Publications 2021

A B C​​​​​​ D E F G​​​​​​ H I J​​​​​​​ K​​​​​​​ L​​​​​​​ M N O P​​​​​​​ Q​​​​​​​ R​​​​​​​ S​​​​​​​ T​​​​​​​ U​​​​​​​ V​​​​​​​ W​​​​​​​ X​​​​​​​ Y​​​​​​​ Z​​​​​​​​​​​​​​​​​​​​​

Adam Antebi

  • Schiffer I, Gerisch B, Kawamura K, Laboy R, Hewitt J, Denzel MS, Mori MA, Vanapalli S, Shen Y, Symmons O, Antebi A(2021). miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging. Elife. 2021 Jul 27;10:e66768. doi: 10.7554/eLife.66768. PMID: 34311841; PMCID: PMC8315803. 
  • Ellwood RA, Hewitt JE, Torregrossa R, Philp AM, Hardee JP, Hughes S, van de Klashorst D, Gharahdaghi N, Anupom T, Slade L, Deane CS, Cooke M, Etheridge T, Piasecki M, Antebi A, Lynch GS, Philp A, Vanapalli SA, Whiteman M, Szewczyk NJ (2021). Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2018342118. doi: 10.1073/pnas.2018342118. PMID: 33627403
  • Allmeroth K, Kim CS, Annibal A, Pouikli A, Koester J, Derisbourg MJ, Andrés Chacón-Martínez C, Latza C, Antebi A, Tessarz P, Wickström SA, Denzel MS. N1-acetylspermidine is a determinant of hair follicle stem cell fate. J Cell Sci. 2021 May 1;134(9):jcs252767. doi: 10.1242/jcs.252767. Epub 2021 May 11. PMID: 33973637. 
  • Annibal A, Tharyan RG, Schonewolff MF, Tam H, Latza C, Auler MMK, Grönke S, Partridge L, Antebi A(2021). Author Correction: Regulation of the one carbon folate cycle as a shared metabolic signature of longevity. Nat Commun. 2021 Aug 12;12(1):5025. doi: 10.1038/s41467-021-24840-z. Erratum for: Nat Commun. 2021 Jun 9;12(1):3486. PMID: 34385439; PMCID: PMC8361093. 
  • Dolfi L, Suen TK, Ripa R, Antebi A (2021). Sperm cryopreservation and in vitro fertilization techniques for the African turquoise killifish Nothobranchius furzeri. Sci Rep. 2021 Aug 25;11(1):17145. doi: 10.1038/s41598-021-96383-8. PMID: 34433853.
  • Annibal A, Ripa R, Ballhysa E, Latza C, Hochhard N, Antebi A (2021). Mass spectrometric characterization of cyclic dinucleotides (CDNs) in vivo. Anal Bioanal Chem. 2021 Sep 2:1-12. doi: 10.1007/s00216-021-03628-6. Online ahead of print. PMID: 34476522
  • Lengefeld J, Cheng CW, Maretich P, Blair M, Hagen H, McReynolds MR, Sullivan E, Majors K, Roberts C, Kang JH, Steiner JD, Miettinen TP, Manalis SR, Antebi A, Morrison SJ, Lees JA, Boyer LA, Yilmaz ÖH, Amon A (2021). Cell size is a determinant of stem cell potential during aging.Sci Adv. 2021 Nov 12;7(46):eabk0271. doi: 10.1126/sciadv.abk0271. Epub 2021 Nov 12. PMID: 34767451 

Miguel A. Alejandre Alcazar

  • Voggel J, Mohr J, Nüsken KD, Dötsch J, Nüsken E, Alcazar MA (2021). Translational insights into mechanisms and preventive strategies after renal injury in neonates. Semin Fetal Neonatal Med. 2021 May 8:101245. doi: 10.1016/j.siny.2021.101245. Epub ahead of print. PMID: 33994314. 
  • Kuiper-Makris C, Selle J, Nüsken E, Dötsch J, Alejandre Alcazar MA. Perinatal Nutritional and Metabolic Pathways: Early Origins of Chronic Lung Diseases. Front Med (Lausanne). 2021 Jun 15;8:667315. doi: 10.3389/fmed.2021.667315. PMID: 34211985; PMCID: PMC8239134.
  • Hirani D, Alvira CM, Danopoulos S, Milla C, Donato M, Tian L, Mohr J, Dinger K, Vohlen C, Selle J, Koningsbruggen-Rietschel SV, Barbarino V, Pallasch C, Rose-John S, Odenthal M, Pryhuber GS, Mansouri S, Savai R, Seeger W, Khatri P, Al Alam D, Dötsch J, Alejandre Alcazar MA (2021). Macrophage-derived IL-6 trans-signaling as a novel target in the pathogenesis of bronchopulmonary dysplasia. Eur Respir J. 2021 Aug 26:2002248. doi: 10.1183/13993003.02248-2020. Online ahead of print. PMID: 34446466
  • Vohlen C, Mohr J, Fomenko A, Kuiper-Makris C, Grzembke T, Aydogmus R, Wilke R, Hirani D, Dötsch J, Alejandre Alcazar MA (2021). Dynamic Regulation of GH-IGF1 Signaling in Injury and Recovery in Hyperoxia-Induced Neonatal Lung Injury. Cells. 2021 Oct 29;10(11):2947. doi: 10.3390/cells10112947.PMID: 34831169
  • Thomassen JC, Trojan T, Lippach G, Rietschel E, Alejandre Alcázar MA*, van Koningsbruggen-Rietschel S* (2021). Inflammatory markers in sputum - P. aeruginosa is an important trigger of airway inflammation in cystic fibrosis. European Respiratory Journal (ERJ) Open Res. 2021 Jul 19;7(3):00636-2020. doi: 10.1183/23120541.00636-2020.  *shared last authorship. PMID: 34291109
  • Berghausen E, Janssen W, Vantler M, Behringer B, Joseph C, Zierden M, ten Freyhaus H, Klinke A, Baldus S, Alejandre Alcázar M.A., Savai R, Pullamsetti S, Zhao J, Schermuly R, Rosenkranz S (2021). p110α is a Central Target in Pulmonary Hypertension. Journal of Clinical Investigation (JCI). 2021 Oct 1;131(19):e136939. doi: 10.1172/JCI136939. PMID: 34596056

Hisham Bazzi

  • Phan TP, Maryniak AL, Boatwright CA, Lee J, Atkins A, Tijhuis A, Spierings DC, Bazzi H, Foijer F, Jordan PW, Stracker TH, Holland AJ (2021). Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway. EMBO J. 2021 Jan 4;40(1):e106118. doi: 10.15252/embj.2020106118. Epub 2020 Nov 23   
  • Xiao C, Grzonka M, Meyer-Gerards C, Mack M, Figge R, Bazzi H (2021). Gradual centriole maturation associates with the mitotic surveillance pathway in mouse development. EMBO Rep. 2021 Jan 7:e51127. doi: 10.15252/embr.202051127. Online ahead of print. PMID: 33410253 
  • Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H (2021). High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227. doi: 10.1038/s41467-021-23386-4. PMID: 34050161; PMCID: PMC8163813. 
  • Crispatzu G, Rehimi R, Pachano T, Bleckwehl T, Cruz-Molina S, Xiao C, Mahabir E, Bazzi H, Rada-Iglesias A (2021). The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo. Nat Commun. 2021 Jul 16;12(1):4344. doi: 10.1038/s41467-021-24641-4. PMID: 34272393; PMCID: PMC8285398.

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Thomas Benzing

  • Pickert L, Meyer AM, Becker I, Heeß A, Noetzel N, Brinkkötter P, Pilotto A, Benzing T, Polidori MC (2021). Role of a multidimensional prognosis in-hospital monitoring for older patients with prolonged stay. Int J Clin Pract. 2021 Jan 6:e13989. doi: 10.1111/ijcp.13989. Online ahead of print. PMID: 33406298 
  • Polidori MC, Sies H, Ferrucci L, Benzing T (2021). COVID-19 mortality as a fingerprint of biological age. Ageing Res Rev. 2021 May;67:101308. doi: 10.1016/j.arr.2021.101308. Epub 2021 Feb 20. PMID: 33621704; PMCID: PMC7896489. 
  • Benzing T, Salant D (2021). Insights into Glomerular Filtration and Albuminuria. N Engl J Med. 2021 Apr 15;384(15):1437-1446. doi: 10.1056/NEJMra1808786. PMID: 33852781.
  • Talyan S, Filipów S, Ignarski M, Smieszek M, Chen H, Kühne L, Butt L, Göbel H, Hoyer-Allo KJR, Koehler FC, Altmüller J, Brinkkötter P, Schermer B, Benzing T, Kann M, Müller RU, Dieterich C. CALINCA-A Novel Pipeline for the Identification of lncRNAs in Podocyte Disease. Cells. 2021 Mar 20;10(3):692. doi: 10.3390/cells10030692. PMID: 33804736; PMCID: PMC8003990.
  • He B, Chen P, Zambrano S, Dabaghie D, Hu Y, Möller-Hackbarth K, Unnersjö-Jess D, Korkut GG, Charrin E, Jeansson M, Bintanel-Morcillo M, Witasp A, Wennberg L, Wernerson A, Schermer B, Benzing T, Ernfors P, Betsholtz C, Lal M, Sandberg R, Patrakka J. Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes. Nat Commun. 2021 Apr 9;12(1):2141. doi: 10.1038/s41467-021-22331-9. PMID: 33837218; PMCID: PMC8035407. 
  • Hoyer-Allo KJR, Späth MR, Hanssen R, Johnsen M, Brodesser S, Kaufmann K, Kiefer K, Koehler FC, Göbel H, Kubacki T, Grundmann F, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2021). Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury. Int J Mol Sci. 2021 May 22;22(11):5485. doi: 10.3390/ijms22115485. PMID: 34067475; PMCID: PMC8196977. 
  • Lagolio E, Demurtas J, Buzzetti R, Cortassa G, Bottone S, Spadafora L, Cocino C, Smith L, Benzing T, Polidori MC (2021). A rapid and feasible tool for clinical decision making in community-dwelling patients with COVID-19 and those admitted to emergency departments: the Braden-LDH-HorowITZ Assessment-BLITZ. Intern Emerg Med. 2021 Jul 28:1–6. doi: 10.1007/s11739-021-02805-w. Epub ahead of print. PMID: 34322832; PMCID: PMC8318055.
  • Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B (2021). Maintaining proteostasis under mechanical stress. EMBO Rep. 2021 Aug 4;22(8):e52507. doi: 10.15252/embr.202152507. Epub 2021 Jul 26. PMID: 34309183. 
  • Butt L, Unnersjö-Jess D, Höhne M, Schermer B, Edwards A, Benzing T (2021). A mathematical estimation of the physical forces driving podocyte detachment. Kidney Int. 2021 Jul 29:S0085-2538(21)00728-6. doi: 10.1016/j.kint.2021.06.040. Epub ahead of print. PMID: 34332959.
  • Mangold N, Pippin J, Unnersjoe-Jess D, Koehler S, Shankland S, Brähler S, Schermer B, Benzing T,Brinkkoetter PT, Hagmann H (2021). The Atypical Cyclin-Dependent Kinase 5 (Cdk5) Guards Podocytes from Apoptosis in Glomerular Disease While Being Dispensable for Podocyte Development. Cells. 2021 Sep 18;10(9):2464. doi: 10.3390/cells10092464. PMID: 34572114.
  • Kühne L, Völker LA, Hagmann H, Hägele H, Osterholt T, Eichenauer DA, Thomas A, Breuer J, Grüttner B, Gottschalk I, Kann M, Benzing T, Thevis M, Müller AM, Brinkkoetter PT (2021). First use of the anti-VWF nanobody caplacizumab to treat iTTP in pregnancy. Br J Haematol. 2021 Sep 29. doi: 10.1111/bjh.17833. Online ahead of print. PMID: 34585743 
  • Heeß A, Meyer AM, Becker I, Noetzel N, Verleysdonk J, Rarek M, Benzing T, Polidori MC (2021). The prognostic fingerprint of quality of life in older inpatients : Relationship to geriatric syndromes' and resources' profile. Z Gerontol Geriatr. 2021 Oct 6. doi: 10.1007/s00391-021-01978-5. Online ahead of print. PMID: 34617144 
  • Noetzel N, Meyer AM, Siri G, Pickert L, Heeß A, Verleysdonk J, Benzing T, Pilotto A, Barbe AG, Polidori MC (2021). The impact of oral health on prognosis of older multimorbid inpatients: the 6-month follow up MPI oral health study (MPIOH). Eur Geriatr Med. 2021 Apr;12(2):263-273. doi: 10.1007/s41999-020-00427-7. Epub 2020 Nov 18. PMID: 33206351
  • Seufert L, Benzing T, Ignarski M, Müller RU (2021). RNA-binding proteins and their role in kidney disease.Nat Rev Nephrol. 2021 Nov 3. doi: 10.1038/s41581-021-00497-1. Online ahead of print. PMID: 34732838
  • Reusch B, Bartram MP, Dafinger C, Palacio-Escat N, Wenzel A, Fenton RA, Saez-Rodriguez J, Schermer B, Benzing T, Altmüller J, Beck BB, Rinschen MM (2021). MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells. J Proteomics. 2021 Nov 11:104424. doi: 10.1016/j.jprot.2021.104424. Online ahead of print. PMID: 34775100
  • Höhfeld J., Benzing T., Bloch, W. Fürst D.O., Gehlert S., Hesse M., Hoffmann B., Hoppe T., Huesgen P.F., Köhn M., Kolanus W., Merkel R., NIessen C.M., Pokrzywa W., Rinschen M.M., Wachten D., Warscheid B. (2021). Maintaining proteostasis under mechanical stress. EMBO Rep. 2021 Aug 4;22(8):e52507. doi: 10.15252/embr.202152507.Epub 2021 Jul 26.
  • Affeldt P, Koehler FC, Brensing KA, Adam V, Burian J, Butt L, Gies M, Grundmann F, Hinrichs S, Johannis W, Kalisch N, Meyer-Delpho M, Oehm S, Platen E, Schöler C, Heger E, Steger G, Stippel D, Ziegelhöfer A, Benzing T, Klein F, Kurschat C, Müller R-U*, Cristanziano VD(2021). Immune Responses to SARS-CoV-2 Infection and Vaccination in Dialysis Patients and Kidney Transplant Recipients. Microorganisms. 2022; 10(1):4. https://doi.org/10.3390/microorganisms10010004
  • Koehler S, Odenthal J, Ludwig V, Jess DU, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HHH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T,Iden S, Brinkkoetter PT(2021). Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int. 2021 Dec 17:S0085-2538(21)01150-9. doi: 10.1016/j.kint.2021.11.030. Epub ahead of print. PMID: 34929254.

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Matteo Bergami

  • Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC Jr, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR Jr, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cantí C, Cao B, Caraglia M, Caramés B, Carchman EH, Cardenal-Muñoz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carosi JM, Carra S, Carrier A, Carrier L, Carroll B, Carter AB, Carvalho AN, Casanova M, Casas C, Casas J, Cassioli C, Castillo EF, Castillo K, Castillo-Lluva S, Castoldi F, Castori M, Castro AF, Castro-Caldas M, Castro-Hernandez J, Castro-Obregon S, Catz SD, Cavadas C, Cavaliere F, Cavallini G, Cavinato M, Cayuela ML, Cebollada Rica P, Cecarini V, Cecconi F, Cechowska-Pasko M, Cenci S, Ceperuelo-Mallafré V, Cerqueira JJ, Cerutti JM, Cervia D, Cetintas VB, Cetrullo S, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chakrabarti O, Chakraborty T, Chakraborty T, Chami M, Chamilos G, Chan DW, Chan EYW, Chan ED, Chan HYE, Chan HH, Chan H, Chan MTV, Chan YS, Chandra PK, Chang CP, Chang C, Chang HC, Chang K, Chao J, Chapman T, Charlet-Berguerand N, Chatterjee S, Chaube SK, Chaudhary A, Chauhan S, Chaum E, Checler F, Cheetham ME, Chen CS, Chen GC, Chen JF, Chen LL, Chen L, Chen L, Chen M, Chen MK, Chen N, Chen Q, Chen RH, Chen S, Chen W, Chen W, Chen XM, Chen XW, Chen X, Chen Y, Chen YG, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen ZS, Chen Z, Chen ZH, Chen ZJ, Chen Z, Cheng H, Cheng J, Cheng SY, Cheng W, Cheng X, Cheng XT, Cheng Y, Cheng Z, Chen Z, Cheong H, Cheong JK, Chernyak BV, Cherry S, Cheung CFR, Cheung CHA, Cheung KH, Chevet E, Chi RJ, Chiang AKS, Chiaradonna F, Chiarelli R, Chiariello M, Chica N, Chiocca S, Chiong M, Chiou SH, Chiramel AI, Chiurchiù V, Cho DH, Choe SK, Choi AMK, Choi ME, Choudhury KR, Chow NS, Chu CT, Chua JP, Chua JJE, Chung H, Chung KP, Chung S, Chung SH, Chung YL, Cianfanelli V, Ciechomska IA, Cifuentes M, Cinque L, Cirak S, Cirone M, Clague MJ, Clarke R, Clementi E, Coccia EM, Codogno P, Cohen E, Cohen MM, Colasanti T, Colasuonno F, Colbert RA, Colell A, Čolić M, Coll NS, Collins MO, Colombo MI, Colón-Ramos DA, Combaret L, Comincini S, Cominetti MR, Consiglio A, Conte A, Conti F, Contu VR, Cookson MR, Coombs KM, Coppens I, Corasaniti MT, Corkery DP, Cordes N, Cortese K, Costa MDC, Costantino S, Costelli P, Coto-Montes A, Crack PJ, Crespo JL, Criollo A, Crippa V, Cristofani R, Csizmadia T, Cuadrado A, Cui B, Cui J, Cui Y, Cui Y, Culetto E, Cumino AC, Cybulsky AV, Czaja MJ, Czuczwar SJ, D'Adamo S, D'Amelio M, D'Arcangelo D, D'Lugos AC, D'Orazi G, da Silva JA, Dafsari HS, Dagda RK, Dagdas Y, Daglia M, Dai X, Dai Y, Dai Y, Dal Col J, Dalhaimer P, Dalla Valle L, Dallenga T, Dalmasso G, Damme M, Dando I, Dantuma NP, Darling AL, Das H, Dasarathy S, Dasari SK, Dash S, Daumke O, Dauphinee AN, Davies JS, Dávila VA, Davis RJ, Davis T, Dayalan Naidu S, De Amicis F, De Bosscher K, De Felice F, De Franceschi L, De Leonibus C, de Mattos Barbosa MG, De Meyer GRY, De Milito A, De Nunzio C, De Palma C, De Santi M, De Virgilio C, De Zio D, Debnath J, DeBosch BJ, Decuypere JP, Deehan MA, Deflorian G, DeGregori J, Dehay B, Del Rio G, Delaney JR, Delbridge LMD, Delorme-Axford E, Delpino MV, Demarchi F, Dembitz V, Demers ND, Deng H, Deng Z, Dengjel J, Dent P, Denton D, DePamphilis ML, Der CJ, Deretic V, Descoteaux A, Devis L, Devkota S, Devuyst O, Dewson G, Dharmasivam M, Dhiman R, di Bernardo D, Di Cristina M, Di Domenico F, Di Fazio P, Di Fonzo A, Di Guardo G, Di Guglielmo GM, Di Leo L, Di Malta C, Di Nardo A, Di Rienzo M, Di Sano F, Diallinas G, Diao J, Diaz-Araya G, Díaz-Laviada I, Dickinson JM, Diederich M, Dieudé M, Dikic I, Ding S, Ding WX, Dini L, Dinić J, Dinic M, Dinkova-Kostova AT, Dionne MS, Distler JHW, Diwan A, Dixon IMC, Djavaheri-Mergny M, Dobrinski I, Dobrovinskaya O, Dobrowolski R, Dobson RCJ, Đokić J, Dokmeci Emre S, Donadelli M, Dong B, Dong X, Dong Z, Dorn Ii GW, Dotsch V, Dou H, Dou J, Dowaidar M, Dridi S, Drucker L, Du A, Du C, Du G, Du HN, Du LL, du Toit A, Duan SB, Duan X, Duarte SP, Dubrovska A, Dunlop EA, Dupont N, Durán RV, Dwarakanath BS, Dyshlovoy SA, Ebrahimi-Fakhari D, Eckhart L, Edelstein CL, Efferth T, Eftekharpour E, Eichinger L, Eid N, Eisenberg T, Eissa NT, Eissa S, Ejarque M, El Andaloussi A, El-Hage N, El-Naggar S, Eleuteri AM, El-Shafey ES, 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CS, Li Z, Lin Y, Oshima S, Rong Y, Sluimer JC, Stallings CL, Tong CK. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. PMID: 33634751; PMCID: PMC7996087.

