Adam Antebi
- Baum, E., Huang, W., Vincent-Delorme, C., Brunelle, P., Antebi, A., and Dafsari, H.S. (2024). Novel Genetic and Phenotypic Expansion in Ameliorated PUF60-Related Disorders. Int J Mol Sci25. 10.3390/ijms25042053.
- Calabrese, C., Nolte, H., Pitman, M.R., Ganesan, R., Lampe, P., Laboy, R., Ripa, R., Fischer, J., Polara, R., Panda, S.K., Chipurupalli, S., Gutierrez, S., Thomas, D., Pitson, S.M., Antebi, A., and Robinson, N. (2024). Mitochondrial translocation of TFEB regulates complex I and inflammation. EMBO Rep25, 704-724. 10.1038/s44319-024-00058-0.
- Horikawa, M., Fukuyama, M., Antebi, A., and Mizunuma, M. (2024). Regulatory mechanism of cold-inducible diapause in Caenorhabditis elegans. Nat Commun15, 5793. 10.1038/s41467-024-50111-8.
- Hu, Q., Xu, Y., Song, M., Dai, Y., Antebi, A., and Shen, Y. (2024). BLMP-1 is a critical temporal regulator of dietary-restriction-induced response in Caenorhabditis elegans. Cell Rep43, 113959. 10.1016/j.celrep.2024.113959.
- Lyu, Y.X., Fu, Q., Wilczok, D., Ying, K., King, A., Antebi, A., Vojta, A., Stolzing, A., Moskalev, A., Georgievskaya, A., Maier, A.B., Olsen, A., Groth, A., Simon, A.K., Brunet, A., Jamil, A., Kulaga, A., Bhatti, A., Yaden, B., Pedersen, B.K., Schumacher, B., Djordjevic, B., Kennedy, B., Chen, C., Huang, C.Y., Correll, C.U., Murphy, C.T., Ewald, C.Y., Chen, D., Valenzano, D.R., Soldacki, D., Erritzoe, D., Meyer, D., Sinclair, D.A., Chini, E.N., Teeling, E.C., Morgen, E., Verdin, E., Vernet, E., Pinilla, E., Fang, E.F., Bischof, E., Mercken, E.M., Finger, F., Kuipers, F., Pun, F.W., Gyulveszi, G., Civiletto, G., Zmudze, G., Blander, G., Pincus, H.A., McClure, J., Kirkland, J.L., Peyer, J., Justice, J.N., Vijg, J., Gruhn, J.R., McLaughlin, J., Mannick, J., Passos, J., Baur, J.A., Betts-LaCroix, J., Sedivy, J.M., Speakman, J.R., Shlain, J., von Maltzahn, J., Andreasson, K.I., Moody, K., Palikaras, K., Fortney, K., Niedernhofer, L.J., Rasmussen, L.J., Veenhoff, L.M., Melton, L., Ferrucci, L., Quarta, M., Koval, M., Marinova, M., Hamalainen, M., Unfried, M., Ringel, M.S., Filipovic, M., Topors, M., Mitin, N., Roy, N., Pintar, N., Barzilai, N., Binetti, P., Singh, P., Kohlhaas, P., Robbins, P.D., Rubin, P., Fedichev, P.O., Kamya, P., Munoz-Canoves, P., de Cabo, R., Faragher, R.G.A., Konrad, R., Ripa, R., Mansukhani, R., Buttner, S., Wickstrom, S.A., Brunemeier, S., Jakimov, S., Luo, S., Rosenzweig-Lipson, S., Tsai, S.Y., Dimmeler, S., Rando, T.A., Peterson, T.R., Woods, T., Wyss-Coray, T., Finkel, T., Strauss, T., Gladyshev, V.N., Longo, V.D., Dwaraka, V.B., Gorbunova, V., Acosta-Rodriguez, V.A., Sorrentino, V., Sebastiano, V., Li, W., Suh, Y., Zhavoronkov, A., Scheibye-Knudsen, M., and Bakula, D. (2024). Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity. Aging (Albany NY)16, 12955-12976. 10.18632/aging.206135.
- Papantonis, A., Antebi, A., Partridge, L., and Beyer, A. (2024). Age-associated changes in transcriptional elongation and their effects on homeostasis. Trends Cell Biol10.1016/j.tcb.2024.11.005. 10.1016/j.tcb.2024.11.005.
- Wang, X., Jiang, Q., Zhang, H., He, Z., Song, Y., Chen, Y., Tang, N., Zhou, Y., Li, Y., Antebi, A., Wu, L., Han, J.J., and Shen, Y. (2024). Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans. Nat Commun15, 955. 10.1038/s41467-024-45249-4.
- Deneubourg, C., Salimi Dafsari, H., Lowe, S., Martinez-Cotrina, A., Mazaud, D., Park, S.H., Vergani, V., Almacellas Barbanoj, A., Maroofian, R., Averdunk, L., Ghayoor-Karimiani, E., Jayawant, S., Mignot, C., Keren, B., Peters, R., Kamath, A., Mattas, L., Verma, S., Silwal, A., Distelmaier, F., Houlden, H., Lignani, G., Antebi, A., Jepson, J., Jungbluth, H., and Fanto, M. (2025). Epg5 links proteotoxic stress due to defective autophagic clearance and epileptogenesis in Drosophila and Vici syndrome patients. Autophagy21, 447-459. 10.1080/15548627.2024.2405956.
Miguel A. Alejandre Alcazar
- Hamdorf, M., Imhof, T., Bailey-Elkin, B., Betz, J., Theobald, S.J., Simonis, A., Di Cristanziano, V., Gieselmann, L., Dewald, F., Lehmann, C., Augustin, M., Klein, F., Alejandre Alcazar, M.A., Rongisch, R., Fabri, M., Rybniker, J., Goebel, H., Stetefeld, J., Brachvogel, B., Cursiefen, C., Koch, M., and Bock, F. (2024). The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm. J Mol Cell Biol15. 10.1093/jmcb/mjad062.
- Jirmo, A.C., Albrecht, M., Crnkovic, S., and Alcazar, M.A.A. (2024). Cellular and systemic interplay of metabolism and inflammation in the pathogenesis of lung diseases. Frontiers in Immunology14. ARTN 1352304. 10.3389/fimmu.2023.1352304.
- Nusken, E., Voggel, J., Saschin, L., Weber, L.T., Dotsch, J., Alcazar, M.A.A., and Nusken, K.D. (2024). Kidney lipid metabolism: impact on pediatric kidney diseases and modulation by early-life nutrition. Pediatr Nephrol10.1007/s00467-024-06595-z. 10.1007/s00467-024-06595-z.
Hisham Bazzi
- Boix, J., Knuever, J., Niehoff, N., Sen, A., Pla-Martin, D., Baris, O.R., Etich, J., Brachvogel, B., Kaul, H., Isbrandt, D., Soroka, E., Bazzi, H., Wenger, R.H., Giavalisco, P., and Wiesner, R.J. (2024). Constitutive HIF-1alpha Expression in the Epidermis Fuels Proliferation and Is Essential for Effective Barrier Formation. J Invest Dermatol. 10.1016/j.jid.2024.09.022.
- Camblor-Perujo, S., Ozer Yildiz, E., Kupper, H., Overhoff, M., Rastogi, S., Bazzi, H., and Kononenko, N.L. (2024). The AP-2 complex interacts with gamma-TuRC and regulates the proliferative capacity of neural progenitors. Life Sci Alliance7. 10.26508/lsa.202302029.
- Grzonka, M., and Bazzi, H. (2024). Mouse SAS-6 is required for centriole formation in embryos and integrity in embryonic stem cells. Elife13. 10.7554/eLife.94694.
- Khatif, H., and Bazzi, H. (2024). Generation and characterization of a Dkk4-Cre knock-in mouse line. Genesis62, e23532. 10.1002/dvg.23532.
- Meyer-Gerards, C., and Bazzi, H. (2024). Developmental and tissue-specific roles of mammalian centrosomes. FEBS J. 10.1111/febs.17212. 10.1111/febs.17212.
Stephan Baldus
- Acar, L., Behrendt, C.A., Baldus, S., Falk, V., Smetak, N., Nzomo, M.M., Marschall, U., and Girdauskas, E. (2024). Prognostic impact of disease-related complications in asymptomatic mitral regurgitation: a health insurance claims analysis. Clin Res Cardiol10.1007/s00392-024-02532-0. 10.1007/s00392-024-02532-0.
- Baldus, S., Doenst, T., Pfister, R., Gummert, J., Kessler, M., Boekstegers, P., Lubos, E., Schroder, J., Thiele, H., Walther, T., Kelm, M., Hausleiter, J., Eitel, I., Fischer-Rasokat, U., Bufe, A., Schmeisser, A., Ince, H., Lurz, P., von Bardeleben, R.S., Hagl, C., Noack, T., Reith, S., Beucher, H., Reichenspurner, H., Rottbauer, W., Schulze, P.C., Muller, W., Frank, J., Hellmich, M., Wahlers, T., Rudolph, V., and Investigators, M. (2024). Transcatheter Repair versus Mitral-Valve Surgery for Secondary Mitral Regurgitation. N Engl J Med391, 1787-1798. 10.1056/NEJMoa2408739.
- Finke, K., Gietzen, T., Steven, D., Baldus, S., Ten Freyhaus, H., Maintz, D., Pennig, L., and Gietzen, C. (2024). Cardiac fibromas in adult patients: a case series focusing on rhythmology and radiographic features. Eur Heart J Case Rep8, ytae410. 10.1093/ehjcr/ytae410.
- Finke, K., Meertens, M.M., Macherey-Meyer, S., Heyne, S., Braumann, S., Baldus, S., Lee, S., and Adler, C. (2024). Exercise related versus non exercise related out of hospital cardiac arrest - A retrospective single-center study. Resusc Plus19, 100742. 10.1016/j.resplu.2024.100742.
- Geissen, S., Braumann, S., Adler, J., Nettersheim, F.S., Mehrkens, D., Hof, A., Guthoff, H., von Stein, P., Witkowski, S., Gerdes, N., Tellkamp, F., Kruger, M., Isermann, L., Trifunovic, A., Bunck, A.C., Mollenhauer, M., Winkels, H., Adam, M., Klinke, A., Buch, G., Ten Cate, V., Hellmich, M., Kelm, M., Rudolph, V., Wild, P.S., Rosenkranz, S., and Baldus, S. (2024). Inhibition of myeloperoxidase to treat left ventricular dysfunction in non-ischaemic cardiomyopathy. Eur J Heart Fail26, 2269-2281. 10.1002/ejhf.3435.
