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Adam Antebi

• Ludewig AH, Gimond C, Judkins JC, Thornton S, Pulido DC, Micikas RJ, Döring F, Antebi A, Braendle C, Schroeder FC (2017). Larval crowding accelerates C. elegans development and reduces lifespan. PLoS Genet. 2017 Apr 10;13(4):e1006717. doi: 10.1371/journal.pgen.1006717. eCollection 2017 Apr
• Tiku V, Jain C, Raz Y, Nakamura S, Heestand B, Liu W, Späth M, Suchiman H, Eka D, Müller RU, Slagboom PE, Partridge L, Antebi A (2017). Small nucleoli are a cellular hallmark of longevity. Nat Commun. 8: 16083. doi: 10.1038/ncomms16083

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Hisham Bazzi

• Bazzi H, Soroka E, Alcorn HL, Kathryn KV (2017). STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo. Proc Natl Acad Sci U S A. December 19; 114(51):E10928-E10936. doi:10.1073/pnas.1713535114
• Cruz-Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, Van Ljcken WFJ, Grosveld F, Frommolt P, Bazzi H, Rada-Iglesias A (2017). PRC2 facilitates the regulatory topology required for poised enhancer function during pluripotent stem cell differentiation. Cell Stem Cell. May 4;20(5):689-705.e9. doi: 10.1016/j.stem.2017.02.004
• Ju Lee H, Bartsch D, Xiao C, Guerrero S, Ahuja G, Schindler C, Moresco JJ, Yates JR 3rd, Gebauer F, Bazzi H, Dieterich C, Kurian L, Vilchez D (2017). A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells. Nat Commun. 2017 Nov 13;8(1):1456. doi: 10.1038/s41467-017-01744-5

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Thomas Benzing

• Bartram MP, Mishra T, Reintjes N, Fabretti F, Gharbi H, Adam AC, Göbel H, Franke M, Schermer B, Haneder S, Benzing T, Beck BB, Müller RU (2017). Characterization of a splice-site mutation in the tumor suppressor gene FLCN associated with renal cancer. BMC Med Genet. 2017 May 12;18(1):53. doi: 10.1186/s12881-017-0416-5
• Cremaschi L, von Versen R, Benzing T, Wiesener M, Zink N, Milkovich G, Paivanas T, Gallagher M, Thaiss F (2017). Induction therapy with rabbit antithymocyte globulin versus basiliximab after kidney transplantation: a health economic analysis from a German perspective. Transpl Int. 2017 Oct;30(10):1011-1019. doi: 10.1111/tri.12991. Epub 2017 Jul 24
• Ebner K, Dafinger C, Ortiz-Bruechle N, Koerber F, Schermer B, Benzing T, Dötsch J, Zerres K, Weber LT, Beck BB, Liebau MC (2017). Challenges in establishing genotype-phenotype correlations in ARPKD: case report on a toddler with two severe PKHD1 mutations. Pediatr Nephrol. 2017 Jul;32(7):1269-1273. doi: 10.1007/s00467-017-3648-x. Epub 2017 Mar 31
• Franke M, Baeßler B, Vechtel J, Dafinger C, Höhne M, Borgal L, Göbel H, Koerber F, Maintz D, Benzing T, Schermer B, Persigehl T (2017). Magnetic resonance T2 mapping and diffusion-weighted imaging for early detection of cystogenesis and response to therapy in a mouse model of polycystic kidney disease. Kidney Int. 2017 Jul 26. pii: S0085-2538(17)30394-0. doi: 10.1016/j.kint.2017.05.024. [Epub ahead of print]
• Grahammer F, Ramakrishnan SK, Rinschen MM, Larionov AA, Syed M, Khatib H, Roerden M, Sass JO, Helmstaedter M, Osenberg D, Kuhne L, Kretz O, Wanner N, Jouret F, Benzing T, Artunc F, Huber TB, Theilig F (2017). mTOR Regulates Endocytosis and Nutrient Transport in Proximal Tubular Cells. J Am Soc Nephrol. 28: 230–241
• Hagmann H, Mangold N, Rinschen MM, Koenig T, Kunzelmann K, Schermer B, Benzing T, Brinkkoetter PT (2017). Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression. FASEB J. 2017 Sep 6. pii: fj.201700309R. doi: 10.1096/fj.201700309R. [Epub ahead of print]
• Koehler S, Brähler S, Braun F, Hagmann H, Rinschen MM, Späth MR, Höhne M, Wunderlich FT, Schermer B, Benzing T, Brinkkoetter PT(2017). Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes. Kidney Int. 2017 Jun;91(6):1510-1517. doi: 10.1016/j.kint.2016.12.011. Epub 2017 Feb 7
• Kohli P, Höhne M, Jüngst C, Bertsch S, Ebert LK, Schauss AC, Benzing T, Rinschen MM, Schermer B. The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia. EMBO Rep. 2017 Sep;18(9):1521-1535. doi: 10.15252/embr.201643846. Epub 2017 Jul 14
• Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B (2017). YAP-mediated mechanotransduction determines the podocyte's response to damage. Sci Signal. 2017 Apr 11;10(474). pii: eaaf8165. doi: 10.1126/scisignal.aaf8165
• Rinschen MM, Hoppe AK, Grahammer F, Kann M, Völker LA, Schurek EM, Binz J, Höhne M, Demir F, Malisic M, Huber TB, Kurschat C, Kizhakkedathu JN, Schermer B, Huesgen PF, Benzing T (2017). N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton. J Am Soc Nephrol. 2017 Oct;28(10):2867-2878. doi: 10.1681/ASN.2016101119. Epub 2017 Jul 19
• Voskarides K, Stefanou C, Pieri M, Demosthenous P, Felekkis K, Arsali M, Athanasiou Y, Xydakis D, Stylianou K, Daphnis E, Goulielmos G, Loizou P, Savige J, Höhne M, Völker LA, Benzing T, Maxwell PH, Gale DP, Gorski M, Böger C, Kollerits B, Kronenberg F, Paulweber B, Zavros M, Pierides A, Deltas C(2017). A functional variant in NEPH3 gene confers high risk of renal failure in primary hematuric glomerulopathies. Evidence for predisposition to microalbuminuria in the general population. PLoS One. 2017 Mar 23;12(3):e0174274. doi: 10.1371/journal.pone.0174274. eCollection 2017

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Matteo Bergami

• Göbel J, Motori E, Bergami M (2017). Spatiotemporal control of mitochondrial network dynamics in astroglial cells. Biochem Biophys Res Commun. 2017 Jul 1. pii: S0006-291X(17)31322-0. doi: 10.1016/j.bbrc.2017.06.191. [Epub ahead of print]
• Jahn HM, Bergami M (2017). Critical periods regulating the circuit integration of adult-born hippocampal neurons. Cell Tissue Res. 2017 Aug 22. doi: 10.1007/s00441-017-2677-x. [Epub ahead of print]

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Andreas Beyer

• Christodoulou EG, Yang H, Lademann F, Pilarsky C, Beyer A, Schroeder M (2017). Detection of COPB2 as a KRAS synthetic lethal partner through integration of functional genomics screens. Oncotarget.
• Hahn O, Grönke S, Stubbs TM, Ficz G, Hendrich O, Krueger F, Andrews S, Zhang Q, Wakelam MJ, Beyer A, Reik W, Partridge L (2017). Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. Genome Biol. 18:56
• Liu Y, Borel C, Li L, Müller T, Williams EG, Germain P-L, Buljan M, Sajic T, Boersema PJ, Shao W, Faini M, Testa G, Beyer A, Antonarakis SE, Aebersold R(2017). Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells. Nat Commun. Accepted
• Mackmull MT, Klaus B, Heinze I, Chokkalingam M, Beyer A, Russell RB, Ori A, Beck M (2017). Landscape of nuclear transport receptor cargo specificity. Molec. Syst. Biol.
• Seifert M, Beyer A (2017). regNet: An R package for network-based propagation of gene expression alterations. Bioinformatics. Accepted
• Tain LS, Sehlke R, Jain C, Chokkalingam M, Nagarajuna N, Essers P, Rassner M, Grönke S, Froelich J, Dieterich C, Mann M, Alic N, Beyer A, Partridge L (2017). A proteomic atlas of insulin signaling reveals tissue-specific mechanisms of longevity-assurance. Mol Syst Biol. Accepted

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Susanne Brodesser

• Edifizi D, Nolte H, Babu V, Castells-Roca L, Mueller MM, Brodesser S, Krüger M, Schumacher B. (2017) Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans. Cell Rep 20(9):2026-43
• Oteng AB, Bhattacharya A, Brodesser S, Qi L, Tan NS, Kersten S. (2017) Feeding Angptl4-/- mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites. J Lipid Res 58:1100-13

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Jens Brüning

• Awazawa M, Gabel P, Tsaousidou E, Nolte H, Krüger M, Schmitz J, Ackermann PJ, Brandt C, Altmüller J, Motameny S, Wunderlich FT, Kornfeld JW, Blüher M, Brüning JC.A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. (2017) Nat Med. Dec; 23(12):1466-1473
• Braune J, Weyer U, Hobusch C, Mauer J, Brüning JC, Bechmann I, Gericke M (2017). IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity. J Immunol. 2017 Feb 13. pii: 1600476. doi: 10.4049/jimmunol.1600476. Epub  2017 Feb 13
• Dodd GT, Andrews ZB, Simonds SE, Michael NJ, DeVeer M, Brüning JC, Spanswick D, Cowley MA, Tiganis T (2017). A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding. Cell Metab. 2017 Aug 1;26(2):375-393.e7. doi: 10.1016/j.cmet.2017.07.013
• Jais A, Brüning JC (2017). Hypothalamic inflammation in obesity and metabolic disease. J Clin Invest. 2017 Jan 3;127(1):24-32. doi: 10.1172/JCI88878
• Loh K, Zhang L, Brandon A, Wang Q, Begg D, Qi Y, Fu M, Kulkarni R, Teo J, Baldock P, Brüning JC, Cooney G, Neely G, Herzog H (2017). Insulin controls food intake and energy balance via NPY neurons. Mol Metab. 2017 Apr 12;6(6):574-584. doi: 10.1016/j.molmet.2017.03.013. eCollection 2017 Jun
• Paeger L, Pippow A, Hess S, Paehler M, Klein AC, Husch A, Pouzat C, Brüning JC, Kloppenburg P (2017). Energy imbalance alters Ca2+ handling and excitability of POMC neurons. Elife. 2017 Aug 1;6. pii: e25641. doi: 10.7554/eLife.25641
• Riera CE, Tsaousidou E, Halloran J, Follett P, Hahn O, Pereira MMA, Ruud LE, Alber J, Tharp K, Anderson CM, Brönneke H, Hampel B, Filho CDM, Stahl A, Brüning JC, Dillin A (2017). The Sense of Smell Impacts Metabolic Health and Obesity. Cell Metab. 2017 Jul 5;26(1):198-211.e5. doi: 10.1016/j.cmet.2017.06.015
• Ruud J, Steculorum SM, Brüning JC (2017). Neuronal control of peripheral insulin sensitivity and glucose metabolism. Nat Commun. 2017 May 4;8:15259. doi: 10.1038/ncomms15259
• Steculorum SM, Timper K, Engström Ruud L, Evers N, Paeger L, Bremser S, Kloppenburg P, Brüning JC (2017). Inhibition of P2Y6 Signaling in AgRP Neurons Reduces Food Intake and Improves Systemic Insulin Sensitivity in Obesity. Cell Rep. 2017 Feb 14;18(7):1587-1597. doi: 10.1016/j.celrep.2017.01.047
• Theurich S, Tsaousidou E, Hanssen R, Lempradl AM, Mauer J, Timper K, Schilbach K, Folz-Donahue K, Heilinger C, Sexl V, Pospisilik JA, Wunderlich FT, Brüning JC (2017). IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis. Cell Metab. 2017 Jul 5;26(1):171-184.e6. doi: 10.1016/j.cmet.2017.05.018
• Timper K, Brüning JC(2017). Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity. Dis Model Mech. 2017 Jun 1;10(6):679-689. doi: 10.1242/dmm.026609
• Timper K, Denson JL, Steculorum SM, Heilinger C, Engström-Ruud L, Wunderlich CM, Rose-John S, Wunderlich FT, Brüning JC (2017). IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling. Cell Rep. 2017 Apr 11;19(2):267-280. doi: 10.1016/j.celrep.2017.03.043
• Xu E, Pereira MMA, Karakasilioti I, Theurich S, Al-Maarri M, Rappl G, Waisman A, Wunderlich FT, Brüning JC (2017).Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance. Nat Commun. 2017 May 3;8:14803. doi: 10.1038/ncomms14803