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Andreas Beyer

  • Lackner A, Sehlke R, Garmhausen M, Giuseppe Stirparo G, Huth M, Titz-Teixeira F, van der Lelij P, Ramesmayer J, Thomas HF, Ralser M, Santini L, Galimberti E, Sarov M, Stewart AF, Smith A, Beyer A, Leeb M (2021). Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency. EMBO J. 2021 Mar 9:e105776. doi: 10.15252/embj.2020105776. Online ahead of print. PMID: 33687089
  • Tain LS, Sehlke R, Meilenbrock RL, Leech T, Paulitz J, Chokkalingam M, Nagaraj N, Grönke S, Fröhlich J, Atanassov I, Mann M, Beyer A, Partridge L. Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila. Elife. 2021 Apr 21;10:e67275. doi: 10.7554/eLife.67275. PMID: 33879316; PMCID: PMC8060030.
  • Tognetti M, Gabor A, Yang M, Cappelletti V, Windhager J, Rueda OM, Charmpi K, Esmaeilishirazifard E, Bruna A, de Souza N, Caldas C, Beyer A, Picotti P, Saez-Rodriguez J, Bodenmiller B. Deciphering the signaling network of breast cancer improves drug sensitivity prediction. Cell Syst. 2021 Apr 27:S2405-4712(21)00111-3. doi: 10.1016/j.cels.2021.04.002. Epub ahead of print. PMID: 33932331.
  • He F, Steige KA, Kovacova V, Göbel U, Bouzid M, Keightley PD, Beyer A, de Meaux J (2021). Cis-regulatory evolution spotlights species differences in the adaptive potential of gene expression plasticity. Nat Commun. 2021 Jun 7;12(1):3376. doi: 10.1038/s41467-021-23558-2. PMID: 34099660; PMCID: PMC8184852. 
  • Santini L, Halbritter F, Titz-Teixeira F, Suzuki T, Asami M, Ma X, Ramesmayer J, Lackner A, Warr N, Pauler F, Hippenmeyer S, Laue E, Farlik M, Bock C, Beyer A, Perry ACF, Leeb M (2021). Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3. Nat Commun. 2021 Jun 21;12(1):3804. doi: 10.1038/s41467-021-23510-4. PMID: 34155196.
  • Charmpi K, Chokkalingam M, Johnen R, Beyer A (2021). Optimizing network propagation for multi-omics data integration. PLoS Comput Biol. 2021 Nov 11;17(11):e1009161. doi: 10.1371/journal.pcbi.1009161. Online ahead of print. PMID: 34762640
  • Cappelletti V, Hauser T, Piazza I, Pepelnjak M, Malinovska L, Fuhrer T, Li Y, Dörig C, Boersema P, Gillet L, Grossbach J, Dugourd A, Saez-Rodriguez J, Beyer A, Zamboni N, Caflisch A, de Souza N, Picotti P (2021). Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ. Cell (20)31691-3. doi: 10.1016/j.cell.2020.12.021. PMID: 33357446

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Jens Brüning  

  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798
  • Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC(2021). Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat Neurosci. 2021 May 17. doi: 10.1038/s41593-021-00854-0. Epub ahead of print. PMID: 34002087.
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning JC, Langer T, Braun T, Krüger M (2021).Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. Feb 5;154:41-59. doi: 10.1016/j.yjmcc.2021.01.010.Online ahead of print.
  • Hanssen, R, Kretschmer AC, Rigoux L, Albus K, Edwin Thanarajah S, Sitnikow T, Melzer C, Cornely OA, Brüning JC, Tittgemeyer M (2021). GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans. Mol Metab. Jan 14;45:101163. doi: 10.1016/j.molmet.2021.101163. Online ahead of print 
  • Dodd GT, Kim SJ, Méquinion M, Xirouchaki CE, Brüning JC, Andrews ZB, Tiganis T (2021). Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance. Sci Adv. 2021 Feb 26;7(9):eabf4100. doi: 10.1126/sciadv.abf4100. Print 2021 Feb. PMID: 33637536 
  • Quarta C, Claret M, Zeltser LM, Williams KW, Yeo GSH, Tschöp MH, Diano S, Brüning JC, Cota D (2021). POMC neuronal heterogeneity in energy balance and beyond: an integrated view. Nat Metab. 2021 Feb 25. doi: 10.1038/s42255-021-00345-3. Online ahead of print. PMID: 33633406 Review. 
  • Borgmann D, Ciglieri E, Biglari N, Brandt C, Cremer AL, Backes H, Tittgemeyer M, Wunderlich FT, Brüning JC, Fenselau H (2021). Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metab. 2021 May 21:S1550-4131(21)00219-9. doi: 10.1016/j.cmet.2021.05.002. Epub ahead of print. PMID: 34043943.
  • Hoyer-Allo KJR, Späth MR, Hanssen R, Johnsen M, Brodesser S, Kaufmann K, Kiefer K, Koehler FC, Göbel H, Kubacki T, Grundmann F, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2021). Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury. Int J Mol Sci. 2021 May 22;22(11):5485. doi: 10.3390/ijms22115485. PMID: 34067475; PMCID: PMC8196977.
  • Jais A, Brüning JC (2021). Arcuate nucleus-dependent regulation of metabolism - pathways to obesity and diabetes mellitus. Endocr Rev. 2021 Sep 7: bnab025. doi: 10.1210/endrev/bnab025. Online ahead of print. PMID: 34490882
  • Xiao X, Yeghiazaryan G, Hess S, Klemm P, Sieben A, Kleinridders A, Morgan DA, Wunderlich FT, Rahmouni K, Kong D, Scammell TE, Lowell BB, Kloppenburg P, Brüning JC, Hausen AC (2021). Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity. Nat Commun. 2021 Sep 2;12(1):5249. doi: 10.1038/s41467-021-25380-2. PMID: 34475397
  • Willenborg S, Sanin DE, Jais A, Ding X, Ulas T, Nüchel J, Popović M, MacVicar T, Langer T, Schultze JL, Gerbaulet A, Roers A, Pearce EJ, Brüning JC, Trifunovic A, Eming SA (2021). Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab. 2021 Oct 25:S1550-4131(21)00482-4. doi: 10.1016/j.cmet.2021.10.004. Online ahead of print. PMID: 34715039

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Filipe Cabreiro

  • Klünemann M, Andrejev S, Blasche S, Mateus A, Phapale P, Devendran S, Vappiani J, Simon B, Scott TA, Kafkia E, Konstantinidis D, Zirngibl K, Mastrorilli E, Banzhaf M, Mackmull MT, Hövelmann F, Nesme L, Brochado AR, Maier L, Bock T, Periwal V, Kumar M, Kim Y, Tramontano M, Schultz C, Beck M, Hennig J, Zimmermann M, Sévin DC, Cabreiro F, Savitski MM, Bork P, Typas A, Patil KR (2021). Bioaccumulation of therapeutic drugs by human gut bacteria. Nature. 2021 Sep 8. doi: 10.1038/s41586-021-03891-8. Online ahead of print. PMID: 34497420
  • Martinez-Miguel VE, Lujan C, Espie-Caullet T, Martinez-Martinez D, Moore S, Backes C, Gonzalez S, Galimov ER, Brown AEX, Halic M, Tomita K, Rallis C, von der Haar T, Cabreiro F, Bjedov I (2021). Increased fidelity of protein synthesis extends lifespan. Cell Metab. 2021 Sep 8: S1550-4131(21)00417-4. doi: 10.1016/j.cmet.2021.08.017. Online ahead of print. PMID: 34525330

Oliver Cornely

  • Koehler P, Cornely OA, Kochanek M (2021). Bronchoscopy safety precautions for diagnosing COVID-19 associated pulmonary aspergillosis-A simulation study. Mycoses. 2021 Jan;64(1):55-59. doi: 10.1111/myc.13183. Epub 2020 Sep 26. PMID: 32918497
  • Budin S, Salmanton-García J, Koehler P, Stemler J, Cornely OA, Mellinghoff SC (2021). Validation of the EQUAL Aspergillosis Score by analysing guideline-adherent management of invasive pulmonary aspergillosis. J Antimicrob Chemother. 2021 Jan 4:dkaa518. doi: 10.1093/jac/dkaa518. Online ahead of print. PMID: 33394007
  • Chen SC, Halliday CL, Hoenigl M, Cornely OA, Meyer W (2021). Scedosporium and LomentosporaInfections: Contemporary Microbiological Tools for the Diagnosis of Invasive Disease. J Fungi (Basel). 2021 Jan 4;7(1):E23. doi: 10.3390/jof7010023. PMID: 33406673 Review.
  • van Werkhoven CH, Ducher A, Berkell M, Mysara M, Lammens C, Torre-Cisneros J, Rodríguez-Baño J, Herghea D, Cornely OA, Biehl LM, Bernard L, Dominguez-Luzon MA, Maraki S, Barraud O, Nica M, Jazmati N, Sablier-Gallis F, de Gunzburg J, Mentré F, Malhotra-Kumar S, Bonten MJM, Vehreschild MJGT; ANTICIPATE Study Group. Incidence and predictive biomarkers of Clostridioides difficile infection in hospitalized patients receiving broad-spectrum antibiotics. Nat Commun. 2021 Apr 14;12(1):2240. doi: 10.1038/s41467-021-22269-y. PMID: 33854064.
  • Hanssen R, Kretschmer AC, Rigoux L, Albus K, Thanarajah SE, Sitnikow T, Melzer C, Cornely OA, Brüning JC, Tittgemeyer M (2021). GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans. Mol Metab. 2021 Jan 13:101163. doi: 10.1016/j.molmet.2021.101163. Online ahead of print. PMID: 33453418
  • Christopeit M, Schmidt-Hieber M, Sprute R, Buchheidt D, Hentrich M, Karthaus M, Penack O, Ruhnke M, Weissinger F, Cornely OA, Maschmeyer G (2021). Prophylaxis, diagnosis and therapy of infections in patients undergoing high-dose chemotherapy and autologous haematopoietic stem cell transplantation. 2020 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO). Ann Hematol. 2021 Feb;100(2):321-336. doi: 10.1007/s00277-020-04297-8. Epub 2020 Oct 20. PMID: 33079221
  • Wunsch S, Zurl C, Strohmaier H, Meinitzer A, Rabensteiner J, Posch W, Lass-Flörl C, Cornely O, Pregartner G, König E, Feierl G, Hoenigl M, Prattes J, Zollner-Schwetz I, Valentin T, Krause R (2021). Longitudinal Evaluation of Plasma Cytokine Levels in Patients with Invasive Candidiasis. J Fungi (Basel).2021 Feb 1;7(2):101. doi: 10.3390/jof7020101. PMID: 33535593
  • Banck JC, Mueller N, Mellinghoff SC, Thelen M, Fraccaroli A, Blumenberg V, Koehler P, Kunz WG, Rudelius M, Schrötzlmair F, Subklewe M, Schlößer HA, Tischer J, Cornely OA, Lindner LH, von Bergwelt-Baildon M (2021). Immune Checkpoint Blockade for Aspergillosis and Mucormycosis Coinfection. Hemasphere. 2021 Feb 10;5(3):e530. doi: 10.1097/HS9.0000000000000530. eCollection 2021 Mar. PMID: 33604513
  • Hoenigl M, Levitz SM, Schuetz AN, Zhang SX, Cornely OA (2021). All You Need to Know and More about the Diagnosis and Management of Rare Mold Infections. mBio. 2021 Feb 23;12(1):e02920-20. doi: 10.1128/mBio.02920-20. PMID: 33622731
  • Sprute R, Seidel D, Cornely OA, Hoenigl M (2021). EHA Endorsement of the Global Guideline for the Diagnosis and Management of Rare Mold Infection: An Initiative of the European Confederation of Medical Mycology in Cooperation With International Society for Human and Animal Mycology and American Society for Microbiology. Hemasphere. 2021 Feb 23;5(3):e519. doi: 10.1097/HS9.0000000000000519. eCollection 2021 Mar. PMID: 33644696 No abstract available
  • Giesen N, Sprute R, Rüthrich M, Khodamoradi Y, Mellinghoff SC, Beutel G, Lueck C, Koldehoff M, Hentrich M, Sandherr M, von Bergwelt-Baildon M, Wolf HH, Hirsch HH, Wörmann B, Cornely OA, Köhler P, Schalk E, von Lilienfeld-Toal M; COVID-19 guideline panel of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO) (2021). 2021 update of the AGIHO guideline on evidence-based management of COVID-19 in patients with cancer regarding diagnostics, viral shedding, vaccination and therapy. Eur J Cancer. 2021 Feb 10;147:154-160. doi: 10.1016/j.ejca.2021.01.033. Online ahead of print. PMID: 33676266
  • Meinberger D, Koch M, Roth A, Hermes G, Stemler J, Cornely OA, Streichert T, Klatt AR. Analysis of IgM, IgA, and IgG isotype antibodies Directed against SARS-CoV-2 spike glycoprotein and ORF8 in the course of COVID-19. Sci Rep. 2021 Apr 26;11(1):8920. doi: 10.1038/s41598-021-88356-8. PMID: 33903660; PMCID: PMC8076237. 
  • Classen AY, Henze L, von Lilienfeld-Toal M, Maschmeyer G, Sandherr M, Graeff LD, Alakel N, Christopeit M, Krause SW, Mayer K, Neumann S, Cornely OA, Penack O, Weißinger F, Wolf HH, Vehreschild JJ (2021).Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematologic malignancies and solid tumors: 2020 updated guidelines of the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology (AGIHO/DGHO). Ann Hematol. 2021 Jun;100(6):1603-1620. doi: 10.1007/s00277-021-04452-9. Epub 2021 Apr 13. PMID: 33846857; PMCID: PMC8116237. 
  • Stemler J, Cornely OA, Noack-Schönborn T, Fohrholz C, Schumacher S, Poluschkin L, Binder B, Lehmann C, Langebartels G (2021). Web-based, rapid and contactless management of ambulatory patients for SARS-CoV-2-testing. BMC Infect Dis. 2021 Jun 7;21(1):535. doi: 10.1186/s12879-021-06249-7. PMID: 34098882; PMCID: PMC8182346.
  • Rudramurthy SM, Hoenigl M, Meis JF, Cornely OA, Muthu V, Gangneux JP, Perfect J, Chakrabarti A; ECMM and ISHAM (2021). ECMM/ISHAM recommendations for clinical management of COVID -19 associated mucormycosis in low- and middle-income countries. Mycoses. 2021 Jun 16. doi: 10.1111/myc.13335. Epub ahead of print. PMID: 34133816. 
  • Verweij PE, Brüggemann RJM, Azoulay E, Bassetti M, Blot S, Buil JB, Calandra T, Chiller T, Clancy CJ, Cornely OA, Depuydt P, Koehler P, Lagrou K, de Lange D, Lass-Flörl C, Lewis RE, Lortholary O, Liu PL, Maertens J, Nguyen MH, Patterson TF, Rijnders BJA, Rodriguez A, Rogers TR, Schouten JA, Wauters J, van de Veerdonk FL, Martin-Loeches I (2021). Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis. Intensive Care Med. 2021 Jun 23:1–16. doi: 10.1007/s00134-021-06449-4. Epub ahead of print. PMID: 34160631; PMCID: PMC8220883. 
  • Koehler P, Bassetti M, Chakrabarti A, Chen SCA, Colombo AL, Hoenigl M, Klimko N, Lass-Flörl C, Oladele RO, Vinh DC, Zhu LP, Böll B, Brüggemann R, Gangneux JP, Perfect JR, Patterson TF, Persigehl T, Meis JF, Ostrosky-Zeichner L, White PL, Verweij PE, Cornely OA; European Confederation of Medical Mycology; International Society for Human Animal Mycology; Asia Fungal Working Group; INFOCUS LATAM/ISHAM Working Group; ISHAM Pan Africa Mycology Working Group; European Society for Clinical Microbiology; Infectious Diseases Fungal Infection Study Group; ESCMID Study Group for Infections in Critically Ill Patients; Interregional Association of Clinical Microbiology and Antimicrobial Chemotherapy; Medical Mycology Society of Nigeria; Medical Mycology Society of China Medicine Education Association; Infectious Diseases Working Party of the German Society for Haematology and Medical Oncology; Association of Medical Microbiology; Infectious Disease Canada (2021). Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance. Lancet Infect Dis. 2021 Jun;21(6):e149-e162. doi: 10.1016/S1473-3099(20)30847-1. Epub 2020 Dec 14. PMID: 33333012; PMCID: PMC7833078. 
  • Groll AH, Gordon K, Buchheidt D, Willinger B, Heinz WJ, Kurzai O, Rickerts V, Cornely OA; Medical Mycology at German Academic Medical Centers (MMGAMC) Study Group (2021). State of Medical Mycology at German Academic Medical Centres: A Survey of the German-Speaking Mycological Society (DMYKG) and the Paul-Ehrlich-Society for Chemotherapy (PEG). Mycoses. 2021 Jun 27. doi: 10.1111/myc.13346. Epub ahead of print. PMID: 34180098. 
  • Salmanton-García J, Busca A, Cornely OA, Corradini P, Hoenigl M, Klimko N, Marchesi F, Pagliuca A, Passamonti F, Koehler P, Pagano L (2021). EPICOVIDEHA: A Ready to Use Platform for Epidemiological Studies in Hematological Patients With COVID-19. Hemasphere. 2021 Jun 25;5(7):e612. doi: 10.1097/HS9.0000000000000612. PMID: 34235404; PMCID: PMC8232068.
  • Sprute R, Salmanton-García J, Sal E, Malaj X, Ráčil Z, Ruiz de Alegría Puig C, Falces-Romero I, Barać A, Desoubeaux G, Kindo AJ, Morris AJ, Pelletier R, Steinmann J, Thompson GR, Cornely OA, Seidel D, Stemler J; FungiScope® ECMM/ISHAM Working Group. Invasive infections with Purpureocillium lilacinum: clinical characteristics and outcome of 101 cases from FungiScope® and the literature. J Antimicrob Chemother.2021 May 12;76(6):1593-1603. doi: 10.1093/jac/dkab039. PMID: 33599275; PMCID: PMC8120338. 
  • Stern A, Alonso CD, Garcia-Vidal C, Cardozo C, Slavin M, Yong MK, Ho SA, Mehta Steinke S, Avery RK, Koehler P, Scheid C, Cornely OA, Maertens J, Abi Aad Y, Epstein DJ, Papanicolaou GA, Neofytos D. Safety and efficacy of intravenously administered cidofovir in adult haematopoietic cell transplant recipients: a retrospective multicentre cohort study. J Antimicrob Chemother. 2021 Jul 29:dkab259. doi: 10.1093/jac/dkab259. Epub ahead of print. PMID: 34324678. 
  • Sprute R, Schumacher S, Pauls M, Pauls W, Cornely OA (2021). Delayed Cutaneous Hypersensitivity Reaction to Vaxzevria (ChAdOx1-S) Vaccine against SARS-CoV-2. Drugs R D. 2021 Aug 5:1–4. doi: 10.1007/s40268-021-00358-z. Epub ahead of print. PMID: 34351606; PMCID: PMC8339386. 
  • Jeck J, Jakobs F, Kron A, Franz J, Cornely OA, Kron F (2021). A cost of illness study of COVID-19 patients and retrospective modelling of potential cost savings when administering remdesivir during the pandemic "first wave" in a German tertiary care hospital. Infection. 2021 Aug 18:1–11. doi: 10.1007/s15010-021-01685-8. Epub ahead of print. PMID: 34406606; PMCID: PMC8371942. 
  • Jakob CEM, Classen AY, Stecher M, Engert A, Freund M, Hamprecht A, Jazmati N, Wisplinghoff H, Hallek M, Cornely OA, Vehreschild JJ (2021). Association between the dietary regimen and infection-related complications in neutropenic high-risk patients with cancer. Eur J Cancer. 2021 Aug 13;155:281-290. doi: 10.1016/j.ejca.2021.06.054. Epub ahead of print. PMID: 34399112. 
  • Rudramurthy SM, Hoenigl M, Meis JF, Cornely OA, Muthu V, Gangneux JP, Perfect J, Chakrabarti A; ECMM and ISHAM (2021). ECMM/ISHAM recommendations for clinical management of COVID-19 associated mucormycosis in low- and middle-income countries. Mycoses. 2021 Sep;64(9):1028-1037. doi: 10.1111/myc.13335. Epub 2021 Jul 26. PMID: 34133816. 
  • Theobald SJ, Simonis A, Georgomanolis T, Kreer C, Zehner M, Eisfeld HS, Albert MC, Chhen J, Motameny S, Erger F, Fischer J, Malin JJ, Gräb J, Winter S, Pouikli A, David F, Böll B, Koehler P, Vanshylla K, Gruell H, Suárez I, Hallek M, Fätkenheuer G, Jung N, Cornely OA, Lehmann C, Tessarz P, Altmüller J, Nürnberg P, Kashkar H, Klein F, Koch M, Rybniker J (2021). Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19. EMBO Mol Med. 2021 Aug 9;13(8):e14150. doi: 10.15252/emmm.202114150. Epub 2021 Jun 16. PMID: 34133077; PMCID: PMC8350892. 
  • Hoenigl M, Salmanton-García J, Walsh TJ, Nucci M, Neoh CF, Jenks JD, Lackner M, Sprute R, Al-Hatmi AMS, Bassetti M, Carlesse F, Freiberger T, Koehler P, Lehrnbecher T, Kumar A, Prattes J, Richardson M, Revankar S, Slavin MA, Stemler J, Spiess B, Taj-Aldeen SJ, Warris A, Woo PCY, Young JH, Albus K, Arenz D, Arsic-Arsenijevic V, Bouchara JP, Chinniah TR, Chowdhary A, de Hoog GS, Dimopoulos G, Duarte RF, Hamal P, Meis JF, Mfinanga S, Queiroz-Telles F, Patterson TF, Rahav G, Rogers TR, Rotstein C, Wahyuningsih R, Seidel D, Cornely OA (2021). Global guideline for the diagnosis and management of rare mould infections: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology and the American Society for Microbiology. Lancet Infect Dis. 2021 Aug;21(8):e246-e257. doi: 10.1016/S1473-3099(20)30784-2. Epub 2021 Feb 16. Erratum in: Lancet Infect Dis. 2021 Apr;21(4):e81. PMID: 33606997. 
  • Joachim A, Dewald F, Suárez I, Zemlin M, Lang I, Stutz R, Marthaler A, Bosse HM, Lübke N, Münch J, Bernard MA, Jeltsch K, Tönshoff B, Weidner N, Kräusslich HG, Birzele L, Hübner J, Schmied P, Meyer-Bühn M, Horemheb-Rubio G, Cornely OA, Haverkamp H, Wiesmüller G, Fätkenheuer G, Hero B, Kaiser R, Dötsch J, Rybniker J; B-FAST study group (2021). Pooled RT-qPCR testing for SARS-CoV-2 surveillance in schools - a cluster randomised trial. EClinicalMedicine. 2021 Sep; 39:101082. doi: 10.1016/j.eclinm.2021.101082. Epub 2021 Aug 25. PMID: 34458708 
  • Prattes J, Wauters J, Giacobbe DR, Salmanton-García J, Maertens J, Bourgeois M, Reynders M, Rutsaert L, Van Regenmortel N, Lormans P, Feys S, Reisinger AC, Cornely OA, Lahmer T, Valerio M, Delhaes L, Jabeen K, Steinmann J, Chamula M, Bassetti M, Hatzl S, Rautemaa-Richardson R, Koehler P, Lagrou K, Hoenigl M; ECMM-CAPA Study Group*(2021). Risk factors and outcome of pulmonary aspergillosis in critically ill coronavirus disease 2019 patients- a multinational observational study by the European Confederation of Medical Mycology. Clin Microbiol Infect. 2021 Aug 25: S1198-743X (21)00474-2. doi: 10.1016/j.cmi.2021.08.014. Online ahead of print. PMID: 34454093
  • Wingen-Heimann SM, Cornely OA, J G T Vehreschild M, Wisplinghoff H, Franke B, Schons M, von Bergwelt-Baildon M, Scheid C, Vehreschild JJ (2021). Clinical and pharmacoeconomic evaluation of antifungal prophylaxis with continuous micafungin in patients undergoing allogeneic stem cell transplantation: A six-year cohort analysis. Mycoses. 2021 Apr;64(4):437-444. doi: 10.1111/myc.13232. Epub 2021 Jan 6. PMID: 33354800
  • Zhang J, Zhang Y, Wu D, Cao G, Hamed K, Desai A, Aram JA, Guo X, Fayyad R, Cornely OA (2021). Clinical experience with isavuconazole in healthy volunteers and patients with invasive aspergillosis in China, and the results from an exposure-response analysis. Mycoses. 2021 Apr;64(4):445-456. doi: 10.1111/myc.13233. Epub 2021 Jan 31.PMID: 33355949 
  • Prattes J, Koehler P, Hoenigl M; ECMM-CAPA Study Group (2021). COVID-19 associated pulmonary aspergillosis: regional variation in incidence and diagnostic challenges. Intensive Care Med. 2021 Sep 1:1-2. doi: 10.1007/s00134-021-06510-2. Online ahead of print. PMID: 34468820
  • Jakobs F, Wingen-Heimann SM, Jeck J, Kron A, Cornely OA, Kron F (2021). A budget impact analysis of bezlotoxumab versus standard of care antibiotics only in patients at high risk of CDI recurrence from a hospital management perspective in Germany. BMC Health Serv Res. 2021 Sep 9;21(1):939. doi: 10.1186/s12913-021-06970-8. PMID: 34496836
  • Slavin MA, Chen YC, Cordonnier C, Cornely OA, Cuenca-Estrella M, Donnelly JP, Groll AH, Lortholary O, Marty FM, Nucci M, Rex JH, Rijnders BJA, Thompson GR, Verweij PE, White PL, Hargreaves R, Harvey E, Maertens JA (2021). When to change treatment of acute invasive aspergillosis: an expert viewpoint. J Antimicrob Chemother. 2021 Sep 11: dkab317. doi: 10.1093/jac/dkab317. Online ahead of print. PMID: 34508633
  • Stemler J, Lackner M, Chen SC, Hoenigl M, Cornely OA (2021). EQUAL Score Scedosporiosis/Lomentosporiosis 2021: a European Confederation of Medical Mycology (ECMM) tool to quantify guideline adherence. J Antimicrob Chemother. 2021 Sep 20: dkab355. doi: 10.1093/jac/dkab355. Online ahead of print. PMID: 34542613
  • Steenwyk JL, Mead ME, de Castro PA, Valero C, Damasio A, Dos Santos RAC, Labella AL, Li Y, Knowles SL, Raja HA, Oberlies NH, Zhou X, Cornely OA, Fuchs F, Koehler P, Goldman GH, Rokas A (2021). Genomic and Phenotypic Analysis of COVID-19-Associated Pulmonary Aspergillosis Isolates of Aspergillus fumigatus. Microbiol Spectr. 2021 Sep 3;9(1):e0001021. doi: 10.1128/Spectrum.00010-21. Epub 2021 Jun 9. PMID: 34106569
  • Hoenigl M, Sprute R, Egger M, Arastehfar A, Cornely OA, Krause R, Lass-Flörl C, Prattes J, Spec A, Thompson GR 3rd, Wiederhold N, Jenks JD (2021). The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin. Drugs. 2021 Oct 9:1-27. doi: 10.1007/s40265-021-01611-0. Online ahead of print. PMID: 34626339 
  • Giacobbe DR, Magnasco L, Sepulcri C, Mikulska M, Koehler P, Cornely OA, Bassetti M (2021). Recent advances and future perspectives in the pharmacological treatment of Candida auris infections. Expert Rev Clin Pharmacol. 2021 Oct;14(10):1205-1220. doi:10.1080/17512433.2021.1949285. Epub 2021 Jul 15. PMID: 34176393
  • Seidel D, Simon M, Sprute R, Lubnow M, Evert K, Speer C, Seeßle J, Khatamzas E, Merle U, Behrens C, Wolfgang Blau I, Enghard P, Haas CS, Steinmann J, Kurzai O, Cornely OA (2021). Results from a national survey on COVID-19 associated mucormycosis in Germany: 13 patients from six tertiary hospitals. Mycoses.2021 Oct 16. doi: 10.1111/myc.13379. Online ahead of print. PMID: 34655486
  • Stemler J, Kramer T, Dimitriou V, Wieland U, Schumacher S, Sprute R, Oberste M, Wiesmüller G, Rau H, Pieper S, Bethe U, Lehmann C, Hellmich M, Klein F, Langebartels G, Cornely OA (2021). Mobile PCR-based surveillance for SARS-CoV-2 to reduce visiting restrictions in nursing homes during the COVID-19 pandemic: a pilot study. Infection. 2021 Oct 20:1-10. doi: 10.1007/s15010-021-01716-4. Online ahead of print. PMID: 34669164 
  • Pagano L, Salmanton-García J, Marchesi F, Busca A, Corradini P, Hoenigl M, Klimko N, Koehler P, Pagliuca A, Passamonti F, Verga L, Víšek B, Ilhan O, Nadali G, Weinbergerová B, Córdoba-Mascuñano R, Marchetti M, Collins GP, Farina F, Cattaneo C, Cabirta A, Gomes-Silva M, Itri F, van Doesum J, Ledoux MP, Čerňan M, Jakšić O, Duarte RF, Magliano G, Omrani AS, Fracchiolla NS, Kulasekararaj A, Valković T, Poulsen CB, Machado M, Glenthøj A, Stoma I, Ráčil Z, Piukovics K, Navrátil M, Emarah Z, Sili U, Maertens J, Blennow O, Bergantim R, García-Vidal C, Prezioso L, Guidetti A, Del Principe MI, Popova M, de Jonge N, Ormazabal-Vélez I, Fernández N, Falces-Romero I, Cuccaro A, Meers S, Buquicchio C, Antić D, Al-Khabori M, García-Sanz R, Biernat MM, Tisi MC, Sal E, Rahimli L, Čolović N, Schönlein M, Calbacho M, Tascini C, Miranda-Castillo C, Khanna N, Méndez GA, Petzer V, Novák J, Besson C, Duléry R, Lamure S, Nucci M, Zambrotta G, Žák P, Seval GC, Bonuomo V, Mayer J, López-García A, Sacchi MV, Booth S, Ciceri F, Oberti M, Salvini M, Izuzquiza M, Nunes-Rodrigues R, Ammatuna E, Obr A, Herbrecht R, Núñez-Martín-Buitrago L, Mancini V, Shwaylia H, Sciumè M, Essame J, Nygaard M, Batinić J, Gonzaga Y, Regalado-Artamendi I, Karlsson LK, Shapetska M, Hanakova M, El-Ashwah S, Borbényi Z, Çolak GM, Nordlander A, Dragonetti G, Maraglino AME, Rinaldi A, De Ramón-Sánchez C, Cornely OA; EPICOVIDEHA working group (2021). COVID-19 infection in adult patients with hematological malignancies: a European Hematology Association Survey (EPICOVIDEHA). J Hematol Oncol. 2021 Oct 14;14(1):168. doi: 10.1186/s13045-021-01177-0. PMID: 34649563
  • Podda M, Kovacs M, Hellmich M, Roth R, Zarrouk M, Kraus D, Prinz-Langenohl R, Cornely OA (2021). A randomised controlled multicentre investigator-blinded clinical trial comparing efficacy and safety of surgery versus complex physical decongestive therapy for lipedema (LIPLEG).Trials. 2021 Oct 30;22(1):758. doi: 10.1186/s13063-021-05727-2. PMID: 34717741 
  • Koehler FC, Blomberg L, Brehm TT, Büttner S, Cornely OA, Degen O, Di Cristanziano V, Dolff S, Eberwein L, Hoxha E, Hoyer-Allo KJR, Rudolf S, Späth MR, Wanken M, Müller RU, Burst V (2021). Development and design of the Hantavirus registry - HantaReg - for epidemiological studies, outbreaks and clinical studies on hantavirus disease. Clin Kidney J. 2021 Mar 5;14(11):2365-2370. doi: 10.1093/ckj/sfab053. eCollection 2021 Nov. PMID: 34754431 
  • Busca A, Salmanton-García J, Corradini P, Marchesi F, Cabirta A, Di Blasi R, Dulery R, Lamure S, Farina F, Weinbergerová B, Batinić J, Nordlander A, Lopez-Garcia A, Drgona L, Espigado I, Falces-Romero I, Garcia-Sanz R, Garcia-Vidal C, Guidetti A, Khanna N, Kulesekararaj A, Maertens J, Hoenigl M, Klimko N, Koehler P, Pagliuca A, Passamonti F, Cornely O, Pagano L. COVID-19 and CAR-T cells: current challenges and future directions-a report from the EPICOVIDEHA survey by EHA-IDWP. Blood Adv. 2021 Nov 8:bloodadvances.2021005616. doi: 10.1182/bloodadvances.2021005616. Online ahead of print. PMID: 34749396 
  • Pagano L, Salmanton-García J, Marchesi F, Lopez-Garcia A, Lamure S, Itri F, Gomes da Silva M, Dragonetti G, Falces-Romero I, van Doesum J, Sili U, Labrador J, Calbacho M, Bilgin Y, Weinbergerová B, Serrano Gomez LM, Ribera JM, Malak S, Loureiro-Amigo J, Glenthøj A, Cordoba R, Nunes Rodrigues R, Gonzalez-Lopez TJ, Karlsson LK, Jimenez MJ, Hernández-Rivas JÁ, Jaksic O, Racil Z, Busca A, Corradini P, Hoenigl M, Klimko N, Koehler P, Pagliuca A, Passamonti F, Cornely O (2021). COVID-19 in vaccinated adult patients with hematological malignancies. Preliminary results from EPICOVIDEHA. Blood. 2021 Nov 8:blood.2021014124. doi: 10.1182/blood.2021014124. Online ahead of print. PMID: 34748627 
  • Jeck J, Jakobs F, Kron A, Cornely OA, Kron F (2021). Retrospective modelling of hospital bed capacities associated with the administration of remdesivir during the first wave of COVID-19 in a German metropolitan city. J Antimicrob Chemother. 2021 Nov 25:dkab432. doi: 10.1093/jac/dkab432. Online ahead of print. PMID: 34849943
  • Blankenheim Y, Salmanton-García J, Seifert H, Cornely OA, Koehler P(2021). Attributable mortality of candidemia at a German tertiary hospital from 1997 to 2001 before the introduction of echinocandins.Mycoses. 2021 Nov 30. doi: 10.1111/myc.13406. Online ahead of print. PMID: 34847247
  • Cornely OA, Gow N, Hoenigl M, Warris A (2021). 10th Trends in Medical Mycology Held on 8 to 11 October 2021, Aberdeen, Scotland, Organized by the European Confederation of Medical Mycology (ECMM). J Fungi (Basel). 2021 Oct 28;7(11):916. doi: 10.3390/jof7110916. PMID: 34829205
  • Brockhoff RA, Hicks SR, Salmanton-García J, Dušek D, Stahl JP, Beeching NJ, Cornely OA(2021). Training in infectious diseases across Europe in 2021 - a survey on training delivery, content and assessment. Clin Microbiol Infect. 2021 Nov;27(11):1693.e1-1693.e8. doi: 10.1016/j.cmi.2021.07.033. Epub 2021 Aug 8. PMID: 34371206.
  • Mellinghoff SC, Thelen M, Bruns C, Garcia-Marquez M, Hartmann P, Lammertz T, Lehmann J, Nowag A, Stemler J, Wennhold K, Cornely OA, von Bergwelt-Baildon MS, Schlößer HA(2021). T-cells of invasive candidiasis patients show patterns of T-cell-exhaustion suggesting checkpoint blockade as treatment option. J Infect. 2021 Dec 15:S0163-4453(21)00606-X. doi: 10.1016/j.jinf.2021.12.009. Epub ahead of print. PMID: 34921845.
  • Sprute R, Cornely OA, Chen SC, Seidel D, Schuetz AN, Zhang SX(2021). All You Need To Know and More about the Diagnosis and Management of Rare Yeast Infections. mBio. 2021 Aug 31;12(4):e0159421. doi: 10.1128/mBio.01594-21. Epub 2021 Aug 24. PMID: 34425700; PMCID: PMC8406212.
  •  

