Publications 2022

AB C​​​​​​​ D E F G​​​​​​​ H I J​​​​​​​ K​​​​​​​ L​​​​​​​ M N O P​​​​​​​ Q​​​​​​​ R​​​​​​​ S​​​​​​​ T​​​​​​​ U​​​​​​​ V​​​​​​​ W​​​​​​​ X​​​​​​​ Y​​​​​​​ Z​​​​​​​​​​​​​​​​​​​​​

Adam Antebi

  • Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T,Schermer B, Schwarz G, Burst V, Müller RU (2022). A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism. Transl Res. 2022 Feb 18:S1931-5244(22)00023-8. doi: 10.1016/j.trsl.2022.02.003. Epub ahead of print. PMID: 35189406.
  • Wang X, Jiang Q, Song Y, He Z, Zhang H, Song M, Zhang X, Dai Y, Karalay O, Dieterich C, Antebi A, Wu L, Han JJ, Shen Y (2022). Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans. EMBO J. 2022 Apr 19;41(8):e109633. doi: 10.15252/embj.2021109633. Epub 2022 Mar 7. PMID: 35253240.
  • Ravanelli S, Li Q, Annibal A, Trifunovic A, Antebi A, Hoppe T (2022). Reprograming of proteasomal degradation by branched chain amino acid metabolism. Aging Cell. 2022 Sep 27:e13725. doi: 10.1111/acel.13725. Epub ahead of print. PMID: 36168305.

Miguel A. Alejandre Alcazar

  • Obst S, Herz J, Alejandre Alcazar MA, Endesfelder S, Möbius MA, Rüdiger M, Felderhoff-Müser U, Bendix I (2022). Perinatal Hyperoxia and Developmental Consequences on the Lung-Brain Axis. Oxid Med Cell Longev. 2022 Feb 24;2022:5784146. doi: 10.1155/2022/5784146. PMID: 35251477; PMCID: PMC8894035.
  • Trojan T, Alejandre Alcazar MA, Fink G, Thomassen JC, Maessenhausen MV, Rietschel E, Schneider PM, van Koningsbruggen-Rietschel S (2022). The effect of TGF-β1 polymorphisms on pulmonary disease progression in patients with cystic fibrosis.BMC Pulm Med. 2022 May 7;22(1):183. doi: 10.1186/s12890-022-01977-1. PMID: 35525938; PMCID: PMC9080196.
  • Kasper P, Selle J, Vohlen C, Wilke R, Kuiper-Makris C, Klymenko O, Bae-Gartz I, Schömig C, Quaas A,Schumacher B, Demir M, Bürger M, Lang S, Martin A, Steffen HM, Goeser T, Dötsch J, Alcazar MAA (2022). Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice. Int J Mol Sci. 2022 May 17;23(10):5609. doi: 10.3390/ijms23105609. PMID: 35628414; PMCID: PMC9144113.
  • Selle J, Dinger K, Jentgen V, Zanetti D, Will J, Georgomanolis T, Vohlen C, Wilke R, Kojonazarov B, Klymenko O, Mohr J, V Koningsbruggen-Rietschel S, Rhodes CJ, Ulrich A, Hirani D, Nestler T, Odenthal M, Mahabir E, Nayakanti S, Dabral S, Wunderlich T, Priest J, Seeger W, Dötsch J, Pullamsetti SS, Alejandre Alcazar MA (2022). Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. Nat Commun. Jul 27;13(1):4352. doi: 10.1038/s41467-022-31655-z. PMID: 35896539; PMCID: PMC9329333.
  • Voggel J, Fink G, Zelck M, Wohlfarth M, Post JM, Bindila L, Rauh M, Amann K, Alejandre Alcázar MA, Dötsch J, Nüsken KD, Nüsken E (2022). Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats. J Lipid Res. 2022 Sep 21;63(11):100283. doi: 10.1016/j.jlr.2022.100283. Epub ahead of print. PMID: 36152882; PMCID: PMC9619183.

Matteo Bergami

  • Wani GA, Sprenger HG, Ndoci K, Chandragiri S, Acton RJ, Schatton D, Kochan SMV, Sakthivelu V, Jevtic M, Seeger JM, Müller S, Giavalisco P, Rugarli EI, Motori E, Langer T,Bergami M (2022). Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.Cell Rep. 2022 Feb 15;38(7):110370. doi: 10.1016/j.celrep.2022.110370. PMID: 35172139.

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Thomas Benzing

  • Butt L, Unnersjö-Jess D, Höhne M, Hahnfeldt R, Reilly D, Rinschen MM, Plagmann I, Diefenhardt P, Brähler S, Brinkkötter PT, Brismar H, Blom H, Schermer B, Benzing T (2022). Super-Resolution Imaging of the Filtration Barrier Suggests a Role for Podocin R229Q in Genetic Predisposition to Glomerular Disease. J Am Soc Nephrol. 2022 Jan;33(1):138-154. doi: 10.1681/ASN.2020060858. Epub 2021 Dec 1. PMID: 34853150.
  • Heeß A, Meyer AM, Becker I, Noetzel N, Verleysdonk J, Rarek M, Benzing T, Polidori MC (2021). The prognostic fingerprint of quality of life in older inpatients : Relationship to geriatric syndromes' and resources' profile. Z Gerontol Geriatr. 2022 Feb;55(1):38-43. English. doi: 10.1007/s00391-021-01978-5. Epub 2021 Oct 6. PMID: 34617144.
  • Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T,Schermer B, Schwarz G, Burst V, Müller RU (2022). A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism. Transl Res. 2022 Feb 18:S1931-5244(22)00023-8. doi: 10.1016/j.trsl.2022.02.003. Epub ahead of print. PMID: 35189406. 
  • Reusch B, Bartram MP, Dafinger C, Palacio-Escat N, Wenzel A, Fenton RA, Saez-Rodriguez J, Schermer B, Benzing T, Altmüller J, Beck BB, Rinschen MM (2022). MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells. J Proteomics. 2022 Feb 10;252:104424. doi: 10.1016/j.jprot.2021.104424. Epub 2021 Nov 12. PMID: 34775100. 
  • Meyer AM, Pickert L, Heeß A, Becker I, Kurschat C, Bartram MP, Benzing T, Polidori MC (2022). Prognostic Signature of Chronic Kidney Disease in Advanced Age: Secondary Analysis from the InGAH Study with One-Year Follow-Up. Biomolecules. 2022 Mar 9;12(3):423. doi: 10.3390/biom12030423. PMID: 35327615; PMCID: PMC8946591.
  • Hoyer-Allo KJR, Späth MR, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Brönneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler FC, Grundmann F, Hackl MJ, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2022). Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney Int. 2022 May 30:S0085-2538(22)00386-6. doi: 10.1016/j.kint.2022.04.033. Epub ahead of print. PMID: 35654224.
  • Osterholt T, Gloistein C, Todorova P, Becker I, Arenskrieger K, Melka R, Koehler FC, Faust M, Wahlers T, Benzing T, Müller RU, Grundmann F, Burst V (2022). Preoperative Short-Term Restriction of Sulfur-Containing Amino Acid Intake for Prevention of Acute Kidney Injury After Cardiac Surgery: A Randomized, Controlled, Double-Blind, Translational Trial. J Am Heart Assoc. 2022 Sep 6;11(17):e025229. doi: 10.1161/JAHA.121.025229. Epub 2022 Sep 3. PMID: 36056721; PMCID: PMC9496445.

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Andreas Beyer

  • Leote AC, Wu X, Beyer A (2022). Regulatory network-based imputation of dropouts in single-cell RNA sequencing data. PLoS Comput Biol. 2022 Feb 17;18(2):e1009849. doi: 10.1371/journal.pcbi.1009849. PMID: 35176023; PMCID: PMC8890719.
  • Fraser HC, Kuan V, Johnen R, Zwierzyna M, Hingorani AD, Beyer A, Partridge L (2022). Biological mechanisms of aging predict age-related disease co-occurrence in patients. Aging Cell. 2022 Apr;21(4):e13524. doi: 10.1111/acel.13524. Epub 2022 Mar 8. PMID: 35259281; PMCID: PMC9009120. 
  • Huth M, Santini L, Galimberti E, Ramesmayer J, Titz-Teixeira F, Sehlke R, Oberhuemer M, Stummer S, Herzog V, Garmhausen M, Romeike M, Chugunova A, Leesch F, Holcik L, Weipoltshammer K, Lackner A, Schoefer C, von Haeseler A, Buecker C, Pauli A, Ameres SL, Smith A, Beyer A, Leeb M (2022). NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation. Genes Dev. 2022 Mar 1;36(5-6):348-367. doi: 10.1101/gad.347690.120. Epub 2022 Mar 3. PMID: 35241478; PMCID: PMC8973849.

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Jens Brüning  

  • Ramírez S, Haddad-Tóvolli R, Radosevic M, Toledo M, Pané A, Alcolea D, Ribas V, Milà-Guasch M, Pozo M, Obri A, Eyre E, Gómez-Valadés AG, Chivite I, Van Eeckhout T, Zalachoras I, Altirriba J, Bauder C, Imbernón M, Garrabou G, Garcia-Ruiz C, Nogueiras R, Soto D, Gasull X, Sandi C, Brüning JC, Fortea J, Jiménez A, Fernández-Checa JC, Claret M (2022). Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders. Cell Metab. 2022 Feb 1;34(2):269-284.e9. doi: 10.1016/j.cmet.2021.12.023. PMID: 35108514; PMCID: PMC8815774.
  • Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.
  • Hanssen R, Thanarajah SE, Tittgemeyer M, Brüning JC (2022). Obesity - A Matter of Motivation? Exp Clin Endocrinol Diabetes. 2022 Feb 18. doi: 10.1055/a-1749-4852. Epub ahead of print. PMID: 35181879.
  • Matsushita M, Awazawa M, Kobayashi N, Ikushima YM, Soeda K, Tamura-Nakano M, Muratani M, Kobayashi K, Blüher M, Brüning JC, Ueki K (2022). An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance. Cell Chem Biol. 2022 Apr 21;29(4):680-689.e6. doi: 10.1016/j.chembiol.2021.12.008. Epub 2022 Jan 4. PMID: 34986326.
  • Jais A, Brüning JC (2022). Arcuate Nucleus-Dependent Regulation of Metabolism-Pathways to Obesity and Diabetes Mellitus. Endocr Rev. 2022 Mar 9;43(2):314-328. doi: 10.1210/endrev/bnab025. PMID: 34490882; PMCID: PMC8905335. 
  • Hoyer-Allo KJR, Späth MR, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Brönneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler FC, Grundmann F, Hackl MJ, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2022). Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney Int. 2022 May 30:S0085-2538(22)00386-6. doi: 10.1016/j.kint.2022.04.033. Epub ahead of print. PMID: 35654224. 
  • Hammerschmidt P, Brüning JC (2022). Contribution of specific ceramides to obesity-associated metabolic diseases. Cell Mol Life Sci. 2022 Jul 5;79(8):395. doi: 10.1007/s00018-022-04401-3. PMID: 35789435; PMCID: PMC9252958.

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Filipe Cabreiro

  • Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.