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Oliver Cornely

• Bagshaw E, Kuessner D, Posthumus J, Escrig C, Blackney M, Heimann SM, Cornely OA (2017). The cost of treating mucormycosis with isavuconazole compared with standard therapy in the UK. Future Microbiol. 2017 Feb 13. doi: 10.2217/fmb-2016-0231. [Epub ahead of print]
• Bassetti M, Garnacho‐Montero J, Calandra T, Kullberg B, Dimopoulos G, Azoulay E, Chakrabarti A,  Kett D, Leon C, Ostrosky‐Zeichner L, Sanguinetti M, Timsit JF, Richardson MD,  Shorr A, Cornely OA (2017). Intensive care medicine research agenda on invasive fungal infection in critically ill patients. Intensive Care Med. DOI 10.1007/s00134-017-4731-2 
• Berner R, Bogner JR, Cornely OA, de With K, Herold S, Kern WV, Lemmen S, Pletz MW, Ruf B, Salzberger B, Stellbrink HJ, Suttorp N, Ullmann AJ, Fatkenheuer G, Jung N, Cornely OA, Leguay T, Maertens J, Vehreschild M, Anagnostopoulos A, Castagnola C, Verga L, Rieger C, Kondakci M, Harter G, Duarte RF, Allione B, Cordonnier C, Heussel CP, Morrissey CO, Agrawal SG, Donnelly JP, Bresnik M, Hawkins MJ, Garner W, Gokbuget N (2017). Randomized comparison of liposomal amphotericin B versus placebo to prevent invasive mycoses in acute lymphoblastic leukaemia. Infection
• Cornely OA (2017). Isavuconazole: is there a need for a new antifungal? J Antimicrob Chemother. 2017;72(suppl_1):i2-i4
• Cornely OA, Mellinghoff SC (2017). Fever in Cancer Patients. Dtsch Med Wochenschr. 2017;142(13):961-8    
• Cornely OA, Lass-Florl C (2017). Improving outcome of fungal diseases - Guiding experts and patients towards excellence. Mycoses. 2017;60(7):420-5
• Cornely OA,  Leguay T, Maertens J,  Vehreschild MJGT,  Anagnostopoulos A, Castagnola C,  Verga L, Rieger C, Kondakci M,  Härter G,  Duarte RF,  Allione B, Cordonnier C,  Heussel CP, Morrissey CO, Agrawal SG, Donnelly JP,  Bresnik M, Hawkins MJ, Garner W, Gökbuget N (2017). Randomized comparison of liposomal amphotericin B versus placebo to prevent invasive mycoses in acute lymphoblastic leukaemia. J Antimicrob Chemother. doi:10.1093/jac/dkx133 
• Cornely OA, Robertson MN, Haider S, Grigg A, Geddes M, Aoun M, Heinz WJ, Raad I, Schanz U, Meyer RG, Hammond SP, Mullane KM, Ostermann H, Ullmann AJ, Zimmerli S, Van Iersel M, Hepler DA, Waskin H, Kartsonis NA, Maertens J. Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease. J Antimicrob Chemother. 2017;72(12):3501    
• Durán Graeff L, Seidel D, Vehreschild MJ, Hamprecht A, Kindo A, Racil Z, Demeter J, De Hoog S, Aurbach U, Ziegler M, Wisplinghoff H, Cornely OA, FungiScope Group (2017). Invasive infections due to Saprochaete and Geotrichum species: Report of 23 cases from the FungiScope Registry. Mycoses. 2017 Feb 2. doi: 10.1111/myc.12595. [Epub ahead of print]
• Gastine S, Lehrnbecher T, Muller C, Farowski F, Bader P, Ullmann-Moskovits J, Cornely OA, Groll AH, Hempel G (2017). Pharmacokinetic Modelling of Voriconazole to Develop an Alternative Dosing Regimen in Children. Antimicrob Agents Ch. 2017
• Gavino C, Mellinghoff S, Cornely OA (2017). Novel bi-allelic splice mutations in CARD9 causing adult-onset Candida endophthalmitis. Mycoses. 2017
• Hassler A, Lieb A, Seidel D, Cesaro S, Greil J, Klimko N, Khostelidi S, Solopova G, Ogunc D, Durán Graeff L, Cornely OA, Vehreschild MJ, Lehrnbecher T (2017). Disseminated Fusariosis in Immunocompromised Children-Analysis of Recent Cases Identified in the Global Fungiscope Registry. Pediatr Infect Dis J. 2017 Feb;36(2):230-231. doi: 10.1097/INF.0000000000001396
• Hurrass J, Heinzowb B, Aurbach U, Bergmann KC, Bufe A, Buzina W, Cornely OA, Engelhart S, Fischer G, Gabrio T, Heinz W, Herr CEW, Kleine-Tebbe J, Klimek L, Köberle M, Lichtnecker H, Lob-Corzilius T, Merget R, Mülleneisen N, Nowak D, Rabe U, Raulf M, Seidl HP, Steiß JO, Szewszyk R,  Thomas P, Valtanen K, Wiesmüller GA (2017). Medical diagnostics for indoor mold exposure. Int J Hyg Envir Heal. 2016 Nov 29 
• Koehler FC, Cornely OA, Wisplinghoff H, Chang DH, Richter A, Koehler P (2017). Candida reactive T cells for the diagnosis of invasive Candida infection of the lumbar vertebral spine. Mycoses. 2017 Sep 5. doi: 10.1111/myc.12696. [Epub ahead of print]
• Koehler P, Hamprecht A, Bader O, Bekeredjian-Ding I, Buchheidt D, Doelken G, Elias J, Haase G, Hahn-Ast C, Karthaus M, Kekulé A, Keller P, Kiehl M, Krause SW, Krämer C, Neumann S, Rohde H, La Rosée P, Ruhnke M, Schafhausen P, Schalk E, Schulz K, Schwartz S, Silling G, Staib P, Ullmann A, Vergoulidou M, Weber T, Cornely OA, Vehreschild MJ (2017). Epidemiology of invasive aspergillosis and azole resistance in patients with acute leukaemia: the SEPIA Study. Int J Antimicrob Agents. 2017 Feb;49(2):218-223. doi: 10.1016/j.ijantimicag.2016.10.019
• Kontoyiannis DP, Selleslag D, Mullane K, Cornely OA, Hope W, Lortholary O, Croos-Dabrera R, Lademacher C, Engelhardt M, Patterson TF (2017). Impact of unresolved neutropenia in patients with neutropenia and invasive aspergillosis: a post hoc analysis of the SECURE trial. J Antimicrob Chemother. 2017
• Lehmann C, Berner R, Bogner JR, Cornely OA, de With K, Herold S, Kern WV, Lemmen S, Pletz MW,  Ruf B, Salzberger B, Stellbrink HJ, Suttorp N, Ullmann AJ, Fätkenheuer G, Jung N (2017). The “Choosing Wisely” initiative in infectious diseases. Infection. Springer Verlag. DOI 10.1007/s15010-017-0997-0. Epub 2017 March 13
• Mellinghoff SC, Bassetti M, Dorfel D, Hagel S, Lehners N, Plis A, Schalk E, Vena A, Cornely OA (2017). Isavuconazole shortens the QTc interval. J Clin Microbiol. 2017
• Mellinghoff SC, Panse J, Alakel N, Behre G, Bucheidt D, Christopeit M, Hasenkamp J, Kiehl M, Koldehoff M, Krause SW, Lehners N, Von Lilienfeld-Toal M, Löhnert AY, Maschmeyer G, Teschner D, Ullmann A, Penack O, Ruhnke M, Mayer K, Ostermann H, Wolf HH, Cornely OA (2017). Primary prophylaxis of invasive fungal infections in patients with haematological malignancies: 2017 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO). Ann Oncol. Epub ahead of print
• Risslegger B, Zoran T, Lackner M, Aigner M, Sánchez- Reus F, Rezusta A, Chowdhary A, Jaber Taj-Aldeen S, Arendrup MC, Oliveri S, Kontoyiannis DP, Alastruey-Izquierdo A, Lagrou K, Cascio GL, Meis JF,  Buzina W, Farina C, Drogari-Apiranthitou M, Grancini A, Tortorano AM, Willinger B, Hamprecht A,  Johnson E, Klingspor L, Arsic-Arsenijevic V, Cornely OA, Meletiadis J, Prammer W, Tullio V,  Vehreschild JJ, Trovato L,  Lewis RE, Segal E, Rath PM, Hamal P, Rodriguez-Iglesias M, Roilides E, Arikan-Akdagli S,  Chakrabarti A, Colombo AL, Fernández MS, Martin-Gomez MT, Badali H, Petrikkos G, Klimko N, Heimann SM, Houbraken J, Uzun O, Edlinger M, de la Fuente S, Lass-Flörl C (2017). A Prospective International Aspergillus terreus Survey: An EFISG, ISHAM and ECMM Joint Study. Clinical Microbiology and Infection. doi: 10.1016/j.cmi.2017.04.012 
• Salzer HJ, Cornely OA (2017). Awareness of predictors of mortality may help improve outcome in chronic pulmonary aspergillosis. Eur Respir J. 2017 Feb 8;49(2). pii: 1602520. doi: 10.1183/13993003.02520-2016. No abstract available
• Sartelli M, Labricciosa FM, Barbadoro P, Pagani L, Ansaloni L, Brink AJ, Carlet J, Khanna A, Chichom-Mefire A, Coccolini F, Di Saverio S, May AK, Viale P, Watkins RR, Scudeller L, Abbo LM, Abu-Zidan FM, Adesunkanmi AK, Al-Dahir S, Al-Hasan MN, Alis H, Alves C, Araujo da Silva AR, Augustin G, Bala M, Barie PS, Beltran MA, Bhangu A, Bouchra B, Brecher SM, Cainzos MA, Camacho-Ortiz A, Catani M, Chandy SJ, Jusoh AC, Cherry-Bukowiec JR, Chiara O, Colak E, Cornely OA, Cui Y, Demetrashvili Z, De Simone B, De Waele JJ, Dhingra S, Di Marzo F, Dogjani A, Dorj G, Dortet L, Duane TM, Elmangory MM, Enani MA, Ferrada P, Esteban Foianini J, Gachabayov M, Gandhi C, Ghnnam WM, Giamarellou H, Gkiokas G, Gomi H, Goranovic T, Griffiths EA, Guerra Gronerth RI, Haidamus Monteiro JC, Hardcastle TC, Hecker A, Hodonou AM, Ioannidis O, Isik A, Iskandar KA, Kafil HS, Kanj SS, Kaplan LJ, Kapoor G, Karamarkovic AR, Kenig J, Kerschaever I, Khamis F, Khokha V, Kiguba R, Kim HB, Ko WC, Koike K, Kozlovska I, Kumar A, Lagunes L, Latifi R, Lee JG, Lee YR, Leppaniemi A, Li Y, Liang SY, Lowman W, Machain GM, Maegele M, Major P, Malama S, Manzano-Nunez R, Marinis A, Martinez Casas I, Marwah S, Maseda E, McFarlane ME, Memish Z, Mertz D, Mesina C, Mishra SK, Moore EE, Munyika A, Mylonakis E, Napolitano L, Negoi I, Nestorovic MD, Nicolau DP, Omari AH, Ordonez CA, Paiva JA, Pant ND, Parreira JG, Pedziwiatr M, Pereira BM, Ponce-de-Leon A, Poulakou G, Preller J, Pulcini C, Pupelis G, Quiodettis M, Rawson TM, Reis T, Rems M, Rizoli S, Roberts J, Pereira NR, Rodriguez-Bano J, Sakakushev B, Sanders J, Santos N, Sato N, Sawyer RG, Scarpelini S, Scoccia L, Shafiq N, Shelat V, Sifri CD, Siribumrungwong B, Soreide K, Soto R, de Souza HP, Talving P, Trung NT, Tessier JM, Tumbarello M, Ulrych J, Uranues S, Van Goor H, Vereczkei A, Wagenlehner F, Xiao Y, Yuan KC, Wechsler-Fordos A, Zahar JR, Zakrison TL, Zuckerbraun B, Zuidema WP, Catena F (2017). The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardship-results from an international cross-sectional survey. World J Emerg Surg. 2017;12:34
• Seidel D, Duran Graeff LA, Vehreschild MJGT, Wisplinghoff H, Ziegler M, Vehreschild J, Liss B, Hamprecht A, Köhler P, Racil Z, Klimko N, Sheppard DC, Herbrecht R, Chowdhary A, Cornely OA (2017). FungiScope -Global Emerging Fungal Infection Registry. Mycoses. 2017;60(8):508-16
• Solano C, Slavin M, Shaul AJ, Marks DI, Cordonnier C, Cornely OA, Pagliuca A, Cragin L, Jarque I, Garcia-Vidal C, Sorensen S, Vanness DJ, Charbonneau C, Barrueta JA, Peral C, De Salas-Cansado M, Bow EJ (2017). Economic evaluation of azoles as primary prophylaxis for the prevention of invasive fungal infections in Spanish patients undergoing allogeneic haematopoietic stem cell transplant. Mycoses. 2017 Feb;60(2):79-88. doi: 10.1111/myc.12552
• Springer J, White PL, Kessel J, Wieters I, Teschner D, Korczynski D, Liebregts T, Cornely OA, Schwartz S, Elgeti T, Meintker L, Krause SW, Posso RB, Heinz WJ, Fuhrmann S, Vehreschild JJ, Einsele H, Rickerts V, Loeffler J (2017). A Comparison of Aspergillus and Mucorales PCR Testing of Different BAL Fractions from Patients with Suspected Invasive Pulmonary Fungal Disease. J Clin Microbiol. 2017
• Vehreschild JJ, Heussel CP, Groll AH, Vehreschild MJ, Silling G, Würthwein G, Brecht M, Cornely OA (2017). Serial assessment of pulmonary lesion volume by computed tomography allows survival prediction in invasive pulmonary aspergillosis. Eur Radiol. 2017 Jan 12. doi: 10.1007/s00330-016-4717-4. [Epub ahead of print]
• Walther G, Stasch S, Kaerger K, Hamprecht A, Roth M, Cornely OA, Geerling G, Mackenzie CR, Kurzai O, von Lilienfeld-Toal M (2017). Fusarium Keratitis in Germany. J Clin Microbiol. 2017 Jul 26. pii: JCM.00649-17. doi: 10.1128/JCM.00649-17. [Epub ahead of print]
• Wiesmuller GA, Heinzow B, Aurbach U, Bergmann KC, Bufe A, Buzina W, Cornely OA, Engelhart S, Fischer G, Gabrio T, Heinz W, Herr CEW, Kleine-Tebbe J, Klimek L, Koberle M, Lichtnecker H, Lob-Corzilius T, Merget R, Mulleneisen N, Nowak D, Rabe U, Raulf M, Seidl HP, Steiss JO, Szewszyk R, Thomas P, Valtanen K, Hurrass J (2017). Abridged version of the AWMF guideline for the medical clinical diagnostics of indoor mould exposure: S2K Guideline of the German Society of Hygiene, Environmental Medicine and Preventive Medicine GHUP in collaboration with the German Association of Allergists AeDA, the German Society of Dermatology DDG, the German Society for Allergology and Clinical Immunology DGAKI, the German Society for Occupational and Environmental Medicine DGAUM, the German Society for Hospital Hygiene DGKH, the German Society for Pneumology and Respiratory Medicine DGP, the German Mycological Society DMykG, the Society for Pediatric Allergology and Environmental Medicine GPA, the German Federal Association of Pediatric Pneumology BAPP, the Austrian Society for Medical Mycology OGMM. Allergo Journal International. 2017;26(5):168-93
• Wilcox MH, Gerding DN, Poxton IR, Kelly C, Nathan R, Birch T, Cornely OA, Rahav G, Bouza E, Lee C, Jenkin G, Jensen W, Kim YS, Yoshida J, Gabryelski L, Pedley A, Eves K, Tipping R, Guris D, Kartsonis N, Dorr MB, MODIFY I and MODIFY II Investigators (2017). Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection. N Engl J Med. 2017 Jan 26;376(4):305-317. doi: 10.1056/NEJMoa1602615

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Constantinos Demetriades 

• Romero-Pozuelo J, Demetriades C, Schroeder P, Teleman AA (2017). CycD/Cdk4 and discontinuities in Dpp signaling activate TORC1 in the Drosophila wing disc.Dev Cell. 2017 Aug 21;42(4):376-387.e5

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Sabine Eming

• Bukowiecki A, Hos D, Cursiefen C, Eming SA (2017). Wound-Healing Studies in Cornea and Skin: Parallels, Differences and Opportunities. Int J Mol Sci. 2017 Jun 12;18(6). pii: E1257. doi: 10.3390/ijms18061257
• Eming SA, Wynn TA, Martin P (2017). Inflammation and Metabolism in Tissue Repair and Regeneration. Science. In press
• Ghouse SM, Polikarpova A, Muhandes L, Dudeck J, Tantcheva-Poόr I, Hartmann K, Lesche M, Dahl A, Eming SA, Müller W, Behrendt R, Roers A (2017). Although abundant in tumor tissue, mast cells have no effect on immunological micro-milieu or growth of HPV-induced or transplanted tumors. Cell Reports. In press
• Hos D, Bukowiecki A, Horstmann J, Bock F, Bucher F, Heindl LM, Siebelmann S, Steven P, Dana R, Eming SA, Cursiefen C (2017).Transient Ingrowth of Lymphatic Vessels into the Physiologically Avascular Cornea Regulates Corneal Edema and Transparency. Sci Rep. 2017 Aug 3;7(1):7227. doi: 10.1038/s41598-017-07806-4
• Lucas T, Schäfer F, Müller P, Eming SA, Heckel A, Dimmeler S (2017). Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice. Nature Communications. In press 
• Marston WA, Ennis WJ, Lantis JC 2nd, Kirsner RS, Galiano RD, Vanscheidt W, Eming SA, Malka M, Cargill DI, Dickerson JE Jr, Slade HB, HP802-247 Study Group (2017). Baseline factors affecting closure of venous leg ulcers. J Vasc Surg Venous Lymphat Disord. 2017 Nov;5(6):829-835.e1. doi: 10.1016/j.jvsv.2017.06.017
• Nürnberg C, Kociok N, Brockmann C, Lischke T, Crespo-Garcia S, Reichhart N, Wolf S, Baumgrass R, Eming SA, Beer-Hammer S, Joussen AM (2017). Myeloid cells contribute indirectly to VEGF expression upon hypoxia via activation of Müller cells. Exp Eye Res. 2017 Oct 14. pii: S0014-4835(17)30458-X. doi: 10.1016/j.exer.2017.10.011. [Epub ahead of print]

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Christian Frezza

• Braicu EI, Darb-Esfahani S, Schmitt WD, Koistinen KM, Heiskanen L, Pöhö P, Budczies J, Kuhberg M, Dietel M, Frezza C, Denkert C, Sehouli J, Hilvo M (2017). High- grade ovarian serous carcinoma patients exhibit profound alterations in lipid metabolism. Oncotarget. 2017 Oct 26;8(61):102912-102922. doi: 10.18632/oncotarget.22076. PMID: 29262533; PMCID: PMC5732699.
• Gonçalves E, Sciacovelli M, Costa ASH, Tran MGB, Johnson TI, Machado D, Frezza C, Saez-Rodriguez J (2017). Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells. Metab Eng. 2018 Jan;45:149-157. doi: 10.1016/j.ymben.2017.11.011. Epub 2017 Nov 27. PMID: 29191787; PMCID: PMC5805855.
• Tyrakis PA, Yurkovich ME, Sciacovelli M, Papachristou EK, Bridges HR, Gaude E, Schreiner A, D'Santos C, Hirst J, Hernandez-Fernaud J, Springett R, Griffiths JR, Frezza C (2017). Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects. Cell Rep. 2017 Oct 24;21(4):1036-1047. doi: 10.1016/j.celrep.2017.09.092. PMID: 29069586; PMCID: PMC5668630.
• Valcarcel-Jimenez L, Gaude E, Torrano V, Frezza C, Carracedo A (2017). Mitochondrial Metabolism: Yin and Yang for Tumor Progression. Trends Endocrinol Metab. 2017 Oct;28(10):748-757. doi: 10.1016/j.tem.2017.06.004. PMID: 28938972; PMCID: PMC6047739.
• Iraci N, Gaude E, Leonardi T, Costa ASH, Cossetti C, Peruzzotti-Jametti L, Bernstock JD, Saini HK, Gelati M, Vescovi AL, Bastos C, Faria N, Occhipinti LG, Enright AJ, Frezza C*, Pluchino S*. Extracellular vesicles are independent metabolic units with asparaginase activity. Nat Chem Biol. 2017 Sep;13(9):951-955. doi: 10.1038/nchembio.2422. Epub 2017 Jul 3. PMID: 28671681; PMCID: PMC5563455. *: co-last authors
• Amelio I, Melino G, Frezza C (2017). Exploiting tumour addiction with a serine and glycine-free diet. Cell Death Differ. 2017 Aug;24(8):1311-1313. doi: 10.1038/cdd.2017.83. Epub 2017 Jun 2. PMID: 28574507; PMCID: PMC5520463.
• Costa ASH, Frezza C (2017). Metabolic Reprogramming and Oncogenesis: One Hallmark, Many Organelles. Int Rev Cell Mol Biol. 2017;332:213-231. doi: 10.1016/bs.ircmb.2017.01.001. Epub 2017 Mar 15. PMID: 28526133.
• Sciacovelli M, Frezza C (2017). Metabolic reprogramming and epithelial-to- mesenchymal transition in cancer. FEBS J. 2017 Oct;284(19):3132-3144. doi: 10.1111/febs.14090. Epub 2017 May 21. PMID: 28444969; PMCID: PMC6049610.
• Frezza C (2017). Mitochondrial metabolites: undercover signalling molecules. Interface Focus. 2017 Apr 6;7(2):20160100. doi: 10.1098/rsfs.2016.0100. PMID: 28382199; PMCID: PMC5311903.
• Connor TM, Hoer S, Mallett A, Gale DP, Gomez-Duran A, Posse V, Antrobus R, Moreno P, Sciacovelli M, Frezza C, Duff J, Sheerin NS, Sayer JA, Ashcroft M, Wiesener MS, Hudson G, Gustafsson CM, Chinnery PF, Maxwell PH (2017). Mutations in mitochondrial DNA causing tubulointerstitial kidney disease. PLoS Genet. 2017 Mar 7;13(3):e1006620. doi: 10.1371/journal.pgen.1006620. PMID: 28267784; PMCID: PMC5360345.
• Ma EH, Bantug G, Griss T, Condotta S, Johnson RM, Samborska B, Mainolfi N, Suri V, Guak H, Balmer ML, Verway MJ, Raissi TC, Tsui H, Boukhaled G, Henriques da Costa S, Frezza C, Krawczyk CM, Friedman A, Manfredi M, Richer MJ, Hess C, Jones RG (2017). Serine Is an Essential Metabolite for Effector T Cell Expansion. Cell Metab. 2017 Feb 7;25(2):345-357. doi: 10.1016/j.cmet.2016.12.011. Epub 2017 Jan 19. Erratum in: Cell Metab. 2017 Feb 7;25(2):482. PMID: 28111214.
• Zecchini V, Frezza C (2017). Metabolic synthetic lethality in cancer therapy. Biochim Biophys Acta Bioenerg. 2017 Aug;1858(8):723-731. doi: 10.1016/j.bbabio.2016.12.003. Epub 2016 Dec 9. PMID: 27956047.
• Sciacovelli M, Frezza C (2017). Fumarate drives EMT in renal cancer. Cell Death Differ. 2017 Jan;24(1):1-2. doi: 10.1038/cdd.2016.137. Epub 2016 Nov 25. PMID: 27886164; PMCID: PMC5260501.