- Gramespacher, H., Schmieschek, M.H.T., Warnke, C., Adler, C., Bittner, S., Dronse, J., Richter, N., Zaeske, C., Gietzen, C., Schlamann, M., Baldus, S., Fink, G.R., and Onur, O.A. (2024). Analysis of Cerebral CT Based on Supervised Machine Learning as a Predictor of Outcome After Out-of-Hospital Cardiac Arrest. Neurology103, e209583. 10.1212/WNL.0000000000209583.
- Heyne, S., Macherey-Meyer, S., Meertens, M.M., Finke, K., Baldus, S., Adler, C., and Lee, S. (2024). Oral anticoagulation in patients with left ventricular thrombus: a systematic review and network meta-analysis with reconstructed time-to-event data. Clin Res Cardiol10.1007/s00392-024-02547-7. 10.1007/s00392-024-02547-7.
- Hoeper, M.M., Oerke, B., Wissmuller, M., Leuchte, H., Opitz, C., Halank, M., Seyfarth, H.J., Baldus, S., Bauersachs, J., Bohm, M., Ghofrani, H.A., Konstantinides, S., Olsson, K.M., Wachter, R., Lam, C.S.P., Aminossadati, B., and Rosenkranz, S. (2024). Tadalafil for Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction: A Randomized Controlled Phase 3 Study. Circulation150, 600-610. 10.1161/CIRCULATIONAHA.124.069340.
- Macherey-Meyer, S., Salem, K., Heyne, S., Meertens, M.M., Finke, K., Mauri, V., Baldus, S., Adler, C., and Lee, S. (2024). Percutaneous Coronary Intervention versus Optimal Medical Therapy in Patients with Chronic Total Occlusion: A Meta-Analysis. J Clin Med13. 10.3390/jcm13102919.
- Nies, R.J., Nettersheim, F.S., Braumann, S., Ney, S., Ochs, L., Dohr, J., Nies, J.F., Wienemann, H., Adam, M., Mauri, V., Baldus, S., and Rosenkranz, S. (2024). Right ventricular dysfunction and impaired right ventricular-pulmonary arterial coupling in paradoxical low-flow, low-gradient aortic stenosis. Eur J Heart Fail26, 2340-2352. 10.1002/ejhf.3329.
- Peters, V.B.M., Matheis, F., Erdmann, I., Nemade, H.N., Muders, D., Toubartz, M., Torun, M., Mehrkens, D., Geissen, S., Nettersheim, F.S., Picard, F., Guthoff, H., Hof, A., Arkenberg, P., Arand, B., Klinke, A., Rudolph, V., Hansen, H.P., Bachurski, D., Adam, M., Hoyer, F.F., Winkels, H., Baldus, S., and Mollenhauer, M. (2024). Myeloperoxidase induces monocyte migration and activation after acute myocardial infarction. Front Immunol15, 1360700. 10.3389/fimmu.2024.1360700.
- Poletti, E., Adam, M., Wienemann, H., Sisinni, A., Patel, K.P., Amat-Santos, I.J., Orzalkiewicz, M., Saia, F., Regazzoli, D., Fiorina, C., Panoulas, V., Brinkmann, C., Giordano, A., Taramasso, M., Maisano, F., Barbanti, M., De Backer, O., Van Mieghem, N.M., Latib, A., Squillace, M., Baldus, S., Geyer, M., Baumbach, A., Bedogni, F., Rudolph, T.K., and Testa, L. (2024). Performance of Purpose-Built vs Off-Label Transcatheter Devices for Aortic Regurgitation: The PURPOSE Study. JACC Cardiovasc Interv17, 1597-1606. 10.1016/j.jcin.2024.05.019.
- Popovic, M., Isermann, L., Geissen, S., Senft, K., Georgomanolis, T., Baldus, S., Frezza, C., and Trifunovic, A. (2024). Tissue-specific adaptations to cytochrome c oxidase deficiency shape physiological outcomes. Biochim Biophys Acta Mol Basis Dis1871, 167567. 10.1016/j.bbadis.2024.167567.
- von Stein, J., Pfister, R., Baldus, S., and Iliadis, C. (2024). Heterotopic Transcatheter Tricuspid Valve-in-Valve Replacement in a Transplanted Heart. JACC Cardiovasc Interv17, 1948-1951. 10.1016/j.jcin.2024.05.035.
- von Stein, J., von Stein, P., Gietzen, T., Althoff, J., Hasse, C., Metze, C., Iliadis, C., Gercek, M., Kalbacher, D., Kirchner, J., Rudolph, F., Koll, B., Rudolph, V., Baldus, S., Pfister, R., and Korber, M.I. (2024). Performance of Transcatheter Direct Annuloplasty in Patients With Atrial and Nonatrial Functional Tricuspid Regurgitation. JACC Cardiovasc Interv17, 1470-1481. 10.1016/j.jcin.2024.04.013.
- von Stein, P., Wienemann, H., von Stein, J., Sugiura, A., Tanaka, T., Kavsur, R., Ozturk, C., Weber, M., Haurand, J.M., Horn, P., Kister, T., Mahabadi, A.A., Boeder, N., Ruf, T., Gercek, M., Mues, C., Grothusen, C., Novotny, J., Weckbach, L., Guthoff, H., Rudolph, F., Polzin, A., Baldus, S., Rassaf, T., Thiele, H., Mollmann, H., Kelm, M., Rudolph, V., von Bardeleben, R.S., Nef, H., Luedike, P., Lurz, P., Hausleiter, J., Pfister, R., and Mauri, V. (2024). Early Outcomes of Two Large Mitral Valve Transcatheter Edge-to-Edge Repair Devices-A Propensity Score Matched Multicenter Comparison. J Clin Med13. 10.3390/jcm13144187.
- Wissmuller, M., Wartner, V., Hohmann, C., Adler, J., Kramer, T., Hellmich, M., Gerhardt, F., Baldus, S., and Rosenkranz, S. (2024). Reply to: The puzzles surrounding the impact of face masks on 6-minute walking distance in pulmonary hypertension. Eur Respir J63. 10.1183/13993003.00529-2024.
- Zheng, R., Moynahan, K., Georgomanolis, T., Pavlenko, E., Geissen, S., Mizi, A., Grimm, S., Nemade, H., Rehimi, R., Bastigkeit, J., Lackmann, J.W., Adam, M., Rada-Iglesias, A., Nuernberg, P., Klinke, A., Poepsel, S., Baldus, S., Papantonis, A., and Kargapolova, Y. (2024). Remodeling of the endothelial cell transcriptional program via paracrine and DNA-binding activities of MPO. iScience27, 108898. 10.1016/j.isci.2024.108898.
- Zierden, M., Berghausen, E.M., Gnatzy-Feik, L., Millarg, C., Picard, F.S.R., Kiljan, M., Geissen, S., Polykratis, A., Zimmermann, L., Nies, R.J., Pasparakis, M., Baldus, S., Valasarajan, C., Pullamsetti, S.S., Winkels, H., Vantler, M., and Rosenkranz, S. (2024). Hematopoietic PI3Kdelta deficiency aggravates murine atherosclerosis through impairment of Tregs. Jci Insight9. 10.1172/jci.insight.155626.
- von Stein, P., von Stein, J., Hohmann, C., Wienemann, H., Guthoff, H., Korber, M.I., Baldus, S., Pfister, R., Hahn, R.T., and Iliadis, C. (2025). Atrial Functional Mitral Regurgitation Subtypes Undergoing Transcatheter Edge-to-Edge Repair: Suboptimal Outcomes in Atriogenic Hamstringing. JACC Cardiovasc Imaging18, 16-29. 10.1016/j.jcmg.2024.06.019.
To top
Matteo Bergami
- Franchino, C.A., Motori, E., and Bergami, M. (2024). Janus-faced Mitofusin 2 (MFN2): mitochondria-endoplasmic reticulum shaping and tethering functions unveiled. Signal Transduct Target Ther9, 4. 10.1038/s41392-023-01730-y.
- Kochan, S.M.V., Malo, M.C., Jevtic, M., Jahn-Kelleter, H.M., Wani, G.A., Ndoci, K., Perez-Revuelta, L., Gaedke, F., Schaffner, I., Lie, D.C., Schauss, A., and Bergami, M. (2024). Enhanced mitochondrial fusion during a critical period of synaptic plasticity in adult-born neurons. Neuron112, 1997-2014 e1996. 10.1016/j.neuron.2024.03.013.
To top
Thomas Benzing
- Czogalla, J., Schliffke, S., Lu, S., Schwerk, M., Petereit, H., Zhang, T., Liu, S., Dumoulin, B., Gies, S., Wu, G., Hanzelmann, S., Bode, M., Grahammer, F., Godel, M., Voigtlander, M., Butt, L., Bokemeyer, C., Bergmann, C., Benzing, T., Wiech, T., Puelles, V.G., and Huber, T.B. (2024). Ibrutinib-associated focal segmental glomerulosclerosis and the impact of podocin mutations in chronic lymphocytic leukemia. Kidney Int105, 877-881. 10.1016/j.kint.2024.02.001.
- Ferring, A., Muck, L., Stegemann, J., Wiebe, L., Becker, I., Benzing, T., Meyer, A.M., and Polidori, M.C. (2024). Prognostic Features of Sarcopenia in Older Hospitalized Patients: A 6-Month Follow-Up Study. J Clin Med13. 10.3390/jcm13113116.
- Hochleitner, M., Pickert, L., Nolting, N.A., Affeldt, A.M., Becker, I., Benzing, T., Kochanek, M., and Polidori, M.C. (2024). Patient- vs organ-based prognostic tools for older patients in critical care units : An observational study with a 3-month follow-up. Med Klin Intensivmed Notfmed10.1007/s00063-024-01179-z. 10.1007/s00063-024-01179-z.
- Nies, J.F., Hendrix, C., Bartram, M.P., Spear, R., Hagmann, H., Benzing, T., and Kubacki, T. (2024). Effectiveness and safety of immunoadsorption as a rescue treatment of inflammatory myopathies: report of three cases and literature review. Ther Adv Musculoskelet Dis16, 1759720X241250238. 10.1177/1759720X241250238.
