CECAD

Publications 2019

A B C D E F G H I J K L M N O P Q R S TU V W X Y Z

Adam Antebi

  • Annibal A, Tam H, Latza C, Antebi A (2019). Comparison of ESI-MS/MS and APCI-MS methods for the quantification of folic acid analogs in C. elegans. J Mass Spectrom. 2019 Apr;54(4):316-327. doi: 10.1002/jms.4337
  • Dolfi L, Ripa R, Antebi A, Valenzano DR, Cellerino A (2019). Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology. Evodevo. 2019 Nov 8;10:29. doi: 10.1186/s13227-019-0142-5. eCollection 2019  
  • Guerra BA, Brandão BB, Pinto SS, Salgueiro WG, De-Souza EA, Reis FCG, Batista TM, Cavalcante-Silva V, D'Almeida V, Castilho BA, Carneiro EM, Antebi A, Festuccia WT, Mori MA (2019). Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects. Mol Metab. 2019 Nov;29:124-135. doi:10.1016/j.molmet.2019.08.017. Epub 2019 Aug 28  
  • Calimport SRG, Bentley BL, Stewart CE, Pawelec G, Scuteri A, Vinciguerra M, Slack C, Chen D, Harries LW, Marchant G, Fleming GA, Conboy M, Antebi A, Small GW, Gil J, Lakatta EG, Richardson A, Rosen C, Nikolich K, Wyss-Coray T, Steinman L, Montine T, de Magalhães JP, Campisi J, Church G (2019). To help aging populations, classify organismal senescence. Science. 2019 Nov 1;366(6465):576-578. doi: 10.1126/science.aay7319    
  • Zhou Y, Wang X, Song M, He Z, Cui G, Peng G, Dieterich C, Antebi A, Jing N, Shen Y (2019). A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing. Nat Commun. 2019 Oct 23;10(1):4827. doi: 10.1038/s41467-019-12821-2     
  • Lesanpezeshki L, Hewitt JE, Laranjeiro R, Antebi A, Driscoll M, Szewczyk NJ, Blawzdziewicz J, Lacerda CMR, Vanapalli SA (2019). Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans. Sci Rep. 2019 Oct 23;9(1):15246. doi: 10.1038/s41598-019-51608-9    
  • Fischer J, Gutièrrez S, Ganesan R, Calabrese C, Ranjan R, Cildir G, Hos NJ, Rybniker J, Wolke M, Fries JWU, Tergaonkar V, Plum G, Antebi A, Robinson N (2019). Leptin signaling impairs macrophage defenses against Salmonella Typhimurium. Proc Natl Acad Sci USA. 2019 Aug 13;116(33):16551-16560. doi: 10.1073/pnas.1904885116. Epub 2019 Jul 26     
  • Antebi A (2019).Developmental Timing: Honey, I Reprogrammed the Kids. Curr Biol. 2019 Jun 3;29(11):R420-R422. doi: 10.1016/j.cub.2019.04.054 
  • De-Souza EA, Camara H, Salgueiro WG, Moro RP, Knittel TL, Tonon G, Pinto S, Pinca APF, Antebi A, Pasquinelli AE, Massirer KB, Mori MA (2019). RNA interference may result in unexpected phenotypes in Caenorhabditis elegans. Nucleic Acids Res. 2019 May 7;47(8):3957-3969. doi: 10.1093/nar/gkz154      
  • Nakamura S, Oba M, Suzuki M, Takahashi A, Yamamuro T, Fujiwara M, Ikenaka K, Minami S, Tabata N, Yamamoto K, Kubo S, Tokumura A, Akamatsu K, Miyazaki Y, Kawabata T, Hamasaki M, Fukui K, Sango K, Watanabe Y, Takabatake Y, Kitajima TS, Okada Y, Mochizuki H, Isaka Y, Antebi A, Yoshimori T (2019). Suppression of autophagic activity by Rubicon is a signature of aging. Nat Commun. 2019 Feb 19;10(1):847. doi: 10.1038/s41467-019-08729-6

Thomas Benzing

  • Braun F, Blomberg L, Brodesser S, Liebau MC, Schermer B, Benzing T, Kurschat CE (2019). Enzyme Replacement Therapy Clears Gb3 Deposits from a Podocyte Cell Culture Model of Fabry Disease but Fails to Restore Altered Cellular Signaling. Cell Physiol Biochem. 2019;52(5):1139-1150. doi: 10.33594/000000077  
  • Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM (2019). The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2019 Feb;95(2):333-349. doi: 10.1016/j.kint.2018.08.037. Epub 2018 Dec 3    
  • Ignarski M, Rill C, Kaiser RWJ, Kaldirim M, Neuhaus R, Esmaillie R, Li X, Klein C, Bohl K, Petersen M, Frese CK, Höhne M, Atanassov I, Rinschen MM, Höpker K, Schermer B, Benzing T, Dietrich C, Fabretti F, Müller RU (2019). The RNA-protein interactome of differentiated kidney tubular epithelial cells. J Am Soc Nephrol. 2019 Apr;30(4):564-576. doi: 10.1681/ASN.2018090914. Epub 2019 Mar 13
  • Jain M, Kaiser RWJ, Bohl K, Hoehne M, Göbel H, Bartram MP, Habbig S, Müller RU, Fogo AB, Benzing T, Schermer B, Höpker K, Slaats GG (2019). Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis. Kidney Int. 2019 Apr;95(4):846-858. doi: 10.1016/j.kint.2018.10.034. Epub 2019 Feb 13  
  • Braun F, Suarez V, Dinter J, Haneder S, Quaas A, Benzing T, Nierhoff D, Müller RU (2019). Successful use of TNFα blockade in a severe case of idiopathic non-granulomatous ulcerative jejunoileitis associated with thrombotic thrombocytopenic purpura. BMJ Open Gastroenterol. 2019 Feb 8;6(1):e000252. doi: 10.1136/bmjgast-2018-000252. eCollection 2019

