AB C​​​​​​​ D E F G​​​​​​​ H I J​​​​​​​ K​​​​​​​ L​​​​​​​ M N O P​​​​​​​ Q​​​​​​​ R​​​​​​​ S​​​​​​​ T​​​​​​​ U​​​​​​​ V​​​​​​​ W​​​​​​​ X​​​​​​​ Y​​​​​​​ Z​​​​​​​​​​​​​​​​​​​​​

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Adam Antebi

• Huang, W.M., Kew, C., Fernandes, S.D., Lohrke, A., Han, L., Demetriades, C., and Antebi, A. (2022). Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity. Nature Aging2, 796-+. 10.1038/s43587-022-00275-z.
• Huang, W., Kew, C., Fernandes, S.A., Lohrke, A., Han, L., Demetriades, C., and Antebi, A. (2022). Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity. Nat Aging2, 796-808. 10.1038/s43587-022-00275-z.
• Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T,Schermer B, Schwarz G, Burst V, Müller RU (2022). A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism. Transl Res. 2022 Feb 18:S1931-5244(22)00023-8. doi: 10.1016/j.trsl.2022.02.003. Epub ahead of print. PMID: 35189406.
• Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J.A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S.Q., Chen, B.H., Ermolaeva, M., Ewald, C.Y., Ferrucci, L., Florian, M.C., Fortney, K., Freund, A., Georgievskaya, A., Gladyshev, V.N., Glass, D., Golato, T., Gorbunova, V., Hoejimakers, J., Houtkooper, R.H., Jager, S., Jaksch, F., Janssens, G., Jensen, M.B., Kaeberlein, M., Karsenty, G., de Keizer, P., Kennedy, B., Kirkland, J.L., Kjaer, M., Kroemer, G., Lee, K.F., Lemaitre, J.M., Liaskos, D., Longo, V.D., Lu, Y.X., MacArthur, M.R., Maier, A.B., Manakanatas, C., Mitchell, S.J., Moskalev, A., Niedernhofer, L., Ozerov, I., Partridge, L., Passegué, E., Petr, M.A., Peyer, J., Radenkovic, D., Rando, T.A., Rattan, S., Riedel, C.G., Rudolph, L., Ai, R.X., Serrano, M., Schumacher, B., Sinclair, D.A., Smith, R., Suh, Y., Taub, P., Trapp, A., Trendelenburg, A.U., Valenzano, D.R., Verburgh, K., Verdin, E., Vijg, J., Westendorp, R.G.J., Zonari, A., Bakula, D., Zhavoronkov, A., and Scheibye-Knudsen, M. (2022). Meeting Report: Aging Research and Drug Discovery. Aging-Us14, 530-543.
• Ravanelli S, Li Q, Annibal A, Trifunovic A, Antebi A, Hoppe T (2022). Reprograming of proteasomal degradation by branched chain amino acid metabolism. Aging Cell. 2022 Sep 27:e13725. doi: 10.1111/acel.13725. Epub ahead of print. PMID: 36168305.
• Steiner, J., Antebi, A., Annibal, A., and Kubacki, T. (2022). A Novel Tnfrsf1a Mutation Associated with Tnf-Receptor Associated Periodic Syndrome and Its Metabolic Signature. Ann Rheum Dis81, 348-349. 10.1136/annrheumdis-2022-eular.1098.
• Wang X, Jiang Q, Song Y, He Z, Zhang H, Song M, Zhang X, Dai Y, Karalay O, Dieterich C, Antebi A, Wu L, Han JJ, Shen Y (2022). Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans. EMBO J. 2022 Apr 19;41(8):e109633. doi: 10.15252/embj.2021109633. Epub 2022 Mar 7. PMID: 35253240.

Miguel A. Alejandre Alcazar

• Obst S, Herz J, Alejandre Alcazar MA, Endesfelder S, Möbius MA, Rüdiger M, Felderhoff-Müser U, Bendix I (2022). Perinatal Hyperoxia and Developmental Consequences on the Lung-Brain Axis. Oxid Med Cell Longev. 2022 Feb 24;2022:5784146. doi: 10.1155/2022/5784146. PMID: 35251477; PMCID: PMC8894035.
• Trojan T, Alejandre Alcazar MA, Fink G, Thomassen JC, Maessenhausen MV, Rietschel E, Schneider PM, van Koningsbruggen-Rietschel S (2022). The effect of TGF-β₁ polymorphisms on pulmonary disease progression in patients with cystic fibrosis.BMC Pulm Med. 2022 May 7;22(1):183. doi: 10.1186/s12890-022-01977-1. PMID: 35525938; PMCID: PMC9080196.
• Kasper P, Selle J, Vohlen C, Wilke R, Kuiper-Makris C, Klymenko O, Bae-Gartz I, Schömig C, Quaas A,Schumacher B, Demir M, Bürger M, Lang S, Martin A, Steffen HM, Goeser T, Dötsch J, Alcazar MAA (2022). Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice. Int J Mol Sci. 2022 May 17;23(10):5609. doi: 10.3390/ijms23105609. PMID: 35628414; PMCID: PMC9144113.
• Selle, J., Abend, B., Klymenko, O., Georgomanolis, T., Vohlen, C., Wilke, R., Dötsch, J., and Alcazar, M.A.A. (2022). Perinatal Overactive Adipose Tissue Induces DNA Damage Response, Loss of Alveolar Epithelial Cells Type II (ATII) and Arrest Alveolarization. Am J Resp Crit Care205.
• Selle J, Dinger K, Jentgen V, Zanetti D, Will J, Georgomanolis T, Vohlen C, Wilke R, Kojonazarov B, Klymenko O, Mohr J, V Koningsbruggen-Rietschel S, Rhodes CJ, Ulrich A, Hirani D, Nestler T, Odenthal M, Mahabir E, Nayakanti S, Dabral S, Wunderlich T, Priest J, Seeger W, Dötsch J, Pullamsetti SS, Alejandre Alcazar MA (2022). Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. Nat Commun. Jul 27;13(1):4352. doi: 10.1038/s41467-022-31655-z. PMID: 35896539; PMCID: PMC9329333.
• Voggel J, Fink G, Zelck M, Wohlfarth M, Post JM, Bindila L, Rauh M, Amann K, Alejandre Alcázar MA, Dötsch J, Nüsken KD, Nüsken E (2022). Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats. J Lipid Res. 2022 Sep 21;63(11):100283. doi: 10.1016/j.jlr.2022.100283. Epub ahead of print. PMID: 36152882; PMCID: PMC9619183.
• Voggel, J., Mohr, J., Nüsken, K.D., Dötsch, J., Nüsken, E., and Alcazar, M.A.A. (2022). Translational insights into mechanisms and preventive strategies after renal injury in neonates. Semin Fetal Neonat M27. ARTN 101245. 10.1016/j.siny.2021.101245.
• Bartz, C., Hirani, D., Selle, J., Vohlen, C., Wilke, R., Kuiper-Makris, C., Nies, C., Wagde, V., Dötsch, J., and Alcazar, M.A.A. (2022). Targeting IL-6 to prevent vascular and bronchial remodeling in an experimental model of bronchopulmonary dysplasia. Klin Padiatr234, 317-318. 10.1055/s-0042-1754452.
• Bartz, C.M., Hirani, D.V., Selle, J., Vohlen, C., Wilke, R., Kuiper-Makris, C., Nies, C., Wagde, V., Doetsch, J., and Alcazar, M.A.A. (2022). Targeting IL-6 to Prevent Vascular and Bronchial Remodeling in an Experimental Model of BPD. Am J Resp Crit Care205.
• Hirani, D.A., Thielen, F., Vohlen, C., Danopoulos, S., Mansouri, S., Haznedar-Karakaya, P., Mohr, J., Wilke, R., Koningsbruggen-Rietschel, S., Al-Alam, D., Savai, R., Dösch, J., and Alcazar, M.A.A. (2022). CXCL10 deficiency protects from lung macrophage invasion and enables lung growth during acute injury and recovery in experimental bronchopulmonary dysplasia. Klin Padiatr234, 342-343. 10.1055/s-0042-1754519.
• Hirani, D., Alvira, C.M., Danopoulos, S., Milla, C., Donato, M., Tian, L., Mohr, J., Dinger, K., Vohlen, C., Selle, J., Koningsbruggen-Rietschel, S.V., Barbarino, V., Pallasch, C., Rose-John, S., Odenthal, M., Pryhuber, G.S., Mansouri, S., Savai, R., Seeger, W., Khatri, P., Al Alam, D., Dötsch, J., and Alcazar, M.A.A. (2022). Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia. Eur Respir J59. Artn 2002248. 10.1183/13993003.02248-2020.

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Hisham Bazzi

• Khatif, H., Wirtz, L., Soroka, E., and Bazzi, H. (2022). The Striatin-Interacting Phosphatase And Kinases complex is important for skin epidermal differentiation and barrier formation. J Invest Dermatol142, S210-S210.
• Khatif, H., and Bazzi, H. (2022). The Wnt-inhibitor Dkk4 is required for primary hair follicle induction and patterning. J Invest Dermatol142, S125-S125.
• Wirtz, I., Damen, M., Khatif, H., Soroka, E., Simons, B., and Bazzi, H. (2022). Yap and Notch signaling activities correlate with the two phases of skin epidermal stratification during development. J Invest Dermatol142, S210-S210.

Matteo Bergami

• Wani GA, Sprenger HG, Ndoci K, Chandragiri S, Acton RJ, Schatton D, Kochan SMV, Sakthivelu V, Jevtic M, Seeger JM, Müller S, Giavalisco P, Rugarli EI, Motori E, Langer T,Bergami M (2022). Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.Cell Rep. 2022 Feb 15;38(7):110370. doi: 10.1016/j.celrep.2022.110370. PMID: 35172139.

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Thomas Benzing

• Hof, A, Geißen, S, Singgih, K, Mollenhauer, M, Winkels, H, Benzing, T, Baldus, S, Hoyer, FF (2022). Myeloid leukocytes’ diverse effects on cardiovascular and systemic inflammation in chronic kidney disease. Basic Res Cardiol 117, 38. doi.org/10.1007/s00395-022-00945-4
• Rogg, M, Maier, JI, Van Wymersch, C, Helmstädter, M, Sammarco, A, Lindenmeyer, M, Zareba, P, Montanez, E, Walz, G, Werner, M, Endlich, N, Benzing, T, Huber, TB, Schell, C (2022). α-Parvin Defines a Specific Integrin Adhesome to Maintain the Glomerular Filtration Barrier. J Am Soc Nephrol 33, 786–808. doi.org/10.1681/ASN.2021101319
• Unnersjö-Jess, D, Ramdedovic, A, Höhne, M, Butt, L, Koehler, FC, Müller, R-., Hoyer, PF, Blom, H, Schermer, B, Benzing, T(2022). Three-Dimensional Super-Resolved Imaging of Paraffin-Embedded Kidney Samples. Kidney360 3, 446–454. doi.org/10.34067/KID.0005882021
• Kühne, L, Völker, LA, Hagmann, H, Hägele, H, Osterholt, T, Eichenauer, DA, Thomas, A, Breuer, J, Grüttner, B, Gottschalk, I, Kann, M, Benzing, T, Thevis, M, Müller, AM, Brinkkoetter, PT (2022). First use of the anti-VWF nanobody caplacizumab to treat iTTP in pregnancy. Br J Haematol 196, e30–e33. doi.org/10.1111/bjh.17833
• Lagolio, E, Demurtas, J, Buzzetti, R, Cortassa, G, Bottone, S, Spadafora, L, Cocino, C, Smith, L, Benzing, T, Polidori, MC (2022). A rapid and feasible tool for clinical decision making in community-dwelling patients with COVID-19 and those admitted to emergency departments: the Braden-LDH-HorowITZ Assessment-BLITZ. Intern Emerg Med 17, 839–844. doi.org/10.1007/s11739-021-02805-w
• Koehler, S., Odenthal, J., Ludwig, V., Unnersjö Jess, D., Höhne, M., Jüngst, C., Grawe, F., Helmstädter, M., Janku, J.L., Bergmann, C., Hoyer, P.F., Hagmann, H.H., Walz, G., Bloch, W., Niessen, C., Schermer, B., Wodarz, A., Denholm, B., Benzing, T., Iden, S., Brinkkoetter, P.T. (2022). Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int 101, 733–751. doi.org/10.1016/j.kint.2021.11.030
• Butt L, Unnersjö-Jess D, Höhne M, Hahnfeldt R, Reilly D, Rinschen MM, Plagmann I, Diefenhardt P, Brähler S, Brinkkötter PT, Brismar H, Blom H, Schermer B, Benzing T (2022). Super-Resolution Imaging of the Filtration Barrier Suggests a Role for Podocin R229Q in Genetic Predisposition to Glomerular Disease. J Am Soc Nephrol. 2022 Jan;33(1):138-154. doi: 10.1681/ASN.2020060858. Epub 2021 Dec 1. PMID: 34853150.
• Heeß A, Meyer AM, Becker I, Noetzel N, Verleysdonk J, Rarek M, Benzing T, Polidori MC (2021). The prognostic fingerprint of quality of life in older inpatients : Relationship to geriatric syndromes' and resources' profile. Z Gerontol Geriatr. 2022 Feb;55(1):38-43. English. doi: 10.1007/s00391-021-01978-5. Epub 2021 Oct 6. PMID: 34617144.
• Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T,Schermer B, Schwarz G, Burst V, Müller RU (2022). A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism. Transl Res. 2022 Feb 18:S1931-5244(22)00023-8. doi: 10.1016/j.trsl.2022.02.003. Epub ahead of print. PMID: 35189406. 
• Reusch B, Bartram MP, Dafinger C, Palacio-Escat N, Wenzel A, Fenton RA, Saez-Rodriguez J, Schermer B, Benzing T, Altmüller J, Beck BB, Rinschen MM (2022). MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells. J Proteomics. 2022 Feb 10;252:104424. doi: 10.1016/j.jprot.2021.104424. Epub 2021 Nov 12. PMID: 34775100. 
• Meyer AM, Pickert L, Heeß A, Becker I, Kurschat C, Bartram MP, Benzing T, Polidori MC (2022). Prognostic Signature of Chronic Kidney Disease in Advanced Age: Secondary Analysis from the InGAH Study with One-Year Follow-Up. Biomolecules. 2022 Mar 9;12(3):423. doi: 10.3390/biom12030423. PMID: 35327615; PMCID: PMC8946591.
• Hoyer-Allo KJR, Späth MR, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Brönneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler FC, Grundmann F, Hackl MJ, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2022). Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney Int. 2022 May 30:S0085-2538(22)00386-6. doi: 10.1016/j.kint.2022.04.033. Epub ahead of print. PMID: 35654224.
• Osterholt T, Gloistein C, Todorova P, Becker I, Arenskrieger K, Melka R, Koehler FC, Faust M, Wahlers T, Benzing T, Müller RU, Grundmann F, Burst V (2022). Preoperative Short-Term Restriction of Sulfur-Containing Amino Acid Intake for Prevention of Acute Kidney Injury After Cardiac Surgery: A Randomized, Controlled, Double-Blind, Translational Trial. J Am Heart Assoc. 2022 Sep 6;11(17):e025229. doi: 10.1161/JAHA.121.025229. Epub 2022 Sep 3. PMID: 36056721; PMCID: PMC9496445.
• Affeldt, P., Koehler, F.C., Brensing, K.A., Gies, M., Platen, E., Adam, V., Butt, L., Grundmann, F., Heger, E., Hinrichs, S., Kalisch, N., Oehm, S., Steger, G., Wirtz, M., Benzing, T., Stippel, D., Klein, F., Kurschat, C., Muller, R.U., and Di Cristanziano, V. (2022). Immune Response to Third and Fourth COVID-19 Vaccination in Hemodialysis Patients and Kidney Transplant Recipients. Viruses14. 10.3390/v14122646.
• Hagmann, H., Khayyat, N.H., Oezel, C., Papadakis, A., Kuczkowski, A., Benzing, T., Gulbins, E., Dryer, S., and Brinkkoetter, P.T. (2022). Paraoxonase 2 (PON2) Deficiency Reproduces Lipid Alterations of Diabetic and Inflammatory Glomerular Disease and Affects TRPC6 Signaling. Cells11. 10.3390/cells11223625.
• Kieckhofer, E., Slaats, G.G., Ebert, L.K., Albert, M.C., Dafinger, C., Kashkar, H., Benzing, T., and Schermer, B. (2022). Primary cilia suppress Ripk3-mediated necroptosis. Cell Death Discov8, 477. 10.1038/s41420-022-01272-2.
• Meyer, A.M., Bartram, M.P., Antczak, P., Becker, I., Benzing, T., and Polidori, M.C. (2022). A Tailored Discharge Program Improves Frailty and Mood in Patients Undergoing Usual Rehabilitative Care: A Randomized Controlled Trial. J Am Med Dir Assoc23, 1962 e1961-1962 e1913. 10.1016/j.jamda.2022.09.003.
• Rinschen, M.M., Palygin, O., El-Meanawy, A., Domingo-Almenara, X., Palermo, A., Dissanayake, L.V., Golosova, D., Schafroth, M.A., Guijas, C., Demir, F., Jaegers, J., Gliozzi, M.L., Xue, J., Hoehne, M., Benzing, T., Kok, B.P., Saez, E., Bleich, M., Himmerkus, N., Weisz, O.A., Cravatt, B.F., Kruger, M., Benton, H.P., Siuzdak, G., and Staruschenko, A. (2022). Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension. Nat Commun13, 4099. 10.1038/s41467-022-31670-0.

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Andreas Beyer

• Leote AC, Wu X, Beyer A (2022). Regulatory network-based imputation of dropouts in single-cell RNA sequencing data. PLoS Comput Biol. 2022 Feb 17;18(2):e1009849. doi: 10.1371/journal.pcbi.1009849. PMID: 35176023; PMCID: PMC8890719.
• Fraser HC, Kuan V, Johnen R, Zwierzyna M, Hingorani AD, Beyer A, Partridge L (2022). Biological mechanisms of aging predict age-related disease co-occurrence in patients. Aging Cell. 2022 Apr;21(4):e13524. doi: 10.1111/acel.13524. Epub 2022 Mar 8. PMID: 35259281; PMCID: PMC9009120. 
• Huth M, Santini L, Galimberti E, Ramesmayer J, Titz-Teixeira F, Sehlke R, Oberhuemer M, Stummer S, Herzog V, Garmhausen M, Romeike M, Chugunova A, Leesch F, Holcik L, Weipoltshammer K, Lackner A, Schoefer C, von Haeseler A, Buecker C, Pauli A, Ameres SL, Smith A, Beyer A, Leeb M (2022). NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation. Genes Dev. 2022 Mar 1;36(5-6):348-367. doi: 10.1101/gad.347690.120. Epub 2022 Mar 3. PMID: 35241478; PMCID: PMC8973849.

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Kasia Bozek

• Hanuscheck, N., Thalman, C., Domingues, M., Schmaul, S., Muthuraman, M., Hetsch, F., Ecker, M., Endle, H., Oshaghi, M., Martino, G., Kuhlmann, T., Bozek, K., van Beers, T., Bittner, S., von Engelhardt, J., Vogt, J., Vogelaar, C.F., and Zipp, F. (2022). Interleukin-4 receptor signaling modulates neuronal network activity. J Exp Med219. 10.1084/jem.20211887.

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Jens Brüning  

• Vesting AJ, Jais A, Klemm P, Steuernagel L, Wienand P, Fog-Tonnesen M, Hvid H, Schumacher AL, Kukat C, Nolte H, Georgomanolis T, Altmüller J, Pasparakis M, Schmidt A, Krüger M, Supprian MS, Waisman A, Straub BK, Raschzok N, Bernier M, Birkenfeld AL, Hövelmeyer N, Brüning JC, Wunderlich FT (2022). NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition.Mol Metab. 2022 Nov 7:101626. doi: 10.1016/j.molmet.2022.101626. Online ahead of print. PMID: 36356831
• Grieß K, Rieck M, Müller N, Karsai G, Hartwig S, Pelligra A, Hardt R, Schlegel C, Kuboth J, Uhlemeyer C, Trenkamp S, Jeruschke K, Weiß J, Peifer-Weiß L, Xu W, Cames S, Yi X, Cnop M, Beller M, Stark H, Reichert AS, Markgraf D, Wammers M, Häussinger D, Kuss O, Lehr S, Eizirik D, Lickert H, Lammert E, Roden M, Winter D, Al-Hasani H, Höglinger D, Hornemann T, Brüning JC, Belgardt BF. Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis. (2022) Nat. Cell. Biol. in press
• Gaziano I, Corneliussen S, Biglari N, Neuhaus R, Shen L, Sotelo-Hitschfeld T, Klemm P, Steuernagel L, De Solis AJ, Chen W, Wunderlich FT, Kloppenburg P, Brüning JC (2022).Dopamine-inhibited POMCDrd2+ neurons in the ARC acutely regulate feeding and body temperature. JCI Insight. 2022 Nov 8;7(21):e162753. doi: 10.1172/jci.insight.162753. PMID: 36345942 
• Steuernagel L, Lam BYH, Klemm P, Dowsett GKC, Bauder CA, Tadross JA, Hitschfeld TS, Del Rio Martin A, Chen W, de Solis AJ, Fenselau H, Davidsen P, Cimino I, Kohnke SN, Rimmington D, Coll AP, Beyer A, Yeo GSH, Brüning JC (2022). HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus.Nat Metab. 2022 Oct;4(10):1402-1419. doi: 10.1038/s42255-022-00657-y. Epub 2022 Oct 20. PMID: 36266547 
• Fulzele K, Riddle RC, DiGirolamo DJ, Cao X, Wan C, Chen D, Faugere MC, Aja S, Hussain MA, Brüning JC, Clemens TL (2022). Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition. Cell. 2022 Feb 17;185(4):746. doi: 10.1016/j.cell.2022.01.016. PMID: 35180388 Free PMC article. 
• Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery.Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.
• Hoyer-Allo KJR, Späth MR, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Brönneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler FC, Grundmann F, Hackl MJ, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2022). Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney Int. 2022 May 30:S0085-2538(22)00386-6. doi: 10.1016/j.kint.2022.04.033. Epub ahead of print. PMID: 35654224. 
• Hammerschmidt P, Brüning JC (2022). Contribution of specific ceramides to obesity-associated metabolic diseases. Cell Mol Life Sci. 2022 Jul 5;79(8):395. doi: 10.1007/s00018-022-04401-3. PMID: 35789435; PMCID: PMC9252958.
• Ramírez S, Haddad-Tóvolli R, Radosevic M, Toledo M, Pané A, Alcolea D, Ribas V, Milà-Guasch M, Pozo M, Obri A, Eyre E, Gómez-Valadés AG, Chivite I, Van Eeckhout T, Zalachoras I, Altirriba J, Bauder C, Imbernón M, Garrabou G, Garcia-Ruiz C, Nogueiras R, Soto D, Gasull X, Sandi C, Brüning JC, Fortea J, Jiménez A, Fernández-Checa JC, Claret M (2022). Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders. Cell Metab. 2022 Feb 1;34(2):269-284.e9. doi: 10.1016/j.cmet.2021.12.023. PMID: 35108514; PMCID: PMC8815774.
• Hanssen R, Thanarajah SE, Tittgemeyer M, Brüning JC (2022). Obesity - A Matter of Motivation? Exp Clin Endocrinol Diabetes. 2022 Feb 18. doi: 10.1055/a-1749-4852. Epub ahead of print. PMID: 35181879.
• Matsushita M, Awazawa M, Kobayashi N, Ikushima YM, Soeda K, Tamura-Nakano M, Muratani M, Kobayashi K, Blüher M, Brüning JC, Ueki K (2022). An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance.Cell Chem Biol. 2022 Apr 21;29(4):680-689.e6. doi: 10.1016/j.chembiol.2021.12.008. Epub 2022 Jan 4. PMID: 34986326.
• Jais A, Brüning JC (2022). Arcuate Nucleus-Dependent Regulation of Metabolism-Pathways to Obesity and Diabetes Mellitus. Endocr Rev. 2022 Mar 9;43(2):314-328. doi: 10.1210/endrev/bnab025. PMID: 34490882; PMCID: PMC8905335. 
• Lippert RN, Brüning JC (2022) Maternal Metabolic Programming of the Developing Central Nervous System: Unified Pathways to Metabolic and Psychiatric Disorders.Biol Psychiatry. 2022 May 15;91(10):898-906. doi: 10.1016/j.biopsych.2021.06.002. Epub 2021 Jun 8. PMID: 34330407
• Willenborg, S., Sanin, D.E., Jais, A., Ding, X., Ulas, T., Nuchel, J., Popovic, M., MacVicar, T., Langer, T., Schultze, J.L., Roers, A., Pearce, E.J., Brüning, J.C., Trifunovic, A., and Eming, S.A. (2022). Metabolic reprogramming coordinates dynamics of myeloid cell function in skin repair. Exp Dermatol31, E62-E62.
• Willenborg, S., Sanin, D.E., Jais, A., Schultze, J.L., Roers, A., Pearce, E.J., Brüning, J.C., Trifunovic, A., and Eming, S.A. (2022). Healthy repair of injured skin requires mitochondrial repurposing in wound macrophages. J Invest Dermatol142, S235-S235.

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Filipe Cabreiro

• Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.

