer M (2021). GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans. Mol Metab. Jan 14;45:101163. doi: 10.1016/j.molmet.2021.101163. Online ahead of print 
  • Dodd GT, Kim SJ, Méquinion M, Xirouchaki CE, Brüning JC, Andrews ZB, Tiganis T (2021). Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance. Sci Adv. 2021 Feb 26;7(9):eabf4100. doi: 10.1126/sciadv.abf4100. Print 2021 Feb. PMID: 33637536 
  • Quarta C, Claret M, Zeltser LM, Williams KW, Yeo GSH, Tschöp MH, Diano S, Brüning JC, Cota D (2021). POMC neuronal heterogeneity in energy balance and beyond: an integrated view. Nat Metab. 2021 Feb 25. doi: 10.1038/s42255-021-00345-3. Online ahead of print. PMID: 33633406 Review. 
  • Borgmann D, Ciglieri E, Biglari N, Brandt C, Cremer AL, Backes H, Tittgemeyer M, Wunderlich FT, Brüning JC, Fenselau H (2021). Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metab. 2021 May 21:S1550-4131(21)00219-9. doi: 10.1016/j.cmet.2021.05.002. Epub ahead of print. PMID: 34043943.
  • Hoyer-Allo KJR, Späth MR, Hanssen R, Johnsen M, Brodesser S, Kaufmann K, Kiefer K, Koehler FC, Göbel H, Kubacki T, Grundmann F, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2021). Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury. Int J Mol Sci. 2021 May 22;22(11):5485. doi: 10.3390/ijms22115485. PMID: 34067475; PMCID: PMC8196977.

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Oliver Cornely

  • Koehler P, Cornely OA, Kochanek M (2021). Bronchoscopy safety precautions for diagnosing COVID-19 associated pulmonary aspergillosis-A simulation study. Mycoses. 2021 Jan;64(1):55-59. doi: 10.1111/myc.13183. Epub 2020 Sep 26. PMID: 32918497
  • Budin S, Salmanton-García J, Koehler P, Stemler J, Cornely OA, Mellinghoff SC (2021). Validation of the EQUAL Aspergillosis Score by analysing guideline-adherent management of invasive pulmonary aspergillosis. J Antimicrob Chemother. 2021 Jan 4:dkaa518. doi: 10.1093/jac/dkaa518. Online ahead of print. PMID: 33394007
  • Chen SC, Halliday CL, Hoenigl M, Cornely OA, Meyer W (2021). Scedosporium and LomentosporaInfections: Contemporary Microbiological Tools for the Diagnosis of Invasive Disease. J Fungi (Basel). 2021 Jan 4;7(1):E23. doi: 10.3390/jof7010023. PMID: 33406673 Review.
  • van Werkhoven CH, Ducher A, Berkell M, Mysara M, Lammens C, Torre-Cisneros J, Rodríguez-Baño J, Herghea D, Cornely OA, Biehl LM, Bernard L, Dominguez-Luzon MA, Maraki S, Barraud O, Nica M, Jazmati N, Sablier-Gallis F, de Gunzburg J, Mentré F, Malhotra-Kumar S, Bonten MJM, Vehreschild MJGT; ANTICIPATE Study Group. Incidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics. Nat Commun. 2021 Apr 14;12(1):2240. doi: 10.1038/s41467-021-22269-y. PMID: 33854064.
  • Hanssen R, Kretschmer AC, Rigoux L, Albus K, Thanarajah SE, Sitnikow T, Melzer C, Cornely OA, Brüning JC, Tittgemeyer M (2021). GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans. Mol Metab. 2021 Jan 13:101163. doi: 10.1016/j.molmet.2021.101163. Online ahead of print. PMID: 33453418
  • Christopeit M, Schmidt-Hieber M, Sprute R, Buchheidt D, Hentrich M, Karthaus M, Penack O, Ruhnke M, Weissinger F, Cornely OA, Maschmeyer G (2021). Prophylaxis, diagnosis and therapy of infections in patients undergoing high-dose chemotherapy and autologous haematopoietic stem cell transplantation. 2020 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO). Ann Hematol. 2021 Feb;100(2):321-336. doi: 10.1007/s00277-020-04297-8. Epub 2020 Oct 20. PMID: 33079221
  • Wunsch S, Zurl C, Strohmaier H, Meinitzer A, Rabensteiner J, Posch W, Lass-Flörl C, Cornely O, Pregartner G, König E, Feierl G, Hoenigl M, Prattes J, Zollner-Schwetz I, Valentin T, Krause R (2021). Longitudinal Evaluation of Plasma Cytokine Levels in Patients with Invasive Candidiasis. J Fungi (Basel).2021 Feb 1;7(2):101. doi: 10.3390/jof7020101. PMID: 33535593
  • Banck JC, Mueller N, Mellinghoff SC, Thelen M, Fraccaroli A, Blumenberg V, Koehler P, Kunz WG, Rudelius M, Schrötzlmair F, Subklewe M, Schlößer HA, Tischer J, Cornely OA, Lindner LH, von Bergwelt-Baildon M (2021). Immune Checkpoint Blockade for Aspergillosis and Mucormycosis Coinfection. Hemasphere. 2021 Feb 10;5(3):e530. doi: 10.1097/HS9.0000000000000530. eCollection 2021 Mar. PMID: 33604513
  • Hoenigl M, Levitz SM, Schuetz AN, Zhang SX, Cornely OA (2021). All You Need to Know and More about the Diagnosis and Management of Rare Mold Infections. mBio. 2021 Feb 23;12(1):e02920-20. doi: 10.1128/mBio.02920-20. PMID: 33622731
  • Sprute R, Seidel D, Cornely OA, Hoenigl M (2021). EHA Endorsement of the Global Guideline for the Diagnosis and Management of Rare Mold Infection: An Initiative of the European Confederation of Medical Mycology in Cooperation With International Society for Human and Animal Mycology and American Society for Microbiology. Hemasphere. 2021 Feb 23;5(3):e519. doi: 10.1097/HS9.0000000000000519. eCollection 2021 Mar. PMID: 33644696 No abstract available
  • Giesen N, Sprute R, Rüthrich M, Khodamoradi Y, Mellinghoff SC, Beutel G, Lueck C, Koldehoff M, Hentrich M, Sandherr M, von Bergwelt-Baildon M, Wolf HH, Hirsch HH, Wörmann B, Cornely OA, Köhler P, Schalk E, von Lilienfeld-Toal M; COVID-19 guideline panel of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO) (2021). 2021 update of the AGIHO guideline on evidence-based management of COVID-19 in patients with cancer regarding diagnostics, viral shedding, vaccination and therapy. Eur J Cancer. 2021 Feb 10;147:154-160. doi: 10.1016/j.ejca.2021.01.033. Online ahead of print. PMID: 33676266
  • Meinberger D, Koch M, Roth A, Hermes G, Stemler J, Cornely OA, Streichert T, Klatt AR. Analysis of IgM, IgA, and IgG isotype antibodies Directed against SARS-CoV-2 spike glycoprotein and ORF8 in the course of COVID-19. Sci Rep. 2021 Apr 26;11(1):8920. doi: 10.1038/s41598-021-88356-8. PMID: 33903660; PMCID: PMC8076237. 
  • Classen AY, Henze L, von Lilienfeld-Toal M, Maschmeyer G, Sandherr M, Graeff LD, Alakel N, Christopeit M, Krause SW, Mayer K, Neumann S, Cornely OA, Penack O, Weißinger F, Wolf HH, Vehreschild JJ (2021).Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematologic malignancies and solid tumors: 2020 updated guidelines of the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology (AGIHO/DGHO). Ann Hematol. 2021 Jun;100(6):1603-1620. doi: 10.1007/s00277-021-04452-9. Epub 2021 Apr 13. PMID: 33846857; PMCID: PMC8116237. 
  • Stemler J, Cornely OA, Noack-Schönborn T, Fohrholz C, Schumacher S, Poluschkin L, Binder B, Lehmann C, Langebartels G (2021). Web-based, rapid and contactless management of ambulatory patients for SARS-CoV-2-testing. BMC Infect Dis. 2021 Jun 7;21(1):535. doi: 10.1186/s12879-021-06249-7. PMID: 34098882; PMCID: PMC8182346.