to top

Matteo Bergami

  • Sprenger HS, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2019). Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 2019 Jan;11(1). pii: e9288. doi: 10.15252/emmm.201809288  

to top

Andreas Beyer

  • Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM (2019). The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2019 Feb;95(2):333-349. doi: 10.1016/j.kint.2018.08.037. Epub 2018 Dec 3

to top

Susanne Brodesser

  • Yu H, Dilbaz S, Coßmann J, Hoang AC, Diedrich V, Herwig A, Harauma A, Hoshi Y, Moriguchi T, Landgraf K, Körner A, Lucas C, Brodesser S, Balogh L, Thuróczy J, Karemore G, Kuefner MS, Park EA, Rapp C, Travers JB, Röszer T (2019). Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages. J Clin Invest. 2019 May 13;130:2485-2499. doi: 10.1172/JCI125646. eCollection 2019 May 13
  • Braun F, Blomberg L, Brodesser S, Liebau MC, Schermer B, Benzing T, Kurschat CE (2019). Enzyme Replacement Therapy Clears Gb3 Deposits from a Podocyte Cell Culture Model of Fabry Disease but Fails to Restore Altered Cellular Signaling. Cell Physiol Biochem. 2019;52(5):1139-1150. doi: 10.33594/000000077
  • Murru S, Hess S, Barth E, Almajan ER, Schatton D, Hermans S, Brodesser S, Langer T, Kloppenburg P, Rugarli EI (2019). Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019 Aug;67(8):1526-1541. doi: 10.1002/glia.23626. Epub 2019 Apr 16
  • Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling JE, Dodzian J, Lagerborg KA, Vargas NE, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano DR, Kurian L (2019). Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep. 2019 Apr;20(4). pii: e47407. doi: 10.15252/embr.201847407. Epub 2019 Mar 18
  • Farowski F, Solbach P, Tsakmaklis A, Brodesser S, Cruz Aguilar MR, Cornely OA, Dettmer K, Higgins PG, Suerbaum S, Jazmati N, Oefner PJ, Vehreschild MJGT (2019). Potential biomarkers to predict outcome of faecal microbiota transfer for recurrent Clostridioides difficile infection. Dig Liver Dis. 2019 Jul;51(7):944-951. doi: 10.1016/j.dld.2019.01.012. Epub 2019 Jan 26
  • Turpin-Nolan SM, Hammerschmidt P, Chen W, Jais A, Timper K, Awazawa M, Brodesser S, Brüning JC (2019). CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Rep. 2019 Jan 2;26(1):1-10.e7. doi: 10.1016/j.celrep.2018.12.031
  • Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM (2019). The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2019 Feb;95(2):333-349. doi: 10.1016/j.kint.2018.08.037. Epub 2018 Dec 3
  • Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin P, Baraibar MA, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M (2019). Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy. EMBO J. 2019 Jan 3;38(1). pii: e99576. doi: 10.15252/embj.201899576. Epub 2018 Nov 12

to top

Jens Brüning  

  • Turpin-Nolan SM, Hammerschmidt P, Chen W, Jais A, Timper K, Awazawa M, Brodesser S, Brüning JC (2019). CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Rep. 2019 Jan 2;26(1):1-10.e7. doi: 10.1016/j.celrep.2018.12.031 
  • Thanarajah SE, Backes H, DiFeliceantonio AG, Albus K, Cremer AL, Hanssen R, Lippert RN, Cornely OA, Small DM, Bruning JC, Tittgemeyer M (2019). Food Intake Recruits Orosensory and Post-ingestive Dopaminergic Circuits to Affect Eating Desire in Humans. Cell Metab. 2019 Mar 5;29(3):695-706.e4. doi: 10.1016/j.cmet.2018.12.006. Epub 2018 Dec 27

