CECAD

Publications 2021

A B C​​​​​​ D E F G​​​​​​ H I J​​​​​​​ K​​​​​​​ L​​​​​​​ M N O P​​​​​​​ Q​​​​​​​ R​​​​​​​ S​​​​​​​ T​​​​​​​U​​​​​​​ V​​​​​​​ W​​​​​​​ X​​​​​​​ Y​​​​​​​ Z​​​​​​​​​​​​​​​​​​​​​

Adam Antebi

  • Schiffer I, Gerisch B, Kawamura K, Laboy R, Hewitt J, Denzel MS, Mori MA, Vanapalli S, Shen Y, Symmons O, Antebi A (2021). miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to affect muscle contractility upon proteotoxic challenge during ageing. biorxiv. doi: doi.org/10.1101/2021.01.21.427623

Hisham Bazzi

  • Phan TP, Maryniak AL, Boatwright CA, Lee J, Atkins A, Tijhuis A, Spierings DC, Bazzi H, Foijer F, Jordan PW, Stracker TH, Holland AJ (2021). Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway. EMBO J. 2021 Jan 4;40(1):e106118. doi: 10.15252/embj.2020106118. Epub 2020 Nov 23   
  • Xiao C, Grzonka M, Meyer-Gerards C, Mack M, Figge R, Bazzi H (2021). Gradual centriole maturation associates with the mitotic surveillance pathway in mouse development. EMBO Rep. 2021 Jan 7:e51127. doi: 10.15252/embr.202051127. Online ahead of print. PMID: 33410253

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Thomas Benzing

  • Pickert L, Meyer AM, Becker I, Heeß A, Noetzel N, Brinkkötter P, Pilotto A, Benzing T, Polidori MC (2021). Role of a multidimensional prognosis in-hospital monitoring for older patients with prolonged stay. Int J Clin Pract. 2021 Jan 6:e13989. doi: 10.1111/ijcp.13989. Online ahead of print. PMID: 33406298

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Jens Brüning  

  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798
  • Biglari N, Gaziano I, Schumacher J, Radermacher J, Paeger L, Klemm P, Chen W, Corneliussen S, Wunderlich CM, Sue M, Vollmar S, Klöckener T, Sotelo-Hitschfeld T, Abbasloo A, Edenhofer F, Reimann F, Gribble FM, Fenselau H, Kloppenburg P, Wunderlich FT, Brüning JC (2021). Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting. Nat. Neurosc. in press
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning JC, Langer T, Braun T, Krüger M (2021).Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. Feb 5;154:41-59. doi: 10.1016/j.yjmcc.2021.01.010.Online ahead of print.
  • Hanssen, R, Kretschmer AC, Rigoux L, Albus K, Edwin Thanarajah S, Sitnikow T, Melzer C, Cornely OA, Brüning JC, Tittgemeyer M (2021). GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans. Mol Metab. Jan 14;45:101163. doi: 10.1016/j.molmet.2021.101163. Online ahead of print.