 

Joris Deelen

  • Deelen J (2021). Targeting multimorbidity: Using healthspan and lifespan to identify biomarkers of ageing that pinpoint shared disease mechanisms. EBioMedicine. 2021 May;67:103364. doi: 10.1016/j.ebiom.2021.103364. Epub 2021 May 6. PMID: 33965870; PMCID: PMC8114127.

 

Constantinos Demetriades

  • Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G, Genomics England Research Consortium, de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K (2021). G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling. Cell. 2021 Jan 18:S0092-8674(20)31694-9. doi: 10.1016/j.cell.2020.12.024. Online ahead of print. PMID: 33497611
  • Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D. TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. Mol Cell. 2021 Apr 30:S1097-2765(21)00324-5. doi: 10.1016/j.molcel.2021.04.019. Epub ahead of print. PMID: 33974911.

Martin Denzel

  • Schiffer I, Gerisch B, Kawamura K, Laboy R, Hewitt J, Denzel MS, Mori MA, Vanapalli S, Shen Y, Symmons O, Antebi A (2021). miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to affect muscle contractility upon proteotoxic challenge during ageing. biorxiv. doi: https://doi.org/10.1101/2021.01.21.427623
  • Allmeroth K, Horn M, Kroef V, Miethe S, Müller RU, Denzel MS (2021). Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma. Leukemia.2021 Mar;35(3):887-892. doi: 10.1038/s41375-020-0989-4. Epub 2020 Jul 20. PMID: 32690882 
  • Allmeroth K, Kim CS, Annibal A, Pouikli A, Koester J, Derisbourg MJ, Andrés Chacón-Martínez C, Latza C, Antebi A,Tessarz P, Wickström SA, Denzel MS. N1-acetylspermidine is a determinant of hair follicle stem cell fate. J Cell Sci. 2021 May 1;134(9):jcs252767. doi: 10.1242/jcs.252767. Epub 2021 May 11. PMID: 33973637.

Sabine Eming

  • Ding X, Kakanj P, Leptin M, Eming SA (2021).. Regulation of the wound healing response during aging. J Invest Dermatol. 2021 Feb 5;S0022-202X(20)32360-5. doi: 10.1016/j.jid.2020.11.014. Online ahead of print 
  • Hadrian K, Willenborg S, Bock F, Cursiefen C, Eming SA, Hos D. Macrophage-Mediated Tissue Vascularization: Similarities and Differences Between Cornea and Skin. Front Immunol. 2021 Apr 7;12:667830. doi: 10.3389/fimmu.2021.667830. PMID: 33897716; PMCID: PMC8058454.

Lukas P. Frenzel

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798

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Henning Fenselau

  • Bozadjieva-Kramer N, Ross RA, Johnson DQ, Fenselau H, Haggerty DL, Atwood B, Lowell B, Flak JN (2021). The Role of Mediobasal Hypothalamic PACAP in the Control of Body Weight and Metabolism. Endocrinology. 2021 Jan 18:bqab012. doi: 10.1210/endocr/bqab012. Online ahead of print. PMID: 33460433.
  • Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC (2021). Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat Neurosci. 2021 May 17. doi: 10.1038/s41593-021-00854-0. Epub ahead of print. PMID: 34002087.
  • Borgmann D, Ciglieri E, Biglari N, Brandt C, Cremer AL, Backes H, Tittgemeyer M, Wunderlich FT, Brüning JC, Fenselau H (2021). Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metab. 2021 May 21:S1550-4131(21)00219-9. doi: 10.1016/j.cmet.2021.05.002. Epub ahead of print. PMID: 34043943.

 

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Ana J. Garcia-Saez

  • Dadsena S, Jenner A, García-Sáez AJ (2021). Mitochondrial outer membrane permeabilization at the single molecule level. Cell Mol Life Sci. 2021 Feb 12. doi: 10.1007/s00018-021-03771-4. Online ahead of print. PMID: 33576840 Review
  • Ros U, Pedrera L, Garcia-Saez AJ (2021). Techniques for studying membrane pores. Curr Opin Struct Biol. 2021 May 1;69:108-116. doi: 10.1016/j.sbi.2021.03.012. Epub ahead of print. PMID: 33945958
  • Danial JSH, Shalaby R, Cosentino K, Mahmoud MM, Medhat F, Klenerman D, Garcia Saez AJ (2021). DeepSinse: deep learning based detection of single molecules. Bioinformatics. 2021 May 8:btab352. doi: 10.1093/bioinformatics/btab352. Online ahead of print. PMID: 33964131

Michael Hallek

  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798
  • Pan H, Renaud L, Chaligne R, Bloehdorn J, Tausch E, Mertens D, Fink AM, Fischer K, Zhang C, Betel D, Gnirke A, Imielinski M, Moreaux J, Hallek M, Meissner A, Stilgenbauer S, Wu CJ, Elemento O, Landau DA. Discovery of candidate DNA methylation cancer driver genes. Cancer Discov. 2021 May 10:candisc.1334.2020. doi: 10.1158/2159-8290.CD-20-1334. Epub ahead of print. PMID: 33972312. 
  • Augustin M, Schommers P, Stecher M, Dewald F, Gieselmann L, Gruell H, Horn C, Vanshylla K, Cristanziano VD, Osebold L, Roventa M, Riaz T, Tschernoster N, Altmueller J, Rose L, Salomon S, Priesner V, Luers JC, Albus C, Rosenkranz S, Gathof B, Fätkenheuer G, Hallek M, Klein F, Suárez I, Lehmann C (2021). Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study. Lancet Reg Health Eur. 2021 Jul;6:100122. doi: 10.1016/j.lanepe.2021.100122. Epub 2021 May 18. PMID: 34027514; PMCID: PMC8129613.