to top

Oliver Cornely

  • Seidel D, Meissner A, Lackner M, Piepenbrock E, Salmanton-Garcia J, Stecher M, Mellinghoff S, Hamprecht A, Duran Graeff L, Kohler P, Cheng MP, Denis J, Chedotal I, Chander J, Pakstis DL, Los-Arcos I, Slavin M, Montagna MT, Caggiano G, Mares M, Trauth J, Aurbach U, Vehreschild M, Vehreschild JJ, Duarte RF, Herbrecht R, Wisplinghoff H, Cornely OA (2019). Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope((R)). Crit Rev Microbiol. 2019 Feb;45(1):1-21. doi: 10.1080/1040841X.2018.1514366. Epub 2019 Jan 10
  • Mellinghoff SC, Vehreschild JJ, Liss BJ, Cornely OA (2019). Metadata Correction: Epidemiology of Surgical Site Infections With Staphylococcus aureus in Europe: Protocol for a Retrospective, Multicenter Study. JMIR Res Protoc. 2019 Jan 7;8(1):e10712. doi: 10.2196/10712
  • Koehler P, Mellinghoff SC, Lagrou K, Alanio A, Arenz D, Hoenigl M, Koehler FC, Lass-Florl C, Meis JF, Richardson M, Cornely OA (2019). Development and validation of the European QUALity (EQUAL) score for mucormycosis management in haematology. J Antimicrob Chemother. 2019 Jun 1;74(6):1704-1712. doi: 10.1093/jac/dkz051
  • Koehler P, Jung N, Cornely OA, Rybniker J, Fatkenheuer G (2019). Combination Antimicrobial Therapy for Enterococcus faecalis Infective Endocarditis. Clin Infect Dis. 2019 Feb 1. doi: 10.1093/cid/ciz054. [Epub ahead of print
  • Gerding DN, Cornely OA, Grill S, Kracker H, Marrast AC, Nord CE, Talbot GH, Buitrago M, Gheorghe Diaconescu I, Murta de Oliveira C, Preotescu L, Pullman J, Louie TJ, Wilcox MH (2019). Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trials. Lancet Infect Dis. 2019 Mar;19(3):265-274. doi: 10.1016/S1473-3099(18)30614-5. Epub 2019 Jan 29
  • Farowski F, Solbach P, Tsakmaklis A, Brodesser S, Cruz Aguilar MR, Cornely OA, Dettmer K, Higgins PG, Suerbaum S, Jazmati N, Oefner PJ, Vehreschild MJGT (2019). Potential biomarkers to predict outcome of faecal microbiota transfer for recurrent Clostridioides difficile infection. Dig Liver Dis. 2019 Jul;51(7):944-951. doi: 10.1016/j.dld.2019.01.012. Epub 2019 Jan 26
  • Oladele RO, Osaigbovo, II, Ayanlowo OO, Otu AA, Hoenigl M, Cornely OA, Chakrabarti A, Denning DW (2019). The role of medical mycology societies in combating invasive fungal infections in low- and middle-income countries: A Nigerian model. Mycoses 2019 Jan;62(1):16-21. doi: 10.1111/myc.12845. Epub 2018 Oct 8       
  • Mellinghoff SC, von Bergwelt-Baildon M, Schosser HA, Cornely OA (2019). A novel approach to candidemia? The potential role of checkpoint inhibition. Med Mycol. 2019 Feb 1;57(2):151-154. doi: 10.1093/mmy/myy089  
  • Thanarajah SE, Backes H, DiFeliceantonio AG, Albus K, Cremer AL, Hanssen R, Lippert RN, Cornely OA, Small DM, Bruning JC, Tittgemeyer M (2019). Food Intake Recruits Orosensory and Post-ingestive Dopaminergic Circuits to Affect Eating Desire in Humans. Cell Metab. 2019 Mar 5;29(3):695-706.e4. doi: 10.1016/j.cmet.2018.12.006. Epub 2018 Dec 27  

Martin Denzel

  • Sawarkar R, Scherz-Shouval R, Denzel MS, Saarikangas J (2019). Chaperoning junior faculty: Institutional support and guidance can relieve challenges for early-career group leaders and improve academic performance. EMBO Rep. 2019 Jan;20(1). pii: e47163. doi: 10.15252/embr.201847163. Epub 2018 Nov 23    

Sabine Eming

  • Kiesewetter A, Cursiefen C, Eming SA, Hos D (2019). Phase-specific functions of macropahges determine injury-medoated coneal hem- and lymphangiogenesis. Sci Rep 9:308

Mafalda Escobar-Henriques

  • Escobar-Henriques M, Joaquim M (2019). Mitofusins: Disease Gatekeepers and Hubs in Mitochondrial Quality Control by E3 Ligases. Front Physiol. 2019 May 9;10:517. doi: 10.3389/fphys.2019.00517. eCollection 2019
  • Escobar-Henriques M, Altin S, Brave FD (2019). Interplay between the Ubiquitin Proteasome System and Mitochondria for Protein Homeostasis. Curr Issues Mol Biol. 2019 Aug 18;35:35-58. doi: 10.21775/cimb.035.035. [Epub ahead of print]

Martin Graef

  • Medeiros TC, Graef M (2019). Autophagy determines mtDNA copy number dynamics during starvation. Autophagy. 2019 Jan;15(1):178-179. doi: 10.1080/15548627.2018.1532263. Epub 2018 Oct 13

Matthias Hammerschmidt

  • Turpin-Nolan SM, Hammerschmidt P, Chen W, Jais A, Timper K, Awazawa M, Brodesser S, Brüning JC (2019). CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Rep. 2019 Jan 2;26(1):1-10.e7. doi: 10.1016/j.celrep.2018.12.031

to top

Thorsten Hoppe       

  • Finger F, Ottens F, Springhorn A, Drexel T, Proksch L, Metz S, Cochella L, Hoppe T (2019). Olfaction regulates organismal proteostasis and longevity via miRNA-dependent signaling. Nat. Metab. (in press)          
  • Springhorn A, Hoppe T (2019). Western blot analysis of the autophagosomal membrane protein LGG-1/LC3 in Caenorhabditis elegans. Method Enzymol. 2019;619:319-336. doi: 10.1016/bs.mie.2018.12.034. Epub 2019 Feb 4     
  • Herzog LK, Kevei É, Marchante R, Böttcher C, Bindesbøll C, Lystad AH, Pfeiffer A, Gierisch ME, Salomons FA, Simonsen A, Hoppe T, Dantuma NP (2019). The Machado–Joseph disease deubiquitylase ataxin‐3 interacts with LC3C/GABARAP and promotes autophagy. Aging Cell. 2019 Oct 17:e13051. doi: 10.1111/acel.13051. [Epub ahead of print]    
  • Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB. Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, Hoppe T, Kaeberlein M, Katajisto P, Kennedy BK, Lal U, Martin-Villalba A, Moskalev AA, Ozerov I, Petr MA, Reason, Rubinsztein DC, Tyshkovskiy A, Vanhaelen Q, Zhavoronkov A, Scheibye-Knudsen M (2019). Latest advances in aging research and drug discovery. Aging-US. 2019 Nov 21;11. doi: 10.18632/aging.102487. [Epub ahead of print]     
  • Ottens F, Finger F, Hoppe T (2019). Wie der Geruch von Nahrung Stoffwechsel und Altern beeinflusst. Nutrition News 3, 3-5.