Mauro Corrado

  • Fabri M, Villa M, Stanczak MA, Edwards-Hicks J, Corrado M, Pearce EL (2021). Research Techniques Made Simple: Profiling Cellular Energy Metabolism. J Invest Dermatol. 2021 Dec;141(12):2767-2774.e2. doi: 10.1016/j.jid.2021.09.004. PMID: 3480254
  • Puleston DJ, Baixauli F, Sanin DE, Edwards-Hicks J, Villa M, Kabat AM, Kamiński MM, Stanckzak M, Weiss HJ, Grzes KM, Piletic K, Field CS, Corrado M, Haessler F, Wang C, Musa Y, Schimmelpfennig L, Flachsmann L, Mittler G, Yosef N, Kuchroo VK, Buescher JM, Balabanov S, Pearce EJ, Green DR, Pearce EL (2021). Polyamine metabolism is a central determinant of helper T cell lineage fidelity. Cell. 2021 Aug 5;184(16):4186-4202.e20. doi: 10.1016/j.cell.2021.06.007. Epub 2021 Jul 2. PMID: 34216540; PMCID: PMC8358979.
  • O'Sullivan D, Stanczak MA, Villa M, Uhl FM, Corrado M, Klein Geltink RI, Sanin DE, Apostolova P, Rana N, Edwards-Hicks J, Grzes KM, Kabat AM, Kyle RL, Fabri M, Curtis JD, Buck MD, Patterson AE, Regina A, Field CS, Baixauli F, Puleston DJ, Pearce EJ, Zeiser R, Pearce EL(2021).  Fever supports CD8+ effector T cell responses by promoting mitochondrial translation. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2023752118. doi: 10.1073/pnas.2023752118. Epub 2021 Jun 14. PMID: 34161266; PMCID: PMC8237659.
  • Quintana-Cabrera R, Manjarrés-Raza I, Vicente-Gutiérrez C, Corrado M, Bolaños JP, Scorrano L(2021). Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria. Redox Biol. 2021 May;41:101944. doi: 10.1016/j.redox.2021.101944. Epub 2021 Mar 19. PMID: 33780775; PMCID: PMC8039725.
  • Corrado M, Samardžić D, Giacomello M, Rana N, Pearce EL, Scorrano L(2021). Deletion of the mitochondria-shaping protein Opa1 during early thymocyte maturation impacts mature memory T cell metabolism. Cell Death Differ. 2021 Jul;28(7):2194-2206. doi: 10.1038/s41418-021-00747-6. Epub 2021 Mar 1. PMID: 33649469; PMCID: PMC8257785.
  • Fabri M, Villa M, Stanczak MA, Edwards-Hicks J, Corrado M, Pearce EL(2021). Research Techniques Made Simple: Profiling Cellular Energy Metabolism. J Invest Dermatol. 2021 Dec;141(12):2767-2774.e2. doi: 10.1016/j.jid.2021.09.004. PMID: 34802549.

Joris Deelen

  • Deelen J (2021). Targeting multimorbidity: Using healthspan and lifespan to identify biomarkers of ageing that pinpoint shared disease mechanisms. EBioMedicine. 2021 May;67:103364. doi: 10.1016/j.ebiom.2021.103364. Epub 2021 May 6. PMID: 33965870; PMCID: PMC8114127.

 

Constantinos Demetriades

  • Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G, Genomics England Research Consortium, de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K (2021). G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling. Cell. 2021 Jan 18:S0092-8674(20)31694-9. doi: 10.1016/j.cell.2020.12.024. Online ahead of print. PMID: 33497611
  • Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D. TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. Mol Cell. 2021 Apr 30:S1097-2765(21)00324-5. doi: 10.1016/j.molcel.2021.04.019. Epub ahead of print. PMID: 33974911. 
  • Nüchel J, Tauber M, Nolte JL, Mörgelin M, Türk C, Eckes B, Demetriades C, Plomann M (2021). An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress. Mol Cell.2021 Jul 5:S1097-2765(21)00497-4. doi: 10.1016/j.molcel.2021.06.017. Epub ahead of print. PMID: 34245671.
  • Demetriades C,Nuüchel J, Plomann M (2021). GRASPing the unconventional secretory machinery to bridge cellular stress signaling to the extracellular proteome. Cell Stress. 2021 Oct 15;5(11):173-175. doi: 10.15698/cst2021.11.259. eCollection 2021 Nov. PMID: 34782889 
  • Fernandes AS, Demetriades C (2021). The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging. Front. Aging. 2021 August 27. doi:10.3389/fragi.2021.707372
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Martin Denzel

  • Schiffer I, Gerisch B, Kawamura K, Laboy R, Hewitt J, Denzel MS, Mori MA, Vanapalli S, Shen Y, Symmons O, Antebi A (2021). miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging. Elife. 2021 Jul 27;10:e66768. doi: 10.7554/eLife.66768. PMID: 34311841; PMCID: PMC8315803.
  • Allmeroth K, Horn M, Kroef V, Miethe S, Müller RU, Denzel MS (2021). Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma. Leukemia.2021 Mar;35(3):887-892. doi: 10.1038/s41375-020-0989-4. Epub 2020 Jul 20. PMID: 32690882 
  • Allmeroth K, Kim CS, Annibal A, Pouikli A, Koester J, Derisbourg MJ, Andrés Chacón-Martínez C, Latza C, Antebi A,Tessarz P, Wickström SA, Denzel MS. N1-acetylspermidine is a determinant of hair follicle stem cell fate. J Cell Sci. 2021 May 1;134(9):jcs252767. doi: 10.1242/jcs.252767. Epub 2021 May 11. PMID: 33973637.
  • Derisbourg MJ, Wester LE, Baddi R, Denzel MS. Mutagenesis screen uncovers lifespan extension through integrated stress response inhibition without reduced mRNA translation. Nat Commun. 2021 Mar 15;12(1):1678. doi: 10.1038/s41467-021-21743-x. PMID: 33723245; PMCID: PMC7960713.
  • Ruegenberg S, Mayr FAMC, Atanassov I, Baumann U, Denzel MS. Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun. 2021 Apr 12;12(1):2176. doi: 10.1038/s41467-021-22320-y. PMID: 33846315.
  • Allmeroth K, Denzel MS (2021). The RATIOnal Role of Polyamines in Epidermal Differentiation. J Invest Dermatol. 2021 Sep;141(9):2105-2107. doi: 10.1016/j.jid.2021.02.011. PMID: 34420674
  • Guerrero GA, Derisbourg MJ, Mayr FA, Wester LE, Giorda M, Dinort JE, Hartman MD, Schilling K, Alonso-De Gennaro MJ, Lu RJ, Benayoun BA, Denzel MS (2021). NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants. Elife. 2021 Aug 27;10:e53174. doi: 10.7554/eLife.53174. PMID: 34448454
  • Derisbourg, M.J., Hartman, M.D. & Denzel, M.S(2021). Modulating the integrated stress response to slow aging and ameliorate age-related pathology. Nat Aging 1, 760–768 (2021). doi.org/10.1038/s43587-021-00112-9

Dominik Pesta

  • Strasser B, Pesta D, Rittweger J, Burtscher J, Burtscher M (2021). Nutrition for Older Athletes: Focus on Sex-Differences. Nutrients. 2021 Apr 22;13(5):1409. doi: 10.3390/nu13051409. PMID: 33922108; PMCID: PMC8143537.
  • Gratl A, Wipper S, Frese JP, Raude B, Greiner A, Pesta D. (2021). The Role of Mitochondrial Function in Peripheral Arterial Disease: Insights from Translational Studies. Int J Mol Sci. 2021 Aug 6;22(16):8478. doi: 10.3390/ijms22168478. PMID: 34445191
  • Hoppel F, Garcia-Souza LF, Kantner-Rumplmair W, Burtscher M, Gnaiger E, Pesta D,Calabria E (2021). Human Platelet Mitochondrial Function Reflects Systemic Mitochondrial Alterations: A Protocol for Application in Field Studies. Cells. 2021 Aug 14;10(8):2088. doi: 10.3390/cells10082088. PMID: 34440857

Sabine Eming

  • Ding X, Kakanj P, Leptin M, Eming SA (2021).. Regulation of the wound healing response during aging. J Invest Dermatol. 2021 Feb 5;S0022-202X(20)32360-5. doi: 10.1016/j.jid.2020.11.014. Online ahead of print 
  • Hadrian K, Willenborg S, Bock F, Cursiefen C, Eming SA, Hos D. Macrophage-Mediated Tissue Vascularization: Similarities and Differences Between Cornea and Skin. Front Immunol. 2021 Apr 7;12:667830. doi: 10.3389/fimmu.2021.667830. PMID: 33897716; PMCID: PMC8058454. 
  • Eming SA, Murray PJ, Pearce EJ (2021). Metabolic orchestration of the wound healing response. Cell Metab. 2021 Aug 9:S1550-4131(21)00362-4. doi: 10.1016/j.cmet.2021.07.017. Epub ahead of print. PMID: 34384520.
  • Willenborg S, Sanin DE, Jais A, Ding X, Ulas T, Nüchel J, Popović M, MacVicar T, Langer T, Schultze JL, Gerbaulet A, Roers A, Pearce EJ, Brüning JC, Trifunovic A, Eming SA (2021). Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab. 2021 Oct 25:S1550-4131(21)00482-4. doi: 10.1016/j.cmet.2021.10.004. Online ahead of print. PMID: 34715039

Mafalda Escobar-Henriques 

  • Buntenbroich, I., Simões, T. Escobar-Henriques, M (2021). Analysis of Protein Stability by Synthesis Shutoff. Bio-protocol. 2021 Nov 20;11(22):e4225. doi:10.21769/BioProtoc.4225. PMID: 34909446

Lukas P. Frenzel

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798 
  • Neuendorff NR, Frenzel LP, Leuschner F, Fremd C (2021). Integrating clonal haematopoiesis into geriatric oncology: The ARCH between aging, cardiovascular disease and malignancy. J Geriatr Oncol. 2021 Apr;12(3):479-482. doi: 10.1016/j.jgo.2020.09.006. Epub 2020 Sep 23. PMID: 32978103.
  • Flores-Romero H, Hohorst L, John M, Albert MC, King LE, Beckmann L, Szabo T, Hertlein V, Luo X, Villunger A, Frenzel LP, Kashkar H, Garcia-Saez AJ(2021). BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. EMBO J. 2021 Dec 21:e108690. doi: 10.15252/embj.2021108690. Epub ahead of print. PMID: 34931711. 
  • Beckmann L, Berg V, Dickhut C, Sun C, Merkel O, Bloehdorn J, Robrecht S, Seifert M, da Palma Guerreiro A, Claasen J, Loroch S, Oliverio M, Underbayev C, Vaughn L, Thomalla D, Hülsemann MF, Tausch E, Fischer K, Fink AM, Eichhorst B, Sickmann A, Wendtner CM, Stilgenbauer S, Hallek M, Wiestner A, Zahedi RP, Frenzel LP (2021). MARCKS affects cell motility and response to BTK inhibitors in CLL. Blood. 2021 Aug 19;138(7):544-556. doi: 10.1182/blood.2020009165. PMID: 33735912; PMCID: PMC8377477. 
  • Frenzel LP (2021). PI3K/BCL2: illusion or promise for RS? Blood. 2021 Jun 17;137(24):3319-3321. doi: 10.1182/blood.2021011854. PMID: 34137851.

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Henning Fenselau

  • Bozadjieva-Kramer N, Ross RA, Johnson DQ, Fenselau H, Haggerty DL, Atwood B, Lowell B, Flak JN (2021). The Role of Mediobasal Hypothalamic PACAP in the Control of Body Weight and Metabolism. Endocrinology. 2021 Jan 18:bqab012. doi: 10.1210/endocr/bqab012. Online ahead of print. PMID: 33460433.
  • Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC (2021). Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat Neurosci. 2021 May 17. doi: 10.1038/s41593-021-00854-0. Epub ahead of print. PMID: 34002087.
  • Borgmann D, Ciglieri E, Biglari N, Brandt C, Cremer AL, Backes H, Tittgemeyer M, Wunderlich FT, Brüning JC, Fenselau H (2021). Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metab. 2021 May 21:S1550-4131(21)00219-9. doi: 10.1016/j.cmet.2021.05.002. Epub ahead of print. PMID: 34043943.
  • Borgmann D, Rigoux L, Kuzmanovic B, Edwin Thanarajah S, Münte TF, Fenselau H, Tittgemeyer M (2021). Technical Note: Modulation of fMRI brainstem responses by transcutaneous vagus nerve stimulation. Neuroimage. 2021 Sep 10; 244:118566. doi: 10.1016/j.neuroimage.2021.118566. Online ahead of print. PMID: 34509623

 

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Ana J. Garcia-Saez

  • Dadsena S, Jenner A, García-Sáez AJ (2021). Mitochondrial outer membrane permeabilization at the single molecule level. Cell Mol Life Sci. 2021 Feb 12. doi: 10.1007/s00018-021-03771-4. Online ahead of print. PMID: 33576840 Review
  • Ros U, Pedrera L, Garcia-Saez AJ (2021). Techniques for studying membrane pores. Curr Opin Struct Biol. 2021 May 1;69:108-116. doi: 10.1016/j.sbi.2021.03.012. Epub ahead of print. PMID: 33945958
  • Danial JSH, Shalaby R, Cosentino K, Mahmoud MM, Medhat F, Klenerman D, Garcia Saez AJ (2021). DeepSinse: deep learning based detection of single molecules. Bioinformatics. 2021 May 8:btab352. doi: 10.1093/bioinformatics/btab352. Online ahead of print. PMID: 33964131 
  • Peña-Blanco A, Haschka MD, Jenner A, Zuleger T, Proikas-Cezanne T,Villunger A, García-Sáez AJ (2021). Correction: Drp1 modulates mitochondrial stress responses to mitotic arrest. Cell Death Differ. 2021 Jul 23. doi: 10.1038/s41418-021-00831-x. Epub ahead of print. Erratum for: Cell Death Differ. 2020 Sep;27(9):2620-2634. PMID: 34302122. 
  • Dadsena S, King LE, García-Sáez AJ (2021). Apoptosis regulation at the mitochondria membrane level. Biochim Biophys Acta Biomembr. 2021 Jul 31:183716. doi: 10.1016/j.bbamem.2021.183716. Epub ahead of print. PMID: 34343535.
  • Flores-Romero H, Hohorst L, John M, Albert MC, King LE, Beckmann L, Szabo T, Hertlein V, Luo X, Villunger A, Frenzel LP, Kashkar H, Garcia-Saez AJ(2021). BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. EMBO J. 2021 Dec 21:e108690. doi: 10.15252/embj.2021108690. Epub ahead of print. PMID: 34931711.
  • Cosentino K, Hermann E, von Kügelgen N, Unsay JD, Ros U, García-Sáez AJ (2021). Force Mapping Study of Actinoporin Effect in Membranes Presenting Phase Domains. Toxins (Basel). 2021 Sep 18;13(9):669. doi: 10.3390/toxins13090669. PMID: 34564674; PMCID: PMC8473010.
  • Murad F, Garcia-Saez AJ (2021). Bcl-xL inhibits tBid and Bax via distinct mechanisms. Faraday Discuss.2021 Dec 24;232(0):86-102. doi: 10.1039/d0fd00045k. PMID: 34528939.