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Marco Herling

  • Böttcher M, Bruns H, Völkl S, Lu J, Chartomatsidou E, Papakonstantinou N, Mentz K, Büttner-Herold M, Zenz T, Herling M, Huber W, Ghia P, Stamatopoulos K, Mackensen A, Mougiakakos D. Control of PD-L1 expression in CLL-cells by stromal triggering of the Notch-c-Myc-EZH2 oncogenic signaling axis. J Immunother Cancer. 2021 Apr;9(4):e001889. doi: 10.1136/jitc-2020-001889. PMID: 33931470. 
  • Wahnschaffe L, Herling M (2021). Hijacking the Pathway: Perspectives in the Treatment of Mature T-cell Leukemias. Hemasphere.2021 Jun 1;5(6):e573. doi: 10.1097/HS9.0000000000000573. PMID: 34095757; PMCID: PMC8171373.

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Jan Hoeijmakers

  • Birkisdóttir MB, Jaarsma D, Brandt RMC, Barnhoorn S, van Vliet N, Imholz S, van Oostrom CT, Nagarajah B, Portilla Fernández E, Roks AJM, Elgersma Y, van Steeg H, Ferreira JA, Pennings JLA, Hoeijmakers JHJ, Vermeij WP, Dollé MET (2021). Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice. Aging Cell. 2021 Jan 23:e13302. doi: 10.1111/acel.13302. Online ahead of print.PMID: 33484480
  • Botta E, Theil AF, Raams A, Caligiuri G, Giachetti S, Bione S, Accadia M, Lombardi A, Smith DEC, Mendes MI, Swagemakers SMA, van der Spek PJ, Salomons GS, Hoeijmakers JHJ, Yesodharan D, Nampoothiri S, Ogi T, Lehmann AR, Orioli D, Vermeulen W. Protein instability associated with AARS1 and MARS1 mutations causes Trichothiodystrophy. Hum Mol Genet. 2021 Apr 28:ddab123. doi: 10.1093/hmg/ddab123. Epub ahead of print. PMID: 33909043. Van't Sant LJ, White JJ, Hoeijmakers JHJ, Vermeij WP, Jaarsma D (2021).
  • In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration. Acta Neuropathol Commun. 2021 May 21;9(1):94. doi: 10.1186/s40478-021-01200-y. PMID: 34020718; PMCID: PMC8139001.

Thorsten Hoppe    

  • Ottens F, Franz A, Hoppe T (2021). Build-UPS and break-downs: metabolism impacts on proteostasis and aging. Cell Death Differ. 2021 Jan 4. doi: 10.1038/s41418-020-00682-y. Online ahead of print. PMID: 33398091 Review 
  • Müller L, Kutzner CE, Balaji V, Hoppe T (2021). In Vitro Analysis of E3 Ubiquitin Ligase Function. J Vis Exp. 2021 May 14;(171). doi: 10.3791/62393. PMID: 34057440.

Pitter Huesgen

  • Passarge A, Demir F, Green K, Depotter JRL, Scott B, Huesgen PF, Doehlemann G, Misas Villamil JC (2021). Host apoplastic cysteine protease activity is supressed during the mutualistic association of Lolium perenne and Epichloë festucae. J Exp Bot. 2021 Feb 25:erab088. doi: 10.1093/jxb/erab088. Online ahead of print. PMID: 33630999 
  • Mooney BC, Mantz M, Graciet E, Huesgen PF (2021). Cutting the line: manipulation of plant immunity by bacterial type III effector proteases. J Exp Bot. 2021 Feb 26:erab095. doi: 10.1093/jxb/erab095. Online ahead of print. PMID: 33640987
  • Demir F, Kizhakkedathu JN, Rinschen MM, Huesgen PF (2021). MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets. Anal Chem. 2021 Mar 17. doi: 10.1021/acs.analchem.1c00310. Online ahead of print. PMID: 33729755 
  • Hofsetz E., Huesgen P.F.,Trifunovic A.(2021) Identification of Putative Mitochondrial Protease Substrates. In: Minczuk M., Rorbach J.. Mitochondrial Gene Expression. Methods in Molecular Biology, vol 2192. Humana, New York, NY. doi: 10.1007/978-1-0716-0834-0_21. 
  • Demir F, Troldborg A, Thiel S, Lassé M, Huesgen PF, Tomas NM, Wiech T, Rinschen MM. Proteolysis and inflammation of the kidney glomerulus. Cell Tissue Res. 2021 Apr 17:1–12. doi: 10.1007/s00441-021-03433-8. Epub ahead of print. PMID: 33864499; PMCID: PMC8052535. 
  • Drexelius M, Reinhardt A, Grabeck J, Cronenberg T, Nitsche F, Huesgen PF, Maier B, Neundorf I. Multistep optimization of a cell-penetrating peptide towards its antimicrobial activity. Biochem J. 2021 Jan 15;478(1):63-78. doi: 10.1042/BCJ20200698. PMID: 33313751.