Tamas Horvath      

  • Stutz B, Nasrallah C, Nigro M, Curry D, Liu ZW, Gao XB, Elsworth JD, Mintz L, Horvath TL (2019). Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activity. Mol Metab. 2019 Jun;24:120-138. doi: 10.1016/j.molmet.2019.02.005. Epub 2019 Feb 21
  • Seli E, Wang T, Horvath TL (2019). Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging. Fertil Steril. 2019 Feb;111(2):197-204. doi: 10.1016/j.fertnstert.2018.11.048

Sandra Iden 

  • Dias Gomes M*, Letzian S*, Saynisch M, and Iden S (2019). Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity. Nature Communications 10, 3362 (*equal contribution)  https://rdcu.be/bMftV

to top

Frank Jessen

  • Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roschupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L,  Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall  DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG,  Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y; Alzheimer Disease Genetics Consortium (ADGC),; European Alzheimer’s Disease Initiative (EADI),; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE),; Genetic and Environmental Risk inAD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES),, Pilotto A, Bullido MJ, Peters O, Crane PK, BennettD, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL,Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM,Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, C O'Donovan M, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA (2019). Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 Mar;51(3):414-430. doi:10.1038/s41588-019-0358-2. Epub 2019 Feb 28. PubMed PMID: 30820047
  • Escher CM, Sannemann L, Jessen F (2019). Stress and Alzheimer's disease. J Neural Transm (Vienna). 2019 Feb 20. doi: 10.1007/s00702-019-01988-z. [Epub ahead of print]
  • Dalmasso MC, Brusco LI, Olivar N, Muchnik C, Hanses C, Milz E, Becker J, Heilmann-Heimbach S, Hoffmann P, Prestia FA, Galeano P, Avalos MSS, Martinez LE, Carulla ME, Azurmendi PJ, Liberczuk C, Fezza C, Sampaño M, Fierens M, Jemar G, Solis P, Medel N, Lisso J, Sevillano Z, Bosco P, Bossù P, Spalletta G, Galimberti D, Mancuso M, Nacmias B, Sorbi S, Mecocci P, Pilotto A, Caffarra P, Panza F, Bullido M, Clarimon J, Sánchez-Juan P, Coto E, Sanchez-Garcia F, Graff C, Ingelsson M, Bellenguez C, Castaño EM, Kairiyama C, Politis DG, Kochen S, Scaro H, Maier W, Jessen F, Mangone CA, Lambert JC, Morelli L, Ramirez A (2019). Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer's disease. Transl Psychiatry. 2019 Jan 31;9(1):55. doi: 10.1038/s41398-019-0394-9. PubMed PMID: 30705288; PubMed Central PMCID: PMC6355764
  • Haidl TK, Seves M, Eggers S, Rostamzadeh A, Genske A, Jünger S, Woopen C, Jessen F, Ruhrmann S, Vogeley K (2019). Health literacy in clinical-high-risk individuals for psychosis: A systematic mixed-methods review. Early Interv Psychiatry. 2019 Jan 27. doi: 10.1111/eip.12776. [Epub ahead of print] Review. PubMed PMID: 30688012
  • Jessen F (2019). Early detection of Alzheimer's disease and approaches for prevention. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Jan 24. doi: 10.1007/s00103-019-02877-2. [Epub ahead of print] Review. German. PubMed PMID: 30680409
  • Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padrós N, Bouwman FH, Slot RER, Wesselman LMP, Peters O, Luther K, Buerger K, Priller J, Laske C, Teipel S, Spottke A, Heneka MT, Düzel E, Drzezga A, Wiltfang J, Sikkes SAM, van der Flier WM, Jessen F, Euro-SCD working group (2019). Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimers Res Ther. 2019 Jan 17;11(1):8. doi: 10.1186/s13195-018-0463-y. PubMed PMID: 30654834; PubMed Central PMCID: PMC6337830
  • Jagust W, Jack CR Jr, Bennett DA, Blennow K, Haeberlein SB, Holtzman DM, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Sperling R (2019). "Alzheimer's disease" is neither "Alzheimer's clinical syndrome" nor "dementia". Alzheimers Dement. 2019 Jan;15(1):153-157. doi: 10.1016/j.jalz.2018.11.002. PubMed PMID: 30642435
  • Meiberth D, Rapp MA, Jessen F (2019). Memory Clinics in Germany - Results of a Hospital Survey. Psychiatr Prax. 2019 Jan 14. doi: 10.1055/a-0825-9049. [Epub ahead of print] German. PubMed PMID: 30641612
  • Schüller CB, Kuhn J, Jessen F, Hu X (2019). Neuronal correlates of delay discounting in healthy subjects and its implication for addiction: an ALE meta-analysis study. Am J Drug Alcohol Abuse. 2019;45(1):51-66. doi:10.1080/00952990.2018.1557675. Epub 2019 Jan 11. PubMed PMID: 30632802