Oliver Cornely

  • Seidel D, Simon M, Sprute R, Lubnow M, Evert K, Speer C, Seeßle J, Khatamzas E, Merle U, Behrens C, Blau IW, Enghard P, Haas CS, Steinmann J, Kurzai O, Cornely OA (2022). Results from a national survey on COVID-19-associated mucormycosis in Germany: 13 patients from six tertiary hospitals. Mycoses. 2022 Jan;65(1):103-109. doi: 10.1111/myc.13379. Epub 2021 Nov 16. PMID: 34655486; PMCID: PMC8662289.
  • Vehreschild MJGT, Ducher A, Louie T, Cornely OA, Feger C, Dane A, Varastet M, Vitry F, de Gunzburg J, Andremont A, Mentré F, Wilcox MH (2022).An open randomized multicentre Phase 2 trial to assess the safety of DAV132 and its efficacy to protect gut microbiota diversity in hospitalized patients treated with fluoroquinolones. J Antimicrob Chemother. 2022 Jan 7:dkab474. doi: 10.1093/jac/dkab474. Epub ahead of print. PMID: 35016205.
  • Hoenigl M, Seidel D, Carvalho A, Rudramurthy SM, Arastehfar A, Gangneux JP, Nasir N, Bonifaz A, Araiza J, Klimko N, Serris A, Lagrou K, Meis JF, Cornely OA, Perfect JR, White PL, Chakrabarti A; ECMM and ISHAM collaborators (2022). The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries. Lancet Microbe. 2022 Jan 25. doi: 10.1016/S2666-5247(21)00237-8. Epub ahead of print. PMID: 35098179; PMCID: PMC8789240.
  • Henze L, Buhl C, Sandherr M, Cornely OA, Heinz WJ, Khodamoradi Y, Kiderlen TR, Koehler P, Seidler A, Sprute R, Schmidt-Hieber M, von Lilienfeld-Toal M (2022). Management of herpesvirus reactivations in patients with solid tumours and hematologic malignancies: update of the Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO) on herpes simplex virus type 1, herpes simplex virus type 2, and varicella zoster virus. Ann Hematol. 2022 Mar;101(3):491-511. doi: 10.1007/s00277-021-04746-y. Epub 2022 Jan 7. PMID: 34994811; PMCID: PMC8810475.
  • Blankenheim Y, Salmanton-García J, Seifert H, Cornely OA, Koehler P (2022). Attributable mortality of candidemia at a German tertiary hospital from 1997 to 2001 before the introduction of echinocandins. Mycoses. 2022 Feb;65(2):211-221. doi: 10.1111/myc.13406. Epub 2021 Dec 8. PMID: 34847247.
  • Jeck J, Jakobs F, Kron A, Franz J, Cornely OA, Kron F (2022). A cost of illness study of COVID-19 patients and retrospective modelling of potential cost savings when administering remdesivir during the pandemic "first wave" in a German tertiary care hospital. Infection. 2022 Feb;50(1):191-201. doi: 10.1007/s15010-021-01685-8. Epub 2021 Aug 18. PMID: 34406606; PMCID: PMC8371942.
  • Bassetti M, Vena A, Giacobbe DR, Trucchi C, Ansaldi F, Antonelli M, Adamkova V, Alicino C, Almyroudi MP, Atchade E, Azzini AM, Brugnaro P, Carannante N, Peghin M, Berruti M, Carnelutti A, Castaldo N, Corcione S, Cortegiani A, Dimopoulos G, Dubler S, García-Garmendia JL, Girardis M, Cornely OA, Ianniruberto S, Kullberg BJ, Lagrou K, Lebihan C, Luzzati R, Malbrain M, Merelli M, Marques AJ, Martin-Loeches I, Mesini A, Paiva JA, Raineri SM, Rautemaa-Richardson R, Schouten J, Spapen H, Tasioudis P, Timsit JF, Tisa V, Tumbarello M, Van den Berg CHSB, Veber B, Venditti M, Voiriot G, Wauters J, Zappella N, Montravers P; from the Study Group for Infections in Critically Ill Patients (ESGCIP) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) (2022). Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study. Infect Dis Ther. 2022 Apr;11(2):827-840. doi: 10.1007/s40121-021-00585-6. Epub 2022 Feb 19. PMID: 35182353; PMCID: PMC8960530.
  • Driemeyer C, Falci DR, Hoenigl M, Cornely OA, Chakrabarti A, Gangneux JP, Segal E, Jürna-Ellam M, Matos T, Meis JF, Perfect JR, Arsenijevic VA, Mares M, Serban DE, Pasqualotto AC (2022). The current state of Clinical Mycology in Eastern and South-Eastern Europe. Med Mycol. 2022 Mar 22;60(4):myac017. doi: 10.1093/mmy/myac017. PMID: 35195256.
  • Van Braeckel E, Page I, Davidsen JR, Laursen CB, Agarwal R, Alastruey-Izquierdo A, Barac A, Cadranel J, Chakrabarti A, Cornely OA, Denning DW, Flick H, Gangneux JP, Godet C, Hayashi Y, Hennequin C, Hoenigl M, Irfan M, Izumikawa K, Koh WJ, Kosmidis C, Lange C, Lamprecht B, Laurent F, Munteanu O, Oladele R, Patterson TF, Watanabe A, Salzer HJF; and for CPAnet (2022). Treatment outcome definitions in chronic pulmonary aspergillosis: a CPAnet consensus statement. Eur Respir J. 2022 Mar 2:2102950. doi: 10.1183/13993003.02950-2021. Epub ahead of print. PMID: 35236726.
  • Jeck J, Jakobs F, Kron A, Cornely OA, Kron F (2022). Retrospective modelling of hospital bed capacities associated with the administration of remdesivir during the first wave of COVID-19 in a German metropolitan city. J Antimicrob Chemother. 2022 Feb 23;77(3):753-757. doi: 10.1093/jac/dkab432. PMID: 34849943; PMCID: PMC8690174.
  • Sprute R, Bethe U, Chen SC, Cornely OA (2022). EQUAL Trichosporon Score 2022: an ECMM score to measure QUALity of the clinical management of invasive Trichosporon infections. J Antimicrob Chemother. 2022 Mar 23:dkac085. doi: 10.1093/jac/dkac085. Epub ahead of print. PMID: 35325146.
  • Giacobbe DR, Prattes J, Wauters J, Dettori S, Signori A, Salmanton-García J, Maertens J, Bourgeois M, Reynders M, Rutsaert L, Van Regenmortel N, Lormans P, Feys S, Klimko N, Shadrivova O, Cornely OA, Rautemaa-Richardson R, Koehler P, Lagrou K, Bassetti M, Hoenigl M; ECMM-CAPA Study Group (2022).Prognostic Impact of Bronchoalveolar Lavage Fluid Galactomannan and Aspergillus Culture Results on Survival in COVID-19 Intensive Care Unit Patients: a Post Hoc Analysis from the European Confederation of Medical Mycology (ECMM) COVID-19-Associated Pulmonary Aspergillosis Study. J Clin Microbiol. 2022 Apr 20;60(4):e0229821. doi: 10.1128/jcm.02298-21. Epub 2022 Mar 24. PMID: 35321555; PMCID: PMC9020339.
  • Pagano L, Salmanton-García J, Marchesi F, López-García A, Lamure S, Itri F, Gomes-Silva M, Dragonetti G, Falces-Romero I, van Doesum J, Sili U, Labrador J, Calbacho M, Bilgin YM, Weinbergerová B, Serrano L, Ribera-Santa Susana JM, Malak S, Loureiro-Amigo J, Glenthøj A, Córdoba-Mascuñano R, Nunes-Rodrigues R, González-López TJ, Karlsson LK, Jiménez-Lorenzo MJ, Hernández-Rivas JÁ, Jaksic O, Ráčil Z, Busca A, Corradini P, Hoenigl M, Klimko N, Koehler P, Pagliuca A, Passamonti F, Cornely OA (2022).COVID-19 in vaccinated adult patients with hematological malignancies: preliminary results from EPICOVIDEHA. Blood. 2022 Mar 10;139(10):1588-1592. doi: 10.1182/blood.2021014124. PMID: 34748627; PMCID: PMC8577877.
  • Grothe J, Sprute R, Cornely OA (2022). Comment on: Nephrotoxicity of continuous amphotericin B in critically ill patients with abdominal sepsis: a retrospective analysis with propensity score matching. J Antimicrob Chemother. 2022 Mar 24:dkac098. doi: 10.1093/jac/dkac098. Epub ahead of print. PMID: 35325191.
  • Dalimot JJ, Smith IMC, Gerkrath J, Hartmann S, Cornely OA, Lee SC, Heitman J, Rickerts V (2022). Identification of Mucormycosis by Fluorescence In Situ Hybridization Targeting Ribosomal RNA in Tissue Samples. J Fungi (Basel). 2022 Mar 11;8(3):289. doi: 10.3390/jof8030289. PMID: 35330291; PMCID: PMC8949899.
  • Bonifacius A, Tischer-Zimmermann S, Santamorena MM, Mausberg P, Schenk J, Koch S, Barnstorf-Brandes J, Gödecke N, Martens J, Goudeva L, Verboom M, Wittig J, Maecker-Kolhoff B, Baurmann H, Clark C, Brauns O, Simon M, Lang P, Cornely OA, Hallek M, Blasczyk R, Seiferling D, Köhler P, Eiz-Vesper B (2022). Rapid Manufacturing of Highly Cytotoxic Clinical-Grade SARS-CoV-2-specific T Cell Products Covering SARS-CoV-2 and Its Variants for Adoptive T Cell Therapy. Front Bioeng Biotechnol. 2022 Apr 4;10:867042. doi: 10.3389/fbioe.2022.867042. PMID: 35480981; PMCID: PMC9036989.
  • Goebel H, Koeditz B, Huerta M, Kameri E, Nestler T, Kamphausen T, Friemann J, Hamdorf M, Ohrmann T, Koehler P, Cornely OA, Montesinos-Rongen M, Nicol D, Schorle H, Boor P, Quaas A, Pallasch C, Heidenreich A, von Brandenstein M (2022). COVID-19 Infection Induce miR-371a-3p Upregulation Resulting in Influence on Male Fertility. Biomedicines. 2022 Apr 6;10(4):858. doi: 10.3390/biomedicines10040858. PMID: 35453608; PMCID: PMC9033010.
  • Stemler J, de Jonge N, Skoetz N, Sinkó J, Brüggemann RJ, Busca A, Ben-Ami R, Ráčil Z, Piechotta V, Lewis R, Cornely OA (2022). Antifungal prophylaxis in adult patients with acute myeloid leukaemia treated with novel targeted therapies: a systematic review and expert consensus recommendation from the European Hematology Association. Lancet Haematol.2022 May;9(5):e361-e373. doi: 10.1016/S2352-3026(22)00073-4. PMID: 35483397.
  • Marchesi F, Salmanton-García J, Emarah Z, Piukovics K, Nucci M, López-García A, Ráčil Z, Farina F, Popova M, Zompi S, Audisio E, Ledoux MP, Verga L, Weinbergerová B, Szotkovski T, Da Silva MG, Fracchiolla N, De Jonge N, Collins G, Marchetti M, Magliano G, García-Vidal C, Biernat MM, Van Doesum J, Machado M, Demirkan F, Al-Khabori M, Žák P, Víšek B, Stoma I, Méndez GA, Maertens J, Khanna N, Espigado I, Dragonetti G, Fianchi L, Del Principe MI, Cabirta A, Ormazabal-Vélez I, Jaksic O, Buquicchio C, Bonuomo V, Batinić J, Omrani AS, Lamure S, Finizio O, Fernández N, Falces-Romero I, Blennow O, Bergantim R, Ali N, Win S, Van Praet J, Tisi MC, Shirinova A, Schönlein M, Prattes J, Piedimonte M, Petzer V, Navrátil M, Kulasekararaj A, Jindra P, Sramek J, Glenthøj A, Fazzi R, De Ramón-Sánchez C, Cattaneo C, Calbacho M, Bahr NC, El-Ashwah S, Cordoba R, Hanakova M, Zambrotta G, Sciumè M, Booth S, Rodrigues RN, Sacchi MV, García-Poutón N, Martín-González JA, Khostelidi S, Gräfe S, Rahimli L, Ammatuna E, Busca A, Corradini P, Hoenigl M, Klimko N, Koehler P, Pagliuca A, Passamonti F, Cornely OA, Pagano L. COVID-19 in adult acute myeloid leukemia patients: a long-term followup study from the European Hematology Association survey (EPICOVIDEHA). Haematologica. 2022 May 12. doi: 10.3324/haematol.2022.280847. Epub ahead of print. PMID: 35545919.
  • Koehler P, von Stillfried S, Garcia Borrega J, Fuchs F, Salmanton-García J, Pult F, Böll B, Eichenauer DA, Shimabukuro-Vornhagen A, Kurzai O, Boor P, Kochanek M, Cornely OA(2022). Aspergillus tracheobronchitis in COVID-19 patients with acute respiratory distress syndrome: a cohort study. Eur Respir J. 2022 May 5;59(5):2103142. doi: 10.1183/13993003.03142-2021. PMID: 35144992; PMCID: PMC9068972.
  • Keutmann M, Hermes G, Meinberger D, Roth A, Stemler J, Cornely OA, Klatt AR, Streichert T (2022). The ratio of serum LL-37 levels to blood leucocyte count correlates with COVID-19 severity. Sci Rep. 2022 Jun 8;12(1):9447. doi: 10.1038/s41598-022-13260-8. PMID: 35676519; PMCID: PMC9175165.
  • Salmanton-García J, Stewart FA, Heringer S, Koniordou M, Álvarez-Barco E, Argyropoulos CD, Themistocleous SC, Valle-Simón P, Spivak O, Součková L, Merakou C, Amélia Mendonça M, Joanna Davis R, Maria Azzini A, Askling HH, Vene S, Van Damme P, Steinbach A, Shiamakkides G, Seidel D, Olesen OF, Noula E, Macken A, Luís C, Leckler J, Launay O, Isitt C, Hellemans M, Frías-Iniesta J, Di Marzo R, Carcas AJ, Boustras G, Borobia AM, Barta I, Albus K, Akova M, Ochando J, Cohen-Kandli M, Jane Cox R, Husa P, Jancoriene L, Mallon P, Marques L, Mellinghoff SC, Nauclér P, Tacconelli E, Tóth K, Zaoutis TE, Zeitlinger M, Cornely OA, Pana ZD; VACCELERATE consortium (2022). VACCELERATE Volunteer Registry: A European study participant database to facilitate clinical trial enrolment. Vaccine. 2022 Jul 29;40(31):4090-4097. doi: 10.1016/j.vaccine.2022.05.022. Epub 2022 Jun 2. PMID: 35659449; PMCID: PMC9159788.
  • Hoenigl M, Sprute R, Arastehfar A, Perfect JR, Lass-Flörl C, Bellmann R, Prattes J, Thompson GR 3rd, Wiederhold NP, Al Obaidi MM, Willinger B, Arendrup MC, Koehler P, Oliverio M, Egger M, Schwartz IS, Cornely OA, Pappas PG, Krause R (2022). Invasive candidiasis: investigational drugs in the clinical development pipeline and mechanisms of action. Expert Opin Investig Drugs. 2022 Aug;31(8):795-812. doi: 10.1080/13543784.2022.2086120. Epub 2022 Jun 15. PMID: 35657026; PMCID: PMC9339492.
  • Bloos F, Held J, Kluge S, Simon P, Kogelmann K, de Heer G, Kuhn SO, Jarczak D, Motsch J, Hempel G, Weiler N, Weyland A, Drüner M, Gründling M, Meybohm P, Richter D, Jaschinski U, Moerer O, Günther U, Schädler D, Weiss R, Putensen C, Castellanos I, Kurzai O, Schlattmann P, Cornely OA, Bauer M, Thomas-Rüddel D; SepNet Study Group (2022). (1 → 3)-β-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial. Intensive Care Med. 2022 Jul;48(7):865-875. doi: 10.1007/s00134-022-06733-x. Epub 2022 Jun 16. PMID: 35708758; PMCID: PMC9273538.
  • Blennow O, Salmanton-García J, Nowak P, Itri F, Van Doesum J, López-García A, Farina F, Jaksic O, Pinczés LI, Bilgin YM, Falces-Romero I, Jiménez M, Ormazabal-Vélez I, Weinbergerová B, Duléry R, Stojanoski Z, Lahmer T, Fernández N, Hernández-Rivas JÁ, Petzer V, De Jonge N, Glenthøj A, De Ramón C, Biernat MM, Fracchiolla N, Aujayeb A, Van Praet J, Schönlein M, Méndez GA, Cattaneo C, Guidetti A, Sciumè M, Ammatuna E, Cordoba R, García-Poutón N, Gräfe S, Cabirta A, Wolf D, Nordlander A, García-Sanz R, Delia M, Berg Venemyr C, Brones C, Di Blasi R, De Kort E, Meers S, Lamure S, Serrano L, Merelli M, Coppola N, Bergantim R, Besson C, Kohn M, Petiti J, Garcia-Vidal C, Dargenio M, Danion F, Machado M, Bailén-Almorox R, Hoenigl M, Dragonetti G, Chai LYA, Kho CS, Bonanni M, Liévin R, Marchesi F, Cornely OA, Pagano L (2022). Outcome of infection with omicron SARS-CoV-2 variant in patients with hematological malignancies: An EPICOVIDEHA survey report. Am J Hematol. 2022 Aug;97(8):E312-E317. doi: 10.1002/ajh.26626. Epub 2022 Jun 28. PMID: 35702878.
  • Van Braeckel E, Page I, Davidsen JR, Laursen CB, Agarwal R, Alastruey-Izquierdo A, Barac A, Cadranel J, Chakrabarti A, Cornely OA, Denning DW, Flick H, Gangneux JP, Godet C, Hayashi Y, Hennequin C, Hoenigl M, Irfan M, Izumikawa K, Koh WJ, Kosmidis C, Lange C, Lamprecht B, Laurent F, Munteanu O, Oladele R, Patterson TF, Watanabe A, Salzer HJF; CPAnet (2022). Treatment outcome definitions in chronic pulmonary aspergillosis: a CPAnet consensus statement. Eur Respir J. 2022 Jun 9;59(6):2102950. doi: 10.1183/13993003.02950-2021. PMID: 35236726.
  • Cornely ME, Hasenberg T, Cornely OA, Ure C, Hettenhausen C, Schmidt J (2022). Persistent lipedema pain in patients after bariatric surgery: a case series of 13 patients. Surg Obes Relat Dis. 2022 May;18(5):628-633. doi: 10.1016/j.soard.2021.12.027. Epub 2022 Jan 7. PMID: 35144895.
  • Lamure S, Salmanton-García J, Robin-Marieton E, Jaksic O, Kohn M, Marchesi F, Marchetti M, El-Ashwah S, Demirkan F, Valković T, Fernández N, Tisi MC, Stojanoski Z, Seval GC, Ilhan O, Prezioso L, Merelli M, López-García A, Ledoux MP, Kulasekararaj A, González-López TJ, Gomes da Silva M, Emarah Z, Duarte RF, Cattaneo C, Blennow O, Bilgin YM, Bergantim R, Batinić J, Cordoba R, Essame J, Nordlander A, Nunes Rodrigues R, Sacchi MV, Zompi S, Busca A, Corradini P, Hoenigl M, Klimko N, Koehler P, Pagliuca A, Passamonti F, Duléry R, Cornely OA, Besson C, Pagano L (2022). COVID-19 and hairy-cell leukemia: an EPICOVIDEHA survey. Blood Adv. Jul 12;6(13):3870-3874. doi: 10.1182/bloodadvances.2022007357. PMID: 35500220
  • Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, Ortiz AB, Salazar A, Chercoles AG, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A, Holten AR, Mayer A, Bandera A, Cherubini A, Protti A, Aghemo A, Gerussi A, Ramirez A, Braun A, Nebel A, Barreira A, Lleo A, Teles A, Kildal AB, Biondi A, Caballero-Garralda A, Ganna A, Gori A, Glück A, Lind A, Tanck A, Hinney A, Nolla AC, Fracanzani AL, Peschuck A, Cavallero A, Dyrhol-Riise AM, Ruello A, Julià A, Muscatello A, Pesenti A, Voza A, Rando-Segura A, Solier A, Schmidt A, Cortes B, Mateos B, Nafria-Jimenez B, Schaefer B, Jensen B, Bellinghausen C, Maj C, Ferrando C, Horra C, Quereda C, Skurk C, Thibeault C, Scollo C, Herr C, Spinner CD, Gassner C, Lange C, Hu C, Paccapelo C, Lehmann C, Angelini C, Cappadona C, Azuure C; COVICAT study group, Aachen Study (COVAS), Bianco C, Cea C, Sancho C, Hoff DAL, Galimberti D, Prati D, Haschka D, Jiménez D, Pestaña D, Toapanta D, Muñiz-Diaz E, Azzolini E, Sandoval E, Binatti E, Scarpini E, Helbig ET, Casalone E, Urrechaga E, Paraboschi EM, Pontali E, Reverter E, Calderón EJ, Navas E, Solligård E, Contro E, Arana-Arri E, Aziz F, Garcia F, Sánchez FG, Ceriotti F, Martinelli-Boneschi F, Peyvandi F, Kurth F, Blasi F, Malvestiti F, Medrano FJ, Mesonero F, Rodriguez-Frias F, Hanses F, Müller F, Hemmrich-Stanisak G, Bellani G, Grasselli G, Pezzoli G, Costantino G, Albano G, Cardamone G, Bellelli G, Citerio G, Foti G, Lamorte G, Matullo G, Baselli G, Kurihara H, Neb H, My I, Kurth I, Hernández I, Pink I, Rojas I, Galván-Femenia I, Holter JC, Afset JE, Heyckendorf J, Kässens J, Damås JK, Rybniker J, Altmüller J, Ampuero J, Martín J, Erdmann J, Banales JM, Badia JR, Dopazo J, Schneider J, Bergan J, Barretina J, Walter J, Quero JH, Goikoetxea J, Delgado J, Guerrero JM, Fazaal J, Kraft J, Schröder J, Risnes K, Banasik K, Müller KE, Gaede KI, Garcia-Etxebarria K, Tonby K, Heggelund L, Izquierdo-Sanchez L, Bettini LR, Sumoy L, Sander LE, Lippert LJ, Terranova L, Nkambule L, Knopp L, Gustad LT, Garbarino L, Santoro L, Téllez L, Roade L, Ostadreza M, Intxausti M, Kogevinas M, Riveiro-Barciela M, Berger MM, Schaefer M, Niemi MEK, Gutiérrez-Stampa MA, Carrabba M, Figuera Basso ME, Valsecchi MG, Hernandez-Tejero M, Vehreschild MJGT, Manunta M, Acosta-Herrera M, D'Angiò M, Baldini M, Cazzaniga M, Grimsrud MM, Cornberg M, Nöthen MM, Marquié M, Castoldi M, Cordioli M, Cecconi M, D'Amato M, Augustin M, Tomasi M, Boada M, Dreher M, Seilmaier MJ, Joannidis M, Wittig M, Mazzocco M, Ciccarelli M, Rodríguez-Gandía M, Bocciolone M, Miozzo M, Ayo NI, Blay N, Chueca N, Montano N, Braun N, Ludwig N, Marx N, Martínez N; Norwegian SARS-CoV-2 Study group, Cornely OA, Witzke O, Palmieri O; Pa Study Group, Faverio P, Preatoni P, Bonfanti P, Omodei P, Tentorio P, Castro P, Rodrigues PM, España PP, Hoffmann P, Rosenstiel P, Schommers P, Suwalski P, Pablo R, Ferrer R, Bals R, Gualtierotti R, Gallego-Durán R, Nieto R, Carpani R, Morilla R, Badalamenti S, Haider S, Ciesek S, May S, Bombace S, Marsal S, Pigazzini S, Klein S, Pelusi S, Wilfling S, Bosari S, Volland S, Brunak S, Raychaudhuri S, Schreiber S, Heilmann-Heimbach S, Aliberti S, Ripke S, Dudman S, Wesse T, Zheng T; STORM Study group, The Humanitas Task Force, The Humanitas Gavazzeni Task Force, Bahmer T, Eggermann T, Illig T, Brenner T, Pumarola T, Feldt T, Folseraas T, Cejudo TG, Landmesser U, Protzer U, Hehr U, Rimoldi V, Monzani V, Skogen V, Keitel V, Kopfnagel V, Friaza V, Andrade V, Moreno V, Albrecht W, Peter W, Poller W, Farre X, Yi X, Wang X, Khodamoradi Y, Karadeniz Z, Latiano A, Goerg S, Bacher P, Koehler P, Tran F, Zoller H, Schulte EC, Heidecker B, Ludwig KU, Fernández J, Romero-Gómez M, Albillos A, Invernizzi P, Buti M, Duga S, Bujanda L, Hov JR, Lenz TL, Asselta R, Cid R, Valenti L, Karlsen TH, Cáceres M, Franke A (2022). Detailed stratified GWAS analysis for severe COVID-19 in four European populations. Hum Mol Genet. Jul 15:ddac158. doi: 10.1093/hmg/ddac158. Epub ahead of print. PMID: 35848942.
  • Zhang J, Zhang Y, Wu D, Cao G, Hamed K, Desai A, Aram JA, Guo X, Fayyad R, Cornely OA (2022). Plain language summary: use of isavuconazole in Chinese patients with an invasive fungal disease. Future Microbiol. Oct;17:1203-1206. doi: 10.2217/fmb-2022-0093. Epub 2022 Aug 2. PMID: 35916057.
  • Hoenigl M, Sprute R, Arastehfar A, Perfect JR, Lass-Flörl C, Bellmann R, Prattes J, Thompson GR 3rd, Wiederhold NP, Al Obaidi MM, Willinger B, Arendrup MC, Koehler P, Oliverio M, Egger M, Schwartz IS, Cornely OA, Pappas PG, Krause R (2022). Invasive candidiasis: investigational drugs in the clinical development pipeline and mechanisms of action. Expert Opin Investig Drugs. Aug;31(8):795-812. doi: 10.1080/13543784.2022.2086120. Epub Jun 15. PMID: 35657026; PMCID: PMC9339492.
  • Grothe J, Sprute R, Cornely OA (2022). Comment on: Nephrotoxicity of continuous amphotericin B in critically ill patients with abdominal sepsis: a retrospective analysis with propensity score matching. J Antimicrob Chemother. Jul 28;77(8):2308-2309. doi: 10.1093/jac/dkac098. PMID: 35325191; PMCID: PMC9333405.
  • Sal E, Stemler J, Salmanton-García J, Falces-Romero I, Kredics L, Meyer E, Würstl B, Lass-Flörl C, Racil Z, Klimko N, Cesaro S, Kindo AJ, Wisplinghoff H, Koehler P, Cornely OA, Seidel D (2022). Invasive Trichoderma spp. infections: clinical presentation and outcome of cases from the literature and the FungiScope® registry. J Antimicrob Chemother. Sep 30;77(10):2850-2858. doi: 10.1093/jac/dkac235. PMID: 35929089; PMCID: PMC9525085.
  • Mellinghoff SC, Bruns C, Al-Monajjed R, Cornely FB, Grosheva M, Hampl JA, Jakob C, Koehler FC, Lechmann M, Maged B, Otto-Lambertz C, Rongisch R, Rutz J, Salmanton-Garcia J, Schlachtenberger G, Stemler J, Vehreschild J, Wülfing S, Cornely OA, Liss BJ (2022). Harmonized procedure coding system for surgical procedures and analysis of surgical site infections (SSI) of five European countries. BMC Med Res Methodol. Aug 12;22(1):225. doi: 10.1186/s12874-022-01702-w. PMID: 35962320; PMCID: PMC9374282.
  • Saggau C, Martini GR, Rosati E, Meise S, Messner B, Kamps AK, Bekel N, Gigla J, Rose R, Voß M, Geisen UM, Reid HM, Sümbül M, Tran F, Berner DK, Khodamoradi Y, Vehreschild MJGT, Cornely OA, Koehler P, Krumbholz A, Fickenscher H, Kreuzer O, Schreiber C, Franke A, Schreiber S, Hoyer B, Scheffold A, Bacher P (2022). The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination. Immunity. Oct 11;55(10):1924-1939.e5. doi: 10.1016/j.immuni.2022.08.003. Epub Aug 12. PMID: 35985324; PMCID: PMC9372089.
  • Grothe JH, Cornely OA, Salmanton-García J; VACCELERATE consortium (2022). Monkeypox diagnostic and treatment capacity at epidemic onset: A VACCELERATE online survey. J Infect Public Health. Aug 27;15(10):1043-1046. doi: 10.1016/j.jiph.2022.08.008. Epub ahead of print. PMID: 36049256; PMCID: PMC9420010.