Sandra Iden 

  • Li M, Iden S (2021) Emerging Laminin-332‒Dependent and ‒Independent Roles for Integrin α3 in Protumorigenic Signaling. J Invest Dermatol. 2021 Apr;141(4):713-716. doi: 10.1016/j.jid.2020.08.017. PMID: 33752808

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Frank Jessen

  • Sannemann L, Müller T, Waterink L, Zwan M, Wimo A, Stomrud E, Pinó S, Arrufat J, Rodríguez-Gomez O, Benaque A, Bon J, Ferreira D, Johansson G, Dron A, Dumas A, Georges J, Kramberger MG, Visser PJ, Winblad B, Campo L, Boada M, Jessen F; MOPEAD consortium (2021). General practitioners' attitude toward early and pre-dementia diagnosis of AD in five European countries-A MOPEAD project survey.  Alzheimers Dement (Amst). 2021 Feb 23;13(1):e12130. doi: 10.1002/dad2.12130. eCollection 2021. PMID: 33665337  
  • Marchant NL, Barnhofer T, Coueron R, Wirth M, Lutz A, Arenaza-Urquijo EM, Collette F, Poisnel G, Demnitz-King H, Schild AK, Coll-Padros N, Delphin-Combe F, Whitfield T, Schlosser M, Gonneaud J, Asselineau J, Walker Z, Krolak-Salmon P, Molinuevo JL, Frison E, Chételat G, Jessen F, Klimecki OM; The Medit-Ageing Research Group. Effects of a Mindfulness-Based Intervention versus Health Self-Management on Subclinical Anxiety in Older Adults with Subjective Cognitive Decline: The SCD-Well Randomized Superiority Trial. Psychother Psychosom. 2021 Apr 19:1-10. doi: 10.1159/000515669. Epub ahead of print. PMID: 33873195. 
  • Hammes J, Bischof GN, Bohn KP, Onur Ö, Schneider A, Fliessbach K, Hönig MC, Jessen F, Neumaier B, Drzezga A, van Eimeren T (2021). One-Stop Shop: 18F-Flortaucipir PET Differentiates Amyloid-Positive and -Negative Forms of Neurodegenerative Diseases. J Nucl Med. 2021 Feb;62(2):240-246. doi: 10.2967/jnumed.120.244061. Epub 2020 Jul 3. PMID: 32620704.
  • Ballarini T, Melo van Lent D, Brunner J, Schröder A, Wolfsgruber S, Altenstein S, Brosseron F, Buerger K, Dechent P, Dobisch L, Duzel E, Ertl-Wagner B, Fliessbach K, Freiesleben SD, Frommann I, Glanz W, Hauser D, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk M, Perneczky R, Peters O, Priller J, Ramirez A, Rauchmann B, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel SJ, Vukovich R, Wiltfang J, Jessen F, Wagner M; DELCODE study group. Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age. Neurology. 2021 May 5:10.1212/WNL.0000000000012067. doi: 10.1212/WNL.0000000000012067. Epub ahead of print. PMID: 33952652.
  • Hansen N, Singh A, Bartels C, Brosseron F, Buerger K, Cetindag AC, Dobisch L, Dechent P, Ertl-Wagner BB, Fliessbach K, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Vukovich R, Wiltfang J, Duezel E, Jessen F, Goya-Maldonado R. Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline. Front Aging Neurosci. 2021 Apr 21;13:626974. doi: 10.3389/fnagi.2021.626974. PMID: 33967736; PMCID: PMC8097178. 
  • Rauchmann BS, Ersoezlue E, Stoecklein S, Keeser D, Brosseron F, Buerger K, Dechent P, Dobisch L, Ertl-Wagner B, Fliessbach K, Haynes JD, Heneka MT, Incesoy EI, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Vukovich R, Wagner M, Wiltfang J, Yakupov R, Duezel E, Jessen F, Perneczky R; DELCODE study group and the Alzheimer's Disease Neuroimaging Initiative (ADNI) (2021). Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes. Cereb Cortex. 2021 Jun 3:bhab130. doi: 10.1093/cercor/bhab130. Epub ahead of print. PMID: 34080613.

Hamid Kashkar      

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • He L, Sehrawat TS, Verma VK, Navarro-Corcuera A, Sidhu G, Mauer A, Luo X, Katsumi T, Chen J, Shah S, Arab JP, Cao S, Kashkar H, Gores GJ, Malhi H, Shah VH (2021). XIAP Knockdown in Alcohol-Associated Liver Disease Models Exhibits Divergent in vitro and in vivoPhenotypes Owing to a Potential Zonal Inhibitory Role of SMAC. Front Physiol. 2021 May 7;12:664222. doi: 10.3389/fphys.2021.664222. PMID: 34025452; PMCID: PMC8138467.

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Peter Kloppenburg

  • Fuscà D, Kloppenburg P (2021). Odor processing in the cockroach antennal lobe-the network components. Cell Tissue Res. 2021 Jan 23. doi: 10.1007/s00441-020-03387-3. Online ahead of print. PMID: 33486607 Review. 
  • Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC (2021). Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat Neurosci. 2021 May 17. doi: 10.1038/s41593-021-00854-0. Epub ahead of print. PMID: 34002087. 
  • Hess S, Pouzat C, Paeger L, Pippow A, Kloppenburg P (2021). Analysis of neuronal Ca2+handling properties by combining perforated patch clamp recordings and the added buffer approach. Cell Calcium. 2021 May 10;97:102411. doi: 10.1016/j.ceca.2021.102411. Epub ahead of print. PMID: 34082340.

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Natalia Kononenko

  • Negrete-Hurtado A, Overhoff M, Bera S, De Bruyckere E, Schätzmüller K, Kye MJ, Qin C, Lammers M, Kondylis V, Neundorf I, Kononenko N (2020). Autophagy lipidation machinery regulates axonal microtubule dynamics but is dispensable for survival of mammalian neurons. Nat Commun. 2020; 11: 1535. Published online 2020 Mar 24. doi: 10.1038/s41467-020-15287-9  
  • Overhoff M, De Bruyckere E, Kononenko NL (2020). Mechanisms of neuronal survival safeguarded by endocytosis and autophagy. J Neurochem. 2020 Sep 22. doi: 10.1111/jnc.15194. Online ahead of print. PMID: 32964462
  • Camblor-Perujo S, Kononenko NL. Brain-specific functions of the endocytic machinery. FEBS J. 2021 Apr 25. doi: 10.1111/febs.15897. Epub ahead of print. PMID: 33896112.

Thomas Krieg

  • Schumacher B, Krieg TM (2021). The Aging Skin: From Basic Mechanisms to Clinical Applications. J Invest Dermatol. 2021 Apr;141(4S):949-950. doi: 10.1016/j.jid.2020.12.002. PMID: 33752815

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Martin Krönke

  • Klimka A, Mertins S, Nicolai AK, Rummler LM, Higgins PG, Günther SD, Tosetti B, Krut O, Krönke M (2021). Epitope-specific immunity against Staphylococcus aureus coproporphyrinogen III oxidase. NPJ Vaccines. 2021 Jan 18;6(1):11. doi: 10.1038/s41541-020-00268-2. PMID: 33462229 
  • Tosetti B, Ward B, Grumme D, Herb M, Schramm M, Utermöhlen O, Heukamp LC, Krönke M, Krut O. NOX2 Deficiency Permits Sustained Survival of S. aureus in Macrophages and Contributes to Severity of Infection. Front Immunol. 2021 Mar 22;12:633629. doi: 10.3389/fimmu.2021.633629. PMID: 33868252; PMCID: PMC8044967.

