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CECAD community members gather in anticipation of the vaccination event.

CECAD Health Day: Protecting Our Community

15.10.2025 Label People Label 2025 Label TopNews

Keeping CECAD healthy against COVID-19, Flu, and RSV with a vaccination campaign

CxUb is the last unit of the polyubiquitin gene, represented here by a moving train that carries at its end a bright wagon attached to a valuable trolley, which symbolize the C-terminally extended ubiquitin, CxUb in short. The train transitions from a stormy sky, with abnormal/dark mitochondrial-shaped clouds, representing stress, to a sunny sky full of healthy/bright mitochondria, thanks to protection from CxUb. The treasure, golden clock and hourglass are metaphors for the essential functions of CxUb in stress resistance, cellular homeostasis and healthy ageing.

A quiet ally: a ubiquitin precursor promotes stress resistance and longevity

02.10.2025

In response to cellular stress, the protein CxUb is activated to identify damaged proteins, thereby maintaining cellular health.…

In mice, inflammation caused by a deficiency in DNA building blocks leads to hardening of the glomeruli in the kidneys.

Hidden cause of inflammation

25.09.2025 Label 2025 Label News and Calendar Label TopNews Label Prof. Dr. Thomas Langer

Excess RNA building blocks destabilize mitochondrial DNA

Wübben Stiftung Wissenschaft Logo

Two Master Students selected for Wübben Stiftung Wissenschaft Scholarship

18.09.2025 Label 2025 Label Award

Niklas Müller and Kyra Olechnowicz, two outstanding students of the Master’s program “Genetics and Biology of Aging and…

Microbial allies

Microbial allies: Bacteria help fight against cancer

11.09.2025 Label 2025 Label News and Calendar

An international team of scientists have discovered that microbes associated with tumours produce a molecule, which can control…

Electron micrograph of mouse brain SCLC allograft showing a synaptic contact between cancer cell (red) and neuronal terminal (yellow).

Wired to Grow: How Small Cell Lung Cancer Hijacks Neuronal Synapses

11.09.2025 Label News and Calendar Label TopNews Label Dr. Elisa Motori Label Prof. Dr. Matteo Bergami Label Prof. Dr. H. Christian Reinhardt

Researchers reveal that lung cancer cells form direct synapses with neurons to grow and proliferate, opening the door to new…

Carien Niessen

Carien Niessen elected new Vice-Rector for Research at the University of Cologne

08.09.2025 Label Research Group Leaders Label News and Calendar Label University of Cologne Label TopNews Label Prof. Dr. Carien Niessen

The University Election Assembly elected Professor Dr Carien Niessen for the office of Vice-Rector for Research. The cell…

Representative immunofluorescence image illustrating the neuroprotective effect of USP4 knockdown in iPSC-derived motor neurons (green) carrying an ALS-linked mutation. Inhibition of USP4 (EPS8 signaling partner) prevents the neurodegeneration (yellow) normally induced by the ALS mutation.

How aging drives neurodegenerative diseases

03.09.2025 Label 2025 Label News and Calendar Label TopNews Label Prof. Dr. David Vilchez

A University of Cologne research team has identified a direct molecular link between aging and neurodegeneration by investigating…

Dr Gianmaria Liccardi led the study that links the STING protein to the programmed cell death necroptosis.

Inhibiting programmed cell death to treat a rare childhood disease

21.08.2025 Label 2025 Label News and Calendar Label TopNews

A preclinical study at the University of Cologne could open up new treatment options for STING-associated vasculopathy with onset…

Mitochondria (blue) surround Toxoplasma (red) in the cell.

Mitochondria defend cells against infections

14.08.2025 Label 2025 Label News and Calendar Label TopNews

Nutrient competition restricts parasite growth

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