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Michael Hallek

• Al-Sawaf O, Cramer P, Goede V, Hallek M, Pflug N (2017). Bendamustine and its role in the treatment of unfit patients with chronic lymphocytic leukaemia: a perspective review. Ther Adv Hematol. 2017 Jun;8(6):197-205. doi: 10.1177/2040620717699365. Epub 2017 Mar 30
• Al-Sawaf O, Fischer K, Engelke A, Pflug N, Hallek M, Goede V (2017). Obinutuzumab in chronic lymphocytic leukemia: design, development and place in therapy. Drug Des Devel Ther. 2017 Jan 25;11:295-304. doi: 10.2147/DDDT.S104869. eCollection 2017
• Al-Sawaf O, Robrecht S, Bahlo J, Fink AM, Cramer P, von Tresckow J, Maurer C, Bergmann M, Seiler T, Lange E, Kneba M, Stilgenbauer S, Döhner H, Kiehl MG, Jäger U, Wendtner CM, Fischer K, Goede V, Hallek M, Eichhorst B, Hopfinger G (2017). Impact of gender on outcome after chemoimmunotherapy in patients with chronic lymphocytic leukemia: a meta-analysis by the German CLL study group. Leukemia. 2017 Oct;31(10):2251-2253. doi: 10.1038/leu.2017.221. Epub 2017 Jul 12
• Edelmann J, Tausch E, Landau DA, Robrecht S, Bahlo J, Fischer K, Fink AM, Bloehdorn J, Holzmann K, Böttcher S, Werner L, Kneba M, Gribben JG, Neuberg DS, Wu CJ, Hallek M, Döhner H, Stilgenbauer S (2017). Frequent evolution of copy number alterations in CLL following first-line treatment with FC(R) is enriched with TP53 alterations: results from the CLL8 trial. Leukemia. 2017 Mar;31(3):734-738. doi: 10.1038/leu.2016.317. Epub 2016 Nov 2
• Eichhorst B, Hallek M (2017). Erratum to: Chronic lymphocytic leukemia. Treatment concepts in transition. Internist (Berl). 2017 Aug 18. doi: 10.1007/s00108-017-0312-2. [Epub ahead of print]
• Eichhorst B, Hallek M (2017). Prognostication of chronic lymphocytic leukemia in the era of new agents. Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):149-155
• Fink AM, Bahlo J, Robrecht S, Al-Sawaf O, Aldaoud A, Hebart H, Jentsch-Ullrich K, Dörfel S, Fischer K, Wendtner CM, Nösslinger T, Ghia P, Bosch F, Kater AP, Döhner H, Kneba M, Kreuzer KA, Tausch E, Stilgenbauer S, Ritgen M, Böttcher S, Eichhorst B, Hallek M (2017). Lenalidomide maintenance after first-line therapy for high-risk chronic lymphocytic leukaemia (CLLM1): final results from a randomised, double-blind, phase 3 study. Lancet Haematol. 2017 Oct;4(10):e475-e486. doi: 10.1016/S2352-3026(17)30171-0. Epub 2017 Sep 12
• Fischer K, Al-Sawaf O, Fink AM, Dixon M, Bahlo J, Warburton S, Kipps TJ, Weinkove R, Robinson S, Seiler T, Opat S, Owen C, López J, Humphrey K, Humerickhouse R, Tausch E, Frenzel L, Eichhorst B, Wendtner CM, Stilgenbauer S, Langerak AW, van Dongen JJM, Böttcher S, Ritgen M, Goede V, Mobasher M, Hallek M (2017). Venetoclax and obinutuzumab in chronic lymphocytic leukemia. Blood. 2017 May 11;129(19):2702-2705. doi: 10.1182/blood-2017-01-761973. Epub 2017 Mar 21
• Fölsch UR, Hallek M, Raupach T, Hasenfuß G (2017). Response to and further development of the Choosing wisely initiative. Internist (Berl). 2017 Jun;58(6):527-531. doi: 10.1007/s00108-017-0246-8
• Göckeritz E, Vondey V, Guastafierro A, Pizevska M, Hassenrück F, Neumann L, Hallek M, Krause G (2017). Establishing a chemical genetic link between Bruton tyrosine kinase activity in malignant B cells and cell functions involved in the micro-environmental dialogue. Br J Haematol. 2017 Sep;178(6):949-953. doi: 10.1111/bjh.14781. Epub 2017 Jun 1
• Gruell H, Hamacher L, Jennissen V, Tuchscherer A, Ostendorf N, Löffler T, Hallek M, Kochanek M, Tannich E, Böll B, Fätkenheuer G (2017). On Taking a Different Route: An Unlikely Case of Malaria by Nosocomial Transmission. Clin Infect Dis. 2017 Oct 15;65(8):1404-1406. doi: 10.1093/cid/cix520
• Hahn M, Bürckert JP, Luttenberger CA, Klebow S, Hess M, Al-Maarri M, Vogt M, Reißig S, Hallek M, Wienecke-Baldacchino A, Buch T, Muller CP, Pallasch CP, Wunderlich FT, Waisman A, Hövelmeyer N (2017). Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-κB signaling. Leukemia. 2017 Jun 1. doi: 10.1038/leu.2017.168. [Epub ahead of print]
• Hallek M (2017). Chronic lymphocytic leukemia: 2017 update on diagnosis, risk stratification, and treatment. Am J Hematol. 2017 Sep;92(9):946-965. doi: 10.1002/ajh.24826
• Hallek M (2017). Role and timing of new drugs in CLL. Hematol Oncol. 2017 Jun;35 Suppl 1:30-32. doi: 10.1002/hon.2397
• Hasenfuß G, Märker-Hermann E, Hallek M, Sieber CC, Fölsch UR (2017). Choosing Wisely-evidence-based. Internist (Berl). 2017 Jun;58(6):525-526. doi: 10.1007/s00108-017-0253-9
• Hoechstetter MA, Busch R, Eichhorst B, Bühler A, Winkler D, Eckart MJ, Vehling-Kaiser U, Schimke H, Jäger U, Hurtz HJ, Hopfinger G, Hartmann F, Fuss H, Abenhardt W, Blau I, Freier W, Müller L, Goebeler M, Wendtner CM, Bahlo J, Fischer K, Bentz M, Emmerich B, Döhner H, Hallek M, Stilgenbauer S (2017). Early, risk-adapted treatment with fludarabine in Binet stage A chronic lymphocytic leukemia patients: results of the CLL1 trial of the German CLL study group. Leukemia. 2017 Aug 14. doi: 10.1038/leu.2017.246. [Epub ahead of print]
• Holtick U, Herling M, Pflug N, Chakupurakal G, Leitzke S, Wolf D, Hallek M, Scheid C, Chemnitz JM (2017). Similar outcome after allogeneic stem cell transplantation with a modified FLAMSA conditioning protocol substituting 4 Gy TBI with treosulfan in an elderly population with high-risk AML. Ann Hematol. 2017 Mar;96(3):479-487. doi: 10.1007/s00277-016-2887-4
• Jawhar M, Naumann N, Knut M, Score J, Ghazzawi M, Schneider B, Kreuzer KA, Hallek M, Drexler HG, Chacko J, Wallis L, Fabarius A, Metzgeroth G, Hofmann WK, Chase A, Tapper W, Reiter A, Cross NCP (2017). Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with eosinophilia. Leukemia. 2017 Oct;31(10):2271-2273. doi: 10.1038/leu.2017.240. Epub 2017 Jul 28
• Jerkeman M, Hallek M, Dreyling M, Thieblemont C, Kimby E, Staudt L (2017). Targeting of B-cell receptor signalling in B-cell malignancies. J Intern Med. 2017 Mar 14. doi: 10.1111/joim.12600. [Epub ahead of print]
• Klymenko T, Bloehdorn J, Bahlo J, Robrecht S, Akylzhanova G, Cox K, Estenfelder S, Wang J, Edelmann J, Strefford JC, Wojdacz TK, Fischer K, Hallek M, Stilgenbauer S, Cragg M, Gribben J, Braun A (2017). Lamin B1 regulates somatic mutations and progression of B-cell malignancies. Leukemia. 2017 Aug 14. doi: 10.1038/leu.2017.255. [Epub ahead of print]
• Knittel G, Rehkämper T, Korovkina D, Liedgens P, Fritz C, Torgovnick A, Al-Baldawi Y, Al-Maarri M, Cun Y, Fedorchenko O, Riabinska A, Beleggia F, Nguyen PH, Wunderlich FT, Ortmann M, Montesinos-Rongen M, Tausch E, Stilgenbauer S, Frenzel LP, Herling M, Herling C, Bahlo J, Hallek M, Peifer M, Buettner R, Persigehl T, Reinhardt HC (2017). Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nat Commun. 2017 Jul 28;8(1):153. doi: 10.1038/s41467-017-00210-6
• Krämer I, Stilgenbauer S, Dietrich S, Böttcher S, Zeis M, Stadler M, Bittenbring J, Uharek L, Scheid C, Hegenbart U, Ho A, Hallek M, Kneba M, Schmitz N, Döhner H, Dreger P (2017). Allogeneic hematopoietic cell transplantation for high-risk CLL: 10-year follow-up of the GCLLSG CLL3X trial. Blood. 2017 Sep 21;130(12):1477-1480. doi: 10.1182/blood-2017-04-775841. Epub 2017 Jul 17
• Krause SW, Oldenburg M, Hallek M, Neubauer A (2017).Priorities of German Oncologists. Results of the "choosing wisely" survey of the German Society of Hematology and Medical Oncology (DGHO). Dtsch Med Wochenschr. 2017 Sep;142(18):e124-e130. doi: 10.1055/s-0043-109525. Epub 2017 Sep 8
• Kron F, Kostenko A, Scheffler M, Müller D, Glossmann JP, Fischer R, Michels S, Nogova L, Hallek M, Zander T, Wolf J (2017). Economic burden of clinical trials in lung cancer in a German Comprehensive Cancer Center. Lung Cancer. 2017 Jun;108:134-139. doi: 10.1016/j.lungcan.2017.03.018. Epub 2017 Mar 30
• Lehmann C, Kochanek M, Abdulla D, Becker S, Böll B, Bunte A, Cadar D, Dormann A, Eickmann M, Emmerich P, Feldt T, Frank C, Fries J, Gabriel M, Goetsch U, Gottschalk R, Günther S, Hallek M, Häussinger D, Herzog C, Jensen B, Kolibay F, Krakau M, Langebartels G, Rieger T, Schaade L, Schmidt-Chanasit J, Schömig E, Schüttfort G, Shimabukuro-Vornhagen A, von Bergwelt-Baildon M, Wieland U, Wiesmüller G, Wolf T, Fätkenheuer G (2017). Control measures following a case of imported Lassa fever from Togo, North Rhine Westphalia, Germany, 2016. Euro Surveill. 2017 Sep;22(39). doi: 10.2807/1560-7917.ES.2017.22.39.17-00088
• Ortmann O, Rösler W, Helbig U; participants of the ERTM (2017). Current developments in cancer care: including the patients' perspective-3rd European Roundtable Meeting (ERTM) June 17, 2016, Berlin, Germany. J Cancer Res Clin Oncol. 2017 Apr;143(4):673-676. doi: 10.1007/s00432-016-2320-3. Epub 2016 Dec 17
• Rawstron AC, Kreuzer KA, Soosapilla A, Spacek M, Stehlikova O, Gambell P, McIver-Brown N, Villamor N, Psarra K, Arroz M, Milani R, de la Serna J, Cedena MT, Jaksic O, Nomdedeu J, Moreno C, Rigolin GM, Cuneo A, Johansen P, Johnsen HE, Rosenquist R, Niemann CU, Kern W, Westerman D, Trneny M, Mulligan S, Doubek M, Pospisilova S, Hillmen P, Oscier D, Hallek M, Ghia P Montserrat E (2017). Reproducible diagnosis of Chronic Lymphocytic Leukemia by flow cytometry: an European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) harmonisation project. Cytometry B Clin Cytom. 2017 Oct 10. doi: 10.1002/cyto.b.21595. [Epub ahead of print]
• Robak T, Hellmann A, Kloczko J, Loscertales J, Lech-Maranda E, Pagel JM, Mato A, Byrd JC, Awan FT, Hebart H, Garcia-Marco JA, Hill BT, Hallek M, Eisenfeld AJ, Stromatt SC, Jaeger U (2017). Randomized phase 2 study of otlertuzumab and bendamustine versus bendamustine in patients with relapsed chronic lymphocytic leukaemia. Br J Haematol. 2017 Feb;176(4):618-628. doi: 10.1111/bjh.14464. Epub 2016 Dec 15
• Schiffmann LM, Brunold M, Liwschitz M, Goede V, Loges S, Wroblewski M, Quaas A, Alakus H, Stippel D, Bruns CJ, Hallek M, Kashkar H, Hacker UT, Coutelle O (2017). A combination of low-dose bevacizumab and imatinib enhances vascular normalisation without inducing extracellular matrix deposition. Br J Cancer. 2017 Feb 28;116(5):600-608. doi: 10.1038/bjc.2017.13. Epub 2017 Jan 31
• Tiao G, Improgo MR, Kasar S, Poh W, Kamburov A, Landau DA, Tausch E, Taylor-Weiner A, Cibulskis C, Bahl S, Fernandes SM, Hoang K, Rheinbay E, Kim HT, Bahlo J, Robrecht S, Fischer K, Hallek M, Gabriel S, Lander ES, Stilgenbauer S, Wu CJ, Kiezun A, Getz G, Brown JR (2017). Rare germline variants in ATM are associated with chronic lymphocytic leukemia. Leukemia. 2017 Oct;31(10):2244-2247. doi: 10.1038/leu.2017.201. Epub 2017 Jun 27
• Wennhold K, Thelen M, Schlößer HA, Haustein N, Reuter S, Garcia-Marquez M, Lechner A, Kobold S, Rataj F, Utermöhlen O, Chakupurakal G, Theurich S, Hallek M, Abken H, Shimabukuro-Vornhagen A, von Bergwelt-Baildon M (2017). Using Antigen-Specific B Cells to Combine Antibody and T Cell-Based Cancer Immunotherapy. Cancer Immunol Res. 2017 Sep;5(9):730-743. doi: 10.1158/2326-6066.CIR-16-0236. Epub 2017 Aug 4
• Wolf C, Garding A, Filarsky K, Bahlo J, Robrecht S, Becker N, Zucknick M, Rouhi A, Weigel A, Claus R, Weichenhan D, Eichhorst B, Fischer K, Hallek M, Kuchenbauer F, Plass C, Döhner H, Stilgenbauer S, Lichter P, Mertens D (2017). NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib. Int J Cancer. 2017 Sep 18. doi: 10.1002/ijc.31057. [Epub ahead of print]
• Xochelli A, Baliakas P, Kavakiotis I, Agathangelidis A, Sutton LA, Minga E, Ntoufa S, Tausch E, Yan XJ, Shanafelt T, Plevova K, Boudjogra M, Rossi D, Davis Z, Navarro A, Sandberg Y, Vojdeman FJ, Scarfo L, Stavroyianni N, Sudarikov A, Veronese S, Tzenou T, Karan-Djurasevic T, Catherwood M, Kienle D, Chatzouli M, Facco M, Bahlo J, Pott C, Pedersen LB, Mansouri L, Smedby KE, Chu CC, Giudicelli V, Lefranc MP, Panagiotidis P, Juliusson G, Anagnostopoulos A, Vlahavas I, Antic D, Trentin L, Montillo M, Niemann C, Döhner H, Langerak AW, Pospisilova S, Hallek M, Campo E, Chiorazzi N, Maglaveras N, Oscier D, Gaidano G, Jelinek DF, Stilgenbauer S, Chouvarda I, Darzentas N, Belessi C, Davi F, Hadzidimitriou A, Rosenquist R, Ghia P, Stamatopoulos K (2017). Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes. Clin Cancer Res. 2017 Sep 1;23(17):5292-5301. doi: 10.1158/1078-0432.CCR-16-3100. Epub 2017 May 23

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Matthias Hammerschmidt

• Lessel D, Wu D, Trujillo C, Ramezani T, Lessel I, Alwasiyah MK, Saha B, Hisama FM, Rading K, Goebel I, Schütz P, Speit G, Högel J, Thiele H, Nürnberg G, Nürnberg P, Hammerschmidt M, Zhu Y, Tong DR, Katz C, Martin GM, Oshima J, Prives C, Kubisch C (2017). Dysfunction of the MDM2/p53 axis is linked to premature aging. J Clin Invest. 2017 Oct 2;127(10):3598-3608. doi: 10.1172/JCI92171. Epub 2017 Aug 28
• Riessland M, Kaczmarek A, Schneider S, Swoboda KJ, Löhr H, Bradler C, Grysko V, Dimitriadi M, Hosseinibarkooie S, Torres-Benito L, Peters M, Upadhyay A, Biglari N, Kröber S, Hölker I, Garbes L, Gilissen C, Hoischen A, Nürnberg G, Nürnberg P, Walter M, Rigo F, Bennett CF, Kye MJ, Hart AC, Hammerschmidt M, Kloppenburg P, Wirth B (2017). Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. Am J Hum Genet. 2017 Feb 2;100(2):297-315. doi: 10.1016/j.ajhg.2017.01.005

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Hans-Christian Hennies

• Ammann S, Lehmberg K, Zur Stadt U, Klemann C, Bode SFN, Speckmann C, Janka G, Wustrau K, Rakhmanov M, Fuchs I, Hennies HC, Ehl S; HLH study of the GPOH (2017). Effective Immunological Guidance of Genetic Analyses Including Exome Sequencing in Patients Evaluated for Hemophagocytic Lymphohistiocytosis.J Clin Immunol. 2017 Nov;37(8):770-780. doi: 10.1007/s10875-017-0443-1. Epub 2017 Sep 21
• Ng M, Thakkar D, Southam L, Werker P, Ophoff R, Becker K, Nothnagel M, Franke A, Nürnberg P, Espirito-Santo AI, Izadi D, Hennies HC, Nanchahal J, Zeggini E, Furniss D (2017). A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis.Am J Hum Genet. 2017 Sep 7;101(3):417-427. doi: 10.1016/j.ajhg.2017.08.006
• Oji V, Preil ML, Kleinow B, Wehr G, Fischer J, Hennies HC, Hausser I, Breitkreutz D, Aufenvenne K, Stieler K, Tantcheva-Poór I, Weidinger S, Emmert S, Hamm H, Perusquia-Ortiz AM, Zaraeva I, Diem A, Giehl K, Fölster-Holst R, Kiekbusch K, Höger P, Ott H, Traupe H (2017). S1 guidelines for the diagnosis and treatment of ichthyoses - update.J Dtsch Dermatol Ges. 2017 Oct;15(10):1053-1065. doi: 10.1111/ddg.13340