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Marcus Krüger

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • Ianni A, Kumari P, Tarighi S, Simonet NG, Popescu D, Guenther S, Hölper S, Schmidt A, Smolka C, Yue S, Krüger M, Fiorillo C, Vaquero A, Bober E, Braun T (2021). SIRT7-dependent deacetylation of NPM promotes p53 stabilization following UV-induced genotoxic stress. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2015339118. doi: 10.1073/pnas.2015339118. PMID: 33495326  
  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798
  • Abdellatif M, Trummer-Herbst V, Koser F, Durand S, Adão R, Vasques-Nóvoa F, Freundt JK, Voglhuber J, Pricolo MR, Kasa M, Türk C, Aprahamian F, Herrero-Galán E, Hofer SJ, Pendl T, Rech L, Kargl J, Anto-Michel N, Ljubojevic-Holzer S, Schipke J, Brandenberger C, Auer M, Schreiber R, Koyani CN, Heinemann A, Zirlik A, Schmidt A, von Lewinski D, Scherr D, Rainer PP, von Maltzahn J, Mühlfeld C, Krüger M, Frank S, Madeo F, Eisenberg T, Prokesch A, Leite-Moreira AF, Lourenço AP, Alegre-Cebollada J, Kiechl S, Linke WA, Kroemer G, Sedej S (2021). Nicotinamide for the treatment of heart failure with preserved ejection fraction. Sci Transl Med. 2021 Feb 10;13(580):eabd7064. doi: 10.1126/scitranslmed.abd7064
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. 2021 Feb 5;154:41-59. doi: 10.1016/j.yjmcc.2021.01.010. Online ahead of print.

Leo Kurian

  • Kargapolova Y, Rehimi R, Kayserili H, Brühl J, Sofiadis K, Zirkel A, Palikyras S, Mizi A, Li Y, Yigit G, Hoischen A, Frank S, Russ N, Trautwein J, van Bon B, Gilissen C, Laugsch M, Gusmao EG, Josipovic N, Altmüller J, Nürnberg P, Längst G, Kaiser FJ, Watrin E, Brunner H, Rada-Iglesias A, Kurian L, Wollnik B, Bouazoune K, Papantonis A (2021). Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology. Nat Commun. 2021 May 21;12(1):3014. doi: 10.1038/s41467-021-23327-1. PMID: 34021162; PMCID: PMC8140133.

Thomas Langer

  • Eiyama A, Aaltonen MJ, Nolte H, Tatsuta T, Langer T (2021). Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling. J Biol Chem. 2021 Jan 23:100335. doi: 10.1016/j.jbc.2021.100335. PMID: 33497623 
  • Sprenger HG, MacVicar T, Bahat A, Fiedler KU, Hermans S, Ehrentraut D, Ried K, Milenkovic D, Bonekamp N, Larsson NG, Nolte H, Giavalisco P, Langer T (2021). Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity. Nat Metab. 2021 Apr 26. doi: 10.1038/s42255-021-00385-9. Epub ahead of print. PMID: 33903774. 
  • Nolte H, Langer T. ComplexFinder: A software package for the analysis of native protein complex fractionation experiments. Biochim Biophys Acta Bioenerg. 2021 Apr 30:148444. doi: 10.1016/j.bbabio.2021.148444. Epub ahead of print. PMID: 33940038. 
  • Cretin E, Lopes P, Vimont E, Tatsuta T, Langer T, Gazi A, Sachse M, Yu-Wai-Man P, Reynier P, Wai T (2021).High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts. EMBO Mol Med. 2021 May 20:e13579. doi: 10.15252/emmm.202013579. Epub ahead of print. PMID: 34014035.

Maria Leptin

  • Ding X, Kakanj P, Leptin M, Eming SA (2021). Regulation of the Wound Healing Response during Aging. J Invest Dermatol. 2021 Feb 5;S0022-202X(20)32360-5. doi: 10.1016/j.jid.2020.11.014. Online ahead of print.

Roman-Ulrich Müller

  • Allmeroth K, Horn M, Kroef V, Miethe S, Müller RU, Denzel MS (2021). Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma. Leukemia.2021 Mar;35(3):887-892. doi: 10.1038/s41375-020-0989-4. Epub 2020 Jul 20. PMID: 32690882 
  • Talyan S, Filipów S, Ignarski M, Smieszek M, Chen H, Kühne L, Butt L, Göbel H, Hoyer-Allo KJR, Koehler FC, Altmüller J, Brinkkötter P, Schermer B, Benzing T, Kann M, Müller RU, Dieterich C. CALINCA-A Novel Pipeline for the Identification of lncRNAs in Podocyte Disease. Cells. 2021 Mar 20;10(3):692. doi: 10.3390/cells10030692. PMID: 33804736; PMCID: PMC8003990. 
  • Hoyer-Allo KJR, Späth MR, Hanssen R, Johnsen M, Brodesser S, Kaufmann K, Kiefer K, Koehler FC, Göbel H, Kubacki T, Grundmann F, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2021). Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury. Int J Mol Sci. 2021 May 22;22(11):5485. doi: 10.3390/ijms22115485. PMID: 34067475; PMCID: PMC8196977.

Carien Niessen

  • Persa OD, Koester J, Niessen CM (2021). Regulation of Cell Polarity and Tissue Architecture in Epidermal Aging and Cancer. J Invest Dermatol. 2021 Jan 30:S0022-202X(20)32410-6. doi: 10.1016/j.jid.2020.12.012. Online ahead of print. PMID: 33531135 
  • Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernández-Baldovinos J, Zhou L, Höß C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Gröne HJ, Graumann PL, Niessen CM, Offermanns S, Wickström SA, Worzfeld T (2021). Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308. doi: 10.1038/s41467-021-21513-9. PMID: 33637728 
  • Tayem R, Niemann C, Pesch M, Morgner J, Niessen CM, Wickström SA, Aumailley M (2021). LAMININ 332 IS INDISPENSABLE FOR HOMEOSTATIC EPIDERMAL DIFFERENTIATION PROGRAMS. J Invest Dermatol. 2021 May 6:S0022-202X(21)01215-X. doi: 10.1016/j.jid.2021.04.008. Epub ahead of print. PMID: 33965403.