Hamid Kashkar

  • Habich M, Salscheider S, Murschall L, Hoehne M, Fischer M, Schorn F, Petrungaro C, Ali M, Erdogan A, Abou-Eid S, Kashkar H, Dengjel J, Riemer J (2019). Vectorial import via a metastable disulphide-linked complex allows for a quality control step and efficient import by the mitochondrial disulphide relay Cell Rep. 2019 Jan 15;26(3):759-774.e5. doi: 10.1016/j.celrep.2018.12.092

to top

Peter Kloppenburg

  • Murru S, Hess S, Barth E, Almajan ER, Schatton D, Hermans S, Brodesser S, Langer T, Kloppenburg P, Rugarli EI (2019). Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019 Aug;67(8):1526-1541. doi: 10.1002/glia.23626. Epub 2019 Apr 16

 

to top

Natalia Kononenko

  • Upadhyay A, Hosseinibarkooie M, Schneider S, Kaczmarek A, Torres-Benito L, Natalia Mendoza-Ferreira N, Overhoff M, Rombo R, Grysko V, Kye MJ, Kononenko NL, Wirth B (2019). Neurocalcin delta knockout impairs adult neurogenesis whereas half reduction is a safe therapeutic option for spinal muscular atrophy. Front Mol Neurosci. 2019 Feb 12. doi: 10.3389/fnmol.2019.00019
  • Kononenko NL, Hartfil S, Willer J, Ferch J, Wolfenberg H, Pflueger HJ (2019). A population of descending tyraminergic/octopaminergic projection neurons of the insect. J Comp Neurol. Apr 15;527:1027-1038 (2019)

Marcus Krüger

  • Jachimowicz RD, Bhavana VB, Beleggia F, Isensee J, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y(2019). UBQLN4 regulates double-strand break repair by repressing homologous recombination and is overexpressed in aggressive tumors, Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3

Leo Kurian

  • Frank S, Ahuja G, Bartsch D, Russ N, Yao W,  Kuo JC, Derks JP,  Akhade VS, Kargapolova Y, Georgomanolis T, Messling J, Gramm M, Brant L, Rehimi R, Vargas NE, Kuroczik, Yang TP, Sahito RGA, Franzen J, Hescheler J, Sachinidis A, Peifer M, Rada-Iglesias A, Kanduri M, Costa IG, Kanduri C, Papantonis A, Kurian L (2019). yylncT defines a class of divergently-transcribed lncRNAs and safeguards the T-mediated mesodermal commitment of human PSCs. Cell Stem Cell. 2019 Feb 7;24(2):318-327.e8. doi: 10.1016/j.stem.2018.11.005. Epub 2018 Dec 13      
  • Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling J,Dodzian J, Lehmann K, Vargas N, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano D, Kurian L (2019). Loss of genomic integrity by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep. 2019 Apr;20(4). pii: e47407. doi: 10.15252/embr.201847407. Epub 2019 Mar 18            
  • Kuo CC, Hanzelmann S, Sentürk N, Frank S, Zajzon B, Derks JP, Akhade VS, Ahuja G, Kanduri C, Grummt I, Kurian L, Costa IG (2019).  Detection of RNA–DNA binding sites in long noncoding RNAs. Nucleic Acids Res. 2019 Apr 8;47(6):e32. doi: 10.1093/nar/gkz037         
  • Bender D, Kaczmarek AT, Santamaria-Araujo JA, Stueve B, Waltz S, Bartsch D, Kurian L, Cirak S, Schwarz G (2019). Impaired mitochondrial maturation of sulfite oxidase in a patient with severe sulfite oxidase deficiency. Hum Mol Genet. 2019 Sep 1;28(17):2885-2899. doi: 10.1093/hmg/ddz109

Thomas Langer

  • Murru S, Hess S, Barth E, Almajan ER, Schatton D, Hermans S, Brodesser S, Langer T, Kloppenburg P, Rugarli EI (2019). Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019 Aug;67(8):1526-1541. doi: 10.1002/glia.23626. Epub 2019 Apr 16
  • Miliara X, Tatsuta T, Berry JL, Rouse SL, Solak K, Chorev DS, Wu D, Robinson CV, Matthews S, Langer T (2019). Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins. Nat Commun. 2019 Mar 8;10(1):1130. doi: 10.1038/s41467-019-09089-x
  • Sprenger HS, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2019). Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 2019 Jan;11(1). pii: e9288. doi: 10.15252/emmm.201809288                  
  • Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin PA, Baraibar M, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M (2019). Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy. Embo J. 2019 Jan 3;38(1). pii: e99576. doi: 10.15252/embj.201899576. Epub 2018 Nov12               
  • Richter F, Dennerlein S, Nikolov M, Jans D, Naumenko N, Aich A, MacVicar T, Linden A, Jakobs S, Urlaub H, Langer T, Rehling P (2019). ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. J Cell Biol. 4;218(2):598-614. doi: 10.1083/jcb.201806093-