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Marco Herling

• Andersson EI, Pützer S, Yadav B, Dufva O, Khan S, He L, Sellner L, Schrader A, Crispatzu G, Oleś M, Zhang H, Adnan-Awad S, Lagström S, Bellanger D, Mpindi JP, Eldfors S, Pemovska T, Pietarinen P, Lauhio A, Tomska K, Cuesta-Mateos C, Faber E, Koschmieder S, Brümmendorf TH, Kytölä S, Savolainen ER, Siitonen T, Ellonen P, Kallioniemi O, Wennerberg K, Ding W, Stern MH, Huber W, Anders S, Tang J, Aittokallio T, Zenz T, Herling M, Mustjoki S (2017). Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling. Leukemia. 2017 Aug 14. doi: 10.1038/leu.2017.252. [Epub ahead of print]
• Böll B, Dickerhoff R, Herling M (2017). Blut und blutbildende Organe. In: Braun und Müller-Wieland, eds., Basislehrbuch Innere Medizin. 6^th edition 2017, Elsevier / Urban & Fischer (in press)
• Coppe A, Andersson EI, Binatti A, Gasparini VR, Bortoluzzi S, Clemente M, Herling M, Maciejewski J, Mustjoki S, Bortoluzzi S (2017). Genomic landscape characterization of large granular lymphocyte leukemia with a systems genetics approach. Leukemia. 2017 Feb 7. doi: 10.1038/leu.2017.49. [Epub ahead of print]
• Crispatzu G, Kulkarni P, Toliat MR, Nürnberg P, Herling M, Herling CD, Frommolt P (2017). Semi-automated cancer genome analysis using high-performance computing. Hum Mutat. 2017 Oct;38(10):1325-1335. doi: 10.1002/humu.23275. Epub 2017 Jul 17
• Gilles R, Herling M, Holtick U, Heger E, Awerkiew S, Fish I, Höller K, Sierra S, Knops E, Kaiser R, Scheid C, Di Cristanziano V (2017). Dynamics of Torque Teno virus viremia could predict risk of complications after allogeneic hematopoietic stem cell transplantation. Med Microbiol Immunol. 2017 Jul 12. doi: 10.1007/s00430-017-0511-4. [Epub ahead of print]
• HerlingM, RengstlB, ScholtysikR, HartmannS, KüppersR, HansmannML, DiebnerH, RoederI, AbkenH, NewrzelaS, KirbergJ (2017). Concepts in mature T-cell lymphomas - highlights from an international joint symposium on T-cell immunology and oncology.Leuk Lymphoma. 2017 Apr;58(4):788-796
• Holtick U, HerlingM, PflugN, ChakupurakalG, LeitzkeS, WolfD, HallekM, ScheidC, Chemnitz J (2017).Similar outcome after allogeneic stem cell transplantation with a modified FLAMSA conditioning protocol substituting 4 Gy TBI with treosulfan in an elderly population with high-risk AML. Ann Hematol. 2017 Mar;96(3):479-487
• Höller K, Fabeni L, Herling M, Holtick U, Scheid C, Knops E, Lübke N, Kaiser R, Pfister H, Di Cristanziano V (2017). Dynamics of BKPyV reactivation and risk of hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. Eur J Haematol. 2017 Aug;99(2):133-140. doi: 10.1111/ejh.12895. Epub 2017 May 30
• Knittel G, Rehkämper T, Korovkina D, Liedgens P, Fritz C, Torgovnick A, Al-Baldawi Y, Al-Maarri M, Cun Y, Fedorchenko O, Riabinska A, Beleggia F, Nguyen PH, Wunderlich FT, Ortmann M, Montesinos-Rongen M, Tausch E, Stilgenbauer S, P Frenzel L, Herling M, Herling C, Bahlo J, Hallek M, Peifer M, Buettner R, Persigehl T, Reinhardt HC (2017). Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nat Commun. 2017 Jul 28;8(1):153. doi: 10.1038/s41467-017-00210-6
• Lohman G, Schumacher B, Herling M (2017). Nucleotide excision repair as a targetable vulnerability in leukemia. Oncotarget 2017; 8:114420-114421; IF 2016/17: 5.168
• Rengstl B, Kim S, Döring C, Weiser C, Bein J, Bankov K, Herling M, Newrzela S, Hansmann ML, Hartmann S (2017). Small and big Hodgkin-Reed-Sternberg cells of Hodgkin lymphoma cell lines L-428 and L-1236 lack consistent differences in gene expression profiles and are capable to reconstitute each other. PLoS One. 2017 May 15;12(5):e0177378. doi: 10.1371/journal.pone.0177378. eCollection 2017
• Shimabukuro-Vornhagen A, García-Márquez M, Fischer RN, Iltgen-Breburda J, Fiedler A, Wennhold K, Rappl G, Abken H, Lehmann C, Herling M, Wolf D, Fätkenheuer G, Rubbert-Roth A, Hallek M, Theurich S, von Bergwelt-Baildon M (2017). Antigen-presenting human B cells are expanded in inflammatory conditions. J Leukoc Biol. 2017 Feb;101(2):577-587
• Tur MK, Daramola AK, Gattenlöhner S, Herling M, Chetty S, Barth S (2017). Restoration of DAP Kinase Tumor Suppressor Function: A Therapeutic Strategy to Selectively Induce Apoptosis in Cancer Cells Using Immunokinase Fusion Proteins. Biomedicines. 2017 Oct 4;5(4). pii: E59. doi: 10.3390/biomedicines5040059. Review

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Jan H.J. Hoeijmakers

• Nonnekens J, Hoeijmakers JH. After surviving cancer, what about late life effects of the cure? EMBO Mol Med. 2017 Jan;9(1):4-6. doi: 10.15252/emmm.201607062. PMID: 27852619

• Jongbloed F, Saat TC, Verweij M, Payan-Gomez C, Hoeijmakers JH, van den Engel S, van Oostrom CT, Ambagtsheer G, Imholz S, Pennings JL, van Steeg H, IJzermans JN, Dollé ME, de Bruin RW. A signature of renal stress resistance induced by short-term dietary restriction, fasting, and protein restriction. Sci Rep. 2017 Jan 19;7:40901. doi: 10.1038/srep40901. PMID: 28102354

• Baar MP, Brandt RM, Putavet DA, Klein JD, Derks KW, Bourgeois BR, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB,  Pothof J, de Bruin RW, Madl T, Hoeijmakers JH, Campisi J, de Keizer PL. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell 169, 132-147 (2017) e16. doi: 10.1016/j.cell.2017.02.031.PMID: 28340339

• van Beek AA, Hugenholtz F, B. Meijer B, B. Sovran B, Perdijk O, Vermeij WP, Brandt RMC, Barnhoorn S, Hoeijmakers JHJ,  de Vos P, Leenen PJM, Hendriks RW,Savelkoul HFJ. Frontline Science: Tryptophan restriction arrests B cell development and enhances microbial diversity in WT and prematurely aging Ercc1(-/Delta 7) mice. J. of Leukocyte Biology 101, 811-821, 2017,  DOI: 10.1189/jlb.1HI0216-062RR

• Ogrodnik M, Miwa S, Tchkonia T, Tiniakos D, Wilson CL, Lahat A, Day CP, Burt A, Palmer A, Anstee QM, Grellscheid SN, Hoeijmakers JHJ, Barnhoorn S, Mann DA, Bird TG, Vermeij WP, Kirkland JL, Passos JF, von Zglinicki T, Jurk D. Cellular senescence drives age-dependent hepatic steatosis. Nature Comm. 8, (June, 13, 2017), Art. Number: 15691, DOI: 10.1038/ncomms15691

• La Fata G, van Vliet N, Barnhoorn S, Brandt RMC, Etheve S, Chenal E, Grunenwald C, Seifert N, Weber P, Hoeijmakers JHJ, Mohajeri MH, Vermeij WP. Vitamin E Supplementation Reduces Cellular Loss in the Brain of a Premature Aging Mouse Model. J Prev Alzheimers Dis. 2017;4(4):226-235. doi: 10.14283/jpad.2017.30.

• Mandemaker IK, van Cuijk L, Janssens RC, Lans H, Bezstarosti K, Hoeijmakers JH, Demmers JA, Vermeulen W, Marteijn JA. DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway. Sci Rep. 2017 Nov 10;7(1):15353. doi: 10.1038/s41598-017-15194-y.

• Theil AF, Mandemaker IK, van den Akker E, Swagemakers SMA, Raams A, Wüst T, Marteijn JA, Giltay JC, Colombijn RM, Moog U, Kotzaeridou U, Ghazvini M, von Lindern M, Hoeijmakers JHJ, Jaspers NGJ, van der Spek PJ, Vermeulen W. Trichothiodystrophy causative TFIIEβ mutation affects transcription in highly differentiated tissue. Hum Mol Genet. 2017 Dec 1;26(23):4689-4698. doi: 10.1093/hmg/ddx351.

• Wu H, van Thiel BS, Bautista-Niño PK, Reiling E, Durik M, Leijten FPJ, Ridwan Y, Brandt RMC, van Steeg H, Dollé MET, Vermeij WP, Hoeijmakers JHJ, Essers J, van der Pluijm I, Danser AHJ, Roks AJM. Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1Δ/- mice. Clin Sci (Lond). 2017 Jul 13;131(15):1941-1953. doi: 10.1042/CS20170026. Print 2017 Aug 1.

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Thorsten Hoppe

• Kevei É, Pokrzywa W, Hoppe T (2017). Repair or destruction-an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasis. FEBS Lett. 591, 2616-35
• Pokrzywa W, Lorenz R, Hoppe T (2017). Chaperone-Directed Ubiquitylation Maintains Proteostasis At the Expense of Longevity. Worm. 6,  e1371403
• Schulz J, Avci D, Queisser MA, Gutschmidt A, Dreher LS, Fenech EJ, Volkmar N, Hayashi Y, Hoppe T, Christianson JC (2017). Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD). J Cell Sci. 130, 3322-35
• Tawo R, Pokrzywa W, Kevei E, Akyuz ME, Balaji V, Arian S, Höhfeld J, Hoppe T (2017). The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover. Cell. 169, 470-82
• Pokrzywa W, Hoppe T (2017). CHIPped balance of proteostasis and longevity. Oncotarget. 57, 96472-3

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Sandra Iden 

• Mescher M, Jeong P, Knapp S, Rübsam M, Saynisch M, Kranen M, Landsberg J, Schlaak M, Mauch C, Tüting T, Niessen CM, Iden S (2017). The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma. J Exp Med. 2017 Jan 17. pii: jem.20160596. doi: 10.1084/jem.20160596. Epub 2017 Jan 17

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Hamid Kashkar

• Hösel M, Quasdorff M, Ringelhan M, Kashkar H, Debey-Pascher S, Sprinzl MF, Bockmann JH, Arzberger S, Webb D, von Olshausen G, Weber A, Schultze JL, Büning H, Heikenwalder M, Protzer U (2017). Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication. Cell Mol Gastroenterol Hepatol. 2017 Jul 19;4(3):339-363. doi: 10.1016/j.jcmgh.2017.07.003. eCollection 2017 Nov
• Saita S, Nolte H, Fiedler K, Kashkar H, Venne S, Zahedi R, Krueger M, Langer M (2017). The rhomboid protease PARL regulates apoptosis via proteolytic maturation of Smac/DIABLO in mitochondria. Nat Cell Biol. In press
• Schiffmann LM, Brunold M, Liwschitz M, Goede V, Hallek M, Kashkar H, Hacker UT, Coutelle O (2017). A combination o 1 f low-dose bevacizumab and imatinib enhances vascular 2 normalisation without inducing extracellular matrix deposition. Br J Cancer. [Epub ahead of print]

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Peter Kloppenburg

• Kumar A, Dejanovic B, Hetsch F, Semtner M, Fusca D, Arjune S, Santamaria-Araujo JA, Winkelmann A, Ayton S, Bush AI, Kloppenburg P, Meier JC, Schwarz G, Belaidi AA (2017).S-sulfocysteine/NMDA receptor-dependentsignaling underlies neurodegeneration in molybdenum cofactor deficiency. J Clin Invest. 2017 Nov 6. pii: 89885. doi: 10.1172/JCI89885. [Epub ahead of print]
• Ortner NJ, Bock G, Dougalis A, Kharitonova M, Duda J, Hess S, Tuluc P, Pomberger T, Stefanova N, Pitterl F, Ciossek T, Oberacher H, Draheim HJ, Kloppenburg P, Liss B, Striessnig J (2017). Lower Affinity of Isradipine for L-Type Ca²⁺ Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson's Disease. J Neurosci. 2017 Jul 12;37(28):6761-6777. doi: 10.1523/JNEUROSCI.2946-16.2017. Epub 2017 Jun 7. PMID: 28592699
• Paeger L, Bardos V, Kloppenburg P (2017). Transient Voltage Activated K⁺ Currents in Central Antennal Lobe Neurons: Cell Type Specific Functional Properties. J Neurophysiol. 2017 Feb 8:jn.00685.2016. doi: 10.1152/jn.00685.2016. [Epub ahead of print]
• Paeger L, Pippow A, Hess S, Paehler M, Klein AC, Husch A, Pouzat C, Brüning JC, Kloppenburg P (2017). Energy imbalance alters Ca²⁺ handling and excitability of POMC neurons. Elife. 2017 Aug 1;6. pii: e25641. doi: 10.7554/eLife.25641. PMID: 28762947
• Paeger L, Karakasilioti I, Altmüller J, Frommolt P, Brüning J, Kloppenburg P (2017). Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin. Elife. 2017 Jun 20;6. pii: e25770. doi: 10.7554/eLife.25770. PMID: 28632132
• Riessland M, Kaczmarek A, Schneider S, Swoboda KJ, Löhr H, Bradler C, Grysko V, Dimitriadi M, Hosseinibarkooie S, Torres-Benito L, Peters M, Upadhyay A, Biglari N, Kröber S, Hölker I, Garbes L, Gilissen C, Hoischen A, Nürnberg G, Nürnberg P, Walter M, Rigo F, Bennett CF, Kye MJ, Hart AC, Hammerschmidt M, Kloppenburg P, Wirth B (2017). Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. Am J Hum Genet. 2017 Feb 2;100(2):297-315. doi: 10.1016/j.ajhg.2017.01.005
• Steculorum SM, Timper K, Engström Ruud L, Evers N, Paeger L, Bremser S, Kloppenburg P, Brüning JC (2017). Inhibition of P2Y6 Signaling in AgRP Neurons Reduces Food Intake and Improves Systemic Insulin Sensitivity in Obesity. Cell Rep. 2017 Feb 14;18(7):1587-1597. doi: 10.1016/j.celrep.2017.01.047

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Natalia Kononenko

• Kononenko NL (2017). Lysosomes convene to keep the synapse clean. J Cell Biol. 2017 Jul 19. pii: jcb.201707070. doi: 10.1083/jcb.201707070. [Epub ahead of print]
• Kononenko NL, Claßen GA, Kuijpers M, Puchkov D, Maritzen T, Tempes A, Malik AR, Skalecka A, Jaworski J, Haucke V (2017). Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration. Nat Commun. 8, 2017
• Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JFA, Horvath TL, Tschöp MH, Heinig M, Trajkovski M, Haucke V, Poy MN (2017). Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nat Neurosci. 2017 Aug;20(8):1096-1103. doi: 10.1038/nn.4590. Epub 2017 Jun 19
• Soykan T, Kaempf N, Vollweiter D, Sakaba T, Goerdeler F, Puchkov D, Kononenko NL, Haucke V (2017). Synaptic vesicle endocytosis occurs on a timescale of seconds and is mediated by formins independent of clathrin. Neuron. 93, 854-866, 2017. IF: 13.9
• Yan X, Kononenko NL, Brüel A, Thomsen JS, Poy MN (2017). Neuronal Cell Adhesion Molecule 1 Regulates Leptin Sensitivity and Bone Mass. Calcif Tissue Int. 2017 Nov 13. doi: 10.1007/s00223-017-0361-5. [Epub ahead of print]

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Tatiana Korotkova

• Ponomarenko A., Korotkova T ( 2017). To eat? To sleep? To run? Coordination of innate behaviours by lateral hypothalamus. Neuroforum. Review. 
• Carus-Cadavieco M, Gorbati M, Ye L, Bender F, van der Veldt S, Kosse C, Börgers C, Lee SY, Ramakrishnan C, Hu Y, Denisova N, Ramm F, Volitaki E, Burdakov D, Deisseroth K, Ponomarenko A, Korotkova T (2017). Gamma oscillations organize top-down signaling to hypothalamus and enable food seeking. Nature. 2017 Feb 9;542(7640):232-236. doi: 10.1038/nature21066. Epub 2017 Feb 1

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Jan-Wilhelm Kornfeld

• Awazawa M, Gabel P, Tsaousidou E, Nolte H, Krüger M, Schmitz J, Ackermann PJ, Brandt C, Altmüller J, Motameny S, Wunderlich FT, Kornfeld JW, Blüher M, Brüning JC (2017). A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. Nat Med. 2017 Nov 6. doi: 10.1038/nm.4420. [Epub ahead of print]

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Thomas Krieg

• Eckes B, Wang F, Moinzadeh P, Hunzelmann N, Krieg T (2017). Pathophysiological Mechanisms in Sclerosing Skin Diseases. Front Med (Lausanne). 2017 Aug 18;4:120. doi: 10.3389/fmed.2017.00120. eCollection 2017. Review
• Knobler R, Moinzadeh P, Hunzelmann N, Kreuter A, Cozzio A, Mouthon L, Cutolo M, Rongioletti F, Denton CP, Rudnicka L, Frasin LA, Smith V, Gabrielli A, Aberer E, Bagot M, Bali G, Bouaziz J, Braae Olesen A, Foeldvari I, Frances C, Jalili A, Just U, Kähäri V, Kárpáti S, Kofoed K, Krasowska D, Olszewska M, Orteu C, Panelius J, Parodi A, Petit A, Quaglino P, Ranki A, Sanchez Schmidt JM, Seneschal J, Skrok A, Sticherling M, Sunderkötter C, Taieb A, Tanew A, Wolf P, Worm M, Wutte NJ, Krieg T(2017). European Dermatology Forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 1: localized scleroderma, systemic sclerosis and overlap syndromes. J Eur Acad Dermatol Venereol. 2017 Sep;31(9):1401-1424. doi: 10.1111/jdv.14458. Epub 2017 Aug 9
• Knobler R, Moinzadeh P, Hunzelmann N, Kreuter A, Cozzio A, Mouthon L, Cutolo M, Rongioletti F, Denton CP, Rudnicka L, Frasin LA, Smith V, Gabrielli A, Aberer E, Bagot M, Bali G, Bouaziz J, Braae Olesen A, Foeldvari I, Frances C, Jalili A, Just U, Kähäri V, Kárpáti S, Kofoed K, Krasowska D, Olszewska M, Orteu C, Panelius J, Parodi A, Petit A, Quaglino P, Ranki A, Sanchez Schmidt JM, Seneschal J, Skrok A, Sticherling M, Sunderkötter C, Taieb A, Tanew A, Wolf P, Worm M, Wutte NJ, Krieg T(2017). European dermatology forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxedema, scleredema and nephrogenic systemic fibrosis. J Eur Acad Dermatol Venereol. 2017 Oct;31(10):1581-1594. doi: 10.1111/jdv.14466. Epub 2017 Aug 8
• Krieg T (2017). How I Became a Clinician Scientist in Dermatology-A Tale of Serendipity, Wise Mentors, and a Good Pinch of Tenacity. J Invest Dermatol. 2017 Jul;137(7):1395-1397. doi: 10.1016/j.jid.2017.05.009. No abstract available
• Schiller HB, Mayr CH, Leuschner G, Strunz M, Staab-Weijnitz C, Preisendörfer S, Eckes B, Moinzadeh P, Krieg T, Schwartz DA, Hatz RA, Behr J, Mann M, Eickelberg O (2017). Deep Proteome Profiling Reveals Common Prevalence of MZB1-Positive Plasma B Cells in Human Lung and Skin Fibrosis. Am J Respir Crit Care Med. 2017 Nov 15;196(10):1298-1310. doi: 10.1164/rccm.201611-2263O