Linda Partridge

  • Fuentealba M, Fabian DK, Dönertaş HM, Thornton JM, Partridge L (2021). Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice. Mech Ageing Dev. 2021 Mar;194:111437. doi: 10.1016/j.mad.2021.111437. Epub 2021 Jan 14. PMID: 33454277
  • Bolukbasi E, Woodling NS, Ivanov DK, Adcott J, Foley A, Rajasingam A, Gittings LM, Aleyakpo B, Niccoli T, Thornton JM, Partridge L (2021). Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2011491118. doi: 10.1073/pnas.2011491118. PMID: 33593901
  • Fabian DK, Melike Dönertaş H, Fuentealba M, Partridge L, Thornton JM (2021). Transposable element landscape in Drosophila populations selected for longevity. Genome Biol Evol. 2021 Feb 17:evab031. doi: 10.1093/gbe/evab031. Online ahead of print. PMID: 33595657
  • Kuan V, Fraser HC, Hingorani M, Denaxas S, Gonzalez-Izquierdo A, Direk K, Nitsch D, Mathur R, Parisinos CA, Lumbers RT, Sofat R, Wong ICK, Casas JP, Thornton JM, Hemingway H, Partridge L, Hingorani AD (2021). Data-driven identification of ageing-related diseases from electronic health records. Sci Rep. 2021 Feb 3;11(1):2938. doi: 10.1038/s41598-021-82459-y. PMID: 33536532 
  • Tain LS, Sehlke R, Meilenbrock RL, Leech T, Paulitz J, Chokkalingam M, Nagaraj N, Grönke S, Fröhlich J, Atanassov I, Mann M, Beyer A, Partridge L. Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila. Elife. 2021 Apr 21;10:e67275. doi: 10.7554/eLife.67275. PMID: 33879316; PMCID: PMC8060030.

Manolis Pasparakis  

  • Kumari S, Van TM, Preukschat D, Schuenke H, Basic M, Bleich A, Klein U, Pasparakis M (2021).NF-κB inhibition in keratinocytes causes RIPK1-mediated necroptosis and skin inflammation. Life Sci Alliance. 2021 Apr 15;4(6):e202000956. doi: 10.26508/lsa.202000956. PMID: 33858959. 
  • Oikonomou N, Schuijs MJ, Chatzigiagkos A, Androulidaki A, Aidinis V, Hammad H, Lambrecht BN, Pasparakis M(2021). Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation. Mucosal Immunol. 2021 May 27. doi: 10.1038/s41385-021-00415-5. Epub ahead of print. PMID: 34045680.

Lena Pernas

  • Pernas L (2021). Cellular Metabolism in the Defense Against Microbes. J Cell Science. 134(5)jcs252023. doi: 10.1242/jcs.252023.PMID: 33558420.

Dominik Pesta

  • Strasser B, Pesta D, Rittweger J, Burtscher J, Burtscher M (2021). Nutrition for Older Athletes: Focus on Sex-Differences. Nutrients. 2021 Apr 22;13(5):1409. doi: 10.3390/nu13051409. PMID: 33922108; PMCID: PMC8143537.

Christina Polidori

  • Pickert L, Meyer AM, Becker I, Heeß A, Noetzel N, Brinkkötter P, Pilotto A, Benzing T, Polidori MC (2021). Role of a multidimensional prognosis in-hospital monitoring for older patients with prolonged stay. Int J Clin Pract. 2021 Jan 6:e13989. doi: 10.1111/ijcp.13989. Online ahead of print. PMID: 33406298
  • Polidori MC, Sies H, Ferrucci L, Benzing T(2021). COVID-19 mortality as a fingerprint of biological age. Ageing Res Rev. 2021 May;67:101308. doi: 10.1016/j.arr.2021.101308. Epub 2021 Feb 20. PMID: 33621704; PMCID: PMC7896489
  • Meyer AM, Wiebe L, Faust M, Chiapponi C, Brinkkoetter PT, Polidori MC, Bartram MP (2021). Cognitive disorder, depression and gait disturbance in an internal medicine patient-geriatric syndromes in an acute care hospital. Z Gerontol Geriatr. 2021 Feb;54(1):77-80. doi: 10.1007/s00391-020-01811-5. Epub 2020 Nov 13.
  • Kasdorf A, Dust G, Vennedey V, Rietz C, Polidori MC, Voltz R, Strupp J, CoRe Net (2021). What are the risk factors for avoidable transitions in the last year of life? A qualitative exploration of professionals' perspectives for improving care in Germany. BMC Health Serv Res. 2021 Feb 15;21(1):147. doi: 10.1186/s12913-021-06138-4. PMID: 33588851; PMCID: PMC7885553. 
  • Polidori MC, Stahl W, Griffiths HR (2021). Nutritional cognitive neuroscience of aging: Focus on carotenoids and cognitive frailty. Redox Biol. 2021 Aug;44:101996. doi: 10.1016/j.redox.2021.101996. Epub 2021 May 8. PMID: 34090844.

Simon Pöpsel

  • Kasinath V, Beck C, Sauer P, Poepsel S, Kosmatka J, Faini M, Toso D, Aebersold R, Nogales E (2021). JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. Science. 2021 Jan 22;371(6527):eabc3393. doi: 10.1126/science.abc3393. PMID: 33479123 
  • Finogenova K, Bonnet J, Poepsel S, Schäfer IB, Finkl K, Schmid K, Litz C, Strauss M, Benda C, Müller J. Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3. Elife. 2020 Nov 19;9:e61964. doi: 10.7554/eLife.61964. PMID: 33211010; PMCID: PMC7725500.

Alvaro Rada-Iglesias

  • Thues C, Valadas JS, Deaulmerie L, Geens A, Chouhan AK, Duran-Romaña R, Schymkowitz J, Rousseau F, Bartusel M, Rehimi R, Rada-Iglesias A, Verstreken P, Van Esch H (2021). MAPRE2 mutations result in altered human cranial neural crest migration, underlying craniofacial malformations in CSC-KT syndrome. Sci Rep. 2021 Mar 2;11(1):4976. doi: 10.1038/s41598-021-83771-3. PMID: 33654163 
  • Kargapolova Y, Rehimi R, Kayserili H, Brühl J, Sofiadis K, Zirkel A, Palikyras S, Mizi A, Li Y, Yigit G, Hoischen A, Frank S, Russ N, Trautwein J, van Bon B, Gilissen C, Laugsch M, Gusmao EG, Josipovic N, Altmüller J, Nürnberg P, Längst G, Kaiser FJ, Watrin E, Brunner H, Rada-Iglesias A, Kurian L, Wollnik B, Bouazoune K, Papantonis A (2021). Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology. Nat Commun. 2021 May 21;12(1):3014. doi: 10.1038/s41467-021-23327-1. PMID: 34021162; PMCID: PMC8140133.