 

Mauro Corrado

  • Corrado M, Pearce EL (2022). Targeting memory T cell metabolism to improve immunity. J Clin Invest. 2022 Jan 4;132(1):e148546. doi: 10.1172/JCI148546. PMID: 34981777; PMCID: PMC8718135.
  • Corrado M, Diana M, Nicholas J(2022). Metabolites: fuelling the immune response. Clin Exp Immunol. 2022 Jun 11;208(2):129-131. doi: 10.1093/cei/uxac053. PMID: 35576509; PMCID: PMC9188342.

Constantinos Demetriades

  • Fernandes SA, Demetriades C (2022). The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging. Front Aging. 2021 Aug 27;2:707372. doi: 10.3389/fragi.2021.707372. PMID: 35822019; PMCID: PMC9261424.
  • Gollwitzer P, Grützmacher N, Wilhelm S, Kümmel D, Demetriades C (2022). A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids. Nat Cell Biol. 2022 Sep;24(9):1394-1406. doi: 10.1038/s41556-022-00976-y. Epub 2022 Sep 12. PMID: 36097072; PMCID: PMC9481461.

Martin Denzel

Martin Denzel

  • Allmeroth K, Hartman MD, Purrio M, Mesaros A, Denzel MS (2022). Hexosamine pathway activation improves memory but does not extend lifespan in mice. Aging Cell. 2022 Oct;21(10):e13711. doi: 10.1111/acel.13711. Epub 2022 Sep 19. PMID: 36124412; PMCID: PMC9577955.

Sabine Eming

  • Dichtl S, Sanin DE, Koss CK, Willenborg S, Petzold A, Tanzer MC, Dahl A, Kabat AM, Lindenthal L, Zeitler L, Satzinger S, Strasser A, Mann M, Roers A, Eming SA, El Kasmi KC, Pearce EJ, Murray PJ (2022). Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF. Life Sci Alliance.2022 Jan 13;5(4):e202101315. doi: 10.26508/lsa.202101315. PMID: 35027468; PMCID: PMC8761491.
  • Sanin DE, Ge Y, Marinkovic E, Kabat AM, Castoldi A, Caputa G, Grzes KM, Curtis JD, Thompson EA, Willenborg S, Dichtl S, Reinhardt S, Dahl A, Pearce EL, Eming SA, Gerbaulet A, Roers A, Murray PJ, Pearce EJ (2022). A common framework of monocyte-derived macrophage activation. Sci Immunol. 2022 Apr 15;7(70):eabl7482. doi: 10.1126/sciimmunol.abl7482. Epub 2022 Apr 15. PMID: 35427180. 
  • Willenborg S, Roscito JG, Gerbaulet A, Roers A, Dahl A, Eming SA, Reinhardt S (2022). Isolation of macrophages from mouse skin wounds for single-cell RNA sequencing. STAR Protoc. 2022 Apr 19;3(2):101337. doi: 10.1016/j.xpro.2022.101337. PMID: 35496783; PMCID: PMC9046999.
  • Willenborg S, Injarabian L, Eming SA (2022). Role of Macrophages in Wound Healing. Cold Spring Harb Perspect Biol. 2022 Aug 30:a041216. doi: 10.1101/cshperspect.a041216. Epub ahead of print. PMID: 36041784.

Lukas P. Frenzel

  • Izquierdo E, Vorholt D, Blakemore SJ, Sackey B, Nolte JL, Barbarino V, Schmitz JH, Nickel N, Bachurski D, Lobastova L, Nikolic M, Michalik M, Brinker R, Merkel O, Franitza M, Georgomanolis T, Neuhaus R, Koch MRK, Nasada N, Knittel G, Chapuy B, Ludwig N, Meese E, Frenzel LP, Reinhardt HC, Peifer M, Rebollido-Rios R, Bruns H, Krüger M, Hallek M, Pallasch CP (2022).Extracellular vesicles and PDL1 suppress macrophages inducing therapy resistance in TP53-deficient B-cell malignancies. Blood. 2022 Mar 28:blood.2021014007. doi: 10.1182/blood.2021014007. Epub ahead of print. PMID: 35344582.
  • Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling CD, Nieper P, Feldmann T, Merkel O, Lorsy E, da Palma Guerreiro A, von Jan J, Kisis I, Wasserburger E, Claasen J, Faitschuk-Meyer E, Altmüller J, Nürnberg P, Yang TP, Lienhard M, Herwig R, Kreuzer KA, Pallasch CP, Buettner R, Schäfer SC, Hartley J, Abken H, Peifer M, Kashkar H, Knittel G, Eichhorst B, Ullrich RT, Herling M, Reinhardt HC, Hallek M, Schweiger MR, Frenzel LP (2022). Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies. Blood. 2022 Jun 15:blood.2021014304. doi: 10.1182/blood.2021014304. Epub ahead of print. PMID: 35704690.

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Ana J. Garcia-Saez

  • Jenner A, Peña-Blanco A, Salvador-Gallego R, Ugarte-Uribe B, Zollo C, Ganief T, Bierlmeier J, Mund M, Lee JE, Ries J, Schwarzer D, Macek B, Garcia-Saez AJ (2022). DRP1 interacts directly with BAX to induce its activation and apoptosis. EMBO J. 2022 Jan 13:e108587. doi: 10.15252/embj.2021108587. Epub ahead of print. PMID: 35023587. 
  • Danial JSH, Quintana Y, Ros U, Shalaby R, Margheritis EG, Chumpen Ramirez S, Ungermann C, Garcia-Saez AJ, Cosentino K (2022). Systematic Assessment of the Accuracy of Subunit Counting in Biomolecular Complexes Using Automated Single-Molecule Brightness Analysis. J Phys Chem Lett. 2022 Jan 27;13(3):822-829. doi: 10.1021/acs.jpclett.1c03835. Epub 2022 Jan 19. PMID: 35044771; PMCID: PMC8802318.
  • Cosentino K, Hertlein V, Jenner A, Dellmann T, Gojkovic M, Peña-Blanco A, Dadsena S, Wajngarten N, Danial JSH, Thevathasan JV, Mund M, Ries J, Garcia-Saez AJ (2022). The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation. Mol Cell. 2022 Mar 3;82(5):933-949.e9. doi: 10.1016/j.molcel.2022.01.008. Epub 2022 Feb 3. PMID: 35120587; PMCID: PMC8901441.
  • Guéguinou M, Ibrahim S, Bourgeais J, Robert A, Pathak T, Zhang X, Crottès D, Dupuy J, Ternant D, Monbet V, Guibon R, Flores-Romero H, Lefèvre A, Lerondel S, Le Pape A, Dumas JF, Frank PG, Girault A, Chautard R, Guéraud F, García-Sáez AJ, Ouaissi M, Emond P, Sire O, Hérault O, Fromont-Hankard G, Vandier C, Tougeron D, Trebak M, Raoul W, Lecomte T (2022). Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer. Cell Mol Life Sci. 2022 May 8;79(6):284. doi: 10.1007/s00018-022-04311-4. PMID: 35526196.
  • Flores-Romero H, García-Sáez AJ. MERLIN: A BRET-Based Proximity Biosensor for Studying Mitochondria-ER Contact Sites. Methods Mol Biol. 2022;2525:197-205. doi: 10.1007/978-1-0716-2473-9_14. PMID: 35836069.

Annika Graband

  • Baess SC, Burkhart AK, Cappello S, Graband A, Seré K, Zenke M, Niemann C, Iden S (2022). Lrig1- and Wnt-dependent niches dictate segregation of resident immune cells and melanocytes in murine tail epidermis. Development. Jul 15;149(14):dev200154. doi: 10.1242/dev.200154. Epub 2022 Jul 14. PMID: 35815643; PMCID: PMC9382897.