Roman-Ulrich Müller

  • Ignarski M, Rill C, Kaiser RWJ, Kaldirim M, Neuhaus R, Esmaillie R, Li X, Klein C, Bohl K, Petersen M, Frese CK, Hoehne M, Atanassov I, Rinschen MM, Höpker K, Schermer B, Benzing T, Dietrich C, Fabretti F, Müller RU (2019). The RNA-protein interactome of differentiated kidney tubular epithelial cells. J Am Soc Nephrol. 2019 Apr;30(4):564-576. doi: 10.1681/ASN.2018090914. Epub 2019 Mar 13
  • Jain M, Kaiser RWJ, Bohl K, Hoehne M, Göbel H, Bartram MP, Habbig S, Müller RU, Fogo AB, Benzing T, Schermer B, Höpker K, Slaats GG (2019). Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis. Kidney Int. 2019 Apr;95(4):846-858. doi: 10.1016/j.kint.2018.10.034. Epub 2019 Feb 13
  • Rinschen MM, Müller RU (2019). A knowledge-guided kidney cell census-reconciling bulk omics with cellular heterogeneity? Kidney Int. 2019 Apr;95(4):733-735. doi: 10.1016/j.kint.2018.12.016
  • Braun F, Suarez V, Dinter J, Haneder S, Quaas A, Benzing T, Nierhoff D, Müller RU (2019). Successful use of TNFα blockade in a severe case of idiopathic non-granulomatous ulcerative jejunoileitis associated with thrombotic thrombocytopenic purpura. BMJ Open Gastroenterol. 2019 Feb 8;6(1):e000252. doi: 10.1136/bmjgast-2018-000252. eCollection 2019     
  • Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM (2019). The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2019 Feb;95(2):333-349. doi: 10.1016/j.kint.2018.08.037. Epub 2018 Dec 3

Carien Niessen

  • Persa OD, Niessen CM (2019). Epithelial polarity limits EMT. Nat Cell Biol. 2019 Mar;21(3):299-300. doi: 10.1038/s41556-019-0284-7

Peter Nürnberg

  • Prasetyanti PR, Hooff SR van, van Herwaarden T, de Vries N, Kalloe K, Rodermond H, van Leersum R, de Jong JH, Franitza M, Nurnberg P, Todaro M, Stassi G, Medema JP (2019). Capturing colorectal cancer inter-tumor heterogeneity in patient-derived xenograft (PDX) models. Int J Cancer. 2019 Jan 15;144(2):366-371. doi: 10.1002/ijc.31767. Epub 2018 Oct 22

Linda Partridge

  • Weigelt CM, Hahn O, Arlt K, Gruhn M, Jahn AJ, Esser J, Werner JA, Klein C, Buschges A, Gronke S, Partridge L (2019). Loss of miR-210 leads to progressive retinal degeneration in Drosophila melanogaster. Life Sci Alliance. 2019 Jan 22;2(1). pii: e201800149. doi: 10.26508/lsa.201800149. Print 2019 Feb
  • Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019). Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol. 2019 Jan 9;15(1):e1006639. doi: 10.1371/journal.pcbi.1006639. eCollection 2019 Jan
  • Moens TG, Niccoli T, Wilson KM, Atilano ML, Birsa N, Gittings LM, Holbling BV, Dyson MC, Thoeng A, Neeves J, Glaria I, Yu L, Bussmann J, Storkebaum E, Pardo M, Choudhary JS, Fratt, P, Partridge L, Isaacs AM (2019). C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A. Acta Neuropathol. 2019 Mar;137(3):487-500. doi: 10.1007/s00401-018-1946-4. Epub 2019 Jan 2

Manolis Pasparakis  

  • Krishna-Subramanian S, Singer S, Armaka M, Banales JM, Holzer K, Schirmacher P, Walczak H, Kollias G, Pasparakis M, Kondylis V (2019). RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ. 2019 Apr 15. doi: 10.1038/s41418-019-0330-9. [Epub ahead of print]
  • Kondylis V, Pasparakis M (2019). RIP Kinases in Liver Cell Death, Inflammation and Cancer. Trends Mol Med. 2019 Jan;25(1):47-63. doi: 10.1016/j.molmed.2018.10.007. Epub 2018 Nov 16      
  • Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand AJ, Robertson D, Feltham R, Anderton H, Darding M, Peltzer N, Dannappel M, Schünke H, Fava LL, Haschka MD, Glatter T, Nesvizhskii A, Schmidt A, Harris PA, Bertin J, Gough PJ, Villunger A, Silke J, Pasparakis M, Bianchi K, Meier P (2019). RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol Cell. 2019 Feb 7;73(3):413-428.e7. doi: 10.1016/j.molcel.2018.11.010. Epub 2018 Dec 28               
  • Koliaraki V, Chalkidi N, Henriques A, Tzaferis C, Polykratis A, Waisman A, Muller W, Hackam DJ, Pasparakis M, Kollias G (2019). Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis. Cell Rep. 2019 Jan 15;26(3):536-545.e4. doi: 10.1016/j.celrep.2018.12.072              
  • Gräb J, Suárez I, van Gumpel E, Winter S, Schreiber F, Esser A, Hölscher C, Fritsch M, Herb M, Schramm M, Wachsmuth L, Pallasch C, Pasparakis M, Kashkar H, Rybniker J (2019). Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition. Nat Commun. 2019 Feb 8;10(1):688. doi: 10.1038/s41467-019-08405-9
  • Eftychi C, Schwarzer R, Vlantis K, Wachsmuth L, Basic M, Wagle P, Neurath MF, Becker C, Bleich A, Pasparakis M. (2019)Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment. Immunity (2019) Jul 16. pii: S1074-7613(19)30278-X.  doi: 10.1016/j.immuni.2019.06.008
  • Polykratis A, Martens A, Eren RO, Shirasaki Y, Yamagishi M, Yamaguchi Y, Uemura S, Miura M, Holzmann B, Kollias G, Armaka M, van Loo G, Pasparakis M. (2019). A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain. Nature Cell Biology 2019 Jun;21(6):731-742. doi: 10.1038/s41556-019-0324-3.
  • Wong J, Garcia-Carbonell R, Zelic M, Ho SB, Boland BS, Yao SJ, Desai SA, Das S, Planell N, Harris PA, Font-Burgada J, Taniguchi K, Bertin J, Salas A, Pasparakis M, Gough PJ, Kelliher M, Karin M, Guma M. RIPK1 mediates TNF-induced intestinal crypt apoptosis during chronic NF-κB activation. Cell Mol Gastroenterol Hepatol. 2019 Oct 10. pii: S2352-345X(19)30138-9. doi: 10.1016/j.jcmgh.2019.10.002. [Epub ahead of print]
  • D'Cruz AA, Speir M, Bliss-Moreau M, Dietrich S, Wang S, Chen AA, Gavillet M, Al-Obeidi A, Lawlor KE, Vince JE, Kelliher MA, Hakem R, Pasparakis M, Williams DA, Ericsson M, Croker BA. The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils. Sci Signal. 2018 Sep 4;11(546). pii: eaao1716. doi: 10.1126/scisignal.aao1716.
  • Priem D, Devos M, Druwé S, Martens A, Slowicka K, Ting AT, Pasparakis M, Declerq W, Vandenabeele P, van Loo G, Bertrand MJM. A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms. Cell Death Dis. 2019 Sep 18;10(10):692. doi: 10.1038/s41419-019-1937-y.