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Hans Christian Reinhardt

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • Lennartz S, Mager A, Große Hokamp N, Schäfer S, Zopfs D, Maintz D, Reinhardt HC, Thomas RK, Caldeira L, Persigehl T (2021). Texture analysis of iodine maps and conventional images for k-nearest neighbor classification of benign and metastatic lung nodules. Cancer Imaging. 2021 Jan 26;21(1):17. doi: 10.1186/s40644-020-00374-3. PMID: 33499939 
  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798 
  • Klein S, Quaas A, Quantius J, Löser H, Meinel J, Peifer M, Wagner S, Gattenlöhner S, Wittekindt C, Doeberitz MVK, Prigge ES, Langer C, Noh KW, Maltseva M, Reinhardt HC, Büttner R, Klussmann JP, Wuerdemann N (2021). Deep Learning Predicts HPV Association in Oropharyngeal Squamous Cell Carcinomas and Identifies Patients with a Favorable Prognosis Using Regular H&E Stains. Clin Cancer Res. 2021 Feb 15;27(4):1131-1138.  doi: 10.1158/1078-0432.CCR-20-3596. Epub 2020 Dec 1
  • Bebber CM, Thomas ES, Stroh J, Chen Z, Androulidaki A, Schmitt A, Höhne MN, Stüker L, de Pádua Alves C, Khonsari A, Dammert MA, Parmaksiz F, Tumbrink HL, Beleggia F, Sos ML, Riemer J,  George J, Brodesser S, Thomas RK, Reinhardt HC, von Karstedt S (2021). Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nat Commun. 2021 Apr 6;12(1):2048. doi: 10.1038/s41467-021-22336-4

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Jan Riemer

  • Peker E, Erdogan AJ, Volkov AN, Riemer J (2021). Erv1 and Cytochrome c Mediate Rapid Electron Transfer via A Collision-Type Interaction. J Mol Biol. 2021 May 8;433(15):167045. doi: 10.1016/j.jmb.2021.167045. Epub ahead of print. PMID: 33971209.

Elena Rugarli

  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. 2021 Feb 5;154:41-59.  doi: 10.1016/j.yjmcc.2021.01.010. Online ahead of print.

Bernhard Schermer

  • Fabretti F, Tschernoster N, Erger F, Hedergott A, Buescher AK, Dafinger C, Reusch B, Köntges VK, Kohl S, Bartram MP, Weber LT, Thiele H, Altmueller J, Schermer B, Beck BB, Habbig S (2021). Expanding the Spectrum of FAT1 Nephropathies by Novel Mutations That Affect Hippo Signaling. Kidney Int Rep. 2021 Jan 29;6(5):1368-1378. doi: 10.1016/j.ekir.2021.01.023. PMID: 34013115; PMCID: PMC8116753.
  • Hoyer-Allo KJR, Späth MR, Hanssen R, Johnsen M, Brodesser S, Kaufmann K, Kiefer K, Koehler FC, Göbel H, Kubacki T, Grundmann F, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2021). Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury. Int J Mol Sci. 2021 May 22;22(11):5485. doi: 10.3390/ijms22115485. PMID: 34067475; PMCID: PMC8196977.

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Björn Schumacher

  • da Silva PFL, Schumacher B (2021). Principles of the Molecular and Cellular Mechanisms of Aging. J Invest Dermatol. 2021 Jan 28:S0022-202X(20)32364-2. doi: 10.1016/j.jid.2020.11.018. Online ahead of print. PMID: 33518357 
  • Meyer DH, Schumacher B (2021). BiT age: A transcriptome‐based aging clock near the theoretical limit of accuracy. Aging Cell. 2021 Mar;20(3):e13320. doi: 10.1111/acel.13320. Epub 2021 Mar 3
  • Schumacher B, Krieg TM (2021). The Aging Skin: From Basic Mechanisms to Clinical Applications. J Invest Dermatol. 2021 Apr;141(4S):949-950. doi: 10.1016/j.jid.2020.12.002. PMID: 33752815 
  • Schumacher B, Pothof J, Vijg J, Hoeijmakers JHJ (2021). The central role of DNA damage in the ageing process. Nature. 2021 Apr;592(7856):695-703. doi: 10.1038/s41586-021-03307-7. Epub 2021 Apr 28. PMID: 33911272.
  • Ou HL, Schumacher B (2021). Evaluating DNA damage response through immunofluorescence staining of primordial germ cells in Caenorhabditis elegans L1 larva. STAR Protoc. 2021 Apr 5;2(2):100441. doi: 10.1016/j.xpro.2021.100441. PMID: 33899022; PMCID: PMC8056264.

Peter Tessarz

  • Pouikli A, Tessarz P (2021). Epigenetic alterations in stem cell ageing-a promising target for age-reversing interventions?. Brief Funct Genomics. 2021 Mar 19:elab010. doi: 10.1093/bfgp/elab010. Online ahead of print. PMID: 33738480 
  • Pouikli A, Tessarz P (2021). Metabolism and chromatin: A dynamic duo that regulates development and ageing: Elucidating the metabolism-chromatin axis in bone-marrow mesenchymal stem cell fate decisions. Bioessays. 2021 Feb 25:e2000273. doi: 10.1002/bies.202000273. Online ahead of print. PMID: 33629755 
  • Allmeroth K, Kim CS, Annibal A, Pouikli A, Koester J, Derisbourg MJ, Andrés Chacón-Martínez C, Latza C, Antebi A,Tessarz P, Wickström SA, Denzel MS. N1-acetylspermidine is a determinant of hair follicle stem cell fate. J Cell Sci. 2021 May 1;134(9):jcs252767. doi: 10.1242/jcs.252767. Epub 2021 May 11. PMID: 33973637.

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Marc Tittgemeyer

  • Ruppert MC, Greuel A, Freigang J, Tahmasian M, Maier F, Hammes J, van Eimeren T, Timmermann L, Tittgemeyer M, Drzezga A, Eggers C (2021).  The default mode network and cognition in Parkinson's disease: A multimodal resting-state network approach. Hum Brain Mapp. 2021 Feb 27. doi: 10.1002/hbm.25393. Online ahead of print. PMID: 33638213
  • Schöbi D, Homberg F, Frässle S, Endepols H, Moran RJ, Friston KJ, Tittgemeyer M, Heinzle J, Stephan KE. Model-based prediction of muscarinic receptor function from auditory mismatch negativity responses. Neuroimage. 2021 Apr 30:118096. doi: 10.1016/j.neuroimage.2021.118096. Epub ahead of print. PMID: 33940149.
  • Borgmann D, Ciglieri E, Biglari N, Brandt C, Cremer AL, Backes H, Tittgemeyer M, Wunderlich FT, Brüning JC, Fenselau H (2021). Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metab. 2021 May 21:S1550-4131(21)00219-9. doi: 10.1016/j.cmet.2021.05.002. Epub ahead of print. PMID: 34043943.