Oliver Cornely

• Seidel D, Simon M, Sprute R, Lubnow M, Evert K, Speer C, Seeßle J, Khatamzas E, Merle U, Behrens C, Blau IW, Enghard P, Haas CS, Steinmann J, Kurzai O, Cornely OA (2022). Results from a national survey on COVID-19-associated mucormycosis in Germany: 13 patients from six tertiary hospitals. Mycoses. 2022 Jan;65(1):103-109. doi: 10.1111/myc.13379. Epub 2021 Nov 16. PMID: 34655486; PMCID: PMC8662289.
• Vehreschild MJGT, Ducher A, Louie T, Cornely OA, Feger C, Dane A, Varastet M, Vitry F, de Gunzburg J, Andremont A, Mentré F, Wilcox MH (2022).An open randomized multicentre Phase 2 trial to assess the safety of DAV132 and its efficacy to protect gut microbiota diversity in hospitalized patients treated with fluoroquinolones. J Antimicrob Chemother. 2022 Jan 7:dkab474. doi: 10.1093/jac/dkab474. Epub ahead of print. PMID: 35016205.
• Hoenigl M, Seidel D, Carvalho A, Rudramurthy SM, Arastehfar A, Gangneux JP, Nasir N, Bonifaz A, Araiza J, Klimko N, Serris A, Lagrou K, Meis JF, Cornely OA, Perfect JR, White PL, Chakrabarti A; ECMM and ISHAM collaborators (2022). The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries. Lancet Microbe. 2022 Jan 25. doi: 10.1016/S2666-5247(21)00237-8. Epub ahead of print. PMID: 35098179; PMCID: PMC8789240.
• Henze L, Buhl C, Sandherr M, Cornely OA, Heinz WJ, Khodamoradi Y, Kiderlen TR, Koehler P, Seidler A, Sprute R, Schmidt-Hieber M, von Lilienfeld-Toal M (2022). Management of herpesvirus reactivations in patients with solid tumours and hematologic malignancies: update of the Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO) on herpes simplex virus type 1, herpes simplex virus type 2, and varicella zoster virus. Ann Hematol. 2022 Mar;101(3):491-511. doi: 10.1007/s00277-021-04746-y. Epub 2022 Jan 7. PMID: 34994811; PMCID: PMC8810475.
• Blankenheim Y, Salmanton-García J, Seifert H, Cornely OA, Koehler P (2022). Attributable mortality of candidemia at a German tertiary hospital from 1997 to 2001 before the introduction of echinocandins. Mycoses. 2022 Feb;65(2):211-221. doi: 10.1111/myc.13406. Epub 2021 Dec 8. PMID: 34847247.
• Jeck J, Jakobs F, Kron A, Franz J, Cornely OA, Kron F (2022). A cost of illness study of COVID-19 patients and retrospective modelling of potential cost savings when administering remdesivir during the pandemic "first wave" in a German tertiary care hospital. Infection. 2022 Feb;50(1):191-201. doi: 10.1007/s15010-021-01685-8. Epub 2021 Aug 18. PMID: 34406606; PMCID: PMC8371942.
• Bassetti M, Vena A, Giacobbe DR, Trucchi C, Ansaldi F, Antonelli M, Adamkova V, Alicino C, Almyroudi MP, Atchade E, Azzini AM, Brugnaro P, Carannante N, Peghin M, Berruti M, Carnelutti A, Castaldo N, Corcione S, Cortegiani A, Dimopoulos G, Dubler S, García-Garmendia JL, Girardis M, Cornely OA, Ianniruberto S, Kullberg BJ, Lagrou K, Lebihan C, Luzzati R, Malbrain M, Merelli M, Marques AJ, Martin-Loeches I, Mesini A, Paiva JA, Raineri SM, Rautemaa-Richardson R, Schouten J, Spapen H, Tasioudis P, Timsit JF, Tisa V, Tumbarello M, Van den Berg CHSB, Veber B, Venditti M, Voiriot G, Wauters J, Zappella N, Montravers P; from the Study Group for Infections in Critically Ill Patients (ESGCIP) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) (2022). Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study. Infect Dis Ther. 2022 Apr;11(2):827-840. doi: 10.1007/s40121-021-00585-6. Epub 2022 Feb 19. PMID: 35182353; PMCID: PMC8960530.
• Driemeyer C, Falci DR, Hoenigl M, Cornely OA, Chakrabarti A, Gangneux JP, Segal E, Jürna-Ellam M, Matos T, Meis JF, Perfect JR, Arsenijevic VA, Mares M, Serban DE, Pasqualotto AC (2022). The current state of Clinical Mycology in Eastern and South-Eastern Europe. Med Mycol. 2022 Mar 22;60(4):myac017. doi: 10.1093/mmy/myac017. PMID: 35195256.
• Jeck J, Jakobs F, Kron A, Cornely OA, Kron F (2022). Retrospective modelling of hospital bed capacities associated with the administration of remdesivir during the first wave of COVID-19 in a German metropolitan city. J Antimicrob Chemother. 2022 Feb 23;77(3):753-757. doi: 10.1093/jac/dkab432. PMID: 34849943; PMCID: PMC8690174.
• Sprute R, Bethe U, Chen SC, Cornely OA (2022). EQUAL Trichosporon Score 2022: an ECMM score to measure QUALity of the clinical management of invasive Trichosporon infections. J Antimicrob Chemother. 2022 Mar 23:dkac085. doi: 10.1093/jac/dkac085. Epub ahead of print. PMID: 35325146.
• Giacobbe DR, Prattes J, Wauters J, Dettori S, Signori A, Salmanton-García J, Maertens J, Bourgeois M, Reynders M, Rutsaert L, Van Regenmortel N, Lormans P, Feys S, Klimko N, Shadrivova O, Cornely OA, Rautemaa-Richardson R, Koehler P, Lagrou K, Bassetti M, Hoenigl M; ECMM-CAPA Study Group (2022).Prognostic Impact of Bronchoalveolar Lavage Fluid Galactomannan and Aspergillus Culture Results on Survival in COVID-19 Intensive Care Unit Patients: a Post Hoc Analysis from the European Confederation of Medical Mycology (ECMM) COVID-19-Associated Pulmonary Aspergillosis Study. J Clin Microbiol. 2022 Apr 20;60(4):e0229821. doi: 10.1128/jcm.02298-21. Epub 2022 Mar 24. PMID: 35321555; PMCID: PMC9020339.
• Pagano L, Salmanton-García J, Marchesi F, López-García A, Lamure S, Itri F, Gomes-Silva M, Dragonetti G, Falces-Romero I, van Doesum J, Sili U, Labrador J, Calbacho M, Bilgin YM, Weinbergerová B, Serrano L, Ribera-Santa Susana JM, Malak S, Loureiro-Amigo J, Glenthøj A, Córdoba-Mascuñano R, Nunes-Rodrigues R, González-López TJ, Karlsson LK, Jiménez-Lorenzo MJ, Hernández-Rivas JÁ, Jaksic O, Ráčil Z, Busca A, Corradini P, Hoenigl M, Klimko N, Koehler P, Pagliuca A, Passamonti F, Cornely OA (2022).COVID-19 in vaccinated adult patients with hematological malignancies: preliminary results from EPICOVIDEHA. Blood. 2022 Mar 10;139(10):1588-1592. doi: 10.1182/blood.2021014124. PMID: 34748627; PMCID: PMC8577877.
• Dalimot JJ, Smith IMC, Gerkrath J, Hartmann S, Cornely OA, Lee SC, Heitman J, Rickerts V (2022). Identification of Mucormycosis by Fluorescence In Situ Hybridization Targeting Ribosomal RNA in Tissue Samples. J Fungi (Basel). 2022 Mar 11;8(3):289. doi: 10.3390/jof8030289. PMID: 35330291; PMCID: PMC8949899.
• Bonifacius A, Tischer-Zimmermann S, Santamorena MM, Mausberg P, Schenk J, Koch S, Barnstorf-Brandes J, Gödecke N, Martens J, Goudeva L, Verboom M, Wittig J, Maecker-Kolhoff B, Baurmann H, Clark C, Brauns O, Simon M, Lang P, Cornely OA, Hallek M, Blasczyk R, Seiferling D, Köhler P, Eiz-Vesper B (2022). Rapid Manufacturing of Highly Cytotoxic Clinical-Grade SARS-CoV-2-specific T Cell Products Covering SARS-CoV-2 and Its Variants for Adoptive T Cell Therapy. Front Bioeng Biotechnol. 2022 Apr 4;10:867042. doi: 10.3389/fbioe.2022.867042. PMID: 35480981; PMCID: PMC9036989.
• Goebel H, Koeditz B, Huerta M, Kameri E, Nestler T, Kamphausen T, Friemann J, Hamdorf M, Ohrmann T, Koehler P, Cornely OA, Montesinos-Rongen M, Nicol D, Schorle H, Boor P, Quaas A, Pallasch C, Heidenreich A, von Brandenstein M (2022). COVID-19 Infection Induce miR-371a-3p Upregulation Resulting in Influence on Male Fertility. Biomedicines. 2022 Apr 6;10(4):858. doi: 10.3390/biomedicines10040858. PMID: 35453608; PMCID: PMC9033010.
• Stemler J, de Jonge N, Skoetz N, Sinkó J, Brüggemann RJ, Busca A, Ben-Ami R, Ráčil Z, Piechotta V, Lewis R, Cornely OA (2022). Antifungal prophylaxis in adult patients with acute myeloid leukaemia treated with novel targeted therapies: a systematic review and expert consensus recommendation from the European Hematology Association. Lancet Haematol.2022 May;9(5):e361-e373. doi: 10.1016/S2352-3026(22)00073-4. PMID: 35483397.
• Koehler P, von Stillfried S, Garcia Borrega J, Fuchs F, Salmanton-García J, Pult F, Böll B, Eichenauer DA, Shimabukuro-Vornhagen A, Kurzai O, Boor P, Kochanek M, Cornely OA(2022). Aspergillus tracheobronchitis in COVID-19 patients with acute respiratory distress syndrome: a cohort study. Eur Respir J. 2022 May 5;59(5):2103142. doi: 10.1183/13993003.03142-2021. PMID: 35144992; PMCID: PMC9068972.
• Keutmann M, Hermes G, Meinberger D, Roth A, Stemler J, Cornely OA, Klatt AR, Streichert T (2022). The ratio of serum LL-37 levels to blood leucocyte count correlates with COVID-19 severity. Sci Rep. 2022 Jun 8;12(1):9447. doi: 10.1038/s41598-022-13260-8. PMID: 35676519; PMCID: PMC9175165.
• Salmanton-García J, Stewart FA, Heringer S, Koniordou M, Álvarez-Barco E, Argyropoulos CD, Themistocleous SC, Valle-Simón P, Spivak O, Součková L, Merakou C, Amélia Mendonça M, Joanna Davis R, Maria Azzini A, Askling HH, Vene S, Van Damme P, Steinbach A, Shiamakkides G, Seidel D, Olesen OF, Noula E, Macken A, Luís C, Leckler J, Launay O, Isitt C, Hellemans M, Frías-Iniesta J, Di Marzo R, Carcas AJ, Boustras G, Borobia AM, Barta I, Albus K, Akova M, Ochando J, Cohen-Kandli M, Jane Cox R, Husa P, Jancoriene L, Mallon P, Marques L, Mellinghoff SC, Nauclér P, Tacconelli E, Tóth K, Zaoutis TE, Zeitlinger M, Cornely OA, Pana ZD; VACCELERATE consortium (2022). VACCELERATE Volunteer Registry: A European study participant database to facilitate clinical trial enrolment. Vaccine. 2022 Jul 29;40(31):4090-4097. doi: 10.1016/j.vaccine.2022.05.022. Epub 2022 Jun 2. PMID: 35659449; PMCID: PMC9159788.
• Bloos F, Held J, Kluge S, Simon P, Kogelmann K, de Heer G, Kuhn SO, Jarczak D, Motsch J, Hempel G, Weiler N, Weyland A, Drüner M, Gründling M, Meybohm P, Richter D, Jaschinski U, Moerer O, Günther U, Schädler D, Weiss R, Putensen C, Castellanos I, Kurzai O, Schlattmann P, Cornely OA, Bauer M, Thomas-Rüddel D; SepNet Study Group (2022). (1 → 3)-β-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial. Intensive Care Med. 2022 Jul;48(7):865-875. doi: 10.1007/s00134-022-06733-x. Epub 2022 Jun 16. PMID: 35708758; PMCID: PMC9273538.
• Blennow O, Salmanton-García J, Nowak P, Itri F, Van Doesum J, López-García A, Farina F, Jaksic O, Pinczés LI, Bilgin YM, Falces-Romero I, Jiménez M, Ormazabal-Vélez I, Weinbergerová B, Duléry R, Stojanoski Z, Lahmer T, Fernández N, Hernández-Rivas JÁ, Petzer V, De Jonge N, Glenthøj A, De Ramón C, Biernat MM, Fracchiolla N, Aujayeb A, Van Praet J, Schönlein M, Méndez GA, Cattaneo C, Guidetti A, Sciumè M, Ammatuna E, Cordoba R, García-Poutón N, Gräfe S, Cabirta A, Wolf D, Nordlander A, García-Sanz R, Delia M, Berg Venemyr C, Brones C, Di Blasi R, De Kort E, Meers S, Lamure S, Serrano L, Merelli M, Coppola N, Bergantim R, Besson C, Kohn M, Petiti J, Garcia-Vidal C, Dargenio M, Danion F, Machado M, Bailén-Almorox R, Hoenigl M, Dragonetti G, Chai LYA, Kho CS, Bonanni M, Liévin R, Marchesi F, Cornely OA, Pagano L (2022). Outcome of infection with omicron SARS-CoV-2 variant in patients with hematological malignancies: An EPICOVIDEHA survey report. Am J Hematol. 2022 Aug;97(8):E312-E317. doi: 10.1002/ajh.26626. Epub 2022 Jun 28. PMID: 35702878.
• Van Braeckel E, Page I, Davidsen JR, Laursen CB, Agarwal R, Alastruey-Izquierdo A, Barac A, Cadranel J, Chakrabarti A, Cornely OA, Denning DW, Flick H, Gangneux JP, Godet C, Hayashi Y, Hennequin C, Hoenigl M, Irfan M, Izumikawa K, Koh WJ, Kosmidis C, Lange C, Lamprecht B, Laurent F, Munteanu O, Oladele R, Patterson TF, Watanabe A, Salzer HJF; CPAnet (2022). Treatment outcome definitions in chronic pulmonary aspergillosis: a CPAnet consensus statement. Eur Respir J. 2022 Jun 9;59(6):2102950. doi: 10.1183/13993003.02950-2021. PMID: 35236726.
• Cornely ME, Hasenberg T, Cornely OA, Ure C, Hettenhausen C, Schmidt J (2022). Persistent lipedema pain in patients after bariatric surgery: a case series of 13 patients. Surg Obes Relat Dis. 2022 May;18(5):628-633. doi: 10.1016/j.soard.2021.12.027. Epub 2022 Jan 7. PMID: 35144895.
• Lamure S, Salmanton-García J, Robin-Marieton E, Jaksic O, Kohn M, Marchesi F, Marchetti M, El-Ashwah S, Demirkan F, Valković T, Fernández N, Tisi MC, Stojanoski Z, Seval GC, Ilhan O, Prezioso L, Merelli M, López-García A, Ledoux MP, Kulasekararaj A, González-López TJ, Gomes da Silva M, Emarah Z, Duarte RF, Cattaneo C, Blennow O, Bilgin YM, Bergantim R, Batinić J, Cordoba R, Essame J, Nordlander A, Nunes Rodrigues R, Sacchi MV, Zompi S, Busca A, Corradini P, Hoenigl M, Klimko N, Koehler P, Pagliuca A, Passamonti F, Duléry R, Cornely OA, Besson C, Pagano L (2022). COVID-19 and hairy-cell leukemia: an EPICOVIDEHA survey. Blood Adv. Jul 12;6(13):3870-3874. doi: 10.1182/bloodadvances.2022007357. PMID: 35500220
• Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, Ortiz AB, Salazar A, Chercoles AG, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A, Holten AR, Mayer A, Bandera A, Cherubini A, Protti A, Aghemo A, Gerussi A, Ramirez A, Braun A, Nebel A, Barreira A, Lleo A, Teles A, Kildal AB, Biondi A, Caballero-Garralda A, Ganna A, Gori A, Glück A, Lind A, Tanck A, Hinney A, Nolla AC, Fracanzani AL, Peschuck A, Cavallero A, Dyrhol-Riise AM, Ruello A, Julià A, Muscatello A, Pesenti A, Voza A, Rando-Segura A, Solier A, Schmidt A, Cortes B, Mateos B, Nafria-Jimenez B, Schaefer B, Jensen B, Bellinghausen C, Maj C, Ferrando C, Horra C, Quereda C, Skurk C, Thibeault C, Scollo C, Herr C, Spinner CD, Gassner C, Lange C, Hu C, Paccapelo C, Lehmann C, Angelini C, Cappadona C, Azuure C; COVICAT study group, Aachen Study (COVAS), Bianco C, Cea C, Sancho C, Hoff DAL, Galimberti D, Prati D, Haschka D, Jiménez D, Pestaña D, Toapanta D, Muñiz-Diaz E, Azzolini E, Sandoval E, Binatti E, Scarpini E, Helbig ET, Casalone E, Urrechaga E, Paraboschi EM, Pontali E, Reverter E, Calderón EJ, Navas E, Solligård E, Contro E, Arana-Arri E, Aziz F, Garcia F, Sánchez FG, Ceriotti F, Martinelli-Boneschi F, Peyvandi F, Kurth F, Blasi F, Malvestiti F, Medrano FJ, Mesonero F, Rodriguez-Frias F, Hanses F, Müller F, Hemmrich-Stanisak G, Bellani G, Grasselli G, Pezzoli G, Costantino G, Albano G, Cardamone G, Bellelli G, Citerio G, Foti G, Lamorte G, Matullo G, Baselli G, Kurihara H, Neb H, My I, Kurth I, Hernández I, Pink I, Rojas I, Galván-Femenia I, Holter JC, Afset JE, Heyckendorf J, Kässens J, Damås JK, Rybniker J, Altmüller J, Ampuero J, Martín J, Erdmann J, Banales JM, Badia JR, Dopazo J, Schneider J, Bergan J, Barretina J, Walter J, Quero JH, Goikoetxea J, Delgado J, Guerrero JM, Fazaal J, Kraft J, Schröder J, Risnes K, Banasik K, Müller KE, Gaede KI, Garcia-Etxebarria K, Tonby K, Heggelund L, Izquierdo-Sanchez L, Bettini LR, Sumoy L, Sander LE, Lippert LJ, Terranova L, Nkambule L, Knopp L, Gustad LT, Garbarino L, Santoro L, Téllez L, Roade L, Ostadreza M, Intxausti M, Kogevinas M, Riveiro-Barciela M, Berger MM, Schaefer M, Niemi MEK, Gutiérrez-Stampa MA, Carrabba M, Figuera Basso ME, Valsecchi MG, Hernandez-Tejero M, Vehreschild MJGT, Manunta M, Acosta-Herrera M, D'Angiò M, Baldini M, Cazzaniga M, Grimsrud MM, Cornberg M, Nöthen MM, Marquié M, Castoldi M, Cordioli M, Cecconi M, D'Amato M, Augustin M, Tomasi M, Boada M, Dreher M, Seilmaier MJ, Joannidis M, Wittig M, Mazzocco M, Ciccarelli M, Rodríguez-Gandía M, Bocciolone M, Miozzo M, Ayo NI, Blay N, Chueca N, Montano N, Braun N, Ludwig N, Marx N, Martínez N; Norwegian SARS-CoV-2 Study group, Cornely OA, Witzke O, Palmieri O; Pa Study Group, Faverio P, Preatoni P, Bonfanti P, Omodei P, Tentorio P, Castro P, Rodrigues PM, España PP, Hoffmann P, Rosenstiel P, Schommers P, Suwalski P, Pablo R, Ferrer R, Bals R, Gualtierotti R, Gallego-Durán R, Nieto R, Carpani R, Morilla R, Badalamenti S, Haider S, Ciesek S, May S, Bombace S, Marsal S, Pigazzini S, Klein S, Pelusi S, Wilfling S, Bosari S, Volland S, Brunak S, Raychaudhuri S, Schreiber S, Heilmann-Heimbach S, Aliberti S, Ripke S, Dudman S, Wesse T, Zheng T; STORM Study group, The Humanitas Task Force, The Humanitas Gavazzeni Task Force, Bahmer T, Eggermann T, Illig T, Brenner T, Pumarola T, Feldt T, Folseraas T, Cejudo TG, Landmesser U, Protzer U, Hehr U, Rimoldi V, Monzani V, Skogen V, Keitel V, Kopfnagel V, Friaza V, Andrade V, Moreno V, Albrecht W, Peter W, Poller W, Farre X, Yi X, Wang X, Khodamoradi Y, Karadeniz Z, Latiano A, Goerg S, Bacher P, Koehler P, Tran F, Zoller H, Schulte EC, Heidecker B, Ludwig KU, Fernández J, Romero-Gómez M, Albillos A, Invernizzi P, Buti M, Duga S, Bujanda L, Hov JR, Lenz TL, Asselta R, Cid R, Valenti L, Karlsen TH, Cáceres M, Franke A (2022). Detailed stratified GWAS analysis for severe COVID-19 in four European populations. Hum Mol Genet. Jul 15:ddac158. doi: 10.1093/hmg/ddac158. Epub ahead of print. PMID: 35848942.
• Zhang J, Zhang Y, Wu D, Cao G, Hamed K, Desai A, Aram JA, Guo X, Fayyad R, Cornely OA (2022). Plain language summary: use of isavuconazole in Chinese patients with an invasive fungal disease. Future Microbiol. Oct;17:1203-1206. doi: 10.2217/fmb-2022-0093. Epub 2022 Aug 2. PMID: 35916057.
• Hoenigl M, Sprute R, Arastehfar A, Perfect JR, Lass-Flörl C, Bellmann R, Prattes J, Thompson GR 3rd, Wiederhold NP, Al Obaidi MM, Willinger B, Arendrup MC, Koehler P, Oliverio M, Egger M, Schwartz IS, Cornely OA, Pappas PG, Krause R (2022). Invasive candidiasis: investigational drugs in the clinical development pipeline and mechanisms of action. Expert Opin Investig Drugs. Aug;31(8):795-812. doi: 10.1080/13543784.2022.2086120. Epub Jun 15. PMID: 35657026; PMCID: PMC9339492.
• Grothe J, Sprute R, Cornely OA (2022). Comment on: Nephrotoxicity of continuous amphotericin B in critically ill patients with abdominal sepsis: a retrospective analysis with propensity score matching. J Antimicrob Chemother. Jul 28;77(8):2308-2309. doi: 10.1093/jac/dkac098. PMID: 35325191; PMCID: PMC9333405.
• Sal E, Stemler J, Salmanton-García J, Falces-Romero I, Kredics L, Meyer E, Würstl B, Lass-Flörl C, Racil Z, Klimko N, Cesaro S, Kindo AJ, Wisplinghoff H, Koehler P, Cornely OA, Seidel D (2022). Invasive Trichoderma spp. infections: clinical presentation and outcome of cases from the literature and the FungiScope® registry. J Antimicrob Chemother. Sep 30;77(10):2850-2858. doi: 10.1093/jac/dkac235. PMID: 35929089; PMCID: PMC9525085.
• Mellinghoff SC, Bruns C, Al-Monajjed R, Cornely FB, Grosheva M, Hampl JA, Jakob C, Koehler FC, Lechmann M, Maged B, Otto-Lambertz C, Rongisch R, Rutz J, Salmanton-Garcia J, Schlachtenberger G, Stemler J, Vehreschild J, Wülfing S, Cornely OA, Liss BJ (2022). Harmonized procedure coding system for surgical procedures and analysis of surgical site infections (SSI) of five European countries. BMC Med Res Methodol. Aug 12;22(1):225. doi: 10.1186/s12874-022-01702-w. PMID: 35962320; PMCID: PMC9374282.
• Saggau C, Martini GR, Rosati E, Meise S, Messner B, Kamps AK, Bekel N, Gigla J, Rose R, Voß M, Geisen UM, Reid HM, Sümbül M, Tran F, Berner DK, Khodamoradi Y, Vehreschild MJGT, Cornely OA, Koehler P, Krumbholz A, Fickenscher H, Kreuzer O, Schreiber C, Franke A, Schreiber S, Hoyer B, Scheffold A, Bacher P (2022). The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination. Immunity. Oct 11;55(10):1924-1939.e5. doi: 10.1016/j.immuni.2022.08.003. Epub Aug 12. PMID: 35985324; PMCID: PMC9372089.
• Grothe JH, Cornely OA, Salmanton-García J; VACCELERATE consortium (2022). Monkeypox diagnostic and treatment capacity at epidemic onset: A VACCELERATE online survey. J Infect Public Health. Aug 27;15(10):1043-1046. doi: 10.1016/j.jiph.2022.08.008. Epub ahead of print. PMID: 36049256; PMCID: PMC9420010.
• Cattaneo, C., Salmanton-Garcia, J., Marchesi, F., El-Ashwah, S., Itri, F., Weinbergerova, B., Da Silva, M.G., Dargenio, M., Davila-Valls, J., Martin-Perez, S., Farina, F., Van Doesum, J., Valkovic, T., Besson, C., Poulsen, C.B., Lopez-Garcia, A., Zak, P., Schonlein, M., Piukovics, K., Jaksic, O., Cabirta, A., Ali, N., Sili, U., Fracchiolla, N., Dragonetti, G., Adzic-Vukicevic, T., Marchetti, M., Machado, M., Glenthoj, A., Finizio, O., Demirkan, F., Blennow, O., Tisi, M.C., Omrani, A.S., Navratil, M., Racil, Z., Novak, J., Magliano, G., Jimenez, M., Garcia-Vidal, C., Erben, N., Del Principe, M.I., Buquicchio, C., Bergantim, R., Batinic, J., Al-Khabori, M., Verga, L., Szotkowski, T., Samarkos, M., Ormazabal-Velez, I., Meers, S., Maertens, J., Pinczes, L.I., Hoenigl, M., Drgona, L., Cuccaro, A., Bilgin, Y.M., Aujayeb, A., Rahimli, L., Grafe, S., Sciume, M., Mladenovic, M., Colak, G.M., Sacchi, M.V., Nordlander, A., Venemyr, C.B., Hanakova, M., Garcia-Pouton, N., Emarah, Z., Zambrotta, G.P.M., Rodrigues, R.N., Cordoba, R., Mendez, G.A., Biernat, M.M., Cornely, O.A., and Pagano, L. (2022). Simultaneous Onset of Haematological Malignancy and COVID: An Epicovideha Survey. Cancers14. ARTN 5530. 10.3390/cancers14225530.
• Classen, A.Y., Henze, L., von Lilienfeld-Toal, M., Maschmeyer, G., Sandherr, M., Duran, G.L., Alakel, N., Christopeit, M., Krause, S.W., Mayer, K., Neumann, S., Cornely, O.A., Penack, O., Weissinger, F., Wolf, H.H., and Vehreschild, J.J. (2022). Prophylaxis of bacterial Infections and Pneumocystis jirovecii pneumonia in Female Patients with hematological and oncological Diseases: Updated Guideline of the Working Group on Infections (AGIHO) of the German Society for Hematology and Oncology (DGHO). Oncol Res Treat45, 158-158.
• Cornely, O.A., Gachot, B., Akan, H., Bassetti, M., Uzun, O., Kibbler, C., Marchetti, O., de Burghgraeve, P., Ramadan, S., Pylkkanen, L., Ameye, L., Paesmans, M., Donnelly, J.P., and Grp, E.I.D. (2022). Epidemiology and Outcome of Fungemia in a Cancer Cohort of the Infectious Diseases Group (IDG) of the European Organization for Research and Treatment of Cancer (EORTC 65031) (vol 61, pg 324, 2015). Clin Infect Dis74, 1892-1892. 10.1093/cid/ciac144.
• Driemeyer, C., Falci, D.R., Oladele, R.O., Bongomin, F., Ocansey, B.K., Govender, N.P., Hoenigl, M., Gangneux, J.P., Lass-Florl, C., Cornely, O.A., Alanio, A., Guinea, J., Morrissey, C.O., Rautemaa-Richardson, R., Chakrabarti, A., Meis, J.F., Bruns, C., Stemler, J., and Pasqualotto, A.C. (2022). The current state of clinical mycology in Africa: a European Confederation of Medical Mycology and International Society for Human and Animal Mycology survey. Lancet Microbe3, E464-E470. 10.1016/S2666-5247(21)00190-7.
• Egger, M., Honigl, M., Salmanton--Garcia, J., Arendrup, M.C., Kohler, P., Gangneux, J.P., Bicanic, T., Arikan--Akdagli, S., Lass-Florl, C., Prattes, J., Willinger, B., Steinmann, J., Seufert, R., Trauth, J., Scharmann, U., Khanna, N., Adam, K.M., Meijer, E., and Cornely, O.A. (2022). Impact of Guideline adherence on outcome in Candidemia: Results from the ECMM Candida III multinational European study. Mycoses65, 11-12.
• Hoenigl, M., Lewis, R., van de Veerdonk, F.L., Verweij, P.E., and Cornely, O.A. (2022). Liposomal amphotericin B-the future. J Antimicrob Chemoth77, 21-34. 10.1093/jac/dkac353.
• Infante, M.S., Salmanton-Garcia, J., Fernandez-Cruz, A., Marchesi, F., Jaksic, O., Weinbergerova, B., Besson, C., Duarte, R.F., Itri, F., Valkovic, T., Szotkovski, T., Busca, A., Guidetti, A., Glenthoj, A., Collins, G.P., Bonuomo, V., Sili, U., Seval, G.C., Machado, M., Cordoba, R., Blennow, O., Abu-Zeinah, G., Lamure, S., Kulasekararaj, A., Falces-Romero, I., Cattaneo, C., Van Doesum, J., Piukovics, K., Omrani, A.S., Magliano, G., Ledoux, M.P., de Ramon, C., Cabirta, A., Verga, L., Lopez-Garcia, A., Da Silva, M.G., Stojanoski, Z., Meers, S., Lahmer, T., Martin-Perez, S., Davila-Vals, J., Van Praet, J., Samarkos, M., Bilgin, Y.M., Karlsson, L.K., Batinic, J., Nordlander, A., Schonlein, M., Hoenigl, M., Racil, Z., Mladenovic, M., Hanakova, M., Zambrotta, G.P.M., De Jonge, N., Adzic-Vukicevic, T., Nunes-Rodrigues, R., Prezioso, L., Navratil, M., Marchetti, M., Cuccaro, A., Calbacho, M., Giordano, A., Cornely, O.A., Hernandez-Rivas, J.A., and Pagano, L. (2022). B-cell malignancies treated with targeted drugs and SARS-CoV-2 infection: A European Hematology Association Survey (EPICOVIDEHA). Front Oncol12. ARTN 992137. 10.3389/fonc.2022.992137.
• Mellinghoff, S.C., Thelen, M., Bruns, C., Garcia-Marquez, M., Hartmann, P., Lammertz, T., Lehmann, J., Nowag, A., Stemler, J., Wennhold, K., Cornely, O.A., Von Bergwelt-Baildon, M.S., and Schlosser, H.A. (2022). T-cells of invasive candidiasis patients show patterns of T-cell-exhaustion suggesting checkpoint blockade as treatment option. J Infection84, 237-247. 10.1016/j.jinf.2021.12.009.
• Murton, M., Drane, E., Jarrett, J., Cornely, O.A., and Soriano, A. (2022). Remdesivir-related cost-effectiveness and cost and resource use evidence in COVID-19: a systematic review. Infection. 10.1007/s15010-022-01930-8.
• Neuhann, J.M., Stemler, J., Carcas, A., Frias-Iniesta, J., Bethe, U., Heringer, S., Tischmann, L., Zarrouk, M., Cuppers, A., Konig, F., Posch, M., and Cornely, O.A. (2022). A multinational, phase 2, randomised, adaptive protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines in adults >= 75 already vaccinated against SARS-CoV-2 (EU-COVAT-1-AGED): a trial conducted within the VACCELERATE network. Trials23. ARTN 865. 10.1186/s13063-022-06791-y.
• Piechotta, V., Mellinghoff, S.C., Hirsch, C., Brinkmann, A., Iannizzi, C., Kreuzberger, N., Adams, A., Monsef, I., Stemler, J., Cornely, O.A., Brockelmann, P.J., and Skoetz, N. (2022). Effectiveness, immunogenicity, and safety of COVID-19 vaccines for individuals with hematological malignancies: a systematic review. Blood Cancer J12. ARTN 86. 10.1038/s41408-022-00684-8.
• Prattes, J., Wauters, J., Giacobbe, D.R., Salmanton-Garcia, J., Maertens, J., Bourgeois, M., Reynders, M., Rutsaert, L., Van Regenmortel, N., Lormans, P., Feys, S., Reisinger, A.C., Cornely, O.A., Lahmer, T., Valerio, M., Delhaes, L., Jabeen, K., Steinmann, J., Chamula, M., Bassetti, M., Hatzl, S., Rautemaa-Richardson, R., Koehler, P., Lagrou, K., Hoenigl, M., and Grp, E.-C.S. (2022). Risk factors and outcome of pulmonary aspergillosis in critically ill coronavirus disease 2019 patients-a multinational observational study by the European Confederation of Medical Mycology. Clin Microbiol Infec28, 580-587. 10.1016/j.cmi.2021.08.014.
• Salmanton-Garcia, J., Honigl, M., Gangneux, J.P., Segal, E., and Cornely, O.A. (2022). Laboratory capacities to diagnose and treat invasive fungal infections in Austria, Germany and Switzerland: Results from an ECMM survey. Mycoses65, 4-4.
• Salmanton-Garcia, J., Marchesi, F., Glenthoj, A., Bilgin, Y.M., van Praet, J., Davila-Valls, J., Martin-Perez, S., Labrador, J., van Doesum, J., Falces-Romero, I., Farina, F., Schonlein, M., Chanut, M., Petzer, V., Espigado, I., Dargenio, M., Aujayeb, A., Sili, U., Serrano, L., Pinczes, L.I., de Jonge, N., Soto-Silva, A., Buquicchio, C., Prezioso, L., Marchetti, M., Meers, S., Busca, A., Corradini, P., Hoenigl, M., Koehler, P., Rahimli, L., Colak, G.M., Arellano, E., Wolf, D., Grafe, S., Ammatuna, E., Venemyr, C.B., Cornely, O.A., and Pagano, L. (2022). Improved Clinical Outcome of COVID-19 in Hematologic Malignancy Patients Receiving a Fourth Dose of Anti-SARS-CoV-2 Vaccine: An EPICOVIDEHA Report. Hemasphere6. ARTN e789. 10.1097/HS9.0000000000000789.
• Schalk, E., Seidel, D., Ruethrich, M.M., Cornely, O.A., and AGIHO, I.D.W.P. (2022). Current AGIHO Registry Studies - Results and Invitation. Oncol Res Treat45, 158-158.
• Slavin, M.A., Chen, Y.C., Cordonnier, C., Cornely, O.A., Cuenca-Estrella, M., Donnelly, J.P., Groll, A.H., Lortholary, O., Marty, F.M., Nucci, M., Rex, J.H., Rijnders, B.J.A., Thompson, G.R., Verweij, P.E., White, P.L., Hargreaves, R., Harvey, E., and Maertens, J.A. (2022). When to change treatment of acute invasive aspergillosis: an expert viewpoint. J Antimicrob Chemoth77, 16-23. 10.1093/jac/dkab317.
• Sprute, R., Grothe, J.H., Heringer, S., and Cornely, O.A. (2022). Reason and reality-identifying barriers to patient enrolment for clinical trials in invasive candidiasis. J Antimicrob Chemoth77, 3475-3481. 10.1093/jac/dkac344.
• Stemler, J., and Cornely, O.A. (2022). Antifungal Prophylaxis in Acute Myeloid Leukemia: New Drugs, New Challenges? Hemasphere6. ARTN e742. 10.1097/HS9.0000000000000742.
• Stemler, J., Kramer, T., Dimitriou, V., Wieland, U., Schumacher, S., Sprute, R., Oberste, M., Wiesmüller, G., Rau, H., Pieper, S., Bethe, U., Lehmann, C., Hellmich, M., Klein, F., Langebartels, G., and Cornely, O.A. (2022). Mobile PCR-based surveillance for SARS-CoV-2 to reduce visiting restrictions in nursing homes during the COVID-19 pandemic: a pilot study. Infection50, 607-616. 10.1007/s15010-021-01716-4.
• Stemler, J., Lackner, M., Chen, S.C.A., Hoenigl, M., and Cornely, O.A. (2022). EQUAL Score Scedosporiosis/Lomentosporiosis 2021: a European Confederation of Medical Mycology (ECMM) tool to quantify guideline adherence. J Antimicrob Chemoth77, 253-258. 10.1093/jac/dkab355.
• Stemler, J., Salmanton-Garcia, J., Weise, B., Tobben, C., Joisten, C., Fleig, J., Cornely, O.A., and Consortium, V. (2022). A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022. Infection. 10.1007/s15010-022-01931-7.
• Vogel, E., Kocher, K., Priller, A., Cheng, C.C., Steininger, P., Liao, B.H., Korber, N., Willmann, A., Irrgang, P., Held, J., Moosmann, C., Schmidt, V., Beileke, S., Wytopil, M., Heringer, S., Bauer, T., Brockhoff, R., Jeske, S., Mijocevic, H., Christa, C., Salmanton-Garcia, J., Tinnefeld, K., Bogdan, C., Yazici, S., Knolle, P., Cornely, O.A., Uberla, K., Protzer, U., Schober, K., and Tenbusch, M. (2022). Dynamics of humoral and cellular immune responses after homologous and heterologous SARS-CoV-2 vaccination with ChAdOx1 nCoV-19 and BNT162b2. Ebiomedicine85. ARTN 104294. 10.1016/j.ebiom.2022.104294.

Mauro Corrado

• Baixauli F, Piletic K, Puleston DJ, Villa M, Field CS, Flachsmann LJ, Quintana A, Rana N, Edwards-Hicks J, Matsushita M, Stanczak MA, Grzes KM, Kabat AM, Fabri M, Caputa G, Kelly B, Corrado M, Musa Y, Duda KJ, Mittler G, O’Sullivan D, Sesaki H, Jenuwein T, Buescher JM, Pearce EJ, Sanin DE, Pearce EL (2022). An LKB1–mitochondria axis controls TH17 effector function. Nature 610 (7932), 555-561. doi: 10.1038/s41586-022-05264-1. PMID: 36171294
• Corrado M, Pearce EL (2022). Targeting memory T cell metabolism to improve immunity. J Clin Invest. 2022 Jan 4;132(1):e148546. doi: 10.1172/JCI148546. PMID: 34981777; PMCID: PMC8718135.
• Corrado M, Diana M, Nicholas J(2022). Metabolites: fuelling the immune response. Clin Exp Immunol. 2022 Jun 11;208(2):129-131. doi: 10.1093/cei/uxac053. PMID: 35576509; PMCID: PMC9188342.

Claus Cursiefen

• Domdey, M., Kluth, M.A., Masslo, C., Ganss, C., Frank, M.H., Frank, N.Y., Coroneo, M.T., Cursiefen, C., and Notara, M. (2022). Consecutive dosing of UVB irradiation induces loss of ABCB5 expression and activation of EMT and fibrosis proteins in limbal epithelial cells similar to pterygium epithelium. Stem Cell Res64, 102936. 10.1016/j.scr.2022.102936.
• Volatier, T., Kluth, A., Masslo, C., Ganss, C., Frank, M.H., Frank, N., Schumacher, B., Notara, M., and Cursiefen, C.(2022). UVB activates autophagy in corneal epithelial stem cells. Invest Ophth Vis Sci63.
• Volatier, T., Schumacher, B., Cursiefen, C., and Notara, M. (2022). UV Protection in the Cornea: Failure and Rescue. Biology (Basel)11. 10.3390/biology11020278.

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Joris Deelen

• Baghdadi, M., Hinterding, H.M., Partridge, L., and Deelen, J. (2022). From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing. Briefings in Functional Genomics21, 13-23. 10.1093/bfgp/elab005.
• Cohen, A.A., Deelen, J., and Jones, O.R. (2022). Editorial: Mechanisms and Pathways Contributing to the Diversity of Aging Across the Tree of Life. Front Cell Dev Biol10, 854700. 10.3389/fcell.2022.854700.
• Timmers, P., Tiys, E.S., Sakaue, S., Akiyama, M., Kiiskinen, T.T.J., Zhou, W., Hwang, S.J., Yao, C., Biobank Japan, P., FinnGen, Deelen, J., Levy, D., Ganna, A., Kamatani, Y., Okada, Y., Joshi, P.K., Wilson, J.F., and Tsepilov, Y.A. (2022). Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging. Nat Aging2, 19-30. 10.1038/s43587-021-00159-8.

Constantinos Demetriades

• Gollwitzer, P., Grutzmacher, N., Wilhelm, S., Kummel, D., and Demetriades, C. (2022). A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids. Nat Cell Biol24, 1394-1406. 10.1038/s41556-022-00976-y.
• Huang, W., Kew, C., Fernandes, S.A., Lohrke, A., Han, L., Demetriades, C., and Antebi, A. (2022). Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity. Nat Aging2, 796-808. 10.1038/s43587-022-00275-z.
• Huang, W.M., Kew, C., Fernandes, S.D., Lohrke, A., Han, L., Demetriades, C., and Antebi, A. (2022). Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity. Nature Aging2, 796-+. 10.1038/s43587-022-00275-z.