Michael Hallek

  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798
  • Pan H, Renaud L, Chaligne R, Bloehdorn J, Tausch E, Mertens D, Fink AM, Fischer K, Zhang C, Betel D, Gnirke A, Imielinski M, Moreaux J, Hallek M, Meissner A, Stilgenbauer S, Wu CJ, Elemento O, Landau DA. Discovery of candidate DNA methylation cancer driver genes. Cancer Discov. 2021 May 10:candisc.1334.2020. doi: 10.1158/2159-8290.CD-20-1334. Epub ahead of print. PMID: 33972312. 
  • Augustin M, Schommers P, Stecher M, Dewald F, Gieselmann L, Gruell H, Horn C, Vanshylla K, Cristanziano VD, Osebold L, Roventa M, Riaz T, Tschernoster N, Altmueller J, Rose L, Salomon S, Priesner V, Luers JC, Albus C, Rosenkranz S, Gathof B, Fätkenheuer G, Hallek M, Klein F, Suárez I, Lehmann C (2021). Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study. Lancet Reg Health Eur. 2021 Jul;6:100122. doi: 10.1016/j.lanepe.2021.100122. Epub 2021 May 18. PMID: 34027514; PMCID: PMC8129613. 
  • Lobastova L, Lettau M, Babatz F, de Oliveira TD, Nguyen PH, Pauletti BA, Schauss AC, Dürkop H, Janssen O, Paes Leme AF, Hallek M, Hansen HP (2021). CD30-Positive Extracellular Vesicles Enable the Targeting of CD30-Negative DLBCL Cells by the CD30 Antibody-Drug Conjugate Brentuximab Vedotin. Front Cell Dev Biol. 2021 Jul 30;9:698503. doi: 10.3389/fcell.2021.698503. PMID: 34395429; PMCID: PMC8362802.
  • Jakob CEM, Classen AY, Stecher M, Engert A, Freund M, Hamprecht A, Jazmati N, Wisplinghoff H, Hallek M, Cornely OA, Vehreschild JJ (2021). Association between the dietary regimen and infection-related complications in neutropenic high-risk patients with cancer. Eur J Cancer. 2021 Aug 13;155:281-290. doi: 10.1016/j.ejca.2021.06.054. Epub ahead of print. PMID: 34399112. 
  • Theobald SJ, Simonis A, Georgomanolis T, Kreer C, Zehner M, Eisfeld HS, Albert MC, Chhen J, Motameny S, Erger F, Fischer J, Malin JJ, Gräb J, Winter S, Pouikli A, David F, Böll B, Koehler P, Vanshylla K, Gruell H, Suárez I, Hallek M, Fätkenheuer G, Jung N, Cornely OA, Lehmann C, Tessarz P, Altmüller J, Nürnberg P, Kashkar H, Klein F, Koch M, Rybniker J (2021). Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19. EMBO Mol Med. 2021 Aug 9;13(8):e14150. doi: 10.15252/emmm.202114150. Epub 2021 Jun 16. PMID: 34133077; PMCID: PMC8350892.
  • Tzaridis T, Bachurski D, Liu S, Surmann K, Babatz F, Gesell Salazar M, Völker U, Hallek M, Herrlinger U, Vorberg I, Coch C, Reiners KS, Hartmann G (2021). Extracellular Vesicle Separation Techniques Impact Results from Human Blood Samples: Considerations for Diagnostic Applications. Int J Mol Sci. 2021 Aug 26;22(17):9211. doi: 10.3390/ijms22179211. PMID: 34502122
  • Fürstenau M, Fink AM, Schilhabel A, Weiss J, Robrecht S, Eckert R, de la Serna J, Crespo M, Coscia M, Vitale C, Böttcher S, Weppner G, Ritgen M, Stilgenbauer S, Tausch E, Fischer K, Hallek M, Eichhorst B, Brüggemann M, Herling CD (2021). B-cell acute lymphoblastic leukemia in patients with chronic lymphocytic leukemia treated with lenalidomide. Blood. 2021 Apr 22;137(16):2267-2271. doi: 10.1182/blood.2020008609. PMID: 33512465. Clinical Trial. No abstract available.
  • Fürstenau M, Giza A, Stumpf T, Robrecht S, Maurer C, Linde H, Jacobasch L, Dörfel S, Aldaoud A, von Tresckow J, Koenigsmann M, Gaska T, Kaiser U, Harich HD, Fischer K, Eichhorst B, Hallek M, Fink AM (2021). Second primary malignancies in treated and untreated patients with chronic lymphocytic leukemia. Am J Hematol. 2021 Sep 30. doi: 10.1002/ajh.26363. Online ahead of print. PMID: 34591989
  • Garcia Borrega J, Heger JM, Koehler P, Holtick U, Hallek M, Scheid C, Böll B, Shimabukuro-Vornhagen A, Kochanek M, Eichenauer DA (2021). Allogeneic stem cell transplant recipients admitted to the intensive care unit during the peri-transplant period have unfavorable outcomes-results of a retrospective analysis from a German university hospital. Ann Hematol. 2021 Oct 20. doi: 10.1007/s00277-021-04698-3. Online ahead of print. PMID: 34668981
  • Beckmann L, Berg V, Dickhut C, Sun C, Merkel O, Bloehdorn J, Robrecht S, Seifert M, da Palma Guerreiro A, Claasen J, Loroch S, Oliverio M, Underbayev C, Vaughn L, Thomalla D, Hülsemann MF, Tausch E, Fischer K, Fink AM, Eichhorst B, Sickmann A, Wendtner CM, Stilgenbauer S, Hallek M, Wiestner A, Zahedi RP, Frenzel LP(2021). MARCKS affects cell motility and response to BTK inhibitors in CLL. Blood. 2021 Aug 19;138(7):544-556. doi: 10.1182/blood.2020009165. PMID: 33735912; PMCID: PMC8377477.

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Marco Herling

  • Böttcher M, Bruns H, Völkl S, Lu J, Chartomatsidou E, Papakonstantinou N, Mentz K, Büttner-Herold M, Zenz T, Herling M, Huber W, Ghia P, Stamatopoulos K, Mackensen A, Mougiakakos D. Control of PD-L1 expression in CLL-cells by stromal triggering of the Notch-c-Myc-EZH2 oncogenic signaling axis. J Immunother Cancer. 2021 Apr;9(4):e001889. doi: 10.1136/jitc-2020-001889. PMID: 33931470. 
  • Wahnschaffe L, Herling M (2021). Hijacking the Pathway: Perspectives in the Treatment of Mature T-cell Leukemias. Hemasphere.2021 Jun 1;5(6):e573. doi: 10.1097/HS9.0000000000000573. PMID: 34095757; PMCID: PMC8171373.
  • Braun T, Dechow A, Friedrich G, Seifert M, Stachelscheid J, Herling M(2021). Advanced Pathogenetic Concepts in T-Cell Prolymphocytic Leukemia and Their Translational Impact. Front Oncol. 2021 Nov 19;11:775363. doi: 10.3389/fonc.2021.775363. PMID: 34869023; PMCID: PMC8639578.

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Jan Hoeijmakers

  • Birkisdóttir MB, Jaarsma D, Brandt RMC, Barnhoorn S, van Vliet N, Imholz S, van Oostrom CT, Nagarajah B, Portilla Fernández E, Roks AJM, Elgersma Y, van Steeg H, Ferreira JA, Pennings JLA, Hoeijmakers JHJ, Vermeij WP, Dollé MET (2021). Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice. Aging Cell. 2021 Jan 23:e13302. doi: 10.1111/acel.13302. Online ahead of print.PMID: 33484480
  • Botta E, Theil AF, Raams A, Caligiuri G, Giachetti S, Bione S, Accadia M, Lombardi A, Smith DEC, Mendes MI, Swagemakers SMA, van der Spek PJ, Salomons GS, Hoeijmakers JHJ, Yesodharan D, Nampoothiri S, Ogi T, Lehmann AR, Orioli D, Vermeulen W. Protein instability associated with AARS1 and MARS1 mutations causes Trichothiodystrophy. Hum Mol Genet. 2021 Apr 28:ddab123. doi: 10.1093/hmg/ddab123. Epub ahead of print. PMID: 33909043. Van't Sant LJ, White JJ, Hoeijmakers JHJ, Vermeij WP, Jaarsma D (2021).
  • In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration. Acta Neuropathol Commun. 2021 May 21;9(1):94. doi: 10.1186/s40478-021-01200-y. PMID: 34020718; PMCID: PMC8139001.

Thorsten Hoppe    

  • Ottens F, Franz A, Hoppe T (2021). Build-UPS and break-downs: metabolism impacts on proteostasis and aging. Cell Death Differ. 2021 Jan 4. doi: 10.1038/s41418-020-00682-y. Online ahead of print. PMID: 33398091 Review 
  • Müller L, Kutzner CE, Balaji V, Hoppe T (2021). In Vitro Analysis of E3 Ubiquitin Ligase Function. J Vis Exp. 2021 May 14;(171). doi: 10.3791/62393. PMID: 34057440.
  • Franz A, Valledor P, Ubieto-Capella P, Pilger D, Galarreta A, Lafarga V, Fernández-Llorente A, de la Vega-Barranco G, den Brave F, Hoppe T, Fernandez-Capetillo O, Lecona E (2021). USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork. Cell Rep. 2021 Oct 12;37(2):109819. doi: 10.1016/j.celrep.2021.109819. PMID: 34644576
  • Finger F, Ottens F, Hoppe T (2021). The Argonaute Proteins ALG-1 and ALG-2 Are Linked to Stress Resistance and Proteostasis. MicroPubl Biol. 2021 Oct 14;2021:10.17912/micropub.biology.000457. doi: 10.17912/micropub.biology.000457. eCollection 2021.PMID: 34723149
  • Höhfeld J., Benzing T., Bloch, W. Fürst D.O., Gehlert S., Hesse M., Hoffmann B., Hoppe T., Huesgen P.F., Köhn M., Kolanus W., Merkel R., NIessen C.M., Pokrzywa W., Rinschen M.M., Wachten D., Warscheid B. (2021). Maintaining proteostasis under mechanical stress. EMBO Rep. 2021 Aug 4;22(8):e52507. doi: 10.15252/embr.202152507.Epub 2021 Jul 26.

Pitter Huesgen

  • Passarge A, Demir F, Green K, Depotter JRL, Scott B, Huesgen PF, Doehlemann G, Misas Villamil JC (2021). Host apoplastic cysteine protease activity is supressed during the mutualistic association of Lolium perenne and Epichloë festucae. J Exp Bot. 2021 Feb 25:erab088. doi: 10.1093/jxb/erab088. Online ahead of print. PMID: 33630999 
  • Mooney BC, Mantz M, Graciet E, Huesgen PF (2021). Cutting the line: manipulation of plant immunity by bacterial type III effector proteases. J Exp Bot. 2021 Feb 26:erab095. doi: 10.1093/jxb/erab095. Online ahead of print. PMID: 33640987
  • Demir F, Kizhakkedathu JN, Rinschen MM, Huesgen PF (2021). MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets. Anal Chem. 2021 Mar 17. doi: 10.1021/acs.analchem.1c00310. Online ahead of print. PMID: 33729755 
  • Hofsetz E., Huesgen P.F.,Trifunovic A.(2021) Identification of Putative Mitochondrial Protease Substrates. In: Minczuk M., Rorbach J.. Mitochondrial Gene Expression. Methods in Molecular Biology, vol 2192. Humana, New York, NY. doi: 10.1007/978-1-0716-0834-0_21. 
  • Demir F, Troldborg A, Thiel S, Lassé M, Huesgen PF, Tomas NM, Wiech T, Rinschen MM. Proteolysis and inflammation of the kidney glomerulus. Cell Tissue Res. 2021 Apr 17:1–12. doi: 10.1007/s00441-021-03433-8. Epub ahead of print. PMID: 33864499; PMCID: PMC8052535. 
  • Drexelius M, Reinhardt A, Grabeck J, Cronenberg T, Nitsche F, Huesgen PF, Maier B, Neundorf I. Multistep optimization of a cell-penetrating peptide towards its antimicrobial activity. Biochem J. 2021 Jan 15;478(1):63-78. doi: 10.1042/BCJ20200698. PMID: 33313751. 
  • Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B (2021). Maintaining proteostasis under mechanical stress. EMBO Rep. 2021 Aug 4;22(8):e52507. doi: 10.15252/embr.202152507. Epub 2021 Jul 26. PMID: 34309183.
  • Dall E, Stanojlovic V, Demir F, Briza P, Dahms SO, Huesgen PF, Cabrele C, Brandstetter H (2021). The Peptide Ligase Activity of Human Legumain Depends on Fold Stabilization and Balanced Substrate Affinities. ACS Catal. 2021 Oct 1;11(19):11885-11896. doi: 10.1021/acscatal.1c02057. Epub 2021 Sep 10. PMID: 34621593
  • Kimura K, Ooms A, Graf-Riesen K, Kuppusamy M, Unger A, Schuld J, Daerr J, Lother A, Geisen C, Hein L, Takahashi S, Li G, Röll W, Bloch W, van der Ven PFM, Linke WA, Wu SM, Huesgen PF, Höhfeld J, Fürst DO, Fleischmann BK, Hesse M (2021): Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy. Nat Commun. 12(1):3575. doi: 10.1038/s41467-021-23858-7
  • Alcaraz LB, Mallavialle A, David T, Derocq D, Delolme F, Dieryckx C, Mollevi C, BoissieÃÄre-Michot F, Simony-Lafontaine J, Du Manoir S, Huesgen PF, Overall CM, Tartare-Deckert S, Jacot W, Chardes T, Guiu S, Roger P, Reinheckel T, Moali C, Liaudet-Coopman E (2021). A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment. Theranostics. 11(13):6173-6192. doi: 10.7150/thno.58254.

Sandra Iden 

  • Li M, Iden S (2021) Emerging Laminin-332‒Dependent and ‒Independent Roles for Integrin α3 in Protumorigenic Signaling. J Invest Dermatol. 2021 Apr;141(4):713-716. doi: 10.1016/j.jid.2020.08.017. PMID: 33752808
  • Dias Gomes M, Iden S (2021). Orchestration of tissue-scale mechanics and fate decisions by polarity signalling. EMBO J. 2021 Jun 15;40(12):e106787. doi: 10.15252/embj.2020106787. Epub 2021 May 17. PMID: 33998017
  • Koehler S, Odenthal J, Ludwig V, Jess DU, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HHH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T,Iden S, Brinkkoetter PT(2021). Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int. 2021 Dec 17:S0085-2538(21)01150-9. doi: 10.1016/j.kint.2021.11.030. Epub ahead of print. PMID: 34929254.

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  • Jachimowicz RD, Pieper L, Reinke S, Gontarewicz A, Plütschow A, Haverkamp H, Frauenfeld L, Fend F, Overkamp M, Jochims F, Thorns C, Leo Hansmann M, Möller P, Rosenwald A, Stein H, Reinhardt HC, Borchmann P, von Tresckow B, Engert A, Klapper W (2021). Whole-slide image analysis of the tumor microenvironment identifies low B-cell content as a predictor of adverse outcome in patients with advanced-stage classical Hodgkin lymphoma treated with BEACOPP. Haematologica. 2021 Jun 1;106(6):1684-1692. doi: 10.3324/haematol.2019.243287. PMID: 32381573; PMCID: PMC8168506.
  • Schmidt J, Goergens J, Pochechueva T, Kotter A, Schwenzer N, Sitte M, Werner G, Altmüller J, Thiele H, Nürnberg P, Isensee J, Li Y, Müller C, Leube B, Reinhardt HC, Hucho T, Salinas G, Helm M, Jachimowicz RD, Wieczorek D, Kohl T, Lehnart SE, Yigit G, Wollnik B (2021). Biallelic variants in YRDC cause a developmental disorder with progeroid features. Hum Genet. 2021 Dec;140(12):1679-1693. doi: 10.1007/s00439-021-02347-3. Epub 2021 Sep 20. PMID: 34545459
  • Jachimowicz RD, Klapper W, Glehr G, Müller H, Haverkamp H, Thorns C, Hansmann ML, Möller P, Stein H, Rehberg T, von Tresckow B, Reinhardt HC, Borchmann P, Chan FC, Spang R, Scott DW, Engert A, Steidl C, Altenbuchinger M, Rosenwald A (2021). Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP. Leukemia. 2021 Dec;35(12):3589-3593. doi: 10.1038/s41375-021-01314-1. Epub 2021 Jun 10. PMID: 34112956
  • Murakami T, Shoji Y, Nishi T, Chang SC, Jachimowicz RD, Hoshimoto S, Ono S, Shiloh Y, Takeuchi H, Kitagawa Y, Hoon DSB, Bustos MA. Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma. Mol Oncol. 2021 Apr;15(4):1069-1087. doi: 10.1002/1878-0261.12929. Epub 2021 Mar 8. PMID: 33605536

Frank Jessen

  • Sannemann L, Müller T, Waterink L, Zwan M, Wimo A, Stomrud E, Pinó S, Arrufat J, Rodríguez-Gomez O, Benaque A, Bon J, Ferreira D, Johansson G, Dron A, Dumas A, Georges J, Kramberger MG, Visser PJ, Winblad B, Campo L, Boada M, Jessen F; MOPEAD consortium (2021). General practitioners' attitude toward early and pre-dementia diagnosis of AD in five European countries-A MOPEAD project survey.  Alzheimers Dement (Amst). 2021 Feb 23;13(1):e12130. doi: 10.1002/dad2.12130. eCollection 2021. PMID: 33665337  
  • Marchant NL, Barnhofer T, Coueron R, Wirth M, Lutz A, Arenaza-Urquijo EM, Collette F, Poisnel G, Demnitz-King H, Schild AK, Coll-Padros N, Delphin-Combe F, Whitfield T, Schlosser M, Gonneaud J, Asselineau J, Walker Z, Krolak-Salmon P, Molinuevo JL, Frison E, Chételat G, Jessen F, Klimecki OM; The Medit-Ageing Research Group. Effects of a Mindfulness-Based Intervention versus Health Self-Management on Subclinical Anxiety in Older Adults with Subjective Cognitive Decline: The SCD-Well Randomized Superiority Trial. Psychother Psychosom. 2021 Apr 19:1-10. doi: 10.1159/000515669. Epub ahead of print. PMID: 33873195. 
  • Hammes J, Bischof GN, Bohn KP, Onur Ö, Schneider A, Fliessbach K, Hönig MC, Jessen F, Neumaier B, Drzezga A, van Eimeren T (2021). One-Stop Shop: 18F-Flortaucipir PET Differentiates Amyloid-Positive and -Negative Forms of Neurodegenerative Diseases. J Nucl Med. 2021 Feb;62(2):240-246. doi: 10.2967/jnumed.120.244061. Epub 2020 Jul 3. PMID: 32620704.
  • Ballarini T, Melo van Lent D, Brunner J, Schröder A, Wolfsgruber S, Altenstein S, Brosseron F, Buerger K, Dechent P, Dobisch L, Duzel E, Ertl-Wagner B, Fliessbach K, Freiesleben SD, Frommann I, Glanz W, Hauser D, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk M, Perneczky R, Peters O, Priller J, Ramirez A, Rauchmann B, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel SJ, Vukovich R, Wiltfang J, Jessen F, Wagner M; DELCODE study group. Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age. Neurology. 2021 May 5:10.1212/WNL.0000000000012067. doi: 10.1212/WNL.0000000000012067. Epub ahead of print. PMID: 33952652.
  • Hansen N, Singh A, Bartels C, Brosseron F, Buerger K, Cetindag AC, Dobisch L, Dechent P, Ertl-Wagner BB, Fliessbach K, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Vukovich R, Wiltfang J, Duezel E, Jessen F, Goya-Maldonado R. Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline. Front Aging Neurosci. 2021 Apr 21;13:626974. doi: 10.3389/fnagi.2021.626974. PMID: 33967736; PMCID: PMC8097178. 
  • Rauchmann BS, Ersoezlue E, Stoecklein S, Keeser D, Brosseron F, Buerger K, Dechent P, Dobisch L, Ertl-Wagner B, Fliessbach K, Haynes JD, Heneka MT, Incesoy EI, Janowitz D, Kilimann I, Laske C, Metzger CD, Munk MH, Peters O, Priller J, Ramirez A, Roeske S, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Vukovich R, Wagner M, Wiltfang J, Yakupov R, Duezel E, Jessen F, Perneczky R; DELCODE study group and the Alzheimer's Disease Neuroimaging Initiative (ADNI) (2021). Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes. Cereb Cortex. 2021 Jun 3:bhab130. doi: 10.1093/cercor/bhab130. Epub ahead of print. PMID: 34080613. 
  • Boada M, Rodrigo A, Jessen F, Wimblad B, Kramberger M, Visser PJ, Simó R, Rodríguez-Gomez O, Ciudin A, Georges J, Dumas A, Maguire P, Krivec D, Wimo A, Valero S, Alegret M, Jamilis L, Zwan M, Sannemann L, Arrufat J, Stomrud E, Johansson G, Shering C, Glaysher B, Stewart N, Belger M, Iradier F, Campo L; MOPEAD consortium (2021). Complementary pre-screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project. Alzheimers Dement. 2021 Jul 26. doi: 10.1002/alz.12441. Epub ahead of print. PMID: 34310061. 
  • Schild AK, Volk J, Scharfenberg D, Schuermann K, Meiberth D, Onur OA, Jessen F, Maier F (2021). Social Cognition in Patients with Amnestic Mild Cognitive Impairment and Mild Dementia of the Alzheimer Type. J Alzheimers Dis. 2021 Aug 13. doi: 10.3233/JAD-201126. Epub ahead of print. PMID: 34397409. 
  • Wimo A, Belger M, Bon J, Jessen F, Dumas A, Kramberger MG, Jamilis L, Johansson G, Rodrigo Salas A, Rodríguez Gómez O, Sannemann L, Stoekenbroek M, Gurruchaga Telleria M, Valero S, Vermunt L, Waterink L, Winblad B, Visser PJ, Zwan M, Boada M; Collaborators and members of the MOPEAD consortium (2021). A Cost-Consequence Analysis of Different Screening Procedures in Alzheimer's Disease: Results from the MOPEAD Project. J Alzheimers Dis. 2021 Aug 16. doi: 10.3233/JAD-210303. Epub ahead of print. PMID: 34420954.
  • Rostamzadeh A, Schwegler C, Gil-Navarro S, Rosende-Roca M, Romotzky V, Ortega G, Canabate P, Moreno M, Schmitz-Luhn B, Boada M, Jessen F, Woopen C (2021). Biomarker-Based Risk Prediction of Alzheimer's Disease Dementia in Mild Cognitive Impairment: Psychosocial, Ethical, and Legal Aspects. J Alzheimers Dis.  2021;80(2):601-617. doi: 10.3233/JAD-200484. PMID: 33554900
  • Frisoni GB, Molinuevo JL, Altomare D, Carrera E, Barkhof F, Berkhof J, Delrieu J, Dubois B, Kivipelto M, Nordberg A, Schott JM, van der Flier WM, Vellas B, Jessen F, Scheltens P, Ritchie C (2021). Precision prevention of Alzheimer's and other dementias: Anticipating future needs in the control of risk factors and implementation of disease-modifying therapies.Alzheimers Dement. 2020 Oct;16(10):1457-1468. doi: 10.1002/alz.12132. Epub 2020 Aug 20. PMID: 32815289
  • Islam MR, Kaurani L, Berulava T, Heilbronner U, Budde M, Centeno TP, Elerdashvili V, Zafieriou MP, Benito E, Sertel SM, Goldberg M, Senner F, Kalman JL, Burkhardt S, Oepen AS, Sakib MS, Kerimolgu C, Wirths O, Bickeböller H, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Heneka MT, Janowitz D, Kilimann I, Kleinedam L, Laske C, Metzger CD, Munk MH, Perneczky R, Peters O, Priller J, Rauchmann BS, Roy N, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Wagner M, Wiltfang J, Düzel E, Jessen F; Delcode Study Group, Rizzoli SO, Zimmermann WH, Schulze TG, Falkai P, Sananbenesi F, Fischer A (2021). A microRNA signature that correlates with cognition and is a target against cognitive decline. EMBO Mol Med.2021 Oct 11:e13659. doi: 10.15252/emmm.202013659. Online ahead of print. PMID: 34633146
  • Marchant NL, Barnhofer T, Coueron R, Wirth M, Lutz A, Arenaza-Urquijo EM, Collette F, Poisnel G, Demnitz-King H, Schild AK, Coll-Padros N, Delphin-Combe F, Whitfield T, Schlosser M, Gonneaud J, Asselineau J, Walker Z, Krolak-Salmon P, Molinuevo JL, Frison E, Chételat G, Jessen F, Klimecki OM; The Medit-Ageing Research Group (2021). Effects of a Mindfulness-Based Intervention versus Health Self-Management on Subclinical Anxiety in Older Adults with Subjective Cognitive Decline: The SCD-Well Randomized Superiority Trial. Psychother Psychosom. 2021;90(5):341-350. doi: 10.1159/000515669. Epub 2021 Apr 19. PMID: 33873195 
  • Ophey A, Krohm F, Kalbe E, Greuel A, Drzezga A, Tittgemeyer M, Timmermann L, Jessen F, Eggers C, Maier F (2021). Neural correlates and predictors of subjective cognitive decline in patients with Parkinson's disease. Neurol Sci. 2021 Nov 25. doi: 10.1007/s10072-021-05734-w. Online ahead of print. PMID: 34820745
  • Dyrba M, Hanzig M, Altenstein S, Bader S, Ballarini T, Brosseron F, Buerger K, Cantré D, Dechent P, Dobisch L, Düzel E, Ewers M, Fliessbach K, Glanz W, Haynes JD, Heneka MT, Janowitz D, Keles DB, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rauchmann B, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Weber MA, Ertl-Wagner B, Wa gner M, Wiltfang J,Jessen F, Teipel SJ; ADNI, AIBL, DELCODE study groups (2021). Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer's disease.Alzheimers Res Ther. 2021 Nov 23;13(1):191. doi: 10.1186/s13195-021-00924-2.PMID: 34814936
  • Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, Düzel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Pomara N, Preis L, Priller J, Ramírez A, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Jessen F, Heneka MT(2021). Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. J Alzheimers Dis. 2021 Dec 15. doi: 10.3233/JAD-215196. Epub ahead of print. PMID: 34924387.