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Oliver Cornely

  • Koehler P, Cornely OA, Kochanek M (2021). Bronchoscopy safety precautions for diagnosing COVID-19 associated pulmonary aspergillosis-A simulation study. Mycoses. 2021 Jan;64(1):55-59. doi: 10.1111/myc.13183. Epub 2020 Sep 26. PMID: 32918497 
  • Budin S, Salmanton-García J, Koehler P, Stemler J, Cornely OA, Mellinghoff SC (2021). Validation of the EQUAL Aspergillosis Score by analysing guideline-adherent management of invasive pulmonary aspergillosis. J Antimicrob Chemother. 2021 Jan 4:dkaa518. doi: 10.1093/jac/dkaa518. Online ahead of print. PMID: 33394007 
  • Budin S, Salmanton-García J, Koehler P, Stemler J, Cornely OA, Mellinghoff SC (2021). Validation of the EQUAL Aspergillosis Score by analysing guideline-adherent management of invasive pulmonary aspergillosis. J Antimicrob Chemother. 2021 Jan 4:dkaa518. doi: 10.1093/jac/dkaa518. Online ahead of print. PMID: 33394007 
  • Hanssen R, Kretschmer AC, Rigoux L, Albus K, Thanarajah SE, Sitnikow T, Melzer C, Cornely OA, Brüning JC, Tittgemeyer M (2021). GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans. Mol Metab. 2021 Jan 13:101163. doi: 10.1016/j.molmet.2021.101163. Online ahead of print. PMID: 33453418 
  • Christopeit M, Schmidt-Hieber M, Sprute R, Buchheidt D, Hentrich M, Karthaus M, Penack O, Ruhnke M, Weissinger F, Cornely OA, Maschmeyer G (2021). Prophylaxis, diagnosis and therapy of infections in patients undergoing high-dose chemotherapy and autologous haematopoietic stem cell transplantation. 2020 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO). Ann Hematol. 2021 Feb;100(2):321-336. doi: 10.1007/s00277-020-04297-8. Epub 2020 Oct 20. PMID: 33079221 
  • Wunsch S, Zurl C, Strohmaier H, Meinitzer A, Rabensteiner J, Posch W, Lass-Flörl C, Cornely O, Pregartner G, König E, Feierl G, Hoenigl M, Prattes J, Zollner-Schwetz I, Valentin T, Krause R (2021). Longitudinal Evaluation of Plasma Cytokine Levels in Patients with Invasive Candidiasis. J Fungi (Basel). 2021 Feb 1;7(2):101. doi: 10.3390/jof7020101. PMID: 33535593

Constantinos Demetriades

  • Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G, Genomics England Research Consortium, de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K (2021). G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling. Cell. 2021 Jan 18:S0092-8674(20)31694-9. doi: 10.1016/j.cell.2020.12.024. Online ahead of print. PMID: 33497611

Martin Denzel

  • Schiffer I, Gerisch B, Kawamura K, Laboy R, Hewitt J, Denzel MS, Mori MA, Vanapalli S, Shen Y, Symmons O, Antebi A (2021). miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to affect muscle contractility upon proteotoxic challenge during ageing. biorxiv. doi: https://doi.org/10.1101/2021.01.21.427623
  • Allmeroth K, Horn M, Kroef V, Miethe S, Müller RU, Denzel MS (2021). Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma. Leukemia.2021 Mar;35(3):887-892. doi: 10.1038/s41375-020-0989-4. Epub 2020 Jul 20. PMID: 32690882 

Sabine Eming

  • Ding X, Kakanj P, Leptin M, Eming SA (2021).. Regulation of the wound healing response during aging. J Invest Dermatol. 2021 Feb 5;S0022-202X(20)32360-5. doi: 10.1016/j.jid.2020.11.014. Online ahead of print

Lukas P. Frenzel

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798

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Henning Fenselau

  • Bozadjieva-Kramer N, Ross RA, Johnson DQ, Fenselau H, Haggerty DL, Atwood B, Lowell B, Flak JN (2021). The Role of Mediobasal Hypothalamic PACAP in the Control of Body Weight and Metabolism. Endocrinology. 2021 Jan 18:bqab012. doi: 10.1210/endocr/bqab012. Online ahead of print. PMID: 33460433.

 

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Ana J. Garcia-Saez

  • Dadsena S, Jenner A, García-Sáez AJ (2021). Mitochondrial outer membrane permeabilization at the single molecule level. Cell Mol Life Sci. 2021 Feb 12. doi: 10.1007/s00018-021-03771-4. Online ahead of print. PMID: 33576840 Review.

Michael Hallek

  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798

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Jan Hoeijmakers

  • Birkisdóttir MB, Jaarsma D, Brandt RMC, Barnhoorn S, van Vliet N, Imholz S, van Oostrom CT, Nagarajah B, Portilla Fernández E, Roks AJM, Elgersma Y, van Steeg H, Ferreira JA, Pennings JLA, Hoeijmakers JHJ, Vermeij WP, Dollé MET (2021). Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice. Aging Cell. 2021 Jan 23:e13302. doi: 10.1111/acel.13302. Online ahead of print.PMID: 33484480