Martin Denzel

• Allmeroth K, Hartman MD, Purrio M, Mesaros A, Denzel MS (2022). Hexosamine pathway activation improves memory but does not extend lifespan in mice. Aging Cell. 2022 Oct;21(10):e13711. doi: 10.1111/acel.13711. Epub 2022 Sep 19. PMID: 36124412; PMCID: PMC9577955.
• Kroef, V., Ruegenberg, S., Horn, M., Allmeroth, K., Ebert, L., Bozkus, S., Miethe, S., Elling, U., Schermer, B., Baumann, U., and Denzel, M.S. (2022). GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway. Elife11. ARTN e69223. 10.7554/eLife.69223.

Alexander Dilthey

• Baar, T., Dümcke, S., Gressel, S., Schwalb, B., Dilthey, A., Cramer, P., and Tresch, A. (2022). RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history. G3-Genes Genom Genet12. 10.1093/g3journal/jkac054.
• Ebler, J., Ebert, P., Clarke, W.E., Rausch, T., Audano, P.A., Houwaart, T., Mao, Y.F., Korbel, J.O., Eichler, E.E., Zody, M.C., Dilthey, A.T., and Marschall, T. (2022). Pangenome-based genome inference allows efficient and accurate genotyping across a wide spectrum of variant classes. Nature Genetics54, 518-+. 10.1038/s41588-022-01043-w.
• Houwaart, T., Belhaj, S., Tawalbeh, E., Nagels, D., Fröhlich, Y., Finzer, P., Ciruela, P., Sabrià, A., Herrero, M., Andrés, C., Antón, A., Benmoumene, A., Asskali, D., Haidar, H., von Dahlen, J., Nicolai, J., Stiller, M., Blum, J., Lange, C., Adelmann, C., Schroer, B., Osmers, U., Grice, C., Kirfel, P.P., Jomaa, H., Strelow, D., Hülse, L., Pigulla, M., Kreuzer, P., Tyshaieva, A., Weber, J., Wienemann, T., Vasconcelos, M.K., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Scholz, C.J., Jazmati, N., Göbels, K., Zotz, R., Pfeffer, K., Timm, J., Ehlkes, L., Walker, A., Dilthey, A.T., and D, G.C.-O.I. (2022). Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021. Eurosurveillance27. Artn 2101089. 10.2807/1560-7917-Es.2022.27.43.2101089.
• Walker, A., Houwaart, T., Finzer, P., Ehlkes, L., Tyshaieva, A., Damagnez, M., Strelow, D., Duplessis, A., Nicolai, J., Wienemann, T., Tamayo, T., Vasconcelos, M.K., Hulse, L., Hoffmann, K., Lubke, N., Hauka, S., Andree, M., Daumer, M.P., Thielen, A., Kolbe-Busch, S., Gobels, K., Zotz, R., Pfeffer, K., Timm, J., Dilthey, A.T., and D, G.C.-O.I. (2022). Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Clusters Based on Integrated Genomic Surveillance, Outbreak Analysis and Contact Tracing in an Urban Setting. Clin Infect Dis74, 1039-1046. 10.1093/cid/ciab588.

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Sabine Eming

• Dichtl S, Sanin DE, Koss CK, Willenborg S, Petzold A, Tanzer MC, Dahl A, Kabat AM, Lindenthal L, Zeitler L, Satzinger S, Strasser A, Mann M, Roers A, Eming SA, El Kasmi KC, Pearce EJ, Murray PJ (2022). Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF. Life Sci Alliance.2022 Jan 13;5(4):e202101315. doi: 10.26508/lsa.202101315. PMID: 35027468; PMCID: PMC8761491.
• Sanin DE, Ge Y, Marinkovic E, Kabat AM, Castoldi A, Caputa G, Grzes KM, Curtis JD, Thompson EA, Willenborg S, Dichtl S, Reinhardt S, Dahl A, Pearce EL, Eming SA, Gerbaulet A, Roers A, Murray PJ, Pearce EJ (2022). A common framework of monocyte-derived macrophage activation. Sci Immunol. 2022 Apr 15;7(70):eabl7482. doi: 10.1126/sciimmunol.abl7482. Epub 2022 Apr 15. PMID: 35427180. 
• Willenborg S, Roscito JG, Gerbaulet A, Roers A, Dahl A, Eming SA, Reinhardt S (2022). Isolation of macrophages from mouse skin wounds for single-cell RNA sequencing. STAR Protoc. 2022 Apr 19;3(2):101337. doi: 10.1016/j.xpro.2022.101337. PMID: 35496783; PMCID: PMC9046999.
• Willenborg S, Injarabian L, Eming SA (2022). Role of Macrophages in Wound Healing. Cold Spring Harb Perspect Biol. 2022 Aug 30:a041216. doi: 10.1101/cshperspect.a041216. Epub ahead of print. PMID: 36041784.
• Mikosinski, J., Kalogeropoulos, K., Bundgaard, L., Larsen, C.A., Savickas, S., Moldt Haack, A., Panczak, K., Rybolowicz, K., Grzela, T., Olszewski, M., Ciszewski, P., Sitek-Ziolkowska, K., Twardowska-Saucha, K., Karczewski, M., Rabczenko, D., Segiet, A., Buczak-Kula, P., Schoof, E.M., Eming, S.A., Smola, H., and Auf dem Keller, U. (2022). Longitudinal Evaluation of Biomarkers in Wound Fluids from Venous Leg Ulcers and Split-thickness Skin Graft Donor Site Wounds Treated with a Protease-modulating Wound Dressing. Acta Derm Venereol102, adv00834. 10.2340/actadv.v102.325.
•  Royzman, D., Peckert-Maier, K., Stich, L., Konig, C., Wild, A.B., Tauchi, M., Ostalecki, C., Kiesewetter, F., Seyferth, S., Lee, G., Eming, S.A., Fuchs, M., Kunz, M., Sturmer, E.K., Peters, E.M.J., Berking, C., Zinser, E., and Steinkasserer, A. (2022). Soluble CD83 improves and accelerates wound healing by the induction of pro-resolving macrophages. Front Immunol13, 1012647. 10.3389/fimmu.2022.1012647.
• Wang, J., Eming, S.A., and Ding, X. (2022). Role of mTOR Signaling Cascade in Epidermal Morphogenesis and Skin Barrier Formation. Biology (Basel)11. 10.3390/biology11060931 .

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Lukas P. Frenzel

• Izquierdo E, Vorholt D, Blakemore SJ, Sackey B, Nolte JL, Barbarino V, Schmitz JH, Nickel N, Bachurski D, Lobastova L, Nikolic M, Michalik M, Brinker R, Merkel O, Franitza M, Georgomanolis T, Neuhaus R, Koch MRK, Nasada N, Knittel G, Chapuy B, Ludwig N, Meese E, Frenzel LP, Reinhardt HC, Peifer M, Rebollido-Rios R, Bruns H, Krüger M, Hallek M, Pallasch CP (2022).Extracellular vesicles and PDL1 suppress macrophages inducing therapy resistance in TP53-deficient B-cell malignancies. Blood. 2022 Mar 28:blood.2021014007. doi: 10.1182/blood.2021014007. Epub ahead of print. PMID: 35344582.
• Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling CD, Nieper P, Feldmann T, Merkel O, Lorsy E, da Palma Guerreiro A, von Jan J, Kisis I, Wasserburger E, Claasen J, Faitschuk-Meyer E, Altmüller J, Nürnberg P, Yang TP, Lienhard M, Herwig R, Kreuzer KA, Pallasch CP, Buettner R, Schäfer SC, Hartley J, Abken H, Peifer M, Kashkar H, Knittel G, Eichhorst B, Ullrich RT, Herling M, Reinhardt HC, Hallek M, Schweiger MR, Frenzel LP (2022). Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies. Blood. 2022 Jun 15:blood.2021014304. doi: 10.1182/blood.2021014304. Epub ahead of print. PMID: 35704690.
• Flores-Romero, H., Hohorst, L., John, M., Albert, M.C., King, L.E., Beckmann, L., Szabo, T., Hertlein, V., Luo, X., Villunger, A., Frenzel, L.P., Kashkar, H., and Garcia-Saez, A.J. (2022). BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. Embo J41. ARTN e108690. 10.15252/embj.2021108690.
• Ryan, D.G., and Frezza, C. (2022). Metabolic symbiosis in pancreatic cancer. Nat Cancer3, 1277-1278. 10.1038/s43018-022-00454-2.
• Sciacovelli, M., Dugourd, A., Jimenez, L.V., Yang, M., Nikitopoulou, E., Costa, A.S.H., Tronci, L., Caraffini, V., Rodrigues, P., Schmidt, C., Ryan, D.G., Young, T., Zecchini, V.R., Rossi, S.H., Massie, C., Lohoff, C., Masid, M., Hatzimanikatis, V., Kuppe, C., Von Kriegsheim, A., Kramann, R., Gnanapragasam, V., Warren, A.Y., Stewart, G.D., Erez, A., Vanharanta, S., Saez-Rodriguez, J., and Frezza, C. (2022). Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression. Nat Commun13, 7830. 10.1038/s41467-022-35036-4.

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Christian Frezza

• Pouikli A, Maleszewska M, Parekh S, Yang M, Nikopoulou C, Bonfiglio JJ, Mylonas C, Sandoval T, Schumacher AL, Hinze Y, Matic I, Frezza C, Tessarz P (2022). Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial nuclear communication. EMBO J. 2022 Oct 24:e111239. doi:10.15252/embj.2022111239. Epub ahead of print. PMID: 36278281. 
• Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, Harle V, Offord V, Wong K, Mora A, Speed A, Caraffini V, Tran MGB, Maher ER, Stewart GD, Vanharanta S, Adams DJ, Frezza C (2022). HIRA loss transforms FH-deficient cells. Sci Adv. 2022 Oct 21;8(42):eabq8297. doi:10.1126/sciadv.abq8297. Epub 2022 Oct 21. PMID: 36269833; PMCID: PMC9586478. 
• Allen FM, Costa ASH, Gruszczyk AV, Bates GR, Prag HA, Nikitopoulou E, Viscomi C, Frezza C, James AM, Murphy MP (2022). Rapid fractionation of mitochondria from mouse liver and heart reveals in vivo metabolite compartmentation. FEBS Lett. 2022 Oct 11. doi: 10.1002/1873-3468.14511. Epub ahead of print. PMID: 36217875. 
• Lundahl MLE, Mitermite M, Ryan DG, Case S, Williams NC, Yang M, Lynch RI, Lagan E, Lebre FM, Gorman AL, Stojkovic B, Bracken AP, Frezza C, Sheedy FJ, Scanlan EM, O'Neill LAJ, Gordon SV, Lavelle EC (2022). Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses. Elife. 2022 Sep 29;11:e74690. doi: 10.7554/eLife.74690. PMID: 36173104; PMCID: PMC9555863. 
• Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido GA 2nd, Gorman JH 3rd, Gorman RC, Rabinowitz JD (2022). Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metab. 2022 Sep 6;34(9):1410. doi:10.1016/j.cmet.2022.08.006. Erratum for: Cell Metab. 2019 Sep 3;30(3):594-606.e3. PMID: 36070684; PMCID: PMC9514224. 
• Harris R, Yang M, Schmidt C, Royet C, Singh S, Natarajan A, Morris M, Frezza C, Laman H (2022). Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells. J Cell Biol. 2022 Jul 4;221(7):e202203095. doi: 10.1083/jcb.202203095. Epub 2022 Jun 7. PMID: 35670764; PMCID: PMC9178409. 
• Riedel A, Helal M, Pedro L, Swietlik JJ, Shorthouse D, Schmitz W, Haas L, Young T, da Costa ASH, Davidson S, Bhandare P, Wolf E, Hall BA, Frezza C, Oskarsson T, Shields JD (2022). Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma. Cancer Immunol Res. 2022 Apr 1;10(4):482-497. doi: 10.1158/2326-6066.CIR-21-0778. PMID: 35362044; PMCID: PMC7612582. 
• Srinivas US, Tay NSC, Jaynes P, Anbuselvan A, Ramachandran GK, Wardyn JD, Hoppe MM, Hoang PM, Peng Y, Lim S, Lee MY, Peethala PC, An O, Shendre A, Tan BWQ, Jemimah S, Lakshmanan M, Hu L, Jakhar R, Sachaphibulkij K, Lim LHK, Pervaiz S, Crasta K, Yang H, Tan P, Liang C, Ho L, Khanchandani V, Kappei D, Yong WP, Tan DSP, Bordi M, Campello S, Tam WL, Frezza C, Jeyasekharan AD (2022). PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production. Oncogene. 2022 Mar;41(13):1986-2002. doi: 10.1038/s41388-022-02219-8. Epub 2022 Mar 2. Erratum in: Oncogene. 2022 Jun;41(24):3382. PMID: 35236967. 
• Sarlak S, Lalou C, Sant'Anna-Silva ACB, Mafhouf W, De Luise M, Rousseau B, Izotte J, Claverol S, Lacombe D, Nikitopoulou E, Yang M, Oliveira M, Frezza C, Gasparre G, Rezvani HR, Amoedo ND, Rossignol R (2022). Lung Tumor Growth Promotion by Tobacco-Specific Nitrosamines Involves the β2-Adrenergic Receptors-Dependent Stimulation of Mitochondrial REDOX Signaling. Antioxid Redox Signal. 2022 Mar;36(7-9):525-549. doi: 10.1089/ars.2020.8259. PMID: 34715750. 
• Ryan DG, Knatko EV, Casey AM, Hukelmann JL, Dayalan Naidu S, Brenes AJ, Ekkunagul T, Baker C, Higgins M, Tronci L, Nikitopolou E, Honda T, Hartley RC, O'Neill LAJ, Frezza C, Lamond AI, Abramov AY, Arthur JSC, Cantrell DA, Murphy MP, Dinkova-Kostova AT (2022). Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response. iScience. 2022 Jan 30;25(2):103827. doi: 10.1016/j.isci.2022.103827. PMID: 35198887; PMCID: PMC8844662. 
• Petruzzelli M, Ferrer M, Schuijs MJ, Kleeman SO, Mourikis N, Hall Z, Perera D, Raghunathan S, Vacca M, Gaude E, Lukey MJ, Jodrell DI, Frezza C, Wagner EF, Venkitaraman AR, Halim TYF, Janowitz T (2022). Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia. Cancers(Basel). 2022 Feb 15;14(4):963. doi: 10.3390/cancers14040963. PMID: 35205709; PMCID: PMC8870098. 
• Williams NC, Ryan DG, Costa ASH, Mills EL, Jedrychowski MP, Cloonan SM, Frezza C, O'Neill LA (2022). Signaling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages. J Biol Chem. 2022 Feb;298(2):101501. doi: 10.1016/j.jbc.2021.101501. Epub 2021 Dec 17. PMID: 34929172; PMCID: PMC8784330.

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Henning Fenselau

• Steuernagel L, Lam BYH, Klemm P, Dowsett GKC, Bauder CA, Tadross JA, Hitschfeld TS, Del Rio Martin A, Chen W, de Solis AJ, Fenselau H, Davidsen P, Cimino I, Kohnke SN, Rimmington D, Coll AP, Beyer A, Yeo GSH, Brüning JC (2022). HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus. NatMetab. 2022 Oct;4(10):1402-1419.

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Ana J. García-Sáez

• Jenner A, Peña-Blanco A, Salvador-Gallego R, Ugarte-Uribe B, Zollo C, Ganief T, Bierlmeier J, Mund M, Lee JE, Ries J, Schwarzer D, Macek B, Garcia-Saez AJ (2022). DRP1 interacts directly with BAX to induce its activation and apoptosis. EMBO J. 2022 Apr 19:41(8):e108587. doi: 10.15252/embj.2021108587. Epub ahead of print. PMID: 35023587. 
• Danial JSH, Quintana Y, Ros U, Shalaby R, Margheritis EG, Chumpen Ramirez S, Ungermann C, Garcia-Saez AJ, Cosentino K (2022). Systematic Assessment of the Accuracy of Subunit Counting in Biomolecular Complexes Using Automated Single-Molecule Brightness Analysis. J Phys Chem Lett. 2022 Jan 27;13(3):822-829. doi: 10.1021/acs.jpclett.1c03835. Epub 2022 Jan 19. PMID: 35044771; PMCID: PMC8802318.
• Cosentino K, Hertlein V, Jenner A, Dellmann T, Gojkovic M, Peña-Blanco A, Dadsena S, Wajngarten N, Danial JSH, Thevathasan JV, Mund M, Ries J, Garcia-Saez AJ (2022). The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation. Mol Cell. 2022 Mar 3;82(5):933-949.e9. doi: 10.1016/j.molcel.2022.01.008. Epub 2022 Feb 3. PMID: 35120587; PMCID: PMC8901441.
• Guéguinou M, Ibrahim S, Bourgeais J, Robert A, Pathak T, Zhang X, Crottès D, Dupuy J, Ternant D, Monbet V, Guibon R, Flores-Romero H, Lefèvre A, Lerondel S, Le Pape A, Dumas JF, Frank PG, Girault A, Chautard R, Guéraud F, García-Sáez AJ, Ouaissi M, Emond P, Sire O, Hérault O, Fromont-Hankard G, Vandier C, Tougeron D, Trebak M, Raoul W, Lecomte T (2022). Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer. Cell Mol Life Sci. 2022 May 8;79(6):284. doi: 10.1007/s00018-022-04311-4. PMID: 35526196.
• Flores-Romero H, García-Sáez AJ. MERLIN: A BRET-Based Proximity Biosensor for Studying Mitochondria-ER Contact Sites. Methods Mol Biol. 2022;2525:197-205. doi: 10.1007/978-1-0716-2473-9_14. PMID: 35836069.
• Flores-Romero H, Hohorst L, John M, Albert MC, King LE, Beckmann L, Szabo T, Hertlein V, Luo X, Villunger A, Frenzel LP, Kashkar H, Garcia-Saez AJ (2022). BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. EMBO J. Dec 17;41(2):e108690. doi: 10.15252/embj.2021108690
• Shalaby R, Diwan A, Flores-Romero H, Hertlein V, Garcia-Saez AJ (2022). Visualization of BOK pores independent of BAX and BAK reveals a similar mechanism with differing regulation. Cell Death Differ. 2022 Oct 26:1-11. doi: 10.1038/s41418-022-01078-w. Online ahead of print. PMID: 36289446

Martin Graef

• Grossbach, J., Gillet, L., Clement-Ziza, M., Schmalohr, C.L., Schubert, O.T., Schutter, M., Mawer, J.S.P., Barnes, C.A., Bludau, I., Weith, M., Tessarz, P., Graef, M., Aebersold, R., and Beyer, A. (2022). The impact of genomic variation on protein phosphorylation states and regulatory networks. Mol Syst Biol18. ARTN e10712. 10.15252/msb.202110712.

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Robert Hänsel-Hertsch

• Hudecova I, Smith CG, Hänsel-Hertsch R, Chilamakuri CS, Morris JA, Vijayaraghavan A, Heider K, Chandrananda D, Cooper WN, Gale D, Garcia-Corbacho J, Pacey S, Baird RD, Rosenfeld N, Mouliere F (2022). Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA. Genome Res. 2022 Feb;32(2):215-227. doi: 10.1101/gr.275691.121. Epub 2021 Dec 20. PMID: 34930798; PMCID: PMC8805718.

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Michael Hallek

• Baumann, F.T., Reimer, N., Gockeln, T., Reike, A., Hallek, M., Ricci, C., Zopf, E.M., Schmid, D., Taaffe, D., Newton, R.U., Galvao, D.A., and Leitzmann, M. (2022). Supervised pelvic floor muscle exercise is more effective than unsupervised pelvic floor muscle exercise at improving urinary incontinence in prostate cancer patients following radical prostatectomy - a systematic review and meta-analysis. Disabil Rehabil44, 5374-5385. 10.1080/09638288.2021.1937717.
• Bonifacius, A., Tischer-Zimmermann, S., Santamorena, M.M., Mausberg, P., Schenk, J., Koch, S., Barnstorf-Brandes, J., Godecke, N., Martens, J., Goudeva, L., Verboom, M., Wittig, J., Maecker-Kolhoff, B., Baurmann, H., Clark, C., Brauns, O., Simon, M., Lang, P., Cornely, O.A., Hallek, M., Blasczyk, R., Seiferling, D., Kohler, P., and Eiz-Vesper, B. (2022). Rapid Manufacturing of Highly Cytotoxic Clinical-Grade SARS-CoV-2-specific T Cell Products Covering SARS-CoV-2 and Its Variants for Adoptive T Cell Therapy. Front Bioeng Biotech10. ARTN 867042. 10.3389/fbioe.2022.867042.
• Borchmann, S., Selenz, C., Lohmann, M., Ludwig, H., Gassa, A., Bragelmann, J., Lohneis, P., Meder, L., Mattlener, J., Breid, S., Nill, M., Fassunke, J., Wisdom, A.J., Compes, A., Gathof, B., Alakus, H., Kirsch, D., Hekmat, K., Buttner, R., Reinhardt, H.C., Hallek, M., and Ullrich, R.T. (2022). Tripartite antigen-agnostic combination immunotherapy cures established poorly immunogenic tumors. J Immunother Cancer10. 10.1136/jitc-2022-004781.
• Borrega, J.G., Heger, J.M., Koehler, P., Holtick, U., Hallek, M., Scheid, C., Böll, B., Shimabukuro-Vornhagen, A., Kochanek, M., and Eichenauer, D.A. (2022). Allogeneic stem cell transplant recipients admitted to the intensive care unit during the peri-transplant period have unfavorable outcomes-results of a retrospective analysis from a German university hospital. Ann Hematol101, 389-395. 10.1007/s00277-021-04698-3.
• Castelli, L., Elter, T., Wolf, F., Watson, M., Schenk, A., Steindorf, K., Bloch, W., Hallek, M., Joisten, N., and Zimmer, P. (2022). Sleep problems and their interaction with physical activity and fatigue in hematological cancer patients during onset of high dose chemotherapy. Support Care Cancer30, 167-176. 10.1007/s00520-021-06377-5.
• Cramer, P., Furstenau, M., Robrecht, S., Giza, A., Zhang, C., Fink, A.M., Fischer, K., Langerbeins, P., Al-Sawaf, O., Tausch, E., Schneider, C., Schetelig, J., Dreger, P., Bottcher, S., Kreuzer, K.A., Schilhabel, A., Ritgen, M., Bruggemann, M., Kneba, M., Stilgenbauer, S., Eichhorst, B., and Hallek, M. (2022). Obinutuzumab, acalabrutinib, and venetoclax, after an optional debulking with bendamustine in relapsed or refractory chronic lymphocytic leukaemia (CLL2-BAAG): a multicentre, open-label, phase 2 trial. Lancet Haematol9, e745-e755. 10.1016/S2352-3026(22)00211-3.
• de Oliveira, T.D., Vom Stein, A., Rebollido-Rios, R., Lobastova, L., Lettau, M., Janssen, O., Wagle, P., Nguyen, P.H., Hallek, M., and Hansen, H.P. (2022). Stromal cells support the survival of human primary chronic lymphocytic leukemia (CLL) cells through Lyn-driven extracellular vesicles. Front Med (Lausanne)9, 1059028. 10.3389/fmed.2022.1059028.
• Furstenau, M., Weiss, J., Giza, A., Franzen, F., Robrecht, S., Fink, A.M., Fischer, K., Schneider, C., Tausch, E., Stilgenbauer, S., Ritgen, M., Schilhabel, A., Bruggemann, M., Eichhorst, B., Hallek, M., and Cramer, P. (2022). Circulating Tumor DNA-Based MRD Assessment in Patients with CLL Treated with Obinutuzumab, Acalabrutinib, and Venetoclax. Clin Cancer Res28, 4203-4211. 10.1158/1078-0432.CCR-22-0433.
• Gehlsen, U., Stern, M.E., Franklin, J., Tahmaz, V., Hallek, M., Holtick, U., Scheid, C., and Steven, P. (2022). Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease. Transplant Cell Ther28, 782 e781-782 e787. 10.1016/j.jtct.2022.07.027.
• Hallek, M., Ockenfels, A., and Wiesen, D. (2022). Behavioral Economics Interventions to Improve Medical Decision-Making. Dtsch Arztebl Int119, 633-639. 10.3238/arztebl.m2022.0275.
• Hieber, M.L., Sprute, R., Eichenauer, D.A., Hallek, M., and Jachimowicz, R.D. (2022). Hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination. Infection50, 1399-1404. 10.1007/s15010-022-01786-y.
• Izquierdo, E., Vorholt, D., Blakemore, S., Sackey, B., Nolte, J.L., Barbarino, V., Schmitz, J., Nickel, N., Bachurski, D., Lobastova, L., Nikolic, M., Michalik, M., Brinker, R., Merkel, O., Franitza, M., Georgomanolis, T., Neuhaus, R., Koch, M., Nasada, N., Knittel, G., Chapuy, B., Ludwig, N., Meese, E., Frenzel, L., Reinhardt, H.C., Peifer, M., Rebollido-Rios, R., Bruns, H., Kruger, M., Hallek, M., and Pallasch, C.P. (2022). Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53-deficient B-cell malignancies. Blood139, 3617-3629. 10.1182/blood.2021014007.
• Knisbacher, B.A., Lin, Z., Hahn, C.K., Nadeu, F., Duran-Ferrer, M., Stevenson, K.E., Tausch, E., Delgado, J., Barbera-Mourelle, A., Taylor-Weiner, A., Bousquets-Munoz, P., Diaz-Navarro, A., Dunford, A., Anand, S., Kretzmer, H., Gutierrez-Abril, J., Lopez-Tamargo, S., Fernandes, S.M., Sun, C., Sivina, M., Rassenti, L.Z., Schneider, C., Li, S., Parida, L., Meissner, A., Aguet, F., Burger, J.A., Wiestner, A., Kipps, T.J., Brown, J.R., Hallek, M., Stewart, C., Neuberg, D.S., Martin-Subero, J.I., Puente, X.S., Stilgenbauer, S., Wu, C.J., Campo, E., and Getz, G. (2022). Molecular map of chronic lymphocytic leukemia and its impact on outcome. Nat Genet54, 1664-1674. 10.1038/s41588-022-01140-w.
• Kusch, M., Labouvie, H., Schiewer, V., Talalaev, N., Cwik, J.C., Bussmann, S., Vaganian, L., Gerlach, A.L., Dresen, A., Cecon, N., Salm, S., Krieger, T., Pfaff, H., Lemmen, C., Derendorf, L., Stock, S., Samel, C., Hagemeier, A., Hellmich, M., Leicher, B., Hultenschmidt, G., Swoboda, J., Haas, P., Arning, A., Gottel, A., Schwickerath, K., Graeven, U., Houwaart, S., Kerek-Bodden, H., Krebs, S., Muth, C., Hecker, C., Reiser, M., Mauch, C., Benner, J., Schmidt, G., Karlowsky, C., Vimalanandan, G., Matyschik, L., Galonska, L., Francke, A., Osborne, K., Nestle, U., Baumer, M., Schmitz, K., Wolf, J., and Hallek, M. (2022). Integrated, cross-sectoral psycho-oncology (isPO): a new form of care for newly diagnosed cancer patients in Germany. BMC Health Serv Res22, 543. 10.1186/s12913-022-07782-0.
• Kutsch, N., Godel, P., Voltin, C.A., Kobe, C., Hallek, M., Scheid, C., Borchmann, P., and Holtick, U. (2022). Sustained Remission of Relapsed Diffuse Large B-cell Lymphoma After Safe Administration of CD19-directed CAR T-cells in a Patient With Chronic Intestinal and Pulmonal GvHD. Hemasphere6, e735. 10.1097/HS9.0000000000000735.
• Kutsch, N., Pallasch, C., Decker, T., Hebart, H., Chow, K.U., Graeven, U., Kisro, J., Kroeber, A., Tausch, E., Fischer, K., Fink, A.M., Wendtner, C.M., Ritgen, M., Stilgenbauer, S., Zhang, D., Li, B., Jurgensmeier, J.M., Rajakumaraswamy, N., Bhargava, P., Hallek, M., and Eichhorst, B. (2022). Efficacy and Safety of Tirabrutinib and Idelalisib With or Without Obinutuzumab in Relapsed Chronic Lymphocytic Leukemia. Hemasphere6, e729. 10.1097/HS9.0000000000000729.
• Langerbeins, P., and Hallek, M. (2022). COVID-19 in patients with hematologic malignancy. Blood140, 236-252. 10.1182/blood.2021012251.
• Mellinghoff, S.C., Mayer, L., Robrecht, S., Weskamm, L.M., Dahlke, C., Gruell, H., Schlotz, M., Vanshylla, K., Schloser, H.A., Thelen, M., Fink, A.M., Fischer, K., Klein, F., Addo, M.M., Eichhorst, B., Hallek, M., and Langerbeins, P. (2022). SARS-CoV-2-specific cellular response following third COVID-19 vaccination in patients with chronic lymphocytic leukemia. Haematologica107, 2480-2484. 10.3324/haematol.2022.280982.
• Rusyn, L., Reinartz, S., Nikiforov, A., Mikhael, N., Vom Stein, A., Kohlhas, V., Bloehdorn, J., Stilgenbauer, S., Lohneis, P., Buettner, R., Robrecht, S., Fischer, K., Pallasch, C., Hallek, M., Nguyen, P.H., and Seeger-Nukpezah, T. (2022). The scaffold protein NEDD9 is necessary for leukemia-cell migration and disease progression in a mouse model of chronic lymphocytic leukemia. Leukemia36, 1794-1805. 10.1038/s41375-022-01586-1.
• Samineni, D., Gibiansky, L., Wang, B., Vadhavkar, S., Rajwanshi, R., Tandon, M., Sinha, A., Al-Sawaf, O., Fischer, K., Hallek, M., Salem, A.H., Li, C., and Miles, D. (2022). Pharmacokinetics and Exposure-Response Analysis of Venetoclax + Obinutuzumab in Chronic Lymphocytic Leukemia: Phase 1b Study and Phase 3 CLL14 Trial. Adv Ther39, 3635-3653. 10.1007/s12325-022-02170-w.
• Schilhabel, A., Walter, P.J., Cramer, P., von Tresckow, J., Kohlscheen, S., Szczepanowski, M., Laqua, A., Fischer, K., Eichhorst, B., Bottcher, S., Schneider, C., Tausch, E., Bruggemann, M., Kneba, M., Hallek, M., and Ritgen, M. (2022). CD20 Expression as a Possible Novel Prognostic Marker in CLL: Application of EuroFlow Standardization Technique and Normalization Procedures in Flow Cytometric Expression Analysis. Cancers (Basel)14. 10.3390/cancers14194917.
• Sharman, J.P., Biondo, J.M.L., Boyer, M., Fischer, K., Hallek, M., Jiang, D., Kater, A.P., Porro Lura, M., and Wierda, W.G. (2022). A review of the incidence of tumor lysis syndrome in patients with chronic lymphocytic leukemia treated with venetoclax and debulking strategies. EJHaem3, 492-506. 10.1002/jha2.427.
• Simon, F., Giza, A., Robrecht, S., Fink, A.M., Cramer, P., von Tresckow, J., Furstenau, M., Goede, V., Tausch, E., Schneider, C., Stilgenbauer, S., Wendtner, C.M., Eichhorst, B., Fischer, K., Hallek, M., and Al-Sawaf, O. (2022). Pooled analysis of first-line treatment with targeted agents in patients with chronic lymphocytic leukemia aged 80 years and older. Leuk Lymphoma63, 3299-3306. 10.1080/10428194.2022.2123223.
• Theobald, S.J., Simonis, A., Mudler, J.M., Gobel, U., Acton, R., Kohlhas, V., Albert, M.C., Hellmann, A.M., Malin, J.J., Winter, S., Hallek, M., Walczak, H., Nguyen, P.H., Koch, M., and Rybniker, J. (2022). Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS-CoV-2 mRNA vaccination. EMBO Mol Med14, e15888. 10.15252/emmm.202215888.
• Thomalla, D., Beckmann, L., Grimm, C., Oliverio, M., Meder, L., Herling, C.D., Nieper, P., Feldmann, T., Merkel, O., Lorsy, E., da Palma Guerreiro, A., von Jan, J., Kisis, I., Wasserburger, E., Claasen, J., Faitschuk-Meyer, E., Altmuller, J., Nurnberg, P., Yang, T.P., Lienhard, M., Herwig, R., Kreuzer, K.A., Pallasch, C.P., Buttner, R., Schafer, S.C., Hartley, J., Abken, H., Peifer, M., Kashkar, H., Knittel, G., Eichhorst, B., Ullrich, R.T., Herling, M., Reinhardt, H.C., Hallek, M., Schweiger, M.R., and Frenzel, L.P. (2022). Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies. Blood140, 2113-2126. 10.1182/blood.2021014304.
• von Tresckow, J., Cramer, P., Robrecht, S., Langerbeins, P., Fink, A.M., Al-Sawaf, O., Furstenau, M., Illmer, T., Klaproth, H., Tausch, E., Ritgen, M., Fischer, K., Wendtner, C.M., Kreuzer, K.A., Stilgenbauer, S., Bottcher, S., Eichhorst, B.F., and Hallek, M. (2022). Sequential treatment with bendamustine, obinutuzumab (GA101) and Ibrutinib in chronic lymphocytic leukemia (CLL): final results of the CLL2-BIG trial. Leukemia36, 2125-2128. 10.1038/s41375-022-01629-7.