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Martin Krönke

• Blissenbach B, Nakas CT, Krönke M, Geiser T, Merz TM, Pichler Hefti J (2017). Hypoxia-induced changes in plasma microRNAs correlate with pulmonary artery pressure at high altitude. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 28:ajplung.00146.2017. doi: 10.1152/ajplung.00146.2017. [Epub ahead of print]
• Gabriel E, Ramani A, Karow U, Gottardo M, Natarajan K, Gooi LM, Goranci-Buzhala G, Krut O, Peters F, Nikolic M, Kuivanen S, Korhonen E, Smura T, Vapalahti O, Papantonis A, Schmidt-Chanasit J, Riparbelli M, Callaini G, Krönke M, Utermöhlen O, Gopalakrishnan J (2017).  Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids.  Cell Stem Cell. S1934-5909
• Ganesan R, Hos NJ, Gutierrez S, Fischer J, Stepek JM, Daglidu E, Krönke M, Robinson N (2017). Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLoS Pathog. 2017 Feb 13;13(2):e1006227. doi: 10.1371/journal.ppat.1006227. eCollection 2017 Feb
• Hos NJ, Ganesan R, Gutiérrez S, Hos D, Klimek J, Abdullah Z, Krönke M, Robinson N (2017). Type I interferon enhances necroptosis of Salmonella Typhimurium-infected macrophages by impairing antioxidative stress responses. J Cell Biol. 2017 Oct 20. pii: jcb.201701107. doi: 10.1083/jcb.201701107. [Epub ahead of print]

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Marcus Krüger

• Ali T, Krüger M, Bhuju S, Jarek M, Bartkuhn M, Renkawitz R (2017). Chromatin binding of Gcn5 in Drosophila is largely mediated by CP190. Nucleic Acids Res. 2017 Mar 17;45(5):2384-2395. doi: 10.1093/nar/gkw1178
• Awazawa M, Gabel P, Tsaousidou E, Nolte H, Krüger M, Schmitz J, Ackermann PJ, Brandt C, Altmüller J, Motameny S, Wunderlich FT, Kornfeld JW, Blüher M, Brüning JC (2017). A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. Nat Med. 2017 Nov 6. doi: 10.1038/nm.4420. [Epub ahead of print]
• Bicker F, Vasic V, Horta G, Ortega F, Nolte H, Kavyanifar A, Keller S, Stankovic ND, Harter PN, Benedito R, Lutz B, Bäuerle T, Hartwig J, Baumgart J, Krüger M, Radyushkin K, Alberi L, Berninger B, Schmidt MHH (2017). Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception. Nat Commun. 2017 Jun 28;8:15922. doi: 10.1038/ncomms15922
• Bultmann-Mellin I, Dinger K, Debuschewitz C, Loewe KMA, Melcher Y, Plum MTW, Appel S, Rappl G, Willenborg S, Schauss AC, Jüngst C, Krüger M, Dressler S, Nakamura T, Wempe F, Alejandre Alcázar MA, Sterner-Kock A (2017). Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs. Am J Physiol Lung Cell Mol Physiol. 2017 Oct 1;313(4):L687-L698. doi: 10.1152/ajplung.00031.2017. Epub 2017 Jul 6
• Edifizi D, Nolte H, Babu V, Castells-Roca L, Mueller MM, Brodesser S, Krüger M, Schumacher B (2017). Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans. Cell Rep. 2017 Aug 29;20(9):2026-2043. doi: 10.1016/j.celrep.2017.08.028
• Fang J, Ianni A, Smolka C, Vakhrusheva O, Nolte H, Krüger M, Wietelmann A, Simonet NG, Adrian-Segarra JM, Vaquero A, Braun T, Bober E (2017). Sirt7 promotes adipogenesis in the mouse by inhibiting autocatalytic activation of Sirt1. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8352-E8361. doi: 10.1073/pnas.1706945114. Epub 2017 Sep 18
• Gedik N, Krüger M, Thielmann M, Kottenberg E, Skyschally A, Frey UH, Cario E, Peters J, Jakob H, Heusch G, Kleinbongard P (2017). Proteomics/phosphoproteomics of left ventricular biopsies from patients with surgical coronary revascularization and pigs with coronary occlusion/reperfusion: remote ischemic preconditioning. Sci Rep. 2017 Aug 9;7(1):7629. doi: 10.1038/s41598-017-07883-5
• Ianni A, Hoelper S, Krueger M, Braun T, Bober E (2017). Sirt7 stabilizes rDNA heterochromatin through recruitment of DNMT1 and Sirt1. Biochem Biophys Res Commun. 492(3), 434-40
• Lang F, Aravamudhan S, Nolte H, Türk C, Hölper S, Müller S, Günther S, Blaauw B, Braun T, Krüger M (2017). Dynamic changes in the mouse skeletal muscle proteome during denervation-induced atrophy. Dis Model Mech. 2017 Jul 1;10(7):881-896. doi: 10.1242/dmm.028910. Epub 2017 May 25
• Nathan A, Reinhardt P, Kruspe D, Jörß T, Groth M, Nolte H, Habenicht A, Herrmann J, Holschbach V, Toth B, Krüger M, Wang ZQ, Platzer M, Englert C (2017). The Wilms tumor protein Wt1 contributes to female fertility by regulating oviductal proteostasis. Hum Mol Genet. 26(9), 1694-1705.
• Rajman, M., Metge, F., Fiore, R., Khudayberdiev, S., Aksoy-Aksel, A., Bicker, S., Ruedell Reschke, C., Raoof, R., Brennan, G.P., Delanty, N., Farrell, M.A., O'Brien, D.F., Bauer, S., Norwood, B., Veno, M.T., Krüger, M., Braun, T., Kjems, J., Rosenow, F., Henshall, D.C., Dieterich, C., Schratt, G. (2017). A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses. EMBO J. 36(12), 1770-87
• Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B (2017). YAP-mediated mechanotransduction determines the podocyte's response to damage. Sci Signal. 10(474), eaaf8165.
• Saita S, Nolte H, Fiedler KU, Kashkar H, Venne AS, Zahedi RP, Krüger M, Langer T (2017). PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. Nat Cell Biol. 2017 Apr;19(4):318-328. doi: 10.1038/ncb3488. Epub 2017 Mar 13
• Vukotic M, Nolte H, König T, Saita S, Ananjew M, Krüger M, Tatsuta T, Langer T (2017). Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria. Mol Cell. 2017 Aug 3;67(3):471-483.e7. doi: 10.1016/j.molcel.2017.06.013. Epub 2017 Jul 14

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Leo Kurian

• Ju Lee H, Bartsch D, Xiao C, Guerrero S, Ahuja G, Schindler C, Moresco JJ, Yates JR 3rd, Gebauer F, Bazzi H, Dieterich C, Kurian L, Vilchez D (2017). A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells. Nat Commun. 2017 Nov 13;8(1):1456. doi: 10.1038/s41467-017-01744-5
• Palanimurugan R, Gödderz D, Kurian L, Jürgen Dohmen R (2017). Analysis of Cotranslational Polyamine Sensing During Decoding of ODC Antizyme mRNA. Methods Mol Biol. 2018;1694:309-323. doi: 10.1007/978-1-4939-7398-9_26

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Michael Lammers

• Kuhlmann N, Chollet C, Baldus L, Neundorf I, Lammers M (2017). Development of Substrate-Derived Sirtuin Inhibitors with Potential Anticancer Activity. ChemMedChem. Doi: 10.1002/cmdc.201700414. In press
• Yin G, Kistler S, George SD, Kuhlmann N, Garvey L, Huynh M, Bagni RK, Lammers M, Der CJ, Campbell SL (2017). A KRAS GTPase K104Q Mutant Retains Downstream Signaling by Offsetting Defects in Regulation. J Biol Chem. 292, 4446-4456

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Thomas Langer

• Saita S, Nolte H, Fiedler KU, Kashkar H, Venne AS, Zahedi RP, Krüger M, Langer T (2017). The rhomboid protease PARL regulates apoptosis via proteolytic maturation of Smac/DIABLO in mitochondria. Nature Cell Biol. In press
• Tatsuta T, Langer T (2017). Intramitochondrial phospholipid trafficking. Biochim Biophys Acta.1862, 81-89. doi: 10.1016/j.bbalip.2016.08.006

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Nils-Göran Larsson

• Brandt T, Mourier A, Tain LS, Partridge L, Larsson NG, Kühlbrandt W (2017). Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. eLife. 6. 2017 Jul 12;6. pii: e24662. doi: 10.7554/eLife.24662. [Epub ahead of print]
• Jiang M, Kauppila TES, Motori E, Li X, Atanassov I, Folz-Donahue K, Bonekamp NA, Albarran-Gutierrez S, Stewart JB, Larsson NG (2017). Increased Total mtDNA Copy Number Cures Male Infertility Despite Unaltered mtDNA Mutation Load. Cell Metab. 2017 Aug 1;26(2):429-436.e4. doi: 10.1016/j.cmet.2017.07.003
• Kauppila TE, Kauppila JH, Larsson NG (2017). Mammalian Mitochondria and Aging: An Update. Cell Metab. 2017 Jan 10;25(1):57-71
• Kühl I, Miranda M, Atanassov I, Kuznetsova I, Hinze Y, Mourier A, Filipovska A, Larsson NG (2017). Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals. Elife. 2017 Nov 14;6. pii: e30952. doi: 10.7554/eLife.30952. [Epub ahead of print]
• Siira SJ, Spåhr H, Shearwood AJ, Ruzzenente B, Larsson NG, Rackham O, Filipovska A (2017). LRPPRC-mediated folding of the mitochondrial transcriptome. Nat Commun. 2017 Nov 16;8(1):1532. doi: 10.1038/s41467-017-01221-z

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Ivan Matic

• Bonfiglio JJ, Colby T, Matic I (2017). Mass spectrometry for serine ADP-ribosylation? Think o-glycosylation! Nucleic Acids Res. 2017 May 18. doi: 10.1093/nar/gkx446
• Bonfiglio JJ, Fontana P, Zhang Q, Colby T, Gibbs-Seymour I, Atanassov I, Bartlett E, Zaja R, Ahel I, Matic I (2017). Serine ADP-Ribosylation depends on HPF1. Mol Cell. 2017 Mar 2;65(5):932-940.e6. doi: 10.1016/j.molcel.2017.01.003. Epub 2017 Feb 9
• Crawford K, Bonfiglio JJ, Mikoč A, Matic I, Ahel I (2017). Specificity of reversible ADP-ribosylation and regulation of cellular processes. Crit Rev Biochem Mol Biol. 2017 Nov 3:1-19. doi: 10.1080/10409238.2017.1394265. [Epub ahead of print]
• Fontana P, Bonfiglio JJ, Palazzo L, Bartlett E, Matic I, Ahel I (2017). Serine ADP-ribosylation reversal by the hydrolase ARH3. Elife. 2017 Jun 26;6. pii: e28533. doi: 10.7554/eLife.28533
• Zhiteneva A, Bonfiglio JJ, Makarov A, Colby T, Vagnarelli P, Schirmer EC, Matic I, Earnshaw WC (2017). Mitotic post-translational modifications of histones promote chromatin compaction in vitro. Open Biol. 2017 Sep;7(9). pii: 170076. doi: 10.1098/rsob.170076

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Roman-Ulrich Müller

• Bartram MP, Mishra T, Reintjes N, Fabretti F, Gharbi H, Adam AC, Göbel H, Franke M, Schermer B, Haneder S, Benzing T, Beck BB, Müller RU (2017). Characterization of a splice-site mutation in the tumor suppressor gene FLCN associated with renal cancer. BMC Med Genet. 2017 May 12;18(1):53. doi: 10.1186/s12881-017-0416-5
• Müller RU, Haas C, Sayer J (2017). Practical approaches to the management of ADPKD patients in the era of tolvaptan. Clinical Kidney Journal. July 2017 
• Tiku V, Jain C, Raz Y, Nakamura S, Heestand B, Liu W, Späth M, Suchiman HED, Müller RU, Slagboom PE, Partridge L, Antebi A(2017). Small nucleoli are a cellular hallmark of longevity. Nat Commun. 2016 Aug 30;8:16083. doi: 10.1038/ncomms16083          
• Siedek F, Persigehl T, Müller RU, Burst V, Benzing T, Maintz D, Haneder S (2017). Assessing renal changes after remote ischemia preconditioning (RIPC) of the upper extremity using BOLD-imaging at 3T. Magn Reson Mater Phy. (2017)doi:10.1007/s10334-017-0658-4

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Carien Niessen

• Mescher M, Jeong P, Knapp SK, Rübsam M, Saynisch M, Kranen M, Landsberg J, Schlaak M, Mauch C, Tüting T, Niessen CM, Iden S (2017). The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma. J Exp Med. 2017 Feb;214(2):339-358. doi: 10.1084/jem.20160596
• Rübsam M, Broussard JA, Wickström SA, Nekrasova O, Green KJ, Niessen CM (2017). Adherens Junctions and Desmosomes Coordinate Mechanics and Signaling to Orchestrate Tissue Morphogenesis and Function: An Evolutionary Perspective. Cold Spring Harb Perspect Biol. 2017 Sep 11. pii: a029207. doi: 10.1101/cshperspect.a029207. [Epub ahead of print]
• Rübsam M, Mertz AF, Kubo A, Marg S, Jüngst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne E, Moser M, Ziegler W, Amagai M, Wickström SA and Niessen CM (2017). E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and Tight Junction positioning. Nat Commun. 2017 Nov 1;8(1):1250. doi: 10.1038/s41467-017-01170-7
• Wieland D, Brachvogel B, Hornig-Do HT, Neuhaus J, Holzer T, Tobin D, Niessen CM, Wiesner R, Baris O (2017). Imbalance of mitochondrial respiratory chain complexes in the epidermis induces severe skin inflammation. J Invest Derm. 2017 Sep 1. pii: S0022-202X(17)32834-8. doi: 10.1016/j.jid.2017.08.019. [Epub ahead of print]

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Angelika Noegel

• Ahmad I, Baig SM, Abdulkareem AR, Hussain MS, Sur I, Toliat MR, Nürnberg G, Dalibor N, Moawia A, Waseem SS, Asif M, Nagra H, Sher M, Khan MMA, Hassan I, Rehman SU, Thiele H, Altmüller J, Noegel AA, Nürnberg P (2017). Genetic heterogeneity in Pakistani microcephaly families revisited. Clin Genet. Jul;92(1):62-68. doi: 10.1111/cge.12955
• Li P, Stumpf M, Müller R, Eichinger L, Glöckner G, Noegel AA (2017). The function of the inner nuclear envelope protein SUN1 in mRNA export is regulated by phosphorylation. Sci Rep. Aug 22;7(1):9157. doi: 10.1038/s41598-017-08837-7
• Moawia A, Shaheen R, Rasool S, Waseem SS, Ewida N, Budde B, Kawalia A, Motameny S, Khan K, Fatima A, Jameel M, Ullah F, Akram T, Ali Z, Abdullah U, Irshad S, Höhne W, Noegel AA, Al-Owain M, Hörtnagel K, Stöbe P, Baig SM, Nürnberg P, Alkuraya FS, Hahn A, Hussain MS (2017). Mutations of KIF14 cause primary microcephaly by impairing cytokinesis. Ann Neurol. 2017 Oct;82(4):562-577. doi: 10.1002/ana.25044. Epub 2017 Oct 14
• Peche VS, Holak TA, Burgute BD, Kosmas K, Kale SP, Wunderlich FT, Elhamine F, Stehle R, Pfitzer G, Nohroudi K, Addicks K, Stöckigt F, Schrickel JW, Gallinger J, Schleicher M, Noegel AA (2017). Erratum to: Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy. Cell Mol Life Sci. 2017 Nov;74(21):4045. doi: 10.1007/s00018-017-2630-x
• Stumpf M, Müller R, Gaßen B, Wehrstedt R, Fey P, Karow MA, Eichinger L, Glöckner G, Noegel AA (2017). A tripeptidyl peptidase 1 is a binding partner of the Golgi pH regulator (GPHR) in Dictyostelium. Dis Model Mech. Jul 1;10(7):897-907. doi: 10.1242/dmm.029280
• Sukumaran SK, Stumpf M, Salamon S, Ahmad I, Bhattacharya K, Fischer S, Müller R, Altmüller J, Budde B, Thiele H, Tariq M, Malik NA, Nürnberg P, Baig SM, Hussain MS, Noegel AA (2017). CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly. Mol Genet Genomics. Apr;292(2):365-383. doi: 10.1007/s00438-016-1277-x
• Xing X, Mroß C, Hao L, Munck M, Herzog A, Mohr C, Unnikannan CP, Kelkar P, Noegel AA, Eichinger L, Neumann S.Nesprin-2 interacts with Condensin component SMC2. Int J Cell Biol. 2017;2017:8607532. doi: 10.1155/2017/8607532