- Rutkowski, N., Gorlitz, F., Wiesner, E., Binz-Lotter, J., Feil, S., Feil, R., Benzing, T., and Hackl, M.J. (2024). Real-time imaging of cGMP signaling shows pronounced differences between glomerular endothelial cells and podocytes. Sci Rep14, 26099. 10.1038/s41598-024-76768-1.
- Schomig, T., Diefenhardt, P., Plagmann, I., Trinsch, B., Merz, T., Crispatzu, G., Unnersjo-Jess, D., Nies, J., Putz, D., Sierra Gonzalez, C., Schermer, B., Benzing, T., Brinkkoetter, P.T., and Brahler, S. (2024). The podocytes' inflammatory responses in experimental GN are independent of canonical MYD88-dependent toll-like receptor signaling. Sci Rep14, 2292. 10.1038/s41598-024-52565-8.
- Stegemann, J., Affeldt, A.M., Muck, L., Ferring, A., Gerhards, L., Pickert, L., Bausch, A., Benzing, T., Antczak, P., and Polidori, M.C. (2024). Prognostic signature of multimorbidity, geriatric syndromes and resources cluster in older in- and outpatients: a pooled secondary analysis with a 6-month follow-up. BMJ Open14, e086975. 10.1136/bmjopen-2024-086975.
- Verleysdonk, J., Noetzel, N., Becker, I., Pickert, L., Benzing, T., Pfister, R., Polidori, M.C., and Affeldt, A.M. (2024). Profiles of Geriatric Syndromes and Resources in Older Patients with Atrial Fibrillation. J Clin Med13. 10.3390/jcm13144009.
- Wiesner, E., Binz-Lotter, J., Hackl, A., Unnersjo-Jess, D., Rutkowski, N., Benzing, T., and Hackl, M.J. (2024). Correlative multiphoton-STED microscopy of podocyte calcium levels and slit diaphragm ultrastructure in the renal glomerulus. Sci Rep14, 13019. 10.1038/s41598-024-63507-9.
To top
Andreas Beyer
- Avila, P.U., Padvitski, T., Leote, A.C., Chen, H., Saez-Rodriguez, J., Kann, M., and Beyer, A. (2024). Gene regulatory networks in disease and ageing. Nature Reviews Nephrology. 10.1038/s41581-024-00849-7.
- Leote, A.C., Lopes, F., and Beyer, A. (2024). Loss of coordination between basic cellular processes in human aging. Nat Aging4, 1432-1445. 10.1038/s43587-024-00696-y.
- Palikyras, S., Sofiadis, K., Stavropoulou, A., Danieli-Mackay, A., Varamogianni-Mamatsi, V., Horl, D., Nasiscionyte, S., Zhu, Y., Papadionysiou, I., Papadakis, A., Josipovic, N., Zirkel, A., O'Connell, A., Loughran, G., Keane, J., Michel, A., Wagner, W., Beyer, A., Harz, H., Leonhardt, H., Lukinavicius, G., Nikolaou, C., and Papantonis, A. (2024). Rapid and synchronous chemical induction of replicative-like senescence via a small molecule inhibitor. Aging Cell23, e14083. 10.1111/acel.14083.
- Papantonis, A., Antebi, A., Partridge, L., and Beyer, A. (2024). Age-associated changes in transcriptional elongation and their effects on homeostasis. Trends Cell Biol10.1016/j.tcb.2024.11.005. 10.1016/j.tcb.2024.11.005.
- Unger Avila, P., Padvitski, T., Leote, A.C., Chen, H., Saez-Rodriguez, J., Kann, M., and Beyer, A. (2024). Gene regulatory networks in disease and ageing. Nat Rev Nephrol20, 616-633. 10.1038/s41581-024-00849-7.
- Zhong, Q., Sun, R., Aref, A.T., Noor, Z., Anees, A., Zhu, Y., Lucas, N., Poulos, R.C., Lyu, M., Zhu, T., Chen, G.B., Wang, Y., Ding, X., Rutishauser, D., Rupp, N.J., Rueschoff, J.H., Poyet, C., Hermanns, T., Fankhauser, C., Rodriguez Martinez, M., Shao, W., Buljan, M., Neumann, J.F., Beyer, A., Hains, P.G., Reddel, R.R., Robinson, P.J., Aebersold, R., Guo, T., and Wild, P.J. (2024). Proteomic-based stratification of intermediate-risk prostate cancer patients. Life Sci Alliance7. 10.26508/lsa.202302146.
- Traulsen, A., Rasmussen, M.N., Krug, J., and Beyer, A. (2025). On the misuse of evolutionary theory to bolster the 'scientific' case for intelligent design: A cautionary note. J Theor Biol596, 111985. 10.1016/j.jtbi.2024.111985.
To top
Kasia Bozek
- Ibruli, O., Rose, F., Beleggia, F., Schmitt, A., Cartolano, M., Fernandez, L.T., Saggau, J., Bonasera, D., Kiljan, M., Gozum, G., Lichius, L., Cai, J., Niu, L.N., Caiaffa, M.I., Herter, J.M., Walczak, H., Liccardi, G., Grull, H., Buttner, R., Bosco, G., George, J., Thomas, R.K., Bozek, K., Reinhardt, H.C., and Herter-Sprie, G.S. (2024). A novel mouse model recapitulating the MMR-defective SCLC subtype uncovers an actionable sensitivity to immune checkpoint blockade. J Cancer Res Clin Oncol150, 496. 10.1007/s00432-024-05942-9.
- Naji, H., Sancere, L., Simon, A., Buttner, R., Eich, M.L., Lohneis, P., and Bozek, K. (2024). HoLy-Net: Segmentation of histological images of diffuse large B-cell lymphoma. Comput Biol Med170, 107978. 10.1016/j.compbiomed.2024.107978.
- Weng, Z., Seper, A., Pryalukhin, A., Mairinger, F., Wickenhauser, C., Bauer, M., Glamann, L., Blaker, H., Lingscheidt, T., Hulla, W., Jonigk, D., Schallenberg, S., Bychkov, A., Fukuoka, J., Braun, M., Schomig-Markiefka, B., Klein, S., Thiel, A., Bozek, K., Netto, G.J., Quaas, A., Buttner, R., and Tolkach, Y. (2024). GrandQC: A comprehensive solution to quality control problem in digital pathology. Nat Commun15, 10685. 10.1038/s41467-024-54769-y.
To top
Bent Brachvogel
- Boix, J., Knuever, J., Niehoff, N., Sen, A., Pla-Martin, D., Baris, O.R., Etich, J., Brachvogel, B., Kaul, H., Isbrandt, D., Soroka, E., Bazzi, H., Wenger, R.H., Giavalisco, P., and Wiesner, R.J. (2024). Constitutive HIF-1alpha Expression in the Epidermis Fuels Proliferation and Is Essential for Effective Barrier Formation. J Invest Dermatol10.1016/j.jid.2024.09.022.
- Bopp, L., Martinez, M.L., Schumacher, C., Seitz, R., Arana, M.H., Klapproth, H., Lukas, D., Oh, J.H., Neumayer, D., Lackmann, J.W., Mueller, S., von Stebut, E., Brachvogel, B., Brodesser, S., Klein Geltink, R.I., and Fabri, M. (2024). Glutamine promotes human CD8(+) T cells and counteracts imiquimod-induced T cell hyporesponsiveness. iScience27, 109767. 10.1016/j.isci.2024.109767.
- Hamdorf, M., Imhof, T., Bailey-Elkin, B., Betz, J., Theobald, S.J., Simonis, A., Di Cristanziano, V., Gieselmann, L., Dewald, F., Lehmann, C., Augustin, M., Klein, F., Alejandre Alcazar, M.A., Rongisch, R., Fabri, M., Rybniker, J., Goebel, H., Stetefeld, J., Brachvogel, B., Cursiefen, C., Koch, M., and Bock, F. (2024). The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm. J Mol Cell Biol15. 10.1093/jmcb/mjad062.
- Pass, T., Ricke, K.M., Hofmann, P., Chowdhury, R.S., Nie, Y., Chinnery, P., Endepols, H., Neumaier, B., Carvalho, A., Rigoux, L., Steculorum, S.M., Prudent, J., Riemer, T., Aswendt, M., Liss, B., Brachvogel, B., and Wiesner, R.J. (2024). Preserved striatal innervation maintains motor function despite severe loss of nigral dopaminergic neurons. Brain147, 3189-3203. 10.1093/brain/awae089.
- Reiter, L., Niehoff, N., Weiland, D., Helbig, D., Eming, S.A., Krieg, T., Etich, J., Brachvogel, B., Wiesner, R.J., and Knuever, J. (2024). Mitochondrial DNA mutations attenuate Bleomycin-induced dermal fibrosis by inhibiting differentiation into myofibroblasts. Matrix Biol132, 72-86. 10.1016/j.matbio.2024.07.002.
- Schmidt, L., Saynisch, M., Hoegsbjerg, C., Schmidt, A., Mackey, A., Lackmann, J.W., Muller, S., Koch, M., Brachvogel, B., Kjaer, M., Antczak, P., and Kruger, M. (2024). Spatial proteomics of skeletal muscle using thin cryosections reveals metabolic adaptation at the muscle-tendon transition zone. Cell Rep43, 114374. 10.1016/j.celrep.2024.114374.
To top
Jens Brüning
- Ardanaz, C.G., de la Cruz, A., Minhas, P.S., Hernandez-Martin, N., Pozo, M.A., Valdecantos, M.P., Valverde, A.M., Villa-Valverde, P., Elizalde-Horcada, M., Puerta, E., Ramirez, M.J., Ortega, J.E., Urbiola, A., Ederra, C., Ariz, M., Ortiz-de-Solorzano, C., Fernandez-Irigoyen, J., Santamaria, E., Karsenty, G., Bruning, J.C., and Solas, M. (2024). Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis. Sci Adv10, eadp1115. 10.1126/sciadv.adp1115.
- De Solis, A.J., Del Rio-Martin, A., Radermacher, J., Chen, W., Steuernagel, L., Bauder, C.A., Eggersmann, F.R., Morgan, D.A., Cremer, A.L., Sue, M., Germer, M., Kukat, C., Vollmar, S., Backes, H., Rahmouni, K., Kloppenburg, P., and Bruning, J.C. (2024). Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism. Nat Metab6, 473-493. 10.1038/s42255-024-00987-z.