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Jan Hoeijmakers

• Oudmaijer CAJ, Minnee RC, Pol RA, van den Boogaard WMC, Komninos DSJ, van de Wetering J, van Heugten MH, Hoorn EJ, Sanders JSF, Hoeijmakers JHJ, Vermeij WP, IJzermans JNM (2022). Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trial. Trials. 2022 Jan 6;23(1):18. doi: 10.1186/s13063-021-05950-x. PMID: 34991694; PMCID: PMC8733810.
• Vougioukalaki M, Demmers J, Vermeij WP, Baar M, Bruens S, Magaraki A, Kuijk E, Jager M, Merzouk S, Brandt RMC, Kouwenberg J, van Boxtel R, Cuppen E, Pothof J, Hoeijmakers JHJ (2022). Different responses to DNA damage determine ageing differences between organs. Aging Cell. 2022 Apr;21(4):e13562. doi: 10.1111/acel.13562. Epub 2022 Mar 4. PMID: 35246937; PMCID: PMC9009128.
• Kajitani GS, Quayle C, Garcia CCM, Fotoran WL, Dos Santos JFR, van der Horst GTJ,Hoeijmakers JHJ, Menck CFM (2022).Photorepair of Either CPD or 6-4PP DNA Lesions in Basal Keratinocytes Attenuates Ultraviolet-Induced Skin Effects in Nucleotide Excision Repair Deficient Mice. Front Immunol. 2022 Mar 29;13:800606. doi: 10.3389/fimmu.2022.800606. PMID: 35422806; PMCID: PMC9004445.
• He Y, van Mever M, Yang W, Huang L, Ramautar R, Rijksen Y, Vermeij WP, Hoeijmakers JHJ, Harms AC, Lindenburg PW, Hankemeier T (2022). A Sample Preparation Method for the Simultaneous Profiling of Signaling Lipids and Polar Metabolites in Small Quantities of Muscle Tissues from a Mouse Model for Sarcopenia. Metabolites. Aug 12;12(8):742. doi: 10.3390/metabo12080742. PMID: 36005613; PMCID: PMC9413361.
• Birkisdóttir MB, van Galen I, Brandt RMC, Barnhoorn S, van Vliet N, van Dijk C, Nagarajah B, Imholz S, van Oostrom CT, Reiling E, Gyenis Á, Mastroberardino PG, Jaarsma D, van Steeg H, Hoeijmakers JHJ, Dollé MET, Vermeij WP. The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside. Front Aging. 2022 Oct 12;3:1005322. doi: 10.3389/fragi.2022.1005322. eCollection 2022.PMID: 3631318
• Oudmaijer CAJ, Berk KA, van der Louw EJTM, de Man R, van der Lelij AJ, Hoeijmakers JHJ, IJzermans J. KETOgenic diet therapy in patients with HEPatocellular adenoma: study protocol of a matched interventional cohort study. BMJ Open. 2022 Feb 15;12(2):e053559. doi: 10.1136/bmjopen-2021-053559.PMID: 35168973
• Oudmaijer CAJ, van den Boogaard WMC, Komninos DSJ, Verwaaijen EJ, van Santen HM, Lilien MR, Hoeijmakers JHJ, Wijnen MHW, van den Heuvel-Eibrink MM, Vermeij WP. Fasting Intervention for Children With Unilateral Renal Tumors to Reduce Toxicity. Front Pediatr. 2022 Jan 27;10:828615. doi: 10.3389/fped.2022.828615. eCollection 2022.PMID: 35155309
• Birkisdottir, M.B., Van't Sant, L.J., Brandt, R.M.C., Barnhoorn, S., Hoeijmakers, J.H.J., Vermeij, W.P., and Jaarsma, D. (2022). Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health. Front Aging Neurosci14, 1095801. 10.3389/fnagi.2022.1095801.

Thorsten Hoppe    

• Segref A., Vakkayil K.L., Padvitski T., Li Q., Kroef V., Lormann J., Körner L., Finger F., Hoppe T (2022). Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling. Nat Commun. 13, 5874.
• Ravanelli S., Li Q., Annibal A., Trifunovic A., Antebi A., Hoppe T (2022). Reprograming of proteaso-mal degradation by branched chain amino acid metabolism. Aging Cell: e13725.
• Balaji V., Müller L., Lorenz R., Kevei E., Zhang W.H., Santiago U., Gebauer J., Llamas E., Vilchez E., Camacho C.J., Pokrzywa W., Hoppe T (2022). A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing. Mol Cell. 82, 3239-54.
• Das A., Thapa P., Santiago U., Shanmugam N., Banasiak K., Dabrowska K., Nolte H., Szulc N.A., Gathungu R.M., Cysewski D., Krüger M., Dadlez M., Nowotny M., Camacho C.J., Hoppe T., Pokrzywa W (2022). A heterotypic assembly mechanism regulates CHIP E3 ligase activity. EMBO J. 41: e109566.
• Vakkayil K.L. and Hoppe T. (2022). Temperature-Dependent Regulation of Proteostasis and Longevity. Front. Aging 3: 853588.
• Efstathiou, S., Ottens, F., Schutter, L.S., Ravanelli, S., Charmpilas, N., Gutschmidt, A., Le Pen, J., Gehring, N.H., Miska, E.A., Boucas, J., and Hoppe, T. (2022). ER-associated RNA silencing promotes ER quality control. Nat Cell Biol24, 1714-1725. 10.1038/s41556-022-01025-4.
• Hermeling, J.C., Herholz, M., Baumann, L., Cores, E.C., Zecic, A., Hoppe, T., Riemer, J., and Trifunovic, A. (2022). Mitochondria-originated redox signalling regulates KLF-1 to promote longevity in Caenorhabditis elegans. Redox Biol58, 102533. 10.1016/j.redox.2022.102533.
• Ottens, F., Franz, A., and Hoppe, T. (2022). Correction to: Build-UPS and break-downs: metabolism impacts on proteostasis and aging. Cell Death Differ29, 465. 10.1038/s41418-021-00800-4.

Tamas Horvath

• Endle, H., Horta, G., Stutz, B., Muthuraman, M., Tegeder, I., Schreiber, Y., Snodgrass, I.F., Gurke, R., Liu, Z.W., Sestan-Pesa, M., Radyushkin, K., Streu, N., Fan, W., Baumgart, J., Li, Y., Kloss, F., Groppa, S., Opel, N., Dannlowski, U., Grabe, H.J., Zipp, F., Racz, B., Horvath, T.L., Nitsch, R., and Vogt, J. (2022). AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids. Nat Metab4, 683-692. 10.1038/s42255-022-00589-7.
• Ralevski A, Apelt F, Olas JJ, Mueller-Roeber B, Rugarli EI, Kragler F, Horvath TL (2022). Plant mitochondrial FMT and its mammalian homolog CLUH controls development and behavior in Arabidopsis and locomotion in mice. Cell Mol Life Sci. 2022 Jun 2;79(6):334. doi: 10.1007/s00018-022-04382-3. PMID: 35652974.

Pitter Huesgen

• Willems P, Huesgen PF, Finkemeier I, Graciet E, Meinnel T and Van Breusegem F (2022) Editorial: Plant protein termini: Their generation, modification and function. Front. Plant Sci. 13:1040392. doi: 10.3389/fpls.2022.1040392
• Oberleitner L, Perrar A, Macorano L, Huesgen PF, Nowack ECM (2022). A bipartite chromatophore transit peptide and N-terminal protein processing in the Paulinella chromatophore. Plant Physiol. 2022 Jan 19:kiac012. doi: 10.1093/plphys/kiac012. Epub ahead of print. PMID: 35043947. 
• Huebbers JW, Büttgen K, Leissing F, Mantz M, Pauly M, Huesgen PF, Panstruga R (2022). An advanced method for the release, enrichment and purification of high-quality Arabidopsis thaliana rosette leaf trichomes enables profound insights into the trichome proteome. Plant Methods. 2022 Jan 28;18(1):12. doi: 10.1186/s13007-021-00836-0. PMID: 35086542; PMCID: PMC8796501. 
• Demir F, Huesgen PF (2022). A User Guide to Validation, Annotation, and Evaluation of N-Terminome Datasets with MANTI. Methods Mol Biol. 2022;2447:271-283. doi: 10.1007/978-1-0716-2079-3_22. PMID: 35583789.
• Demir F, Kuppusamy M, Perrar A, Huesgen PF (2022). Profiling Sequence Specificity of Proteolytic Activities Using Proteome-Derived Peptide Libraries. Methods Mol Biol. 2022;2447:159-174. doi: 10.1007/978-1-0716-2079-3_13. PMID: 35583780.
• Demir F, Perrar A, Mantz M, Huesgen PF (2022). Sensitive Plant N-Terminome Profiling with HUNTER. Methods Mol Biol. 2022;2447:139-158. doi: 10.1007/978-1-0716-2079-3_12. PMID: 35583779.
• Kuppusamy M, Huesgen PF* (2022) “Omics” approaches to determine protease degradomes in complex biological matrices. Proteolytic Signaling in Health and Disease, 209-228.

Ina Huppertz

• Buscher, M., Horos, R., Huppertz, I., Haubrich, K., Dobrev, N., Baudin, F., Hennig, J., and Hentze, M.W. (2022). Vault RNA1-1 riboregulates the autophagic function of p62 by binding to lysine 7 and arginine 21, both of which are critical for p62 oligomerization. RNA28, 742-755. 10.1261/rna.079129.122.
• Huppertz, I., Perez-Perri, J.I., Mantas, P., Sekaran, T., Schwarzl, T., Russo, F., Ferring-Appel, D., Koskova, Z., Dimitrova-Paternoga, L., Kafkia, E., Hennig, J., Neveu, P.A., Patil, K., and Hentze, M.W. (2022). Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation. Mol Cell82, 2666-2680 e2611. 10.1016/j.molcel.2022.05.019.

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Sandra Iden

• Baess, S.C., Burkhart, A.K., Cappello, S., Graband, A., Seré, K., Zenke, M., Niemann, C., and Iden, S. (2022). Lrig1-and Wnt-dependent niches dictate segregation of resident immune cells and melanocytes in murine tail epidermis. Development149. ARTN dev200154. 10.1242/dev.200154.
• Koehler, S., Odenthal, J., Ludwig, V., Jess, D.U., Höhne, M., Jüngst, C., Grawe, F., Helmstädter, M., Janku, J.L., Bergmann, C., Hoyer, P.F., Hagmann, H.H., Walz, G., Bloch, W., Niessen, C., Schermer, B., Wodarz, A., Denholm, B., Benzing, T., Iden, S., and Brinkkoetter, P.T. (2022). Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int101, 733-751. 10.1016/j.kint.2021.11.030.

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Christina Ising

• Brosseron, F., Maass, A., Kleineidam, L., Ravichandran, K.A., Gonzalez, P.G., McManus, R.M., Ising, C., Santarelli, F., Kolbe, C.C., Hasler, L.M., Wolfsgruber, S., Marquie, M., Boada, M., Orellana, A., de Rojas, I., Roske, S., Peters, O., Cosma, N.C., Cetindag, A., Wang, X., Priller, J., Spruth, E.J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Schott, B.H., Burger, K., Janowitz, D., Dichgans, M., Perneczky, R., Rauchmann, B.S., Teipel, S., Kilimann, I., Goerss, D., Laske, C., Munk, M.H., Duzel, E., Yakupov, R., Dobisch, L., Metzger, C.D., Glanz, W., Ewers, M., Dechent, P., Haynes, J.D., Scheffler, K., Roy, N., Rostamzadeh, A., Teunissen, C.E., Marchant, N.L., Spottke, A., Jucker, M., Latz, E., Wagner, M., Mengel, D., Synofzik, M., Jessen, F., Ramirez, A., Ruiz, A., Heneka, M.T., and group, D.s. (2022). Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron110, 1009-1022 e1004. 10.1016/j.neuron.2021.12.016.

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Ron Jachimowicz

• Flumann R, Hansen J, Pelzer BW, Nieper P, Lohmann T, Kisis I, Riet T, Kohlhas V, Nguyen PH, Peifer M, Abedpour N, Bosco G, Thomas RK, Kochanek M, Knufer J, Jonigkeit L, Beleggia F, Holzem A, Buttner R, Lohneis P, Meinel J, Ortmann M, Persigehl T, Hallek M, Calado DP, Chmielewski M, Klein S, Gothert JR, Chapuy B, Zevnik B, Wunderlich FT, von Tresckow B, Jachimowicz RD, Melnick AM, Reinhardt HC, Knittel G (2022). Distinct genetically-determined origins of Myd88/Bcl2-driven aggressive lymphoma rationalize targeted therapeutic intervention strategies. Blood Cancer Discov. 2022 Nov 8:BCD-22-0007. doi: 10.1158/2643-3230.BCD-22-0007. Online ahead of print. PMID: 36346827
• Flumann, R., Hansen, J., Pelzer, B., Kiss, I., Lohmann, T., Persigehl, T., Abedpour, N., Peifer, M., Buettner, R., von Tresckow, B., Jachimowicz, R., Reinhardt, H.C., and Knittel, G. (2022). Novel Autochthonous Mouse Models of Serve As Preclinical Tools to Investigate Pathogenesis and Treatment of MCD/C5 DLBCL. Blood140, 3493-3494. 10.1182/blood-2022-169607.
• Kobayashi Y, Bustos MA, Shoji Y, Jachimowicz RD, Shiloh Y, Hoon DSB (2022). Genomic Amplification of UBQLN4 Is a Prognostic and Treatment Resistance Factor. Cells. 2022 Oct 21;11(20):3311. doi: 10.3390/cells11203311. PMID: 36291176 Free PMC article.
• Ratz L, Brambillasca C, Bartke L, Huetzen MA, Goergens J, Leidecker O, Jachimowicz RD, van de Ven M, Proost N, Siteur B, de Korte-Grimmerink R, Bouwman P, Pulver EM, de Bruijn R, Isensee J, Hucho T, Pandey G, van Lohuizen M, Mallmann P, Reinhardt HC, Jonkers J, Puppe J (2022). Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer. Breast Cancer Res. 2022 Jun 17;24(1):41. doi: 10.1186/s13058-022-01534-y. PMID: 35715861
• Jachimowicz RD, Klapper W, Glehr G, Müller H, Haverkamp H, Thorns C, Hansmann ML, Möller P, Stein H, Rehberg T, von Tresckow B, Reinhardt HC, Borchmann P, Chan FC, Spang R, Scott DW, Engert A, Steidl C, Altenbuchinger M, Rosenwald A (2022). Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP. Leukemia. 2021 Dec;35(12):3589-3593. doi: 10.1038/s41375-021-01314-1. Epub 2021 Jun 10. PMID: 34112956; PMCID: PMC8632672.
• Hieber ML, Sprute R, Eichenauer DA, Hallek M, Jachimowicz RD (2022). Hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination. Infection. 2022 Feb 26:1–6. doi: 10.1007/s15010-022-01786-y. Epub ahead of print. PMID: 35218512; PMCID: PMC8881936.
• Sprute, R., Hieber, M.L., and Jachimowicz, R.D. (2022). Correspondence to: hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination. Infection50, 1617-1618. 10.1007/s15010-022-01820-z.

Frank Jessen

• Wang X, Bi Q, Lu J, Chan P, Hu X, Su L, Jessen F, Lin H, Han C, Shu N, Liu H, Han Y (2022). Difference in Amyloid Load Between Single Memory Domain and Multidomain Subjective Cognitive Decline: A Study from the SILCODE. J Alzheimers Dis. 2022;85(4):1573-1582. doi: 10.3233/JAD-215373. PMID: 34958039.
• Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Chételat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerström M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fröhlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, Gómez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lleó A, Löwenmark M, Madsen K, Maier W, Marcusson J, Marquié M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendonça A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodríguez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, Rüther E, Ruiz A, Sabri O, Sakhardande J, Sánchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schröder J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H (2022). Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. JAMA Neurol. 2022 Jan 31. doi: 10.1001/jamaneurol.2021.5216. Epub ahead of print. PMID: 35099509.
• Rostamzadeh A, Kahlert A, Kalthegener F, Jessen F (2022). Psychotherapeutic interventions in individuals at risk for Alzheimer's dementia: a systematic review. Alzheimers Res Ther. 2022 Jan 31;14(1):18. doi: 10.1186/s13195-021-00956-8. Erratum in: Alzheimers Res Ther. 2022 Mar 22;14(1):44. PMID: 35101105; PMCID: PMC8802419.
• Martino Adami PV, Orellana A, García P, Kleineidam L, Alarcón-Martín E, Montrreal L, Aguilera N, Espinosa A, Abdelnour C, Rosende-Roca M, Tartari JP, Vargas L, Mauleón A, Esteban-De Antonio E, López-Cuevas R, Dalmasso MC, Martin RC, Parveen K, Andrade Fuentes VM, Amin N, Ahmad S, Ikram MA, Lewczuk P, Kornhuber J, Peters O, Frölich L, Rüther E, Wiltfang J, Tarraga L, Boada M, Maier W, de Rojas I, Cano A, Sanabria A, Alegret M, Hernández I, Marquié M, Valero S, van Duijn CM, Wagner M, Jessen F, Schneider A, Sáez Goñi ME, Pérez AG, Ruiz A, Ramírez A (2022). Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer's type. Brain. 2022 Jan 28:awac024. doi: 10.1093/brain/awac024. Epub ahead of print. PMID: 35088840. 
• Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W Jr, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, Tosto G, Traykov L, Tremolizzo L, Tybjærg-Hansen A, Uitterlinden A, Ullgren A, Ulstein I, Valero S, Valladares O, Broeckhoven CV, Vance J, Vardarajan BN, van der Lugt A, Dongen JV, van Rooij J, van Swieten J, Vandenberghe R, Verhey F, Vidal JS, Vogelgsang J, Vyhnalek M, Wagner M, Wallon D, Wang LS, Wang R, Weinhold L, Wiltfang J, Windle G, Woods B, Yannakoulia M, Zare H, Zhao Y, Zhang X, Zhu C, Zulaica M; EADB; GR@ACE; DEGESCO; EADI; GERAD; Demgene; FinnGen; ADGC; CHARGE, Farrer LA, Psaty BM, Ghanbari M, Raj T, Sachdev P, Mather K, Jessen F, Ikram MA, de Mendonça A, Hort J, Tsolaki M, Pericak-Vance MA, Amouyel P, Williams J, Frikke-Schmidt R, Clarimon J, Deleuze JF, Rossi G, Seshadri S, Andreassen OA, Ingelsson M, Hiltunen M, Sleegers K, Schellenberg GD, van Duijn CM, Sims R, van der Flier WM, Ruiz A, Ramirez A, Lambert JC (2022). New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet.2022 Apr;54(4):412-436. doi: 10.1038/s41588-022-01024-z. Epub 2022 Apr 4. PMID: 35379992; PMCID: PMC9005347.
• Brosseron F, Maass A, Kleineidam L, Ravichandran KA, González PG, McManus RM, Ising C, Santarelli F, Kolbe CC, Häsler LM, Wolfsgruber S, Marquié M, Boada M, Orellana A, de Rojas I, Röske S, Peters O, Cosma NC, Cetindag A, Wang X, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Schott BH, Bürger K, Janowitz D, Dichgans M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Düzel E, Yakupov R, Dobisch L, Metzger CD, Glanz W, Ewers M, Dechent P, Haynes JD, Scheffler K, Roy N, Rostamzadeh A, Teunissen CE, Marchant NL, Spottke A, Jucker M, Latz E, Wagner M, Mengel D, Synofzik M, Jessen F, Ramirez A, Ruiz A, Heneka MT; DELCODE study group (2022). Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron. 2022 Mar 16;110(6):1009-1022.e4. doi: 10.1016/j.neuron.2021.12.016. Epub 2022 Jan 6. PMID: 34995486. 
• Sheng C, Yang K, He B, Li T, Wang X, Du W, Hu X, Jiang J, Jiang X, Jessen F, Han Y (2022). Cross-Cultural Longitudinal Study on Cognitive Decline (CLoCODE) for Subjective Cognitive Decline in China and Germany: A Protocol for Study Design. J Alzheimers Dis. 2022 Apr 15. doi: 10.3233/JAD-215452. Epub ahead of print. PMID: 35431240.
• Gerards M, Schild AK, Meiberth D, Rostamzadeh A, Vehreschild JJ, Wingen-Heimann S, Johannis W, Martino Adami P, Onur OA,Ramirez A, Karikari TK, Ashton NJ, Zetterberg H, Blennow K, Maier F, Jessen F (2022). Alzheimer's Disease Plasma Biomarkers Distinguish Clinical Diagnostic Groups in Memory Clinic Patients. Dement Geriatr Cogn Disord. 2022 May 3:1-11. doi: 10.1159/000524390. Epub ahead of print. PMID: 35504263.  
• Wolfsgruber S, Kleineidam L, Weyrauch AS, Barkhoff M, Röske S, Peters O, Preis L, Gref D, Spruth EJ, Altenstein S, Priller J, Fließbach K, Schneider A, Wiltfang J, Bartels C, Jessen F, Maier F, Düzel E, Metzger C, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Kilimann I, Teipel S, Laske C, Munk MH, Roy N, Spottke A, Ramirez A, Heneka MT, Brosseron F, Wagner M; DELCODE study group (2022). Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease. J Alzheimers Dis. 2022;87(2):545-555. doi: 10.3233/JAD-215416. PMID: 35275535.
• Le Guen Y, Belloy ME, Grenier-Boley B, de Rojas I, Castillo-Morales A, Jansen I, Nicolas A, Bellenguez C, Dalmasso C, Küçükali F, Eger SJ, Rasmussen KL, Thomassen JQ, Deleuze JF, He Z, Napolioni V, Amouyel P, Jessen F, Kehoe PG, van Duijn C, Tsolaki M, Sánchez-Juan P, Sleegers K, Ingelsson M, Rossi G, Hiltunen M, Sims R, van der Flier WM, Ramirez A, Andreassen OA, Frikke-Schmidt R, Williams J, Ruiz A, Lambert JC, Greicius MD; Members of the EADB, GR@ACE, DEGESCO, DemGene, GERAD, and EADI Groups, Arosio B, Benussi L, Boland A, Borroni B, Caffarra P, Daian D, Daniele A, Debette S, Dufouil C, Düzel E, Galimberti D, Giedraitis V, Grimmer T, Graff C, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Holstege H, Hort J, Jürgen D, Kuulasmaa T, van der Lugt A, Masullo C, Mecocci P, Mehrabian S, de Mendonça A, Moebus S, Nacmias B, Nicolas G, Olaso R, Papenberg G, Parnetti L, Pasquier F, Peters O, Pijnenburg YAL, Popp J, Rainero I, Ramakers I, Riedel-Heller S, Scarmeas N, Scheltens P, Scherbaum N, Schneider A, Seripa D, Soininen H, Solfrizzi V, Spalletta G, Squassina A, van Swieten J, Tegos TJ, Tremolizzo L, Verhey F, Vyhnalek M, Wiltfang J, Boada M, García-González P, Puerta R, Real LM, Álvarez V, Bullido MJ, Clarimon J, García-Alberca JM, Mir P, Moreno F, Pastor P, Piñol-Ripoll G, Molina-Porcel L, Pérez-Tur J, Rodríguez-Rodríguez E, Royo JL, Sánchez-Valle R, Dichgans M, Rujescu D (2022). Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease. JAMA Neurol. 2022 Jul 1;79(7):652-663. doi: 10.1001/jamaneurol.2022.1166. PMID: 35639372; PMCID: PMC9157381
• Billette OV, Ziegler G, Aruci M, Schütze H, Kizilirmak JM, Richter A, Altenstein S, Bartels C, Brosseron F, Cardenas-Blanco A, Dahmen P, Dechent P, Dobisch L, Fliessbach K, Freiesleben SD, Glanz W, Göerß D, Haynes JD, Heneka MT, Kilimann I, Kimmich O, Kleineidam L, Laske C, Lohse A, Rostamzadeh A, Metzger C, Munk MH, Peters O, Preis L, Priller J, Scheffler K, Schneider A, Spottke A, Spruth EJ, Ramirez A, Röske S, Roy N, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Yakupov R, Zeidman P, Jessen F, Schott BH, Düzel E, Maass A; DELCODE Study Group (2022). Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease. Neurology. Aug 23;99(8):e775-e788. doi: 10.1212/WNL.0000000000200667. Epub Jun 3. PMID: 35995589; PMCID: PMC9484732.
• Rostamzadeh A, Bohr L, Wagner M, Baethge C, Jessen F (2022). Progression of Subjective Cognitive Decline to MCI or Dementia in Relation to Biomarkers for Alzheimer Disease: A Meta-analysis. Neurology. 2022 Oct 25;99(17):e1866-e1874. doi: 10.1212/WNL.0000000000201072. Epub 2022 Aug 26. PMID: 36028322.
• Whitfield T, Demnitz-King H, Schlosser M, Barnhofer T, Frison E, Coll-Padros N, Dautricourt S, Requier F, Delarue M, Gonneaud J, Klimecki OM, Lutz A, Paly L, Salmon E, Schild AK, Walker Z, Jessen F, Chételat G, Collette F, Wirth M, Marchant NL; Medit-Ageing Research Group (2022). Effects of a mindfulness-based versus a health self-management intervention on objective cognitive performance in older adults with subjective cognitive decline (SCD): a secondary analysis of the SCD-Well randomized controlled trial. Alzheimers Res Ther. 2022 Sep 6;14(1):125. doi: 10.1186/s13195-022-01057-w. PMID: 36068621; PMCID: PMC9446839.
• Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, Vromen EM, Wightman DP, Alcolea D, Alegret M, Alvarez I, Amouyel P, Athanasiu L, Bahrami S, Bailly H, Belbin O, Bergh S, Bertram L, Biessels GJ, Blennow K, Blesa R, Boada M, Boland A, Buerger K, Carracedo Á, Cervera-Carles L, Chene G, Claassen JAHR, Debette S, Deleuze JF, de Deyn PP, Diehl-Schmid J, Djurovic S, Dols-Icardo O, Dufouil C, Duron E, Düzel E; EADB consortium, Fladby T, Fortea J, Frölich L, García-González P, Garcia-Martinez M, Giegling I, Goldhardt O, Gobom J, Grimmer T, Haapasalo A, Hampel H, Hanon O, Hausner L, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herukka SK, Holstege H, Jarholm J, Kern S, Knapskog AB, Koivisto AM, Kornhuber J, Kuulasmaa T, Lage C, Laske C, Leinonen V, Lewczuk P, Lleó A, de Munain AL, Lopez-Garcia S, Maier W, Marquié M, Mol MO, Montrreal L, Moreno F, Moreno-Grau S, Nicolas G, Nöthen MM, Orellana A, Pålhaugen L, Papma JM, Pasquier F, Perneczky R, Peters O, Pijnenburg YAL, Popp J, Posthuma D, Pozueta A, Priller J, Puerta R, Quintela I, Ramakers I, Rodriguez-Rodriguez E, Rujescu D, Saltvedt I, Sanchez-Juan P, Scheltens P, Scherbaum N, Schmid M, Schneider A, Selbæk G, Selnes P, Shadrin A, Skoog I, Soininen H, Tárraga L, Teipel S; GR@ACE study group, Tijms B, Tsolaki M, Van Broeckhoven C, Van Dongen J, van Swieten JC, Vandenberghe R, Vidal JS, Visser PJ, Vogelgsang J, Waern M, Wagner M, Wiltfang J, Wittens MMJ, Zetterberg H, Zulaica M, van Duijn CM, Bjerke M, Engelborghs S, Jessen F, Teunissen CE, Pastor P, Hiltunen M, Ingelsson M, Andreassen OA, Clarimón J, Sleegers K, Ruiz A, Ramirez A, Cruchaga C, Lambert JC, van der Flier W (2022). Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathol. 2022 Nov;144(5):821-842. doi: 10.1007/s00401-022-02454-z. Epub 2022 Sep 6. PMID: 36066633; PMCID: PMC9547780.
• Böttcher A, Zarucha A, Köbe T, Gaubert M, Höppner A, Altenstein S, Bartels C, Buerger K, Dechent P, Dobisch L, Ewers M, Fliessbach K, Freiesleben SD, Frommann I, Haynes JD, Janowitz D, Kilimann I, Kleineidam L, Laske C, Maier F, Metzger C, Munk MHJ, Perneczky R, Peters O, Priller J, Rauchmann BS, Roy N, Scheffler K, Schneider A, Spottke A, Teipel SJ, Wiltfang J, Wolfsgruber S, Yakupov R, Düzel E, Jessen F, Röske S, Wagner M, Kempermann G, Wirth M (2022). Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults. Front Psychol. 2022 Aug 25;13:945709. doi: 10.3389/fpsyg.2022.945709. PMID: 36092026; PMCID: PMC9454948.
• Altomare, D., Collij, L., Caprioglio, C., Scheltens, P., van Berckel, B.N.M., Alves, I.L., Berkhof, J., de Gier, Y., Garibotto, V., Moro, C., Poitrine, L., Delrieu, J., Payoux, P., Saint-Aubert, L., Molinuevo, J.L., Grau-Rivera, O., Gispert, J.D., Minguillon, C., Fauria, K., Sanchez, M.F., Radoi, A., Drzezga, A., Jessen, F., Escher, C., Zeyen, P., Nordberg, A., Savitcheva, I., Jelic, V., Walker, Z., Lee, H.Y., Lee, L., Demonet, J.F., Plaza Wuthrich, S., Gismondi, R., Farrar, G., Barkhof, F., Stephens, A.W., Frisoni, G.B., and Consortium, A. (2022). Description of a European memory clinic cohort undergoing amyloid-PET: The AMYPAD Diagnostic and Patient Management Study. Alzheimers Dement. 10.1002/alz.12696.
• Berron, D., Ziegler, G., Vieweg, P., Billette, O., Gusten, J., Grande, X., Heneka, M.T., Schneider, A., Teipel, S., Jessen, F., Wagner, M., and Duzel, E. (2022). Feasibility of Digital Memory Assessments in an Unsupervised and Remote Study Setting. Front Digit Health4, 892997. 10.3389/fdgth.2022.892997.
• Boada, M., Rodrigo, A., Jessen, F., Wimblad, B., Kramberger, M.G., Visser, P.J., Simo, R., Rodriguez-Gomez, O., Ciudin, A., Georges, J., Dumas, A., Maguire, P., Krivec, D., Wimo, A., Valero, S., Alegret, M., Jamilis, L., Zwan, M., Sannemann, L., Arrufat, J., Stomrud, E., Johansson, G., Shering, C., Glaysher, B., Stewart, N., Belger, M., Iradier, F., Campo, L., and consortium, M. (2022). Complementary pre-screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project. Alzheimers Dement18, 1119-1127. 10.1002/alz.12441.
• Caprioglio, C., Garibotto, V., Jessen, F., Frolich, L., Allali, G., Assal, F., Frisoni, G.B., Altomare, D., and European Alzheimer's Disease, C. (2022). The Clinical Use of Alzheimer's Disease Biomarkers in Patients with Mild Cognitive Impairment: A European Alzheimer's Disease Consortium Survey. J Alzheimers Dis89, 535-551. 10.3233/JAD-220333.
• Collij, L.E., Farrar, G., Vallez Garcia, D., Bader, I., Shekari, M., Lorenzini, L., Pemberton, H., Altomare, D., Pla, S., Loor, M., Markiewicz, P., Yaqub, M., Buckley, C., Frisoni, G.B., Nordberg, A., Payoux, P., Stephens, A., Gismondi, R., Visser, P.J., Ford, L., Schmidt, M., Birck, C., Georges, J., Mett, A., Walker, Z., Boada, M., Drzezga, A., Vandenberghe, R., Hanseeuw, B., Jessen, F., Scholl, M., Ritchie, C., Lopes Alves, I., Gispert, J.D., and Barkhof, F. (2022). The amyloid imaging for the prevention of Alzheimer's disease consortium: A European collaboration with global impact. Front Neurol13, 1063598. 10.3389/fneur.2022.1063598.
• Demnitz-King, H., Gonneaud, J., Klimecki, O.M., Chocat, A., Collette, F., Dautricourt, S., Jessen, F., Krolak-Salmon, P., Lutz, A., Morse, R.M., Molinuevo, J.L., Poisnel, G., Touron, E., Wirth, M., Walker, Z., Chetelat, G., Marchant, N.L., and Medit-Ageing Research, G. (2022). Association of Self-reflection With Cognition and Brain Health in Cognitively Unimpaired Older Adults. Neurology99, e1422-e1431. 10.1212/WNL.0000000000200951.
• Duzel, E., Ziegler, G., Berron, D., Maass, A., Schutze, H., Cardenas-Blanco, A., Glanz, W., Metzger, C., Dobisch, L., Reuter, M., Spottke, A., Brosseron, F., Fliessbach, K., Heneka, M.T., Laske, C., Peters, O., Priller, J., Spruth, E.J., Ramirez, A., Speck, O., Schneider, A., Teipel, S., Kilimann, I., Jens, W., Schott, B.H., Preis, L., Gref, D., Maier, F., Munk, M.H., Roy, N., Ballarini, T., Yakupov, R., Haynes, J.D., Dechent, P., Scheffler, K., Wagner, M., and Jessen, F.(2022). Amyloid pathology but not APOE epsilon4 status is permissive for tau-related hippocampal dysfunction. Brain145, 1473-1485. 10.1093/brain/awab405.
• Gaubert, M., Dell'Orco, A., Lange, C., Garnier-Crussard, A., Zimmermann, I., Dyrba, M., Duering, M., Ziegler, G., Peters, O., Preis, L., Priller, J., Spruth, E.J., Schneider, A., Fliessbach, K., Wiltfang, J., Schott, B.H., Maier, F., Glanz, W., Buerger, K., Janowitz, D., Perneczky, R., Rauchmann, B.S., Teipel, S., Kilimann, I., Laske, C., Munk, M.H., Spottke, A., Roy, N., Dobisch, L., Ewers, M., Dechent, P., Haynes, J.D., Scheffler, K., Duzel, E., Jessen, F., Wirth, M., and group, D.s. (2022). Performance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia. Front Psychiatry13, 1010273. 10.3389/fpsyt.2022.1010273.
• Janssen, O., Jansen, W.J., Vos, S.J.B., Boada, M., Parnetti, L., Gabryelewicz, T., Fladby, T., Molinuevo, J.L., Villeneuve, S., Hort, J., Epelbaum, S., Lleo, A., Engelborghs, S., van der Flier, W.M., Landau, S., Popp, J., Wallin, A., Scheltens, P., Rikkert, M.O., Snyder, P.J., Rowe, C., Chetelat, G., Ruiz, A., Marquie, M., Chipi, E., Wolfsgruber, S., Heneka, M., Boecker, H., Peters, O., Jarholm, J., Rami, L., Tort-Merino, A., Binette, A.P., Poirier, J., Rosa-Neto, P., Cerman, J., Dubois, B., Teichmann, M., Alcolea, D., Fortea, J., Sanchez-Saudinos, M.B., Ebenau, J., Pocnet, C., Eckerstrom, M., Thompson, L., Villemagne, V., Buckley, R., Burnham, S., Delarue, M., Freund-Levi, Y., Wallin, A.K., Ramakers, I., Tsolaki, M., Soininen, H., Hampel, H., Spiru, L., Alzheimer's Disease Neuroimaging, I., group, F.s., group, P.-A.r., Tijms, B., Ossenkoppele, R., Verhey, F.R.J., Jessen, F., and Visser, P.J. (2022). Characteristics of subjective cognitive decline associated with amyloid positivity. Alzheimers Dement18, 1832-1845. 10.1002/alz.12512.
• Kambeitz-Ilankovic, L., Rzayeva, U., Volkel, L., Wenzel, J., Weiske, J., Jessen, F., Reininghaus, U., Uhlhaas, P.J., Alvarez-Jimenez, M., and Kambeitz, J. (2022). A systematic review of digital and face-to-face cognitive behavioral therapy for depression. NPJ Digit Med5, 144. 10.1038/s41746-022-00677-8.
• Kleineidam, L., Wolfsgruber, S., Weyrauch, A.S., Zulka, L.E., Forstmeier, S., Roeske, S., van den Bussche, H., Kaduszkiewicz, H., Wiese, B., Weyerer, S., Werle, J., Fuchs, A., Pentzek, M., Brettschneider, C., Konig, H.H., Weeg, D., Bickel, H., Luppa, M., Rodriguez, F.S., Freiesleben, S.D., Erdogan, S., Unterfeld, C., Peters, O., Spruth, E.J., Altenstein, S., Lohse, A., Priller, J., Fliessbach, K., Kobeleva, X., Schneider, A., Bartels, C., Schott, B.H., Wiltfang, J., Maier, F., Glanz, W., Incesoy, E.I., Butryn, M., Duzel, E., Buerger, K., Janowitz, D., Ewers, M., Rauchmann, B.S., Perneczky, R., Kilimann, I., Gorss, D., Teipel, S., Laske, C., Munk, M.H.J., Spottke, A., Roy, N., Brosseron, F., Heneka, M.T., Ramirez, A., Yakupov, R., Scherer, M., Maier, W., Jessen, F., Riedel-Heller, S.G., and Wagner, M. (2022). Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve. Front Psychol13, 957308. 10.3389/fpsyg.2022.957308.
• Melo van Lent, D., Egert, S., Wolfsgruber, S., Kleineidam, L., Weinhold, L., Wagner-Thelen, H., Stoffel-Wagner, B., Bickel, H., Wiese, B., Weyerer, S., Pentzek, M., Jessen, F., Schmid, M., Maier, W., Scherer, M., Riedel-Heller, S.G., Ramirez, A., and Wagner, M. (2022). Low Serum Vitamin D Status Is Associated with Incident Alzheimer's Dementia in the Oldest Old. Nutrients15. 10.3390/nu15010061.
• Oedekoven, C., Egeri, L., Jessen, F., Wagner, M., and Dodel, R. (2022). Subjective cognitive decline in idiopathic Parkinson s disease: A systematic review. Ageing Res Rev74, 101508. 10.1016/j.arr.2021.101508.
• Ophey, A., Krohm, F., Kalbe, E., Greuel, A., Drzezga, A., Tittgemeyer, M., Timmermann, L., Jessen, F., Eggers, C., and Maier, F. (2022). Neural correlates and predictors of subjective cognitive decline in patients with Parkinson's disease. Neurol Sci43, 3153-3163. 10.1007/s10072-021-05734-w.
• Polcher, A., Wolfsgruber, S., Peters, O., Frolich, L., Wiltfang, J., Kornhuber, J., Hull, M., Ruther, E., Lewczuk, P., Maier, W., Jessen, F., and Wagner, M. (2022). A Comparison of Operational Definitions for Mild Cognitive Impairment. J Alzheimers Dis88, 1663-1678. 10.3233/JAD-215548.
• Schladitz, K., Weitzel, E.C., Lobner, M., Soltmann, B., Jessen, F., Schmitt, J., Pfennig, A., Riedel-Heller, S.G., and Guhne, U. (2022). Demands on Health Information and Clinical Practice Guidelines for Patients from the Perspective of Adults with Mental Illness and Family Members: A Qualitative Study with In-Depth Interviews. Int J Environ Res Public Health19. 10.3390/ijerph192114262.
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Hamid Kashkar