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Peter Nürnberg

• Ahmad I, Baig SM, Abdulkareem AR, Hussain MS, Sur I, Toliat MR, Nürnberg G, Dalibor N, Moawia A, Waseem SS, Asif M, Nagra H, Sher M, Khan MMA, Hassan I, Rehman SU, Thiele H, Altmüller J, Noegel AA, Nürnberg P (2017). Genetic heterogeneity in Pakistani microcephaly families revisited. Clin Genet. 2017 Jul;92(1):62-68. doi: 10.1111/cge.12955. Epub 2017 Feb 22
• Crispatzu G, Kulkarni P, Toliat MR, Nürnberg P, Herling M, Herling CD, Frommolt P (2017). Semi-automated cancer genome analysis using high-performance computing. Hum Mutat. 2017 Oct;38(10):1325-1335. doi: 10.1002/humu.23275. Epub 2017 Jul 17
• Ehmke N, Graul-Neumann L, Smorag L, Koenig R, Segebrecht L, Magoulas P, Scaglia F, Kilic E, Hennig AF, Adolphs N, Saha N, Fauler B, Kalscheuer VM, Hennig F, Altmüller J, Netzer C, Thiele H, Nürnberg P, Yigit G, Jäger M, Hecht J, Krüger U, Mielke T, Krawitz PM, Horn D, Schuelke M, Mundlos S, Bacino CA, Bonnen PE, Wollnik B, Fischer-Zirnsak B, Kornak U (2017). De Novo Mutations in SLC25A24 Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction. Am J Hum Genet. 2017 Nov 2;101(5):833-843. doi: 10.1016/j.ajhg.2017.09.016
• Gordon CT, Xue S, Yigit G, Filali H, Chen K, Rosin N, Yoshiura KI, Oufadem M, Beck TJ, McGowan R, Magee AC, Altmüller J, Dion C, Thiele H, Gurzau AD, Nürnberg P, Meschede D, Mühlbauer W, Okamoto N, Varghese V, Irving R, Sigaudy S, Williams D, Ahmed SF, Bonnard C, Kong MK, Ratbi I, Fejjal N, Fikri M, Elalaoui SC, Reigstad H, Bole-Feysot C, Nitschké P, Ragge N, Lévy N, Tunçbilek G, Teo AS, Cunningham ML, Sefiani A, Kayserili H, Murphy JM, Chatdokmaiprai C, Hillmer AM, Wattanasirichaigoon D, Lyonnet S, Magdinier F, Javed A, Blewitt ME, Amiel J, Wollnik B, Reversade B (2017). De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development. Nat Genet. 2017 Feb;49(2):249-255. doi: 10.1038/ng.3765. Epub 2017 Jan 9
• Hahnen E, Lederer B, Hauke J, Loibl S, Kröber S, Schneeweiss A, Denkert C, Fasching PA, Blohmer JU, Jackisch C, Paepke S, Gerber B, Kümmel S, Schem C, Neidhardt G, Huober J, Rhiem K, Costa S, Altmüller J, Hanusch C, Thiele H, Müller V, Nürnberg P, Karn T, Nekljudova V, Untch M, von Minckwitz G, Schmutzler RK (2017). Germline Mutation Status, Pathological Complete Response, and Disease-Free Survival in Triple-Negative Breast Cancer: Secondary Analysis of the GeparSixto Randomized Clinical Trial. JAMA Oncol. 2017 Oct 1;3(10):1378-1385. doi: 10.1001/jamaoncol.2017.1007
• Harter P, Hauke J, Heitz F, Reuss A, Kommoss S, Marmé F, Heimbach A, Prieske K, Richters L, Burges A, Neidhardt G, de Gregorio N, El-Balat A, Hilpert F, Meier W, Kimmig R, Kast K, Sehouli J, Baumann K, Jackisch C, Park-Simon TW, Hanker L, Kröber S, Pfisterer J, Gevensleben H, Schnelzer A, Dietrich D, Neunhöffer T, Krockenberger M, Brucker SY, Nürnberg P, Thiele H, Altmüller J, Lamla J, Elser G, du Bois A, Hahnen E, Schmutzler R (2017). Prevalence of deleterious germline variants in risk genes including BRCA1/2 in consecutive ovarian cancer patients (AGO-TR-1). PLoS One. 2017 Oct 20;12(10):e0186043. doi: 10.1371/journal.pone.0186043. eCollection 2017
• Hartz A, Pagel J, Humberg A, Preuss M, Schreiter L, Rupp J, Figge J, Karsten CM, Nürnberg P, Herting E, Göpel W, Härtel C; German Neonatal Network (2017). The association of mannose-binding lectin 2 polymorphisms with outcome in very low birth weight infants. PLoS One. 2017 May 30;12(5):e0178032. doi: 10.1371/journal.pone.0178032. eCollection 2017
• Huppke P, Weissbach S, Church JA, Schnur R, Krusen M, Dreha-Kulaczewski S, Kühn-Velten WN, Wolf A, Huppke B, Millan F, Begtrup A, Almusafri F, Thiele H, Altmüller J, Nürnberg P, Müller M, Gärtner J (2017). Activating de novo mutations in NFE2L2 encoding NRF2 cause a multisystem disorder. Nat Commun. 2017 Oct 10;8(1):818. doi: 10.1038/s41467-017-00932-7
• Kanoungi G, Nürnberg P, Nothnagel M (2017). Securing the use of existing sample collections for future human genetic research. Eur J Hum Genet. 2017 May;25(5):522-529. doi: 10.1038/ejhg.2017.1. Epub 2017 Feb 1
• Khan AO, Becirovic E, Betz C, Neuhaus C, Altmüller J, Maria Riedmayr L, Motameny S, Nürnberg G, Nürnberg P, Bolz HJ (2017). A deep intronic CLRN1 (USH3A) founder mutation generates an aberrant exon and underlies severe Usher syndrome on the Arabian Peninsula. Sci Rep. 2017 May 3;7(1):1411. doi: 10.1038/s41598-017-01577-8
• Khan AO, Budde BS, Nürnberg P, Kawalia A, Lenzner S, Bolz HJ (2017). Genome-wide linkage and sequence analysis challenge CCDC66 as a human retinal dystrophy candidate gene and support a distinct NMNAT1-related fundus phenotype. Clin Genet. 2017 Mar 30. doi: 10.1111/cge.13022. [Epub ahead of print]
• Kudin AP, Baron G, Zsurka G, Hampel KG, Elger CE, Grote A, Weber Y, Lerche H, Thiele H, Nürnberg P, Schulz H, Ruppert AK, Sander T, Cheng Q, Arnér ES, Schomburg L, Seeher S, Fradejas-Villar N, Schweizer U, Kunz WS (2017). Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy. Free Radic Biol Med. 2017 May;106:270-277. doi: 10.1016/j.freeradbiomed.2017.02.040. Epub 2017 Feb 21
• Lang-Roth R, Fischer-Krall E, Kornblum C, Nürnberg G, Meschede D, Goebel I, Nürnberg P, Beutner D, Kubisch C, Walger M, Volk AE (2017). AUNA2: A Novel Type of Non-Syndromic Slowly Progressive Auditory Synaptopathy/Auditory Neuropathy with Autosomal-Dominant Inheritance. Audiol Neurootol. 2017;22(1):30-40. doi: 10.1159/000474929. Epub 2017 Jun 10
• Lessel D, Wu D, Trujillo C, Ramezani T, Lessel I, Alwasiyah MK, Saha B, Hisama FM, Rading K, Goebel I, Schütz P, Speit G, Högel J, Thiele H, Nürnberg G, Nürnberg P, Hammerschmidt M, Zhu Y, Tong DR, Katz C, Martin GM, Oshima J, Prives C, Kubisch C (2017). Dysfunction of the MDM2/p53 axis is linked to premature aging. J Clin Invest. 2017 Oct 2;127(10):3598-3608. doi: 10.1172/JCI92171. Epub 2017 Aug 28
• Li M, Maljevic S, Phillips AM, Petrovski S, Hildebrand MS, Burgess R, Mount T, Zara F, Striano P, Schubert J, Thiele H, Nürnberg P, Wong M, Weisenberg JL, Thio LL, Lerche H, Scheffer IE, Berkovic SF, Petrou S, Reid CA (2017). Gain-of-function HCN2 variants in genetic epilepsy. Hum Mutat. 2017 Oct 24. doi: 10.1002/humu.23357. [Epub ahead of print]
• Minnerop M, Kurzwelly D, Wagner H, Soehn AS, Reichbauer J, Tao F, Rattay TW, Peitz M, Rehbach K, Giorgetti A, Pyle A, Thiele H, Altmüller J, Timmann D, Karaca I, Lennarz M, Baets J, Hengel H, Synofzik M, Atasu B, Feely S, Kennerson M, Stendel C, Lindig T, Gonzalez MA, Stirnberg R, Sturm M, Roeske S, Jung J, Bauer P, Lohmann E, Herms S, Heilmann-Heimbach S, Nicholson G, Mahanjah M, Sharkia R, Carloni P, Brüstle O, Klopstock T, Mathews KD, Shy ME, de Jonghe P, Chinnery PF, Horvath R, Kohlhase J, Schmitt I, Wolf M, Greschus S, Amunts K, Maier W, Schöls L, Nürnberg P, Zuchner S, Klockgether T, Ramirez A, Schüle R (2017). Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia. Brain. 2017 Jun 1;140(6):1561-1578. doi: 10.1093/brain/awx095
• Moawia A, Shaheen R, Rasool S, Waseem SS, Ewida N, Budde B, Kawalia A, Motameny S, Khan K, Fatima A, Jameel M, Ullah F, Akram T, Ali Z, Abdullah U, Irshad S, Höhne W, Noegel AA, Al-Owain M, Hörtnagel K, Stöbe P, Baig SM, Nürnberg P, Alkuraya FS, Hahn A, Hussain MS (2017). Mutations of KIF14 cause primary microcephaly by impairing cytokinesis. Ann Neurol. 2017 Oct;82(4):562-577. doi: 10.1002/ana.25044. Epub 2017 Oct 14
• Moosa S, Altmüller J, Lyngbye T, Christensen R, Li Y, Nürnberg P, Yigit G, Vogel I, Wollnik B (2017). Novel compound heterozygous mutations in TELO2 in a patient with severe expression of You-Hoover-Fong syndrome. Mol Genet Genomic Med. 2017 Jul 28;5(5):580-584. doi: 10.1002/mgg3.287. eCollection 2017 Sep
• Moosa S, Haagerup A, Gregersen PA, Petersen KK, Altmüller J, Thiele H, Nürnberg P, Cho TJ, Kim OH, Nishimura G, Wollnik B, Vogel I (2017). Confirmation of CAGSSS syndrome as a distinct entity in a Danish patient with a novel homozygous mutation in IARS2. Am J Med Genet A. 2017 Apr;173(4):1102-1108. doi: 10.1002/ajmg.a.38116
• Moosa S, Loeys B, Altmüller J, Mortier G, Nürnberg P, Li Y, Wollnik B, Vogel I (2017). Metatarsal bony syndactyly in 2 fetuses with Smith-Lemli-Opitz syndrome: An under-recognized part of the clinical spectrum. Clin Genet. 2017 Sep;92(3):342-343. doi: 10.1111/cge.12990. Epub 2017 Mar 30
• Neidhardt G, Hauke J, Ramser J, Groß E, Gehrig A, Müller CR, Kahlert AK, Hackmann K, Honisch E, Niederacher D, Heilmann-Heimbach S, Franke A, Lieb W, Thiele H, Altmüller J, Nürnberg P, Klaschik K, Ernst C, Ditsch N, Jessen F, Ramirez A, Wappenschmidt B, Engel C, Rhiem K, Meindl A, Schmutzler RK, Hahnen E (2017). Association Between Loss-of-Function Mutations Within the FANCM Gene and Early-Onset Familial Breast Cancer. JAMA Oncol. 2017 Sep 1;3(9):1245-1248. doi: 10.1001/jamaoncol.2016.5592
• Ng M, Thakkar D, Southam L, Werker P, Ophoff R, Becker K, Nothnagel M, Franke A, Nürnberg P, Espirito-Santo AI, Izadi D, Hennies HC, Nanchahal J, Zeggini E, Furniss D (2017). A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis. Am J Hum Genet. 2017 Sep 7;101(3):417-427. doi: 10.1016/j.ajhg.2017.08.006
• Niturad CE, Lev D, Kalscheuer VM, Charzewska A, Schubert J, Lerman-Sagie T, Kroes HY, Oegema R, Traverso M, Specchio N, Lassota M, Chelly J, Bennett-Back O, Carmi N, Koffler-Brill T, Iacomino M, Trivisano M, Capovilla G, Striano P, Nawara M, Rzonca S, Fischer U, Bienek M, Jensen C, Hu H, Thiele H, Altmüller J, Krause R, May P, Becker F; EuroEPINOMICS Consortium, Balling R, Biskup S, Haas SA, Nürnberg P, van Gassen KLI, Lerche H, Zara F, Maljevic S, Leshinsky-Silver E (2017). Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features. Brain. 2017 Nov 1;140(11):2879-2894. doi: 10.1093/brain/awx236
• Pérez-Palma E, Helbig I, Klein KM, Anttila V, Horn H, Reinthaler EM, Gormley P, Ganna A, Byrnes A, Pernhorst K, Toliat MR, Saarentaus E, Howrigan DP, Hoffman P, Miquel JF, De Ferrari GV, Nürnberg P, Lerche H, Zimprich F, Neubauer BA, Becker AJ, Rosenow F, Perucca E, Zara F, Weber YG, Lal D (2017). Heterogeneous contribution of microdeletions in the development of common generalised and focal epilepsies. J Med Genet. 2017 Sep;54(9):598-606. doi: 10.1136/jmedgenet-2016-104495. Epub 2017 Jul 29
• Ralser DJ, Basmanav FB, Tafazzoli A, Wititsuwannakul J, Delker S, Danda S, Thiele H, Wolf S, Busch M, Pulimood SA, Altmüller J, Nürnberg P, Lacombe D, Hillen U, Wenzel J, Frank J, Odermatt B, Betz RC (2017). Mutations in γ-secretase subunit-encoding PSENEN underlie Dowling-Degos disease associated with acne inversa. J Clin Invest. 2017 Apr 3;127(4):1485-1490. doi: 10.1172/JCI90667. Epub 2017 Mar 13
• Reynolds JJ, Bicknell LS, Carroll P, Higgs MR, Shaheen R, Murray JE, Papadopoulos DK, Leitch A, Murina O, Tarnauskaitė Ž, Wessel SR, Zlatanou A, Vernet A, von Kriegsheim A, Mottram RM, Logan CV, Bye H, Li Y, Brean A, Maddirevula S, Challis RC, Skouloudaki K, Almoisheer A, Alsaif HS, Amar A, Prescott NJ, Bober MB, Duker A, Faqeih E, Seidahmed MZ, Al Tala S, Alswaid A, Ahmed S, Al-Aama JY, Altmüller J, Al Balwi M, Brady AF, Chessa L, Cox H, Fischetto R, Heller R, Henderson BD, Hobson E, Nürnberg P, Percin EF, Peron A, Spaccini L, Quigley AJ, Thakur S, Wise CA, Yoon G, Alnemer M, Tomancak P, Yigit G, Taylor AM, Reijns MA, Simpson MA, Cortez D, Alkuraya FS, Mathew CG, Jackson AP, Stewart GS (2017). Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism. Nat Genet. 2017 Apr;49(4):537-549. doi: 10.1038/ng.3790. Epub 2017 Feb 13
• Riessland M, Kaczmarek A, Schneider S, Swoboda KJ, Löhr H, Bradler C, Grysko V, Dimitriadi M, Hosseinibarkooie S, Torres-Benito L, Peters M, Upadhyay A, Biglari N, Kröber S, Hölker I, Garbes L, Gilissen C, Hoischen A, Nürnberg G, Nürnberg P, Walter M, Rigo F, Bennett CF, Kye MJ, Hart AC, Hammerschmidt M, Kloppenburg P, Wirth B (2017). Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. Am J Hum Genet. 2017 Feb 2;100(2):297-315. doi: 10.1016/j.ajhg.2017.01.005. Epub 2017 Jan 26
• Santolini I, Celli R, Cannella M, Imbriglio T, Guiducci M, Parisi P, Schubert J, Iacomino M, Zara F, Lerche H; EuroEPINOMICS CoGIE Consortium; Genetic Commission of Italian League Against Epilepsy (LICE), Moyanova S, Ngomba RT, van Luijtelaar G, Battaglia G, Bruno V, Striano P, Nicoletti F (2017). Alterations in the α₂ δ ligand, thrombospondin-1, in a rat model of spontaneous absence epilepsy and in patients with idiopathic/genetic generalized epilepsies. Epilepsia. 2017 Nov;58(11):1993-2001. doi: 10.1111/epi.13898. Epub 2017 Sep 15
• Scicluna BP, van Vught LA, Zwinderman AH, Wiewel MA, Davenport EE, Burnham KL, Nürnberg P, Schultz MJ, Horn J, Cremer OL, Bonten MJ, Hinds CJ, Wong HR, Knight JC, van der Poll T; MARS consortium (2017). Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study. Lancet Respir Med. 2017 Oct;5(10):816-826. doi: 10.1016/S2213-2600(17)30294-1. Epub 2017 Aug 29
• Scicluna BP, Wiewel MA, van Vught LA, Hoogendijk AJ, Klarenbeek AM, Franitza M, Toliat MR, Nürnberg P, Horn J, Bonten MJ, Schultz MJ, Cremer OL, van der Poll T (2017). A Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis Upon Intensive Care Unit Admission. Am J Respir Crit Care Med. 2017 Oct 3. doi: 10.1164/rccm.201707-1339LE. [Epub ahead of print]
• Usluer S, Kayserili MA, Eken AG, Yiş U, Leu C, Altmüller J, Thiele H, Nürnberg P, Sander T, Çağlayan SH (2017). Association of a synonymous SCN1B variant affecting splicing efficiency with Benign Familial Infantile Epilepsy (BFIE). Eur J Paediatr Neurol. 2017 Sep;21(5):773-782. doi: 10.1016/j.ejpn.2017.05.001. Epub 2017 May 13
• van Doormaal PTC, Ticozzi N, Weishaupt JH, Kenna K, Diekstra FP, Verde F, Andersen PM, Dekker AM, Tiloca C, Marroquin N, Overste DJ, Pensato V, Nürnberg P, Pulit SL, Schellevis RD, Calini D, Altmüller J, Francioli LC, Muller B, Castellotti B, Motameny S, Ratti A, Wolf J, Gellera C, Ludolph AC, van den Berg LH, Kubisch C, Landers JE, Veldink JH, Silani V, Volk AE (2017). The role of de novo mutations in the development of amyotrophic lateral sclerosis. Hum Mutat. 2017 Nov;38(11):1534-1541. doi: 10.1002/humu.23295. Epub 2017 Aug 3
• van Vught LA, Scicluna BP, Wiewel MA, Hoogendijk AJ, Klein Klouwenberg PMC, Ong DSY, Cremer OL, Horn J, Franitza M, Toliat MR, Nürnberg P, Bonten MMJ, Schultz MJ, van der Poll T; MARS Consortium (2017). Association of Gender With Outcome and Host Response in Critically Ill Sepsis Patients. Crit Care Med. 2017 Nov;45(11):1854-1862. doi: 10.1097/CCM.0000000000002649
• Weissbach S, Reinert MC, Altmüller J, Krätzner R, Thiele H, Rosenbaum T, Nürnberg P, Gärtner J (2017). A new CUL4B variant associated with a mild phenotype and an exceptional pattern of leukoencephalopathy. Am J Med Genet A. 2017 Oct;173(10):2803-2807. doi: 10.1002/ajmg.a.38390. Epub 2017 Aug 17
• Zaki M, Thoenes M, Kawalia A, Nürnberg P, Kaiser R, Heller R, Bolz HJ (2017). Recurrent and Prolonged Infections in a Child with a Homozygous IFIH1 Nonsense Mutation. Front Genet. 2017 Sep 22;8:130. doi: 10.3389/fgene.2017.00130. eCollection 2017