- Dodt, S., Widdershooven, N.V., Dreisow, M.L., Weiher, L., Steuernagel, L., Wunderlich, F.T., Bruning, J.C., and Fenselau, H. (2024). NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation. Nat Commun15, 5439. 10.1038/s41467-024-49766-0.
- Engstrom Ruud, L., Font-Girones, F., Zajdel, J., Kern, L., Teixidor-Deulofeu, J., Manneras-Holm, L., Carreras, A., Becattini, B., Bjorefeldt, A., Hanse, E., Fenselau, H., Solinas, G., Bruning, J.C., Wunderlich, T.F., Backhed, F., and Ruud, J. (2024). Activation of GFRAL(+) neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor. Cell Rep43, 113960. 10.1016/j.celrep.2024.113960.
- Henschke, S., Nolte, H., Magoley, J., Kleele, T., Brandt, C., Hausen, A.C., Wunderlich, C.M., Bauder, C.A., Aschauer, P., Manley, S., Langer, T., Wunderlich, F.T., and Bruning, J.C. (2024). Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver. Science384, 438-446. 10.1126/science.adk1005.
- Leon, S., Simon, V., Lee, T.H., Steuernagel, L., Clark, S., Biglari, N., Leste-Lasserre, T., Dupuy, N., Cannich, A., Bellocchio, L., Zizzari, P., Allard, C., Gonzales, D., Le Feuvre, Y., Lhuillier, E., Brochard, A., Nicolas, J.C., Teillon, J., Nikolski, M., Marsicano, G., Fioramonti, X., Bruning, J.C., Cota, D., and Quarta, C. (2024). Single cell tracing of Pomc neurons reveals recruitment of 'Ghost' subtypes with atypical identity in a mouse model of obesity. Nat Commun15, 3443. 10.1038/s41467-024-47877-2.
- Sotelo-Hitschfeld, T., Minere, M., Klemm, P., Borgmann, D., Wnuk-Lipinski, D., Jais, A., Jia, X., Corneliussen, S., Kloppenburg, P., Fenselau, H., and Bruning, J.C. (2024). GABAergic disinhibition from the BNST to PNOC(ARC) neurons promotes HFD-induced hyperphagia. Cell Rep43, 114343. 10.1016/j.celrep.2024.114343.
- Vossen, C., Schmidt, P., Wunderlich, C.M., Mittenbuhler, M.J., Tapken, C., Wienand, P., Mirabella, P.N., Cabot, L., Schumacher, A.L., Folz-Donahue, K., Kukat, C., Voigt, I., Bruning, J.C., Fenselau, H., and Wunderlich, F.T. (2024). An Approach to Intersectionally Target Mature Enteroendocrine Cells in the Small Intestine of Mice. Cells13. 10.3390/cells13010102.
- Zhou, X., Stine, C., Prada, P.O., Fusca, D., Assoumou, K., Dernic, J., Bhat, M.A., Achanta, A.S., Johnson, J.C., Pasqualini, A.L., Jadhav, S., Bauder, C.A., Steuernagel, L., Ravotto, L., Benke, D., Weber, B., Suko, A., Palmiter, R.D., Stoeber, M., Kloppenburg, P., Bruning, J.C., Bruchas, M.R., and Patriarchi, T. (2024). Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release. Nat Commun15, 5353. 10.1038/s41467-024-49712-0.
- Tadross, J.A., Steuernagel, L., Dowsett, G.K.C., Kentistou, K.A., Lundh, S., Porniece, M., Klemm, P., Rainbow, K., Hvid, H., Kania, K., Polex-Wolf, J., Knudsen, L.B., Pyke, C., Perry, J.R.B., Lam, B.Y.H., Bruning, J.C., and Yeo, G.S.H. (2025). A comprehensive spatio-cellular map of the human hypothalamus. Nature10.1038/s41586-024-08504-8. 10.1038/s41586-024-08504-8.
To top
Filipe Cabreiro
- Franco-Romero, A., Morbidoni, V., Milan, G., Sartori, R., Wulff, J., Romanello, V., Armani, A., Salviati, L., Conte, M., Salvioli, S., Franceschi, C., Buonomo, V., Swoboda, C.O., Grumati, P., Pannone, L., Martinelli, S., Jefferies, H.B., Dikic, I., van der Laan, J., Cabreiro, F., Millay, D.P., Tooze, S.A., Trevisson, E., and Sandri, M. (2024). C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals. J Clin Invest134. 10.1172/JCI165814.
- Said, M., Ferrara, B.T., Aprodu, A., Cabreiro, F., Thompson, E.P., and Everett, J. (2024). Transcriptional analysis of C. elegans fmos at different life stages and their roles in ageing. Mol Genet Genomics299, 113. 10.1007/s00438-024-02201-x.
- van der Laan, J., and Cabreiro, F. (2025). Microbes put drugs in(action). Trends Endocrinol Metab36, 7-10. 10.1016/j.tem.2024.08.005.
Oliver Cornely
- Bethe, U., Pana, Z.D., Drosten, C., Goossens, H., Konig, F., Marchant, A., Molenberghs, G., Posch, M., Van Damme, P., and Cornely, O.A. (2024). Innovative approaches for vaccine trials as a key component of pandemic preparedness - a white paper. Infection52, 2135-2144. 10.1007/s15010-024-02347-1.
- Byrne, J., Gu, L., Garcia-Leon, A., Gaillard, C.M., Saini, G., Alalwan, D., Tomas-Cortazar, J., Kenny, G., Donohue, S., Reynolds, B., O'Gorman, T., Landay, A., Doran, P., Stemler, J., Koehler, P., Cox, R.J., Olesen, O.F., Lelievre, J.D., O'Broin, C., Savinelli, S., Feeney, E.R., O'Halloran, J.A., Cotter, A., Horgan, M., Kelly, C., Sadlier, C., de Barra, E., Cornely, O.A., Gautier, V., and Mallon, P.W. (2024). Robust and persistent B-cell responses following SARS-CoV-2 vaccine determine protection from SARS-CoV-2 infection. Front Immunol15, 1445653. 10.3389/fimmu.2024.1445653.
- Clancy, C.J., Cornely, O.A., Marcella, S.W., Nguyen, S.T., Gozalo, L., and Cai, B. (2024). Effectiveness and Safety of Cefiderocol in Clinical Practice for Treatment of Patients with Gram-Negative Bacterial Infections: US Interim Results of the PROVE Study. Infect Drug Resist17, 4427-4443. 10.2147/IDR.S475462.
- Cornely, O.A., Thompson, G.I.I.I., Soriano, A., Kullberg, B.J., Kollef, M., Vazquez, J., Honore, P.M., Bassetti, M., Pullman, J., Dignani, C., Das, A.F., Sandison, T., and Pappas, P.G. (2024). Treatment outcomes with rezafungin and caspofungin in people aged 65 years and above with candidaemia and/or invasive candidiasis: integrated analysis of pooled Phase 2 and Phase 3 data. Jac-Antimicrob Resis6. 10.1093/jacamr/dlad143.033.
- de Hoog, S., Walsh, T.J., Ahmed, S.A., Alastruey-Izquierdo, A., Arendrup, M.C., Borman, A., Chen, S., Chowdhary, A., Colgrove, R.C., Cornely, O.A., Denning, D.W., Dufresne, P.J., Filkins, L., Gangneux, J.P., Gene, J., Groll, A.H., Guillot, J., Haase, G., Halliday, C., Hawksworth, D.L., Hay, R., Hoenigl, M., Hubka, V., Jagielski, T., Kandemir, H., Kidd, S.E., Kus, J.V., Kwon-Chung, J., Lockhart, S.R., Meis, J.F., Mendoza, L., Meyer, W., Nguyen, M.H., Song, Y., Sorrell, T.C., Stielow, J.B., Vilela, R., Vitale, R.G., Wengenack, N.L., White, P.L., Ostrosky-Zeichner, L., Zhang, S.X., and Fungi, I.E.F.W.G.N.o.C. (2024). Nomenclature for human and animal fungal pathogens and diseases: a proposal for standardized terminology. J Clin Microbiol62, e0093724. 10.1128/jcm.00937-24.
- Fernandes, R., Sabino, R., Cunha, C., Cornely, O.A., Carvalho, A., Salmanton-García, J., and Capacity, P.G.I.M. (2024). Multicentric Study on the Clinical Mycology Capacity and Access to Antifungal Treatment in Portugal. Mycopathologia189. 10.1007/s11046-024-00830-9.
- Honore, P.M., Girardis, M., Kollef, M., Cornely, O.A., Thompson, G.R., 3rd, Bassetti, M., Soriano, A., Huang, H., Vazquez, J., Kullberg, B.J., Pappas, P.G., Manamley, N., Sandison, T., Pullman, J., and Nseir, S. (2024). Rezafungin versus caspofungin for patients with candidaemia or invasive candidiasis in the intensive care unit: pooled analyses of the ReSTORE and STRIVE randomised trials. Crit Care28, 348. 10.1186/s13054-024-05117-5.
- Honore, P.M., Kollef, M., Thompson, G.I.I.I., Soriano, A., Cornely, O.A., Dignani, C., Manamley, N., Sandison, T., Pappas, P.G., Bassetti, M., and Investigators, R.T. (2024). Efficacy and safety of rezafungin in critically ill patients with candidaemia and/or IC: Outcomes of patients treated in the ICU from an integrated analysis of Phase 2 and Phase 3 trials. Jac-Antimicrob Resis6. 10.1093/jacamr/dlad143.034.
- Mellinghoff, S.C., Robrecht, S., Sprute, R., Mayer, L., Weskamm, L.M., Dahlke, C., Gruell, H., Teipel, F., Schloesser, H.A., Siepmann, K., Thelen, M., Fink, A.M., Fischer, K., Klein, F., Addo, M.M., Kolovou, A., Cornely, O.A., Eichhorst, B., Hallek, M., and Langerbeins, P. (2024). Hybrid immunity to SARS-CoV-2 in patients with chronic lymphocytic leukemia. Eur J Haematol10.1111/ejh.14170. 10.1111/ejh.14170.
- Neofytos, D., Pagliuca, A., Houghton, K., Broughton, E., de Figueiredo Valente, M.L.N., Jiang, L., Enoch, D.A., Gruener, B., Herbrecht, R., Lahmer, T., Lortholary, O., Melenotte, C., De Rosa, F.G., Garcia-Vidal, C., Jimenez, M., Fernandez, M., and Cornely, O. (2024). Effectiveness, Safety, and Patterns of Real-World Isavuconazole Use in Europe (2015-2019). Infect Dis Ther13, 2527-2543. 10.1007/s40121-024-01064-4.