• Simpson DS, Pang J, Weir A, Kong IY, Fritsch M, Rashidi M, Cooney JP, Davidson KC, Speir M, Djajawi TM, Hughes S, Mackiewicz L, Dayton M, Anderton H, Doerflinger M, Deng Y, Huang AS, Conos SA, Tye H, Chow SH, Rahman A, Norton RS, Naderer T, Nicholson SE, Burgio G, Man SM, Groom JR, Herold MJ, Hawkins ED, Lawlor KE, Strasser A, Silke J, Pellegrini M, Kashkar H, Feltham R, Vince JE (2022). Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway. Immunity. 2022 Mar 8;55(3):423-441.e9. doi: 10.1016/j.immuni.2022.01.003. Epub 2022 Feb 8. PMID: 35139355; PMCID: PMC8822620. 
• Daoud M, Broxtermann PN, Schorn F, Werthenbach JP, Seeger JM, Schiffmann LM, Brinkmann K, Vucic D, Tüting T, Mauch C, Kulms D, Zigrino P, Kashkar H (2022).XIAP promotes melanoma growth by inducing tumour neutrophil infiltration. EMBO Rep. 2022 Apr 19:e53608. doi: 10.15252/embr.202153608. Epub ahead ofprint. PMID: 35437868.
• Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling CD, Nieper P, Feldmann T, Merkel O, Lorsy E, da Palma Guerreiro A, von Jan J, Kisis I, Wasserburger E, Claasen J, Faitschuk-Meyer E, Altmüller J, Nürnberg P, Yang TP, Lienhard M, Herwig R, Kreuzer KA, Pallasch CP, Buettner R, Schäfer SC, Hartley J, Abken H, Peifer M, Kashkar H, Knittel G, Eichhorst B, Ullrich RT, Herling M, Reinhardt HC, Hallek M, Schweiger MR, Frenzel LP (2022). Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies. Blood. 2022 Jun 15:blood.2021014304. doi: 10.1182/blood.2021014304. Epub ahead of print. PMID: 35704690.
• Pindzola GM, Razzaghi R, Tavory RN, Nguyen HT, Morris V, Li M, Agarwal S, Huang B, Okada T, Reinhardt HC, Knittel G, Kashkar H, Young RM, Pittaluga S, Muppidi JR (2022). Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma. Blood. 2022 Sep 8;140(10):1119-1131. doi: 10.1182/blood.2022015926
• Flores-Romero, H., Hohorst, L., John, M., Albert, M.C., King, L.E., Beckmann, L., Szabo, T., Hertlein, V., Luo, X., Villunger, A., Frenzel, L.P., Kashkar, H., and Garcia-Saez, A.J. (2022). BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. Embo J41. ARTN e108690. 10.15252/embj.2021108690.
• Kieckhofer, E., Slaats, G.G., Ebert, L.K., Albert, M.C., Dafinger, C., Kashkar, H., Benzing, T., and Schermer, B. (2022). Primary cilia suppress Ripk3-mediated necroptosis. Cell Death Discov8, 477. 10.1038/s41420-022-01272-2.
• Knipper, K., Lyu, S.I., Goebel, H., Damanakis, A.I., Zhao, Y., Bruns, C.J., Schmidt, T., Kashkar, H., Quaas, A., Schiffmann, L.M., Popp, F.C., and Group, P.S. (2022). X-linked inhibitor of apoptosis protein is a prognostic marker for a favorable outcome in three identified subsets in resectable adenocarcinoma of the pancreas. J Cancer Res Clin Oncol. 10.1007/s00432-022-04476-2.

Peter Kloppenburg

• Gaziano, I., Corneliussen, S., Biglari, N., Neuhaus, R., Shen, L., Sotelo-Hitschfeld, T., Klemm, P., Steuernagel, L., De Solis, A.J., Chen, W., Wunderlich, F.T., Kloppenburg, P., and Bruning, J.C. (2022). Dopamine-inhibited POMCDrd2+ neurons in the ARC acutely regulate feeding and body temperature. Jci Insight7. 10.1172/jci.insight.162753.
• Overhoff, M., Tellkamp, F., Hess, S., Tolve, M., Tutas, J., Faerfers, M., Ickert, L., Mohammadi, M., De Bruyckere, E., Kallergi, E., Delle Vedove, A., Nikoletopoulou, V., Wirth, B., Isensee, J., Hucho, T., Puchkov, D., Isbrandt, D., Krueger, M., Kloppenburg, P., and Kononenko, N.L. (2022). Autophagy regulates neuronal excitability by controlling cAMP/protein kinase A signaling at the synapse. EMBO J41, e110963. 10.15252/embj.2022110963.
• Siller, A., Hofer, N.T., Tomagra, G., Burkert, N., Hess, S., Benkert, J., Gaifullina, A., Spaich, D., Duda, J., Poetschke, C., Vilusic, K., Fritz, E.M., Schneider, T., Kloppenburg, P., Liss, B., Carabelli, V., Carbone, E., Ortner, N.J., and Striessnig, J. (2022). beta2-subunit alternative splicing stabilizes Cav2.3 Ca(2+) channel activity during continuous midbrain dopamine neuron-like activity. Elife11. 10.7554/eLife.67464.

Natalia Kononenko

• Camblor-Perujo, S., and Kononenko, N.L. (2022). Brain-specific functions of the endocytic machinery. FEBS J289, 2219-2246. 10.1111/febs.15897.
• Overhoff, M., Tellkamp, F., Hess, S., Tolve, M., Tutas, J., Faerfers, M., Ickert, L., Mohammadi, M., De Bruyckere, E., Kallergi, E., Delle Vedove, A., Nikoletopoulou, V., Wirth, B., Isensee, J., Hucho, T., Puchkov, D., Isbrandt, D., Krueger, M., Kloppenburg, P., and Kononenko, N.L. (2022). Autophagy regulates neuronal excitability by controlling cAMP/protein kinase A signaling at the synapse. EMBO J41, e110963. 10.15252/embj.2022110963.
• Sona, C., Yeh, Y.T., Patsalos, A., Halasz, L., Yan, X., Kononenko, N.L., Nagy, L., and Poy, M.N. (2022). Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes. Jci Insight7. ARTN e153136. 10.1172/jci.insight.153136.

Thomas Krieg

• Jerjen R, Nikpour M, Krieg T, Denton CP, Saracino AM (2022). Systemic sclerosis in adults. Part II: Management and therapeutics. J Am Acad Dermatol. 2022 87(5):957-978. doi: 10.1016/j.jaad.2021.10.066. Epub 2022 Feb 4. PMID: 35131401.
• Rosendahl AH, Schönborn K, Krieg T (2022). Pathophysiology of systemic sclerosis (scleroderma). Kaohsiung J Med Sci. 2022 Mar;38(3):187-195. doi: 10.1002/kjm2.12505. Epub 2022 Mar 2. PMID: 35234358.
• Bruni C, Buch MH, Furst DE, De Luca G, Djokovic A, Dumitru RB, Giollo A, Polovina M, Steelandt A, Bratis K, Suliman YA, Milinkovic I, Baritussio A, Hasan G, Xintarakou A, Isomura Y, Markousis-Mavrogenis G, Tofani L, Mavrogeni S, Gargani L, Caforio AL, Tschöpe C, Ristic A, Klingel K, Plein S, Behr ER, Allanore Y, Kuwana M, Denton CP, Khanna D, Krieg T, Marcolongo R, Galetti I, Zanatta E, Tona F, Seferovic P, Matucci-Cerinic M. (2022). Primary systemic sclerosis heart involvement: A systematic literature review and preliminary data-driven, consensus-based WSF/HFA definition. J Scleroderma Relat Disord. 2022 Feb;7(1):24-32. doi: 10.1177/23971983211053246. Epub 2021 Oct 26. PMID: 35386946.
• Baldini C, Arnaud L, Avčin T, Beretta L, Bellocchi C, Bouillot C, Burmester GR, Cavagna L, Cutolo M, de Vries-Bouwstra JK, Doria A, Ferro F, Fonseca JE, Fonzetti S, Fulvio G, Galetti I, Gottenberg JE, Hachulla E, Krieg T, La Rocca G, Martin T, Matucci-Cerinic M, Moinzadeh P, Montecucco C, Mosca M, Mouthon L, Müller-Ladner U, Rednic S, Smith V, Talarico R, van Laar JM, Vieira A, Romão VC, Mariette X (2022). Sjögren's syndrome and other rare and complex connective tissue diseases: an intriguing liaison. Clin Exp Rheumatol 2022 May;40 Suppl 134(5):103-112. doi: 10.55563/clinexprheumatol/3y0hqs. Epub 2022 Mar 21. PMID: 35349420.
• Blank, N., Schmalzing, M., Moinzadeh, P., Oberste, M., Siegert, E., Muller-Ladner, U., Riemekasten, G., Gunther, C., Kotter, I., Zeidler, G., Pfeiffer, C., Juche, A., Jandova, I., Ehrchen, J., Susok, L., Schmeiser, T., Sunderkotter, C., Distler, J.H.W., Worm, M., Kreuter, A., Keysser, G., Lorenz, H.M., Krieg, T., Hunzelmann, N., Henes, J., and German Network for Systemic, S. (2022). Autologous hematopoietic stem cell transplantation improves long-term survival-data from a national registry. Arthritis Res Ther24, 258. 10.1186/s13075-022-02948-x.
• Rosendahl, A.S., Schonborn, K., Baar, T., Kleinenkuhnen, N., Tresch, A., Eckes, B., Moinzadeh, P., and Krieg, T.(2022). Single cell RNA sequencing reveals specific subsets in Systemic Sclerosis fibroblast cultures. J Invest Dermatol142, S182-S182.
• Talarico, R., Aguilera, S., Alexander, T., Amoura, Z., Antunes, A.M., Arnaud, L., Avcin, T., Beretta, L., Bombardieri, S., Burmester, G.R., Cannizzo, S., Cavagna, L., Chaigne, B., Cornet, A., Costedoat-Chalumeau, N., Doria, A., Ferraris, A., Fischer-Betz, R., Fonseca, J.E., Frank, C., Gaglioti, A., Galetti, I., Grunert, J., Guimaraes, V., Hachulla, E., Houssiau, F., Iaccarino, L., Krieg, T., Limper, M., Malfait, F., Mariette, X., Marinello, D., Martin, T., Matthews, L., Matucci-Cerinic, M., Meyer, A., Montecucco, C., Mouthon, L., Muller-Ladner, U., Rednic, S., Romao, V.C., Schneider, M., Smith, V., Sulli, A., Tamirou, F., Taruscio, D., Taulaigo, A.V., Terol, E., Tincani, A., Ticciati, S., Turchetti, G., van Hagen, P.M., van Laar, J.M., Vieira, A., de Vries-Bouwstra, J.K., Cutolo, M., and Mosca, M. (2022). Publisher Correction: The impact of COVID-19 on rare and complex connective tissue diseases: the experience of ERN ReCONNET. Nat Rev Rheumatol18, 734. 10.1038/s41584-022-00862-9.

Martin Krönke

• Gluschko, A., Farid, A., Herb, M., Grumme, D., Kronke, M., and Schramm, M. (2022). Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways. Autophagy18, 1090-1107. 10.1080/15548627.2021.1969765.
• Morris CR, Habibovic A, Dustin CM, Schiffers C, Lin MC, Ather JL, Janssen-Heininger YMW, Poynter ME, Utermohlen O, Krönke M, van der Vliet A (2022). Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease. Mucosal Immunol. 2022 May;15(5):977-989. doi: 10.1038/s41385-022-00530-x. Epub 2022 Jun 2.PMID: 35654836
• Herb M, Gluschko A, Farid A, Krönke M (2022) When the Phagosome Gets Leaky: Pore-Forming Toxin-Induced Non-Canonical Autophagy (PINCA). Front Cell Infect Microbiol. 2022 Mar 17;12:834321. doi: 10.3389/fcimb.2022.834321. eCollection 2022.PMID: 35372127 

Marcus Krüger

• Izquierdo E, Vorholt D, Blakemore SJ, Sackey B, Nolte JL, Barbarino V, Schmitz JH, Nickel N, Bachurski D, Lobastova L, Nikolic M, Michalik M, Brinker R, Merkel O, Franitza M, Georgomanolis T, Neuhaus R, Koch MRK, Nasada N, Knittel G, Chapuy B, Ludwig N, Meese E, Frenzel LP, Reinhardt HC, Peifer M, Rebollido-Rios R, Bruns H, Krüger M, Hallek M,Pallasch CP (2022).Extracellular vesicles and PDL1 suppress macrophages inducing therapy resistance in TP53-deficient B-cell malignancies. Blood. 2022 Mar 28:blood.2021014007. doi: 10.1182/blood.2021014007. Epub ahead of print. PMID: 35344582.
• Croon M, Szczepanowska K, Popovic M, Lienkamp C, Senft K, Brandscheid CP, Bock T, Gnatzy-Feik L, Ashurov A, Acton RJ, Kaul H, Pujol C, Rosenkranz S, Krüger M, Trifunovic A (2022). FGF21 modulates mitochondrial stress response in cardiomyocytes only under mild mitochondrial dysfunction.Sci Adv. 2022 Apr 8;8(14):eabn7105. doi: 10.1126/sciadv.abn7105. Epub 2022 Apr 6. PMID: 35385313; PMCID: PMC8986112.
• Thievessen I, Suhr F, Vergarajauregui S, Böttcher RT, Brixius K, Rosenberger G, Dewald O, Fleischmann BK, Ghanem A, Krüger M, Engel FB, Fabry B, Bloch W, Fässler R (2022).The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load. Curr Biol. 2022 Jul 25;32(14):3033-3047.e9. doi: 10.1016/j.cub.2022.05.047. Epub 2022 Jun 9. PMID: 35688156.
• Knabbe J, Protzmann J, Schneider N, Berger M, Dannehl D, Wei S, Strahle C, Tegtmeier M, Jaiswal A, Zheng H, Krüger M, Rohr K, Spanagel R, Bilbao A, Engelhardt M, Scholz H, Cambridge SB (2022). Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2122477119. doi: 10.1073/pnas.2122477119. Epub 2022 Jun 14. PMID: 35700362; PMCID: PMC9231489.
• Das A, Thapa P, Santiago U, Shanmugam N, Banasiak K, Dąbrowska K, Nolte H, Szulc NA, Gathungu RM, Cysewski D, Krüger M, Dadlez M, Nowotny M, Camacho CJ, Hoppe T, Pokrzywa W (2022). A heterotypic assembly mechanism regulates CHIP E3 ligase activity. EMBO J. 2022 Aug 1;41(15):e109566. doi: 10.15252/embj.2021109566. Epub 2022 Jun 28. PMID: 35762422. 
• Clemen, C.S., Schmidt, A., Winter, L., Canneva, F., Wittig, I., Becker, L., Coras, R., Berwanger, C., German Mouse Clinic, C., Hofmann, A., Eggers, B., Marcus, K., Gailus-Durner, V., Fuchs, H., de Angelis, M.H., Kruger, M., von Horsten, S., Eichinger, L., and Schroder, R. (2022). N471D WASH complex subunit strumpellin knock-in mice display mild motor and cardiac abnormalities and BPTF and KLHL11 dysregulation in brain tissue. Neuropathol Appl Neurobiol48, e12750. 10.1111/nan.12750.
• Koser, F., Hobbach, A.J., Abdellatif, M., Herbst, V., Turk, C., Reinecke, H., Kruger, M., Sedej, S., and Linke, W.A. (2022). Acetylation and phosphorylation changes to cardiac proteins in experimental HFpEF due to metabolic risk reveal targets for treatment. Life Sci309, 120998. 10.1016/j.lfs.2022.120998.
• Lennermann, D.C., Pepin, M.E., Grosch, M., Konrad, L., Kemmling, E., Hartmann, J., Nolte, J.L., Clauder-Munster, S., Kayvanpour, E., Sedaghat-Hamedani, F., Haas, J., Meder, B., van den Boogaard, M., Amin, A.S., Dewenter, M., Kruger, M., Steinmetz, L.M., Backs, J., and van den Hoogenhof, M.M.G. (2022). Deep phenotyping of two preclinical mouse models and a cohort of RBM20 mutation carriers reveals no sex-dependent disease severity in RBM20 cardiomyopathy. Am J Physiol Heart Circ Physiol323, H1296-H1310. 10.1152/ajpheart.00328.2022.
• Manta, C.P., Leibing, T., Friedrich, M., Nolte, H., Adrian, M., Schledzewski, K., Krzistetzko, J., Kirkamm, C., David Schmid, C., Xi, Y., Stojanovic, A., Tonack, S., de la Torre, C., Hammad, S., Offermanns, S., Kruger, M., Cerwenka, A., Platten, M., Goerdt, S., and Geraud, C. (2022). Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression. Circulation146, 1783-1799. 10.1161/CIRCULATIONAHA.121.058615.
• Rinschen, M.M., Palygin, O., El-Meanawy, A., Domingo-Almenara, X., Palermo, A., Dissanayake, L.V., Golosova, D., Schafroth, M.A., Guijas, C., Demir, F., Jaegers, J., Gliozzi, M.L., Xue, J., Hoehne, M., Benzing, T., Kok, B.P., Saez, E., Bleich, M., Himmerkus, N., Weisz, O.A., Cravatt, B.F., Kruger, M., Benton, H.P., Siuzdak, G., and Staruschenko, A. (2022). Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension. Nat Commun13, 4099. 10.1038/s41467-022-31670-0.
• Sen, A., Kallabis, S., Gaedke, F., Jungst, C., Boix, J., Nuchel, J., Maliphol, K., Hofmann, J., Schauss, A.C., Kruger, M., Wiesner, R.J., and Pla-Martin, D. (2022). Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA. Nat Commun13, 6704. 10.1038/s41467-022-34205-9.
• Vesting, A.J., Jais, A., Klemm, P., Steuernagel, L., Wienand, P., Fog-Tonnesen, M., Hvid, H., Schumacher, A.L., Kukat, C., Nolte, H., Georgomanolis, T., Altmuller, J., Pasparakis, M., Schmidt, A., Kruger, M., Supprian, M.S., Waisman, A., Straub, B.K., Raschzok, N., Bernier, M., Birkenfeld, A.L., Hovelmeyer, N., Bruning, J.C., and Wunderlich, F.T. (2022). NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition. Mol Metab66, 101626. 10.1016/j.molmet.2022.101626.

Leo Kurian

• Galanjuk, S., Zuhr, E., Donmez, A., Bartsch, D., Kurian, L., Tigges, J., and Fritsche, E. (2022). The Human Induced Pluripotent Stem Cell Test as an Alternative Method for Embryotoxicity Testing. Int J Mol Sci23. 10.3390/ijms23063295.
• Josipovic, N., Ebbesen, K.K., Zirkel, A., Danieli-Mackay, A., Dieterich, C., Kurian, L., Hansen, T.B., and Papantonis, A. (2022). circRAB3IP modulates cell proliferation by reorganizing gene expression and mRNA processing in a paracrine manner. RNA28, 1481-1495. 10.1261/rna.079195.122.

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Thomas Langer

• Wani GA, Sprenger HG, Ndoci K, Chandragiri S, Acton RJ, Schatton D, Kochan SMV, Sakthivelu V, Jevtic M, Seeger JM, Müller S, Giavalisco P, Rugarli EI, Motori E, Langer T, Bergami M (2022). Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.Cell Rep. 2022 Feb 15;38(7):110370. doi: 10.1016/j.celrep.2022.110370. PMID: 35172139. 
• Schatton D, Di Pietro G, Szczepanowska K, Veronese M, Marx MC, Braunöhler K, Barth E, Müller S, Giavalisco P, Langer T, Trifunovic A, Rugarli EI (2022). CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife. 2022 May 13;11:e74552. doi: 10.7554/eLife.74552. Epub ahead of print. PMID: 35559794.
• Patron, M., Tarasenko, D., Nolte, H., Kroczek, L., Ghosh, M., Ohba, Y., Lasarzewski, Y., Ahmadi, Z.A., Cabrera-Orefice, A., Eyiama, A., Kellermann, T., Rugarli, E.I., Brandt, U., Meinecke, M., Langer, T(2022). Regulation of mitochondrial proteostasis by the proton gradient. EMBO J. 2022 Aug 1:e110476. Online ahead of prin,t.doi: 10.15252/embj.2021110476.
• Ahola S, Rivera Mejías P, Hermans S, Chandragiri S, Giavalisco P, Nolte H, Langer T (2022). OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy. Cell Metab. 2022 Nov 1;34(11):1875-1891.e7. doi: 10.1016/j.cmet.2022.08.017. Epub 2022 Sep 15. PMID: 36113464.
• Willenborg, S., Sanin, D.E., Jais, A., Ding, X., Ulas, T., Nuchel, J., Popovic, M., MacVicar, T., Langer, T. , Schultze, J.L., Roers, A., Pearce, E.J., Bruning, J.C., Trifunovic, A., and Eming, S.A. (2022). Metabolic reprogramming coordinates dynamics of myeloid cell function in skin repair. Exp Dermatol31, E62-E62.

Marius Lemberg

• Bock, J., Kuhnle, N., Knopf, J.D., Landscheidt, N., Lee, J.G., Ye, Y., and Lemberg, M.K. (2022). Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation. Cell Rep40. ARTN 111175. 10.1016/j.celrep.2022.111175.
• Engberg, O., Ulbricht, D., Dobel, V., Siebert, V., Frie, C., Penk, A., Lemberg, M.K., and Huster, D. (2022). Rhomboid-catalyzed intramembrane proteolysis requires hydrophobic matching with the surrounding lipid bilayer. Sci Adv8. ARTN eabq8303. 10.1126/sciadv.abq8303.
• Pechincha, C., Groessl, S., Kalis, R., de Almeida, M., Zanotti, A., Wittmann, M., Schneider, M., de Campos, R.P., Rieser, S., Brandstetter, M., Schleiffer, A., Muller-Decker, K., Helm, D., Jabs, S., Haselbach, D., Lemberg, M.K., Zuber, J., and Palm, W. (2022). Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins. Science378, 39-+. ARTN eabn5637. 10.1126/science.abn5637.
• Siebert, V., Silber, M., Heuten, E., Muhle-Goll, C., and Lemberg, M.K. (2022). Cleavage of mitochondrial homeostasis regulator PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state. J Biol Chem298. ARTN 102321. 10.1016/j.jbc.2022.102321.
• Zanotti, A., Coelho, J.P.L., Kaylani, D., Singh, G., Tauber, M., Hitzenberger, M., Avci, D., Zacharias, M., Russell, R.B., Lemberg, M.K., and Feige, M.J. (2022). The human signal peptidase complex acts as a quality control enzyme for membrane proteins. Science378, 996-1000. 10.1126/science.abo5672.

Maria Leptin

• Kakanj, P., Bhide, S., Moussian, B., and Leptin, M. (2022). Autophagy-mediated plasma membrane removal promotes the formation of epithelial syncytia. EMBO J41, e109992. 10.15252/embj.2021109992.
• Ríos-Barrera, L.D., and Leptin, M. (2022). An endosome-associated actin network involved in directed apical plasma membrane growth. Journal of Cell Biology221. ARTN e202106124. 10.1083/jcb.202106124.

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Ivan Matic

• Longarini EJ, Matic I (2022). The fast-growing business of Serine ADP-ribosylation. DNA Repair (Amst). Oct;118:103382. doi: 10.1016/j.dnarep.2022.103382. Epub Jul 29. PMID: 35963141.
• Luscher, B., Ahel, I., Altmeyer, M., Ashworth, A., Bai, P.T., Chang, P., Cohen, M., Corda, D., Dantzer, F., Daugherty, M.D., Dawson, T.M., Dawson, V.L., Deindl, S., Fehr, A.R., Feijs, K.L.H., Filippov, D.V., Gagné, J.P., Grimaldi, G., Guettler, S., Hoch, N.C., Hottiger, M.O., Korn, P., Kraus, W.L., Ladurner, A., Lehtiö, L., Leung, A.K.L., Lord, C.J., Mangerich, A., Matic, I., Matthews, J., Moldovan, G.L., Moss, J., Natoli, G., Nielsen, M.L., Niepel, M., Nolte, F., Pascal, J., Paschal, B.M., Pawlowski, K., Poirier, G.G., Smith, S., Timinszky, G., Wang, Z.Q., Yélamos, J., Yu, X.C., Zaja, R., and Ziegler, M. (2022). ADP-ribosyltransferases, an update on function and nomenclature. Febs Journal289, 7399-7410. 10.1111/febs.16142.
• Pouikli, A., Maleszewska, M., Parekh, S., Yang, M., Nikopoulou, C., Bonfiglio, J.J., Mylonas, C., Sandoval, T., Schumacher, A.L., Hinze, Y., Matic, I., Frezza, C., and Tessarz, P. (2022). Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication. EMBO J41, e111239. 10.15252/embj.2022111239.

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Elisa Motori

• Wani, G.A., Sprenger, H.G., Ndoci, K., Chandragiri, S., Acton, R.J., Schatton, D., Kochan, S.M.V., Sakthivelu, V., Jevtic, M., Seeger, J.M., Muller, S., Giavalisco, P., Rugarli, E.I., Motori, E., Langer, T., and Bergami, M. (2022). Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L. Cell Rep38, 110370. 10.1016/j.celrep.2022.110370.
• Zhu, X.F., Xie, X., Das, H., Tan, B.G., Shi, Y.H., Al-Behadili, A., Peter, B., Motori, E., Valenzuela, S., Posse, V., Gustafsson, C.M., Hallberg, B.M., and Falkenberg, M. (2022). Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell185, 2309-+. 10.1016/j.cell.2022.05.006.