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Linda Partridge

• Augustin H, Adcott J, Elliott CJH, Partridge L (2017). Complex Roles of Myoglianin in Regulating Adult Performance and Lifespan. Fly (Austin), 1-6
•  Augustin H, McGourty K, Allen MJ, Madem SK, Adcott J, Kerr F, Wong CT, Vincent A, Godenschwege T, Boucrot E, Partridge L (2017). Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies. PLoS Biol. 15, e2001655
• Augustin H, McGourty K, Steinert JR, Cocheme HM, Adcott J, Cabecinha M, Vincent A, Halff EF, Kittler JT, Boucrot E, Partridge L (2017). Myostatin-like proteins regulate synaptic function and neuronal morphology. Development. In Press
• Bolukbasi E, Khericha M, Regan JC, Ivanov DK, Adcott J, Dyson MC, Nespital T, Thornton JM, Alic N, Partridge L (2017). Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity. Cell Rep. 2017 Oct 17;21(3):641-653. doi: 10.1016/j.celrep.2017.09.042
• Brandt T, Mourier A, Tain LS, Partridge L, Larsson NG, Kühlbrandt W (2017). Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. eLife. 6. 2017 Jul 12;6. pii: e24662. doi: 10.7554/eLife.24662. [Epub ahead of print]
• Bustos V, Partridge L (2017). Good Ol' Fat: Links between Lipid Signaling and Longevity. Trends. Biochem Sci. In press
• Gorsky MK, Burnouf S, Sofola-Adesakin O, Dols J, Augustin H, Weigelt CM, Grönke S, Partridge L (2017). Pseudo-acetylation of multiple sites on human Tau proteins alters Tau phosphorylation and microtubule binding, and ameliorates amyloid beta toxicity. Sci Rep. 7, 9984
• Hahn O, Grönke S, Stubbs TM, Ficz G, Hendrich O, Krueger F, Andrews S, Zhang Q, Wakelam MJ, Beyer A, Reik W, Partridge L (2017). Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. Genome Biol. 18(1):56
• Kennedy BK, Partridge L (2017). 2nd interventions in aging conference. Aging. 9, 1090-1095
• Kerr F, Sofola-Adesakin O, Ivanov DK, Gatliff J, Gomez Perez-Nievas B, Bertrand HC, Martinez P, Callard R, Snoeren I, Cocheme HM, Adcott J, Khericha M, Castillo-Quan JI, Wells G, Noble W, Thornton J, Partridge L (2017). Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease. PLoS Genet. 13, e1006593
• Mizielinska S, Ridler CE, Balendra R, Thoeng A, Woodling NS, Grässer FA, Plagnol V, Lashley T, Partridge L, Isaacs AM (2017). Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration. Acta Neuropathol Commun. 5, 29
• Moens TG, Partridge L, Isaacs AM (2017). Genetic models of C9orf72: what is toxic? Curr Opin Genet Dev. 44, 92-101
• Niccoli T, Partridge L, Isaacs AM (2017). Ageing as a risk factor for ALS/FTD. Hum Mol Genet. 2017 Oct 1;26(R2):R105-R113. doi: 10.1093/hmg/ddx247
• Piper MDW, Partridge L (2017). Drosophila as a model for ageing. Biochim Biophys Acta. 2017 Sep 28. pii: S0925-4439(17)30331-9. doi: 10.1016/j.bbadis.2017.09.016. [Epub ahead of print] Review
• Piper MDW, Soultoukis GA, Blanc E, Mesaros A, Herbert SL, Juricic P, He X, Atanassov I, Salmonowicz H, Yang M, Simpson SJ, Ribeiro C, Partridge L (2017). Matching dietary amino acid balance to the in silico-translated exome optimizes growth and reproduction without cost to lifespan. Cell Metab. 25, 610-621
• Simone R, Balendra R, Moens TG, Preza E, Wilson KM, Heslegrave A, Woodling NS, Niccoli T, Gilbert-Jaramillo J, Abdelkarim S, Clayton EL, Clarke M, Konrad MT, Nicoll AJ, Mitchell JS, Calvo A, Chio A, Houlden H, Polke JM, Ismail MA, Stephens CE, Vo T, Farahat AA, Wilson WD, Boykin DW, Zetterberg H, Partridge L, Wray S, Parkinson G, Neidle S, Patani R, Fratta P, Isaacs AM (2017). G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. EMBO Mol Med. 2017 Nov 7. pii: e201707850. doi: 10.15252/emmm.201707850. [Epub ahead of print]
• Tain LS, Sehlke R, Jain C, Chokkalingam M, Nagaraj N, Essers P, Rassner M, Grönke S, Fröhlich J, Dieterich C, Mann M, Alic N, Beyer A,  Partridge L (2017). A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance. Mol Syst Biol. 13, 939
• Zhao Y, Gilliat AF, Ziehm M, Turmaine M, Wang H, Ezcurra M, Yang C, Phillips G, McBay D, Zhang WB, Partridge L, Pincus Z, Gems D (2017). Two forms of death in ageing Caenorhabditis elegans. Nat Commun. 8, 15458
• Ziehm M, Kaur S, Ivanov DK, Ballester PJ, Marcus D, Partridge L, Thornton JM (2017). Drug repurposing for aging research using model organisms. Aging Cell. In Press. 2017 Jun 16. doi: 10.1111/acel.12626. [Epub ahead of print]

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Manolis Pasparakis

• Jaco I, Annibaldi A, Lalaoui N, Wilson R, Tenev T, Laurien L, Kim C, Jamal K, Wicky John S, Liccardi G, Chau D, Murphy JM, Brumatti G, Feltham R, Pasparakis M, Silke J, Meier P (2017). MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death. Mol Cell. 2017 Jun 1;66(5):698-710.e5. doi: 10.1016/j.molcel.2017.05.003. Epub 2017 May 11
• Kondylis V, Kumari S, Vlantis K, Pasparakis M (2017). The interplay of IKK, NF-κB and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation. Immunol Rev. 2017 May;277(1):113-127. doi: 10.1111/imr.12550. Review
• Lebrun A, Lo Re S, Chantry M, Izquierdo Carerra X, Uwambayinema F, Ricci D, Devosse R, Ibouraadaten S, Brombin L, Palmai-Pallag M, Yakoub Y, Pasparakis M, Lison D, Huaux F (2017). CCR2₊ monocytic myeloid-derived suppressor cells (M-MDSCs) inhibit collagen degradation and promote lung fibrosis by producing transforming growth factor-β1. J Pathol. 2017 Nov;243(3):320-330. doi: 10.1002/path.4956. Epub 2017 Sep 21
• Saleh D, Najjar M, Zelic M, Shah S, Nogusa S, Polykratis A, Paczosa MK, Gough PJ, Bertin J, Whalen M, Fitzgerald KA, Slavov N, Pasparakis M, Balachandran S, Kelliher M, Mecsas J, Degterev A (2017). Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide. J Immunol. 2017 Jun 1;198(11):4435-4447. doi: 10.4049/jimmunol.1601717. Epub 2017 May 1
• Van TM, Polykratis A, Straub BK, Kondylis V, Papadopoulou N, Pasparakis M (2017). Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017 Jun 30;127(7):2662-2677. doi: 10.1172/JCI92508. Epub 2017 Jun 19

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Mats Paulsson

• Franko A, Kunze A, Böse M, von Kleist-Retzow JC, Paulsson M, Hartmann U, Wiesner RJ (2017). Impaired Insulin Signaling is Associated with Hepatic Mitochondrial Dysfunction in IR_+/--IRS-1_+/-Double Heterozygous (IR-IRS1dh) Mice. Int J Mol Sci. 2017 May 30;18(6). pii: E1156. doi: 10.3390/ijms18061156
• Kárpáti S, Sárdy M, Németh K, Mayer B, Smyth N, Paulsson M, Traupe H (2017). Transglutaminases in autoimmune and inherited skin diseases: The phenomena of epitope spreading and functional compensation. Exp Dermatol. 2017 Sep 23. doi: 10.1111/exd.13449. [Epub ahead of print] Review
• Lau D, Elezagic D, Hermes G, Mörgelin M, Wohl AP, Koch M, Hartmann U, Höllriegl S, Wagener R, Paulsson M, Streichert T, Klatt AR (2017). The cartilage-specific lectin C-type lectin domain family 3 member A (CLEC3A) enhances tissue plasminogen activator-mediated plasminogen activation. J Biol Chem. 2017 Nov 16. pii: jbc.M117.818930. doi: 10.1074/jbc.M117.818930. [Epub ahead of print]

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Alvaro Rada-Iglesias

• Cruz-Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, van Ijcken WFJ, Grosveld F, Frommolt P, Bazzi H, Rada-Iglesias A (2017). Poised enhancers regulatory activity is topologically facilitated by polycomb. Cell Stem Cell. In press
• Ludwig KU, Böhmer AC, Bowes J, Nikolić M, Ishorst N, Wyatt N, Hammond NL, Gölz L, Thieme F, Barth S, Schuenke H, Klamt J, Spielmann M, Aldhorae K, Rojas-Martinez A, Nöthen MM, Rada-Iglesias A, Dixon MJ, Knapp M, Mangold E (2017). Imputation of Orofacial Clefting Data Identifies Novel Risk Loci and Sheds Light on the Genetic Background of Cleft Lip ± Cleft Palate and Cleft Palate Only. Hum Mol Genet. 2017 Jan 13. pii: ddx012. doi: 10.1093/hmg/ddx012. [Epub ahead of print]
• Rada-Iglesias A (2017). Ready, Set…Poised!: Polycomb target genes are bound by poised RNA polymerase II throughout differentiation. Mol Syst Biol. 2017 Oct 23;13(10):950. doi: 10.15252/msb.20177968
• Rehimi R, Bartusel M, Solinas F, Altmüller J, Rada-Iglesias A (2017). Chromatin Immunoprecipitation (ChIP) Protocol for Low-abundance Embryonic Samples. J Vis Exp. 2017 Aug 29;(126). doi: 10.3791/56186

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Hans Christian Reinhardt

• Brägelmann J, Dammert MA, Dietlein F, Heuckmann JM, Choidas A, Böhm S, Richters A, Basu D, Tischler V, Lorenz C, Habenberger P, Fang Z, Ortiz-Cuaran S, Leenders F, Eickhoff J, Koch U, Getlik M, Termathe M, Sallouh M, Greff Z, Varga Z, Balke-Want H, French CA, Peifer M, Reinhardt HC, Örfi L, Kéri G, Ansén S, Heukamp LC, Büttner R, Rauh D, Klebl BM, Thomas RK, Sos ML (2017). Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma. Cell Rep. 2017 Sep 19;20(12):2833-2845. doi: 10.1016/j.celrep.2017.08.082
• Doerr F, George J, Schmitt A, Beleggia F, Rehkämper T, Hermann S, Walter V, Weber JP, Thomas RK, Wittersheim M, Büttner R, Persigehl T, Reinhardt HC (2017). Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer. Sci Rep. 2017 Nov 14;7(1):15511. doi: 10.1038/s41598-017-15840-5
• Knittel G, Rehkämper T, Korovkina D, Liedgens P, Fritz C, Torgovnick A, Al-Baldawi Y, Al-Maarri M, Cun Y, Fedorchenko O, Riabinska A, Beleggia F, Nguyen PH, Wunderlich FT, Ortmann M, Montesinos-Rongen M, Tausch E, Stilgenbauer S, P Frenzel L, Herling M, Herling C, Bahlo J, Hallek M, Peifer M, Buettner R, Persigehl T, Reinhardt HC (2017). Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nat Commun. 2017 Jul 28;8(1):153. doi: 10.1038/s41467-017-00210-6
• Perkhofer L, Schmitt A, Romero Carrasco MC, Ihle M, Hampp S, Ruess DA, Hessmann E, Russell R, Lechel A, Azoitei N, Lin Q, Liebau S, Hohwieler M, Bohnenberger H, Lesina M, Algül H, Gieldon L, Schröck E, Gaedcke J, Wagner M, Wiesmüller L, Sipos B, Seufferlein T, Reinhardt HC, Frappart PO, Kleger A (2017). ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage. Cancer Res. 2017 Oct 15;77(20):5576-5590. doi: 10.1158/0008-5472.CAN-17-0634. Epub 2017 Aug 8
• Schiller J, Klein S, Engels M, Büttner R, Rybniker J, Fätkenheuer G, Scheid C, Wybranski C, Quaas A, Reinhardt HC, Waßermann R (2017). A Cryptosporidium infection in a patient with relapsed T lymphoblastic lymphoma undergoing allogeneic stem cell transplantation. Eur J Haematol. 2017 Nov 15. doi: 10.1111/ejh.12998. [Epub ahead of print]
• Schmitt A, Knittel G, Welcker D, Yang TP, George J, Nowak M, Leeser U, Büttner R, Perner S, Peifer M, Reinhardt HC (2017). ATM Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma. Cancer Res. 2017 Jun 1;77(11):3040-3056. doi: 10.1158/0008-5472.CAN-16-3398. Epub 2017 Mar 31

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Nirmal Robinson

• Ganesan R, Hos NJ, Gutierrez S, Fischer J, Stepek JM, Daglidu E, Krönke M, Robinson N (2017). Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLOS Pathog. doi:10.1371/journal.ppta.1006227, Epub: 13. Feb. 2017
• Gutiérrez S, Wolke M, Plum G, Robinson N (2017). Isolation of Salmonella typhimurium-containing Phagosomes from Macrophages. J Vis Exp. (128), e56514, doi:10.3791/56514 
• Hos NJ, Ganesan R, Gutiérrez S, Hos D, Klimek J,  Abdullah Z, Krönke M, Robinson N (2017). Type I interferon enhances necroptosis of Salmonella Typhimurium–infected macrophages by impairing antioxidative stress responses.  J Cell Biol. doi: 10.1083/jcb.201701107. Oct 20
• Robinson N (2017). Typhi colonization factor (Tcf) genetically conserved yet functionally diverse. Virulence 8(8): 1511-1512.

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Elena Rugarli

• Schatton D, Pla-Martin D, Marx MC, Hansen H, Mourier A, Nemazanyy I, Pessia A, Zentis P, Corona T, Kondylis V, Barth E, Schauss AC, Velagapudi V, Rugarli EI (2017). CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. doi: 10.1083/jcb.201607019
• Schatton D, Rugarli EI. (2017) Post-transcriptional regulation of mitochondrial function. Curr Op Physiol. epub doi.org/10.1016/j.cophys.2017.12.008    
• Aradjanski M, Dogan SA, Lotter S, Wang S, Hermans S, Wibom R, Rugarli E, Trifunovic A (2017). DARS2 protects against neuroinflammation and apoptotic neuronal loss, but is dispensable for myelin producing cells. Hum Mol Genet. 26, 4181-4189. doi: 10.1093/hmg/ddx307

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Bernhard Schermer

• Bartram MP, Mishra T, Reintjes N, Fabretti F, Gharbi H, Adam AC, Göbel H, Franke M, Schermer B, Haneder S, Benzing T, Beck BB, Müller RU (2017). Characterization of a splice-site mutation in the tumor suppressor gene FLCN associated with renal cancer. BMC Med Genet. 2017 May 12;18(1):53. doi: 10.1186/s12881-017-0416-5
• Ebner K, Dafinger C, Ortiz-Bruechle N, Koerber F, Schermer B, Benzing T, Dötsch J, Zerres K, Weber LT, Beck BB, Liebau MC (2017). Challenges in establishing genotype-phenotype correlations in ARPKD: case report on a toddler with two severe PKHD1 mutations. Pediatr Nephrol. 2017 Jul;32(7):1269-1273. doi: 10.1007/s00467-017-3648-x. Epub 2017 Mar 31
• Franke M, Baeßler B, Vechtel J, Dafinger C, Höhne M, Borgal L, Göbel H, Koerber F, Maintz D, Benzing T, Schermer B, Persigehl T (2017). Magnetic resonance T2 mapping and diffusion-weighted imaging for early detection of cystogenesis and response to therapy in a mouse model of polycystic kidney disease.Kidney Int. 2017 Jul 26. pii: S0085-2538(17)30394-0. doi: 10.1016/j.kint.2017.05.024. [Epub ahead of print]
• Koehler S, Brähler S, Braun F, Hagmann H, Rinschen MM, Späth MR, Höhne M, Wunderlich FT, Schermer B, Benzing T, Brinkkoetter PT(2017). Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes. Kidney Int. 2017 Jun;91(6):1510-1517. doi: 10.1016/j.kint.2016.12.011. Epub 2017 Feb 7
• Kohli P, Höhne M, Jüngst C, Bertsch S, Ebert LK, Schauss AC, Benzing T, Rinschen MM, Schermer B. The ciliary membrane-associated proteome reveals actin-binding proteins as key components of cilia. EMBO Rep. 2017 Sep;18(9):1521-1535. doi: 10.15252/embr.201643846. Epub 2017 Jul 14
• Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B (2017). YAP-mediated mechanotransduction determines the podocyte's response to damage. Sci Signal. 2017 Apr 11;10(474). pii: eaaf8165. doi: 10.1126/scisignal.aaf8165
• Rinschen MM, Hoppe AK, Grahammer F, Kann M, Völker LA, Schurek EM, Binz J, Höhne M, Demir F, Malisic M, Huber TB, Kurschat C, Kizhakkedathu JN, Schermer B, Huesgen PF, Benzing T(2017). N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton. J Am Soc Nephrol. 2017 Oct;28(10):2867-2878. doi: 10.1681/ASN.2016101119. Epub 2017 Jul 19