Michael Hallek

  • Garcia Borrega J, Heger JM, Koehler P, Holtick U, Hallek M, Scheid C, Böll B, Shimabukuro-Vornhagen A, Kochanek M, Eichenauer DA (2022). Allogeneic stem cell transplant recipients admitted to the intensive care unit during the peri-transplant period have unfavorable outcomes-results of a retrospective analysis from a German university hospital. Ann Hematol. 2022 Feb;101(2):389-395. doi: 10.1007/s00277-021-04698-3. Epub 2021 Oct 20. PMID: 34668981; PMCID: PMC8742807.
  • Jacob AS, Kaul H, Fuchs M, Gillessen S, Kreissl S, Pluetschow A, Momotow J, Schaub V, Huettmann A, Haenel M, Zimmermann A, Dierlamm J, Meissner J, Mathas S, Martin S, Engert A, Hallek M, Borchmann P, Lehmann C (2022). Impact of the first COVID-19 lockdown in Germany on the rate of acute infections during intensive chemotherapy for Hodgkin lymphoma. Infection. 2022 Feb 19:1–8. doi: 10.1007/s15010-022-01765-3. Epub ahead of print. PMID: 35182355; PMCID: PMC8857743. 
  • Hieber ML, Sprute R, Eichenauer DA, Hallek M, Jachimowicz RD (2022). Hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination. Infection. 2022 Feb 26:1–6. doi: 10.1007/s15010-022-01786-y. Epub ahead of print. PMID: 35218512; PMCID: PMC8881936.
  • Braun T, Stachelscheid J, Bley N, Oberbeck S, Otte M, Müller TA, Wahnschaffe L, Glaß M, Ommer K, Franitza M, Gathof B, Altmüller J, Hallek M, Auguin D, Hüttelmaier S, Schrader A, Herling M (2022). Non-canonical function of AGO2 augments T-cell receptor signaling in T-cell prolymphocytic leukemia. Cancer Res. 2022 Mar 8:canres.1908.2021. doi: 10.1158/0008-5472.CAN-21-1908. Epub ahead of print. PMID: 35259248. 
  • Izquierdo E, Vorholt D, Blakemore SJ, Sackey B, Nolte JL, Barbarino V, Schmitz JH, Nickel N, Bachurski D, Lobastova L, Nikolic M, Michalik M, Brinker R, Merkel O, Franitza M, Georgomanolis T, Neuhaus R, Koch MRK, Nasada N, Knittel G, Chapuy B, Ludwig N, Meese E, Frenzel LP, Reinhardt HC, Peifer M, Rebollido-Rios R, Bruns H,Krüger M, Hallek M,Pallasch CP (2022).Extracellular vesicles and PDL1 suppress macrophages inducing therapy resistance in TP53-deficient B-cell malignancies. Blood. 2022 Mar 28:blood.2021014007. doi: 10.1182/blood.2021014007. Epub ahead of print. PMID: 35344582. 
  • Bonifacius A, Tischer-Zimmermann S, Santamorena MM, Mausberg P, Schenk J, Koch S, Barnstorf-Brandes J, Gödecke N, Martens J, Goudeva L, Verboom M, Wittig J, Maecker-Kolhoff B, Baurmann H, Clark C, Brauns O, Simon M, Lang P, Cornely OA, Hallek M, Blasczyk R, Seiferling D, Köhler P, Eiz-Vesper B. Rapid Manufacturing of Highly Cytotoxic Clinical-Grade SARS-CoV-2-specific T Cell Products Covering SARS-CoV-2 and Its Variants for Adoptive T Cell Therapy.Front Bioeng Biotechnol. 2022 Apr 4;10:867042. doi: 10.3389/fbioe.2022.867042. PMID: 35480981; PMCID: PMC9036989. 
  • Rusyn L, Reinartz S, Nikiforov A, Mikhael N, Vom Stein A, Kohlhas V, Bloehdorn J, Stilgenbauer S, Lohneis P, Buettner R, Robrecht S, Fischer K, Pallasch C, Hallek M, Nguyen PH, Seeger-Nukpezah T (2022).The scaffold protein NEDD9 is necessary for leukemia-cell migration and disease progression in a mouse model of chronic lymphocytic leukemia. Leukemia. 2022 Jul;36(7):1794-1805. doi: 10.1038/s41375-022-01586-1. Epub 2022 May 6. PMID: 35523865; PMCID: PMC9252910. 
  • Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling CD, Nieper P, Feldmann T, Merkel O, Lorsy E, da Palma Guerreiro A, von Jan J, Kisis I, Wasserburger E, Claasen J, Faitschuk-Meyer E, Altmüller J, Nürnberg P, Yang TP, Lienhard M, Herwig R, Kreuzer KA, Pallasch CP, Buettner R, Schäfer SC, Hartley J, Abken H, Peifer M, Kashkar H, Knittel G, Eichhorst B, Ullrich RT, Herling M, Reinhardt HC, Hallek M,Schweiger MR, Frenzel LP (2022). Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies. Blood. 2022 Jun 15:blood.2021014304. doi: 10.1182/blood.2021014304. Epub ahead of print. PMID: 35704690.
  • Theobald SJ, Simonis A, Mudler JM, Göbel U, Acton R, Kohlhas V, Albert MC, Hellmann AM, Malin JJ, Winter S, Hallek M, Walczak H, Nguyen PH, Koch M, Rybniker J (2022). Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS-CoV-2 mRNA vaccination. EMBO Mol Med. Jul 4:e15888. doi: 10.15252/emmm.202215888. Online ahead of print PMID: 35785445.
  • Langerbeins P, Hallek M (2022). COVID-19 in patients with hematologic malignancy. Blood. Jul 21;140(3):236-252. doi: 10.1182/blood.2021012251. PMID: 35544585; PMCID: PMC9098396.
  • Knisbacher BA, Lin Z, Hahn CK, Nadeu F, Duran-Ferrer M, Stevenson KE, Tausch E, Delgado J, Barbera-Mourelle A, Taylor-Weiner A, Bousquets-Muñoz P, Diaz-Navarro A, Dunford A, Anand S, Kretzmer H, Gutierrez-Abril J, López-Tamargo S, Fernandes SM, Sun C, Sivina M, Rassenti LZ, Schneider C, Li S, Parida L, Meissner A, Aguet F, Burger JA, Wiestner A, Kipps TJ, Brown JR, Hallek M, Stewart C, Neuberg DS, Martín-Subero JI, Puente XS, Stilgenbauer S, Wu CJ, Campo E, Getz G (2022). Molecular map of chronic lymphocytic leukemia and its impact on outcome. Nat Genet. Aug 4. doi: 10.1038/s41588-022-01140-w. Epub ahead of print. PMID: 35927489.
  • Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P (2022). Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease. Transplant Cell Ther. Jul 31:S2666-6367(22)01514-7. doi: 10.1016/j.jtct.2022.07.027. Epub ahead of print. PMID: 35921986.
  • Tresckow J, Cramer P, Robrecht S, Langerbeins P, Fink AM, Al-Sawaf O, Fürstenau M, Illmer T, Klaproth H, Tausch E, Ritgen M, Fischer K, Wendtner CM, Kreuzer KA, Stilgenbauer S, Böttcher S, Eichhorst BF, Hallek M (2022). Sequential treatment with bendamustine, obinutuzumab (GA101) and Ibrutinib in chronic lymphocytic leukemia (CLL): final results of the CLL2-BIG trial. Leukemia. 2022 Aug;36(8):2125-2128. doi: 10.1038/s41375-022-01629-7. Epub Jun 25. PMID: 35752657; PMCID: PMC9343250.

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Marco Herling

  • Patil P, Toprak UH, Seufert J, Braun T, Bernhart SH, Wiehle L, Müller A, Schlesner M, Herling M, Lichter P, Stilgenbauer S, Siebert R, Zapatka M (2022). Exploration of whole genome and transcriptome sequencing data lacks evidence for oncogenic viral elements to drive the pathogenesis of T-cell prolymphocytic leukemia. Leuk Lymphoma. 2022 Sep 9:1-4. doi: 10.1080/10428194.2022.2116933. Epub ahead of print. PMID: 36083597.
  • Mikhaylenko N, Wahnschaffe L, Herling M, Roeder I, Seifert M (2022). Computational gene expression analysis reveals distinct molecular subgroups of T-cell prolymphocytic leukemia. PLoS One. 2022 Sep 21;17(9):e0274463. doi: 10.1371/journal.pone.0274463. PMID: 36129940; PMCID: PMC9491575.
  • Herling M, Jarjour W, Mishra A, Brammer JE (2022). Editorial: Pathogenesis, treatment, and future directions for rare T-cell leukemias. Front Oncol. 2022 Sep 7;12:991527. doi: 10.3389/fonc.2022.991527. PMID: 36158669; PMCID: PMC9490408.

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Robert Hänsel-Hertsch

  • Hudecova I, Smith CG, Hänsel-Hertsch R, Chilamakuri CS, Morris JA, Vijayaraghavan A, Heider K, Chandrananda D, Cooper WN, Gale D, Garcia-Corbacho J, Pacey S, Baird RD, Rosenfeld N, Mouliere F (2022). Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA. Genome Res. 2022 Feb;32(2):215-227. doi: 10.1101/gr.275691.121. Epub 2021 Dec 20. PMID: 34930798; PMCID: PMC8805718.

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Jan Hoeijmakers

  • Oudmaijer CAJ, Minnee RC, Pol RA, van den Boogaard WMC, Komninos DSJ, van de Wetering J, van Heugten MH, Hoorn EJ, Sanders JSF, Hoeijmakers JHJ, Vermeij WP, IJzermans JNM (2022). Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trial. Trials. 2022 Jan 6;23(1):18. doi: 10.1186/s13063-021-05950-x. PMID: 34991694; PMCID: PMC8733810.
  • Vougioukalaki M, Demmers J, Vermeij WP, Baar M, Bruens S, Magaraki A, Kuijk E, Jager M, Merzouk S, Brandt RMC, Kouwenberg J, van Boxtel R, Cuppen E, Pothof J, Hoeijmakers JHJ (2022). Different responses to DNA damage determine ageing differences between organs. Aging Cell. 2022 Apr;21(4):e13562. doi: 10.1111/acel.13562. Epub 2022 Mar 4. PMID: 35246937; PMCID: PMC9009128.
  • Kajitani GS, Quayle C, Garcia CCM, Fotoran WL, Dos Santos JFR, van der Horst GTJ,Hoeijmakers JHJ, Menck CFM (2022).Photorepair of Either CPD or 6-4PP DNA Lesions in Basal Keratinocytes Attenuates Ultraviolet-Induced Skin Effects in Nucleotide Excision Repair Deficient Mice. Front Immunol. 2022 Mar 29;13:800606. doi: 10.3389/fimmu.2022.800606. PMID: 35422806; PMCID: PMC9004445.
  • He Y, van Mever M, Yang W, Huang L, Ramautar R, Rijksen Y, Vermeij WP, Hoeijmakers JHJ, Harms AC, Lindenburg PW, Hankemeier T (2022). A Sample Preparation Method for the Simultaneous Profiling of Signaling Lipids and Polar Metabolites in Small Quantities of Muscle Tissues from a Mouse Model for Sarcopenia. Metabolites. Aug 12;12(8):742. doi: 10.3390/metabo12080742. PMID: 36005613; PMCID: PMC9413361.

Tamas Horvath

  • Ralevski A, Apelt F, Olas JJ, Mueller-Roeber B, Rugarli EI, Kragler F, Horvath TL (2022). Plant mitochondrial FMT and its mammalian homolog CLUH controls development and behavior in Arabidopsis and locomotion in mice. Cell Mol Life Sci. 2022 Jun 2;79(6):334. doi: 10.1007/s00018-022-04382-3. PMID: 35652974.

Thorsten Hoppe    

  • Segref A., Vakkayil K.L., Padvitski T., Li Q., Kroef V., Lormann J., Körner L., Finger F., Hoppe T (2022). Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling. Nat Commun. 13, 5874.
  • Ravanelli S., Li Q., Annibal A., Trifunovic A., Antebi A., Hoppe T (2022). Reprograming of proteaso-mal degradation by branched chain amino acid metabolism. Aging Cell: e13725.
  • Balaji V., Müller L., Lorenz R., Kevei E., Zhang W.H., Santiago U., Gebauer J., Llamas E., Vilchez E., Camacho C.J., Pokrzywa W., Hoppe T (2022). A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing. Mol Cell. 82, 3239-54.
  • Das A., Thapa P., Santiago U., Shanmugam N., Banasiak K., Dabrowska K., Nolte H., Szulc N.A., Gathungu R.M., Cysewski D., Krüger M., Dadlez M., Nowotny M., Camacho C.J., Hoppe T., Pokrzywa W (2022). A heterotypic assembly mechanism regulates CHIP E3 ligase activity. EMBO J. 41: e109566.
  • Vakkayil K.L. and Hoppe T. (2022). Temperature-Dependent Regulation of Proteostasis and Longevity. Front. Aging 3: 853588.
  • Das A, Thapa P, Santiago U, Shanmugam N, Banasiak K, Dąbrowska K, Nolte H, Szulc NA, Gathungu RM, Cysewski D, Krüger M, Dadlez M, Nowotny M, Camacho CJ, Hoppe T, Pokrzywa W (2022). A heterotypic assembly mechanism regulates CHIP E3 ligase activity. EMBO J. 2022 Aug 1;41(15):e109566. doi: 10.15252/embj.2021109566. Epub  Jun 28. PMID: 35762422; PMCID: PMC9340540.
  • Balaji V, Müller L, Lorenz R, Kevei É, Zhang WH, Santiago U, Gebauer J, Llamas E, Vilchez D, Camacho CJ, Pokrzywa W, Hoppe T (2022). A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing. Mol Cell. 2022 Sep 1;82(17):3239-3254.e11. doi: 10.1016/j.molcel.2022.08.003. Epub 2022 Aug 25. PMID: 36027913.
  • Ravanelli S, Li Q, Annibal A, Trifunovic A, Antebi A, Hoppe T (2022). Reprograming of proteasomal degradation by branched chain amino acid metabolism. Aging Cell. 2022 Sep 27:e13725. doi: 10.1111/acel.13725. Epub ahead of print. PMID: 36168305.

Pitter Huesgen

  • Oberleitner L, Perrar A, Macorano L, Huesgen PF, Nowack ECM (2022). A bipartite chromatophore transit peptide and N-terminal protein processing in the Paulinella chromatophore. Plant Physiol. 2022 Jan 19:kiac012. doi: 10.1093/plphys/kiac012. Epub ahead of print. PMID: 35043947. 
  • Huebbers JW, Büttgen K, Leissing F, Mantz M, Pauly M, Huesgen PF, Panstruga R (2022). An advanced method for the release, enrichment and purification of high-quality Arabidopsis thaliana rosette leaf trichomes enables profound insights into the trichome proteome. Plant Methods. 2022 Jan 28;18(1):12. doi: 10.1186/s13007-021-00836-0. PMID: 35086542; PMCID: PMC8796501. 
  • Demir F, Huesgen PF (2022). A User Guide to Validation, Annotation, and Evaluation of N-Terminome Datasets with MANTI. Methods Mol Biol. 2022;2447:271-283. doi: 10.1007/978-1-0716-2079-3_22. PMID: 35583789.
  • Demir F, Kuppusamy M, Perrar A, Huesgen PF (2022). Profiling Sequence Specificity of Proteolytic Activities Using Proteome-Derived Peptide Libraries. Methods Mol Biol. 2022;2447:159-174. doi: 10.1007/978-1-0716-2079-3_13. PMID: 35583780.
  • Demir F, Perrar A, Mantz M, Huesgen PF (2022). Sensitive Plant N-Terminome Profiling with HUNTER. Methods Mol Biol. 2022;2447:139-158. doi: 10.1007/978-1-0716-2079-3_12. PMID: 35583779.

Ron Jachimowicz

  • Jachimowicz RD, Klapper W, Glehr G, Müller H, Haverkamp H, Thorns C, Hansmann ML, Möller P, Stein H, Rehberg T, von Tresckow B, Reinhardt HC, Borchmann P, Chan FC, Spang R, Scott DW, Engert A, Steidl C, Altenbuchinger M, Rosenwald A (2022). Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP. Leukemia. 2021 Dec;35(12):3589-3593. doi: 10.1038/s41375-021-01314-1. Epub 2021 Jun 10. PMID: 34112956; PMCID: PMC8632672.
  • Hieber ML, Sprute R, Eichenauer DA, Hallek M, Jachimowicz RD (2022). Hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination. Infection. 2022 Feb 26:1–6. doi: 10.1007/s15010-022-01786-y. Epub ahead of print. PMID: 35218512; PMCID: PMC8881936.