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Roman-Ulrich Müller

• Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T,Schermer B, Schwarz G, Burst V, Müller RU (2022). A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism. Transl Res. 2022 Feb 18:S1931-5244(22)00023-8. doi: 10.1016/j.trsl.2022.02.003. Epub ahead of print. PMID: 35189406. 
• Müller RU, Messchendorp AL, Birn H, Capasso G, Cornec-Le Gall E, Devuyst O, van Eerde A, Guirchoun P, Harris T, Hoorn EJ, Knoers NVAM, Korst U, Mekahli D, Le Meur Y, Nijenhuis T, Ong ACM, Sayer JA, Schaefer F, Servais A, Tesar V, Torra R, Walsh SB, Gansevoort RT (2022). An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International. Nephrol Dial Transplant. 2022 Apr 25;37(5):825-839. doi: 10.1093/ndt/gfab312. PMID: 35134221; PMCID: PMC9035348. 
• Koehler FC, Späth MR, Hoyer-Allo KJR, Müller RU (2022). Mechanisms of Caloric Restriction-Mediated Stress-Resistance in Acute Kidney Injury.Nephron. 2022;146(3):234-238. doi: 10.1159/000517733. Epub 2021 Aug 2. PMID: 34340234; PMCID: PMC9216310.
• Aapkes, S.E., Bernts L.H.P., van den Berg A.P., van den Berg M, Blokzijl H, Cantineau A.E.P., van Gastel M.D.A., de Haas R.J., Kappert P, Müller R.U., Nevens F., Torra R., Visser A., Drenth J.P.H., Gansevoort R.T. (2022). Protocol for a randomized controlled multicenter trial assessing the efficacy of leuprorelin for severe polycystic liver disease: the AGAINST-PLD study. BMC Gastroenterol. 22, 82. doi.org/10.1186/s12876-022-02142-y
• Hoyer-Allo K.J.R, Späth M.R, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Broenneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler F.C, Grundmann F, Hackl M.J, Schermer B, Brüning J, Benzing T, Burst V. and Müller R.-U (2022). Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney International 0. https://doi.org/10.1016/j.kint.2022.04.033
• Osterholt T, Gloistein C, Todorova P, Becker I, Arenskrieger K, Melka R, Koehler F.C, Faust M, Wahlers T, Benzing T, Müller R.-U, Grundmann F, Burst (2022). Preoperative Short‐Term Restriction of Sulfur‐Containing Amino Acid Intake for Prevention of Acute Kidney Injury After Cardiac Surgery: A Randomized, Controlled, Double‐Blind, Translational Trial. Journal of the American Heart Association. 0, e025229. https://doi.org/10.1161/JAHA.121.025229
• Affeldt, P., Koehler, F.C., Brensing, K.A., Gies, M., Platen, E., Adam, V., Butt, L., Grundmann, F., Heger, E., Hinrichs, S., Kalisch, N., Oehm, S., Steger, G., Wirtz, M., Benzing, T., Stippel, D., Klein, F., Kurschat, C., Muller, R.U., and Di Cristanziano, V. (2022). Immune Response to Third and Fourth COVID-19 Vaccination in Hemodialysis Patients and Kidney Transplant Recipients. Viruses14. 10.3390/v14122646.
• Karner, L.A., Arjune, S., Todorova, P., Maintz, D., Grundmann, F., Persigehl, T., and Muller, R.U. (2022). Cyst Fraction as a Biomarker in Autosomal Dominant Polycystic Kidney Disease. J Clin Med12. 10.3390/jcm12010326.
• Koehler, F.C., Di Cristanziano, V., Spath, M.R., Hoyer-Allo, K.J.R., Wanken, M., Muller, R.U., and Burst, V. (2022). The kidney in hantavirus infection-epidemiology, virology, pathophysiology, clinical presentation, diagnosis and management. Clin Kidney J15, 1231-1252. 10.1093/ckj/sfac008.
• Seufert, L., Benzing, T., Ignarski, M., and Muller, R.U. (2022). RNA-binding proteins and their role in kidney disease. Nat Rev Nephrol18, 153-170. 10.1038/s41581-021-00497-1.
• Strubl, S., Oehm, S., Torres, J.A., Grundmann, F., Haratani, J., Decker, M., Vuong, S., Kaur Bhandal, A., Methot, N., Haynie-Cion, R., Meyer, F., Siedek, F., Korst, U., Muller, R.U., and Weimbs, T. (2022). Ketogenic dietary interventions in autosomal dominant polycystic kidney disease-a retrospective case series study: first insights into feasibility, safety and effects. Clin Kidney J15, 1079-1092. 10.1093/ckj/sfab162.
• Unnersjo-Jess, D., Ramdedovic, A., Hohne, M., Butt, L., Koehler, F.C., Muller, R.U., Hoyer, P.F., Blom, H., Schermer, B., and Benzing, T. (2022). Three-Dimensional Super-Resolved Imaging of Paraffin-Embedded Kidney Samples. Kidney3603, 446-454. 10.34067/KID.0005882021.
• Woznicki, P., Siedek, F., van Gastel, M.D.A., Dos Santos, D.P., Arjune, S., Karner, L.A., Meyer, F., Caldeira, L.L., Persigehl, T., Gansevoort, R.T., Grundmann, F., Baessler, B., and Muller, R.U. (2022). Automated Kidney and Liver Segmentation in MR Images in Patients with Autosomal Dominant Polycystic Kidney Disease: A Multicenter Study. Kidney3603, 2048-2058. 10.34067/KID.0003192022.

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Carien Niessen

• Peskoller M, Bhosale A, Göbel K, Löhr J, Miceli S, Perot S, Persa O, Rübsam M, Shah J, Zhang H, Niessen CM (2022). How to Build and Regenerate a Functional Skin Barrier: The Adhesive and Cell Shaping Travels of a Keratinocyte. J Invest Dermatol. 2022 Jan 17:S0022-202X(22)00010-0. doi: 10.1016/j.jid.2021.12.034. Epub ahead of print. PMID: 35051379.
• Rietscher K, Jahnke HG, Rübsam M, Lin EW, Has C, Omary MB, Niessen CM, Magin TM (2022). Kinase Inhibition by PKC412 Prevents Epithelial Sheet Damage in Autosomal Dominant Epidermolysis Bullosa Simplex through Keratin and Cell Contact Stabilization. J Invest Dermatol. 2022 Jun 9:S0022-202X(22)01531-7. doi: 10.1016/j.jid.2022.05.1088. Epub ahead of print. PMID: 35691363. 
• Green KJ, Niessen CM, Rübsam M, Perez White BE, Broussard JA (2022). The Desmosome-Keratin Scaffold Integrates ErbB Family and Mechanical Signaling to Polarize Epidermal Structure and Function. Front Cell Dev Biol. 2022 May 24;10:903696. doi: 10.3389/fcell.2022.903696. PMID: 35686051; PMCID: PMC9171019.
• Koehler S, Odenthal J, Ludwig V, Unnersjö Jess D, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T, Iden S, Brinkkoetter PT (2022). Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int. Apr;101(4):733-751. doi: 10.1016/j.kint.2021.11.030. Epub 2021 Dec 17. PMID: 34929254.
• Rübsam, M., Püllen, R., Telkamp, F., Bianco, A., Pescoller, M., Bloch, W., Green, K.J., Merkel, R., Hoffmann, B., Wickström, S., and Niessen, C. (2022). aPKC is a rheostat that controls basal junctional dynamics and suprabasal cytoskeletal organization essential for epidermal dynamics and integrity. J Invest Dermatol142, S212-S212.

Maria Notara

• Domdey, M., Kluth, M.A., Masslo, C., Ganss, C., Frank, M.H., Frank, N.Y., Coroneo, M.T., Cursiefen, C., and Notara, M. (2022). Consecutive dosing of UVB irradiation induces loss of ABCB5 expression and activation of EMT and fibrosis proteins in limbal epithelial cells similar to pterygium epithelium. Stem Cell Res64, 102936. 10.1016/j.scr.2022.102936.
• Volatier, T., Kluth, A., Masslo, C., Ganss, C., Frank, M.H., Frank, N., Schumacher, B., Notara, M., and Cursiefen, C. (2022). UVB activates autophagy in corneal epithelial stem cells. Invest Ophth Vis Sci63.
• Volatier, T., Schumacher, B., Cursiefen, C., and Notara, M. (2022). UV Protection in the Cornea: Failure and Rescue. Biology (Basel)11. 10.3390/biology11020278.

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Linda Partridge

• Laskovs M., Partridge L & Slack C (2022). Molecular inhibition of RAS signalling to target ageing and age-related health. Dis Model Mech. 15(10):dmm049627. doi: 10.1242/dmm.049627. Epub 2022 Sep 16. PMID: 36111627 Free PMC article. Review.
• Srivastava A, Lu J, Gadalla D.S, Hendrich O, Grönke S. & Partridge L (2022). The Role of GCN2 Kinase in Mediating the Effects of Amino Acids on Longevity and Feeding Behaviour in Drosophila. Front Aging. 3, 94446, doi: 10.3389/fragi.2022.944466. eCollection 2022. PMID: 35821827
• Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.
• Fraser HC, Kuan V, Johnen R, Zwierzyna M, Hingorani AD, Beyer A, Partridge L (2022). Biological mechanisms of aging predict age-related disease co-occurrence in patients. Aging Cell. 2022 Apr;21(4):e13524. doi: 10.1111/acel.13524.
• Baghdadi M, Hinterding H.M, Partridge L & Deelen J (2022). From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing. Brief Funct Genomics. 21, 13-23. doi: 10.1093/bfgp/elab005. PMID: 3369079Epub 2022 Mar 8. PMID: 35259281; PMCID: PMC9009120.
• Juricic, P., Lu, Y.X., Leech, T., Drews, L.F., Paulitz, J., Lu, J., Nespital, T., Azami, S., Regan, J.C., Funk, E., Frohlich, J., Gronke, S., and Partridge, L. (2022). Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy. Nat Aging2, 824-836. 10.1038/s43587-022-00278-w.
• Regan, J.C., Lu, Y.X., Ureña, E., Meilenbrock, R.L., Catterson, J.H., Kissler, D., Fröhlich, J., Funk, E., and Partridge, L. (2022). Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin. Nature Aging2, 1145-+. 10.1038/s43587-022-00308-7.

Manolis Pasparakis  

• Kondylis V, Schneider F, Schorn F, Oikonomou N, Straub BK, Werner S, Rosenstiel P, Pasparakis M (2022). p62 Promotes Survival and Hepatocarcinogenesis in Mice with Liver-Specific NEMO Ablation. Cancers (Basel). 2022 May 15;14(10):2436. doi: 10.3390/cancers14102436. PMID: 35626041; PMCID: PMC9139637.
• Imai T, Van TM, Pasparakis M, Polykratis A (2022). Smooth muscle cell specific NEMO deficiency inhibits atherosclerosis in ApoE^-/- mice. Sci Rep. Jul 22;12(1):12538. doi: 10.1038/s41598-022-16737-8. PMID: 35869246; PMCID: PMC9307802.
• Jiao H, Pasparakis M (2022). Inducing Z-DNA overcomes immune checkpoint blockade resistance. Cell Res. Oct;32(10):871-872. doi: 10.1038/s41422-022-00705-y. PMID: 35915243; PMCID: PMC9525283.
• Jiao H, Wachsmuth L, Wolf S, Lohmann J, Nagata M, Kaya GG, Oikonomou N, Kondylis V, Rogg M, Diebold M, Tröder SE, Zevnik B, Prinz M, Schell C, Young GR, Kassiotis G, Pasparakis M (2022). ADAR1 averts fatal type I interferon induction by ZBP1. Nature. Jul;607(7920):776-783. doi: 10.1038/s41586-022-04878-9. PMID: 35859176; PMCID: PMC9329096.
• Kopelyanskiy D, Desponds C, Prevel F, Rossi M, Migliorini R, Snäkä T, Eren RO, Claudinot S, Lye LF, Pasparakis M, Beverley SM, Fasel N (2022). Leishmania guyanensis suppressed inducible nitric oxide synthase provoked by its viral endosymbiont. Front Cell Infect Microbiol. 2022 Aug 12;12:944819. doi: 10.3389/fcimb.2022.944819. PMID: 36034693; PMCID: PMC9416488.
• Hausmann, A., Felmy, B., Kunz, L., Kroon, S., Berthold, D.L., Ganz, G., Sandu, I., Nakamura, T., Zangger, N., Zhang, Y., Dolowschiak, T., Fattinger, S.A., Furter, M., Mueller, H.A.A., Barthel, M., Vlantis, K., Wachsmuth, L., Kisielow, J., Tortola, L., Heide, D., Heikenwaelder, M., Oxenius, A., Kopf, M., Schroeder, T., Pasparakis, M., Sellin, M.E., and Hardt, W.D. (2022). Intercrypt sentinel macrophages induce a tunable antibacterial NF kappa B response in intestinal epithelial cells via TNF. Eur J Immunol52, 120-120.
• Vesting, A.J., Jais, A., Klemm, P., Steuernagel, L., Wienand, P., Fog-Tonnesen, M., Hvid, H., Schumacher, A.L., Kukat, C., Nolte, H., Georgomanolis, T., Altmuller, J., Pasparakis, M., Schmidt, A., Kruger, M., Supprian, M.S., Waisman, A., Straub, B.K., Raschzok, N., Bernier, M., Birkenfeld, A.L., Hovelmeyer, N., Bruning, J.C., and Wunderlich, F.T. (2022). NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition. Mol Metab66, 101626. 10.1016/j.molmet.2022.101626.
• Wolf, S., Wachsmuth, L., Oikonomou, N., and Pasparakis, M. (2022). The role of inflammatory and cell death mechanisms in the Trex1(-/-) autoimmune model. Eur J Immunol52, 296-297.

M. de las Nieves Peltzer 

• Peltzer N (2022). Linear ubiquitin as a common regulator of cellular stress. FEBS J. 2022 Mar 16. doi: 10.1111/febs.16427. Epub ahead of print. PMID: 35293134.
• Peltzer N* and Annibaldi A* (2022). Cell Death-Related Ubiquitin Modifications in Inflammatory Syndromes: From Mice to Men. Biomedicines. doi:10.3390/biomedicines10061436 (*co-corresponding authors)

Lena Pernas

• Li X, Straub J, Medeiros TC, Mehra C, den Brave F, Peker E, Atanassov I, Stillger K, Michaelis JB, Burbridge E, Adrain C, Münch C, Riemer J, Becker T, Pernas LF (2022). Mitochondria shed their outer membrane in response to infection-induced stress. Science. 2022 Jan 14;375(6577):eabi4343. doi: 10.1126/science.abi4343. Epub 2022 Jan 14. PMID: 35025629.
• Pálfy, M., and Pernas, L. (2022). Cell scientist to watch - Lena Pernas. Journal of Cell Science135. ARTN jcs260704. 10.1242/jcs.260704.

Dominik Pesta

• Pesta D, Jordan J (2022). Macronutrient composition and metabolic regulation: Do our islets care what we eat? Acta Physiol (Oxf). 2022 Oct 10:e13895. doi: 10.1111/apha.13895.
• Frett T, Lecheler L, Speer M, Marcos D, Pesta D, Tegtbur U, Schmitz MT, Jordan J, Green DA (2022). Comparison of trunk muscle exercises in supine position during short arm centrifugation with 1 g at centre of mass and upright in 1 g. Front Physiol. 2022 Aug 17;13:955312. doi: 10.3389/fphys.2022.955312. eCollection 2022.
• Pafili K, Kahl S, Mastrototaro L, Strassburger K, Pesta D, Herder C, Pützer J, Dewidar B, Hendlinger M, Granata C, Saatmann N, Yavas A, Gancheva S, Heilmann G, Esposito I, Schlensak M, Roden M (2022). Mitochondrial respiration is decreased in visceral but not subcutaneous adipose tissue in obese individuals with fatty liver disease. J Hepatol. Aug 19:S0168-8278(22)03010-0. doi: 10.1016/j.jhep.2022.08.010. Epub ahead of print. PMID: 35988689.
• Jelenik T*, Kodde A*, Pesta D*, Phielix E, Oosting A, Rohbeck E, Dewidar B, Mastrototaro L, Trenkamp S, Keijer J, van der Beek EM, Roden M (2022). Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming. Pharmacol Res. 2022 May;179:106193. doi: 10.1016/j.phrs.2022.106193. Epub 2022 Mar 28.
• Pesta D, Jordan J (2022). INDY as a Therapeutic Target for Cardio-Metabolic Disease. Metabolites. 2022 Mar 14;12(3):244. doi: 10.3390/metabo12030244.

Boris Pfander

• Kunert, F., Metzner, F.J., Jung, J., Hopfler, M., Woike, S., Schall, K., Kostrewa, D., Moldt, M., Chen, J.X., Bantele, S., Pfander, B., Eustermann, S., and Hopfner, K.P. (2022). Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv8. ARTN eadd3189. 10.1126/sciadv.add3189.
• Reusswig, K.U., Bittmann, J., Peritore, M., Courtes, M., Pardo, B., Wierer, M., Mann, M., and Pfander, B. (2022). Unscheduled DNA replication in G1 causes genome instability and damage signatures indicative of replication collisions. Nat Commun13. ARTN 7014. 10.1038/s41467-022-34379-2.

Valentina Piano

• Zilio, E., Piano. V., and Wirth, B. (2022). Mitochondrial Dysfunction in Spinal Muscular Atrophy. International Journal of Molecular Sciences23. ARTN 10878. 10.3390/ijms231810878.

Christina Polidori

• Heeß A, Meyer AM, Becker I, Noetzel N, Verleysdonk J, Rarek M, Benzing T, Polidori MC (2021). The prognostic fingerprint of quality of life in older inpatients : Relationship to geriatric syndromes' and resources' profile. Z Gerontol Geriatr. 2022 Feb;55(1):38-43. English. doi: 10.1007/s00391-021-01978-5. Epub 2021 Oct 6. PMID: 34617144. 
• Meyer AM, Pickert L, Heeß A, Becker I, Kurschat C, Bartram MP, Benzing T, Polidori MC (2022). Prognostic Signature of Chronic Kidney Disease in Advanced Age: Secondary Analysis from the InGAH Study with One-Year Follow-Up. Biomolecules. 2022 Mar 9;12(3):423. doi: 10.3390/biom12030423. PMID: 35327615; PMCID: PMC8946591.
• Zampino M, Polidori MC, Ferrucci L, O'Neill D, Pilotto A, Gogol M, Rubenstein L (2022). Biomarkers of aging in real life: three questions on aging and the comprehensive geriatric assessment. Geroscience. Jul 7. doi: 10.1007/s11357-022-00613-4. PMID: 35796977.
• Lemhöfer C, Appel KS, Häuser W, Hettich N, Kohls M, Polidori MC (2022). Post COVID - Just amatter of definition? Dtsch Med Wochenschr. 2022 Oct;147(21):1391-1397. doi: 10.1055/a-1940-1222. Epub 2022 Oct 24.PMID: 36279865 
• Presta R, Brunetti E, Polidori MC, Bo M (2022). Impact of frailty models on the prescription of oral anticoagulants and on the incidence of stroke, bleeding, and mortality in older patients with atrial fibrillation: a systematic review. Ageing Res Rev. 2022 Oct 18;82:101761. doi: 10.1016/j.arr.2022.101761. Online ahead of print.PMID: 36270605 Review.
• Meyer AM, Bartram MP, Antczak P, Becker I, Benzing T, Polidori MC (2022). A Tailored Discharge Program Improves Frailty and Mood in Patients Undergoing Usual Rehabilitative Care: A Randomized Controlled Trial. J Am Med Dir Assoc. 2022 Oct 10:S1525-8610(22)00676-4. doi: 10.1016/j.jamda.2022.09.003. Online ahead of print.PMID: 36228662
• Pilotto A, Veronese N, Polidori MC, Strandberg T, Topinkova E, Cruz-Jentoft AJ, Custodero C, Maggi S; EUROSAF Study Investigators (2022). The role of prognostic stratification on prescription of anticoagulants in older patients with atrial fibrillation: a multicenter, observational, prospective European study (EUROSAF). Ann Med. 2022 Dec;54(1):2411-2419. doi: 10.1080/07853890.2022.2117407.PMID: 36062815 Free PMC article.
• Pilotto A, Topinkova E, Michalkova H, Polidori MC, Cella A, Cruz-Jentoft A, von Arnim CAF, Azzini M, Gruner H, Castagna A, Cenderello G, Custureri R, Custodero C, Zieschang T, Padovani A, Sanchez-Garcia E, Veronese N; MPI-COVID-19 Study Group Investigators (2022). Can the Multidimensional Prognostic Index Improve the Identification of Older Hospitalized Patients with COVID-19 Likely to Benefit from Mechanical Ventilation? An Observational, Prospective, Multicenter Study. J Am Med Dir Assoc. 2022 Sep;23(9):1608.e1-1608.e8. doi: 10.1016/j.jamda.2022.06.023. Epub 2022 Jul 1.PMID: 35934019 Free PMC article.
• Polidori MC, Mecocci P (2022). Modeling the dynamics of energy imbalance: The free radical theory of aging and frailty revisited. Free Radic Biol Med. 2022 Mar;181:235-240. doi: 10.1016/j.freeradbiomed.2022.02.009. Epub 2022 Feb 10.PMID: 35151828 Review.
• Polidori MC, Alves M, Bahat G, Boureau AS, Ozkok S, Pfister R, Pilotto A, Veronese N, Bo M; Special Interest Group “Cardiovascular Diseases” of the EuGMS (2022). Atrial fibrillation: a geriatric perspective on the 2020 ESC guidelines. Eur Geriatr Med. 2022 Feb;13(1):5-18. doi: 10.1007/s41999-021-00537-w. Epub 2021 Nov 2.PMID: 34727362 Free PMC article. Review.
• Lagolio, E., Demurtas, J., Buzzetti, R., Cortassa, G., Bottone, S., Spadafora, L., Cocino, C., Smith, L., Benzing, T., and Polidori, M.C. (2022). A rapid and feasible tool for clinical decision making in community-dwelling patients with COVID-19 and those admitted to emergency departments: the Braden-LDH-HorowITZ Assessment-BLITZ. Intern Emerg Med17, 839-844. 10.1007/s11739-021-02805-w.

Simon Pöpsel

• Winkler R, Mägdefrau AS, Piskor EM, Kleemann M, Beyer M, Linke K, Hansen L, Schaffer AM, Hoffmann ME, Pöpsel S, Heyd F, Beli P, Möröy T, Mahboobi S, Krämer OH, Kosan C (2022). Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition. Oncogene. 2022 Sep;41(40):4560-4572. doi: 10.1038/s41388-022-02450-3. Epub 2022 Sep 6. PMID: 36068335; PMCID: PMC9525236.
• Pavlenko, E., Ruengeler, T., Engel, P., Poepsel, S (2022). Functions and interactions of mammalian KDM5 demethylases. Frontiers in Genetics. 2022, 13:906662, doi: 10.3389/fgene.2022.906662.

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Alvaro Rada-Iglesias

• Srinivasan, S.P., Nemade, H., Cherianidou, A., Peng, L., Cruz-Molina, S., Rada-Iglesias, A., and Sachinidis, A. (2022). Epigenetic mechanisms of Strip2 in differentiation of pluripotent stem cells. Cell Death Discov8, 447. 10.1038/s41420-022-01237-5.
• Stussel, L.G., Hollstein, R., Laugsch, M., Hochfeld, L.M., Welzenbach, J., Schroder, J., Thieme, F., Ishorst, N., Romero, R.O., Weinhold, L., Hess, T., Gehlen, J., Mostowska, A., Heilmann-Heimbach, S., Mangold, E., Rada-Iglesias, A., Knapp, M., Schaaf, C.P., and Ludwig, K.U. (2022). MiRNA-149 as a Candidate for Facial Clefting and Neural Crest Cell Migration. Journal of Dental Research101, 323-330. Artn 00220345211038203. 10.1177/00220345211038203.
• Vicioso-Mantis, M., Fueyo, R., Navarro, C., Cruz-Molina, S., van Ijcken, W.F.J., Rebollo, E., Rada-Iglesias, A., and Martinez-Balbas, M.A. (2022). JMJD3 intrinsically disordered region links the 3D-genome structure to TGFbeta-dependent transcription activation. Nat Commun13, 3263. 10.1038/s41467-022-30614-y.