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Björn Schumacher

• Bujarrabal A, Schumacher B (2017). Tracking senescent cells: A new biomarker assay opens new avenues in senescence research. Mech Ageing Dev. 2017 Feb 1. pii: S0047-6374(16)30293-7. doi: 10.1016/j.mad.2017.01.009
• Edifizi D, Nolte H, Babu V, Castells-Roca L, Mueller MM, Brodesser S, Krüger N, Schumacher B (2017). Multilayered reprogramming in response to persistent DNA damage in C. elegans. Cell Reports. 2017 Aug 29;20(9):2026-2043
• Edifizi D, Schumacher B (2017). Omics Approaches for Identifyiung Physiological Adaptations to Genome Instability in Aging. Int J Mol Sci. 2017, 18(11), 2329; doi: 10.3390/ijms18112329
• Garinis GA, Schwer B, Schumacher B (2017). Editorial: DNA damage & immunity. Mech Ageing Dev. 2017 Apr 23. pii: S0047-6374(17)30097-0. doi: 10.1016/j.mad.2017.04.006. [Epub ahead of print]
• Lohmann G, Schumacher B, Herling M (2017). Nucleotide excision repair as a targetable vulnerability in leukemia. Oncotarget. 2017 Dec 6;8(70):114420-114421. doi: 10.18632/oncotarget.22998. eCollection 2017 Dec 29.
• Ou HL, Schumacher B (2017). DNA damage responses and p53 in the aging process. Blood. 2017 :blood-2017-07-746396; doi: 10.1182/blood-2017-07-746396
• Rieckher M, Bujarrabal A, Doll MA, Soltanmohammadi N, Schumacher B (2017). A simple answer to complex questions: C. elegans as an experimental model for examining the DNA damageresponse and disease genes. J Cell Physiol. 2017 May 2. doi: 10.1002/jcp.25979. [Epub ahead of print]
• Wilson DM3rd, Rieckher M, Williams AB, Schumacher B (2017). Systematic analysis of DNA crosslink repair pathways during development and aging in C. elegans. Nucleic Acids Res. 2017. doi:10.1093/nar/gkx660 

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Günter Schwarz

• Kalimuthu P, Belaidi AA, Schwarz G, Bernhardt PV (2017). Chitosan-Promoted Direct Electrochemistry of Human Sulfite Oxidase. J Phys Chem B. 2017 Oct 5;121(39):9149-9159. doi: 10.1021/acs.jpcb.7b06712. Epub 2017 Sep 21
• Kumar A, Dejanovic B, Hetsch F, Semtner M, Fusca D, Arjune S, Santamaria-Araujo JA, Winkelmann A, Ayton S, Bush AI, Kloppenburg P, Meier JC, Schwarz G, Belaidi AA (2017). S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency. J Clin Invest. 2017 Nov 6. pii: 89885. doi: 10.1172/JCI89885. [Epub ahead of print]

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Sophie Steculorum

• Ruud J, Steculorum SM, Brüning JC. (2017) Neuronal control of peripheral insulin sensitivity and glucose metabolism. Nature Communications, 4;8:15259
• Steculorum SM, Timper K, Engström Ruud L, Evers N, Paeger L, Bremser S, Kloppenburg P  & Brüning JC. Inhibition of P2Y6-signaling in AgRP-neurons reduces food intake and improves systemic insulin sensitivity in obesity. Cell Reports, 18(7):1587-1597.
• Timper K, Denson JL, Steculorum SM, Hellinger C, Engström Ruud L, Wunderlich CM,  Rose-John S, Wunderlich FT & Brüning JC. IL-6 improves energy and glucose  homeostasis in obesity via enhanced central IL-6 trans-signaling. Cell Reports,
  11;19(2):267-28.

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Philipp Steven

• Gehlsen U, Braun T, Notara M, Krösser S, Steven P (2017). A semifluorinated alkane (F4H5) as novel carrier for cyclosporine A: a promising therapeutic and prophylactic option for topical treatment of dry eye. Graefes Arch Clin Exp Ophthalmol. 2017 Jan 14. doi: 10.1007/s00417-016-3572-y. Epub 2017 Jan 14
• Horstmann J, Schulz-Hildebrandt H, Bock F, Siebelmann S, Lankenau E, Hüttmann G, Steven P, Cursiefen C (2017). Label-Free In Vivo Imaging of Corneal Lymphatic Vessels Using Microscopic Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2017 Nov 1;58(13):5880-5886. doi: 10.1167/iovs.17-22286
• Hos D, Bukowiecki A, Horstmann J, Bock F, Bucher F, Heindl LM, Siebelmann S, Steven P, Dana R, Eming SA, Cursiefen C (2017). Transient Ingrowth of Lymphatic Vessels into the Physiologically Avascular Cornea Regulates Corneal Edema and Transparency. Sci Rep. 2017 Aug 3;7(1):7227. doi: 10.1038/s41598-017-07806-4
• Osae AE, Gehlsen U, Horstmann J, Siebelmann S, Stern ME, Kumah DB, Steven P (2017). Epidemiology of dry eye disease in Africa: The sparse information, gaps and opportunities. Ocul Surf. 2017 Jan 5. pii: S1542-0124(16)30069-6. doi: 10.1016/j.jtos.2017.01.001. [Epub ahead of print].  Review
• Steven P, Augustin AJ, Geerling G, Kaercher T, Kretz F, Kunert K, Menzel-Severing J, Schrage N, Schrems W, Krösser S, Beckert M, Messmer EM (2017). Semifluorinated Alkane Eye Drops for Treatment of Dry Eye Disease Due to Meibomian Gland Disease. J Ocul Pharmacol Ther. 2017 Nov;33(9):678-685. doi: 10.1089/jop.2017.0042. Epub 2017 Sep 18
• Steven P, Siebelmann S, Hos D, Cursiefen C (2017). Immune Reactions and Dry Eye after Posterior Lamellar Keratoplasty. Current Treatment Options for Fuchs Endothelial Dystrophy. pp 227-235, Springer 

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Wilhelm Stoffel

• Stoffel W, Schmidt-Soltau I, Jenke B, Binczek E, Hammels I (2017). Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by tA Artificial Lipid Barrier. J Invest Dermatol. doi:10.1016/j.jid.2017.02.97

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Aleksandra Trifunovic

• Aradjanski M, Dogan SA, Lotter S, Wang S, Hermans S, Wibom R, Rugarli EI, Trifunovic A (2017). DARS2 protects against neuroinflammation and apoptotic neuronal loss, but is dispensable for myelin producing cells. Hum Mol Genet. In press
• Szczepanowska K, Trifunovic A (2017). Origins of mtDNA mutations in ageing. Essays Biochem. 2017 Jul 11;61(3):325-337. doi: 10.1042/EBC20160090. Print 2017 Jul 15. Review
• Theisen BE, Rumyantseva A, Cohen JS, Alcaraz WA, Shinde DN, Tang S, Srivastava S, Pevsner J, Trifunovic A, Fatemi A (2017). Deficiency of WARS2, encoding mitochondrial tryptophanyl tRNA synthetase, causes severe infantile onset leukoencephalopathy. Am J Med Genet A. 2017 Sep;173(9):2505-2510. doi: 10.1002/ajmg.a.38339. Epub 2017 Jun 26

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Dario Valenzano

• Smith P, Willemsen D, Popkes M, Metge F, Gandiwa E, Reichard M, Valenzano DR (2017). Regulation of Life Span by the Gut Microbiota in The Short-Lived African Turquoise Killifish. Elife. Aug 22;6. doi: 10.775/eLife.27014
• Valenzano DR, Aboobaker A, Seluanov A, Gorbunova V (2017). Non-canonical aging model systems and why we need them. EMBO J. DOI: 10.15252/embj.201796837

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David Vilchez

• Koyuncu S, Fatima A, Gutierrez-Garcia R, Vilchez D (2017). Proteostasis of Huntingtin in Health and Disease. Int J Mol Sci. 2017 Jul 19;18(7). pii: E1568. doi: 10.3390/ijms18071568. Review. PMID: 28753941
• Lee HJ, Bartsch D, Xiao C, Guerrero S, Ahuja G, Schindler C, Moresco JM, Yates III JR, Gebauer F, Bazzi H, Dieterich C, Kurian L, Vilchez D (2017). A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells. Nat Commun. 8: 1456
• Noormohammadi A, Calculli G, Gutierrez-Garcia R, Khodakarami A, Koyuncu S, Vilchez D (2017). Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells. Cell Mol Life Sci. 2017 Jul 26. doi: 10.1007/s00018-017-2602-1. [Epub ahead of print] Review. PMID: 28748323

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Silvia von Karstedt

• Hartwig, T.*, Montinaro, A.*, von Karstedt, S.*, Sevko, A., Surinova, S., Chakravarthy, A., Taraborrelli, L., Draber, P., Lafont, E., Arce Vargas, F., Bahrawy, M. A., Quezada, S. A. and Walczak, H; The TRAIL-induced cancer secretome promotes a tumor-supportive immune-microenvironment via CCR2. Molecular Cell65, 730–742.e5 (2017). * equal contribution
• von Karstedt, S.*, Montinaro, A. * and Walczak, H; Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy. Nature Reviews Cancer17, 352–366 (2017).

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Sara Wickström

• Elzeneini E, Wickström SA (2017). Lipodystrophic laminopathy: Lamin A mutation relaxes chromatin architecture to impair adipogenesis. J Cell Biol. 2017 Sep 4;216(9):2607-2610. doi: 10.1083/jcb.201707090. Epub 2017 Aug 15
• Miroshnikova YA, Le HQ, Schneider D, Thalheim T, Rübsam M, Bremicker N, Polleux J, Kamprad N, Tarantola M, Wang I, Balland M, Niessen CM, Galle J, Wickström SA (2017). Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification. Nat Cell Biol. 2017 Dec 11. doi: 10.1038/s41556-017-0005-z. [Epub ahead of print]
• Miroshnikova YA, Nava MM, Wickström SA (2017). Emerging roles of mechanical forces in chromatin regulation. J Cell Sci. 2017 Jul 15;130(14):2243-2250. doi: 10.1242/jcs.202192. Epub 2017 Jun 23. Review
• Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B (2017). YAP-mediated mechanotransduction determines the podocyte's response to damage. Sci Signal. 2017 Apr 11;10(474). pii: eaaf8165. doi: 10.1126/scisignal.aaf8165
• Rübsam M, Broussard JA, Wickström SA, Nekrasova O, Green KJ, Niessen CM (2017). Adherens Junctions and Desmosomes Coordinate Mechanics and Signaling to Orchestrate Tissue Morphogenesis and Function: An Evolutionary Perspective. Cold Spring Harb Perspect Biol. 2017 Sep 11. pii: a029207. doi: 10.1101/cshperspect.a029207. [Epub ahead of print]
• Rübsam M, Mertz AF, Kubo A, Marg S, Jüngst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M, Wickström SA, Niessen CM (2017). E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning. Nat Commun. 2017 Nov 1;8(1):1250. doi: 10.1038/s41467-017-01170-7

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Rudolf J. Wiesner

• Franko A, Kunze A, Böse M, von Kleist-Retzow JC, Paulsson M, Hartmann U, Wiesner RJ (2017). Impaired insulin signaling is associated with hepatic mitochondrial dysfunction in IR^+/--IRS-1^+/- double heterozygous (IR-IRS1dh) mice. Int J Mol Sci.
• Neuhaus JFG, Baris OR, Kittelmann A, Becker K, Rothschild MA, Wiesner RJ (2017). Catecholamine metabolism induces mitochondrial DNA deletions in the adrenal medulla and leads to severe adrenal degeneration during aging. Neuroendocrinology. 104: 72-84
• Schommers P, Thurau A, Bultmann-Mellin I, Guschlbauer M, Klatt AR, Rozman J, Klingenspor M, Hrabe de Angelis M, Alber J, Gründemann D, Sterner-Kock A, Wiesner RJ (2017). Metformin causes a futile intestinal-hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state. Mol Metab.
• Stöckigt F, Beiert T, Knappe V, Baris OR, Wiesner RJ, Clemen CS, Nickenig G, Andrié RP, Schrickel JW (2017). Aging-related mitochondrial dysfunction facilitates the occurrence of serious arrhythmia after myocardial infarction. Biochem Biophys Res Comm 493: 604- 610.
• Weiland D, Brachvogel B, Hornig-Do HT, Neuhaus JFG, Holzer T, Tobin DJ, Niessen CM, Wiesner RJ, Baris OR (2017). Imbalance of mitochondrial respiratory chain complexes in the epidermis induces severe skin inflammation. J Invest Dermatol.

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Andreas Wodarz

• Berger H, Wodarz A, Borchers A (2017). PTK7 Faces the Wnt in Development and Disease. Front Cell Dev Biol. 05 April 2017. DOI 10.3389/fcell.2017.00031    
• Januschke J, Wodarz A (2017). Notch Signaling: Where Is the Action? Curr Biol. 27, R760-R762

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Thomas Wunderlich

• Bergmann J, Müller M, Baumann N, Reichert M, Heneweer C, Bolik J, Lücke K, Gruber S, Carambia A, Boretius S, Leuschner I, Becker T, Rabe B, Herkel J, Wunderlich FT, Mitrücker HW, Rose-John S, Schmidt-Arras D (2017). IL-6 trans-signaling is essential for the development of hepatocellular carcinoma. Hepatology. 2017 Jan; 65(1):89-103
• Drees C, Vahl JC, Bortoluzzi S, Heger KD, Fischer JC, Wunderlich FT, Peschel C, Schmidt-Supprian M (2017). Roquin Paralogs Differentially Regulate Functional NKT Cell Subsets. J Immunol. 2017 Feb 10. pii: 1601732
• Heink S, Yogev N, Garbers C, Herwerth M, Aly L, Gasperi C, Husterer V, Croxford AL, Möller-Hackbarth K, Bartsch HS, Sotlar K, Krebs S, Regen T, Blum H, Hemmer B, Misgeld T, Wunderlich FT, Hidalgo J, Oukka M, Rose-John S, Schmidt-Supprian M, Waisman A, Korn T (2017). Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells. Nat Immunol. 2017 Jan;18(1):74-85
• Koehler S, Brähler S, Braun F, Hagmann H, Rinschen MM, Späth MR, Höhne M, Wunderlich FT, Schermer B, Benzing T, Brinkkoetter PT (2017). Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes. Kidney Int. 2017 Feb 7. pii: S0085-2538(16)30745-1
• Loeffelholz von C, Lieske S, Neuschäfer-Rube F, Willmes DM, Raschzok N, Sauer IM, König J, Fromm M, Horn P, Chatzigeorgiou A, Pathe-Neuschäfer-Rube A, Jordan J, Pfeiffer AF, Mingrone G, Bornstein SR, Stroehle P, Harms C, Wunderlich FT, Helfand SL, Bernier M, de Cabo R, Shulman GI, Chavakis T, Püschel GP, Birkenfeld AL (2017). The Human Longevity Gene Homolog INDY and Interleukin-6 Interact in Hepatic Lipid Metabolism. Hepatology. 2017 Jan 30             
• Awazawa M, Gabel P, Tsaousidou E, Nolte H, Kruger M, Schmitz J, Ackermann PJ, Brandt C, Altmuller J, Motameny S, Wunderlich FT, Kornfeld JW, Blüher M, Brüning JC (2017). A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. Nat Med. 2017, 23, 1466-1473, doi:10.1038/nm.4420
• Peche VS, Holak TA, Burgute BD, Kosmas K, Kale SP, Wunderlich FT, Elhamine F, Stehle R, Pfitzer G, Nohroudi K, Addicks K, Stöckigt F, Schrickel JW, Gallinger J, Schleicher M, Noegel AA (2017). Erratum to: Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy. Cell Mol Life Sci. 2017, 74, 4045, doi:10.1007/s00018-017-2630-x
• Knittel G, Rehkamper T, Korovkina D, Liedgens P, Fritz C, Torgovnick A, Al-Baldawi Y, Al-Maarri M, Cun Y, Fedorchenko O, Riabinska A, Beleggia F, Nguyen PH, Wunderlich FT, Ortmann M, Montesinos-Rongen M, Tausch E, Stilgenbauer SP, Frenzel L, Herling M, Herling C, Bahlo J, Hallek M, Peifer M, Buettner R, Persigehl T, Reinhardt HC (2017). Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nat Commun. 2017, 8, 153, doi:10.1038/s41467-017-00210-6
• Theurich S, Tsaousidou E, Hanssen R, Lempradl AM, Mauer J, Timper K, Schilbach K, Folz-Donahue K, Heilinger C, Sexl V, Pospisilik JA, Wunderlich FT, Brüning JC (2017). IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis. Cell Metab. 2017, 26, 171-184 e176, doi:10.1016/j.cmet.2017.05.018
• Xu E, Pereira MMA, Karakasilioti I, Theurich S, Al-Maarri M, Rappl G, Waisman A, Wunderlich FT, Bruning JC (2017). Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance. Nat Commun. 2017 May 3;8:14803. doi: 10.1038/ncomms14803
• Reissig S, Tang Y, Nikolaev A, Gerlach K, Wolf C, Davari K, Gallus C, Masri J, Mufazalov IA, Neurath MF, Wunderlich FT, Schattenberg JM, Galle PR, Weigmann B, Waisman A, Glasmacher E, Hövelmeyer N (2017). Elevated levels of Bcl-3 inhibits Treg development and function resulting in spontaneous colitis. Nat Commun. 2017 Apr 28;8:15069. doi: 10.1038/ncomms15069
• Timper K, Denson JL, Steculorum SM, Heilinger C, Engstrom-Ruud L, Wunderlich CM, Rose-John S, Wunderlich FT, Bruning JC (2017). IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling. Cell Rep. 2017 Apr 11;19(2):267-280. doi: 10.1016/j.celrep.2017.03.043
• Lauterbach MA, Wunderlich FT (2017). Macrophage function in obesity-induced inflammation and insulin resistance. Pflugers Arch. 2017 Apr;469(3-4):385-396. doi: 10.1007/s00424-017-1955-5. Epub 2017 Feb 23

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