Frank Jessen

  • Wang X, Bi Q, Lu J, Chan P, Hu X, Su L, Jessen F, Lin H, Han C, Shu N, Liu H, Han Y (2022). Difference in Amyloid Load Between Single Memory Domain and Multidomain Subjective Cognitive Decline: A Study from the SILCODE. J Alzheimers Dis. 2022;85(4):1573-1582. doi: 10.3233/JAD-215373. PMID: 34958039.
  • Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Chételat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerström M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fröhlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, Gómez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lleó A, Löwenmark M, Madsen K, Maier W, Marcusson J, Marquié M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendonça A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodríguez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, Rüther E, Ruiz A, Sabri O, Sakhardande J, Sánchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schröder J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H (2022). Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. JAMA Neurol. 2022 Jan 31. doi: 10.1001/jamaneurol.2021.5216. Epub ahead of print. PMID: 35099509.
  • Rostamzadeh A, Kahlert A, Kalthegener F, Jessen F (2022). Psychotherapeutic interventions in individuals at risk for Alzheimer's dementia: a systematic review. Alzheimers Res Ther. 2022 Jan 31;14(1):18. doi: 10.1186/s13195-021-00956-8. Erratum in: Alzheimers Res Ther. 2022 Mar 22;14(1):44. PMID: 35101105; PMCID: PMC8802419.
  • Martino Adami PV, Orellana A, García P, Kleineidam L, Alarcón-Martín E, Montrreal L, Aguilera N, Espinosa A, Abdelnour C, Rosende-Roca M, Tartari JP, Vargas L, Mauleón A, Esteban-De Antonio E, López-Cuevas R, Dalmasso MC, Martin RC, Parveen K, Andrade Fuentes VM, Amin N, Ahmad S, Ikram MA, Lewczuk P, Kornhuber J, Peters O, Frölich L, Rüther E, Wiltfang J, Tarraga L, Boada M, Maier W, de Rojas I, Cano A, Sanabria A, Alegret M, Hernández I, Marquié M, Valero S, van Duijn CM, Wagner M, Jessen F, Schneider A, Sáez Goñi ME, Pérez AG, Ruiz A, Ramírez A (2022). Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer's type. Brain. 2022 Jan 28:awac024. doi: 10.1093/brain/awac024. Epub ahead of print. PMID: 35088840. 
  • Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W Jr, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, Tosto G, Traykov L, Tremolizzo L, Tybjærg-Hansen A, Uitterlinden A, Ullgren A, Ulstein I, Valero S, Valladares O, Broeckhoven CV, Vance J, Vardarajan BN, van der Lugt A, Dongen JV, van Rooij J, van Swieten J, Vandenberghe R, Verhey F, Vidal JS, Vogelgsang J, Vyhnalek M, Wagner M, Wallon D, Wang LS, Wang R, Weinhold L, Wiltfang J, Windle G, Woods B, Yannakoulia M, Zare H, Zhao Y, Zhang X, Zhu C, Zulaica M; EADB; GR@ACE; DEGESCO; EADI; GERAD; Demgene; FinnGen; ADGC; CHARGE, Farrer LA, Psaty BM, Ghanbari M, Raj T, Sachdev P, Mather K, Jessen F, Ikram MA, de Mendonça A, Hort J, Tsolaki M, Pericak-Vance MA, Amouyel P, Williams J, Frikke-Schmidt R, Clarimon J, Deleuze JF, Rossi G, Seshadri S, Andreassen OA, Ingelsson M, Hiltunen M, Sleegers K, Schellenberg GD, van Duijn CM, Sims R, van der Flier WM, Ruiz A, Ramirez A, Lambert JC (2022). New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet.2022 Apr;54(4):412-436. doi: 10.1038/s41588-022-01024-z. Epub 2022 Apr 4. PMID: 35379992; PMCID: PMC9005347.
  • Brosseron F, Maass A, Kleineidam L, Ravichandran KA, González PG, McManus RM, Ising C, Santarelli F, Kolbe CC, Häsler LM, Wolfsgruber S, Marquié M, Boada M, Orellana A, de Rojas I, Röske S, Peters O, Cosma NC, Cetindag A, Wang X, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Schott BH, Bürger K, Janowitz D, Dichgans M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Düzel E, Yakupov R, Dobisch L, Metzger CD, Glanz W, Ewers M, Dechent P, Haynes JD, Scheffler K, Roy N, Rostamzadeh A, Teunissen CE, Marchant NL, Spottke A, Jucker M, Latz E, Wagner M, Mengel D, Synofzik M, Jessen F, Ramirez A, Ruiz A, Heneka MT; DELCODE study group (2022). Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron. 2022 Mar 16;110(6):1009-1022.e4. doi: 10.1016/j.neuron.2021.12.016. Epub 2022 Jan 6. PMID: 34995486. 
  • Sheng C, Yang K, He B, Li T, Wang X, Du W, Hu X, Jiang J, Jiang X, Jessen F, Han Y (2022). Cross-Cultural Longitudinal Study on Cognitive Decline (CLoCODE) for Subjective Cognitive Decline in China and Germany: A Protocol for Study Design. J Alzheimers Dis. 2022 Apr 15. doi: 10.3233/JAD-215452. Epub ahead of print. PMID: 35431240.
  • Gerards M, Schild AK, Meiberth D, Rostamzadeh A, Vehreschild JJ, Wingen-Heimann S, Johannis W, Martino Adami P, Onur OA,Ramirez A, Karikari TK, Ashton NJ, Zetterberg H, Blennow K, Maier F, Jessen F (2022). Alzheimer's Disease Plasma Biomarkers Distinguish Clinical Diagnostic Groups in Memory Clinic Patients. Dement Geriatr Cogn Disord. 2022 May 3:1-11. doi: 10.1159/000524390. Epub ahead of print. PMID: 35504263.  
  • Wolfsgruber S, Kleineidam L, Weyrauch AS, Barkhoff M, Röske S, Peters O, Preis L, Gref D, Spruth EJ, Altenstein S, Priller J, Fließbach K, Schneider A, Wiltfang J, Bartels C, Jessen F, Maier F, Düzel E, Metzger C, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Kilimann I, Teipel S, Laske C, Munk MH, Roy N, Spottke A, Ramirez A, Heneka MT, Brosseron F, Wagner M; DELCODE study group (2022). Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease. J Alzheimers Dis. 2022;87(2):545-555. doi: 10.3233/JAD-215416. PMID: 35275535.
  • Le Guen Y, Belloy ME, Grenier-Boley B, de Rojas I, Castillo-Morales A, Jansen I, Nicolas A, Bellenguez C, Dalmasso C, Küçükali F, Eger SJ, Rasmussen KL, Thomassen JQ, Deleuze JF, He Z, Napolioni V, Amouyel P, Jessen F, Kehoe PG, van Duijn C, Tsolaki M, Sánchez-Juan P, Sleegers K, Ingelsson M, Rossi G, Hiltunen M, Sims R, van der Flier WM, Ramirez A, Andreassen OA, Frikke-Schmidt R, Williams J, Ruiz A, Lambert JC, Greicius MD; Members of the EADB, GR@ACE, DEGESCO, DemGene, GERAD, and EADI Groups, Arosio B, Benussi L, Boland A, Borroni B, Caffarra P, Daian D, Daniele A, Debette S, Dufouil C, Düzel E, Galimberti D, Giedraitis V, Grimmer T, Graff C, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Holstege H, Hort J, Jürgen D, Kuulasmaa T, van der Lugt A, Masullo C, Mecocci P, Mehrabian S, de Mendonça A, Moebus S, Nacmias B, Nicolas G, Olaso R, Papenberg G, Parnetti L, Pasquier F, Peters O, Pijnenburg YAL, Popp J, Rainero I, Ramakers I, Riedel-Heller S, Scarmeas N, Scheltens P, Scherbaum N, Schneider A, Seripa D, Soininen H, Solfrizzi V, Spalletta G, Squassina A, van Swieten J, Tegos TJ, Tremolizzo L, Verhey F, Vyhnalek M, Wiltfang J, Boada M, García-González P, Puerta R, Real LM, Álvarez V, Bullido MJ, Clarimon J, García-Alberca JM, Mir P, Moreno F, Pastor P, Piñol-Ripoll G, Molina-Porcel L, Pérez-Tur J, Rodríguez-Rodríguez E, Royo JL, Sánchez-Valle R, Dichgans M, Rujescu D (2022). Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease. JAMA Neurol. 2022 Jul 1;79(7):652-663. doi: 10.1001/jamaneurol.2022.1166. PMID: 35639372; PMCID: PMC9157381
  • Billette OV, Ziegler G, Aruci M, Schütze H, Kizilirmak JM, Richter A, Altenstein S, Bartels C, Brosseron F, Cardenas-Blanco A, Dahmen P, Dechent P, Dobisch L, Fliessbach K, Freiesleben SD, Glanz W, Göerß D, Haynes JD, Heneka MT, Kilimann I, Kimmich O, Kleineidam L, Laske C, Lohse A, Rostamzadeh A, Metzger C, Munk MH, Peters O, Preis L, Priller J, Scheffler K, Schneider A, Spottke A, Spruth EJ, Ramirez A, Röske S, Roy N, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Yakupov R, Zeidman P, Jessen F, Schott BH, Düzel E, Maass A; DELCODE Study Group (2022). Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease. Neurology. Aug 23;99(8):e775-e788. doi: 10.1212/WNL.0000000000200667. Epub Jun 3. PMID: 35995589; PMCID: PMC9484732.
  • Rostamzadeh A, Bohr L, Wagner M, Baethge C, Jessen F (2022). Progression of Subjective Cognitive Decline to MCI or Dementia in Relation to Biomarkers for Alzheimer Disease: A Meta-analysis. Neurology. 2022 Oct 25;99(17):e1866-e1874. doi: 10.1212/WNL.0000000000201072. Epub 2022 Aug 26. PMID: 36028322.
  • Whitfield T, Demnitz-King H, Schlosser M, Barnhofer T, Frison E, Coll-Padros N, Dautricourt S, Requier F, Delarue M, Gonneaud J, Klimecki OM, Lutz A, Paly L, Salmon E, Schild AK, Walker Z, Jessen F, Chételat G, Collette F, Wirth M, Marchant NL; Medit-Ageing Research Group (2022). Effects of a mindfulness-based versus a health self-management intervention on objective cognitive performance in older adults with subjective cognitive decline (SCD): a secondary analysis of the SCD-Well randomized controlled trial. Alzheimers Res Ther. 2022 Sep 6;14(1):125. doi: 10.1186/s13195-022-01057-w. PMID: 36068621; PMCID: PMC9446839.
  • Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, Vromen EM, Wightman DP, Alcolea D, Alegret M, Alvarez I, Amouyel P, Athanasiu L, Bahrami S, Bailly H, Belbin O, Bergh S, Bertram L, Biessels GJ, Blennow K, Blesa R, Boada M, Boland A, Buerger K, Carracedo Á, Cervera-Carles L, Chene G, Claassen JAHR, Debette S, Deleuze JF, de Deyn PP, Diehl-Schmid J, Djurovic S, Dols-Icardo O, Dufouil C, Duron E, Düzel E; EADB consortium, Fladby T, Fortea J, Frölich L, García-González P, Garcia-Martinez M, Giegling I, Goldhardt O, Gobom J, Grimmer T, Haapasalo A, Hampel H, Hanon O, Hausner L, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herukka SK, Holstege H, Jarholm J, Kern S, Knapskog AB, Koivisto AM, Kornhuber J, Kuulasmaa T, Lage C, Laske C, Leinonen V, Lewczuk P, Lleó A, de Munain AL, Lopez-Garcia S, Maier W, Marquié M, Mol MO, Montrreal L, Moreno F, Moreno-Grau S, Nicolas G, Nöthen MM, Orellana A, Pålhaugen L, Papma JM, Pasquier F, Perneczky R, Peters O, Pijnenburg YAL, Popp J, Posthuma D, Pozueta A, Priller J, Puerta R, Quintela I, Ramakers I, Rodriguez-Rodriguez E, Rujescu D, Saltvedt I, Sanchez-Juan P, Scheltens P, Scherbaum N, Schmid M, Schneider A, Selbæk G, Selnes P, Shadrin A, Skoog I, Soininen H, Tárraga L, Teipel S; GR@ACE study group, Tijms B, Tsolaki M, Van Broeckhoven C, Van Dongen J, van Swieten JC, Vandenberghe R, Vidal JS, Visser PJ, Vogelgsang J, Waern M, Wagner M, Wiltfang J, Wittens MMJ, Zetterberg H, Zulaica M, van Duijn CM, Bjerke M, Engelborghs S, Jessen F, Teunissen CE, Pastor P, Hiltunen M, Ingelsson M, Andreassen OA, Clarimón J, Sleegers K, Ruiz A, Ramirez A, Cruchaga C, Lambert JC, van der Flier W (2022). Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathol. 2022 Nov;144(5):821-842. doi: 10.1007/s00401-022-02454-z. Epub 2022 Sep 6. PMID: 36066633; PMCID: PMC9547780.
  • Böttcher A, Zarucha A, Köbe T, Gaubert M, Höppner A, Altenstein S, Bartels C, Buerger K, Dechent P, Dobisch L, Ewers M, Fliessbach K, Freiesleben SD, Frommann I, Haynes JD, Janowitz D, Kilimann I, Kleineidam L, Laske C, Maier F, Metzger C, Munk MHJ, Perneczky R, Peters O, Priller J, Rauchmann BS, Roy N, Scheffler K, Schneider A, Spottke A, Teipel SJ, Wiltfang J, Wolfsgruber S, Yakupov R, Düzel E, Jessen F, Röske S, Wagner M, Kempermann G, Wirth M (2022). Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults. Front Psychol. 2022 Aug 25;13:945709. doi: 10.3389/fpsyg.2022.945709. PMID: 36092026; PMCID: PMC9454948.

Hamid Kashkar

  • Simpson DS, Pang J, Weir A, Kong IY, Fritsch M, Rashidi M, Cooney JP, Davidson KC, Speir M, Djajawi TM, Hughes S, Mackiewicz L, Dayton M, Anderton H, Doerflinger M, Deng Y, Huang AS, Conos SA, Tye H, Chow SH, Rahman A, Norton RS, Naderer T, Nicholson SE, Burgio G, Man SM, Groom JR, Herold MJ, Hawkins ED, Lawlor KE, Strasser A, Silke J, Pellegrini M, Kashkar H, Feltham R, Vince JE (2022). Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway. Immunity. 2022 Mar 8;55(3):423-441.e9. doi: 10.1016/j.immuni.2022.01.003. Epub 2022 Feb 8. PMID: 35139355; PMCID: PMC8822620. 
  • Daoud M, Broxtermann PN, Schorn F, Werthenbach JP, Seeger JM, Schiffmann LM, Brinkmann K, Vucic D, Tüting T, Mauch C, Kulms D, Zigrino P, Kashkar H (2022).XIAP promotes melanoma growth by inducing tumour neutrophil infiltration. EMBO Rep. 2022 Apr 19:e53608. doi: 10.15252/embr.202153608. Epub ahead ofprint. PMID: 35437868.
  • Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling CD, Nieper P, Feldmann T, Merkel O, Lorsy E, da Palma Guerreiro A, von Jan J, Kisis I, Wasserburger E, Claasen J, Faitschuk-Meyer E, Altmüller J, Nürnberg P, Yang TP, Lienhard M, Herwig R, Kreuzer KA, Pallasch CP, Buettner R, Schäfer SC, Hartley J, Abken H, Peifer M, Kashkar H, Knittel G, Eichhorst B, Ullrich RT, Herling M, Reinhardt HC, Hallek M, Schweiger MR, Frenzel LP (2022). Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies. Blood. 2022 Jun 15:blood.2021014304. doi: 10.1182/blood.2021014304. Epub ahead of print. PMID: 35704690.

Natalia Kononenko

  • Sona C, Yeh YT, Patsalos A, Halasz L, Yan X, Kononenko NL, Nagy L, Poy MN (2022). Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes. JCI Insight. 2022 Mar 22;7(6):e153136. doi: 10.1172/jci.insight.153136. PMID: 35133983; PMCID: PMC8986082.