- Ortiz, B., Varela, D., Fontecha, G., Torres, K., Cornely, O.A., and Salmanton-Garcia, J. (2024). Strengthening Fungal Infection Diagnosis and Treatment: An In-depth Analysis of Capabilities in Honduras. Open Forum Infect Dis11, ofae578. 10.1093/ofid/ofae578.
- Osaigbovo, I.I., Govender, N.P., Jordan, A.M., Bongomin, F., Meya, D.B., Kanyua, A., Mashedi, O.M., Koffi, D., Loyse, A., Sturny-Leclère, A., Gangneux, J.P., Denning, D.W., Chiller, T., Cornely, O.A., and Oladele, R.O. (2024). The Nairobi Declaration 2023: A commitment to address deadly yet neglected fungal diseases in Africa. Med Mycol62. 10.1093/mmy/myad141.
- Pantic, N., Barac, A., Mano, V., Dedeic-Ljubovic, A., Malkodanski, I., Jaksic, O., Gkentzi, D., Mitrovic, M., Munteanu, O., Sisevic, D., Stojanoski, Z., Popescu, O., Todorovic, J., Cornely, O.A., Salmanton-Garcia, J., and Collaborators (2024). Mapping the path to excellence: Evaluation of the diagnostic and treatment tools for invasive fungal infections in the balkans. J Infect Public Health17, 102493. 10.1016/j.jiph.2024.102493.
- Salmanton-Garcia, J., Cornely, O.A., Stemler, J., Barac, A., Steinmann, J., Sivakova, A., Akalin, E.H., Arikan-Akdagli, S., Loughlin, L., Toscano, C., Narayanan, M., Rogers, B., Willinger, B., Akyol, D., Roilides, E., Lagrou, K., Mikulska, M., Denis, B., Ponscarme, D., Scharmann, U., Azap, A., Lockhart, D., Bicanic, T., Kron, F., Erben, N., Rautemaa-Richardson, R., Goodman, A.L., Garcia-Vidal, C., Lass-Florl, C., Gangneux, J.P., Taramasso, L., Ruiz, M., Schick, Y., Van Wijngaerden, E., Milacek, C., Giacobbe, D.R., Logan, C., Rooney, E., Gori, A., Akova, M., Bassetti, M., Hoenigl, M., and Koehler, P. (2024). Attributable mortality of candidemia - Results from the ECMM Candida III multinational European Observational Cohort Study. J Infect89, 106229. 10.1016/j.jinf.2024.106229.
- Sehgal, I.S., Muthu, V., Seidel, D., Sprute, R., Armstrong-James, D., Asano, K., Chalmers, J.D., Gangneux, J.P., Godet, C., Salzer, H.J.F., Cornely, O.A., and Agarwal, R. (2024). EQUAL ABPA Score 2024: A Tool to Measure Guideline Adherence for Managing Allergic Bronchopulmonary Aspergillosis. Mycoses67, e13810. 10.1111/myc.13810.
- Soriano, A., Honore, P.M., Cornely, O.A., Chayakulkeeree, M., Bassetti, M., Haihui, H., Dupont, H., Kim, Y.K., Kollef, M., Kullberg, B.J., Manamley, N., Pappas, P., Pullman, J., Sandison, T., Dignani, C., Vazquez, J.A., and Thompson, G.R., 3rd (2024). Treatment Outcomes Among Patients With a Positive Candida Culture Close to Randomization Receiving Rezafungin or Caspofungin in the ReSTORE Study. Clin Infect Dis79, 672-681. 10.1093/cid/ciae363.
- Sprute, R., and Cornely, O.A. (2024). Lessons learnt from conducting a randomised clinical trial in eumycetoma. Lancet Infect Dis24, 1186-1187. 10.1016/S1473-3099(24)00451-1.
- Stemler, J., Gavriilaki, E., Hlukhareva, O., Khanna, N., Neofytos, D., Akova, M., Pagano, L., Cisneros, J.M., Cornely, O.A., and Salmanton-Garcia, J. (2024). Current practice of screening and antimicrobial prophylaxis to prevent Gram-negative bacterial infection in high-risk haematology patients: results from a pan-European survey. Ther Adv Infect Dis11, 20499361241271863. 10.1177/20499361241271863.
- Stemler, J., Yeghiazaryan, L., Stephan, C., Mohn, K.G., Carcas-Sansuan, A.J., Rodriguez, E.R., Molto, J., Mitxeltorena, I.V., Welte, T., Zablockiene, B., Akova, M., Bethe, U., Heringer, S., Salmanton-Garcia, J., Jeck, J., Tischmann, L., Zarrouk, M., Cuppers, A., Biehl, L.M., Grothe, J., Mellinghoff, S.C., Nacov, J.A., Neuhann, J.M., Sprute, R., Frias-Iniesta, J., Negi, R., Gaillard, C., Saini, G., Leon, A.G., Mallon, P.W.G., Lammens, C., Hotterbeekx, A., Loens, K., Malhotra-Kumar, S., Goossens, H., Kumar-Singh, S., Konig, F., Posch, M., Koehler, P., Cornely, O.A., and consortium, E.-C.-A.s.g.o.b.o.t.V. (2024). Immunogenicity, reactogenicity, and safety of a second booster with BNT162b2 or full-dose mRNA-1273: A randomized VACCELERATE trial in adults aged >/=75 years (EU-COVAT-1-AGED Part B). Int J Infect Dis146, 107161. 10.1016/j.ijid.2024.107161.
- Vena, A., Bassetti, M., Mezzogori, L., Marchesi, F., Hoenigl, M., Giacobbe, D.R., Corcione, S., Bartoletti, M., Stemler, J., Pagano, L., Cornely, O.A., and Salmanton-García, J. (2024). Laboratory and clinical management capacity for invasive fungal infections: the Italian landscape. Infection52, 197-208. 10.1007/s15010-023-02084-x.
- Wiesen, M.H.J., Stemler, J., Fietz, C., Joisten, C., Cornely, O.A., Verougstraete, N., Streichert, T., and Müller, C. (2024). Quantification of midostaurin in plasma and serum by stable isotope dilution liquid chromatography-tandem mass spectrometry: Application to a cohort of patients with acute myeloid leukemia. Eur J Haematol10.1111/ejh.14178. 10.1111/ejh.14178.
- Wingen-Heimann, S.M., Cornely, O.A., Seidel, D., and Salmanton-Garcia, J. (2024). Costs for global guideline-based diagnosis of mucormycosis in patients with neutropenia, hematopoietic stem cell or solid organ transplantation - a perspective of the German healthcare system. Expert Rev Pharmacoecon Outcomes Res10.1080/14737167.2024.2426613. 10.1080/14737167.2024.2426613.
- Wolfgruber, S., Sedik, S., Klingspor, L., Tortorano, A., Gow, N.A.R., Lagrou, K., Gangneux, J.P., Maertens, J., Meis, J.F., Lass-Florl, C., Arikan-Akdagli, S., Cornely, O.A., and Hoenigl, M. (2024). Insights from Three Pan-European Multicentre Studies on Invasive Candida Infections and Outlook to ECMM Candida IV. Mycopathologia189, 70. 10.1007/s11046-024-00871-0.
- Bekaan, N., Cornely, O.A., Friede, T., Prattes, J., Sprute, R., Hellmich, M., Koehler, P., Salmanton-Garcia, J., Stemler, J., and Reinhold, I. (2025). Which trial do we need? Shorter antifungal treatment for candidemia - challenging the 14-day dogma. Clin Microbiol Infect31, 147-151. 10.1016/j.cmi.2024.09.004.
Mauro Corrado
- Cosgrove, J., Marcais, A., Hartmann, F.J., Bergthaler, A., Zanoni, I., Corrado, M., Perie, L., Cabezas-Wallscheid, N., Bousso, P., Alexandrov, T., Kielian, T., Martinez-Martin, N., Opitz, C.A., Lyssiotis, C.A., Arguello, R.J., and Van den Bossche, J. (2024). A call for accessible tools to unlock single-cell immunometabolism research. Nat Metab6, 779-782. 10.1038/s42255-024-01031-w.
- Garcia, B.M., Melchinger, P., Medeiros, T., Hendrix, S., Prabhu, K., Corrado, M., Kingma, J., Gorbatenko, A., Deshwal, S., Veronese, M., Scorrano, L., Pearce, E., Giavalisco, P., Zelcer, N., and Pernas, L. (2024). Glutamine sensing licenses cholesterol synthesis. EMBO J43, 5837-5856. 10.1038/s44318-024-00269-0.
- Villa, M., Sanin, D.E., Apostolova, P., Corrado, M., Kabat, A.M., Cristinzio, C., Regina, A., Carrizo, G.E., Rana, N., Stanczak, M.A., Baixauli, F., Grzes, K.M., Cupovic, J., Solagna, F., Hackl, A., Globig, A.M., Hassler, F., Puleston, D.J., Kelly, B., Cabezas-Wallscheid, N., Hasselblatt, P., Bengsch, B., Zeiser, R., Sagar, Buescher, J.M., Pearce, E.J., and Pearce, E.L. (2024). Prostaglandin E(2) controls the metabolic adaptation of T cells to the intestinal microenvironment. Nat Commun15, 451. 10.1038/s41467-024-44689-2.
Claus Cursiefen
- Ader, M., Cursiefen, C., Fauser, S., Gliem, M., Helbig, H., Lagreze, W., Marshall, J., Roesky, C., Sahel, J.A., Schlotzer-Schrehard, U., Sieving, P., and Ueffing, M. (2024). [Ophthalmological research in Germany: evaluation by an international expert panel]. Ophthalmologie121, 482-486. 10.1007/s00347-024-02043-3.
- Calzetti, G., Schwarzwalder, K., Ottonelli, G., Kaminska, K., Strauss, R.W., Baere, E., Leroy, B.P., Audo, I., Zeitz, C., Cursiefen, C., Stingl, K., Boon, C.J.F., Marques, J.P., Santos, C., Ayuso Garcia, C., Escher, P., Cordeiro, M.F., D'Esposito, F., Charbel Issa, P., Lotery, A., Lin, S., Michaelides, M., Rivolta, C., and Scholl, H.P.N. (2024). Genetic Testing of Patients with Inherited Retinal Diseases in the European Countries: An International Survey by the European Vision Institute. Ophthalmic Res67, 448-457. 10.1159/000540607.