Hamid Kashkar      

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • He L, Sehrawat TS, Verma VK, Navarro-Corcuera A, Sidhu G, Mauer A, Luo X, Katsumi T, Chen J, Shah S, Arab JP, Cao S, Kashkar H, Gores GJ, Malhi H, Shah VH (2021). XIAP Knockdown in Alcohol-Associated Liver Disease Models Exhibits Divergent in vitro and in vivoPhenotypes Owing to a Potential Zonal Inhibitory Role of SMAC. Front Physiol. 2021 May 7;12:664222. doi: 10.3389/fphys.2021.664222. PMID: 34025452; PMCID: PMC8138467. 
  • Geueke A, Mantellato G, Kuester F, Schettina P, Nelles M, Seeger JM, Kashkar H, Niemann C (2021). The anti-apoptotic Bcl-2 protein regulates hair follicle stem cell function. EMBO Rep. 2021 Aug 2:e52301. doi: 10.15252/embr.202052301. Epub ahead of print. PMID: 34342114. 
  • Theobald SJ, Simonis A, Georgomanolis T, Kreer C, Zehner M, Eisfeld HS, Albert MC, Chhen J, Motameny S, Erger F, Fischer J, Malin JJ, Gräb J, Winter S, Pouikli A, David F, Böll B, Koehler P, Vanshylla K, Gruell H, Suárez I, Hallek M, Fätkenheuer G, Jung N, Cornely OA, Lehmann C, Tessarz P, Altmüller J, Nürnberg P, Kashkar H, Klein F, Koch M, Rybniker J (2021). Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19. EMBO Mol Med. 2021 Aug 9;13(8):e14150. doi: 10.15252/emmm.202114150. Epub 2021 Jun 16. PMID: 34133077; PMCID: PMC8350892.
  • Theobald SJ, Gräb J, Fritsch M, Suárez I, Eisfeld HS, Winter S, Koch M, Hölscher C, Pasparakis M, Kashkar H, Rybniker J (2021). Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages. Cell Death Discov. 2021 Oct 30;7(1):327. doi: 10.1038/s41420-021-00716-5. PMID: 34718331

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Peter Kloppenburg

  • Fuscà D, Kloppenburg P (2021). Odor processing in the cockroach antennal lobe-the network components. Cell Tissue Res. 2021 Jan 23. doi: 10.1007/s00441-020-03387-3. Online ahead of print. PMID: 33486607 Review. 
  • Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC (2021). Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat Neurosci. 2021 May 17. doi: 10.1038/s41593-021-00854-0. Epub ahead of print. PMID: 34002087. 
  • Hess S, Pouzat C, Paeger L, Pippow A, Kloppenburg P (2021). Analysis of neuronal Ca2+handling properties by combining perforated patch clamp recordings and the added buffer approach. Cell Calcium. 2021 May 10;97:102411. doi: 10.1016/j.ceca.2021.102411. Epub ahead of print. PMID: 34082340.
  • Xiao X, Yeghiazaryan G, Hess S, Klemm P, Sieben A, Kleinridders A, Morgan DA, Wunderlich FT, Rahmouni K, Kong D, Scammell TE, Lowell BB, Kloppenburg P, Brüning JC,Hausen AC (2021). Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity. Nat Commun. 2021 Sep 2;12(1):5249. doi: 10.1038/s41467-021-25380-2. PMID: 34475397
  • Fusca D, Kloppenburg P (2021). Task-specific roles of local interneurons for inter- and intraglomerular signaling in the insect antennal lobe.Elife. 2021 Sep 23;10: e65217. doi: 10.7554/eLife.65217. PMID: 34554087
  • Hess S, Pouzat C, Kloppenburg P (2021). Datasets for calcium dynamics comparison between the whole-cell and a β-escin based perforated patch configuration in brain slices from adult mice. Data Brief. 2021 Oct 17;39:107494. doi: 10.1016/j.dib.2021.107494. eCollection 2021 Dec. PMID: 34754890
  • Hess S, Pouzat C, Kloppenburg P (2021). A simple method for getting standard error on the ratiometric calcium estimator. MethodsX. 2021 Oct 22;8:101548. doi: 10.1016/j.mex.2021.101548. eCollection 2021. PMID: 34754816 

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Natalia Kononenko

  • Negrete-Hurtado A, Overhoff M, Bera S, De Bruyckere E, Schätzmüller K, Kye MJ, Qin C, Lammers M, Kondylis V, Neundorf I, Kononenko N (2020). Autophagy lipidation machinery regulates axonal microtubule dynamics but is dispensable for survival of mammalian neurons. Nat Commun. 2020; 11: 1535. Published online 2020 Mar 24. doi: 10.1038/s41467-020-15287-9  
  • Overhoff M, De Bruyckere E, Kononenko NL (2020). Mechanisms of neuronal survival safeguarded by endocytosis and autophagy. J Neurochem. 2020 Sep 22. doi: 10.1111/jnc.15194. Online ahead of print. PMID: 32964462
  • Camblor-Perujo S, Kononenko NL. Brain-specific functions of the endocytic machinery. FEBS J. 2021 Apr 25. doi: 10.1111/febs.15897. Epub ahead of print. PMID: 33896112.

Thomas Krieg

  • Schumacher B, Krieg TM (2021). The Aging Skin: From Basic Mechanisms to Clinical Applications. J Invest Dermatol. 2021 Apr;141(4S):949-950. doi: 10.1016/j.jid.2020.12.002. PMID: 33752815

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Martin Krönke

  • Klimka A, Mertins S, Nicolai AK, Rummler LM, Higgins PG, Günther SD, Tosetti B, Krut O, Krönke M (2021). Epitope-specific immunity against Staphylococcus aureus coproporphyrinogen III oxidase. NPJ Vaccines. 2021 Jan 18;6(1):11. doi: 10.1038/s41541-020-00268-2. PMID: 33462229 
  • Tosetti B, Ward B, Grumme D, Herb M, Schramm M, Utermöhlen O, Heukamp LC, Krönke M, Krut O. NOX2 Deficiency Permits Sustained Survival of S. aureus in Macrophages and Contributes to Severity of Infection. Front Immunol. 2021 Mar 22;12:633629. doi: 10.3389/fimmu.2021.633629. PMID: 33868252; PMCID: PMC8044967.
  • Gluschko A, Farid A, Herb M, Grumme D, Krönke M, Schramm M (2021). Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways. Autophagy. 2021 Sep 5:1-15. doi: 10.1080/15548627.2021.1969765. Online ahead of print. PMID: 34482812

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Marcus Krüger

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • Ianni A, Kumari P, Tarighi S, Simonet NG, Popescu D, Guenther S, Hölper S, Schmidt A, Smolka C, Yue S, Krüger M, Fiorillo C, Vaquero A, Bober E, Braun T (2021). SIRT7-dependent deacetylation of NPM promotes p53 stabilization following UV-induced genotoxic stress. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2015339118. doi: 10.1073/pnas.2015339118. PMID: 33495326  
  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798
  • Abdellatif M, Trummer-Herbst V, Koser F, Durand S, Adão R, Vasques-Nóvoa F, Freundt JK, Voglhuber J, Pricolo MR, Kasa M, Türk C, Aprahamian F, Herrero-Galán E, Hofer SJ, Pendl T, Rech L, Kargl J, Anto-Michel N, Ljubojevic-Holzer S, Schipke J, Brandenberger C, Auer M, Schreiber R, Koyani CN, Heinemann A, Zirlik A, Schmidt A, von Lewinski D, Scherr D, Rainer PP, von Maltzahn J, Mühlfeld C, Krüger M, Frank S, Madeo F, Eisenberg T, Prokesch A, Leite-Moreira AF, Lourenço AP, Alegre-Cebollada J, Kiechl S, Linke WA, Kroemer G, Sedej S (2021). Nicotinamide for the treatment of heart failure with preserved ejection fraction. Sci Transl Med. 2021 Feb 10;13(580):eabd7064. doi: 10.1126/scitranslmed.abd7064
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. 2021 Feb 5;154:41-59. doi: 10.1016/j.yjmcc.2021.01.010. Online ahead of print. 
  • Leone M, Cazorla-Vázquez S, Ferrazzi F, Wiederstein JL, Gründl M, Weinstock G, Vergarajauregui S, Eckstein M, Krüger M, Gaubatz S, Engel FB (2021). IQGAP3, a YAP target, is required for proper cell cycle progression and genome stability. Mol Cancer Res. 2021 Jun 28:molcanres.MCR-20-0639-E.2020. doi: 10.1158/1541-7786.MCR-20-0639. Epub ahead of print. PMID: 34183451.  
  • Clemen CS, Schmidt A, Winter L, Canneva F, Wittig I, Becker L, Coras R, Berwanger C; German Mouse Clinic Consortium, Hofmann A, Eggers B, Marcus K, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Krüger M, von Hörsten S, Eichinger L, Schröder R (2021). N471D WASH complex subunit strumpellin knock-in mice display mild motor and cardiac abnormalities and BPTF and KLHL11 dysregulation in brain tissue. Neuropathol Appl Neurobiol. 2021 Jul 27. doi: 10.1111/nan.12750. Epub ahead of print. PMID: 34312900. 
  • Bock T, Türk C, Aravamudhan S, Keufgens L, Bloch W, Rozsivalova DH, Romanello V, Nogara L, Blaauw B, Trifunovic A, Braun T, Krüger M (2021). PERM1 interacts with the MICOS-MIB complex to connect the mitochondria and sarcolemma via ankyrin B. Nat Commun. 2021 Aug 12;12(1):4900. doi: 10.1038/s41467-021-25185-3. PMID: 34385433
  • Koyuncu S, Loureiro R, Lee HJ, Wagle P, Krueger M, Vilchez D (2021). Rewiring of the ubiquitinated proteome determines ageing in C. elegans. Nature. 2021 Aug;596(7871):285-290. doi: 10.1038/s41586-021-03781-z. Epub 2021 Jul 28. PMID: 34321666; PMCID: PMC8357631.
  • Bubb K, Holzer T, Nolte JL, Krüger M, Wilson R, Schlötzer-Schrehardt U, Brinckmann J, Altmüller J, Aszodi A, Fleischhauer L, Clausen-Schaumann H, Probst K, Brachvogel B (2021). Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage. J Biol Chem. 2021 Sep 21:101224. doi: 10.1016/j.jbc.2021.101224. Online ahead of print. PMID: 34560099
  • Klapproth S, Richter K, Türk C, Bock T, Bromberger T, Dominik J, Huck K, Pfaller K, Hess MW, Reichel CA, Krüger M, Nakchbandi IA, Moser M (2021). Low kindlin-3 levels in osteoclasts of kindlin-3 hypomorphic mice result in osteopetrosis due to leaky sealing zones. J Cell Sci. 2021 Oct 27:jcs.259040. doi: 10.1242/jcs.259040. Online ahead of print. PMID: 34704600
  • Hallenborg P, Jensen BAH, Fjære E, Petersen RK, Belmaâti MS, Rasmussen SS, Gunnarsson JP, Lauritzen P, Cheng KKY, Hermansson M, Sonne SB, Ejsing CS, Xu A, Kratchmarova I, Krüger M, Madsen L, Kristiansen K, Blagoev B (2021). Adipose MDM2 regulates systemic insulin sensitivity. Sci Rep. 2021 Nov 8;11(1):21839. doi: 10.1038/s41598-021-01240-3. PMID: 34750429 
  • Baraldo M, Nogara L, Dumitras GA, Tchampda Dondjang AH, Geremia A, Scalabrin M, Türk C, Telkamp F, Zentilin L, Giacca M, Krüger M, Blaauw B (2021). Raptor is critical for increasing the mitochondrial proteome and skeletal muscle force during hypertrophy. FASEB J. 2021 Dec;35(12):e22031. doi: 10.1096/fj.202101054RR.PMID: 34767636
  • Altman T, Ionescu A, Ibraheem A, Priesmann D, Gradus-Pery T, Farberov L, Alexandra G, Shelestovich N, Dafinca R, Shomron N, Rage F, Talbot K, Ward ME, Dori A, Krüger M, Perlson E (2021). Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins. Nat Commun. 2021 Nov 25;12(1):6914. doi: 10.1038/s41467-021-27221-8. PMID: 34824257
  • Boehm V, Kueckelmann S, Gerbracht JV, Kallabis S, Britto-Borges T, Altmüller J, Krüger M, Dieterich C, Gehring NH (2021). SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity. Nat Commun. 2021 Jun 25;12(1):3965. doi: 10.1038/s41467-021-24046-3. PMID: 34172724; PMCID: PMC8233366.
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Leo Kurian

  • Kargapolova Y, Rehimi R, Kayserili H, Brühl J, Sofiadis K, Zirkel A, Palikyras S, Mizi A, Li Y, Yigit G, Hoischen A, Frank S, Russ N, Trautwein J, van Bon B, Gilissen C, Laugsch M, Gusmao EG, Josipovic N, Altmüller J, Nürnberg P, Längst G, Kaiser FJ, Watrin E, Brunner H, Rada-Iglesias A, Kurian L, Wollnik B, Bouazoune K, Papantonis A (2021). Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology. Nat Commun. 2021 May 21;12(1):3014. doi: 10.1038/s41467-021-23327-1. PMID: 34021162; PMCID: PMC8140133.

Thomas Langer

  • Eiyama A, Aaltonen MJ, Nolte H, Tatsuta T, Langer T (2021). Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling. J Biol Chem. 2021 Jan 23:100335. doi: 10.1016/j.jbc.2021.100335. PMID: 33497623 
  • Sprenger HG, MacVicar T, Bahat A, Fiedler KU, Hermans S, Ehrentraut D, Ried K, Milenkovic D, Bonekamp N, Larsson NG, Nolte H, Giavalisco P, Langer T (2021). Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity. Nat Metab. 2021 Apr 26. doi: 10.1038/s42255-021-00385-9. Epub ahead of print. PMID: 33903774. 
  • Nolte H, Langer T. ComplexFinder: A software package for the analysis of native protein complex fractionation experiments. Biochim Biophys Acta Bioenerg. 2021 Apr 30:148444. doi: 10.1016/j.bbabio.2021.148444. Epub ahead of print. PMID: 33940038. 
  • Cretin E, Lopes P, Vimont E, Tatsuta T, Langer T, Gazi A, Sachse M, Yu-Wai-Man P, Reynier P, Wai T (2021).High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts. EMBO Mol Med. 2021 May 20:e13579. doi: 10.15252/emmm.202013579. Epub ahead of print. PMID: 34014035.
  • Willenborg S, Sanin DE, Jais A, Ding X, Ulas T, Nüchel J, Popović M, MacVicar T, Langer T, Schultze JL, Gerbaulet A, Roers A, Pearce EJ, Brüning JC, Trifunovic A, Eming SA (2021). Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab. 2021 Oct 25:S1550-4131(21)00482-4. doi: 10.1016/j.cmet.2021.10.004. Online ahead of print. PMID: 34715039
  • Murschall LM, Peker E, MacVicar T, Langer T, Riemer J (2021). Protein Import Assay into Mitochondria Isolated from Human Cells. Bio Protoc. 2021 Jun 20;11(12):e4057. doi: 10.21769/BioProtoc.4057. PMID: 34263000; PMCID: PMC8260258.
  • Bahat A, MacVicar T, Langer T (2021). Metabolism and Innate Immunity Meet at the Mitochondria. Front Cell Dev Biol. 2021 Jul 27;9:720490. doi: 10.3389/fcell.2021.720490. PMID: 34386501; PMCID: PMC8353256.
  • Willenborg S, Sanin DE, Jais A, Ding X, Ulas T, Nüchel J, Popović M, MacVicar T, Langer T, Schultze JL, Gerbaulet A, Roers A, Pearce EJ, Brüning JC, Trifunovic A, Eming SA (2021). Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab. 2021 Oct 25:S1550-4131(21)00482-4. doi: 10.1016/j.cmet.2021.10.004. Online ahead of print. PMID: 34715039
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein.  J Mol Cell Cardiol. 2021 May;154:41-59. doi: 10.1016/j.yjmcc.2021.01.010. Epub 2021 Feb 5. PMID: 33549681
  • König T, Nolte H, Aaltonen MJ, Tatsuta T, Krohls M, Stroh T, Langer T and McBride H(2021). MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control. Nat Cell Biol 2021. doi: 10.1038/s41556-021-00798-4. PMID: 34873283

Maria Leptin

  • Ding X, Kakanj P, Leptin M, Eming SA (2021). Regulation of the Wound Healing Response during Aging. J Invest Dermatol. 2021 Feb 5;S0022-202X(20)32360-5. doi: 10.1016/j.jid.2020.11.014. Online ahead of print.
  • Parisa Kakanj,Sourabh Bhide, Bernard Moussian,Maria Leptin (2021). Autophagy suppression by TORC1 maintains epithelial plasma membrane integrity and inhibits syncytium formation. bioRxiv. doi: https://doi.org/10.1101/2021.08.05.455228 the EMBO Journal, in press

Ivan Matic

  • Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagné JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehtiö L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawłowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Yélamos J, Yu X, Zaja R, Ziegler M. ADP-ribosyltransferases, an update on function and nomenclature. FEBS J. 2021 Jul 29. doi: 10.1111/febs.16142. Epub ahead of print. PMID: 34323016.
  • Michael Adams , Rahul Sharma , Thomas Colby , Felix Weis , Ivan Matic , Sagar Bhogaraju (2021). Structural basis for protein glutamylation by the Legionella pseudokinase SidJ. Nat Commun. 2021 Oct 26;12(1):6174.  doi: 10.1038/s41467-021-26429-y. PMID: 34702826
  • Yaobin Liu , Rukmini Mukherjee , Florian Bonn , Thomas Colby , Ivan Matic , Marius Glogger, Mike Heilemann, Ivan Dikic (2021). Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection.Cell Death Differ. 2021 Oct;28(10):2957-2969. doi: 10.1038/s41418-021-00830-y. Epub 2021 Jul 20.

 

 

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Roman-Ulrich Müller

  • Allmeroth K, Horn M, Kroef V, Miethe S, Müller RU, Denzel MS (2021). Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma. Leukemia.2021 Mar;35(3):887-892. doi: 10.1038/s41375-020-0989-4. Epub 2020 Jul 20. PMID: 32690882 
  • Talyan S, Filipów S, Ignarski M, Smieszek M, Chen H, Kühne L, Butt L, Göbel H, Hoyer-Allo KJR, Koehler FC, Altmüller J, Brinkkötter P, Schermer B, Benzing T, Kann M, Müller RU*, Dieterich C. CALINCA-A Novel Pipeline for the Identification of lncRNAs in Podocyte Disease. Cells. 2021 Mar 20;10(3):692. doi: 10.3390/cells10030692. PMID: 33804736; PMCID: PMC8003990. 
  • Hoyer-Allo KJR, Späth MR, Hanssen R, Johnsen M, Brodesser S, Kaufmann K, Kiefer K, Koehler FC, Göbel H, Kubacki T, Grundmann F, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2021). Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury. Int J Mol Sci. 2021 May 22;22(11):5485. doi: 10.3390/ijms22115485. PMID: 34067475; PMCID: PMC8196977.
  • Koehler FC, Späth MR, Hoyer-Allo KJR, Müller RU (2021). Mechanisms of Caloric Restriction-Mediated Stress-Resistance in Acute Kidney Injury.Nephron. 2021 Aug 2:1-5. doi: 10.1159/000517733. Epub ahead of print. PMID: 34340234.
  • Pilgram L, Eberwein L, Wille K, Koehler FC, Stecher M, Rieg S, Kielstein JT, Jakob CEM, Rüthrich M, Burst V, Prasser F, Borgmann S, Müller RU, Lanznaster J, Isberner N, Tometten L, Dolff S; LEOSS Study group (2021). Clinical course and predictive risk factors for fatal outcome of SARS-CoV-2 infection in patients with chronic kidney disease. Infection. 2021 Aug;49(4):725-737. doi: 10.1007/s15010-021-01597-7. Epub 2021 Apr 13. PMID: 33851328; PMCID: PMC8043429.
  • Di Cristanziano V, Affeldt P, Trappe M, Wirtz M, Heger E, Knops E, Kaiser R, Stippel D, Müller RU, Holtick U, Scheid C, Kann M, Kurschat CE, Grundmann F (2021). Combined Therapy with Intravenous Immunoglobulins, Letermovir and (Val-)Ganciclovir in Complicated Courses of CMV-Infection in Transplant Recipients. Microorganisms. 2021 Aug 4;9(8):1666. doi: 10.3390/microorganisms9081666. PMID: 34442744 
  • Seufert L, Benzing T, Ignarski M, Müller RU (2021). RNA-binding proteins and their role in kidney disease. Nat Rev Nephrol. 2021 Nov 3. doi: 10.1038/s41581-021-00497-1. Online ahead of print. PMID: 34732838
  • Koehler FC, Blomberg L, Brehm TT, Büttner S, Cornely OA,Degen O, Di Cristanziano V, Dolff S, Eberwein L, Hoxha E, Hoyer-Allo KJR, Rudolf S, Späth MR, Wanken M, Müller RU, Burst V (2021). Development and design of the Hantavirus registry - HantaReg - for epidemiological studies, outbreaks and clinical studies on hantavirus disease. Clin Kidney J. 2021 Mar 5;14(11):2365-2370. doi: 10.1093/ckj/sfab053. eCollection 2021 Nov. PMID: 34754431 
  • Strubl, S., Oehm, S., Torres, J.A., Grundmann, F., Haratani, J., Decker, M., Vuong, S., Kaur Bhandal, A., Methot, N., Haynie-Cion, R., Meyer, F., Siedek, F., Korst, U., Müller, R.-U. and Weimbs, T (2021) . Ketogenic Dietary Interventions in Autosomal-Dominant Polycystic Kidney Disease (ADPKD)– A Retrospective Case Series Study: First insights into Feasibility, Safety and Effects. Clinical Kidney Journal.https://doi.org/10.1093/ckj/sfab162
  • Roman-Ulrich Müller, A. Lianne Messchendorp, Henrik Birn, Giovambattista Capasso, Emilie Cornec-Le Gall, Olivier Devuyst, Albertien van Eerde, Patrick Guirchon, Tess Harris, Ewout J. Hoorn, Nine V.A.M. Knoers, Uwe Korst, Djalila Mekahli, Yannick Le Meur, Tom Nijenhuis, Albert C.M. Ong, John A. Sayer, Franz Schaefer, Aude Servais, Vladimir Tesar, Roser Torra, Stephen B. Walsh and Ron T(2021).  Gansevoort An update on the use of tolvaptan for ADPKD - Consensus statement on behalf of the ERA Working Group of Inherited Kidney Diseases (WGIKD), the European Rare Kidney Disease Reference Network (ERKNet) and Polycystic Kidney Disease International (PKD-International), 2021. Nephrology Dialysis Transplantationhttps://doi.org/10.1093/ndt/gfab312
  • Affeldt P, Koehler FC, Brensing KA, Adam V, Burian J, Butt L, Gies M, Grundmann F, Hinrichs S, Johannis W, Kalisch N, Meyer-Delpho M, Oehm S, Platen E, Schöler C, Heger E, Steger G, Stippel D, Ziegelhöfer A, Benzing T, Klein F, Kurschat C, Müller R-U*, Cristanziano VD(2021). Immune Responses to SARS-CoV-2 Infection and Vaccination in Dialysis Patients and Kidney Transplant Recipients. Microorganisms. 2022; 10(1):4. doi.org/10.3390/microorganisms10010004

Carien Niessen

  • Persa OD, Koester J, Niessen CM (2021). Regulation of Cell Polarity and Tissue Architecture in Epidermal Aging and Cancer. J Invest Dermatol. 2021 Jan 30:S0022-202X(20)32410-6. doi: 10.1016/j.jid.2020.12.012. Online ahead of print. PMID: 33531135 
  • Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernández-Baldovinos J, Zhou L, Höß C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Gröne HJ, Graumann PL, Niessen CM, Offermanns S, Wickström SA, Worzfeld T (2021). Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308. doi: 10.1038/s41467-021-21513-9. PMID: 33637728 
  • Tayem R, Niemann C, Pesch M, Morgner J, Niessen CM, Wickström SA, Aumailley M (2021). LAMININ 332 IS INDISPENSABLE FOR HOMEOSTATIC EPIDERMAL DIFFERENTIATION PROGRAMS. J Invest Dermatol. 2021 May 6:S0022-202X(21)01215-X. doi: 10.1016/j.jid.2021.04.008. Epub ahead of print. PMID: 33965403. 
  • Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B (2021). Maintaining proteostasis under mechanical stress. EMBO Rep. 2021 Aug 4;22(8):e52507. doi: 10.15252/embr.202152507. Epub 2021 Jul 26. PMID: 34309183.
  • Koehler S, Odenthal J, Ludwig V, Jess DU, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HHH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T,Iden S, Brinkkoetter PT(2021). Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int. 2021 Dec 17:S0085-2538(21)01150-9. doi: 10.1016/j.kint.2021.11.030. Epub ahead of print. PMID: 34929254. 
  • Koester J, Miroshnikova YA, Ghatak S, Chacón-Martínez CA, Morgner J, Li X, Atanassov I, Altmüller J, Birk DE, Koch M, Bloch W, Bartusel M, Niessen CM, Rada-Iglesias A, Wickström SA (2021). Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility. Nat Cell Biol. 2021 Jul;23(7):771-781. doi: 10.1038/s41556-021-00705-x. Epub 2021 Jul 8. PMID: 34239060.