Thomas Krieg

  • Jerjen R, Nikpour M, Krieg T, Denton CP, Saracino AM. Systemic sclerosis in adults (2022). Part I: Clinical features and pathogenesis. J Am Acad Dermatol. 2022 Feb 4:S0190-9622(22)00190-6. doi: 10.1016/j.jaad.2021.10.065. Epub ahead of print. PMID: 35131402.

Marcus Krüger

  • Izquierdo E, Vorholt D, Blakemore SJ, Sackey B, Nolte JL, Barbarino V, Schmitz JH, Nickel N, Bachurski D, Lobastova L, Nikolic M, Michalik M, Brinker R, Merkel O, Franitza M, Georgomanolis T, Neuhaus R, Koch MRK, Nasada N, Knittel G, Chapuy B, Ludwig N, Meese E, Frenzel LP, Reinhardt HC, Peifer M, Rebollido-Rios R, Bruns H, Krüger M, Hallek M,Pallasch CP (2022).Extracellular vesicles and PDL1 suppress macrophages inducing therapy resistance in TP53-deficient B-cell malignancies. Blood. 2022 Mar 28:blood.2021014007. doi: 10.1182/blood.2021014007. Epub ahead of print. PMID: 35344582.
  • Croon M, Szczepanowska K, Popovic M, Lienkamp C, Senft K, Brandscheid CP, Bock T, Gnatzy-Feik L, Ashurov A, Acton RJ, Kaul H, Pujol C, Rosenkranz S, Krüger M, Trifunovic A (2022). FGF21 modulates mitochondrial stress response in cardiomyocytes only under mild mitochondrial dysfunction.Sci Adv. 2022 Apr 8;8(14):eabn7105. doi: 10.1126/sciadv.abn7105. Epub 2022 Apr 6. PMID: 35385313; PMCID: PMC8986112.
  • Thievessen I, Suhr F, Vergarajauregui S, Böttcher RT, Brixius K, Rosenberger G, Dewald O, Fleischmann BK, Ghanem A, Krüger M, Engel FB, Fabry B, Bloch W, Fässler R (2022).The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load. Curr Biol. 2022 Jul 25;32(14):3033-3047.e9. doi: 10.1016/j.cub.2022.05.047. Epub 2022 Jun 9. PMID: 35688156.
  • Knabbe J, Protzmann J, Schneider N, Berger M, Dannehl D, Wei S, Strahle C, Tegtmeier M, Jaiswal A, Zheng H, Krüger M, Rohr K, Spanagel R, Bilbao A, Engelhardt M, Scholz H, Cambridge SB (2022). Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2122477119. doi: 10.1073/pnas.2122477119. Epub 2022 Jun 14. PMID: 35700362; PMCID: PMC9231489.
  • Das A, Thapa P, Santiago U, Shanmugam N, Banasiak K, Dąbrowska K, Nolte H, Szulc NA, Gathungu RM, Cysewski D, Krüger M, Dadlez M, Nowotny M, Camacho CJ, Hoppe T, Pokrzywa W (2022). A heterotypic assembly mechanism regulates CHIP E3 ligase activity. EMBO J. 2022 Aug 1;41(15):e109566. doi: 10.15252/embj.2021109566. Epub 2022 Jun 28. PMID: 35762422. 
  • Thievessen I, Suhr F, Vergarajauregui S, Böttcher RT, Brixius K, Rosenberger G, Dewald O, Fleischmann BK, Ghanem A, Krüger M, Engel FB, Fabry B, Bloch W, Fässler R (2022). The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load. Curr Biol. Jul 25;32(14):3033-3047.e9. doi: 10.1016/j.cub.2022.05.047. Epub Jun 9. PMID: 35688156.

Thomas Langer

  • Wani GA, Sprenger HG, Ndoci K, Chandragiri S, Acton RJ, Schatton D, Kochan SMV, Sakthivelu V, Jevtic M, Seeger JM, Müller S, Giavalisco P, Rugarli EI, Motori E, Langer T, Bergami M (2022). Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.Cell Rep. 2022 Feb 15;38(7):110370. doi: 10.1016/j.celrep.2022.110370. PMID: 35172139. 
  • Schatton D, Di Pietro G, Szczepanowska K, Veronese M, Marx MC, Braunöhler K, Barth E, Müller S, Giavalisco P, Langer T, Trifunovic A, Rugarli EI (2022). CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife. 2022 May 13;11:e74552. doi: 10.7554/eLife.74552. Epub ahead of print. PMID: 35559794.
  • Patron, M., Tarasenko, D., Nolte, H., Kroczek, L., Ghosh, M., Ohba, Y., Lasarzewski, Y., Ahmadi, Z.A., Cabrera-Orefice, A., Eyiama, A., Kellermann, T., Rugarli, E.I., Brandt, U., Meinecke, M., Langer, T(2022). Regulation of mitochondrial proteostasis by the proton gradient. EMBO J. 2022 Aug 1:e110476. Online ahead of prin,t.doi: 10.15252/embj.2021110476.
  • Ahola S, Rivera Mejías P, Hermans S, Chandragiri S, Giavalisco P, Nolte H, Langer T (2022). OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy. Cell Metab. 2022 Nov 1;34(11):1875-1891.e7. doi: 10.1016/j.cmet.2022.08.017. Epub 2022 Sep 15. PMID: 36113464.

Roman-Ulrich Müller

  • Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T,Schermer B, Schwarz G, Burst V, Müller RU (2022). A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism. Transl Res. 2022 Feb 18:S1931-5244(22)00023-8. doi: 10.1016/j.trsl.2022.02.003. Epub ahead of print. PMID: 35189406. 
  • Müller RU, Messchendorp AL, Birn H, Capasso G, Cornec-Le Gall E, Devuyst O, van Eerde A, Guirchoun P, Harris T, Hoorn EJ, Knoers NVAM, Korst U, Mekahli D, Le Meur Y, Nijenhuis T, Ong ACM, Sayer JA, Schaefer F, Servais A, Tesar V, Torra R, Walsh SB, Gansevoort RT (2022). An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International. Nephrol Dial Transplant. 2022 Apr 25;37(5):825-839. doi: 10.1093/ndt/gfab312. PMID: 35134221; PMCID: PMC9035348. 
  • Koehler FC, Späth MR, Hoyer-Allo KJR, Müller RU (2022). Mechanisms of Caloric Restriction-Mediated Stress-Resistance in Acute Kidney Injury.Nephron. 2022;146(3):234-238. doi: 10.1159/000517733. Epub 2021 Aug 2. PMID: 34340234; PMCID: PMC9216310.
  • Hoyer-Allo KJR, Späth MR, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Brönneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler FC, Grundmann F, Hackl MJ, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2022). Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney Int. 2022 May 30:S0085-2538(22)00386-6. doi: 10.1016/j.kint.2022.04.033. Epub ahead of print. PMID: 35654224.

Carien Niessen

  • Peskoller M, Bhosale A, Göbel K, Löhr J, Miceli S, Perot S, Persa O, Rübsam M, Shah J, Zhang H, Niessen CM (2022). How to Build and Regenerate a Functional Skin Barrier: The Adhesive and Cell Shaping Travels of a Keratinocyte. J Invest Dermatol. 2022 Jan 17:S0022-202X(22)00010-0. doi: 10.1016/j.jid.2021.12.034. Epub ahead of print. PMID: 35051379.
  • Rietscher K, Jahnke HG, Rübsam M, Lin EW, Has C, Omary MB, Niessen CM, Magin TM (2022). Kinase Inhibition by PKC412 Prevents Epithelial Sheet Damage in Autosomal Dominant Epidermolysis Bullosa Simplex through Keratin and Cell Contact Stabilization. J Invest Dermatol. 2022 Jun 9:S0022-202X(22)01531-7. doi: 10.1016/j.jid.2022.05.1088. Epub ahead of print. PMID: 35691363. 
  • Green KJ, Niessen CM, Rübsam M, Perez White BE, Broussard JA (2022). The Desmosome-Keratin Scaffold Integrates ErbB Family and Mechanical Signaling to Polarize Epidermal Structure and Function. Front Cell Dev Biol. 2022 May 24;10:903696. doi: 10.3389/fcell.2022.903696. PMID: 35686051; PMCID: PMC9171019.

Linda Partridge

  • Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.
  • Fraser HC, Kuan V, Johnen R, Zwierzyna M, Hingorani AD, Beyer A, Partridge L (2022). Biological mechanisms of aging predict age-related disease co-occurrence in patients. Aging Cell. 2022 Apr;21(4):e13524. doi: 10.1111/acel.13524. Epub 2022 Mar 8. PMID: 35259281; PMCID: PMC9009120.

Manolis Pasparakis  

  • Kondylis V, Schneider F, Schorn F, Oikonomou N, Straub BK, Werner S, Rosenstiel P, Pasparakis M (2022). p62 Promotes Survival and Hepatocarcinogenesis in Mice with Liver-Specific NEMO Ablation. Cancers (Basel). 2022 May 15;14(10):2436. doi: 10.3390/cancers14102436. PMID: 35626041; PMCID: PMC9139637.
  • Imai T, Van TM, Pasparakis M, Polykratis A (2022). Smooth muscle cell specific NEMO deficiency inhibits atherosclerosis in ApoE-/- mice. Sci Rep. Jul 22;12(1):12538. doi: 10.1038/s41598-022-16737-8. PMID: 35869246; PMCID: PMC9307802.
  • Jiao H, Pasparakis M (2022). Inducing Z-DNA overcomes immune checkpoint blockade resistance. Cell Res. Oct;32(10):871-872. doi: 10.1038/s41422-022-00705-y. PMID: 35915243; PMCID: PMC9525283.
  • Jiao H, Wachsmuth L, Wolf S, Lohmann J, Nagata M, Kaya GG, Oikonomou N, Kondylis V, Rogg M, Diebold M, Tröder SE, Zevnik B, Prinz M, Schell C, Young GR, Kassiotis G, Pasparakis M (2022). ADAR1 averts fatal type I interferon induction by ZBP1. Nature. Jul;607(7920):776-783. doi: 10.1038/s41586-022-04878-9. PMID: 35859176; PMCID: PMC9329096.
  • Kopelyanskiy D, Desponds C, Prevel F, Rossi M, Migliorini R, Snäkä T, Eren RO, Claudinot S, Lye LF, Pasparakis M, Beverley SM, Fasel N (2022). Leishmania guyanensis suppressed inducible nitric oxide synthase provoked by its viral endosymbiont. Front Cell Infect Microbiol. 2022 Aug 12;12:944819. doi: 10.3389/fcimb.2022.944819. PMID: 36034693; PMCID: PMC9416488.

M. de las Nieves Peltzer 

  • Peltzer N (2022). Linear ubiquitin as a common regulator of cellular stress. FEBS J. 2022 Mar 16. doi: 10.1111/febs.16427. Epub ahead of print. PMID: 35293134.
  • Hildebrandt X, Ibrahim M, Peltzer N (2022). Cell death and inflammation during obesity: "Know my methods, WAT(son)". Cell Death Differ. 2022 Sep 29:1–14. doi: 10.1038/s41418-022-01062-4. Epub ahead of print. PMID: 36175539; PMCID: PMC9520110.

Lena Pernas

  • Li X, Straub J, Medeiros TC, Mehra C, den Brave F, Peker E, Atanassov I, Stillger K, Michaelis JB, Burbridge E, Adrain C, Münch C, Riemer J, Becker T, Pernas LF (2022). Mitochondria shed their outer membrane in response to infection-induced stress. Science. 2022 Jan 14;375(6577):eabi4343. doi: 10.1126/science.abi4343. Epub 2022 Jan 14. PMID: 35025629.

Dominik Pesta

  • Pesta D, Jordan J (2022).INDY as a Therapeutic Target for Cardio-Metabolic Disease. Metabolites. 2022 Mar 14;12(3):244. doi: 10.3390/metabo12030244. PMID: 35323687; PMCID: PMC8949283.
  • Jelenik T, Kodde A, Pesta D, Phielix E, Oosting A, Rohbeck E, Dewidar B, Mastrototaro L, Trenkamp S, Keijer J, van der Beek EM, Roden M (2022). Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming. Pharmacol Res. 2022 Mar 28;179:106193. doi: 10.1016/j.phrs.2022.106193. Epub ahead of print. PMID: 35358682.
  • Pafili K, Kahl S, Mastrototaro L, Strassburger K, Pesta D, Herder C, Pützer J, Dewidar B, Hendlinger M, Granata C, Saatmann N, Yavas A, Gancheva S, Heilmann G, Esposito I, Schlensak M, Roden M (2022). Mitochondrial respiration is decreased in visceral but not subcutaneous adipose tissue in obese individuals with fatty liver disease. J Hepatol. Aug 19:S0168-8278(22)03010-0. doi: 10.1016/j.jhep.2022.08.010. Epub ahead of print. PMID: 35988689.

Christina Polidori

  • Heeß A, Meyer AM, Becker I, Noetzel N, Verleysdonk J, Rarek M, Benzing T, Polidori MC (2021). The prognostic fingerprint of quality of life in older inpatients : Relationship to geriatric syndromes' and resources' profile. Z Gerontol Geriatr. 2022 Feb;55(1):38-43. English. doi: 10.1007/s00391-021-01978-5. Epub 2021 Oct 6. PMID: 34617144. 
  • Meyer AM, Pickert L, Heeß A, Becker I, Kurschat C, Bartram MP, Benzing T, Polidori MC (2022). Prognostic Signature of Chronic Kidney Disease in Advanced Age: Secondary Analysis from the InGAH Study with One-Year Follow-Up. Biomolecules. 2022 Mar 9;12(3):423. doi: 10.3390/biom12030423. PMID: 35327615; PMCID: PMC8946591.
  • Zampino M, Polidori MC, Ferrucci L, O'Neill D, Pilotto A, Gogol M, Rubenstein L (2022). Biomarkers of aging in real life: three questions on aging and the comprehensive geriatric assessment. Geroscience. Jul 7. doi: 10.1007/s11357-022-00613-4. PMID: 35796977.