Hans Christian Reinhardt

  • Jachimowicz RD, Bhavana VB, Beleggia F, Isensee J, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y(2019). UBQLN4 regulates double-strand break repair by repressing homologous recombination and is overexpressed in aggressive tumors, Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3     
  • Castiglione R, Alidousty C, Holz B, Wagener S, Baar T, Heydt C, Binot E, Zupp S, Kron A, Wolf J, Merkelbach-Bruse S, Reinhardt HC, Büttner R, Schultheis AM (2019). Comparison of the genomic background of MET-altered carcinomas of the lung: biological differences and analogies. Mod Pathol. 2019 May;32(5):627-638. doi: 10.1038/s41379-018-0182-8. Epub 2018 Nov 20
  • Grimm C, Fischer A, Farrelly AM, Kalachand R, Castiglione R, Wasserburger E, Hussong M, Schultheis A, Altmüller J, Thiele H, Reinhardt HC, Hauschulz K, Hennessy BT, Herwig R, Lienhard M, Büttner R, Schweiger MR (2019). Combined targeted re-sequencing of cytosine DNA methylations and mutations for the determination of PARP1 inhibitor sensitivity. J Mol Diagn. 2019 Mar;21(2):198-213. doi: 10.1016/j.jmoldx.2018.10.007. Epub 2018 Dec 19

to top

Elena Rugarli

  • Iershov A, Nemazanyy I, Alkhoury C, Girard M, Barth E, Cagnard N, Montagner A, Chretien D, Rugarli EI, Guillou H, Pende M, Panasyuk G. The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα. Nat Commun. 2019 Apr 5;10(1):1566. doi: 10.1038/s41467-019-09598-9. PMID: 30952952
  • Murru S, Hess S, Barth E, Almajan ER, Schatton D, Hermans S, Brodesser S, Langer T, Kloppenburg P, Rugarli EI (2019). Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019 Aug;67(8):1526-1541. doi: 10.1002/glia.23626. Epub 2019 Apr 16
  • Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola A, Wai T, Barth E, Rugarli EI, Bergami M, and Langer T. (2019) Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 11, pii: e9288. doi 10.15252/emmm. 201809288

Björn Schumacher

  • Jachimowicz RD, Bhavana VB, Beleggia F, Isensee J, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y(2019). UBQLN4 regulates double-strand break repair by repressing homologous recombination and is overexpressed in aggressive tumors, Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3  
  • Doll MA, Soltanmohammadi N, Schumacher B (2019). ALG-2/AGO-Dependent mir-35 Family Regulates DNA Damage-Induced Apoptosis Through MPK-1/ERK MAPK Signaling Downstreamof the Core Apoptotic Machinery in Caenorhabditis elegans. Genetics. 2019 Jul 11. pii: genetics.302458.2019. doi: 10.1534/genetics.119.302458.
  • Ou HL, Kim CS, Uszkoreit S, Wickström SA, Schumacher B (2019). Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells. Dev Cell. 2019 Jul 22;50(2):167-183.e8. doi: 10.1016/j.devcel.2019.06.012.