Stephanie Panier

  • Klaric JA, Wüst S, Panier S (2021). New Faces of old Friends: Emerging new Roles of RNA-Binding Proteins in the DNA Double-Strand Break Response. Front Mol Biosci. 2021 May 7;8:668821. doi: 10.3389/fmolb.2021.668821. PMID: 34026839; PMCID: PMC8138124.

Linda Partridge

  • Fuentealba M, Fabian DK, Dönertaş HM, Thornton JM, Partridge L (2021). Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice. Mech Ageing Dev. 2021 Mar;194:111437. doi: 10.1016/j.mad.2021.111437. Epub 2021 Jan 14. PMID: 33454277
  • Bolukbasi E, Woodling NS, Ivanov DK, Adcott J, Foley A, Rajasingam A, Gittings LM, Aleyakpo B, Niccoli T, Thornton JM, Partridge L (2021). Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2011491118. doi: 10.1073/pnas.2011491118. PMID: 33593901
  • Fabian DK, Melike Dönertaş H, Fuentealba M, Partridge L, Thornton JM (2021). Transposable element landscape in Drosophila populations selected for longevity. Genome Biol Evol. 2021 Feb 17:evab031. doi: 10.1093/gbe/evab031. Online ahead of print. PMID: 33595657
  • Kuan V, Fraser HC, Hingorani M, Denaxas S, Gonzalez-Izquierdo A, Direk K, Nitsch D, Mathur R, Parisinos CA, Lumbers RT, Sofat R, Wong ICK, Casas JP, Thornton JM, Hemingway H, Partridge L, Hingorani AD (2021). Data-driven identification of ageing-related diseases from electronic health records. Sci Rep. 2021 Feb 3;11(1):2938. doi: 10.1038/s41598-021-82459-y. PMID: 33536532 
  • Tain LS, Sehlke R, Meilenbrock RL, Leech T, Paulitz J, Chokkalingam M, Nagaraj N, Grönke S, Fröhlich J, Atanassov I, Mann M, Beyer A, Partridge L. Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila. Elife. 2021 Apr 21;10:e67275. doi: 10.7554/eLife.67275. PMID: 33879316; PMCID: PMC8060030. 
  • Annibal A, Tharyan RG, Schonewolff MF, Tam H, Latza C, Auler MMK, Grönke S, Partridge L, Antebi A (2021). Author Correction: Regulation of the one carbon folate cycle as a shared metabolic signature of longevity. Nat Commun. 2021 Aug 12;12(1):5025. doi: 10.1038/s41467-021-24840-z. Erratum for: Nat Commun. 2021 Jun 9;12(1):3486. PMID: 34385439; PMCID: PMC8361093.
  • Nespital T, Neuhaus B, Mesaros A, Pahl A, Partridge L(2021). Lithium can mildly increase health during ageing but not lifespan in mice. Aging Cell. 2021 Oct;20(10):e13479. doi: 10.1111/acel.13479. Epub 2021 Sep 17. PMID: 34532960; PMCID: PMC8520709.
  • Li L, Conradson DM, Bharat V, Kim MJ, Hsieh CH, Minhas PS, Papakyrikos AM, Durairaj AS, Ludlam A, Andreasson KI, Partridge L, Cianfrocco MA, Wang X.(2021). A mitochondrial membrane-bridging machinery mediates signal transduction of intramitochondrial oxidation. Nat Metab. 2021 Sep;3(9):1242-1258. doi: 10.1038/s42255-021-00443-2. Epub 2021 Sep 9. PMID: 34504353; PMCID: PMC8460615.
  • Pouikli, A, Parekh, S, Maleszewska, M, Nikopoulou, C, Baghdadi, M, Tripodi, I, Folz-Donahue, K, Hinze, Y, Mesaros, A., Hoey, D, Giavalisco, P, Dowell, R, Partridge, L. & Tessarz, P. (2021). Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cells. Nature Aging. 1, 810-825.
  • Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF(2021). Autophagy in healthy aging and disease. Nat Aging. 2021 Aug;1(8):634-650. doi: 10.1038/s43587-021-00098-4. Epub 2021 Aug 12. PMID: 34901876; PMCID: PMC8659158.
  • Fabian DK, Fuentealba M, Dönertaş HM, Partridge L, Thornton JM(2021). Functional conservation in genes and pathways linking ageing and immunity. Immun Ageing. 2021 May 14;18(1):23. doi: 10.1186/s12979-021-00232-1. PMID: 33990202; PMCID: PMC8120713.
  • Lu YX, Regan JC, Eßer J, Drews LF, Weinseis T, Stinn J, Hahn O, Miller RA, Grönke S, Partridge L(2021). A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing. Elife. 2021 May 14;10:e62233. doi: 10.7554/eLife.62233. PMID: 33988501; PMCID: PMC8186904.
  • Dzankic PJ, Partridge L(2021). Clinical trials of mTOR inhibitors to boost immunity to viral infection in older adults. Lancet Healthy Longev. 2021 May;2(5):e232-e233. doi: 10.1016/S2666-7568(21)00090-8. Epub 2021 May 6. PMID: 33977282; PMCID: PMC8102037.
  • Niccoli T, Kerr F, Snoeren I, Fabian D, Aleyakpo B, Ivanov D, Sofola-Adesakin O, Cryar A, Adcott J, Thornton J, Partridge L(2021). Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity. Brain Commun. 2021 Mar 26;3(2):fcab053. doi: 10.1093/braincomms/fcab053. PMID: 33977265; PMCID: PMC8093921.
  • Dönertaş HM, Fabian DK, Valenzuela MF, Partridge L, Thornton JM(2021): Common genetic associations between age-related diseases. Nat Aging. 2021 Apr;1(4):400-412. doi: 10.1038/s43587-021-00051-5. Epub 2021 Apr 8. PMID: 33959723; PMCID: PMC7610725.
  • Baghdadi M, Hinterding HM, Partridge L, Deelen J(2021). From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing. Brief Funct Genomics. 2021 Mar 5:elab005. doi: 10.1093/bfgp/elab005. Epub ahead of print. PMID: 33690799.
  • Atilano ML, Grönke S, Niccoli T, Kempthorne L, Hahn O, Morón-Oset J, Hendrich O, Dyson M, Adams ML, Hull A, Salcher-Konrad MT, Monaghan A, Bictash M, Glaria I, Isaacs AM, Partridge L(2021). Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila. Elife. 2021 Mar 19;10:e58565. doi: 10.7554/eLife.58565. PMID: 33739284; PMCID: PMC8007214.
  • Kapetanou M, Nespital T, Tain LS, Pahl A, Partridge L, Gonos ES(2021). FoxO1 Is a Novel Regulator of 20S Proteasome Subunits Expression and Activity. Front Cell Dev Biol. 2021 Feb 5;9:625715. doi: 10.3389/fcell.2021.625715. PMID: 33634126; PMCID: PMC7901890.
  • Kaeser, S.A, Lehallier, B, Thinggaard, M, Häsler, L.M, Apel, A, Bergmann, C, Berdnik, D, Jeune, B, Christensen, K, Grönke, S, Partridge, Li, Wyss-Coray, T, Mengel-From, J & Jucker, M. (2021). A neuronal blood marker is associated with mortality in old age. Nature Aging1, 218-225.

Manolis Pasparakis  

  • Kumari S, Van TM, Preukschat D, Schuenke H, Basic M, Bleich A, Klein U, Pasparakis M (2021).NF-κB inhibition in keratinocytes causes RIPK1-mediated necroptosis and skin inflammation. Life Sci Alliance. 2021 Apr 15;4(6):e202000956. doi: 10.26508/lsa.202000956. PMID: 33858959. 
  • Oikonomou N, Schuijs MJ, Chatzigiagkos A, Androulidaki A, Aidinis V, Hammad H, Lambrecht BN, Pasparakis M(2021). Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation. Mucosal Immunol. 2021 May 27. doi: 10.1038/s41385-021-00415-5. Epub ahead of print. PMID: 34045680.
  • Schünke H, Göbel U, Dikic I, Pasparakis M (2021). OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice. Nat Commun. 2021 Oct 8;12(1):5912. doi: 10.1038/s41467-021-25945-1. PMID: 34625557
  • Theobald SJ, Gräb J, Fritsch M, Suárez I, Eisfeld HS, Winter S, Koch M, Hölscher C, Pasparakis M, Kashkar H, Rybniker J (2021). Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages. Cell Death Discov. 2021 Oct 30;7(1):327. doi: 10.1038/s41420-021-00716-5. PMID: 34718331
  • Cabeza-Cabrerizo M, Minutti CM, da Costa MP, Cardoso A, Jenkins RP, Kulikauskaite J, Buck MD, Piot C, Rogers N, Crotta S, Whittaker L, Encabo HH, McCauley JW, Allen JE, Pasparakis M, Wack A, Sahai E, Reis E Sousa C (2021). Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity. Sci Immunol. 2021 Nov 5;6(65):eabi9331. doi: 10.1126/sciimmunol.abi9331. Epub 2021 Nov 5. PMID: 34739343
  • Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, Krohn M, Körbelin J, Zhang L, Özorhan Ü, Neve V, Wagner JUG, Bojkova D, Shumliakivska M, Jiang Y, Fähnrich A, Ott F, Sencio V, Robil C, Pfefferle S, Sauve F, Coêlho CFF, Franz J, Spiecker F, Lembrich B, Binder S, Feller N, König P, Busch H, Collin L, Villaseñor R, Jöhren O, Altmeppen HC, Pasparakis M, Dimmeler S, Cinatl J, Püschel K, Zelic M, Ofengeim D, Stadelmann C, Trottein F, Nogueiras R, Hilgenfeld R, Glatzel M, Prevot V, Schwaninger M(2021). The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.Nat Neurosci. 2021 Nov;24(11):1522-1533. doi: 10.1038/s41593-021-00926-1. Epub 2021 Oct 21. PMID: 34675436 Free PMC article.
  • Hausmann A, Felmy B, Kunz L, Kroon S, Berthold DL, Ganz G, Sandu I, Nakamura T, Zangger NS, Zhang Y, Dolowschiak T, Fattinger SA, Furter M, Müller-Hauser AA, Barthel M, Vlantis K, Wachsmuth L, Kisielow J, Tortola L, Heide D, Heikenwälder M, Oxenius A, Kopf M, Schroeder T, Pasparakis M, Sellin ME, Hardt WD (2021). Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF. J Exp Med. 2021 Nov 1;218(11):e20210862. doi: 10.1084/jem.20210862. Epub 2021 Sep 16. PMID: 34529751 Free PMC article.
  • Herbert A, Wang AH, Jovin TM, Mocarski ES, Pasparakis M, Vasquez KM (2021). Concern over use of the term Z-DNA. Nature. 2021 Jun;594(7863):333. doi: 10.1038/d41586-021-01595-7. PMID: 34131341 No abstract available.
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Lena Pernas

  • Pernas L (2021). Cellular Metabolism in the Defense Against Microbes. J Cell Science. 134(5)jcs252023. doi: 10.1242/jcs.252023.PMID: 33558420. 
  • Mehra C, Pernas L (2021). Move it to lose it: Mitocytosis expels damaged mitochondria. Dev Cell. 2021 Jul 26;56(14):2014-2015. doi: 10.1016/j.devcel.2021.07.001. PMID: 34314697. 
  • Medeiros TC, Mehra C, Pernas L (2021). Contact and competition between mitochondria and microbes. Curr Opin Microbiol. 2021 Aug 16;63:189-194. doi: 10.1016/j.mib.2021.07.014. Epub ahead of print. PMID: 34411806.
  • Bean C, Audano M, Varanita T, Favaretto F, Medaglia M, Gerdol M, Pernas L, Stasi F, Giacomello M, Herkenne S, Muniandy M, Heinonen S, Cazaly E, Ollikainen M, Milan G, Pallavicini A, Pietiläinen KH, Vettor R, Mitro N, Scorrano L(2021).  The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites. Nat Metab. 2021 Dec 6. doi: 10.1038/s42255-021-00497-2. Epub ahead of print. PMID: 34873337.

Dominik Pesta

  • Strasser B, Pesta D, Rittweger J, Burtscher J, Burtscher M (2021). Nutrition for Older Athletes: Focus on Sex-Differences. Nutrients. 2021 Apr 22;13(5):1409. doi: 10.3390/nu13051409. PMID: 33922108; PMCID: PMC8143537.
  • Gratl A, Wipper S, Frese JP, Raude B, Greiner A, Pesta D. (2021). The Role of Mitochondrial Function in Peripheral Arterial Disease: Insights from Translational Studies. Int J Mol Sci. 2021 Aug 6;22(16):8478. doi: 10.3390/ijms22168478. PMID: 34445191
  • Hoppel F, Garcia-Souza LF, Kantner-Rumplmair W, Burtscher M, Gnaiger E, Pesta D,Calabria E (2021). Human Platelet Mitochondrial Function Reflects Systemic Mitochondrial Alterations: A Protocol for Application in Field Studies. Cells. 2021 Aug 14;10(8):2088. doi: 10.3390/cells10082088. PMID: 34440857
  • Pesta D, Jelenik T, Zaharia OP, Bobrov P, Görgens S, Bódis K, Karusheva Y, Krako Jakovljevic N, Lalic NM, Markgraf DF, Burkart V, Müssig K, Knebel B, Kotzka J, Eckel J, Strassburger K, Szendroedi J, Roden M (2021). NDUFB6 Polymorphism Is Associated With Physical Activity-Mediated Metabolic Changes in Type 2 Diabetes. Front Endocrinol (Lausanne). 2021 Sep 24;12:693683. doi: 10.3389/fendo.2021.693683. eCollection 2021. PMID: 34659107

Christina Polidori

  • Pickert L, Meyer AM, Becker I, Heeß A, Noetzel N, Brinkkötter P, Pilotto A, Benzing T, Polidori MC (2021). Role of a multidimensional prognosis in-hospital monitoring for older patients with prolonged stay. Int J Clin Pract. 2021 Jan 6:e13989. doi: 10.1111/ijcp.13989. Online ahead of print. PMID: 33406298
  • Polidori MC, Sies H, Ferrucci L, Benzing T(2021). COVID-19 mortality as a fingerprint of biological age. Ageing Res Rev. 2021 May;67:101308. doi: 10.1016/j.arr.2021.101308. Epub 2021 Feb 20. PMID: 33621704; PMCID: PMC7896489
  • Meyer AM, Wiebe L, Faust M, Chiapponi C, Brinkkoetter PT, Polidori MC, Bartram MP (2021). Cognitive disorder, depression and gait disturbance in an internal medicine patient-geriatric syndromes in an acute care hospital. Z Gerontol Geriatr. 2021 Feb;54(1):77-80. doi: 10.1007/s00391-020-01811-5. Epub 2020 Nov 13.
  • Kasdorf A, Dust G, Vennedey V, Rietz C, Polidori MC, Voltz R, Strupp J, CoRe Net (2021). What are the risk factors for avoidable transitions in the last year of life? A qualitative exploration of professionals' perspectives for improving care in Germany. BMC Health Serv Res. 2021 Feb 15;21(1):147. doi: 10.1186/s12913-021-06138-4. PMID: 33588851; PMCID: PMC7885553. 
  • Polidori MC, Stahl W, Griffiths HR (2021). Nutritional cognitive neuroscience of aging: Focus on carotenoids and cognitive frailty. Redox Biol. 2021 Aug;44:101996. doi: 10.1016/j.redox.2021.101996. Epub 2021 May 8. PMID: 34090844. 
  • Lagolio E, Demurtas J, Buzzetti R, Cortassa G, Bottone S, Spadafora L, Cocino C, Smith L, Benzing T, Polidori MC (2021). A rapid and feasible tool for clinical decision making in community-dwelling patients with COVID-19 and those admitted to emergency departments: the Braden-LDH-HorowITZ Assessment-BLITZ. Intern Emerg Med. 2021 Jul 28:1–6. doi: 10.1007/s11739-021-02805-w. Epub ahead of print. PMID: 34322832; PMCID: PMC8318055. 
  • Schäfer M, Körber MI, Vimalathasan R, Mauri V, Iliadis C, Metze C, Ten Freyhaus H, Baldus S, Polidori MC,Pfister R (2021). Risk Stratification of Patients Undergoing Percutaneous Repair of Mitral and Tricuspid Valves Using a Multidimensional Geriatric Assessment. Circ Cardiovasc Qual Outcomes. 2021 Aug;14(8):e007624. doi: 10.1161/CIRCOUTCOMES.120.007624. Epub 2021 Jul 30. PMID: 34325515
  • Stuckenschneider T, Abeln V, Foitschik T, Abel T, Polidori MC, Strüder HK (2021). Disease-inclusive exercise classes improve physical fitness and reduce depressive symptoms in individuals with and without Parkinson's disease-A feasibility study. Brain Behav. 2021 Sep 2:e2352. doi: 10.1002/brb3.2352. Epub ahead of print. PMID: 34472722.
  • Polidori MC, Singler K (2021). [75/f-apathy, nocturnal restlessness and mild disorientation : Preparation for the medical specialist examination: part 70]. Internist (Berl). 2021 Sep 3. doi: 10.1007/s00108-021-01091-0. Online ahead of print. PMID: 34477893.
  • von Gersdorff G, von Korn P, Duvinage A, Ihorst G, Josef A, Kaufmann M, Baer T, Fellerhoff T, Fuhrmann I, Koesel E, Zeissler S, Bobka L, Heinrich M, Schindler A, Weber R, Breuer C, Meyer AM, Polidori MC, Dinges SMT, Schoenfeld J, Siebenbuerger M, Degenhardt S, Anding-Rost K, Halle M (2021). Cluster Randomized Controlled Trial on the Effects of 12 Months of Combined Exercise Training during Hemodialysis in Patients with Chronic Kidney Disease-Study Protocol of the Dialysis Training Therapy (DiaTT) Trial. Methods Protoc. 2021 Aug 31;4(3):60. doi: 10.3390/mps4030060. PMID: 34564306.
  • Heeß A, Meyer AM, Becker I, Noetzel N, Verleysdonk J, Rarek M, Benzing T, Polidori MC (2021). The prognostic fingerprint of quality of life in older inpatients : Relationship to geriatric syndromes' and resources' profile. Z Gerontol Geriatr. 2021 Oct 6. doi: 10.1007/s00391-021-01978-5. Online ahead of print. PMID: 34617144 
  • Noetzel N, Meyer AM, Siri G, Pickert L, Heeß A, Verleysdonk J, Benzing T, Pilotto A, Barbe AG, Polidori MC (2021). The impact of oral health on prognosis of older multimorbid inpatients: the 6-month follow up MPI oral health study (MPIOH). Eur Geriatr Med. 2021 Apr;12(2):263-273. doi: 10.1007/s41999-020-00427-7. Epub 2020 Nov 18. PMID: 33206351
  • Polidori MC, Alves M, Bahat G, Boureau AS, Ozkok S, Pfister R, Pilotto A, Veronese N, Bo M; Special Interest Group “Cardiovascular Diseases” of the EuGMS (2021). Atrial fibrillation: a geriatric perspective on the 2020 ESC guidelines. Eur Geriatr Med. 2021 Nov 2:1-14. doi: 10.1007/s41999-021-00537-w. Online ahead of print. PMID: 34727362
  • Polidori MC, Friedrich C(2021).  [79/f-Fall in the bathroom without serious sequelae : Preparation for the medical specialist examination: part 90]. Internist (Berl). 2021 Nov;62(Suppl 5):580-584. German. doi: 10.1007/s00108-021-01125-7. Epub 2021 Oct 13. PMID: 34643750.

Simon Pöpsel

  • Kasinath V, Beck C, Sauer P, Poepsel S, Kosmatka J, Faini M, Toso D, Aebersold R, Nogales E (2021). JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. Science. 2021 Jan 22;371(6527):eabc3393. doi: 10.1126/science.abc3393. PMID: 33479123 
  • Finogenova K, Bonnet J, Poepsel S, Schäfer IB, Finkl K, Schmid K, Litz C, Strauss M, Benda C, Müller J. Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3. Elife. 2020 Nov 19;9:e61964. doi: 10.7554/eLife.61964. PMID: 33211010; PMCID: PMC7725500.