Thorsten Hoppe    

  • Ottens F, Franz A, Hoppe T (2021). Build-UPS and break-downs: metabolism impacts on proteostasis and aging. Cell Death Differ. 2021 Jan 4. doi: 10.1038/s41418-020-00682-y. Online ahead of print. PMID: 33398091 Review

Sandra Iden 

  • Li M, Iden S (2021) Emerging Laminin-332‒Dependent and ‒Independent Roles for Integrin α3 in Protumorigenic Signaling. J Invest Dermatol. 2021 Apr;141(4):713-716. doi: 10.1016/j.jid.2020.08.017. PMID: 33752808

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Hamid Kashkar      

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829

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Peter Kloppenburg

  • Fuscà D, Kloppenburg P (2021). Odor processing in the cockroach antennal lobe-the network components. Cell Tissue Res. 2021 Jan 23. doi: 10.1007/s00441-020-03387-3. Online ahead of print. PMID: 33486607 Review.

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Thomas Krieg

  • Schumacher B, Krieg TM (2021). The Aging Skin: From Basic Mechanisms to Clinical Applications. J Invest Dermatol. 2021 Apr;141(4S):949-950. doi: 10.1016/j.jid.2020.12.002. PMID: 33752815

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Martin Krönke

  • Klimka A, Mertins S, Nicolai AK, Rummler LM, Higgins PG, Günther SD, Tosetti B, Krut O, Krönke M (2021). Epitope-specific immunity against Staphylococcus aureus coproporphyrinogen III oxidase. NPJ Vaccines. 2021 Jan 18;6(1):11. doi: 10.1038/s41541-020-00268-2. PMID: 33462229

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Marcus Krüger

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • Ianni A, Kumari P, Tarighi S, Simonet NG, Popescu D, Guenther S, Hölper S, Schmidt A, Smolka C, Yue S, Krüger M, Fiorillo C, Vaquero A, Bober E, Braun T (2021). SIRT7-dependent deacetylation of NPM promotes p53 stabilization following UV-induced genotoxic stress. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2015339118. doi: 10.1073/pnas.2015339118. PMID: 33495326  
  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798
  • Abdellatif M, Trummer-Herbst V, Koser F, Durand S, Adão R, Vasques-Nóvoa F, Freundt JK, Voglhuber J, Pricolo MR, Kasa M, Türk C, Aprahamian F, Herrero-Galán E, Hofer SJ, Pendl T, Rech L, Kargl J, Anto-Michel N, Ljubojevic-Holzer S, Schipke J, Brandenberger C, Auer M, Schreiber R, Koyani CN, Heinemann A, Zirlik A, Schmidt A, von Lewinski D, Scherr D, Rainer PP, von Maltzahn J, Mühlfeld C, Krüger M, Frank S, Madeo F, Eisenberg T, Prokesch A, Leite-Moreira AF, Lourenço AP, Alegre-Cebollada J, Kiechl S, Linke WA, Kroemer G, Sedej S (2021). Nicotinamide for the treatment of heart failure with preserved ejection fraction. Sci Transl Med. 2021 Feb 10;13(580):eabd7064. doi: 10.1126/scitranslmed.abd7064
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. 2021 Feb 5;154:41-59. doi: 10.1016/j.yjmcc.2021.01.010. Online ahead of print.

Thomas Langer

  • Eiyama A, Aaltonen MJ, Nolte H, Tatsuta T, Langer T (2021). Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling. J Biol Chem. 2021 Jan 23:100335. doi: 10.1016/j.jbc.2021.100335. PMID: 33497623

Maria Leptin

  • Ding X, Kakanj P, Leptin M, Eming SA (2021). Regulation of the Wound Healing Response during Aging. J Invest Dermatol. 2021 Feb 5;S0022-202X(20)32360-5. doi: 10.1016/j.jid.2020.11.014. Online ahead of print.

