We charge our routine analyses. Graduated charges apply for the different user groups (CECAD members, members of the University of Cologne, external scientists). For inquiries please contact Dr. Susanne Brodesser.

• Urbanczyk S, Baris OR, Hofmann J, Taudte RV, Guegen N, Golombek F, Castiglione K, Meng X, Bozec A, Thomas J, Weckwerth L, Mougiakakos D, Schulz SR, Schuh W, Schlötzer-Schrehardt U, Steinmetz TD, Brodesser S, Wiesner RJ, Mielenz D. (2022) Mitochondrial respiration in B lymphocytes is essential for humoral immunity by controlling the flux of the TCA cycle. Cell Rep 39(10):110912
• Hoyer-Allo KJR, Späth MR, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Brönneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler FC, Grundmann F, Hackl MJ, Schermer B, Brüning J, Benzing T, Burst V, Müller RU. (2022) Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney Int 102(3):560-76
• Manka P, Sydor S, Schänzer-Ocklenburg JM, Brandenburg M, Best J, Vilchez-Vargas R, Link A, Heider D, Brodesser S, Figge A, Jähnert A, Coombes JD, Cubero FJ, Kahraman A, Kim MS, Kälsch J, Kinner S, Faber KN, Moshage H, Gerken G, Syn WK, Canbay A, Bechmann LP. (2022) A Potential Role for Bile Acid Signaling in Celiac Disease-Associated Fatty Liver. Metabolites 12(2):130
• Sebeke LC, Castillo Gómez JD, Heijman E, Rademann P, Simon AC, Ekdawi S, Vlachakis S, Toker D, Mink BL, Schubert-Quecke C, Yeo SY, Schmidt P, Lucas C, Brodesser S, Hossann M, Lindner LH, Grüll H. (2022) Hyperthermia-induced doxorubicin delivery from thermosensitive liposomes via MR-HIFU in a pig model. J Control Release 343:798-812
• Massah A, Neupert S, Brodesser S, Homberg U, Stengl M. (2022) Distribution and daily oscillation of GABA in the circadian system of the cockroach Rhyparobia maderae. J Comp Neurol 530(5):770-91
• Stoffel W, Binczek E, Schmidt-Soltau I, Brodesser S, Wegner I. (2021) High fat / high cholesterol diet does not provoke atherosclerosis in the ω3-and ω6-polyunsaturated fatty acid synthesis-inactivated Δ6-fatty acid desaturase-deficient mouse. Mol Metab 54:101335
• Hoyer-Allo KJR, Späth MR, Hanssen R, Johnsen M, Brodesser S, Kaufmann K, Kiefer K, Koehler FC, Göbel H, Kubacki T, Grundmann F, Schermer B, Brüning J, Benzing T, Burst V, Müller RU. (2021) Modulation of Endocannabinoids by Caloric Restriction Is Conserved in Mice but Is Not Required for Protection from Acute Kidney Injury. Int J Mol Sci 22(11):5485
• Kaspar S, Oertlin C, Szczepanowska K, Kukat A, Senft K, Lucas C, Brodesser S, Hatzoglou M, Larsson O, Topisirovic I, Trifunovic A. (2021) Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR. Sci Adv 7(22):eabf0971
• Figge A, Sydor S, Wenning C, Manka P, Assmuth S, Vilchez-Vargas R, Link A, Jähnert A, Brodesser S, Lucas C, Nevzorova YA, Faber KN, Moshage H, Porsch-Özcürümez M, Gerken G, Cubero FJ, Canbay A, Bechmann LP. (2021) Gender and gut microbiota composition determine hepatic bile acid, metabolic and inflammatory response to a single fast-food meal in healthy adults. Clin Nutr 40(5):2609-19
• Bebber CM, Thomas ES, Stroh J, Chen Z, Androulidaki A, Schmitt A, Höhne MN, Stüker L, de Pádua Alves C, Khonsari A, Dammert MA, Parmaksiz F, Tumbrink HL, Beleggia F, Sos ML, Riemer J, George J, Brodesser S, Thomas RK, Reinhardt HC, von Karstedt S. (2021) Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nat Commun 12(1):2048