Alfredo Ramirez

  • Martino Adami PV, Orellana A, García P, Kleineidam L, Alarcón-Martín E, Montrreal L, Aguilera N, Espinosa A, Abdelnour C, Rosende-Roca M, Tartari JP, Vargas L, Mauleón A, Esteban-De Antonio E, López-Cuevas R, Dalmasso MC, Martin RC, Parveen K, Andrade Fuentes VM, Amin N, Ahmad S, Ikram MA, Lewczuk P, Kornhuber J, Peters O, Frölich L, Rüther E, Wiltfang J, Tarraga L, Boada M, Maier W, de Rojas I, Cano A, Sanabria A, Alegret M, Hernández I, Marquié M, Valero S, van Duijn CM, Wagner M, Jessen F, Schneider A, Sáez Goñi ME, Pérez AG, Ruiz A, Ramírez A (2022). Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer's type. Brain. 2022 Jan 28:awac024. doi: 10.1093/brain/awac024. Epub ahead of print. PMID: 35088840.
  • Belloy ME, Eger SJ, Le Guen Y, Damotte V, Ahmad S, Ikram MA, Ramirez A, Tsolaki AC, Rossi G, Jansen IE, de Rojas I, Parveen K, Sleegers K, Ingelsson M, Hiltunen M, Amin N, Andreassen O, Sánchez-Juan P, Kehoe P, Amouyel P, Sims R, Frikke-Schmidt R, van der Flier WM, Lambert JC; European Alzheimer & Dementia BioBank (EADB), He Z, Han SS, Napolioni V, Greicius MD (2022). Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping. Alzheimers Res Ther. 2022 Feb 4;14(1):22. doi: 10.1186/s13195-022-00962-4. PMID: 35120553; PMCID: PMC8815198.
  • Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, Düzel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Pomara N, Preis L, Priller J, Ramírez A, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Jessen F, Heneka MT. Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. J Alzheimers Dis. 2022;85(3):1267-1282. doi: 10.3233/JAD-215196. PMID: 34924387.
  • Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W Jr, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, Tosto G, Traykov L, Tremolizzo L, Tybjærg-Hansen A, Uitterlinden A, Ullgren A, Ulstein I, Valero S, Valladares O, Broeckhoven CV, Vance J, Vardarajan BN, van der Lugt A, Dongen JV, van Rooij J, van Swieten J, Vandenberghe R, Verhey F, Vidal JS, Vogelgsang J, Vyhnalek M, Wagner M, Wallon D, Wang LS, Wang R, Weinhold L, Wiltfang J, Windle G, Woods B, Yannakoulia M, Zare H, Zhao Y, Zhang X, Zhu C, Zulaica M; EADB; GR@ACE; DEGESCO; EADI; GERAD; Demgene; FinnGen; ADGC; CHARGE, Farrer LA, Psaty BM, Ghanbari M, Raj T, Sachdev P, Mather K, Jessen F, Ikram MA, de Mendonça A, Hort J, Tsolaki M, Pericak-Vance MA, Amouyel P, Williams J, Frikke-Schmidt R, Clarimon J, Deleuze JF, Rossi G, Seshadri S, Andreassen OA, Ingelsson M, Hiltunen M, Sleegers K, Schellenberg GD, van Duijn CM, Sims R, van der Flier WM, Ruiz A, Ramirez A, Lambert JC (2022). New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet.2022 Apr;54(4):412-436. doi: 10.1038/s41588-022-01024-z. Epub 2022 Apr 4. PMID: 35379992; PMCID: PMC9005347. 
  • Gerards M, Schild AK, Meiberth D, Rostamzadeh A, Vehreschild JJ, Wingen-Heimann S, Johannis W, Martino Adami P, Onur OA, Ramirez A, Karikari TK, Ashton NJ, Zetterberg H, Blennow K, Maier F, Jessen F(2022). Alzheimer's Disease Plasma Biomarkers Distinguish Clinical Diagnostic Groups in Memory Clinic Patients. Dement Geriatr Cogn Disord. 2022 May 3:1-11. doi: 10.1159/000524390. Epub ahead of print. PMID: 35504263.
  • Wolfsgruber S, Kleineidam L, Weyrauch AS, Barkhoff M, Röske S, Peters O, Preis L, Gref D, Spruth EJ, Altenstein S, Priller J, Fließbach K, Schneider A, Wiltfang J, Bartels C, Jessen F, Maier F, Düzel E, Metzger C, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Kilimann I, Teipel S, Laske C, Munk MH, Roy N, Spottke A, Ramirez A, Heneka MT, Brosseron F, Wagner M; DELCODE study group (2022). Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease. J Alzheimers Dis. 2022;87(2):545-555. doi: 10.3233/JAD-215416. PMID: 35275535. 
  • Le Guen Y, Belloy ME, Grenier-Boley B, de Rojas I, Castillo-Morales A, Jansen I, Nicolas A, Bellenguez C, Dalmasso C, Küçükali F, Eger SJ, Rasmussen KL, Thomassen JQ, Deleuze JF, He Z, Napolioni V, Amouyel P, Jessen F, Kehoe PG, van Duijn C, Tsolaki M, Sánchez-Juan P, Sleegers K, Ingelsson M, Rossi G, Hiltunen M, Sims R, van der Flier WM, Ramirez A, Andreassen OA, Frikke-Schmidt R, Williams J, Ruiz A, Lambert JC, Greicius MD; Members of the EADB, GR@ACE, DEGESCO, DemGene, GERAD, and EADI Groups, Arosio B, Benussi L, Boland A, Borroni B, Caffarra P, Daian D, Daniele A, Debette S, Dufouil C, Düzel E, Galimberti D, Giedraitis V, Grimmer T, Graff C, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Holstege H, Hort J, Jürgen D, Kuulasmaa T, van der Lugt A, Masullo C, Mecocci P, Mehrabian S, de Mendonça A, Moebus S, Nacmias B, Nicolas G, Olaso R, Papenberg G, Parnetti L, Pasquier F, Peters O, Pijnenburg YAL, Popp J, Rainero I, Ramakers I, Riedel-Heller S, Scarmeas N, Scheltens P, Scherbaum N, Schneider A, Seripa D, Soininen H, Solfrizzi V, Spalletta G, Squassina A, van Swieten J, Tegos TJ, Tremolizzo L, Verhey F, Vyhnalek M, Wiltfang J, Boada M, García-González P, Puerta R, Real LM, Álvarez V, Bullido MJ, Clarimon J, García-Alberca JM, Mir P, Moreno F, Pastor P, Piñol-Ripoll G, Molina-Porcel L, Pérez-Tur J, Rodríguez-Rodríguez E, Royo JL, Sánchez-Valle R, Dichgans M, Rujescu D (2022). Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease. JAMA Neurol. 2022 Jul 1;79(7):652-663. doi: 10.1001/jamaneurol.2022.1166. PMID: 35639372; PMCID: PMC9157381
  • Billette OV, Ziegler G, Aruci M, Schütze H, Kizilirmak JM, Richter A, Altenstein S, Bartels C, Brosseron F, Cardenas-Blanco A, Dahmen P, Dechent P, Dobisch L, Fliessbach K, Freiesleben SD, Glanz W, Göerß D, Haynes JD, Heneka MT, Kilimann I, Kimmich O, Kleineidam L, Laske C, Lohse A, Rostamzadeh A, Metzger C, Munk MH, Peters O, Preis L, Priller J, Scheffler K, Schneider A, Spottke A, Spruth EJ, Ramirez A, Röske S, Roy N, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Yakupov R, Zeidman P, Jessen F, Schott BH, Düzel E, Maass A; DELCODE Study Group (2022). Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease. Neurology. Aug 23;99(8):e775-e788. doi: 10.1212/WNL.0000000000200667. Epub Jun 3. PMID: 35995589; PMCID: PMC9484732.
  • Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, Vromen EM, Wightman DP, Alcolea D, Alegret M, Alvarez I, Amouyel P, Athanasiu L, Bahrami S, Bailly H, Belbin O, Bergh S, Bertram L, Biessels GJ, Blennow K, Blesa R, Boada M, Boland A, Buerger K, Carracedo Á, Cervera-Carles L, Chene G, Claassen JAHR, Debette S, Deleuze JF, de Deyn PP, Diehl-Schmid J, Djurovic S, Dols-Icardo O, Dufouil C, Duron E, Düzel E; EADB consortium, Fladby T, Fortea J, Frölich L, García-González P, Garcia-Martinez M, Giegling I, Goldhardt O, Gobom J, Grimmer T, Haapasalo A, Hampel H, Hanon O, Hausner L, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herukka SK, Holstege H, Jarholm J, Kern S, Knapskog AB, Koivisto AM, Kornhuber J, Kuulasmaa T, Lage C, Laske C, Leinonen V, Lewczuk P, Lleó A, de Munain AL, Lopez-Garcia S, Maier W, Marquié M, Mol MO, Montrreal L, Moreno F, Moreno-Grau S, Nicolas G, Nöthen MM, Orellana A, Pålhaugen L, Papma JM, Pasquier F, Perneczky R, Peters O, Pijnenburg YAL, Popp J, Posthuma D, Pozueta A, Priller J, Puerta R, Quintela I, Ramakers I, Rodriguez-Rodriguez E, Rujescu D, Saltvedt I, Sanchez-Juan P, Scheltens P, Scherbaum N, Schmid M, Schneider A, Selbæk G, Selnes P, Shadrin A, Skoog I, Soininen H, Tárraga L, Teipel S; GR@ACE study group, Tijms B, Tsolaki M, Van Broeckhoven C, Van Dongen J, van Swieten JC, Vandenberghe R, Vidal JS, Visser PJ, Vogelgsang J, Waern M, Wagner M, Wiltfang J, Wittens MMJ, Zetterberg H, Zulaica M, van Duijn CM, Bjerke M, Engelborghs S, Jessen F, Teunissen CE, Pastor P, Hiltunen M, Ingelsson M, Andreassen OA, Clarimón J, Sleegers K, Ruiz A, Ramirez A, Cruchaga C, Lambert JC, van der Flier W (2022). Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathol. 2022 Nov;144(5):821-842. doi: 10.1007/s00401-022-02454-z. Epub 2022 Sep 6. PMID: 36066633; PMCID: PMC9547780.

Christian Reinhardt

  • Izquierdo E, Vorholt D, Blakemore SJ, Sackey B, Nolte JL, Barbarino V, Schmitz JH, Nickel N, Bachurski D, Lobastova L, Nikolic M, Michalik M, Brinker R, Merkel O, Franitza M, Georgomanolis T, Neuhaus R, Koch MRK, Nasada N, Knittel G, Chapuy B, Ludwig N, Meese E, Frenzel LP, Reinhardt HC, Peifer M, Rebollido-Rios R, Bruns H, Krüger M, Hallek M, Pallasch CP (2022).Extracellular vesicles and PDL1 suppress macrophages inducing therapy resistance in TP53-deficient B-cell malignancies. Blood. 2022 Mar 28:blood.2021014007. doi: 10.1182/blood.2021014007. Epub ahead of print. PMID: 35344582.
  • Werr L, Plenker D, Dammert MA, Lorenz C, Brägelmann J, Tumbrink HL, Klein S, Schmitt A, Büttner R, Persigehl T, Shokat KM,Wunderlich FT, Schram AM, Peifer M, Sos ML, Reinhardt HC, Thomas RK (2022). CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization. Mol Cancer Ther. 2022 May 4;21(5):821-830. doi: 10.1158/1535-7163.MCT-21-0820. PMID: 35247925.
  • Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling CD, Nieper P, Feldmann T, Merkel O, Lorsy E, da Palma Guerreiro A, von Jan J, Kisis I, Wasserburger E, Claasen J, Faitschuk-Meyer E, Altmüller J, Nürnberg P, Yang TP, Lienhard M, Herwig R, Kreuzer KA, Pallasch CP, Buettner R, Schäfer SC, Hartley J, Abken H, Peifer M, Kashkar H, Knittel G, Eichhorst B, Ullrich RT, Herling M, Reinhardt HC, Hallek M, Schweiger MR, Frenzel LP (2022). Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies. Blood. 2022 Jun 15:blood.2021014304. doi: 10.1182/blood.2021014304. Epub ahead of print. PMID: 35704690.
  • Pindzola GM, Razzaghi R, Tavory RN, Nguyen HT, Morris VM, Li M, Agarwal S, Huang B, Okada T, Reinhardt HC, Knittel G, Kashkar H, Young RM, Pittaluga S, Muppidi JR (2022). Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma. Blood. 2022 Jun 27:blood.2022015926. doi: 10.1182/blood.2022015926. Epub ahead of print. PMID: 35759728.
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Jane Reznick

  • Park TJ, Reznick J (2022). Journal of muscle research and cell motility, focus on Extreme Physiology Extreme Tolerance to Hypoxia, Hypercapnia, and Pain in the Naked Mole-Rat. J Muscle Res Cell Motil. Jul 19. doi: 10.1007/s10974-022-09623-3. Epub ahead of print. PMID: 35854159.

Jan Riemer

  • Li X, Straub J, Medeiros TC, Mehra C, den Brave F, Peker E, Atanassov I, Stillger K, Michaelis JB, Burbridge E, Adrain C, Münch C, Riemer J, Becker T, Pernas LF(2022). Mitochondria shed their outer membrane in response to infection-induced stress. Science. 2022 Jan 14;375(6577):eabi4343. doi: 10.1126/science.abi4343. Epub 2022 Jan 14. PMID: 35025629.
  • Bolgi O, Silva-Garcia M, Ross B, Pilla E, Kari V, Killisch M, Spitzner M, Stark N, Lenz C, Weiss K, Donzelli L, Gorrell MD, Grade M, Riemer J, Urlaub H, Dobbelstein M, Huber R, Geiss-Friedlander R (2022). Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair. EMBO Rep. Oct 6;23(10):e54136. doi: 10.15252/embr.202154136. Epub Aug 1. PMID: 35912982; PMCID: PMC9535758.
  • Jacobs LJHC, Riemer J (2022). Maintenance of small molecule redox homeostasis in mitochondria. FEBS Lett. 2022 Aug 27. doi: 10.1002/1873-3468.14485. Epub ahead of print. PMID: 36030088.

Elena Rugarli

  • Wani GA, Sprenger HG, Ndoci K, Chandragiri S, Acton RJ, Schatton D, Kochan SMV, Sakthivelu V, Jevtic M, Seeger JM, Müller S, Giavalisco P, Rugarli EI, Motori E, Langer T, Bergami M (2022). Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.Cell Rep. 2022 Feb 15;38(7):110370. doi: 10.1016/j.celrep.2022.110370. PMID: 35172139.
  • Schatton D, Di Pietro G, Szczepanowska K, Veronese M, Marx MC, Braunöhler K, Barth E, Müller S, Giavalisco P,Langer T, Trifunovic A, Rugarli EI (2022). CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife. 2022 May 13;11:e74552. doi: 10.7554/eLife.74552. Epub ahead of print. PMID: 35559794.
  • Ralevski A, Apelt F, Olas JJ, Mueller-Roeber B, Rugarli EI, Kragler F, Horvath TL (2022). Plant mitochondrial FMT and its mammalian homolog CLUH controls development and behavior in Arabidopsis and locomotion in mice. Cell Mol Life Sci. , 2022 Jun 2;79(6):334. doi: 10.1007/s00018-022-04382-3. PMID: 35652974.
  • Patron M, Tarasenko D, Nolte H, Kroczek L, Ghosh M, Ohba Y, Lasarzewski Y, Ahmadi ZA, Cabrera-Orefice A, Eyiama A, Kellermann T, Rugarli EI, Brandt U, Meinecke M, Langer T (2022). Regulation of mitochondrial proteostasis by the proton gradient. EMBO J. 2022 Aug 16;41(16):e110476. doi: 10.15252/embj.2021110476. Epub Aug 1. PMID: 35912435; PMCID: PMC9379554.

Bernhard Schermer

  • Butt L, Unnersjö-Jess D, Höhne M, Hahnfeldt R, Reilly D, Rinschen MM, Plagmann I, Diefenhardt P, Brähler S, Brinkkötter PT, Brismar H, Blom H, Schermer B, Benzing T (2021). Super-Resolution Imaging of the Filtration Barrier Suggests a Role for Podocin R229Q in Genetic Predisposition to Glomerular Disease. J Am Soc Nephrol. 2022 Jan;33(1):138-154. doi: 10.1681/ASN.2020060858. Epub 2021 Dec 1. PMID: 34853150.
  • Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T, Schermer B, Schwarz G, Burst V, Müller RU (2022). A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism. Transl Res. 2022 Feb 18:S1931-5244(22)00023-8. doi: 10.1016/j.trsl.2022.02.003. Epub ahead of print. PMID: 35189406.
  • Reusch B, Bartram MP, Dafinger C, Palacio-Escat N, Wenzel A, Fenton RA, Saez-Rodriguez J, Schermer B, Benzing T, Altmüller J, Beck BB, Rinschen MM (2022). MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells. J Proteomics. 2022 Feb 10;252:104424. doi: 10.1016/j.jprot.2021.104424. Epub 2021 Nov 12. PMID: 34775100. 
  • Hoyer-Allo KJR, Späth MR, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Brönneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler FC, Grundmann F, Hackl MJ, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2022). Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney Int. 2022 May 30:S0085-2538(22)00386-6. doi: 10.1016/j.kint.2022.04.033. Epub ahead of print. PMID: 35654224.