- Gietzelt, C., Koenig, L., Adler, W., Schaub, F., Heindl, L.M., Cursiefen, C., Dietlein, T.S., and Enders, P. (2024). A comparative study of cystoid macula edema following glaucoma drainage device surgery versus trabeculectomy. Int Ophthalmol44, 150. 10.1007/s10792-024-03068-y.
- Hadrian, K., and Cursiefen, C. (2024). The role of lymphatic vessels in corneal fluid homeostasis and wound healing. J Ophthalmic Inflamm Infect14, 4. 10.1186/s12348-023-00381-y.
- Hamdorf, M., Imhof, T., Bailey-Elkin, B., Betz, J., Theobald, S.J., Simonis, A., Di Cristanziano, V., Gieselmann, L., Dewald, F., Lehmann, C., Augustin, M., Klein, F., Alejandre Alcazar, M.A., Rongisch, R., Fabri, M., Rybniker, J., Goebel, H., Stetefeld, J., Brachvogel, B., Cursiefen, C., Koch, M., and Bock, F. (2024). The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm. J Mol Cell Biol15. 10.1093/jmcb/mjad062.
- Hopkinson, A., Notara, M., Cursiefen, C., and Sidney, L.E. (2024). Increased Anti-Inflammatory Therapeutic Potential and Progenitor Marker Expression of Corneal Mesenchymal Stem Cells Cultured in an Optimized Propagation Medium. Cell Transplant33, 9636897241241992. 10.1177/09636897241241992.
- Hou, Y., Zhang, W., Le, V.N.H., Deng, S., Hadrian, K., Mestanoglu, M., Musial, G., Bock, F., and Cursiefen, C. (2024). Efficacy and safety of combined UV-light corneal crosslinking and fine-needle diathermy to regress pathological murine corneal (lymph)angiogenesis in vivo. Acta Ophthalmol102, e1002-e1010. 10.1111/aos.16696.
- Howaldt, A., Lenglez, S., Velmans, C., Schultheis, A.M., Clahsen, T., Matthaei, M., Kohlhase, J., Vokuhl, C., Buttner, R., Netzer, C., Demoulin, J.B., and Cursiefen, C. (2024). Corneal Infantile Myofibromatosis Caused by Novel Activating Imatinib-Responsive Variants in PDGFRB. Ophthalmol Sci4, 100444. 10.1016/j.xops.2023.100444.
- Howaldt, A., Zhang, W., Deng, S., Becker, M., Hou, Y., Clahsen, T., Bock, F., and Cursiefen, C. (2024). Corneal crosslinking ameliorates the extent of corneal oedema in subsequent acute keratoconus in an ex vivo model. Acta Ophthalmol102, e134-e137. 10.1111/aos.15712.
- Peil, J., Vossen, C., Bock, F., Clahsen, T., Schiller, P., Heindl, L.M., Bosch, J.J., Wunderlich, F.T., Cursiefen, C., and Schlereth, S.L. (2024). Combined Osteopontin Blockade and Type 2 Classical Dendritic Cell Vaccination as Effective Synergetic Therapy for Conjunctival Melanoma. J Immunol212, 487-499. 10.4049/jimmunol.2300063.
- Schoneberger, V., Tahmaz, V., Matthaei, M., Roters, S., Schlereth, S.L., Schaub, F., Cursiefen, C., and Bachmann, B.O. (2024). Allogeneic limbo-deep anterior lamellar keratoplasty (Limbo-DALK)-A novel surgical technique in corneal stromal disease and limbal stem cell deficiency. Plos One19, e0298241. 10.1371/journal.pone.0298241.
- Schrittenlocher, S., Weliwitage, J., Matthaei, M., Bachmann, B., and Cursiefen, C. (2024). Influence of Donor Factors on Descemet Membrane Endothelial Keratoplasty (DMEK) Graft Preparation Outcome. Clin Ophthalmol18, 793-797. 10.2147/OPTH.S448912.
- van Velthoven, A.J.H., Utheim, T.P., Notara, M., Bremond-Gignac, D., Figueiredo, F.C., Skottman, H., Aberdam, D., Daniels, J.T., Ferrari, G., Grupcheva, C., Koppen, C., Parekh, M., Ritter, T., Romano, V., Ferrari, S., Cursiefen, C., Lagali, N., LaPointe, V.L.S., and Dickman, M.M. (2024). Corrigendum to "Future directions in managing aniridia-associated keratopathy" [Surv Ophthalmol 68 (2023) 940-956]. Surv Ophthalmol69, 300-301. 10.1016/j.survophthal.2024.01.001.
- Vernin, A., Schrittenlocher, S., Matthaei, M., Roters, S., Siebelmann, S., Bachmann, B., Schiller, P., Cursiefen, C., and Schlereth, S.L. (2024). Excimer Laser Phototherapeutic Keratectomy for Anterior Corneal Opacification After Descemet Membrane Endothelial Keratoplasty. Cornea43, 95-104. 10.1097/ICO.0000000000003396.
- Volatier, T., Cursiefen, C., and Notara, M. (2024). Current Advances in Corneal Stromal Stem Cell Biology and Therapeutic Applications. Cells13. 10.3390/cells13020163.
- Wiedemann, J., Hos, D., Limburg, E., Zettelmeyer, U., Schiller, P., Franklin, J., Bachmann, B., Bohringer, D., Dietrich-Ntoukas, T., Fuchsluger, T.A., Geerling, G., Lang, S.J., Mayer, W.J., Priglinger, S., Reinhard, T., Seitz, B., and Cursiefen, C. (2024). UV light-mediated corneal crosslinking as (lymph)angioregressive pretreatment to promote graft survival after subsequent high-risk corneal transplantation (CrossCornealVision): protocol for a multicenter, randomized controlled trial. Trials25, 169. 10.1186/s13063-024-08011-1.
- Ader, M., Cursiefen, C., Fauser, S., Gliem, M., Helbig, H., Lagreze, W., Marshall, J., Roesky, C., Sahel, J.A., Schlotzer-Schrehard, U., Sieving, P., and Ueffing, M. (2025). Ophthalmological research in Germany: suggestions by an international expert panel. Ophthalmologie122, 29-33. 10.1007/s00347-024-02048-y.
- Schoneberger, V., Tahmaz, V., Menghesha, L., Luke, J.N., Cursiefen, C., Schaub, F., and Bachmann, B.O. (2025). Retinal Detachment Rates After Uncomplicated DMEK Versus Cataract Surgery Combined (Triple-)DMEK. Cornea44, 203-208. 10.1097/ICO.0000000000003554.
Joris Deelen
- Baghdadi, M., Nespital, T., Monzo, C., Deelen, J., Gronke, S., and Partridge, L. (2024). Intermittent rapamycin feeding recapitulates some effects of continuous treatment while maintaining lifespan extension. Mol Metab10.1016/j.molmet.2024.101902, 101902. 10.1016/j.molmet.2024.101902.
- Bizzarri, D., Reinders, M.J.T., Kuiper, L., Beekman, M., Deelen, J., van Meurs, J.B.J., van Dongen, J., Pool, R., Boomsma, D.I., Ghanbari, M., Franke, L., Consortium, B., Slagboom, P.E., and van den Akker, E.B. (2024). NMR metabolomics-guided DNA methylation mortality predictors. Ebiomedicine107, 105279. 10.1016/j.ebiom.2024.105279.
- Gladyshev, V.N., Anderson, B., Barlit, H., Barre, B., Beck, S., Behrouz, B., Belsky, D.W., Chaix, A., Chamoli, M., Chen, B.H., Cheng, K., Chuprin, J., Churchill, G.A., Cipriano, A., Colville, A., Deelen, J., Deigin, Y., Edmonds, K.K., English, B.W., Fang, R., Florea, M., Gershteyn, I.M., Gill, D., Goetz, L.H., Gorbunova, V., Griffin, P.T., Horvath, S., Borch Jensen, M., Jin, X., Jovanovska, S., Kajderowicz, K.M., Kasahara, T., Kerepesi, C., Kulkarni, S., Labunskyy, V.M., Levine, M.E., Libert, S., Lu, J.Y., Lu, Y.R., Marioni, R.E., McCoy, B.M., Mitchell, W., Moqri, M., Nasirian, F., Niimi, P., Oh, H.S., Okundaye, B., Parkhitko, A.A., Peshkin, L., Petljak, M., Poganik, J.R., Pridham, G., Promislow, D.E.L., Prusisz, W., Quiniou, M., Raj, K., Richard, D., Ricon, J.L., Rutledge, J., Scheibye-Knudsen, M., Schork, N.J., Seluanov, A., Shadpour, M., Shindyapina, A.V., Shuken, S.R., Sivakumar, S., Stoeger, T., Sugiura, A., Sutton, N.R., Suvorov, A., Tarkhov, A.E., Teeling, E.C., Trapp, A., Tyshkovskiy, A., Unfried, M., Ward-Caviness, C.K., Yim, S.H., Ying, K., Yunes, J., Zhang, B., and Zhavoronkov, A. (2024). Disagreement on foundational principles of biological aging. PNAS Nexus3, pgae499. 10.1093/pnasnexus/pgae499.
- Jia, X., Fan, J., Wu, X., Cao, X., Ma, L., Abdelrahman, Z., Zhao, F., Zhu, H., Bizzarri, D., Akker, E., Slagboom, P.E., Deelen, J., Zhou, D., and Liu, Z. (2024). A Novel Metabolomic Aging Clock Predicting Health Outcomes and Its Genetic and Modifiable Factors. Adv Sci (Weinh)11, e2406670. 10.1002/advs.202406670.
- Pickert, L., Dias, I.H.K., Thimm, A., Weber, J., Abdullah, S., Deelen, J., and Polidori, M.C. (2024). Micronutrients, Frailty, and Cognitive Impairment: Design and Preliminary Results from the CogLife 2.0 Study. J Alzheimers Dis100, S251-S263. 10.3233/JAD-240654.
- Setinc, M., Celinscak, Z., Bockor, L., Zajc Petranovic, M., Stojanovic Markovic, A., Pericic Salihovic, M., Deelen, J., and Skaric-Juric, T. (2024). The role of longevity-related genetic variant interactions as predictors of survival after 85 years of age. Mech Ageing Dev219, 111926. 10.1016/j.mad.2024.111926.
