CECAD Scientists Receive DFG Funding for Proteostasis Research

31.03.2025 Research Group Leaders 2025 TopNews Grants Prof. Dr. Thorsten Hoppe Prof. Dr. David Vilchez

proteostasis research. the little men are working on a toy human muscle and one can see both tools to build a house or to dispose of biological material, like trash bins

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Prof. Dr. David Vilchez, Spokesperson of the new research group.

A new DFG-funded research group investigates how proteostasis is regulated at the organismal level and its impact on aging and disease.

The German Research Foundation (DFG) has established five new research groups to address pressing scientific questions. This decision was made by the DFG's Main Committee based on the Senate's recommendations. In total, these research groups will receive approximately 19 million euros in funding, including program allowances for indirect project costs. In addition to the new groups, the DFG has also approved extensions for four existing research groups, one clinical research group, and one collegiate research group. Research groups receive funding for up to eight years and play a crucial role in fostering innovative research directions.

One of these newly established research groups focuses on the study of organismal proteostasis. This highly relevant research initiative is coordinated by CECAD Prof. Dr. David Vilchez and Prof. Dr. Thorsten Hoppe (University of Cologne).

Proteostasis is a crucial mechanism for maintaining cellular function by ensuring that proteins are properly folded, regulated, and degraded. Disruptions in this process can lead to severe conditions such as metabolic disorders, cancer, and neurodegenerative diseases. The research group aims to decipher how proteostasis is regulated at the organismal level through interactions between different tissues and how it responds to environmental and metabolic changes.

The approval of this research group highlights the importance of proteostasis research at the CECAD Excellence Cluster of the University of Cologne. CECAD is proud that its scientists are part of this pioneering initiative, contributing significantly to the understanding of fundamental mechanisms of aging and age-related diseases.

 

Scientific contact person:
Prof. Dr. David Vilchez
E-Mail: dvilchez[at]uni-koeln.de
Tel: +49 0221 478 84172

Press and Communications Team:
Dr. Tanio Calabrese
E-Mail: g.calabrese[at]uni-koeln.de
 

Official DFG Press Release:
https://www.dfg.de/de/service/presse/pressemitteilungen/2025/pressemitteilung-nr-06

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