Eline Slagboom

  • Berg N van den, Rodríguez-Girondo M, van Dijk IK, Mourits RJ, Mandemakers K, Janssens AAPO, Beekman M, Smith KR, Slagboom PE (2019). Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait. Nat Commun. 2019 Jan 7;10(1):35. doi: 10.1038/s41467-018-07925-0
  • De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM (2019). L1 drives IFN in senescent cells and promotes age-associated inflammation. Nature. 2019 Feb;566(7742):73-78. doi: 10.1038/s41586-018-0784-9
  • Meessen JMTA, Fiocco M, Leichtenberg CS, Vliet Vlieland TPM, Slagboom PE, Nelissen RGHH (2019). Frailty Questionnaire Is Not a Strong Prognostic Factor for Functional Outcomes in Hip or Knee Arthroplasty Patients. Geriatr Orthop Surg Rehabil. 2019 Feb 4;10:2151459318808164. doi: 10.1177/2151459318808164 
  • Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, SlagboomPE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium (2018). Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology. 2019 Jan 16. pii: 10.1212/WNL.0000000000006851. doi: 10.1212/WNL.0000000000006851. [Epub ahead of print]

Marc Tittgemeyer

  • Baldermann JC, Melzer C, Zapf A, Kohl S, Timmermann L, Tittgemeyer M, Huys D, Visser-Vandewalle V, Kühn AA, Horn A and Kuhn J (2019). Connectivity profile predictive of effective deep brain stimulation in obsessive compulsive disorder. Biol Psychiatry. 2019 May 1;85(9):735-743. doi: 10.1016/j.biopsych.2018.12.019. Epub 2019 Jan 9
  • Glaab E, Trezzi JP, Greuel A, Jaeger C, Hodak Z, Drzezga A, Timmermann L, Tittgemeyer M, Diederich NJ, Eggers C (2019). Integrative analysis of blood metabolomics and PET brain neuroimaging data for Parkinson’s disease. Neurobiol Dis. 2019 Apr;124:555-562. doi: 10.1016/j.nbd.2019.01.003. Epub 2019 Jan 
  • Hammes J, Theis H, Giehl K, Hoenig MC, Greuel A, Tittgemeyer M, Timmermann L, Fink GR, Drzezga A, Eggers C, van Eimeren T (2019). Dopamine metabolism of the nucleus accumbens and fronto-striatal connectivity modulate impulse control. Brain. 2019 Mar 1;142(3):733-743. doi: 10.1093/brain/awz007
  • Lippert RN, Cremer AL, Edwin Thanarajah S, Korn C, Jajans-Price T, Burgeno LM, Tittgemeyer M, Bruening JC, Walton ME, Backes H (2019). Time-dependent assessment of stimulus-evoked regional dopamine release. Nat Commun. 2019 Jan 18;10(1):336. doi: 10.1038/s41467-018-08143-4     
  • Edwin Thanarajah S, Backes H, DiFeliceantonio A, Albus K, Cremer AL, Hanssen R, Lippert RN, Cornely OA, Small DM, Bruening JC, Tittgemeyer M (2019) Food intake recruits orosensory and post-ingestive dopaminergic circuits to affect eating desire in humans. Cell Metabolism 2019 Mar 5;29(3):695-706.e4. doi: 10.1016/j.cmet.2018.12.006. Epub 2018 Dec 27

Alexandra Trifunovic

  • Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling JE, Dodzian J, Lagerborg KA, Vargas NE, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano DR, Kurian L (2019). Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep. 2019 Apr;20(4). pii: e47407. doi: 10.15252/embr.201847407. Epub 2019 Mar 18

to top

Mirka Uhlirova

  • Mundorf J, Donohoe CD, McClure CD, Southall TD, Uhlirova M (2019). Ets21c governs tissue renewal, stress tolerance, and aging in the Drosophila intestine. Cell Rep. 27, 3019-3033.e5
  • Cosolo A, Jaiswal J, Csordás G, Grass I, Uhlirova M, Classen A (2019). JNK-dependent cell 1 cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress. ELife. 8:e41036. DOI: 10.7554/eLife.41036

Dario Valenzano

  • Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling JE, Dodzian J, Lagerborg KA, Vargas NE, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano DR, Kurian L (2019). Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep. 2019 Apr;20(4). pii: e47407. doi: 10.15252/embr.201847407. Epub 2019 Mar 18
  • Keesey I, Grabe V, Gruber L, Koerte S, Obiero G, Bolton G, Khallaf M, Kunert G, Lavista-Llanos S, Valenzano DR, Rybak J, Barrett B, Knaden M, Hansson B (2019).Inverse resource allocation between vision and olfaction across the genus Drosophila.Nat Commun.2019 Mar 11;10(1):1162. doi: 10.1038/s41467-019-09087-z

Silvia von Karstedt

  • Mert U, Adawy A, Scharff E, Teichmann P, Willms A, Haselmann V, Colmorgen C, Lemke J, von Karstedt S, Fritsch J, Trauzold A (2019). TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors. Cancers (BASEL). 2019 Aug 14;11(8). pii: E1167. doi: 10.3390/cancers11081167
  • Heilmann T, Vondung F, Borzikowsky C, Szymczak S, Krüger S, Alkatout I, Wenners A, Bauer M, Klapper W, Röcken C, Maass N, von Karstedt S, Schem C, Trauzold A (2019). Heterogeneous intracellular TRAIL-receptor distribution predicts poor outcome in breast cancer patients. J Mol Med (Berl). 2019 Aug;97(8):1155-1167. doi:10.1007/s00109-019-01805-w. Epub 2019 Jun 10         
  • Lim JKM, Delaidelli A, Minaker SW, Zhang HF, Colovic M, Yang H, Negri GL, von Karstedt S, Lockwood WW, Schaffer P, Leprivier G, Sorensen PH (2019). Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9433-9442. doi:10.1073/pnas.1821323116. Epub 2019 Apr 18           
  • Kretz AL, Trauzold A, Hillenbrand A, Knippschild U, Henne-Bruns D, von Karstedt S, Lemke J (2019). TRAILblazing Strategies for Cancer Treatment. Cancers (Basel). 2019 Mar 30;11(4). pii: E456. doi:10.3390/cancers11040456. Review.