- Sittig, J., Pickert, L., Weigert, H., Deelen, J., Polidori, M.C., and Nelles, G. (2024). Relationship Between Endothelial Function, Vital Parameters, and Cognitive Performance in Community Dwellers with Subjective Cognitive Decline: An Observational Study with Six Months Follow Up. J Alzheimers Dis100, S13-S24. 10.3233/JAD-240661.
- Smulders, L., and Deelen, J. (2024). Genetics of human longevity: From variants to genes to pathways. J Intern Med295, 416-435. 10.1111/joim.13740.
- van Holstein, Y., Mooijaart, S.P., van Oevelen, M., van Deudekom, F.J., Vojinovic, D., Bizzarri, D., van den Akker, E.B., Noordam, R., Deelen, J., van Heemst, D., de Glas, N.A., Holterhues, C., Labots, G., van den Bos, F., Beekman, M., Slagboom, P.E., van Munster, B.C., Portielje, J.E.A., and Trompet, S. (2024). The performance of metabolomics-based prediction scores for mortality in older patients with solid tumors. Geroscience46, 5615-5627. 10.1007/s11357-024-01261-6.
Constantinos Demetriades
- Acharya, A., and Demetriades, C. (2024). mTORC1 activity licenses its own release from the lysosomal surface. Mol Cell84, 4385-4400 e4387. 10.1016/j.molcel.2024.10.008.
- Fernandes, S.A., Angelidaki, D.D., Nuchel, J., Pan, J., Gollwitzer, P., Elkis, Y., Artoni, F., Wilhelm, S., Kovacevic-Sarmiento, M., and Demetriades, C. (2024). Spatial and functional separation of mTORC1 signalling in response to different amino acid sources. Nat Cell Biol26, 1918-1933. 10.1038/s41556-024-01523-7.
- Perri, G., French, C., Agostinis-Sobrinho, C., Anand, A., Antarianto, R.D., Arai, Y., Baur, J.A., Cauli, O., Clivaz-Duc, M., Colloca, G., Demetriades, C., de Lucia, C., Di Gessa, G., Diniz, B.S., Dotchin, C.L., Eaglestone, G., Elliott, B.T., Espeland, M.A., Ferrucci, L., Fisher, J., Grammatopoulos, D.K., Hardiany, N.S., Hassan-Smith, Z., Hastings, W.J., Jain, S., Joshi, P.K., Katsila, T., Kemp, G.J., Khaiyat, O.A., Lamming, D.W., Gallegos, J.L., Madeo, F., Maier, A.B., Martin-Ruiz, C., Martins, I.J., Mathers, J.C., Mattin, L.R., Merchant, R.A., Moskalev, A., Neytchev, O., Ni Lochlainn, M., Owen, C.M., Phillips, S.M., Pratt, J., Prokopidis, K., Rattray, N.J.W., Rua-Alonso, M., Schomburg, L., Scott, D., Shyam, S., Sillanpaa, E., Tan, M.M.C., Teh, R., Tobin, S.W., Vila-Cha, C.J., Vorluni, L., Weber, D., Welch, A., Wilson, D., Wilson, T., Zhao, T., Philippou, E., Korolchuk, V.I., and Shannon, O.M. (2024). An expert consensus statement on biomarkers of ageing for use in intervention studies. J Gerontol A Biol Sci Med Sci10.1093/gerona/glae297. 10.1093/gerona/glae297.
Sabine Eming
- Injarabian, L., Willenborg, S., Welcker, D., Sanin, D.E., Pasparakis, M., Kashkar, H., and Eming, S.A. (2024). FADD- and RIPK3-Mediated Cell Death Ensures Clearance of Ly6C(high) Wound Macrophages from Damaged Tissue. J Invest Dermatol144, 152-164 e157. 10.1016/j.jid.2023.06.203.
- Mammadov, Y., Austin, J., Shipowick, T., Veldman, K., Eming, S., Szegedi, A., Sprecher, E., and Conrad, C. (2024). A European Roundtable "Addressing Under-Prioritized Skin Diseases: Policy Responses to High-Burden Conditions". J Invest Dermatol144, 2631-2633. 10.1016/j.jid.2024.05.019.
- Reiter, L., Niehoff, N., Weiland, D., Helbig, D., Eming, S.A., Krieg, T., Etich, J., Brachvogel, B., Wiesner, R.J., and Knuever, J. (2024). Mitochondrial DNA mutations attenuate Bleomycin-induced dermal fibrosis by inhibiting differentiation into myofibroblasts. Matrix Biol132, 72-86. 10.1016/j.matbio.2024.07.002.
- Willenborg, S., Satzinger, S., and Eming, S.A. (2024). [Skin fibrosis : Novel insights in pathophysiology and treatment]. Dermatologie (Heidelb)75, 218-224. 10.1007/s00105-024-05299-7.
Henning Fenselau
- Borgmann, D., and Fenselau, H. (2024). Vagal pathways for systemic regulation of glucose metabolism. Semin Cell Dev Biol156, 244-252. 10.1016/j.semcdb.2023.07.010.
- Dodt, S., Widdershooven, N.V., Dreisow, M.L., Weiher, L., Steuernagel, L., Wunderlich, F.T., Bruning, J.C., and Fenselau, H. (2024). NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation. Nat Commun15, 5439. 10.1038/s41467-024-49766-0.
- Engstrom Ruud, L., Font-Girones, F., Zajdel, J., Kern, L., Teixidor-Deulofeu, J., Manneras-Holm, L., Carreras, A., Becattini, B., Bjorefeldt, A., Hanse, E., Fenselau, H., Solinas, G., Bruning, J.C., Wunderlich, T.F., Backhed, F., and Ruud, J. (2024). Activation of GFRAL(+) neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor. Cell Rep43, 113960. 10.1016/j.celrep.2024.113960.
- Ruud, L.E., Font-Girones, F., Zajdel, J., Kern, L., Teixidor-Deulofeu, J., Manneräs-Holm, L., Carreras, A., Becattini, B., Björefeldt, A., Hanse, E., Fenselau, H., Solinas, G., Bruening, J.C., Wunderlich, T.F., Backhed, F., and Ruud, J. (2024). Activation of GFRAL plus neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor. Cell Rep43. 10.1016/j.celrep.2024.113960.
- Sotelo-Hitschfeld, T., Minere, M., Klemm, P., Borgmann, D., Wnuk-Lipinski, D., Jais, A., Jia, X., Corneliussen, S., Kloppenburg, P., Fenselau, H., and Bruning, J.C. (2024). GABAergic disinhibition from the BNST to PNOC(ARC) neurons promotes HFD-induced hyperphagia. Cell Rep43, 114343. 10.1016/j.celrep.2024.114343.
- Vossen, C., Schmidt, P., Wunderlich, C.M., Mittenbuhler, M.J., Tapken, C., Wienand, P., Mirabella, P.N., Cabot, L., Schumacher, A.L., Folz-Donahue, K., Kukat, C., Voigt, I., Bruning, J.C., Fenselau, H., and Wunderlich, F.T. (2024). An Approach to Intersectionally Target Mature Enteroendocrine Cells in the Small Intestine of Mice. Cells13. 10.3390/cells13010102.
To top
Dietmar Fischer
- Gobrecht, P., Gebel, J., Hilla, A., Gisselmann, G., and Fischer, D. (2024). Targeting Vasohibins to Promote Axon Regeneration. J Neurosci44. 10.1523/JNEUROSCI.2031-23.2024.
- Gobrecht, P., Gebel, J., Leibinger, M., Zeitler, C., Chen, Z., Grundemann, D., and Fischer, D. (2024). Cnicin promotes functional nerve regeneration. Phytomedicine129, 155641. 10.1016/j.phymed.2024.155641.
- Lu, S., Stone, J.E., Klerman, E.B., McHill, A.W., Barger, L.K., Robbins, R., Fischer, D., Sano, A., Czeisler, C.A., Rajaratnam, S.M.W., and Phillips, A.J.K. (2024). The organization of sleep-wake patterns around daily schedules in college students. Sleep47. 10.1093/sleep/zsad278.
- Pepanian, A., Sommerfeld, P., Binbay, F.A., Fischer, D., Pietsch, M., and Imhof, D. (2024). In-depth analysis of Galphas protein activity by probing different fluorescently labeled guanine nucleotides. Biol Chem405, 297-309. 10.1515/hsz-2023-0321.
- Renk, P., Sgodzai, M., Klimas, R., Blusch, A., Gruter, T., Motte, J., Pedreiturria, X., Gebel, J., Gobrecht, P., Fischer, D., Gold, R., and Pitarokoili, K. (2024). Small fibre integrity and axonal pathology in the rat model of experimental autoimmune neuritis. Brain Commun6, fcae059. 10.1093/braincomms/fcae059.
- Smagula, S.F., Zhang, G., Krafty, R.T., Ramos, A., Sotres-Alvarez, D., Rodakowski, J., Gallo, L.C., Lamar, M., Gujral, S., Fischer, D., Tarraf, W., Mossavar-Rahmani, Y., Redline, S., Stone, K.L., Gonzalez, H.M., and Patel, S.R. (2024). Sleep-wake behaviors associated with cognitive performance in middle-aged participants of the Hispanic Community Health Study/Study of Latinos. Sleep Health10, 500-507. 10.1016/j.sleh.2024.02.002.
- Zeitler, C., Leibinger, M., and Fischer, D. (2024). Inhibition of tubulin detyrosination: a novel strategy to promote central nervous system regeneration. Neural Regen Res19, 2557-2558. 10.4103/NRR.NRR-D-23-02015.
- Fischer, D., Weigand, M.A., Moss, R., Veiras, S., Kubel, B., Garcia-Erce, J.A., Zacharowski, K., Meybohm, P., Waters, J.H., Raasveld, S.J., Vlaar, A.P.J., Richards, T., Meier, J., Lasocki, S., Hofmann, A., Shander, A., von Heymann, C., Dietrich, G., Fries, D., Steinbicker, A.U., Rondinelli, M.B., Levy, J.H., Beck, G., and Frietsch, T. (2025). Incorporating the concept of overtransfusion into hemovigilance monitoring: An expert-based definition and criteria from the International HIT-OVER Forum. Transfusion65, 110-121. 10.1111/trf.17973.