Alfredo Ramirez

• Lahti J, Tuominen S, Yang Q, Pergola G, Ahmad S, Amin N, Armstrong NJ, Beiser A, Bey K, Bis JC, Boerwinkle E, Bressler J, Campbell A, Campbell H, Chen Q, Corley J, Cox SR, Davies G, De Jager PL, Derks EM, Faul JD, Fitzpatrick AL, Fohner AE, Ford I, Fornage M, Gerring Z, Grabe HJ, Grodstein F, Gudnason V, Simonsick E, Holliday EG, Joshi PK, Kajantie E, Kaprio J, Karell P, Kleineidam L, Knol MJ, Kochan NA, Kwok JB, Leber M, Lam M, Lee T, Li S, Loukola A, Luck T, Marioni RE, Mather KA, Medland S, Mirza SS, Nalls MA, Nho K, O'Donnell A, Oldmeadow C, Painter J, Pattie A, Reppermund S, Risacher SL, Rose RJ, Sadashivaiah V, Scholz M, Satizabal CL, Schofield PW, Schraut KE, Scott RJ, Simino J, Smith AV, Smith JA, Stott DJ, Surakka I, Teumer A, Thalamuthu A, Trompet S, Turner ST, van der Lee SJ, Villringer A, Völker U, Wilson RS, Wittfeld K, Vuoksimaa E, Xia R, Yaffe K, Yu L, Zare H, Zhao W, Ames D, Attia J, Bennett DA, Brodaty H, Chasman DI, Goldman AL, Hayward C, Ikram MA, Jukema JW, Kardia SLR, Lencz T, Loeffler M, Mattay VS, Palotie A, Psaty BM, Ramirez A, Ridker PM, Riedel-Heller SG, Sachdev PS, Saykin AJ, Scherer M, Schofield PR, Sidney S, Starr JM, Trollor J, Ulrich W, Wagner M, Weir DR, Wilson JF, Wright MJ, Weinberger DR, Debette S, Eriksson JG, Mosley TH Jr, Launer LJ, van Duijn CM, Deary IJ, Seshadri S, Räikkönen K (2022). Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning. Mol Psychiatry. 2022 Aug 16. doi: 10.1038/s41380-022-01710-8. Online ahead of print. PMID: 35974141
• Dumont M, Weber-Lassalle N, Joly-Beauparlant C, Ernst C, Droit A, Feng BJ, Dubois S, Collin-Deschesnes AC, Soucy P, Vallée M, Fournier F, Lemaçon A, Adank MA, Allen J, Altmüller J, Arnold N, Ausems MGEM, Berutti R, Bolla MK, Bull S, Carvalho S, Cornelissen S, Dufault MR, Dunning AM, Engel C, Gehrig A, Geurts-Giele WRR, Gieger C, Green J, Hackmann K, Helmy M, Hentschel J, Hogervorst FBL, Hollestelle A, Hooning MJ, Horváth J, Ikram MA, Kaulfuß S, Keeman R, Kuang D, Luccarini C, Maier W, Martens JWM, Niederacher D, Nürnberg P, Ott CE, Peters A, Pharoah PDP, Ramirez A, Ramser J, Riedel-Heller S, Schmidt G, Shah M, Scherer M, Stäbler A, Strom TM, Sutter C, Thiele H, van Asperen CJ, van der Kolk L, van der Luijt RB, Volk AE, Wagner M, Waisfisz Q, Wang Q, Wang-Gohrke S, Weber BHF, Genome Of The Netherlands Project, Ghs Study Group, Devilee P, Tavtigian S, Bader GD, Meindl A, Goldgar DE, Andrulis IL, Schmutzler RK, Easton DF, Schmidt MK, Hahnen E, Simard J (2022). Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry. Cancers (Basel). 2022 Jul 11;14(14):3363. doi: 10.3390/cancers14143363. PMID: 35884425
• Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, Ortiz AB, Salazar A, Chercoles AG, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A, Holten AR, Mayer A, Bandera A, Cherubini A, Protti A, Aghemo A, Gerussi A, Ramirez A, Braun A, Nebel A, Barreira A, Lleo A, Teles A, Kildal AB, Biondi A, Caballero-Garralda A, Ganna A, Gori A, Glück A, Lind A, Tanck A, Hinney A, Nolla AC, Fracanzani AL, Peschuck A, Cavallero A, Dyrhol-Riise AM, Ruello A, Julià A, Muscatello A, Pesenti A, Voza A, Rando-Segura A, Solier A, Schmidt A, Cortes B, Mateos B, Nafria-Jimenez B, Schaefer B, Jensen B, Bellinghausen C, Maj C, Ferrando C, Horra C, Quereda C, Skurk C, Thibeault C, Scollo C, Herr C, Spinner CD, Gassner C, Lange C, Hu C, Paccapelo C, Lehmann C, Angelini C, Cappadona C, Azuure C; COVICAT study group, Aachen Study (COVAS), Bianco C, Cea C, Sancho C, Hoff DAL, Galimberti D, Prati D, Haschka D, Jiménez D, Pestaña D, Toapanta D, Muñiz-Diaz E, Azzolini E, Sandoval E, Binatti E, Scarpini E, Helbig ET, Casalone E, Urrechaga E, Paraboschi EM, Pontali E, Reverter E, Calderón EJ, Navas E, Solligård E, Contro E, Arana-Arri E, Aziz F, Garcia F, Sánchez FG, Ceriotti F, Martinelli-Boneschi F, Peyvandi F, Kurth F, Blasi F, Malvestiti F, Medrano FJ, Mesonero F, Rodriguez-Frias F, Hanses F, Müller F, Hemmrich-Stanisak G, Bellani G, Grasselli G, Pezzoli G, Costantino G, Albano G, Cardamone G, Bellelli G, Citerio G, Foti G, Lamorte G, Matullo G, Baselli G, Kurihara H, Neb H, My I, Kurth I, Hernández I, Pink I, Rojas I, Galván-Femenia I, Holter JC, Afset JE, Heyckendorf J, Kässens J, Damås JK, Rybniker J, Altmüller J, Ampuero J, Martín J, Erdmann J, Banales JM, Badia JR, Dopazo J, Schneider J, Bergan J, Barretina J, Walter J, Quero JH, Goikoetxea J, Delgado J, Guerrero JM, Fazaal J, Kraft J, Schröder J, Risnes K, Banasik K, Müller KE, Gaede KI, Garcia-Etxebarria K, Tonby K, Heggelund L, Izquierdo-Sanchez L, Bettini LR, Sumoy L, Sander LE, Lippert LJ, Terranova L, Nkambule L, Knopp L, Gustad LT, Garbarino L, Santoro L, Téllez L, Roade L, Ostadreza M, Intxausti M, Kogevinas M, Riveiro-Barciela M, Berger MM, Schaefer M, Niemi MEK, Gutiérrez-Stampa MA, Carrabba M, Figuera Basso ME, Valsecchi MG, Hernandez-Tejero M, Vehreschild MJGT, Manunta M, Acosta-Herrera M, D'Angiò M, Baldini M, Cazzaniga M, Grimsrud MM, Cornberg M, Nöthen MM, Marquié M, Castoldi M, Cordioli M, Cecconi M, D'Amato M, Augustin M, Tomasi M, Boada M, Dreher M, Seilmaier MJ, Joannidis M, Wittig M, Mazzocco M, Ciccarelli M, Rodríguez-Gandía M, Bocciolone M, Miozzo M, Ayo NI, Blay N, Chueca N, Montano N, Braun N, Ludwig N, Marx N, Martínez N; Norwegian SARS-CoV-2 Study group, Cornely OA, Witzke O, Palmieri O; Pa Study Group, Faverio P, Preatoni P, Bonfanti P, Omodei P, Tentorio P, Castro P, Rodrigues PM, España PP, Hoffmann P, Rosenstiel P, Schommers P, Suwalski P, Pablo R, Ferrer R, Bals R, Gualtierotti R, Gallego-Durán R, Nieto R, Carpani R, Morilla R, Badalamenti S, Haider S, Ciesek S, May S, Bombace S, Marsal S, Pigazzini S, Klein S, Pelusi S, Wilfling S, Bosari S, Volland S, Brunak S, Raychaudhuri S, Schreiber S, Heilmann-Heimbach S, Aliberti S, Ripke S, Dudman S, Wesse T, Zheng T; STORM Study group, The Humanitas Task Force, The Humanitas Gavazzeni Task Force, Bahmer T, Eggermann T, Illig T, Brenner T, Pumarola T, Feldt T, Folseraas T, Cejudo TG, Landmesser U, Protzer U, Hehr U, Rimoldi V, Monzani V, Skogen V, Keitel V, Kopfnagel V, Friaza V, Andrade V, Moreno V, Albrecht W, Peter W, Poller W, Farre X, Yi X, Wang X, Khodamoradi Y, Karadeniz Z, Latiano A, Goerg S, Bacher P, Koehler P, Tran F, Zoller H, Schulte EC, Heidecker B, Ludwig KU, Fernández J, Romero-Gómez M, Albillos A, Invernizzi P, Buti M, Duga S, Bujanda L, Hov JR, Lenz TL, Asselta R, Cid R, Valenti L, Karlsen TH, Cáceres M, Franke A (2022). Detailed stratified GWAS analysis for severe COVID-19 in four European populations. Hum Mol Genet. 2022 Jul 15:ddac158. doi: 10.1093/hmg/ddac158. Online ahead of print. PMID: 35848942
• Jessen F, Wolfsgruber S, Kleineindam L, Spottke A, Altenstein S, Bartels C, Berger M, Brosseron F, Daamen M, Dichgans M, Dobisch L, Ewers M, Fenski F, Fliessbach K, Freiesleben SD, Glanz W, Görß D, Gürsel S, Janowitz D, Kilimann I, Kobeleva X, Lohse A, Maier F, Metzger C, Munk M, Preis L, Sanzenbacher C, Spruth E, Rauchmann B, Vukovich R, Yakupov R, Weyrauch AS, Ziegler G, Schmid M, Laske C, Perneczky R, Schneider A, Wiltfang J, Teipel S, Bürger K, Priller J, Peters O, Ramirez A, Boecker H, Heneka MT, Wagner M, Düzel E (2022). Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers. Alzheimers Dement. 2022 Apr 22. doi: 10.1002/alz.12674. Online ahead of print. PMID: 35451563
• Düzel E, Ziegler G, Berron D, Maass A, Schütze H, Cardenas-Blanco A, Glanz W, Metzger C, Dobisch L, Reuter M, Spottke A, Brosseron F, Fliessbach K, Heneka MT, Laske C, Peters O, Priller J, Spruth EJ, Ramirez A, Speck O, Schneider A, Teipel S, Kilimann I, Jens W, Schott BH, Preis L, Gref D, Maier F, Munk MH, Roy N, Ballarini T, Yakupov R, Haynes JD, Dechent P, Scheffler K, Wagner M, Jessen F (2022). Amyloid pathology but not APOE ε4 status is permissive for tau-related hippocampal dysfunction. Brain. 2022 May 24;145(4):1473-1485. doi: 10.1093/brain/awab405. PMID: 35352105
• Mourtzi N, Hatzimanolis A, Xiromerisiou G, Ntanasi E, Georgakis MK, Ramirez A, Heilmann-Heimbach S, Grenier-Boley B, Lambert JC, Yannakoulia M, Kosmidis M, Dardiotis E, Hadjigeorgiou G, Sakka P, Scarmeas N (2022). Association between 9p21-23 Locus and Frailty in a Community-Dwelling Greek Population: Results from the Hellenic Longitudinal Investigation of Ageing and Diet. J Prev Alzheimers Dis. 2022;9(1):77-85. doi: 10.14283/jpad.2022.2. PMID: 35098976
• Maraki MI, Hatzimanolis A, Mourtzi N, Stefanis L, Yannakoulia M, Kosmidis MH, Dardiotis E, Hadjigeorgiou GM, Sakka P, Ramirez A, Grenier-Boley B, Lambert JC, Heilmann-Heimbach S, Stamelou M, Scarmeas N, Xiromerisiou G (2022). Association of the Polygenic Risk Score With the Probability of Prodromal Parkinson's Disease in Older Adults. Front Mol Neurosci. 2021 Dec 21;14:739571. doi: 10.3389/fnmol.2021.739571. eCollection 2021. PMID: 34992521
• Martino Adami PV, Orellana A, García P, Kleineidam L, Alarcón-Martín E, Montrreal L, Aguilera N, Espinosa A, Abdelnour C, Rosende-Roca M, Tartari JP, Vargas L, Mauleón A, Esteban-De Antonio E, López-Cuevas R, Dalmasso MC, Martin RC, Parveen K, Andrade Fuentes VM, Amin N, Ahmad S, Ikram MA, Lewczuk P, Kornhuber J, Peters O, Frölich L, Rüther E, Wiltfang J, Tarraga L, Boada M, Maier W, de Rojas I, Cano A, Sanabria A, Alegret M, Hernández I, Marquié M, Valero S, van Duijn CM, Wagner M, Jessen F, Schneider A, Sáez Goñi ME, Pérez AG, Ruiz A, Ramírez A (2022). Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer's type. Brain. 2022 Jan 28:awac024. doi: 10.1093/brain/awac024. Epub ahead of print. PMID: 35088840.
• Belloy ME, Eger SJ, Le Guen Y, Damotte V, Ahmad S, Ikram MA, Ramirez A, Tsolaki AC, Rossi G, Jansen IE, de Rojas I, Parveen K, Sleegers K, Ingelsson M, Hiltunen M, Amin N, Andreassen O, Sánchez-Juan P, Kehoe P, Amouyel P, Sims R, Frikke-Schmidt R, van der Flier WM, Lambert JC; European Alzheimer & Dementia BioBank (EADB), He Z, Han SS, Napolioni V, Greicius MD (2022). Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping. Alzheimers Res Ther. 2022 Feb 4;14(1):22. doi: 10.1186/s13195-022-00962-4. PMID: 35120553; PMCID: PMC8815198.
• Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, Düzel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, Laske C, Maier F, Metzger CD, Munk MH, Peters O, Pomara N, Preis L, Priller J, Ramírez A, Roy N, Scheffler K, Schneider A, Schott BH, Spottke A, Spruth EJ, Wagner M, Wiltfang J, Jessen F, Heneka MT. Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. J Alzheimers Dis. 2022;85(3):1267-1282. doi: 10.3233/JAD-215196. PMID: 34924387.
• Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W Jr, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, Tosto G, Traykov L, Tremolizzo L, Tybjærg-Hansen A, Uitterlinden A, Ullgren A, Ulstein I, Valero S, Valladares O, Broeckhoven CV, Vance J, Vardarajan BN, van der Lugt A, Dongen JV, van Rooij J, van Swieten J, Vandenberghe R, Verhey F, Vidal JS, Vogelgsang J, Vyhnalek M, Wagner M, Wallon D, Wang LS, Wang R, Weinhold L, Wiltfang J, Windle G, Woods B, Yannakoulia M, Zare H, Zhao Y, Zhang X, Zhu C, Zulaica M; EADB; GR@ACE; DEGESCO; EADI; GERAD; Demgene; FinnGen; ADGC; CHARGE, Farrer LA, Psaty BM, Ghanbari M, Raj T, Sachdev P, Mather K, Jessen F, Ikram MA, de Mendonça A, Hort J, Tsolaki M, Pericak-Vance MA, Amouyel P, Williams J, Frikke-Schmidt R, Clarimon J, Deleuze JF, Rossi G, Seshadri S, Andreassen OA, Ingelsson M, Hiltunen M, Sleegers K, Schellenberg GD, van Duijn CM, Sims R, van der Flier WM, Ruiz A, Ramirez A, Lambert JC (2022). New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet.2022 Apr;54(4):412-436. doi: 10.1038/s41588-022-01024-z. Epub 2022 Apr 4. PMID: 35379992; PMCID: PMC9005347. 
• Gerards M, Schild AK, Meiberth D, Rostamzadeh A, Vehreschild JJ, Wingen-Heimann S, Johannis W, Martino Adami P, Onur OA, Ramirez A, Karikari TK, Ashton NJ, Zetterberg H, Blennow K, Maier F, Jessen F(2022). Alzheimer's Disease Plasma Biomarkers Distinguish Clinical Diagnostic Groups in Memory Clinic Patients. Dement Geriatr Cogn Disord. 2022 May 3:1-11. doi: 10.1159/000524390. Epub ahead of print. PMID: 35504263.
• Wolfsgruber S, Kleineidam L, Weyrauch AS, Barkhoff M, Röske S, Peters O, Preis L, Gref D, Spruth EJ, Altenstein S, Priller J, Fließbach K, Schneider A, Wiltfang J, Bartels C, Jessen F, Maier F, Düzel E, Metzger C, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Kilimann I, Teipel S, Laske C, Munk MH, Roy N, Spottke A, Ramirez A, Heneka MT, Brosseron F, Wagner M; DELCODE study group (2022). Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease. J Alzheimers Dis. 2022;87(2):545-555. doi: 10.3233/JAD-215416. PMID: 35275535. 
• Le Guen Y, Belloy ME, Grenier-Boley B, de Rojas I, Castillo-Morales A, Jansen I, Nicolas A, Bellenguez C, Dalmasso C, Küçükali F, Eger SJ, Rasmussen KL, Thomassen JQ, Deleuze JF, He Z, Napolioni V, Amouyel P, Jessen F, Kehoe PG, van Duijn C, Tsolaki M, Sánchez-Juan P, Sleegers K, Ingelsson M, Rossi G, Hiltunen M, Sims R, van der Flier WM, Ramirez A, Andreassen OA, Frikke-Schmidt R, Williams J, Ruiz A, Lambert JC, Greicius MD; Members of the EADB, GR@ACE, DEGESCO, DemGene, GERAD, and EADI Groups, Arosio B, Benussi L, Boland A, Borroni B, Caffarra P, Daian D, Daniele A, Debette S, Dufouil C, Düzel E, Galimberti D, Giedraitis V, Grimmer T, Graff C, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Holstege H, Hort J, Jürgen D, Kuulasmaa T, van der Lugt A, Masullo C, Mecocci P, Mehrabian S, de Mendonça A, Moebus S, Nacmias B, Nicolas G, Olaso R, Papenberg G, Parnetti L, Pasquier F, Peters O, Pijnenburg YAL, Popp J, Rainero I, Ramakers I, Riedel-Heller S, Scarmeas N, Scheltens P, Scherbaum N, Schneider A, Seripa D, Soininen H, Solfrizzi V, Spalletta G, Squassina A, van Swieten J, Tegos TJ, Tremolizzo L, Verhey F, Vyhnalek M, Wiltfang J, Boada M, García-González P, Puerta R, Real LM, Álvarez V, Bullido MJ, Clarimon J, García-Alberca JM, Mir P, Moreno F, Pastor P, Piñol-Ripoll G, Molina-Porcel L, Pérez-Tur J, Rodríguez-Rodríguez E, Royo JL, Sánchez-Valle R, Dichgans M, Rujescu D (2022). Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease. JAMA Neurol. 2022 Jul 1;79(7):652-663. doi: 10.1001/jamaneurol.2022.1166. PMID: 35639372; PMCID: PMC9157381
• Billette OV, Ziegler G, Aruci M, Schütze H, Kizilirmak JM, Richter A, Altenstein S, Bartels C, Brosseron F, Cardenas-Blanco A, Dahmen P, Dechent P, Dobisch L, Fliessbach K, Freiesleben SD, Glanz W, Göerß D, Haynes JD, Heneka MT, Kilimann I, Kimmich O, Kleineidam L, Laske C, Lohse A, Rostamzadeh A, Metzger C, Munk MH, Peters O, Preis L, Priller J, Scheffler K, Schneider A, Spottke A, Spruth EJ, Ramirez A, Röske S, Roy N, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Yakupov R, Zeidman P, Jessen F, Schott BH, Düzel E, Maass A; DELCODE Study Group (2022). Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease. Neurology. Aug 23;99(8):e775-e788. doi: 10.1212/WNL.0000000000200667. Epub Jun 3. PMID: 35995589; PMCID: PMC9484732.
• Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, Vromen EM, Wightman DP, Alcolea D, Alegret M, Alvarez I, Amouyel P, Athanasiu L, Bahrami S, Bailly H, Belbin O, Bergh S, Bertram L, Biessels GJ, Blennow K, Blesa R, Boada M, Boland A, Buerger K, Carracedo Á, Cervera-Carles L, Chene G, Claassen JAHR, Debette S, Deleuze JF, de Deyn PP, Diehl-Schmid J, Djurovic S, Dols-Icardo O, Dufouil C, Duron E, Düzel E; EADB consortium, Fladby T, Fortea J, Frölich L, García-González P, Garcia-Martinez M, Giegling I, Goldhardt O, Gobom J, Grimmer T, Haapasalo A, Hampel H, Hanon O, Hausner L, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herukka SK, Holstege H, Jarholm J, Kern S, Knapskog AB, Koivisto AM, Kornhuber J, Kuulasmaa T, Lage C, Laske C, Leinonen V, Lewczuk P, Lleó A, de Munain AL, Lopez-Garcia S, Maier W, Marquié M, Mol MO, Montrreal L, Moreno F, Moreno-Grau S, Nicolas G, Nöthen MM, Orellana A, Pålhaugen L, Papma JM, Pasquier F, Perneczky R, Peters O, Pijnenburg YAL, Popp J, Posthuma D, Pozueta A, Priller J, Puerta R, Quintela I, Ramakers I, Rodriguez-Rodriguez E, Rujescu D, Saltvedt I, Sanchez-Juan P, Scheltens P, Scherbaum N, Schmid M, Schneider A, Selbæk G, Selnes P, Shadrin A, Skoog I, Soininen H, Tárraga L, Teipel S; GR@ACE study group, Tijms B, Tsolaki M, Van Broeckhoven C, Van Dongen J, van Swieten JC, Vandenberghe R, Vidal JS, Visser PJ, Vogelgsang J, Waern M, Wagner M, Wiltfang J, Wittens MMJ, Zetterberg H, Zulaica M, van Duijn CM, Bjerke M, Engelborghs S, Jessen F, Teunissen CE, Pastor P, Hiltunen M, Ingelsson M, Andreassen OA, Clarimón J, Sleegers K, Ruiz A, Ramirez A, Cruchaga C, Lambert JC, van der Flier W (2022). Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathol. 2022 Nov;144(5):821-842. doi: 10.1007/s00401-022-02454-z. Epub 2022 Sep 6. PMID: 36066633; PMCID: PMC9547780.
• Bey, K., Campos-Martin, R., Klawohn, J., Reuter, B., Grützmann, R., Riesel, A., Wagner, M., Ramirez, A., and Kathmann, N. (2022). Hypermethylation of the oxytocin receptor gene (OXTR) in obsessive-compulsive disorder: further evidence for a biomarker of disease and treatment response. Epigenetics-Us17, 642-652. 10.1080/15592294.2021.1943864.
• Brosseron, F., Maass, A., Kleineidam, L., Ravichandran, K.A., Gonzalez, P.G., McManus, R.M., Ising, C., Santarelli, F., Kolbe, C.C., Hasler, L.M., Wolfsgruber, S., Marquie, M., Boada, M., Orellana, A., de Rojas, I., Roske, S., Peters, O., Cosma, N.C., Cetindag, A., Wang, X., Priller, J., Spruth, E.J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Schott, B.H., Burger, K., Janowitz, D., Dichgans, M., Perneczky, R., Rauchmann, B.S., Teipel, S., Kilimann, I., Goerss, D., Laske, C., Munk, M.H., Duzel, E., Yakupov, R., Dobisch, L., Metzger, C.D., Glanz, W., Ewers, M., Dechent, P., Haynes, J.D., Scheffler, K., Roy, N., Rostamzadeh, A., Teunissen, C.E., Marchant, N.L., Spottke, A., Jucker, M., Latz, E., Wagner, M., Mengel, D., Synofzik, M., Jessen, F., Ramirez, A., Ruiz, A., Heneka, M.T., and group, D.s. (2022). Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron110, 1009-1022 e1004. 10.1016/j.neuron.2021.12.016.
• Dalmasso, M.C., Aran, M., Galeano, P., Perin, S., Giavalisco, P., Martino Adami, P.V., Novack, G.V., Castano, E.M., Cuello, A.C., Scherer, M., Maier, W., Wagner, M., Riedel-Heller, S., Ramirez, A., and Morelli, L. (2022). Nicotinamide as potential biomarker for Alzheimer's disease: A translational study based on metabolomics. Front Mol Biosci9, 1067296. 10.3389/fmolb.2022.1067296.
• Georgakis, M.K., Ntanasi, E., Ramirez, A., Grenier-Boley, B., Lambert, J.C., Sakka, P., Yannakoulia, M., Kosmidis, M.H., Dardiotis, E., Hadjigeorgiou, G.M., Charissis, S., Mourtzi, N., Hatzimanolis, A., and Scarmeas, N. (2022). Vascular burden and genetic risk in association with cognitive performance and dementia in a population-based study. Cereb Circ Cogn Behav3, 100145. 10.1016/j.cccb.2022.100145.
• Juarez-Cedillo, T., Martinez-Rodriguez, N., Vargas-Alarcon, G., Juarez-Cedillo, E., Valle-Medina, A., Garrido-Acosta, O., and Ramirez, A. (2022). Synergistic influence of cytokine gene polymorphisms over the risk of dementia: A multifactor dimensionality reduction analysis. Front Aging Neurosci14, 952173. 10.3389/fnagi.2022.952173.
• Kleineidam, L., Wolfsgruber, S., Weyrauch, A.S., Zulka, L.E., Forstmeier, S., Roeske, S., van den Bussche, H., Kaduszkiewicz, H., Wiese, B., Weyerer, S., Werle, J., Fuchs, A., Pentzek, M., Brettschneider, C., Konig, H.H., Weeg, D., Bickel, H., Luppa, M., Rodriguez, F.S., Freiesleben, S.D., Erdogan, S., Unterfeld, C., Peters, O., Spruth, E.J., Altenstein, S., Lohse, A., Priller, J., Fliessbach, K., Kobeleva, X., Schneider, A., Bartels, C., Schott, B.H., Wiltfang, J., Maier, F., Glanz, W., Incesoy, E.I., Butryn, M., Duzel, E., Buerger, K., Janowitz, D., Ewers, M., Rauchmann, B.S., Perneczky, R., Kilimann, I., Gorss, D., Teipel, S., Laske, C., Munk, M.H.J., Spottke, A., Roy, N., Brosseron, F., Heneka, M.T., Ramirez, A., Yakupov, R., Scherer, M., Maier, W., Jessen, F., Riedel-Heller, S.G., and Wagner, M. (2022). Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve. Front Psychol13, 957308. 10.3389/fpsyg.2022.957308.
• Melo van Lent, D., Egert, S., Wolfsgruber, S., Kleineidam, L., Weinhold, L., Wagner-Thelen, H., Stoffel-Wagner, B., Bickel, H., Wiese, B., Weyerer, S., Pentzek, M., Jessen, F., Schmid, M., Maier, W., Scherer, M., Riedel-Heller, S.G., Ramirez, A., and Wagner, M. (2022). Low Serum Vitamin D Status Is Associated with Incident Alzheimer's Dementia in the Oldest Old. Nutrients15. 10.3390/nu15010061.

Jane Reznick

• Buffenstein, R., Amoroso, V., Andziak, B., Avdieiev, S., Azpurua, J., Barker, A.J., Bennett, N.C., Brieño-Enríquez, M.A., Bronner, G.N., Coen, C., Delaney, M.A., Dengler-Crish, C.M., Edrey, Y.H., Faulkes, C.G., Frankel, D., Friedlander, G., Gibney, P.A., Gorbunova, V., Hine, C., Holmes, M.M., Jarvis, J.U.M., Kawamura, Y., Kutsukake, N., Kenyon, C., Khaled, W.T., Kikusui, T., Kissil, J., Lagestee, S., Larson, J., Lauer, A., Lavrenchenko, L.A., Lee, A., Levitt, J.B., Lewin, G.R., Hardell, K.N.L., Lin, Z.H., Mason, M.J., McCloskey, D., McMahon, M., Miura, K., Mogi, K., Narayan, V., O'Connor, T.P., Okanoya, K., O'Riain, M.J., Park, T.J., Place, N.J., Podshivalova, K., Pamenter, M.E., Pyott, S.J., Reznick, J., Ruby, J.G., Salmon, A.B., Santos-Sacchi, J., Sarko, D.K., Seluanov, A., Shepard, A., Smith, M., Storey, K.B., Tian, X., Vice, E.N., Viltard, M., Watarai, A., Wywial, E., Yamakawa, M., Zemlemerova, E.D., Zions, M., and Smith, E.S. (2022). The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology. Biol Rev97, 115-140. 10.1111/brv.12791.
• Park TJ, Reznick J (2022). Journal of muscle research and cell motility, focus on Extreme Physiology Extreme Tolerance to Hypoxia, Hypercapnia, and Pain in the Naked Mole-Rat. J Muscle Res Cell Motil. Jul 19. doi: 10.1007/s10974-022-09623-3. Epub ahead of print. PMID: 35854159.

Jan Riemer

• Li X, Straub J, Medeiros TC, Mehra C, den Brave F, Peker E, Atanassov I, Stillger K, Michaelis JB, Burbridge E, Adrain C, Münch C, Riemer J, Becker T, Pernas LF(2022). Mitochondria shed their outer membrane in response to infection-induced stress. Science. 2022 Jan 14;375(6577):eabi4343. doi: 10.1126/science.abi4343. Epub 2022 Jan 14. PMID: 35025629.
• Bolgi O, Silva-Garcia M, Ross B, Pilla E, Kari V, Killisch M, Spitzner M, Stark N, Lenz C, Weiss K, Donzelli L, Gorrell MD, Grade M, Riemer J, Urlaub H, Dobbelstein M, Huber R, Geiss-Friedlander R (2022). Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair. EMBO Rep. Oct 6;23(10):e54136. doi: 10.15252/embr.202154136. Epub Aug 1. PMID: 35912982; PMCID: PMC9535758.
• Jacobs LJHC, Riemer J (2022). Maintenance of small molecule redox homeostasis in mitochondria. FEBS Lett. 2022 Aug 27. doi: 10.1002/1873-3468.14485. Epub ahead of print. PMID: 36030088.
• Jacobs LJ, Hoehne MN, Riemer J (2022). Measuring Intracellular H2O2 in Intact Human Cells Using the Genetically Encoded Fluorescent Sensor HyPer7. Bio-protocol 12 
• Salscheider SL*, Gerlich S*, Cabrera-Orefice A*, Peker E, Rothemann RA, Murschall LM, Finger Y, Szczepanowska K, Ahmadi ZA, Guerrero-Castillo S, Erdogan A, Becker M, Ali M, Habich M, Petrungaro C, Burdina N, Schwarz G, Klußmann M, Neundorf I, Stroud DA, Ryan MT, Trifunovic A, Brandt U, Riemer J (2022). AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5. EMBO J. e110784.
• Weiss K, Racho J, Riemer J (2022). Compartmentalized disulfide bond formation pathways. Redox Chemistry and Biology of Thiols, 321-340.
• Hoehne MN, Jacobs LJHC, Lapacz KJ, Calabrese G, Murschall LM, Marker T, Kaul H, Trifunovic A, Morgan B, Fricker M, Belousov VV, Riemer J (2022). Spatial and temporal control of mitochondrial H2O2 release in intact human cells. EMBO J, e109169.
• Gibhardt CS, Riemer J, Bogeski I (2022). Calcium and redox signals at mitochondrial interfaces: A nanoview perspective. Cell Calcium 103:102550.
• Hermeling, J.C., Herholz, M., Baumann, L., Cores, E.C., Zecic, A., Hoppe, T., Riemer, J., and Trifunovic, A. (2022). Mitochondria-originated redox signalling regulates KLF-1 to promote longevity in Caenorhabditis elegans. Redox Biol58, 102533. 10.1016/j.redox.2022.102533.
• Mai, M., Niemeier, J.O., Hoffmann, M., Zimmermann, J., Riemer, J., Roma, L.P., Schwarzlaender, M., and Morgan, B. (2022). Novel H2o2 and Nadph Probes to Dissect Subcellular Redox Processes in Plants. Free Radical Bio Med189, 2-2.
• Nanadikar, M., Leon, A.M.V., Guo, J., van Belle, G., Jatho, A., Bradner, A., Bockmann, R., Runzhu, S., Brodesser, S., Schmidtendorf, M., Lee, J., Wu, H., Furdui, C., Burgoyne, J., Bogeski, I., Riemer, J., Chowdhury, A., Rehling, P., Brugmann, T., Belousov, V., and Katschinski, D. (2022). IDH3 gamma serves as a redox switch that regulates mitochondrial energy metabolism and contractility in the heart under oxidative stress. Acta Physiol236, 183-185.

Elena Rugarli

• Wani GA, Sprenger HG, Ndoci K, Chandragiri S, Acton RJ, Schatton D, Kochan SMV, Sakthivelu V, Jevtic M, Seeger JM, Müller S, Giavalisco P, Rugarli EI, Motori E, Langer T, Bergami M (2022). Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.Cell Rep. 2022 Feb 15;38(7):110370. doi: 10.1016/j.celrep.2022.110370. PMID: 35172139.
• Schatton D, Di Pietro G, Szczepanowska K, Veronese M, Marx MC, Braunöhler K, Barth E, Müller S, Giavalisco P,Langer T, Trifunovic A, Rugarli EI (2022). CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife. 2022 May 13;11:e74552. doi: 10.7554/eLife.74552. Epub ahead of print. PMID: 35559794.
• Ralevski A, Apelt F, Olas JJ, Mueller-Roeber B, Rugarli EI, Kragler F, Horvath TL (2022). Plant mitochondrial FMT and its mammalian homolog CLUH controls development and behavior in Arabidopsis and locomotion in mice. Cell Mol Life Sci. , 2022 Jun 2;79(6):334. doi: 10.1007/s00018-022-04382-3. PMID: 35652974.
• Patron M, Tarasenko D, Nolte H, Kroczek L, Ghosh M, Ohba Y, Lasarzewski Y, Ahmadi ZA, Cabrera-Orefice A, Eyiama A, Kellermann T, Rugarli EI, Brandt U, Meinecke M, Langer T (2022). Regulation of mitochondrial proteostasis by the proton gradient. EMBO J. 2022 Aug 16;41(16):e110476. doi: 10.15252/embj.2021110476. Epub Aug 1. PMID: 35912435; PMCID: PMC9379554.

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Bernhard Schermer

• Kroef V, Ruegenberg S, Horn M, Allmeroth K, Ebert L, Bozkus S, Miethe S, Elling U, Schermer B, Baumann U, Denzel M.S (2022). GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway. Elife 11. e69223. doi.org/10.7554/eLife.69223.
• Unnersjö-Jess D, Ramdedovic A, Höhne M, Butt L, Koehler F.C, Müller R.-U, Hoyer P.F, Blom H, Schermer B, Benzing T (2022). Three-Dimensional Super-Resolved Imaging of Paraffin-Embedded Kidney Samples. Kidney360 3. 446–454. doi.org/10.34067/KID.0005882021.
• Koehler S, Odenthal J, Ludwig V, Unnersjö Jess D, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku J.L, Bergmann C, Hoyer P.F, Hagmann H.H, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T, Iden S, Brinkkoetter P.T (2022). Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int 101. 733–751. doi.org/10.1016/j.kint.2021.11.030.
• Butt L, Unnersjö-Jess D, Höhne M, Hahnfeldt R, Reilly D, Rinschen MM, Plagmann I, Diefenhardt P, Brähler S, Brinkkötter PT, Brismar H, Blom H, Schermer B, Benzing T (2021). Super-Resolution Imaging of the Filtration Barrier Suggests a Role for Podocin R229Q in Genetic Predisposition to Glomerular Disease. J Am Soc Nephrol. 2022 Jan;33(1):138-154. doi: 10.1681/ASN.2020060858. Epub 2021 Dec 1. PMID: 34853150.
• Koehler FC, Fu CY, Späth MR, Hoyer-Allo KJR, Bohl K, Göbel H, Lackmann JW, Grundmann F, Osterholt T, Gloistein C, Steiner JD, Antebi A, Benzing T, Schermer B, Schwarz G, Burst V, Müller RU (2022). A systematic analysis of diet-induced nephroprotection reveals overlapping changes in cysteine catabolism. Transl Res. 2022 Feb 18:S1931-5244(22)00023-8. doi: 10.1016/j.trsl.2022.02.003. Epub ahead of print. PMID: 35189406.
• Reusch B, Bartram MP, Dafinger C, Palacio-Escat N, Wenzel A, Fenton RA, Saez-Rodriguez J, Schermer B, Benzing T, Altmüller J, Beck BB, Rinschen MM (2022). MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells. J Proteomics. 2022 Feb 10;252:104424. doi: 10.1016/j.jprot.2021.104424. Epub 2021 Nov 12. PMID: 34775100. 
• Hoyer-Allo KJR, Späth MR, Brodesser S, Zhu Y, Binz-Lotter J, Höhne M, Brönneke H, Bohl K, Johnsen M, Kubacki T, Kiefer K, Seufert L, Koehler FC, Grundmann F, Hackl MJ, Schermer B, Brüning J, Benzing T, Burst V, Müller RU (2022). Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury. Kidney Int. 2022 May 30:S0085-2538(22)00386-6. doi: 10.1016/j.kint.2022.04.033. Epub ahead of print. PMID: 35654224.

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Björn Schumacher

• Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.
• Umansky C, Morellato AE, Rieckher M, Scheidegger MA, Martinefski MR, Fernández GA, Pak O, Kolesnikova K, Reingruber H, Bollini M, Crossan GP, Sommer N, Monge ME, Schumacher B, Pontel LB (2022). Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity. Nat Commun. 2022 Feb 8;13(1):745. doi: 10.1038/s41467-022-28242-7. PMID: 35136057; PMCID: PMC8827065.
• Soltanmohammadi N, Wang S, Schumacher B (2022). Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy. Nat Commun. 2022 Feb 4;13(1):701. doi: 10.1038/s41467-022-28225-8. PMID: 35121747; PMCID: PMC8816960. 
• Volatier T, Schumacher B, Cursiefen C, Notara M (2022). UV Protection in the Cornea: Failure and Rescue. Biology (Basel). 2022 Feb 10;11(2):278. doi: 10.3390/biology11020278. PMID: 35205145; PMCID: PMC8868636.
• Volatier, T., Kluth, A., Masslo, C., Ganss, C., Frank, M.H., Frank, N., Schumacher, B., Notara, M., and Cursiefen, C. (2022). UVB activates autophagy in corneal epithelial stem cells. Invest Ophth Vis Sci63.
• Vaddavalli PL, Schumacher B (2022). The p53 network: cellular and systemic DNA damage responses in cancer and aging. Trends Genet. 2022 Mar 25:S0168-9525(22)00037-3. doi: 10.1016/j.tig.2022.02.010. Epub ahead of print. PMID: 35346511. 
• Kasper P, Selle J, Vohlen C, Wilke R, Kuiper-Makris C, Klymenko O, Bae-Gartz I, Schömig C, Quaas A, Schumacher B, Demir M, Bürger M, Lang S, Martin A, Steffen HM, Goeser T, Dötsch J, Alcazar MAA (2022). Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice. Int J Mol Sci. 2022 May 17;23(10):5609. doi: 10.3390/ijms23105609. PMID: 35628414; PMCID: PMC9144113.

Eline Slagboom

• Albalak G, Stijntjes M, Wijsman CA, Slagboom PE, van der Ouderaa FJ, Mooijaart SP, van Heemst D, Noordam R (2022). Timing of objectively-collected physical activity in relation to body weight and metabolic health in sedentary older people: a cross-sectional and prospective analysis. Int J Obes (Lond). 2022 Mar;46(3):515-522. doi: 10.1038/s41366-021-01018-7. PMID: 34782736.
• Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, van den Akker EB (2022). MiMIR: R-shiny application to infer risk factors and endpoints from Nightingale Health's 1H-NMR Metabolomics data. Bioinformatics. 2022 Jun 13:btac388. doi: 10.1093/bioinformatics/btac388. PMID: 35695757.
• Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, Bbmri-Nl, van den Akker EB (2022). 1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints. EBioMedicine. 2022 Jan;75:103764. doi: 10.1016/j.ebiom.2021.103764. PMID: 34942446; PMCID: PMC8703237.
• Bogaards FA, Gehrmann T, Beekman M, van den Akker EB, van de Rest O, Hangelbroek RWJ, Noordam R, Mooijaart SP, de Groot LCPGM, Reinders MJT, Slagboom PE (2022). PLIS: A metabolomic response monitor to a lifestyle intervention study in older adults. FASEB J. 2022 Nov;36(11):e22578. doi: 10.1096/fj.202201037R. PMID: 36183353.
• Buergel T, Steinfeldt J, Ruyoga G, Pietzner M, Bizzarri D, Vojinovic D, Upmeier Zu Belzen J, Loock L, Kittner P, Christmann L, Hollmann N, Strangalies H, Braunger JM, Wild B, Chiesa ST, Spranger J, Klostermann F, van den Akker EB, Trompet S, Mooijaart SP, Sattar N, Jukema JW, Lavrijssen B, Kavousi M, Ghanbari M, Ikram MA, Slagboom E, Kivimaki M, Langenberg C, Deanfield J, Eils R, Landmesser U (2022). Metabolomic profiles predict individual multidisease outcomes. Nat Med. 2022 Sep 22. doi: 10.1038/s41591-022-01980-3. PMID: 36138150.
• Hop PJ, Zwamborn RAJ, Hannon E, Shireby GL, Nabais MF, Walker EM, van Rheenen W, van Vugt JJFA, Dekker AM, Westeneng HJ, Tazelaar GHP, van Eijk KR, Moisse M, Baird D, Al Khleifat A, Iacoangeli A, Ticozzi N, Ratti A, Cooper-Knock J, Morrison KE, Shaw PJ, Basak AN, Chiò A, Calvo A, Moglia C, Canosa A, Brunetti M, Grassano M, Gotkine M, Lerner Y, Zabari M, Vourc'h P, Corcia P, Couratier P, Mora Pardina JS, Salas T, Dion P, Ross JP, Henderson RD, Mathers S, McCombe PA, Needham M, Nicholson G, Rowe DB, Pamphlett R, Mather KA, Sachdev PS, Furlong S, Garton FC, Henders AK, Lin T, Ngo ST, Steyn FJ, Wallace L, Williams KL; BIOS Consortium; Brain MEND Consortium, Neto MM, Cauchi RJ, Blair IP, Kiernan MC, Drory V, Povedano M, de Carvalho M, Pinto S, Weber M, Rouleau GA, Silani V, Landers JE, Shaw CE, Andersen PM, McRae AF, van Es MA, Pasterkamp RJ, Wray NR, McLaughlin RL, Hardiman O, Kenna KP, Tsai E, Runz H, Al-Chalabi A, van den Berg LH, Van Damme P, Mill J, Veldink JH, Heijmans BT, T Hoen PAC, van Meurs J, Jansen R, Franke L, Boomsma DI, Pool R, van Dongen J, Hottenga JJ, van Greevenbroek MMJ, Stehouwer CDA, van der Kallen CJH, Schalkwijk CG, Wijmenga C, Franke L, Zhernakova S, Tigchelaar EF, Slagboom PE, Beekman M, Deelen J, van Heemst D, Veldink JH, van den Berg LH, van Duijn CM, Hofman BA, Isaacs A, Uitterlinden AG, van Meurs J, Jhamai PM, Verbiest M, Suchiman HED, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Mei H, van Iterson M, van Galen M, Bot J, Zhernakova DV, Jansen R, van 't Hof P, Deelen P, Nooren I, T Hoen PAC, Heijmans BT, Moed M, Franke L, Vermaat M, Zhernakova DV, Luijk R, Jan Bonder M, van Iterson M, Deelen P, van Dijk F, van Galen M, Arindrarto W, Kielbasa SM, Swertz MA, van Zwet EW, Jansen R, T Hoen PAC, Heijmans BT, Al-Chalabi A, Wray NR, Bensimon G, Hardiman O, Chio A, Veldink JH, Smith GD, Mill J (2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Sci Transl Med. 2022 Feb 23;14(633):eabj0264. doi: 10.1126/scitranslmed.abj0264. PMID: 35196023.
• Jonkman TH, Dekkers KF, Slieker RC, Grant CD, Ikram MA, van Greevenbroek MMJ, Franke L, Veldink JH, Boomsma DI, Slagboom PE, Consortium BIOS, Heijmans BT (2022). Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression. Genome Biol. 2022 Jan 14;23(1):24. doi: 10.1186/s13059-021-02585-8. PMID: 35031073; PMCID: PMC8759260.
• Kananen L, Hurme M, Bürkle A, Moreno-Villanueva M, Bernhardt J, Debacq-Chainiaux F, Grubeck-Loebenstein B, Malavolta M, Basso A, Piacenza F, Collino S, Gonos ES, Sikora E, Gradinaru D, Jansen EHJM, Dollé MET, Salmon M, Stuetz W, Weber D, Grune T, Breusing N, Simm A, Capri M, Franceschi C, Slagboom E, Talbot D, Libert C, Raitanen J, Koskinen S, Härkänen T, Stenholm S, Ala-Korpela M, Lehtimäki T, Raitakari OT, Ukkola O, Kähönen M, Jylhä M, Jylhävä J (2022). Circulating cell-free DNA in health and disease - the relationship to health behaviours, ageing phenotypes and metabolomics. Geroscience. 2022 Jul 21. doi: 10.1007/s11357-022-00590-8. PMID: 35864375.
• Morwani-Mangnani J, Giannos P, Belzer C, Beekman M, Slagboom PE, Prokopidis K (2022). Gut microbiome changes due to sleep disruption in older and younger individuals: a case for sarcopenia? Sleep. 2022 Oct 2:zsac239. doi: 10.1093/sleep/zsac239. PMID: 36183306.
• Niehues A, Bizzarri D, Reinders MJT, Slagboom PE, van Gool AJ, van den Akker EB; BBMRI-NL BIOS consortium; BBMRI-NL Metabolomics consortium, 't Hoen PAC (2022). Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies. BMC Genomics. 2022 Jul 31;23(1):546. doi: 10.1186/s12864-022-08771-7. PMID: 35907790.
• Odintsova VV, Suderman M, Hagenbeek FA, Caramaschi D, Hottenga JJ, Pool R; BIOS Consortium, Dolan CV, Ligthart L, van Beijsterveldt CEM, Willemsen G, de Geus EJC, Beck JJ, Ehli EA, Cuellar-Partida G, Evans DM, Medland SE, Relton CL, Boomsma DI, van Dongen J (2022). DNA methylation in peripheral tissues and left-handedness. Sci Rep. 2022 Apr 4;12(1):5606. doi: 10.1038/s41598-022-08998-0. PMID: 35379837.
• Wielscher M, Mandaviya PR, Kuehnel B, Joehanes R, Mustafa R, Robinson O, Zhang Y, Bodinier B, Walton E, Mishra PP, Schlosser P, Wilson R, Tsai PC, Palaniswamy S, Marioni RE, Fiorito G, Cugliari G, Karhunen V, Ghanbari M, Psaty BM, Loh M, Bis JC, Lehne B, Sotoodehnia N, Deary IJ, Chadeau-Hyam M, Brody JA, Cardona A, Selvin E, Smith AK, Miller AH, Torres MA, Marouli E, Gào X, van Meurs JBJ, Graf-Schindler J, Rathmann W, Koenig W, Peters A, Weninger W, Farlik M, Zhang T, Chen W, Xia Y, Teumer A, Nauck M, Grabe HJ, Doerr M, Lehtimäki T, Guan W, Milani L, Tanaka T, Fisher K, Waite LL, Kasela S, Vineis P, Verweij N, van der Harst P, Iacoviello L, Sacerdote C, Panico S, Krogh V, Tumino R, Tzala E, Matullo G, Hurme MA, Raitakari OT, Colicino E, Baccarelli AA, Kähönen M, Herzig KH, Li S; BIOS consortium, Conneely KN, Kooner JS, Köttgen A, Heijmans BT, Deloukas P, Relton C, Ong KK, Bell JT, Boerwinkle E, Elliott P, Brenner H, Beekman M, Levy D, Waldenberger M, Chambers JC, Dehghan A, Järvelin MR (2022). DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases. Nat Commun. 2022 May 3;13(1):2408. doi: 10.1038/s41467-022-29792-6.PMID: 35504910.
• Wiersema JM, Kamphuis AEP, Rohling JHT, Kervezee L, Akintola AA, Jansen SW, Slagboom PE, van Heemst D, van der Spoel E (2022). The association between continuous ambulatory heart rate, heart rate variability, and 24-h rhythms of heart rate with familial longevity and aging. Aging (Albany NY). 2022 Aug 16;14(18):7223-7239. doi: 10.18632/aging.204219. PMID: 35980264