Alexandra Trifunovic

  • Hofsetz E, Huesgen PF, Trifunovic A (2021). Identification of Putative Mitochondrial Protease Substrates. Methods Mol Biol. 2021;2192:313-329. doi: 10.1007/978-1-0716-0834-0_21. PMID: 33230781 
  • Szczepanowska K, Trifunovic A (2021). Tune instead of destroy: How proteolysis keeps OXPHOS in shape. Biochim Biophys Acta Bioenerg. 2021 Jan 5:148365. doi: 10.1016/j.bbabio.2020.148365. Online ahead of print. PMID: 33417924 Review 
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. 2021 Feb 4:S0022-2828(21)00025-0.PMID: 33549681
  • Silva-Pinheiro P, Pardo-Hernández C, Reyes A, Tilokani L, Mishra A, Cerutti R, Li S, Rozsivalova DH, Valenzuela S, Dogan SA, Peter B, Fernández-Silva P, Trifunovic A, Prudent J, Minczuk M, Bindoff L, Macao B, Zeviani M, Falkenberg M, Viscomi C. DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion. Nucleic Acids Res. 2021 May 6:gkab282. doi: 10.1093/nar/gkab282. Epub ahead of print. PMID: 33956154. 
  • Kaspar S, Oertlin C, Szczepanowska K, Kukat A, Senft K, Lucas C, Brodesser S, Hatzoglou M, Larsson O, Topisirovic I, Trifunovic A (2021). Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR. Sci Adv. 2021 May 26;7(22):eabf0971. doi: 10.1126/sciadv.abf0971. PMID: 34039602.

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Achim Tresch

  • Failmezger H, Zwing N, Tresch A, Korski K, Schmich F. Computational Tumor Infiltration Phenotypes Enable the Spatial and Genomic Analysis of Immune Infiltration in Colorectal Cancer. Front Oncol. 2021 Mar 15;11:552331. doi: 10.3389/fonc.2021.552331. PMID: 33791196; PMCID: PMC8006941.

 

Mirka Uhlirova

  • Erkelenz S, Stankovic D, Mundorf J, Bresser T, Claudius A-K, Boehm V, Gehring NH, Uhlirova M (2021). Ecd promotes U5 snRNP maturation and Prp8 stability. Nucleic Acids Res. gkaa1274

Dario Valenzano

  • Cui R, Tyers AM, Malubhoy ZJ, Wisotsky S, Valdesalici S, Henriette E, Kosakovsky Pond SL, Valenzano DR(2021). Ancestral transoceanic colonization and recent population reduction in a non-annual killifish from the Seychelles archipelago. Mol Ecol. 2021 May 16. doi: 10.1111/mec.15982. Epub ahead of print. PMID: 33998095.

Silvia von Karstedt

  • Bebber CM, Thomas ES, Stroh J, Chen Z, Androulidaki A, Schmitt A, Höhne MN, Stüker L, de Pádua Alves C, Khonsari A, Dammert MA, Parmaksiz F, Tumbrink HL, Beleggia F, Sos ML, Riemer J,  George J, Brodesser S, Thomas RK, Reinhardt C, von Karstedt S (2021). Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nat Commun. 2021 Apr 6;12(1):2048. doi: 10.1038/s41467-021-22336-4

Sara Wickström

  • Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernández-Baldovinos J, Zhou L, Höß C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Gröne HJ, Graumann PL, Niessen CM, Offermanns S, Wickström SA, Worzfeld T (2021). Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308. doi: 10.1038/s41467-021-21513-9. PMID: 33637728
  • Allmeroth K, Kim CS, Annibal A, Pouikli A, Koester J, Derisbourg MJ, Andrés Chacón-Martínez C, Latza C, Antebi A, Tessarz P, Wickström SA, Denzel MS. N1-acetylspermidine is a determinant of hair follicle stem cell fate. J Cell Sci. 2021 May 1;134(9):jcs252767. doi: 10.1242/jcs.252767. Epub 2021 May 11. PMID: 33973637.
  • Tayem R, Niemann C, Pesch M, Morgner J, Niessen CM, Wickström SA, Aumailley M (2021). LAMININ 332 IS INDISPENSABLE FOR HOMEOSTATIC EPIDERMAL DIFFERENTIATION PROGRAMS. J Invest Dermatol. 2021 May 6:S0022-202X(21)01215-X. doi: 10.1016/j.jid.2021.04.008. Epub ahead of print. PMID: 33965403.

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Rudolf J. Wiesner

  • Kimoloi S, Pla-Martín D, Oexner RR, Baris OR, Wiesner RJ (2021). Author Response: K320E-Twinkleskm Mice Are Genetically Heterogeneous for Secondary mtDNA Deletions Impairing Comparison With Controls. Invest Ophthalmol Vis Sci. 2021 Jan 4;62(1):13. doi: 10.1167/iovs.62.1.13. PMID: 33427853

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Andreas Wodarz

  • Witte L, Linnemannstöns K, Schmidt K, Honemann-Capito M, Grawe F, Wodarz A, Gross JC (2021).The kinesin motor Klp98A mediates apical to basal Wg transport.  Development. 2020 Aug 14;147(15):dev186833. doi: 10.1242/dev.186833.PMID: 32665246  
  • Linnemannstöns K, Witte L, Karuna M P, Kittel JC, Danieli A, Müller D, Nitsch L, Honemann-Capito M, Grawe F, Wodarz A, Gross JC (2021). Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium. Development. 2020 Aug 14;147(15):dev185421. doi: 10.1242/dev.185421. PMID: 32611603 

 

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Thomas Wunderlich

  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798 
  • Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC (2021). Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat Neurosci. 2021 May 17. doi: 10.1038/s41593-021-00854-0. Epub ahead of print. PMID: 34002087. 
  • Borgmann D, Ciglieri E, Biglari N, Brandt C, Cremer AL, Backes H, Tittgemeyer M, Wunderlich FT, Brüning JC, Fenselau H (2021). Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metab. 2021 May 21:S1550-4131(21)00219-9. doi: 10.1016/j.cmet.2021.05.002. Epub ahead of print. PMID: 34043943.

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Branko Zevnik

  • Tröder SE, Zevnik B (2021). History of genome editing: From meganucleases to CRISPR. Lab Anim. 2021 Feb 23;23677221994613. doi: 10.1177/0023677221994613. Online ahead of print.

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