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Leptin-sensing neurons in the lateral hypothalamus (colored green) help to overcome anxiety to enable adaptive behavioru. Input from prefrontal cortex is shown in red. White lines show the activity of individual neurons.

Eat, explore, rest: a leptin-sensing brain circuit helps overcome anxiety to meet vital needs

20.10.2025 Label 2025 Label News and Calendar Label TopNews Label Prof. Dr. Tatiana Korotkova

A research team at the University of Cologne and University Hospital Cologne identifies a circuit in the brain that counteracts…

CECAD community members gather in anticipation of the vaccination event.

CECAD Health Day: Protecting Our Community

15.10.2025 Label People Label 2025 Label TopNews

Keeping CECAD healthy against COVID-19, Flu, and RSV with a vaccination campaign

CxUb is the last unit of the polyubiquitin gene, represented here by a moving train that carries at its end a bright wagon attached to a valuable trolley, which symbolize the C-terminally extended ubiquitin, CxUb in short. The train transitions from a stormy sky, with abnormal/dark mitochondrial-shaped clouds, representing stress, to a sunny sky full of healthy/bright mitochondria, thanks to protection from CxUb. The treasure, golden clock and hourglass are metaphors for the essential functions of CxUb in stress resistance, cellular homeostasis and healthy ageing.

A quiet ally: a ubiquitin precursor promotes stress resistance and longevity

02.10.2025

In response to cellular stress, the protein CxUb is activated to identify damaged proteins, thereby maintaining cellular health.…

In mice, inflammation caused by a deficiency in DNA building blocks leads to hardening of the glomeruli in the kidneys.

Hidden cause of inflammation

25.09.2025 Label 2025 Label News and Calendar Label TopNews Label Prof. Dr. Thomas Langer

Excess RNA building blocks destabilize mitochondrial DNA

Wübben Stiftung Wissenschaft Logo

Two Master Students selected for Wübben Stiftung Wissenschaft Scholarship

18.09.2025 Label 2025 Label Award

Niklas Müller and Kyra Olechnowicz, two outstanding students of the Master’s program “Genetics and Biology of Aging and…

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