Phillipp Steven

• Balla, A., Tran, B., Valtari, A., Steven, P., Scarpellini, C., Augustyns, K., Urtti, A., Vellonen, K.S., and Ruponen, M. (2022). A Novel Ferroptosis Inhibitor UAMC-3203, a Potential Treatment for Corneal Epithelial Wound. Pharmaceutics15. 10.3390/pharmaceutics15010118.
• Setu MAK, Schmidt S, Musial G, Stern ME, Steven P (2022). Segmentation and Evaluation of Corneal Nerves and Dendritic Cells From In Vivo Confocal Microscopy Images Using Deep Learning. Transl Vis Sci Technol. 2022 Jun 1;11(6):24. doi: 10.1167/tvst.11.6.24. PMID: 35762938; PMCID: PMC9251793.
• Gehlsen U, Faust C, Blecha C, Dietrich-Ntoukas T, Eberwein P, Issleib S, Meyer-Ter-Vehn T, Braun R, Westekemper H, Steven P (2022). Outcomes and complications of cataract surgery in patients with chronic ocular graft-versus-host-disease-a multicenter, retrospective analysis. Graefes Arch Clin Exp Ophthalmol. Aug;260(8):2613-2622. doi: 10.1007/s00417-022-05613-w. Epub 2022 Mar 7. PMID: 35254513; PMCID: PMC9325851.
• Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P (2022). Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease. Transplant Cell Ther. Jul 31:S2666-6367(22)01514-7. doi: 10.1016/j.jtct.2022.07.027. Epub ahead of print. PMID: 35921986.
• Katsinas N, Gehlsen U, García-Posadas L, Rodríguez-Rojo S, Steven P, González-García MJ, Enríquez-de-Salamanca A (2022). Olive Pomace Phenolic Compounds: From an Agro-Industrial By-Product to a Promising Ocular Surface Protection for Dry Eye Disease. J Clin Med. 2022 Aug 11;11(16):4703. doi: 10.3390/jcm11164703. PMID: 36012942; PMCID: PMC9409789.
• Musial G, Kohlfaerber T, Ahrens M, Schulz-Hildebrandt H, Steven P, Hüttmann G (2022). Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride. Transl Vis Sci Technol. 2022 May 2;11(5):28. doi: 10.1167/tvst.11.5.28. PubMed PMID: 35622381; PubMed Central PMCID: PMC9145126.
• Tran BN, Maass M, Musial G, Stern ME, Gehlsen U, Steven P (2022). Topical application of cannabinoid-ligands ameliorates experimental dry-eye disease. Ocul Surf. 2022 Jan;23:131-139. doi: 10.1016/j.jtos.2021.12.008. Epub 2021 Dec 16. PubMed PMID: 34922011.

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Peter Tessarz

• Demetriadou C, Raoukka A, Charidemou E, Mylonas C, Michael C, Parekh S, Koufaris C, Skourides P, Papageorgis P, Tessarz P, Kirmizis A (2022). Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance. Oncogene. 2022 Jan;41(4):571-585. doi: 10.1038/s41388-021-02113-9. Epub 2021 Nov 16. PMID: 34785778; PMCID: PMC8782725.
• Gehling K, Parekh S, Schneider F, Kirchner M, Kondylis V, Nikopoulou C, Tessarz P (2022). RNA-sequencing of single cholangiocyte-derived organoids reveals high organoid-to organoid variability. Life Sci Alliance. Aug 1;5(12):e202101340. doi: 10.26508/lsa.202101340. PMID: 35914813; PMCID: PMC9348635.
• Bozukova M, Nikopoulou C, Kleinenkuhnen N, Grbavac D, Goetsch K, Tessarz P (2022). Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver. Mol Syst Biol. 2022 Sep;18(9):e11002. doi: 10.15252/msb.202211002. PMID: 36082605; PMCID: PMC9459415.
• Pouikli A, MaleszewskaM, ParekhS, Yang M, NikopoulouC, BonfiglioJJ, MylonasC, SandovalT, SchumacherA-L, HinzeY, MaticI, Frezza C and TessarzP (2022).Hypoxia promotes osteogenesis via regulating the acetyl-CoA-mediated mito-nuclear communication.  EMBO J. 41: e111239.
• Conte M, Eletto D, Pannetta M, Petrone AM, Monti MC, Cassiano C, Giurato G, Rizzo F , Tessarz P, Petrella A, Tosco A and Porta A (2022). Effect of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysis. Front Cell Infect Microbiol. 12:1031814.
• Skowronska-Krawczyk D, Narayan P and Tessarz P (2022). Editorial: Molecular Role of Lipids in Aging. Front Aging. 3:946884.
• GroßbachJ, GilletL, Clément-ZizaM, SchmalohrCL, SchubertOT, SchütterM, MawerJSP, BarnesCA, BludauI, WeithM, TessarzP, GraefM, AebersoldR, BeyerA (2022).The impact of genomic variation on protein phosphorylation states and regulatory networks. Mol Syst  Biol. 18:e10712.
• Pouikli A and Tessarz P (2022).Epigenetic alterations in stem cell ageing - a promising target for age-reversing interventions? Brief Funct Gen.21 (1), 35–42.

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Marc Tittgemeyer

• Hanssen R, Thanarajah SE, Tittgemeyer M, Brüning JC (2022). Obesity - A Matter of Motivation? Exp Clin Endocrinol Diabetes. 2022 Feb 18. doi: 10.1055/a-1749-4852. Epub ahead of print. PMID: 35181879.
• Trempler I, Binder E, Reuter M, Plieger T, Standke I, Mecklenbrauck F, Meinert S, Forstner AJ, Nöthen MM, Rietschel M, Stürmer S, Dannlowski U, Tittgemeyer M, Lencer R, Fink GR, Schubotz RI (2022). Effects of DRD2/ANKK1 and COMT Val158Met polymorphisms on stabilization against and adaptation to unexpected events. Cereb Cortex. 2022 Mar 2:bhac046. doi: 10.1093/cercor/bhac046. Epub ahead of print. PMID: 35235645.
• Pelzer EA, Stürmer S, Feis DL, Melzer C, Schwartz F, Scharge M, Eggers C, Tittgemeyer M, Timmermann L (2022). Clustering of Parkinson subtypes reveals strong influence of DRD2 polymorphism and gender. Sci Rep. 2022 Apr 11;12(1):6038. doi: 10.1038/s41598-022-09657-0. PMID: 35411010; PMCID: PMC9001640.
• Steidel K, Ruppert MC, Greuel A, Tahmasian M, Maier F, Hammes J, van Eimeren T, Timmermann L, Tittgemeyer M,Drzezga A, Pedrosa DJ, Eggers C (2022).Longitudinal trimodal imaging of midbrain-associated network degeneration in Parkinson's disease. NPJ Parkinsons Dis. 2022 Jun 22;8(1):79. doi: 10.1038/s41531-022-00341-8. PMID: 35732679; PMCID: PMC9218128.
• Oren S, Tittgemeyer M, Rigoux L, Schlamann M, Schonberg T, Kuzmanovic B (2022). Neural encoding of food and monetary reward delivery. Neuroimage. 2022 Aug 15;257:119335. doi: 10.1016/j.neuroimage.2022.119335. Epub 2022 May 26. PMID: 35643268.
• Loehrer P.A, Weber I, Oehrn C.R, Nettersheim F.S, Dafsari H.S, Knake S, Tittgemeyer M, Timmermann L, Belke M (2022). Microstructural alterations predict impaired bimanual control in Parkinson’s disease. Brain Commun. 4, fcac137-.
• Ophey A, Krohm F, Kalbe E, Greuel A, Drzezga A, Tittgemeyer M, Timmermann L, Jessen F, Eggers C, and Maier F (2022). Neural correlates and predictors of subjective cognitive decline in patients with Parkinson’s disease. Neurol Sci. 43, 3153–3163.
• Richter N, David L.S, Grothe M.J, Teipel S, Dietlein M, Tittgemeyer M, Neumaier B, Fink G.R, Onur O.A, and Kukolja J (2022). Age and Anterior Basal Forebrain Volume Predict the Cholinergic Deficit in Patients with Mild Cognitive Impairment due to Alzheimer’s Disease. J Alzheimer’s Dis. 86, 425–440.
• Weber J.P.D, Spiro J.E, Scheffler M, Wolf J, Nogova L, Tittgemeyer M, Maintz D, Laue H, and Persigehl T (2022). Reproducibility of dynamic contrast enhanced MRI derived transfer coefficient Ktrans in lung cancer. Plos One.17, e0265056.

Débora B. Trentini Schmidt

• Eisenack, T.J., and Trentini, D.B. (2022). Ending a bad start: Triggers and mechanisms of co-translational protein degradation. Front Mol Biosci9, 1089825. 10.3389/fmolb.2022.1089825.

Achim Tresch

• Baar T, Dümcke S, Gressel S, Schwalb B, Dilthey A, Cramer P, Tresch A (2022). RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history. G3 (Bethesda).2022 Mar 7:jkac054. doi: 10.1093/g3journal/jkac054. Epub ahead of print. PMID: 35253846.
• Hussainy M, Korsching SI, Tresch A (2022). Pseudotime analysis reveals novel regulatory factors for multigenic onset and monogenic transition of odorant receptor expression. Sci Rep. 2022 Sep 28;12(1):16183. doi: 10.1038/s41598-022-20106-w. PMID: 36171231; PMCID: PMC9519747.
• Rosendahl, A.S., Schonborn, K., Baar, T., Kleinenkuhnen, N., Tresch, A., Eckes, B., Moinzadeh, P., and Krieg, T. (2022). Single cell RNA sequencing reveals specific subsets in Systemic Sclerosis fibroblast cultures. J Invest Dermatol142, S182-S182.
• Werner, D.J., Wenzel, N., Abusalim, N., Kiesslich, R., Baar, T., Tresch, A., and Rey, J.W. (2022). Unmasking lower gastrointestinal bleeding under administration of norepinephrine. World J Radiol14, 375-383. 10.4329/wjr.v14.i12.375.

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Aleksandra Trifunovic

• Rumyantseva A, Popovic M, Trifunovic A (2022). CLPP deficiency ameliorates neurodegeneration caused by impaired mitochondrial protein synthesis. Brain. 2022 Mar 29;145(1):92-104. doi: 10.1093/brain/awab303. PMID: 35240691.
• Hoehne MN, Jacobs LJHC, Lapacz KJ, Calabrese G, Murschall LM, Marker T, Kaul H, Trifunovic A, Morgan B, Fricker M, Belousov VV, Riemer J (2022). Spatial and temporal control of mitochondrial H₂ O₂ release in intact human cells. EMBO J. 2022 Apr 4;41(7):e109169. doi: 10.15252/embj.2021109169. Epub 2022 Feb 11. PMID: 35146782; PMCID: PMC8982624.
• Croon M, Szczepanowska K, Popovic M, Lienkamp C, Senft K, Brandscheid CP, Bock T, Gnatzy-Feik L, Ashurov A, Acton RJ, Kaul H, Pujol C, Rosenkranz S,Krüger M, Trifunovic A (2022).FGF21 modulates mitochondrial stress response in cardiomyocytes only under mild mitochondrial dysfunction. Sci Adv. 2022 Apr 8;8(14):eabn7105. doi: 10.1126/sciadv.abn7105. Epub 2022 Apr 6. PMID: 35385313; PMCID: PMC8986112.
• Schatton D, Di Pietro G, Szczepanowska K, Veronese M, Marx MC, Braunöhler K, Barth E, Müller S, Giavalisco P,Langer T, Trifunovic A, Rugarli EI (2022). CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression. Elife. 2022 May 13;11:e74552. doi: 10.7554/eLife.74552. Epub ahead of print. PMID: 35559794.
• Salscheider SL, Gerlich S, Cabrera-Orefice A, Peker E, Rothemann RA, Murschall LM, Finger Y, Szczepanowska K, Ahmadi ZA, Guerrero-Castillo S, Erdogan A, Becker M, Ali M, Habich M, Petrungaro C, Burdina N, Schwarz G, Klußmann M, Neundorf I, Stroud DA, Ryan MT, Trifunovic A, Brandt U, Riemer J (2022). AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5. EMBO J. Sep 1;41(17):e110784. doi: 10.15252/embj.2022110784. Epub 2022 Jul 20. PMID: 35859387; PMCID: PMC9434101.
• Ravanelli S, Li Q, Annibal A, Trifunovic A, Antebi A, Hoppe T (2022). Reprograming of proteasomal degradation by branched chain amino acid metabolism. Aging Cell. 2022 Sep 27:e13725. doi: 10.1111/acel.13725. Epub ahead of print. PMID: 36168305.
• Gonzalez-Franquesa, A., Gama-Perez, P., Kulis, M., Szczepanowska, K., Dahdah, N., Moreno-Gomez, S., Latorre-Pellicer, A., Fernandez-Ruiz, R., Aguilar-Mogas, A., Hoffman, A., Monelli, E., Samino, S., Miro-Blanch, J., Oemer, G., Duran, X., Sanchez-Rebordelo, E., Schneeberger, M., Obach, M., Montane, J., Castellano, G., Chapaprieta, V., Sun, W.F., Navarro, L., Prieto, I., Castano, C., Novials, A., Gomis, R., Monsalve, M., Claret, M., Graupera, M., Soria, G., Wolfrum, C., Vendrell, J., Fernandez-Veledo, S., Enriquez, J.A., Carracedo, A., Perales, J.C., Nogueiras, R., Herrero, L., Trifunovic, A., Keller, M.A., Yanes, O., Sales-Pardo, M., Guimera, R., Bluher, M., Martin-Subero, J.I., and Garcia-Roves, P.M. (2022). Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. Redox Biol54. ARTN 102353. 10.1016/j.redox.2022.102353.
• Hermeling, J.C., Herholz, M., Baumann, L., Cores, E.C., Zecic, A., Hoppe, T., Riemer, J., and Trifunovic, A. (2022). Mitochondria-originated redox signalling regulates KLF-1 to promote longevity in Caenorhabditis elegans. Redox Biol58, 102533. 10.1016/j.redox.2022.102533.
• Szczepanowska, K., and Trifunovic, A. (2022). Mitochondrial matrix proteases: quality control and beyond. Febs Journal289, 7128-7146. 10.1111/febs.15964.
• Trifunovic, A. (2022). Proteolytic regulation of mitochondrial function. Bba-Bioenergetics1863, 85-85. 10.1016/j.bbabio.2022.148841.
• Willenborg, S., Sanin, D.E., Jais, A., Ding, X., Ulas, T., Nuchel, J., Popovic, M., MacVicar, T., Langer, T., Schultze, J.L., Roers, A., Pearce, E.J., Bruning, J.C., Trifunovic, A., and Eming, S.A. (2022). Metabolic reprogramming coordinates dynamics of myeloid cell function in skin repair. Exp Dermatol31, E62-E62.
• Willenborg, S., Sanin, D.E., Jais, A., Schultze, J.L., Roers, A., Pearce, E.J., Bruning, J.C., Trifunovic, A., and Eming, S.A. (2022). Healthy repair of injured skin requires mitochondrial repurposing in wound macrophages. J Invest Dermatol142, S235-S235.

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Mirka Uhlirova

• Külshammer E, Kilinc M, Csordás G, Bresser T, Nolte H, Uhlirova M (2022). The mechanosensor Filamin A/Cheerio promotes tumourigenesis via specific interactions with components of the cell cortex. FEBS J. 2022 Feb 21. doi: 10.1111/febs.16408. Epub ahead of print. PMID: 35191183.

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Dario Valenzano

• Bradshaw, W.J., Poeschla, M., Placzek, A., Kean, S., and Valenzano, D.R. (2022). Extensive age-dependent loss of antibody diversity in naturally short-lived turquoise killifish. Elife11. ARTN e65117. 10.7554/eLife.65117.
• Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye-Knudsen M (2022). Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022 Jan 28;14(2):530-543. doi: 10.18632/aging.203859. Epub 2022 Jan 28. PMID: 35089871; PMCID: PMC8833115.
• Promislow D, Anderson RM, Scheffer M, Crespi B, DeGregori J, Harris K, Horowitz BN, Levine ME, Riolo MA, Schneider DS, Spencer SL, Valenzano DR, Hochberg ME (2022). Resilience integrates concepts in aging research. iScience. 2022 Apr 6;25(5):104199. doi: 10.1016/j.isci.2022.104199. PMID: 35494229; PMCID: PMC9044173.

David Vilchez

• Balaji V, Müller L, Lorenz R, Kevei E, Zhang WH, Santiago U, Gebauer J, Llamas E, Vilchez D, Camacho CJ, Pokrzywa W, Hoppe T (2022). A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing. Molecular Cell.  doi.org/10.1016/j.molcel.2022.08.003. PMID: 36027913
• Hommen, F., Bilican, S., and Vilchez, D. (2022). Protein clearance strategies for disease intervention. J Neural Transm (Vienna)129, 141-172. 10.1007/s00702-021-02431-y.
• Zhang WH, Koyuncu S, Vilchez D (2022). Insights Into the Links Between Proteostasis and Aging From C. elegans. Front Aging. Mar 18;3:854157. doi: 10.3389/fragi.2022.854157. PMID: 35821832; PMCID: PMC9261386.

Johannes Vogt

• Barham, M., Andermahr, J., Majczynski, H., Slawinska, U., Vogt, J., and Neiss, W.F. (2022). Treadmill training of rats after sciatic nerve graft does not alter accuracy of muscle reinnervation. Front Neurol13, 1050822. 10.3389/fneur.2022.1050822.
• Barham, M., Streppel, M., Guntinas-Lichius, O., Fulgham-Scott, N., Vogt, J., and Neiss, W.F. (2022). Treatment With Nimodipine or FK506 After Facial Nerve Repair Neither Improves Accuracy of Reinnervation Nor Recovery of Mimetic Function in Rats. Front Neurosci16, 895076. 10.3389/fnins.2022.895076.
• Hanuscheck N, Thalman C, Domingues M, Schmaul S, Muthuraman M, Hetsch F, Ecker M, Endle H, Oshagi M, Martino G, Kuhlmann T, Bozek K, van Beers T, Bittner S, von Engelhardt J, Vogt J*, Vogelaar CF*, Zipp F* (2022). Interleukin-4 receptor signaling modulates neuronal network activity. Journal of ExperimentalMedicine. Doi  10.1084/jem.20211887*contributed equally as senior authors.
• Endle H, Horta G, Stutz B, Muthuraman M, Tegeder I, Schreiber Y, Snodgrass IF, Gurke R, Liu ZW, Sestan-Pesa M, Radyushkin K, Streu N, Fan W, Baumgart J, Li Y, Kloss F, Groppa S, Opel N, Dannlowski U, Grabe HJ, Zipp F, Rácz B, Horvath TL*^#, Nitsch R*^# & Vogt J*^# (2022).Lysophosphatidic acid species under AgRP neuronal control alter cortical synaptic transmission and food intake Nature Metabolism. Vol 4, June: 683-692*contributed equally as senior author #correspondence authors.
• Bitar L, Uphaus T, Thalman C, Muthuraman M, Gyr L, Ji H, Domingues M, Endle H, Groppa S, Steffen F, Koirala N, Fan W, Ibanez L, Heitsch L, Cruchaga C, Lee JM, Kloss F, Bittner S, Nitsch R, Zipp F, Vogt J (2022).Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke. Sci Transl Med. 2022 Apr 20;14(641):eabk0135. doi: 10.1126/scitranslmed.abk0135. Epub 2022 Apr 20. PMID: 35442704.

Silvia von Karstedt

• Seidel E, von Karstedt S (2022). Extrinsic Cell Death Pathway Plasticity: A driver of Clonal Evolution in Cancer? Cell Death Discovery. (accepted in principle).
• Montinaro, A., Zubiaur, I.A., Saggau, J., Kretz, A.L., Ferreira, R.M.M., Hassan, O., Kitzig, E., Muller, I., El-Bahrawy, M.A., von Karstedt, S., Kulms, D., Liccardi, G., Lemke, J., and Walczak, H. (2022). Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers. Cell Death Differ29, 492-503. 10.1038/s41418-021-00869-x.

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Henning Walczak

• Theobald SJ, Simonis A, Mudler JM, Göbel U, Acton R, Kohlhas V, Albert M-C, Hellmann A-M, Malin JJ, Winter S, Hallek M, Walczak H, Nguyen P-H, Koch M, Rybniker J (2022). Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS-CoV-2 mRNA vaccination. EMBO Molecular Medicine. 14, e15888.
• Petricevic B, Kabiljo J, Zirnbauer R, Walczak H, Laengle J, Bergmann M (2022). Neoadjuvant immunotherapy in gastrointestinal cancers - The new standard of care? Semin Cancer Biol. 86(Pt 2):834-850.
• Li X, Huang CH, Sánchez-Rivera FJ, Kennedy MC, Tschaharganeh DF, Morris JP 4th, Montinaro A, O'Rourke KP, Banito A, Wilkinson JE, Chen CC, Ho YJ, Dow LE, Tian S, Luan W, de Stanchina E, Zhang T, Gray NS, Walczak H, Lowe SW (2022). A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets. Proceedings of the National Academy of Sciences. 119, e2110557119.
• Zinngrebe J, Moepps B, Monecke T, Gierschik P, Schlichtig F, Barth TFE, Strauß G, Boldrin E, Posovszky C, Schulz A, Beringer O, Rieser E, Jacobsen EM, Lorenz MR, Schwarz K, Pannicke U, Walczak H, Niessing D, Schuetz C, Fischer-Posovszky P, Debatin KM (2022). Compound heterozygous variants in OTULIN are associated with fulminant atypical late‐onset ORAS. EMBO Molecular Medicine. 14, e14901.
• Bolik J, Krause F, Stevanovic M, Gandraß M, Thomsen I, Schacht SS, Rieser E, Müller M, Schumacher N, Fritsch J, Wichert R, Galun E, Bergmann J, Röder C, Schafmayer C, Egberts JH, Becker-Pauly C, Saftig P, Lucius R, Schneider-Brachert W, Barikbin R, Adam D, Voss M, Hitzl W, Krüger A, Strilic B, Sagi I, Walczak H, Rose-John S, Schmidt-Arras D (2022). Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis. J Exp Med. 219(1):e20201039.
• Montinaro A, Areso Zubiaur I, Saggau J, Kretz AL, Ferreira RMM, Hassan O, Kitzig E, Müller I, El-Bahrawy MA, von Karstedt S, Kulms D, Liccardi G, Lemke J, Walczak H (2022). Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers. Cell Death & Differentiation. 29, 492-503.

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Sara Wickstroem

• Martin, I.M., Nava, M.M., Wickström, S.A., and Gräter, F. (2022). ATP allosterically stabilizes integrin-linked kinase for efficient force generation. P Natl Acad Sci USA119. ARTN e2106098119. 10.1073/pnas.2106098119.
• Miroshnikova, Y.A., and Wickström, S.A. (2022). Mechanical Forces in Nuclear Organization. Csh Perspect Biol14. ARTN a039685. 10.1101/cshperspect.a039685.
• Rübsam, M., Püllen, R., Telkamp, F., Bianco, A., Pescoller, M., Bloch, W., Green, K.J., Merkel, R., Hoffmann, B., Wickström, S., and Niessen, C. (2022). aPKC is a rheostat that controls basal junctional dynamics and suprabasal cytoskeletal organization essential for epidermal dynamics and integrity. J Invest Dermatol142, S212-S212.

Rudolf Wiesner

• Sen, A., S. Kallabis, F. Gaedke, C. Jüngst, J. Boix, J. Nüchel, K. Maliphol, J. Hofmann, A. Schauss, M. Krüger, R.J. Wiesner and D. Pla-Martin (2022): Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA. NatureCommunications 2022 Nov 7;13(1):6704. doi: 10.1038/s41467-022-34205-9.
• Franko A, Irmler M, Prehn C, Heinzmann SS, Schmitt-Kopplin P, Adamski J, Beckers J, von Kleist-Retzow JC,Wiesner R, Häring HU, Heni M, Birkenfeld AL, de Angelis MH (2022). Bezafibrate Reduces Elevated Hepatic Fumarate in Insulin-Deficient Mice. Biomedicines. 2022 Mar 6;10(3):616. doi: 10.3390/biomedicines10030616. PMID: 35327418; PMCID: PMC8945094.
• Urbanczyk S, Baris OR, Hofmann J, Taudte RV, Guegen N, Golombek F, Castiglione K, Meng X, Bozec A, Thomas J, Weckwerth L, Mougiakakos D, Schulz SR, Schuh W, Schlötzer-Schrehardt U, Steinmetz TD, Brodesser S, Wiesner RJ, Mielenz D (2022).Mitochondrial respiration in B lymphocytes is essential for humoral immunity by controlling the flux of the TCA cycle. Cell Rep. 2022 Jun 7;39(10):110912. doi: 10.1016/j.celrep.2022.110912. PMID: 35675769.
• Kimoloi S, Sen A, Guenther S, Braun T, Brügmann T, Sasse P, Wiesner RJ, Pla-Martín D, Baris OR (2022). Combined fibre atrophy and decreased muscle regeneration capacity driven by mitochondrial DNA alterations underlie the development of sarcopenia. J Cachexia Sarcopenia Muscle. 2022 Jun 28. doi: 10.1002/jcsm.13026. Epub ahead of print. PMID: 35765148.
• Hippen, M., Zsurka, G., Peeva, V., Machts, J., Schwiecker, K., Debska-Vielhaber, G., Wiesner, R.J., Vielhaber, S., and Kunz, W.S. (2022). Novel Pathogenic Sequence Variation m.5789T>C Causes NARP Syndrome and Promotes Formation of Deletions of the Mitochondrial Genome. Neurol Genet8, e660. 10.1212/NXG.0000000000000660.

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Andreas Wodarz

• Pryymachuk G, El-Awaad E, Piekarek N, Drebber U, Maul AC, Hescheler J, Wodarz A, Pfitzer G, Neiss WF, Pietsch M, Schroeter MM (2022). Angiotensin II type 1 receptor localizes at the blood-bile barrier in humans and pigs. Histochem Cell Biol. 2022 Feb 28. doi: 10.1007/s00418-022-02087-z. Epub ahead of print. PMID: 35229169.
• Koehler, S., Odenthal, J., Ludwig, V., Jess, D.U., Höhne, M., Jüngst, C., Grawe, F., Helmstädter, M., Janku, J.L., Bergmann, C., Hoyer, P.F., Hagmann, H.H., Walz, G., Bloch, W., Niessen, C., Schermer, B., Wodarz, A., Denholm, B., Benzing, T., Iden, S., and Brinkkoetter, P.T. (2022). Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int101, 733-751. 10.1016/j.kint.2021.11.030.

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Thomas Wunderlich

• Werr L, Plenker D, Dammert MA, Lorenz C, Brägelmann J, Tumbrink HL, Klein S, Schmitt A, Büttner R, Persigehl T, Shokat KM, Wunderlich FT, Schram AM, Peifer M, Sos ML, Reinhardt HC, Thomas RK (2022). CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization. Mol Cancer Ther. 2022 May 4;21(5):821-830. doi: 10.1158/1535-7163.MCT-21-0820. PMID: 35247925.
• Selle, J., Dinger, K., Jentgen, V., Zanetti, D., Will, J., Georgomanolis, T., Vohlen, C., Wilke, R., Kojonazarov, B., Klymenko, O., Mohr, J., S, V.K.-R., Rhodes, C.J., Ulrich, A., Hirani, D., Nestler, T., Odenthal, M., Mahabir, E., Nayakanti, S., Dabral, S., Wunderlich, T., Priest, J., Seeger, W., Dotsch, J., Pullamsetti, S.S., and Alejandre Alcazar, M.A. (2022). Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. Nat Commun13, 4352. 10.1038/s41467-022-31655-z.

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Branko Zevnik

• Tröder SE, Zevnik B (2022). Simple electroporation for efficient CRISPR/Cas9 genome editing in murine zygotes V.4. Protocols.oi. Jan doi: 10.17504/protocols.io.b4dyqs7w.
• Tröder SE, Zevnik B (2022). History of genome editing: From meganucleases to CRISPR. Lab Anim.  Feb;56(1):60-68. doi: 10.1177/0023677221994613. PMID: 33622064.
• Stephan A, Rehberg M, Tröder S, Zevnik B, Niehoff A, Etich J, Semler O, Zaucke F (2022). Homozygous Kdelr2-mutant mice display defects in endochondral and intramembranous bone development. Bone Reports. May 1;16:10128
• Zevnik B, Jerchow B, Buch T (2022). 3R measures in facilities for the production of genetically modified rodents. Lab Anim (NY). Jun;51(6):162-177. doi: 10.1038/s41684-022-00978-1. PMID: 35641635.
• Jiao H, Wachsmuth L, Wolf S, Lohmann J, Nagata M, Kaya GG, Oikonomou N, Kondylis V, Rogg M, Diebold M, Tröder SE, Zevnik B, Prinz M, Schell C, Young GR, Kassiotis G, Pasparakis M (2022). ADAR1 averts fatal type I interferon induction by ZBP1. Nature. Jul;607(7920):776-783. doi: 10.1038/s41586-022-04878-9. PMID: 35859176; PMCID: PMC9329096.

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