Alvaro Rada-Iglesias

  • Thues C, Valadas JS, Deaulmerie L, Geens A, Chouhan AK, Duran-Romaña R, Schymkowitz J, Rousseau F, Bartusel M, Rehimi R, Rada-Iglesias A, Verstreken P, Van Esch H (2021). MAPRE2 mutations result in altered human cranial neural crest migration, underlying craniofacial malformations in CSC-KT syndrome. Sci Rep. 2021 Mar 2;11(1):4976. doi: 10.1038/s41598-021-83771-3. PMID: 33654163 
  • Kargapolova Y, Rehimi R, Kayserili H, Brühl J, Sofiadis K, Zirkel A, Palikyras S, Mizi A, Li Y, Yigit G, Hoischen A, Frank S, Russ N, Trautwein J, van Bon B, Gilissen C, Laugsch M, Gusmao EG, Josipovic N, Altmüller J, Nürnberg P, Längst G, Kaiser FJ, Watrin E, Brunner H, Rada-Iglesias A, Kurian L, Wollnik B, Bouazoune K, Papantonis A (2021). Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology. Nat Commun. 2021 May 21;12(1):3014. doi: 10.1038/s41467-021-23327-1. PMID: 34021162; PMCID: PMC8140133. 
  • Koester J, Miroshnikova YA, Ghatak S, Chacón-Martínez CA, Morgner J, Li X, Atanassov I, Altmüller J, Birk DE, Koch M, Bloch W, Bartusel M, Niessen CM, Rada-Iglesias A, Wickström SA. Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility. Nat Cell Biol. 2021 Jul;23(7):771-781. doi: 10.1038/s41556-021-00705-x. Epub 2021 Jul 8. PMID: 34239060.
  • Crispatzu G, Rehimi R, Pachano T, Bleckwehl T, Cruz-Molina S, Xiao C, Mahabir E, Bazzi H, Rada-Iglesias A (2021). The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo. Nat Commun. 2021 Jul 16;12(1):4344. doi: 10.1038/s41467-021-24641-4. PMID: 34272393; PMCID: PMC8285398.
  • Pachano T, Sánchez-Gaya V, Ealo T, Mariner-Faulí M, Bleckwehl T, Asenjo HG, Respuela P, Cruz-Molina S, Muñoz-San Martín M, Haro E, van IJcken WFJ, Landeira D, Rada-Iglesias A(2021). Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness. Nat Genet. 2021 Jul;53(7):1036-1049. doi: 10.1038/s41588-021-00888-x. Epub 2021 Jun 28. PMID: 34183853
  • Bleckwehl T, Crispatzu G, Schaaf K, Respuela P, Bartusel M, Benson L, Clark SJ, Dorighi KM, Barral A, Laugsch M, van IJcken WFJ, Manzanares M, Wysocka J, Reik W, Rada-Iglesias Á (2021). Enhancer-associated H3K4 methylation safeguards in vitro germline competence. Nat Commun. 2021 Oct 1;12(1):5771. doi: 10.1038/s41467-021-26065-6.PMID: 34599190

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Alfredo Ramirez

  • Heinzel S, Kaufmann C, Grützmann R, Klawohn J, Riesel A, Bey K, Heilmann-Heimbach S, Weinhold L, Ramirez A, Wagner M, Kathmann N (2021). Polygenic risk for obsessive-compulsive disorder (OCD) predicts brain response during working memory task in OCD, unaffected relatives, and healthy controls. Sci Rep. 2021 Sep 23;11(1):18914. doi: 10.1038/s41598-021-98333-w. PMID: 34556731
  • Schönknecht YB, Crommen S, Stoffel-Wagner B, Coenen M, Fimmers R, Stehle P, Ramirez A, Egert S (2021). APOE ɛ4 Is Associated with Postprandial Inflammation in Older Adults with Metabolic Syndrome Traits. Nutrients. 2021 Nov 2;13(11):3924. doi: 10.3390/nu13113924. PMID: 34836179 
  • Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, Düzel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Pomara N, Preis L, Priller J, Ramírez A, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Jessen F, Heneka MT(2021). Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. J Alzheimers Dis. 2021 Dec 15. doi: 10.3233/JAD-215196. Epub ahead of print. PMID: 34924387.

Hans Christian Reinhardt

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • Lennartz S, Mager A, Große Hokamp N, Schäfer S, Zopfs D, Maintz D, Reinhardt HC, Thomas RK, Caldeira L, Persigehl T (2021). Texture analysis of iodine maps and conventional images for k-nearest neighbor classification of benign and metastatic lung nodules. Cancer Imaging. 2021 Jan 26;21(1):17. doi: 10.1186/s40644-020-00374-3. PMID: 33499939 
  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798 
  • Klein S, Quaas A, Quantius J, Löser H, Meinel J, Peifer M, Wagner S, Gattenlöhner S, Wittekindt C, Doeberitz MVK, Prigge ES, Langer C, Noh KW, Maltseva M, Reinhardt HC, Büttner R, Klussmann JP, Wuerdemann N (2021). Deep Learning Predicts HPV Association in Oropharyngeal Squamous Cell Carcinomas and Identifies Patients with a Favorable Prognosis Using Regular H&E Stains. Clin Cancer Res. 2021 Feb 15;27(4):1131-1138.  doi: 10.1158/1078-0432.CCR-20-3596. Epub 2020 Dec 1
  • Bebber CM, Thomas ES, Stroh J, Chen Z, Androulidaki A, Schmitt A, Höhne MN, Stüker L, de Pádua Alves C, Khonsari A, Dammert MA, Parmaksiz F, Tumbrink HL, Beleggia F, Sos ML, Riemer J,  George J, Brodesser S, Thomas RK, Reinhardt HC, von Karstedt S (2021). Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nat Commun. 2021 Apr 6;12(1):2048. doi: 10.1038/s41467-021-22336-4 
  • Jachimowicz RD, Pieper L, Reinke S, Gontarewicz A, Plütschow A, Haverkamp H, Frauenfeld L, Fend F, Overkamp M, Jochims F, Thorns C, Leo Hansmann M, Möller P, Rosenwald A, Stein H, Reinhardt HC, Borchmann P, von Tresckow B, Engert A, Klapper W (2021). Whole-slide image analysis of the tumor microenvironment identifies low B-cell content as a predictor of adverse outcome in patients with advanced-stage classical Hodgkin lymphoma treated with BEACOPP. Haematologica. 2021 Jun 1;106(6):1684-1692. doi: 10.3324/haematol.2019.243287. PMID: 32381573; PMCID: PMC8168506.
  • Farber M, Chen Y, Arnold L, Möllmann M, Boog-Whiteside E, Lin YA, Reinhardt HC,Dührsen U, Hanoun M (2021). Targeting CD38 in acute myeloid leukemia interferes with leukemia trafficking and induces phagocytosis. Sci Rep. 2021 Nov 11;11(1):22062. doi: 10.1038/s41598-021-01300-8. PMID: 34764342; PMCID: PMC8586007.
  • Leypoldt LB, Besemer B, Asemissen AM, Hänel M, Blau IW, Görner M, Ko YD, Reinhardt HC, Staib P, Mann C, Lutz R, Munder M, Graeven U, Peceny R, Salwender H, Jauch A, Zago M, Benner A, Tichy D, Bokemeyer C, Goldschmidt H, Weisel KC (2021). Isatuximab, carfilzomib, lenalidomide, and dexamethasone (Isa-KRd) in front-line treatment of high-risk multiple myeloma: interim analysis of the GMMG-CONCEPT trial. Leukemia. 2021 Nov 3. doi: 10.1038/s41375-021-01431-x. Epub ahead of print. PMID: 34732857.
  • Lindemann M, Klisanin V, Thümmler L, Fisenkci N, Tsachakis-Mück N, Ditschkowski M, Schwarzkopf S, Klump H, Reinhardt HC, Horn PA, Koldehoff M (2021). Humoral and Cellular Vaccination Responses against SARS-CoV-2 in Hematopoietic Stem Cell Transplant Recipients. Vaccines (Basel). 2021 Sep 25;9(10):1075. doi: 10.3390/vaccines9101075. PMID: 34696183; PMCID: PMC8537291.
  • Kordelas L, Buttkereit U, Heinemann FM, Horn PA, Giebel B, Beelen DW, Reinhardt HC,Rebmann V (2021). Low Soluble Programmed Cell Death Protein 1 Levels After Allogeneic Stem Cell Transplantation Predict Moderate or Severe Chronic GvHD and Inferior Overall Survival. Front Immunol. 2021 Sep 24;12:694843. doi: 10.3389/fimmu.2021.694843. PMID: 34630383; PMCID: PMC8498033.
  • Proske P, Distelmaier L, Aramayo-Singelmann C, Koliastas N, Iannaccone A, Papathanasiou M, Temme C, Klump H, Lenz V, Koldehoff M, Carpinteiro A, Reinhardt HC, Köninger A, Röth A, Yamamoto R, Dührsen U, Alashkar F(2021). Pregnancies and Neonatal Outcomes in Patients with Sickle Cell Disease (SCD): Still a (High-)Risk Constellation? J Pers Med. 2021 Aug 30;11(9):870. doi: 10.3390/jpm11090870. PMID: 34575647; PMCID: PMC8464744.
  • Schmidt J, Goergens J, Pochechueva T, Kotter A, Schwenzer N, Sitte M, Werner G, Altmüller J, Thiele H, Nürnberg P, Isensee J, Li Y, Müller C, Leube B, Reinhardt HC, Hucho T, Salinas G, Helm M, Jachimowicz RD, Wieczorek D, Kohl T, Lehnart SE, Yigit G, Wollnik B (2021). Biallelic variants in YRDC cause a developmental disorder with progeroid features. Hum Genet. 2021 Dec;140(12):1679-1693. doi: 10.1007/s00439-021-02347-3. Epub 2021 Sep 20. PMID: 34545459; PMCID: PMC8553732.
  • Pacholewska A, Grimm C, Herling CD, Lienhard M, Königs A, Timmermann B, Altmüller J, Mücke O, Reinhardt HC, Plass C, Herwig R, Hallek M, Schweiger MR.(2021). Altered DNA Methylation Profiles in SF3B1 Mutated CLL Patients. Int J Mol Sci. 2021 Aug 28;22(17):9337. doi: 10.3390/ijms22179337. PMID: 34502260; PMCID: PMC8431484.
  • von Tresckow J, von Tresckow B, Reinhardt HC, Herrmann K, Berliner C(2021). Thymic hyperplasia after mRNA based Covid-19 vaccination. Radiol Case Rep. 2021 Dec;16(12):3744-3745. doi: 10.1016/j.radcr.2021.08.050. Epub 2021 Aug 26. PMID: 34462647; PMCID: PMC8387216.
  • Baron F, Ngoya M, Labopin M, Cornelissen JJ, Ganser A, Forcade E, Sengeloev H, Socié G, Blaise D, Bornhäuser M, Valerius T, Reinhardt HC, Kröger N, Ruggeri A, Nagler A, Mohty M (2021).  Comparison of long-term outcome for AML patients alive free of disease 2 years after allogeneic hematopoietic cell transplantation with umbilical cord blood versus unrelated donor: a study from the ALWP of the EBMT. Bone Marrow Transplant. 2021 Nov;56(11):2742-2748. doi: 10.1038/s41409-021-01387-7. Epub 2021 Jul 10. PMID: 34247199.
  • Mülling N, Rosery V, Reinhardt HC, Hanoun M(2021).  Factor IX p.A37V mutation causes severe bleeding in a patient with phenprocoumon therapy. Eur J Med Res. 2021 Jun 29;26(1):63. doi: 10.1186/s40001-021-00533-7. PMID: 34187575; PMCID: PMC8243751.
  • Oubari S, Naser E, Papathanasiou M, Luedike P, Hagenacker T, Thimm A, Rischpler C, Kessler L, Kimmich C, Hegenbart U, Schönland S, Rassaf T, Reinhardt HC, Jöckel KH, Dürig J, Dührsen U, Carpinteiro A (2021). Impact of time to diagnosis on Mayo stages, treatment outcome, and survival in patients with AL amyloidosis and cardiac involvement. Eur J Haematol. 2021 Oct;107(4):449-457. doi: 10.1111/ejh.13681. Epub 2021 Jul 9. PMID: 34185342.
  • Kanne J, Hussong M, Isensee J, Muñoz-López Á, Wolffgramm J, Heß F, Grimm C, Bessonov S, Meder L, Wang J, Reinhardt HC, Odenthal M, Hucho T, Büttner R, Summerer D, Schweiger MR (2021).  Pericentromeric Satellite III transcripts induce etoposide resistance. Cell Death Dis. 2021 May 24;12(6):530. doi: 10.1038/s41419-021-03810-9. PMID: 34031359; PMCID: PMC8144429.
  • McLornan D, Eikema DJ, Czerw T, Kröger N, Koster L, Reinhardt HC, Angelucci E, Robin M, Bornhäuser M, Passweg J, Clark A, Vydra J, Blau IE, Niittyvuopio R, Platzbecker U, Cornelissen JJ, Chevallier P, Srour M, Stamatovic D, Martinez-Lopez J, de Wreede L, Hayden P, Hernández-Boluda JC, Yakoub-Agha I (2021). Trends in allogeneic haematopoietic cell transplantation for myelofibrosis in Europe between 1995 and 2018: a CMWP of EBMT retrospective analysis. Bone Marrow Transplant. 2021 Sep;56(9):2160-2172. doi: 10.1038/s41409-021-01305-x. Epub 2021 Apr 28. PMID: 33911203.
  • Subramaniam N, Bottek J, Thiebes S, Zec K, Kudla M, Soun C, de Dios Panal E, Lill JK, Pfennig A, Herrmann R, Bruderek K, Rahmann S, Brandau S, Johansson P, Reinhardt HC, Dürig J, Seiffert M, Bracht T, Sitek B, Engel DR(2021). Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections. Blood Adv. 2021 Mar 9;5(5):1259-1272. doi: 10.1182/bloodadvances.2020002949. PMID: 33651101; PMCID: PMC7948268.
  • Reimann M, Schrezenmeier J, Richter-Pechanska P, Dolnik A, Hick TP, Schleich K, Cai X, Fan DNY, Lohneis P, Maßwig S, Denker S, Busse A, Knittel G, Flümann R, Childs D, Childs L, Gätjens-Sanchez AM, Bullinger L, Rosenwald A, Reinhardt HC, Schmitt CA(2021). Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas. Blood. 2021 May 20;137(20):2785-2799. doi: 10.1182/blood.2020005244. PMID: 33232972.
  • Jachimowicz RD, Klapper W, Glehr G, Müller H, Haverkamp H, Thorns C, Hansmann ML, Möller P, Stein H, Rehberg T, von Tresckow B, Reinhardt HC, Borchmann P, Chan FC, Spang R, Scott DW, Engert A, Steidl C, Altenbuchinger M, Rosenwald A (2021). Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP. Leukemia. 2021 Dec;35(12):3589-3593. doi: 10.1038/s41375-021-01314-1. Epub 2021 Jun 10. PMID: 34112956; PMCID: PMC8632672.
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Jane Reznick

  • Reznick J, Park TJ, Lewin GR (2021). A Sweet Story of Metabolic Innovation in the Naked Mole-Rat. Adv Exp Med Biol. 2021;1319:271-286. doi: 10.1007/978-3-030-65943-1_10. PMID: 34424520. 
  • Park TJ, Smith ESJ, Reznick J, Bennett NC, Applegate DT, Larson J, Lewin GR (2021). African Naked Mole-Rats Demonstrate Extreme Tolerance to Hypoxia and Hypercapnia. Adv Exp Med Biol. . 2021;1319:255-269. doi: 10.1007/978-3-030-65943-1_9. PMID: 34424519.  
  • Lewin GR, Smith ESJ, Reznick J, Debus K, Barker AJ, Park TJ (2021). The Somatosensory World of the African Naked Mole-Rat. Adv Exp Med Biol. 2021;1319:197-220. doi: 10.1007/978-3-030-65943-1_7. PMID: 34424517.
  • Buffenstein R, Amoroso V, Andziak B, Avdieiev S, Azpurua J, Barker AJ, Bennett NC, Brieño-Enríquez MA, Bronner GN, Coen C, Delaney MA, Dengler-Crish CM, Edrey YH, Faulkes CG, Frankel D, Friedlander G, Gibney PA, Gorbunova V, Hine C, Holmes MM, Jarvis JUM, Kawamura Y, Kutsukake N, Kenyon C, Khaled WT, Kikusui T, Kissil J, Lagestee S, Larson J, Lauer A, Lavrenchenko LA, Lee A, Levitt JB, Lewin GR, Lewis Hardell KN, Lin TD, Mason MJ, McCloskey D, McMahon M, Miura K, Mogi K, Narayan V, O'Connor TP, Okanoya K, O'Riain MJ, Park TJ, Place NJ, Podshivalova K, Pamenter ME, Pyott SJ, Reznick J, Ruby JG, Salmon AB, Santos-Sacchi J, Sarko DK, Seluanov A, Shepard A, Smith M, Storey KB, Tian X, Vice EN, Viltard M, Watarai A, Wywial E, Yamakawa M, Zemlemerova ED, Zions M, Smith ESJ (2021). The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology. Biol Rev Camb Philos Soc. 2021 Sep 3. doi: 10.1111/brv.12791. Online ahead of print. PMID: 34476892

Jan Riemer

  • Peker E, Erdogan AJ, Volkov AN, Riemer J (2021). Erv1 and Cytochrome c Mediate Rapid Electron Transfer via A Collision-Type Interaction. J Mol Biol. 2021 May 8;433(15):167045. doi: 10.1016/j.jmb.2021.167045. Epub ahead of print. PMID: 33971209.

Elena Rugarli

  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. 2021 Feb 5;154:41-59.  doi: 10.1016/j.yjmcc.2021.01.010. Online ahead of print.
  • Tadepalle N, Rugarli E (2021).  Lipid Droplets in the Pathogenesis of Hereditary Spastic Paraplegia. Front Mol Biosci. 2021 May 10;8:673977. doi: 10.3389/fmolb.2021.673977. eCollection 2021.

Bernhard Schermer

  • Fabretti F, Tschernoster N, Erger F, Hedergott A, Buescher AK, Dafinger C, Reusch B, Köntges VK, Kohl S, Bartram MP, Weber LT, Thiele H, Altmueller J, Schermer B, Beck BB, Habbig S (2021). Expanding the Spectrum of FAT1 Nephropathies by Novel Mutations That Affect Hippo Signaling. Kidney Int Rep. 2021 Jan 29;6(5):1368-1378. doi: 10.1016/j.ekir.2021.01.023. PMID: 34013115; PMCID: PMC8116753.
  • Hoyer-Allo KJR, Späth MR, Hanssen R, Johnsen M, Brodesser S, Kaufmann K, Kiefer K, Koehler FC, Göbel H, Kubacki T, Grundmann F, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2021). Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury. Int J Mol Sci. 2021 May 22;22(11):5485. doi: 10.3390/ijms22115485. PMID: 34067475; PMCID: PMC8196977. 
  • Butt L, Unnersjö-Jess D, Höhne M, Schermer B, Edwards A, Benzing T (2021). A mathematical estimation of the physical forces driving podocyte detachment. Kidney Int. 2021 Jul 29:S0085-2538(21)00728-6. doi: 10.1016/j.kint.2021.06.040. Epub ahead of print. PMID: 34332959.
  • Mangold N, Pippin J, Unnersjoe-Jess D, Koehler S, Shankland S, Brähler S, Schermer B, Benzing T, Brinkkoetter PT, Hagmann H (2021). The Atypical Cyclin-Dependent Kinase 5 (Cdk5) Guards Podocytes from Apoptosis in Glomerular Disease While Being Dispensable for Podocyte Development. Cells. 2021 Sep 18;10(9):2464. doi: 10.3390/cells10092464. PMID: 34572114.
  • Reusch B, Bartram MP, Dafinger C, Palacio-Escat N, Wenzel A, Fenton RA, Saez-Rodriguez J, Schermer B, Benzing T, Altmüller J, Beck BB, Rinschen MM (2021). MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells. J Proteomics. 2021 Nov 11:104424. doi: 10.1016/j.jprot.2021.104424. Online ahead of print. PMID: 34775100
  • Schlingmann KP, Jouret F, Shen K, Nigam A, Arjona FJ, Dafinger C, Houillier P, Jones DP, Kleinerüschkamp F, Oh J, Godefroid N, Eltan M, Güran T, Burtey S, Parotte MC, König J, Braun A, Bos C, Ibars Serra M, Rehmann H, Zwartkruis FJT, Renkema KY, Klingel K, Schulze-Bahr E, Schermer B, Bergmann C, Altmüller J, Thiele H, Beck BB, Dahan K, Sabatini D, Liebau MC, Vargas-Poussou R, Knoers NVAM, Konrad M, de Baaij JHF(2021). mTOR-Activating Mutations in RRAGD Are Causative for Kidney Tubulopathy and Cardiomyopathy. J Am Soc Nephrol. 2021 Nov;32(11):2885-2899. doi: 10.1681/ASN.2021030333. Epub 2021 Oct 4. PMID: 34607910.
  • Koehler S, Odenthal J, Ludwig V, Jess DU, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HHH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T,Iden S, Brinkkoetter PT(2021). Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int. 2021 Dec 17:S0085-2538(21)01150-9. doi: 10.1016/j.kint.2021.11.030. Epub ahead of print. PMID: 34929254.

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Björn Schumacher

  • da Silva PFL, Schumacher B (2021). Principles of the Molecular and Cellular Mechanisms of Aging. J Invest Dermatol. 2021 Jan 28:S0022-202X(20)32364-2. doi: 10.1016/j.jid.2020.11.018. Online ahead of print. PMID: 33518357 
  • Meyer DH, Schumacher B (2021). BiT age: A transcriptome‐based aging clock near the theoretical limit of accuracy. Aging Cell. 2021 Mar;20(3):e13320. doi: 10.1111/acel.13320. Epub 2021 Mar 3
  • Schumacher B, Krieg TM (2021). The Aging Skin: From Basic Mechanisms to Clinical Applications. J Invest Dermatol. 2021 Apr;141(4S):949-950. doi: 10.1016/j.jid.2020.12.002. PMID: 33752815 
  • Schumacher B, Pothof J, Vijg J, Hoeijmakers JHJ (2021). The central role of DNA damage in the ageing process. Nature. 2021 Apr;592(7856):695-703. doi: 10.1038/s41586-021-03307-7. Epub 2021 Apr 28. PMID: 33911272.
  • Ou HL, Schumacher B (2021). Evaluating DNA damage response through immunofluorescence staining of primordial germ cells in Caenorhabditis elegans L1 larva. STAR Protoc. 2021 Apr 5;2(2):100441. doi: 10.1016/j.xpro.2021.100441. PMID: 33899022; PMCID: PMC8056264
  • Rieckher M, Garinis  GA, Schumacher B (2021). Molecular pathology of rare progeroid diseases. Trends Mol Med. 2021 Jul 13;S1471-4914(21)00178-7. doi: 10.1016/j.molmed.2021.06.011. Online ahead of print.

Sophie Steculorum

  • Gouveia A, de Oliveira Beleza R, Steculorum SM (2021). AgRP neuronal activity across feeding-related behaviours. Eur J Neurosci. 2021 Oct 16. doi: 10.1111/ejn.15498. Online ahead of print.PMID: 34655481.