• Aravamudhan S, Türk C, Bock T, Keufgens L, Nolte H, Lang F, Krishnan RK, König T, Hammerschmidt P, Schindler N, Brodesser S, Rozsivalova DH, Rugarli E, Trifunovic A, Brüning J, Langer T, Braun T, Krüger M. (2021) Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein. J Mol Cell Cardiol 154:41–59
• Osae EA, Bullock T, Chintapalati M, Brodesser S, Hanlon S, Redfern R, Steven P, Wayne Smith C, Rumbaut RE, Burns AR. (2020) Obese Mice with Dyslipidemia Exhibit Meibomian Gland Hypertrophy and Alterations in Meibum Composition and Aqueous Tear Production. Int J Mol Sci 21(22):8772
• Sydor S, Best J, Messerschmidt I, Manka P, Vilchez-Vargas R, Brodesser S, Lucas C, Wegehaupt A, Wenning C, Aßmuth S, Hohenester S, Link A, Faber KN, Moshage H, Cubero FJ, Friedman SL, Gerken G, Trauner M, Canbay A, Bechmann LP. (2020) Altered microbiota diversity and bile acid signaling in cirrhotic and non-cirrhotic NASH-HCC. Clin Transl Gastroenterol 11(3):e00131
• Tadepalle N, Robers L, Veronese M, Zentis P, Babatz F, Brodesser S, Gruszczyk A, Schauss A, Höning S, Rugarli E. (2020) Microtubule-dependent and independent roles of spastin in lipid droplet dispersion and biogenesis. Life Sci Alliance 3(6):e202000715
• Peters F, Tellkamp F, Brodesser S, Wachsmuth E, Tosetti B, Karow U, Bloch W, Utermoehlen O, Kroenke M, Niessen CM. (2020) Murine Epidermal Ceramide Synthase 4 is a Key Regulator of Skin Barrier Homeostasis. J Invest Dermatol 140(10):1927-37
• Tosetti B, Brodesser S, Brunn A, Deckert M, Blüher M, Doehner W, Anker SD, Wenzel D, Fleischmann B, Pongratz C, Peters F, Utermöhlen O, Krönke M. (2020) A Tissue-specific Screen of Ceramide Expression in Aged Mice Identifies Ceramide Synthases-1 and -5 as Potential Regulators of Fiber Size and Strength in Skeletal Muscle. Aging Cell 19(1):e13049
• Ding X, Willenborg S, Bloch W, Wickström SA, Wagle P, Brodesser S, Roers A, Jais A, Brüning JC, Hall MN, Rüegg MA, Eming SA. (2020) Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation. J Allergy Clin Immunol 145(1):283-300
• Schiffmann LM, Werthenbach JP, Heintges-Kleinhofer F, Seeger JM, Fritsch M, Günther SD, Willenborg S, Brodesser S, Lucas C, Jüngst C, Albert MC, Schorn F, Witt A, Moraes CT, Bruns CJ, Pasparakis M, Krönke M, Eming SA, Coutelle O, Kashkar H. (2020) Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth. Nat Commun 11(1):3653 
• Schütter M, Giavalisco P, Brodesser S, Graef M. (2020) Local fatty acid channeling into phospholipid synthesis drives phagophore expansion during autophagy. Cell 180(1):135-49 
• Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin P, Baraibar MA, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M. (2019) Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy. EMBO J38(1):e99576
• Yu H, Dilbaz S, Coßmann J, Hoang AC, Diedrich V, Herwig A, Harauma A, Hoshi Y, Moriguchi T, Landgraf K, Körner A, Lucas C, Brodesser S, Balogh L, Thuróczy J, Karemore G, Kuefner MS, Park EA, Rapp C, Travers JB, Röszer T. (2019) Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages. J Clin Invest 130:2485-99
• Turpin-Nolan SM, Hammerschmidt P, Chen W, Jais A, Timper K, Awazawa M, Brodesser S, Brüning JC. (2019) CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Rep 26(1):1-10
• Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM. (2019) The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int 95(2):333-49
• Edifizi D, Nolte H, Babu V, Castells-Roca L, Mueller MM, Brodesser S, Krüger M, Schumacher B. (2017) Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans. Cell Rep 20(9):2026-43