Roman-Ulrich Müller

 

  • Allmeroth K, Horn M, Kroef V, Miethe S, Müller RU, Denzel MS (2021). Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma. Leukemia.2021 Mar;35(3):887-892. doi: 10.1038/s41375-020-0989-4. Epub 2020 Jul 20. PMID: 32690882 

 

Carien Niessen

  • Persa OD, Koester J, Niessen CM (2021). Regulation of Cell Polarity and Tissue Architecture in Epidermal Aging and Cancer. J Invest Dermatol. 2021 Jan 30:S0022-202X(20)32410-6. doi: 10.1016/j.jid.2020.12.012. Online ahead of print. PMID: 33531135

Linda Partridge

  • Fuentealba M, Fabian DK, Dönertaş HM, Thornton JM, Partridge L (2021). Transcriptomic profiling of long- and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice. Mech Ageing Dev. 2021 Mar;194:111437. doi: 10.1016/j.mad.2021.111437. Epub 2021 Jan 14. PMID: 33454277
  • Bolukbasi E, Woodling NS, Ivanov DK, Adcott J, Foley A, Rajasingam A, Gittings LM, Aleyakpo B, Niccoli T, Thornton JM, Partridge L (2021). Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2011491118. doi: 10.1073/pnas.2011491118. PMID: 33593901
  • Fabian DK, Melike Dönertaş H, Fuentealba M, Partridge L, Thornton JM (2021). Transposable element landscape in Drosophila populations selected for longevity. Genome Biol Evol. 2021 Feb 17:evab031. doi: 10.1093/gbe/evab031. Online ahead of print. PMID: 33595657
  • Kuan V, Fraser HC, Hingorani M, Denaxas S, Gonzalez-Izquierdo A, Direk K, Nitsch D, Mathur R, Parisinos CA, Lumbers RT, Sofat R, Wong ICK, Casas JP, Thornton JM, Hemingway H, Partridge L, Hingorani AD (2021). Data-driven identification of ageing-related diseases from electronic health records. Sci Rep. 2021 Feb 3;11(1):2938. doi: 10.1038/s41598-021-82459-y. PMID: 33536532

Lena Pernas

  • Pernas, L., Cellular Metabolism in the Defense Against Microbes (2021) J Cell Science. 134(5)jcs252023. doi: 10.1242/jcs.252023.PMID: 33558420.

Christina Polidori

  • Pickert L, Meyer AM, Becker I, Heeß A, Noetzel N, Brinkkötter P, Pilotto A, Benzing T, Polidori MC (2021). Role of a multidimensional prognosis in-hospital monitoring for older patients with prolonged stay. Int J Clin Pract. 2021 Jan 6:e13989. doi: 10.1111/ijcp.13989. Online ahead of print. PMID: 33406298

Simon Pöpsel

  • Kasinath V, Beck C, Sauer P, Poepsel S, Kosmatka J, Faini M, Toso D, Aebersold R, Nogales E (2021). JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. Science. 2021 Jan 22;371(6527):eabc3393. doi: 10.1126/science.abc3393. PMID: 33479123

Hans Christian Reinhardt

  • Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. PMID: 33447829 
  • Lennartz S, Mager A, Große Hokamp N, Schäfer S, Zopfs D, Maintz D, Reinhardt HC, Thomas RK, Caldeira L, Persigehl T (2021). Texture analysis of iodine maps and conventional images for k-nearest neighbor classification of benign and metastatic lung nodules. Cancer Imaging. 2021 Jan 26;21(1):17. doi: 10.1186/s40644-020-00374-3. PMID: 33499939 
  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798 
  • Klein S, Quaas A, Quantius J, Löser H, Meinel J, Peifer M, Wagner S, Gattenlöhner S, Wittekindt C, Doeberitz MVK, Prigge ES, Langer C, Noh KW, Maltseva M, Reinhardt HC, Büttner R, Klussmann JP, Wuerdemann N (2021). Deep Learning Predicts HPV Association in Oropharyngeal Squamous Cell Carcinomas and Identifies Patients with a Favorable Prognosis Using Regular H&E Stains. Clin Cancer Res. 2021 Feb 15;27(4):1131-1138.  doi: 10.1158/1078-0432.CCR-20-3596. Epub 2020 Dec 1

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Elena Rugarli

  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. 2021 Feb 5;154:41-59.  doi: 10.1016/j.yjmcc.2021.01.010. Online ahead of print.