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Björn Schumacher

  • Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.
  • Umansky C, Morellato AE, Rieckher M, Scheidegger MA, Martinefski MR, Fernández GA, Pak O, Kolesnikova K, Reingruber H, Bollini M, Crossan GP, Sommer N, Monge ME, Schumacher B, Pontel LB (2022). Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity. Nat Commun. 2022 Feb 8;13(1):745. doi: 10.1038/s41467-022-28242-7. PMID: 35136057; PMCID: PMC8827065.
  • Soltanmohammadi N, Wang S, Schumacher B (2022). Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy. Nat Commun. 2022 Feb 4;13(1):701. doi: 10.1038/s41467-022-28225-8. PMID: 35121747; PMCID: PMC8816960. 
  • Volatier T, Schumacher B, Cursiefen C, Notara M (2022). UV Protection in the Cornea: Failure and Rescue. Biology (Basel). 2022 Feb 10;11(2):278. doi: 10.3390/biology11020278. PMID: 35205145; PMCID: PMC8868636.
  • Vaddavalli PL, Schumacher B (2022). The p53 network: cellular and systemic DNA damage responses in cancer and aging. Trends Genet. 2022 Mar 25:S0168-9525(22)00037-3. doi: 10.1016/j.tig.2022.02.010. Epub ahead of print. PMID: 35346511. 
  • Kasper P, Selle J, Vohlen C, Wilke R, Kuiper-Makris C, Klymenko O, Bae-Gartz I, Schömig C, Quaas A, Schumacher B, Demir M, Bürger M, Lang S, Martin A, Steffen HM, Goeser T, Dötsch J, Alcazar MAA (2022). Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice. Int J Mol Sci. 2022 May 17;23(10):5609. doi: 10.3390/ijms23105609. PMID: 35628414; PMCID: PMC9144113.

Phillipp Steven

  • Gehlsen U, Faust C, Blecha C, Dietrich-Ntoukas T, Eberwein P, Issleib S, Meyer-Ter-Vehn T, Braun R, Westekemper H, Steven P (2022). Outcomes and complications of cataract surgery in patients with chronic ocular graft-versus-host-disease-a multicenter, retrospective analysis. Graefes Arch Clin Exp Ophthalmol. 2022 Mar 7. doi: 10.1007/s00417-022-05613-w. Epub ahead of print. PMID: 35254513.
  • Setu MAK, Schmidt S, Musial G, Stern ME, Steven P (2022). Segmentation and Evaluation of Corneal Nerves and Dendritic Cells From In Vivo Confocal Microscopy Images Using Deep Learning. Transl Vis Sci Technol. 2022 Jun 1;11(6):24. doi: 10.1167/tvst.11.6.24. PMID: 35762938; PMCID: PMC9251793.
  • Gehlsen U, Faust C, Blecha C, Dietrich-Ntoukas T, Eberwein P, Issleib S, Meyer-Ter-Vehn T, Braun R, Westekemper H, Steven P (2022). Outcomes and complications of cataract surgery in patients with chronic ocular graft-versus-host-disease-a multicenter, retrospective analysis. Graefes Arch Clin Exp Ophthalmol. Aug;260(8):2613-2622. doi: 10.1007/s00417-022-05613-w. Epub 2022 Mar 7. PMID: 35254513; PMCID: PMC9325851.
  • Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P (2022). Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease. Transplant Cell Ther. Jul 31:S2666-6367(22)01514-7. doi: 10.1016/j.jtct.2022.07.027. Epub ahead of print. PMID: 35921986.
  • Katsinas N, Gehlsen U, García-Posadas L, Rodríguez-Rojo S, Steven P, González-García MJ, Enríquez-de-Salamanca A (2022). Olive Pomace Phenolic Compounds: From an Agro-Industrial By-Product to a Promising Ocular Surface Protection for Dry Eye Disease. J Clin Med. 2022 Aug 11;11(16):4703. doi: 10.3390/jcm11164703. PMID: 36012942; PMCID: PMC9409789.

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Peter Tessarz

  • Demetriadou C, Raoukka A, Charidemou E, Mylonas C, Michael C, Parekh S, Koufaris C, Skourides P, Papageorgis P, Tessarz P, Kirmizis A (2022). Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance. Oncogene. 2022 Jan;41(4):571-585. doi: 10.1038/s41388-021-02113-9. Epub 2021 Nov 16. PMID: 34785778; PMCID: PMC8782725.
  • Gehling K, Parekh S, Schneider F, Kirchner M, Kondylis V, Nikopoulou C, Tessarz P (2022). RNA-sequencing of single cholangiocyte-derived organoids reveals high organoid-to organoid variability. Life Sci Alliance. Aug 1;5(12):e202101340. doi: 10.26508/lsa.202101340. PMID: 35914813; PMCID: PMC9348635.
  • Bozukova M, Nikopoulou C, Kleinenkuhnen N, Grbavac D, Goetsch K, Tessarz P (2022). Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver. Mol Syst Biol. 2022 Sep;18(9):e11002. doi: 10.15252/msb.202211002. PMID: 36082605; PMCID: PMC9459415.

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Marc Tittgemeyer

  • Hanssen R, Thanarajah SE, Tittgemeyer M, Brüning JC (2022). Obesity - A Matter of Motivation? Exp Clin Endocrinol Diabetes. 2022 Feb 18. doi: 10.1055/a-1749-4852. Epub ahead of print. PMID: 35181879.
  • Trempler I, Binder E, Reuter M, Plieger T, Standke I, Mecklenbrauck F, Meinert S, Forstner AJ, Nöthen MM, Rietschel M, Stürmer S, Dannlowski U, Tittgemeyer M, Lencer R, Fink GR, Schubotz RI (2022). Effects of DRD2/ANKK1 and COMT Val158Met polymorphisms on stabilization against and adaptation to unexpected events. Cereb Cortex. 2022 Mar 2:bhac046. doi: 10.1093/cercor/bhac046. Epub ahead of print. PMID: 35235645.
  • Pelzer EA, Stürmer S, Feis DL, Melzer C, Schwartz F, Scharge M, Eggers C, Tittgemeyer M, Timmermann L (2022). Clustering of Parkinson subtypes reveals strong influence of DRD2 polymorphism and gender. Sci Rep. 2022 Apr 11;12(1):6038. doi: 10.1038/s41598-022-09657-0. PMID: 35411010; PMCID: PMC9001640.
  • Steidel K, Ruppert MC, Greuel A, Tahmasian M, Maier F, Hammes J, van Eimeren T, Timmermann L, Tittgemeyer M,Drzezga A, Pedrosa DJ, Eggers C (2022).Longitudinal trimodal imaging of midbrain-associated network degeneration in Parkinson's disease. NPJ Parkinsons Dis. 2022 Jun 22;8(1):79. doi: 10.1038/s41531-022-00341-8. PMID: 35732679; PMCID: PMC9218128.
  • Oren S, Tittgemeyer M, Rigoux L, Schlamann M, Schonberg T, Kuzmanovic B (2022). Neural encoding of food and monetary reward delivery. Neuroimage. 2022 Aug 15;257:119335. doi: 10.1016/j.neuroimage.2022.119335. Epub 2022 May 26. PMID: 35643268.

Achim Tresch

  • Baar T, Dümcke S, Gressel S, Schwalb B, Dilthey A, Cramer P, Tresch A (2022). RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history. G3 (Bethesda).2022 Mar 7:jkac054. doi: 10.1093/g3journal/jkac054. Epub ahead of print. PMID: 35253846.

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Aleksandra Trifunovic

  • Rumyantseva A, Popovic M, Trifunovic A (2022). CLPP deficiency ameliorates neurodegeneration caused by impaired mitochondrial protein synthesis. Brain. 2022 Mar 29;145(1):92-104. doi: 10.1093/brain/awab303. PMID: 35240691.
  • Croon M, Szczepanowska K, Popovic M, Lienkamp C, Senft K, Brandscheid CP, Bock T, Gnatzy-Feik L, Ashurov A, Acton RJ, Kaul H, Pujol C, Rosenkranz S,Krüger M, Trifunovic A (2022).FGF21 modulates mitochondrial stress response in cardiomyocytes only under mild mitochondrial dysfunction. Sci Adv. 2022 Apr 8;8(14):eabn7105. doi: 10.1126/sciadv.abn7105. Epub 2022 Apr 6. PMID: 35385313; PMCID: PMC8986112.
  • Schatton D, Di Pietro G, Szczepanowska K, Veronese M, Marx MC, Braunöhler K, Barth E, Müller S, Giavalisco P,Langer T, Trifunovic A, Rugarli EI (2022). CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife. 2022 May 13;11:e74552. doi: 10.7554/eLife.74552. Epub ahead of print. PMID: 35559794.
  • Salscheider SL, Gerlich S, Cabrera-Orefice A, Peker E, Rothemann RA, Murschall LM, Finger Y, Szczepanowska K, Ahmadi ZA, Guerrero-Castillo S, Erdogan A, Becker M, Ali M, Habich M, Petrungaro C, Burdina N, Schwarz G, Klußmann M, Neundorf I, Stroud DA, Ryan MT, Trifunovic A, Brandt U, Riemer J (2022). AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5. EMBO J. Sep 1;41(17):e110784. doi: 10.15252/embj.2022110784. Epub 2022 Jul 20. PMID: 35859387; PMCID: PMC9434101.
  • Ravanelli S, Li Q, Annibal A, Trifunovic A, Antebi A, Hoppe T (2022). Reprograming of proteasomal degradation by branched chain amino acid metabolism. Aging Cell. 2022 Sep 27:e13725. doi: 10.1111/acel.13725. Epub ahead of print. PMID: 36168305.

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Mirka Uhlirova

  • Külshammer E, Kilinc M, Csordás G, Bresser T, Nolte H, Uhlirova M (2022). The mechanosensor Filamin A/Cheerio promotes tumourigenesis via specific interactions with components of the cell cortex. FEBS J. 2022 Feb 21. doi: 10.1111/febs.16408. Epub ahead of print. PMID: 35191183.

David Vilchez

  • Zhang WH, Koyuncu S, Vilchez D. Insights Into the Links Between Proteostasis and Aging From C. elegans. Front Aging (2022) Mar 18;3:854157. doi: 10.3389/fragi.2022.854157. PMID: 35821832; PMCID: PMC9261386.

Dario Valenzano

  • Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.
  • Promislow D, Anderson RM, Scheffer M, Crespi B, DeGregori J, Harris K, Horowitz BN, Levine ME, Riolo MA, Schneider DS, Spencer SL, Valenzano DR, Hochberg ME (2022). Resilience integrates concepts in aging research. iScience. 2022 Apr 6;25(5):104199. doi: 10.1016/j.isci.2022.104199. PMID: 35494229; PMCID: PMC9044173.

Johannes Vogt

  • Bitar L, Uphaus T, Thalman C, Muthuraman M, Gyr L, Ji H, Domingues M, Endle H, Groppa S, Steffen F, Koirala N, Fan W, Ibanez L, Heitsch L, Cruchaga C, Lee JM, Kloss F, Bittner S, Nitsch R, Zipp F, Vogt J (2022).Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke. Sci Transl Med. 2022 Apr 20;14(641):eabk0135. doi: 10.1126/scitranslmed.abk0135. Epub 2022 Apr 20. PMID: 35442704.

Henning Walczak

  • Zinngrebe J, Moepps B, Monecke T, Gierschik P, Schlichtig F, Barth TFE, Strauß G, Boldrin E, Posovszky C, Schulz A, Beringer O, Rieser E, Jacobsen EM, Lorenz MR, Schwarz K, Pannicke U, Walczak H, Niessing D, Schuetz C, Fischer-Posovszky P, Debatin KM (2022). Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS. EMBO Mol Med. 2022 Mar 7;14(3):e14901. doi: 10.15252/emmm.202114901. Epub 2022 Feb 16. PMID: 35170849; PMCID: PMC8899767.
  • Li X, Huang CH, Sánchez-Rivera FJ, Kennedy MC, Tschaharganeh DF, Morris JP 4th, Montinaro A, O'Rourke KP, Banito A, Wilkinson JE, Chen CC, Ho YJ, Dow LE, Tian S, Luan W, de Stanchina E, Zhang T, Gray NS, Walczak H, Lowe SW (2022). A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2110557119. doi: 10.1073/pnas.2110557119. Epub 2022 Apr 20. PMID: 35442775.
  • Theobald SJ, Simonis A, Mudler JM, Göbel U, Acton R, Kohlhas V, Albert MC, Hellmann AM, Malin JJ, Winter S, Hallek M, Walczak H, Nguyen PH, Koch M, Rybniker J (2022). Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS-CoV-2 mRNA vaccination. EMBO Mol Med. Jul 4:e15888. doi: 10.15252/emmm.202215888. PMID: 35785445.

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Rudolf Wiesner

  • Franko A, Irmler M, Prehn C, Heinzmann SS, Schmitt-Kopplin P, Adamski J, Beckers J, von Kleist-Retzow JC,Wiesner R, Häring HU, Heni M, Birkenfeld AL, de Angelis MH (2022). Bezafibrate Reduces Elevated Hepatic Fumarate in Insulin-Deficient Mice. Biomedicines. 2022 Mar 6;10(3):616. doi: 10.3390/biomedicines10030616. PMID: 35327418; PMCID: PMC8945094.
  • Urbanczyk S, Baris OR, Hofmann J, Taudte RV, Guegen N, Golombek F, Castiglione K, Meng X, Bozec A, Thomas J, Weckwerth L, Mougiakakos D, Schulz SR, Schuh W, Schlötzer-Schrehardt U, Steinmetz TD, Brodesser S, Wiesner RJ, Mielenz D (2022).Mitochondrial respiration in B lymphocytes is essential for humoral immunity by controlling the flux of the TCA cycle. Cell Rep. 2022 Jun 7;39(10):110912. doi: 10.1016/j.celrep.2022.110912. PMID: 35675769.
  • Kimoloi S, Sen A, Guenther S, Braun T, Brügmann T, Sasse P, Wiesner RJ, Pla-Martín D, Baris OR (2022). Combined fibre atrophy and decreased muscle regeneration capacity driven by mitochondrial DNA alterations underlie the development of sarcopenia. J Cachexia Sarcopenia Muscle. 2022 Jun 28. doi: 10.1002/jcsm.13026. Epub ahead of print. PMID: 35765148.

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Thomas Wunderlich

  • Werr L, Plenker D, Dammert MA, Lorenz C, Brägelmann J, Tumbrink HL, Klein S, Schmitt A, Büttner R, Persigehl T, Shokat KM, Wunderlich FT, Schram AM, Peifer M, Sos ML, Reinhardt HC, Thomas RK (2022). CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization. Mol Cancer Ther. 2022 May 4;21(5):821-830. doi: 10.1158/1535-7163.MCT-21-0820. PMID: 35247925.

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Andreas Wodarz

  • Pryymachuk G, El-Awaad E, Piekarek N, Drebber U, Maul AC, Hescheler J, Wodarz A, Pfitzer G, Neiss WF, Pietsch M, Schroeter MM (2022). Angiotensin II type 1 receptor localizes at the blood-bile barrier in humans and pigs. Histochem Cell Biol. 2022 Feb 28. doi: 10.1007/s00418-022-02087-z. Epub ahead of print. PMID: 35229169.

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Branko Zevnik

  • Tröder SE, Zevnik B (2022). Simple electroporation for efficient CRISPR/Cas9 genome editing in murine zygotes V.4. Protocols.oi. Jan doi: 10.17504/protocols.io.b4dyqs7w.
  • Tröder SE, Zevnik B (2022). History of genome editing: From meganucleases to CRISPR. Lab Anim.  Feb;56(1):60-68. doi: 10.1177/0023677221994613. PMID: 33622064.
  • Stephan A, Rehberg M, Tröder S, Zevnik B, Niehoff A, Etich J, Semler O, Zaucke F (2022). Homozygous Kdelr2-mutant mice display defects in endochondral and intramembranous bone development. Bone Reports. May 1;16:10128
  • Zevnik B, Jerchow B, Buch T (2022). 3R measures in facilities for the production of genetically modified rodents. Lab Anim (NY). Jun;51(6):162-177. doi: 10.1038/s41684-022-00978-1. PMID: 35641635.
  • Jiao H, Wachsmuth L, Wolf S, Lohmann J, Nagata M, Kaya GG, Oikonomou N, Kondylis V, Rogg M, Diebold M, Tröder SE, Zevnik B, Prinz M, Schell C, Young GR, Kassiotis G, Pasparakis M (2022). ADAR1 averts fatal type I interferon induction by ZBP1. Nature. Jul;607(7920):776-783. doi: 10.1038/s41586-022-04878-9. PMID: 35859176; PMCID: PMC9329096.

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