  • Pujol C, Legrand A, Parodi L, Thomas P, Mochel F, Saracino D, Coarelli G, Croon M, Popovic M, Valet M, Villain N, Elshafie S, Issa M, Zuily S, Renaud M, Marelli-Tosi C, Legendre M, Trimouille A, Kemlin I, Mathieu S, Gleeson JG, Lamari F, Galatolo D, Alkouri R, Tse C, Rodriguez D, Ewenczyk C, Fellmann F, Kuntzer T, Blond E, El Hachimi KH, Darios F, Seyer A, Gazi AD, Giavalisco P, Perin S, Boucher JL, Le Corre L, Santorelli FM, Goizet C, Zaki MS, Picaud S, Mourier A, Steculorum SM, Mignot C, Durr A, Trifunovic A, Stevanin G. Implication of folate deficiency in CYP2U1 loss of function.J Exp Med. (2021) Nov 1;218(11):e20210846. doi: 10.1084/jem.20210846. Epub 2021 Sep 21.PMID: 34546337

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Peter Tessarz

  • Pouikli A, Tessarz P (2021). Epigenetic alterations in stem cell ageing-a promising target for age-reversing interventions?. Brief Funct Genomics. 2021 Mar 19:elab010. doi: 10.1093/bfgp/elab010. Online ahead of print. PMID: 33738480 
  • Pouikli A, Tessarz P (2021). Metabolism and chromatin: A dynamic duo that regulates development and ageing: Elucidating the metabolism-chromatin axis in bone-marrow mesenchymal stem cell fate decisions. Bioessays. 2021 Feb 25:e2000273. doi: 10.1002/bies.202000273. Online ahead of print. PMID: 33629755 
  • Allmeroth K, Kim CS, Annibal A, Pouikli A, Koester J, Derisbourg MJ, Andrés Chacón-Martínez C, Latza C, Antebi A,Tessarz P, Wickström SA, Denzel MS. N1-acetylspermidine is a determinant of hair follicle stem cell fate. J Cell Sci. 2021 May 1;134(9):jcs252767. doi: 10.1242/jcs.252767. Epub 2021 May 11. PMID: 33973637. 
  • Kochan DZ, Mawer JSP, Massen J, Tishinov K, Parekh S, Graef M, Spang A, Tessarz P (2021). The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription. J Cell Sci. 2021 Jul 14:jcs.259051. doi: 10.1242/jcs.259051. Epub ahead of print. PMID: 34259327.
  • Mawer JSP, Massen J, Reichert C, Grabenhorst N, Mylonas C, Tessarz P (2021). Nhp2 is a reader of H2AQ105me and part of a network integrating metabolism with rRNA synthesis. EMBO Rep. 2021 Aug 19:e52435. doi: 10.15252/embr.202152435. Epub ahead of print. PMID: 34409714. 
  • Theobald SJ, Simonis A, Georgomanolis T, Kreer C, Zehner M, Eisfeld HS, Albert MC, Chhen J, Motameny S, Erger F, Fischer J, Malin JJ, Gräb J, Winter S, Pouikli A, David F, Böll B, Koehler P, Vanshylla K, Gruell H, Suárez I, Hallek M, Fätkenheuer G, Jung N, Cornely OA, Lehmann C, Tessarz P, Altmüller J, Nürnberg P, Kashkar H, Klein F, Koch M, Rybniker J (2021). Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19. EMBO Mol Med. 2021 Aug 9;13(8):e14150. doi: 10.15252/emmm.202114150. Epub 2021 Jun 16. PMID: 34133077; PMCID: PMC8350892.
  • Demetriadou C, Raoukka A, Charidemou E, Mylonas C, Michael C, Parekh S, Koufaris C, Skourides P, Papageorgis P, Tessarz P, Kirmizis A (2021). Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance.Oncogene. 2021 Nov 16. doi: 10.1038/s41388-021-02113-9. Online ahead of print. PMID: 34785778
  • Pouikli A, Parekh S, Maleszewska M, Baghdadi M, Tripodi I, Nikopoulou C, Folz-Donahue K, Hinze Y, Mesaros A, Giavalisco P, Dowell R, Partridge L, Tessarz P (2021): Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cells. Nature Aging 1, 810–825

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Marc Tittgemeyer

  • Ruppert MC, Greuel A, Freigang J, Tahmasian M, Maier F, Hammes J, van Eimeren T, Timmermann L, Tittgemeyer M, Drzezga A, Eggers C (2021).  The default mode network and cognition in Parkinson's disease: A multimodal resting-state network approach. Hum Brain Mapp. 2021 Feb 27. doi: 10.1002/hbm.25393. Online ahead of print. PMID: 33638213
  • Schöbi D, Homberg F, Frässle S, Endepols H, Moran RJ, Friston KJ, Tittgemeyer M, Heinzle J, Stephan KE. Model-based prediction of muscarinic receptor function from auditory mismatch negativity responses. Neuroimage. 2021 Apr 30:118096. doi: 10.1016/j.neuroimage.2021.118096. Epub ahead of print. PMID: 33940149.
  • Borgmann D, Ciglieri E, Biglari N, Brandt C, Cremer AL, Backes H, Tittgemeyer M, Wunderlich FT, Brüning JC, Fenselau H (2021). Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metab. 2021 May 21:S1550-4131(21)00219-9. doi: 10.1016/j.cmet.2021.05.002. Epub ahead of print. PMID: 34043943. 
  • Loehrer PA, Nettersheim FS, Oehrn CR, Homberg F, Tittgemeyer M, Timmermann L, Weber I (2021). Increased prefrontal top-down control in older adults predicts motor performance and age-group association. Neuroimage. 2021 Jul 10;240:118383. doi: 10.1016/j.neuroimage.2021.118383. Epub ahead of print. PMID: 34252525.
  • Alicart H, Heldmann M, Göttlich M, Obst MA, Tittgemeyer M, Münte TF (2021). Modulation of visual processing of food by transcutaneous vagus nerve stimulation (tVNS). Brain Imaging Behav. 2021 Aug;15(4):1886-1897. doi: 10.1007/s11682-020-00382-8. PMID: 32926315
  • Borgmann D, Rigoux L, Kuzmanovic B, Edwin Thanarajah S, Münte TF, Fenselau H, Tittgemeyer M (2021). Technical Note: Modulation of fMRI brainstem responses by transcutaneous vagus nerve stimulation. Neuroimage. 2021 Sep 10; 244:118566. doi: 10.1016/j.neuroimage.2021.118566. Online ahead of print. PMID: 34509623
  • Hanssen, R, Kretschmer AC, Rigoux L, Albus K, Edwin Thanarajah S, Sitnikow T, Melzer C, Cornely OA, Brüning JC, Tittgemeyer M (2021). GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans. Mol Metab. 2021 Mar;45:101163. doi: 10.1016/j.molmet.2021.101163. Epub 2021 Jan 14. PMID: 33453418
  • Ophey A, Krohm F, Kalbe E, Greuel A, Drzezga A, Tittgemeyer M, Timmermann L, Jessen F, Eggers C, Maier F (2021). Neural correlates and predictors of subjective cognitive decline in patients with Parkinson's disease. Neurol Sci. 2021 Nov 25. doi: 10.1007/s10072-021-05734-w. Online ahead of print. PMID: 34820745
  • Steidel K, Ruppert MC, Palaghia I, Greuel A, Tahmasian M, Maier F, Hammes J, van Eimeren T, Timmermann L, Tittgemeyer M, Drzezga A, Pedrosa D, Eggers C (2021). Dopaminergic pathways and resting-state functional connectivity in Parkinson's disease with freezing of gait. Neuroimage Clin. 2021;32:102899. doi: 10.1016/j.nicl.2021.102899. Epub 2021 Nov 29. PMID: 34911202; PMCID: PMC8645514.

Aleksandra Trifunovic

  • Hofsetz E, Huesgen PF, Trifunovic A (2021). Identification of Putative Mitochondrial Protease Substrates. Methods Mol Biol. 2021;2192:313-329. doi: 10.1007/978-1-0716-0834-0_21. PMID: 33230781 
  • Szczepanowska K, Trifunovic A (2021). Tune instead of destroy: How proteolysis keeps OXPHOS in shape. Biochim Biophys Acta Bioenerg. 2021 Jan 5:148365. doi: 10.1016/j.bbabio.2020.148365. Online ahead of print. PMID: 33417924 Review 
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. 2021 Feb 4:S0022-2828(21)00025-0.PMID: 33549681
  • Silva-Pinheiro P, Pardo-Hernández C, Reyes A, Tilokani L, Mishra A, Cerutti R, Li S, Rozsivalova DH, Valenzuela S, Dogan SA, Peter B, Fernández-Silva P, Trifunovic A, Prudent J, Minczuk M, Bindoff L, Macao B, Zeviani M, Falkenberg M, Viscomi C. DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion. Nucleic Acids Res. 2021 May 6:gkab282. doi: 10.1093/nar/gkab282. Epub ahead of print. PMID: 33956154. 
  • Kaspar S, Oertlin C, Szczepanowska K, Kukat A, Senft K, Lucas C, Brodesser S, Hatzoglou M, Larsson O, Topisirovic I, Trifunovic A (2021). Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR. Sci Adv. 2021 May 26;7(22):eabf0971. doi: 10.1126/sciadv.abf0971. PMID: 34039602. 
  • Bock T, Türk C, Aravamudhan S, Keufgens L, Bloch W, Rozsivalova DH, Romanello V, Nogara L, Blaauw B, Trifunovic A, Braun T, Krüger M (2021). PERM1 interacts with the MICOS-MIB complex to connect the mitochondria and sarcolemma via ankyrin B. Nat Commun. 2021 Aug 12;12(1):4900. doi: 10.1038/s41467-021-25185-3. PMID: 34385433; PMCID: PMC8361071.
  • Giuseppe Calculli, Hyun Ju Lee, Koning Shen, Uyen Pham, Marija Herholz, Aleksandra Trifunovic, Andrew Dillin, David Vilchez (2021). Systemic regulation of mitochondria by germline proteostasis prevents protein aggregation in the soma of C. elegans. Sci Adv.  2021 Jun 25;7(26): eabg3012. doi: 10.1126/sciadv. abg3012. Print 2021 Jun. PMID: 34172445
  • Jobava R, Mao Y, Guan BJ, Hu D, Krokowski D, Chen CW, Shu XE, Chukwurah E, Wu J, Gao Z, Zagore LL, Merrick WC, Trifunovic A, Hsieh AC, Valadkhan S, Zhang Y, Qi X, Jankowsky E, Topisirovic I, Licatalosi DD, Qian SB, Hatzoglou M (2021). Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress. Mol Cell. 2021 Oct 21;81(20):4191-4208.e8. doi: 10.1016/j.molcel.2021.09.029. PMID: 34686314
  • Willenborg S, Sanin DE, Jais A, Ding X, Ulas T, Nüchel J, Popović M, MacVicar T, Langer T, Schultze JL, Gerbaulet A, Roers A, Pearce EJ, Brüning JC, Trifunovic A, Eming SA (2021). Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab. 2021 Oct 25:S1550-4131(21)00482-4. doi: 10.1016/j.cmet.2021.10.004. Online ahead of print. PMID: 34715039
  • Pujol C, Legrand A, Parodi L, Thomas P, Mochel F, Saracino D, Coarelli G, Croon M, Popovic M, Valet M, Villain N, Elshafie S, Issa M, Zuily S, Renaud M, Marelli-Tosi C, Legendre M, Trimouille A, Kemlin I, Mathieu S, Gleeson JG, Lamari F, Galatolo D, Alkouri R, Tse C, Rodriguez D, Ewenczyk C, Fellmann F, Kuntzer T, Blond E, El Hachimi KH, Darios F, Seyer A, Gazi AD, Giavalisco P, Perin S, Boucher JL, Le Corre L, Santorelli FM, Goizet C, Zaki MS, Picaud S, Mourier A, Steculorum SM, Mignot C, Durr A, Trifunovic A, Stevanin G(2021). Implication of folate deficiency in CYP2U1 loss of function. J Exp Med. 2021 Nov 1;218(11):e20210846. doi: 10.1084/jem.20210846. Epub 2021 Sep 21. PMID: 34546337; PMCID: PMC8480666.
  • Dinić M, Herholz M, Kačarević U, Radojević D, Novović K, Đokić J, Trifunović A, Golić N. (2021) Host-commensal interaction promotes health and lifespan in Caenorhabditis elegans through the activation of HLH-30/TFEB-mediated autophagy. Aging (Albany NY). 2021 Mar 26;13(6):8040-8054. doi: 10.18632/aging.202885. Epub 2021 Mar 26. PMID: 33770762; PMCID: PMC8034897.

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Achim Tresch

  • Failmezger H, Zwing N, Tresch A, Korski K, Schmich F. Computational Tumor Infiltration Phenotypes Enable the Spatial and Genomic Analysis of Immune Infiltration in Colorectal Cancer. Front Oncol. 2021 Mar 15;11:552331. doi: 10.3389/fonc.2021.552331. PMID: 33791196; PMCID: PMC8006941.

 

Mirka Uhlirova

  • Erkelenz S, Stankovic D, Mundorf J, Bresser T, Claudius A-K, Boehm V, Gehring NH, Uhlirova M (2021). Ecd promotes U5 snRNP maturation and Prp8 stability. Nucleic Acids Res. gkaa1274

Dario Valenzano

  • Cui R, Tyers AM, Malubhoy ZJ, Wisotsky S, Valdesalici S, Henriette E, Kosakovsky Pond SL, Valenzano DR(2021). Ancestral transoceanic colonization and recent population reduction in a non-annual killifish from the Seychelles archipelago. Mol Ecol. 2021 May 16. doi: 10.1111/mec.15982. Epub ahead of print. PMID: 33998095.
  • Khallaf MA, Cui R, Weißflog J, Erdogmus M, Svatoš A, Dweck HKM, Valenzano DR, Hansson BS, Knaden M. Large-scale characterization of sex pheromone communication systems in Drosophila. Nat Commun. 2021 Jul 6;12(1):4165. doi: 10.1038/s41467-021-24395-z. PMID: 34230464.

David Vilchez

  • Llamas E, Torres-Montilla S, Lee HJ, Barja MV, Schlimgen E, Dunken N, Wagle P, Werr W, Zuccaro A, Rodríguez-Concepción M, Vilchez D (2021). The intrinsic chaperone network of Arabidopsis stem cells confers protection against proteotoxic stress. Aging Cell. 2021 Aug;20(8):e13446. doi: 10.1111/acel.13446. Epub ahead of print Jul 30.PMID: 34327811; PMCID: PMC8373342

  • Koyuncu S, Loureiro R, Lee HJ, Wagle P,Krueger M, Vilchez D(2021). Rewiring of the ubiquitinated proteome determines ageing in C. elegans. Nature. 2021 Aug;596(7871):285-290. doi: 10.1038/s41586-021-03781-z. Epub 2021 Jul 28. PMID: 34321666; PMCID: PMC8357631.

  • Giuseppe Calculli, Hyun Ju Lee, Koning Shen, Uyen Pham, Marija Herholz, Aleksandra Trifunovic, Andrew Dillin, David Vilchez (2021). Systemic regulation of mitochondria by germline proteostasis prevents protein aggregation in the soma of C. elegans. Sci Adv.  2021 Jun 25;7(26): eabg3012. doi: 10.1126/sciadv. abg3012. Print 2021 Jun. PMID: 34172445 PMCID: PMC8232903.

  • Hommen F, Bilican S, Vilchez D (2021). Protein clearance strategies for disease intervention. J Neural Transm (Vienna). 2021 Oct 23:1-32. doi: 10.1007/s00702-021-02431-y. Online ahead of print. PMID: 34689261

Silvia von Karstedt

  • Bebber CM, Thomas ES, Stroh J, Chen Z, Androulidaki A, Schmitt A, Höhne MN, Stüker L, de Pádua Alves C, Khonsari A, Dammert MA, Parmaksiz F, Tumbrink HL, Beleggia F, Sos ML, Riemer J,  George J, Brodesser S, Thomas RK, Reinhardt C, von Karstedt S (2021). Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nat Commun. 2021 Apr 6;12(1):2048. doi: 10.1038/s41467-021-22336-4 
  • Willms A, Schupp H, Poelker M, Adawy A, Debus JF, Hartwig T, Krichel T, Fritsch J, Singh S, Walczak H, von Karstedt S, Schäfer H, Trauzold A (2021). TRAIL-receptor 2-a novel negative regulator of p53. Cell Death Dis. 2021 Jul 31;12(8):757. doi: 10.1038/s41419-021-04048-1. PMID: 34333527.
  • Montinaro A, Areso Zubiaur I, Saggau J, Kretz AL, Ferreira RMM, Hassan O, Kitzig E, Müller I, El-Bahrawy MA, von Karstedt S, Kulms D, Liccardi G, Lemke J, Walczak H (2021). Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers. Cell Death Differ. 2021 Sep 17. doi: 10.1038/s41418-021-00869-x. Online ahead of print. PMID: 34535764
  • Brägelmann J, Lorenz C, Borchmann S, Nishii K, Wegner J, Meder L, Ostendorp J, Ast DF, Heimsoeth A, Nakasuka T, Hirabae A, Okawa S, Dammert MA, Plenker D, Klein S, Lohneis P, Gu J, Godfrey LK, Forster J, Trajkovic-Arsic M, Zillinger T, Haarmann M, Quaas A, Lennartz S, Schmiel M, D'Rozario J, Thomas ES, Li H, Schmitt CA, George J, Thomas RK, von Karstedt S, Hartmann G, Büttner R, Ullrich RT, Siveke JT, Ohashi K, Schlee M, Sos ML (2021). MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nat Commun. 2021 Sep 17;12(1):5505. doi: 10.1038/s41467-021-25728-8. PMID: 34535668
  • Bebber CM, von Karstedt S (2021). Non-neuroendocrine differentiation generates a ferroptosis-prone lipidome in small cell lung cancer (SCLC). Mol Cell Oncol. 2021 Jul 5;8(4):1933871. doi: 10.1080/23723556.2021.1933871. eCollection 2021. PMID: 34616869

Johannes Vogt

  • Ye L, Ji H, Liu J, Tu CH, Kappl M, Koynov K, Vogt J*#, Butt HJ (2021). Carbon Nanotube-Hydrogel Composites Facilitate Neuronal Differentiation While Maintaining Homeostasis of Network Activity. Adv Mater. 2021 Aug 27:e2102981. doi: 10.1002/adma.202102981. Online ahead of print. PMID: 34453367
  • Fischer C, Endle H, Schumann L, Wilken-Schmitz A, Kaiser J, Gerber S, Vogelaar CF, Schmidt MHH, Nitsch R, Snodgrass I, Thomas D, Vogt J*, Tegeder I*(2021). Prevention of age-associated neuronal hyperexcitability with improved learning and attention upon knockout or antagonism of LPAR2. Cell Mol Life Sci. 2021 Feb;78(3):1029-1050. doi: 10.1007/s00018-020-03553-4. Epub 2020 May 28.
  • Iwama T, Kano K, Saigusa D, Ekroos K, van Echten-Deckert G, Vogt J, Aoki J(2021). Development of an On-Tissue Derivatization Method for MALDI Mass Spectrometry Imaging of Bioactive Lipids Containing Phosphate Monoester Using Phos-tag. Anal Chem. 2021 Mar 2;93(8):3867-3875. doi: 10.1021/acs.analchem.0c04479. Epub 2021 Feb 12. PMID: 33577289

Henning Walczak

  • Willms A, Schupp H, Poelker M, Adawy A, Debus JF, Hartwig T, Krichel T, Fritsch J, Singh S, Walczak H, von Karstedt S, Schäfer H, Trauzold A (2021). TRAIL-receptor 2-a novel negative regulator of p53. Cell Death Dis.2021 Jul 31;12(8):757. doi: 10.1038/s41419-021-04048-1. PMID: 34333527.
  • Montinaro A, Areso Zubiaur I, Saggau J, Kretz AL, Ferreira RMM, Hassan O, Kitzig E, Müller I, El-Bahrawy MA, von Karstedt S, Kulms D, Liccardi G, Lemke J, Walczak H (2021). Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers. Cell Death Differ. 2021 Sep 17. doi: 10.1038/s41418-021-00869-x. Online ahead of print. PMID: 34535764
  • Jain R, Zhao K, Sheridan JM, Heinlein M, Kupresanin F, Abeysekera W, Hall C, Rickard J, Bouillet P, Walczak H, Strasser A, Silke J, Gray DHD (2021). Dual roles for LUBAC signaling in thymic epithelial cell development and survival. Cell Death Differ. 2021 Oct;28(10):2946-2956. doi: 10.1038/s41418-021-00850-8. Epub. 2021 Aug 11. PMID: 34381167; PMCID: PMC8481470.

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Sara Wickström

  • Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernández-Baldovinos J, Zhou L, Höß C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Gröne HJ, Graumann PL, Niessen CM, Offermanns S, Wickström SA, Worzfeld T (2021). Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308. doi: 10.1038/s41467-021-21513-9. PMID: 33637728
  • Allmeroth K, Kim CS, Annibal A, Pouikli A, Koester J, Derisbourg MJ, Andrés Chacón-Martínez C, Latza C, Antebi A, Tessarz P, Wickström SA, Denzel MS (2021). N1-acetylspermidine is a determinant of hair follicle stem cell fate. J Cell Sci. 2021 May 1;134(9):jcs252767. doi: 10.1242/jcs.252767. Epub 2021 May 11. PMID: 33973637.
  • Tayem R, Niemann C, Pesch M, Morgner J, Niessen CM, Wickström SA, Aumailley M (2021). LAMININ 332 IS INDISPENSABLE FOR HOMEOSTATIC EPIDERMAL DIFFERENTIATION PROGRAMS. J Invest Dermatol. 2021 May 6:S0022-202X(21)01215-X. doi: 10.1016/j.jid.2021.04.008. Epub ahead of print. PMID: 33965403. 
  • Koester J, Miroshnikova YA, Ghatak S, Chacón-Martínez CA, Morgner J, Li X, Atanassov I, Altmüller J, Birk DE, Koch M, Bloch W, Bartusel M, Niessen CM, Rada-Iglesias A, Wickström SA (2021). Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility. Nat Cell Biol. 2021 Jul;23(7):771-781. doi: 10.1038/s41556-021-00705-x. Epub 2021 Jul 8. PMID: 34239060. 
  • Maki K, Nava MM, Villeneuve C, Chang M, Furukawa KS, Ushida T, Wickström SA (2021). Hydrostatic pressure prevents chondrocyte differentiation through heterochromatin remodeling. J Cell Sci. 2021 Jan 15;134(2):jcs247643. doi: 10.1242/jcs.247643. Epub 2021 Jan 27. PMID: 34432033.
  • Peters F, Wickström SA(2021). What doesn't kill you makes you differentiate. Dev Cell. 2021 Dec 20;56(24):3303-3304. doi: 10.1016/j.devcel.2021.12.002. PMID: 34932945.

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Rudolf J. Wiesner

  • Kimoloi S, Pla-Martín D, Oexner RR, Baris OR, Wiesner RJ (2021). Author Response: K320E-Twinkleskm Mice Are Genetically Heterogeneous for Secondary mtDNA Deletions Impairing Comparison With Controls. Invest Ophthalmol Vis Sci. 2021 Jan 4;62(1):13. doi: 10.1167/iovs.62.1.13. PMID: 33427853 
  • Paß T, Wiesner RJ, Pla-Martín D (2021). Selective Neuron Vulnerability in Common and Rare Diseases-Mitochondria in the Focus. Front Mol Biosci. 2021 Jun 30;8:676187. doi: 10.3389/fmolb.2021.676187. PMID: 34295920; PMCID: PMC8290884.
  • Imhof T, Rosenblatt K, Pryymachuk G, Weiland D, Noetzel N, Deschner J, Baris OR, Kimoloi S, Koch M, Wiesner RJ,Korkmaz Y (2021). Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor. Sci Rep. 2020 Dec 16;10(1):22037. doi: 10.1038/s41598-020-77954-7. PMID: 33328493 

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Andreas Wodarz

  • Rust K, Wodarz A (2021). Transcriptional Control of Apical-Basal Polarity Regulators. Int J Mol Sci. 2021 Nov 15;22(22):12340. doi: 10.3390/ijms222212340. PMID: 34830224
  • Sybille Koehler, Johanna Odenthal,Vivian Ludwig,David Unners jöJess, Martin Höhne, Christian Jüngst, Ferdi Grawe, Martin Helmstädter, Johanna L.Janku, Carsten Bergmann, Peter F.Hoyer, Henning Hagmann, Gerd Walz, Wilhelm Bloch, Carien Niessen, Bernhard Schermer, Andreas Wodarz, Barry Denholm,Thomas Benzing, Sandra Iden,Paul T.Brinkkoetter. (2021). caffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney International. DOI:https://doi.org/10.1016/j.kint.2021.11.030

 

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Thomas Wunderlich

  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798 
  • Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC (2021). Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat Neurosci. 2021 May 17. doi: 10.1038/s41593-021-00854-0. Epub ahead of print. PMID: 34002087. 
  • Borgmann D, Ciglieri E, Biglari N, Brandt C, Cremer AL, Backes H, Tittgemeyer M, Wunderlich FT, Brüning JC, Fenselau H (2021). Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism. Cell Metab. 2021 May 21:S1550-4131(21)00219-9. doi: 10.1016/j.cmet.2021.05.002. Epub ahead of print. PMID: 34043943.
  • Xiao X, Yeghiazaryan G, Hess S, Klemm P, Sieben A, Kleinridders A, Morgan DA, Wunderlich FT, Rahmouni K, Kong D, Scammell TE, Lowell BB, Kloppenburg P, Brüning JC,Hausen AC (2021). Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity. Nat Commun. 2021 Sep 2;12(1):5249. doi: 10.1038/s41467-021-25380-2. PMID: 34475397

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Branko Zevnik

  • Tröder SE, Zevnik B (2021). History of genome editing: From meganucleases to CRISPR. Lab Anim. 2021 Feb 23;23677221994613. doi: 10.1177/0023677221994613. Online ahead of print.
  • Wigger M, Tröder SE, Zevnik B(2021). A simple and economic protocol for efficient in vitro fertilization using cryopreserved mouse sperm. PLoS One. 2021 Oct 28;16(10):e0259202. doi: 10.1371/journal.pone.0259202. PMID: 34710162; PMCID: PMC8553151.

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