Björn Schumacher

  • da Silva PFL, Schumacher B (2021). Principles of the Molecular and Cellular Mechanisms of Aging. J Invest Dermatol. 2021 Jan 28:S0022-202X(20)32364-2. doi: 10.1016/j.jid.2020.11.018. Online ahead of print. PMID: 33518357 
  • Meyer DH, Schumacher B (2021). BiT age: A transcriptome‐based aging clock near the theoretical limit of accuracy. Aging Cell. 2021 Mar;20(3):e13320. doi: 10.1111/acel.13320. Epub 2021 Mar 3
  • Schumacher B, Krieg TM (2021). The Aging Skin: From Basic Mechanisms to Clinical Applications. J Invest Dermatol. 2021 Apr;141(4S):949-950. doi: 10.1016/j.jid.2020.12.002. PMID: 33752815

Peter Tessarz

  • Pouikli A, Tessarz P (2021). Epigenetic alterations in stem cell ageing-a promising target for age-reversing interventions?. Brief Funct Genomics. 2021 Mar 19:elab010. doi: 10.1093/bfgp/elab010. Online ahead of print. PMID: 33738480

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Alexandra Trifunovic

  • Hofsetz E, Huesgen PF, Trifunovic A (2021). Identification of Putative Mitochondrial Protease Substrates. Methods Mol Biol. 2021;2192:313-329. doi: 10.1007/978-1-0716-0834-0_21. PMID: 33230781 
  • Szczepanowska K, Trifunovic A (2021). Tune instead of destroy: How proteolysis keeps OXPHOS in shape. Biochim Biophys Acta Bioenerg. 2021 Jan 5:148365. doi: 10.1016/j.bbabio.2020.148365. Online ahead of print. PMID: 33417924 Review 
  • Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M (2021). Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol. 2021 Feb 4:S0022-2828(21)00025-0.PMID: 33549681

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Achim Tresch

  • Failmezger H, Zwing N, Tresch A, Korski K, Schmich F. Computational Tumor Infiltration Phenotypes Enable the Spatial and Genomic Analysis of Immune Infiltration in Colorectal Cancer. Front Oncol. 2021 Mar 15;11:552331. doi: 10.3389/fonc.2021.552331. PMID: 33791196; PMCID: PMC8006941.

 

Mirka Uhlirova

  • Erkelenz S, Stankovic D, Mundorf J, Bresser T, Claudius A-K, Boehm V, Gehring NH, Uhlirova M (2021). Ecd promotes U5 snRNP maturation and Prp8 stability. Nucleic Acids Res. gkaa1274

Rudolf J. Wiesner

  • Kimoloi S, Pla-Martín D, Oexner RR, Baris OR, Wiesner RJ (2021). Author Response: K320E-Twinkleskm Mice Are Genetically Heterogeneous for Secondary mtDNA Deletions Impairing Comparison With Controls. Invest Ophthalmol Vis Sci. 2021 Jan 4;62(1):13. doi: 10.1167/iovs.62.1.13. PMID: 33427853

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Andreas Wodarz

  • Witte L, Linnemannstöns K, Schmidt K, Honemann-Capito M, Grawe F, Wodarz A, Gross JC (2021).The kinesin motor Klp98A mediates apical to basal Wg transport.  Development. 2020 Aug 14;147(15):dev186833. doi: 10.1242/dev.186833.PMID: 32665246  
  • Linnemannstöns K, Witte L, Karuna M P, Kittel JC, Danieli A, Müller D, Nitsch L, Honemann-Capito M, Grawe F, Wodarz A, Gross JC (2021). Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium. Development. 2020 Aug 14;147(15):dev185421. doi: 10.1242/dev.185421. PMID: 32611603 

 

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Thomas Wunderlich

  • Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT (2021). Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. PMID: 33538798

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Branko Zevnik

  • Tröder SE, Zevnik B (2021). History of genome editing: From meganucleases to CRISPR. Lab Anim. 2021 Feb 23;23677221994613. doi: 10.1177/0023677221994613. Online ahead of print.

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