To top
Lukas P. Frenzel
- Richardson, T., Scheid, C., Herling, M., Frenzel, L.P., Herling, C., Aguilar, M.R.C., Theurich, S., Hallek, M., and Holtick, U. (2024). Post-transplant-cyclophosphamide and short-term Everolimus as graft-versus-host-prophylaxis in patients with relapsed/refractory lymphoma and myeloma-Final results of the phase II OCTET-EVER trial. Eur J Haematol113, 163-171. 10.1111/ejh.14210.
- Stark, K., Kilani, B., Stockhausen, S., Busse, J., Schubert, I., Tran, T.D., Gaertner, F., Leunig, A., Pekayvaz, K., Nicolai, L., Fumagalli, V., Stermann, J., Stephan, F., David, C., Muller, M.B., Heyman, B., Lux, A., da Palma Guerreiro, A., Frenzel, L.P., Schmidt, C.Q., Dopler, A., Moser, M., Chandraratne, S., von Bruhl, M.L., Lorenz, M., Korff, T., Rudelius, M., Popp, O., Kirchner, M., Mertins, P., Nimmerjahn, F., Iannacone, M., Sperandio, M., Engelmann, B., Verschoor, A., and Massberg, S. (2024). Antibodies and complement are key drivers of thrombosis. Immunity57, 2140-2156 e2110. 10.1016/j.immuni.2024.08.007.
- Richardson, T., Tharmaseelan, H., Frenzel, L., Godel, P., Furstenau, M., Nieper, P., Braun, T., Schutte, D., Hallek, M., Scheid, C., and Holtick, U. (2025). Post-transplant-cyclophosphamide plus everolimus as GvHD prophylaxis in refractory T- and B-cell lymphoma. Bone Marrow Transplant60, 244-246. 10.1038/s41409-024-02472-3.
To top
Christian Frezza
- Badja, C., Momen, S., Koh, G.C.C., Boushaki, S., Roumeliotis, T.I., Kozik, Z., Jones, I., Bousgouni, V., Dias, J.M.L., Krokidis, M.G., Young, J., Chen, H., Yang, M., Docquier, F., Memari, Y., Valcarcel-Zimenez, L., Gupta, K., Kong, L.R., Fawcett, H., Robert, F., Zhao, S., Degasperi, A., Kumar, Y., Davies, H., Harris, R., Frezza, C., Chatgilialoglu, C., Sarkany, R., Lehmann, A., Bakal, C., Choudhary, J., Fassihi, H., and Nik-Zainal, S. (2024). Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system. Cell Rep43, 114243. 10.1016/j.celrep.2024.114243.
- Clerici, S., Podrini, C., Stefanoni, D., Distefano, G., Cassina, L., Steidl, M.E., Tronci, L., Canu, T., Chiaravalli, M., Spies, D., Bell, T.A., 3rd, Costa, A.S., Esposito, A., D'Alessandro, A., Frezza, C., Bachi, A., and Boletta, A. (2024). Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression. EMBO Mol Med16, 1379-1403. 10.1038/s44321-024-00071-9.
- Frezza, C. (2024). Fructose: the sweet(er) side of the Warburg effect. Cell Death Differ31, 1395-1397. 10.1038/s41418-024-01395-2.
- Guberovic, I., and Frezza, C. (2024). Functional implications of fumarate-induced cysteine succination. Trends Biochem Sci49, 775-790. 10.1016/j.tibs.2024.05.003.
- Haase, L., and Frezza, C. (2024). Itaconate promotes an unexpected tumor immune escape mechanism. Cancer Cell42, 1988-1990. 10.1016/j.ccell.2024.10.011.
- Herms, A., Colom, B., Piedrafita, G., Kalogeropoulou, A., Banerjee, U., King, C., Abby, E., Murai, K., Caseda, I., Fernandez-Antoran, D., Ong, S.H., Hall, M.W.J., Bryant, C., Sood, R.K., Fowler, J.C., Pol, A., Frezza, C., Vanhaesebroeck, B., and Jones, P.H. (2024). Organismal metabolism regulates the expansion of oncogenic PIK3CA mutant clones in normal esophagus. Nat Genet56, 2144-2157. 10.1038/s41588-024-01891-8.
- Ionescu, R.B., Nicaise, A.M., Reisz, J.A., Williams, E.C., Prasad, P., Willis, C.M., Simoes-Abade, M.B.C., Sbarro, L., Dzieciatkowska, M., Stephenson, D., Suarez Cubero, M., Rizzi, S., Pirvan, L., Peruzzotti-Jametti, L., Fossati, V., Edenhofer, F., Leonardi, T., Frezza, C., Mohorianu, I., D'Alessandro, A., and Pluchino, S. (2024). Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis. Cell Stem Cell31, 1574-1590 e1511. 10.1016/j.stem.2024.09.014.
- Kamp, M., Surmacki, J., Segarra Mondejar, M., Young, T., Chrabaszcz, K., Joud, F., Zecchini, V., Speed, A., Frezza, C., and Bohndiek, S.E. (2024). Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues. Nat Commun15, 5386. 10.1038/s41467-024-49403-w.
- Kong, L.R., Gupta, K., Wu, A.J., Perera, D., Ivanyi-Nagy, R., Ahmed, S.M., Tan, T.Z., Tan, S.L., Fuddin, A., Sundaramoorthy, E., Goh, G.S., Wong, R.T.X., Costa, A.S.H., Oddy, C., Wong, H., Patro, C.P.K., Kho, Y.S., Huang, X.Z., Choo, J., Shehata, M., Lee, S.C., Goh, B.C., Frezza, C., Pitt, J.J., and Venkitaraman, A.R. (2024). A glycolytic metabolite bypasses "two-hit" tumor suppression by BRCA2. Cell187, 2269-2287 e2216. 10.1016/j.cell.2024.03.006.
- Meiser, J., and Frezza, C. (2024). Presenting metabolomics analyses: what's in a number? EMBO J43, 4444-4450. 10.1038/s44318-024-00098-1.
- Mora, A., Schmidt, C., Balderson, B., Frezza, C., and Boden, M. (2024). SiRCle (Signature Regulatory Clustering) model integration reveals mechanisms of phenotype regulation in renal cancer. Genome Med16, 144. 10.1186/s13073-024-01415-3.
- Moschandrea, C., Kondylis, V., Evangelakos, I., Herholz, M., Schneider, F., Schmidt, C., Yang, M., Ehret, S., Heine, M., Jaeckstein, M.Y., Szczepanowska, K., Schwarzer, R., Baumann, L., Bock, T., Nikitopoulou, E., Brodesser, S., Kruger, M., Frezza, C., Heeren, J., Trifunovic, A., and Pasparakis, M. (2024). Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes. Nature625, 385-392. 10.1038/s41586-023-06857-0.
- Peruzzotti-Jametti, L., Willis, C.M., Krzak, G., Hamel, R., Pirvan, L., Ionescu, R.B., Reisz, J.A., Prag, H.A., Garcia-Segura, M.E., Wu, V., Xiang, Y., Barlas, B., Casey, A.M., van den Bosch, A.M.R., Nicaise, A.M., Roth, L., Bates, G.R., Huang, H., Prasad, P., Vincent, A.E., Frezza, C., Viscomi, C., Balmus, G., Takats, Z., Marioni, J.C., D'Alessandro, A., Murphy, M.P., Mohorianu, I., and Pluchino, S. (2024). Mitochondrial complex I activity in microglia sustains neuroinflammation. Nature628, 195-203. 10.1038/s41586-024-07167-9.
- Popovic, M., Isermann, L., Geissen, S., Senft, K., Georgomanolis, T., Baldus, S., Frezza, C., and Trifunovic, A. (2024). Tissue-specific adaptations to cytochrome c oxidase deficiency shape physiological outcomes. Biochim Biophys Acta Mol Basis Dis1871, 167567. 10.1016/j.bbadis.2024.167567.
- Tan, J., Virtue, S., Norris, D.M., Conway, O.J., Yang, M., Bidault, G., Gribben, C., Lugtu, F., Kamzolas, I., Krycer, J.R., Mills, R.J., Liang, L., Pereira, C., Dale, M., Shun-Shion, A.S., Baird, H.J., Horscroft, J.A., Sowton, A.P., Ma, M., Carobbio, S., Petsalaki, E., Murray, A.J., Gershlick, D.C., Nathan, J.A., Hudson, J.E., Vallier, L., Fisher-Wellman, K.H., Frezza, C., Vidal-Puig, A., and Fazakerley, D.J. (2024). Limited oxygen in standard cell culture alters metabolism and function of differentiated cells. EMBO J43, 2127-2165. 10.1038/s44318-024-00084-7.
- van der Weyden, L., Del Castillo Velasco-Herrera, M., Cheema, S., Wong, K., Boccacino, J.M., Vermes, I., Offord, V., Droop, A., Jones, D.R.A., Anderson, E., Hardy, C., de Saint Aubain, N., Ferguson, P.M., Mogler, C., Rajan, N., Frew, D., Harms, P.W., Billings, S.D., Schatton, D., Segarra-Mondejar, M., Arends, M.J., Ferreira, I., Brenn, T., Frezza, C., and Adams, D.J. (2024). Exploration of the mutational landscape of cutaneous leiomyoma confirms FH as a driver gene and identifies targeting purine metabolism as a potential therapeutic strategy. Br J Dermatol10.1093/bjd/ljae432. 10.1093/bjd/ljae432.
To top
Ana J. García-Sáez
- Berndt, C., Alborzinia, H., Amen, V.S., Ayton, S., Barayeu, U., Bartelt, A., Bayir, H., Bebber, C.M., Birsoy, K., Bottcher, J.P., Brabletz, S., Brabletz, T., Brown, A.R., Brune, B., Bulli, G., Bruneau, A., Chen, Q., DeNicola, G.M., Dick, T.P., Distefano, A., Dixon, S.J., Engler, J.B., Esser-von Bieren, J., Fedorova, M., Friedmann Angeli, J.P., Friese, M.A., Fuhrmann, D.C., Garcia-Saez, A.J., Garbowicz, K., Gotz, M., Gu, W., Hammerich, L., Hassannia, B., Jiang, X., Jeridi, A., Kang, Y.P., Kagan, V.E., Konrad, D.B., Kotschi, S., Lei, P., Le Tertre, M., Lev, S., Liang, D., Linkermann, A., Lohr, C., Lorenz, S., Luedde, T., Methner, A., Michalke, B., Milton, A.V., Min, J., Mishima, E., Muller, S., Motohashi, H., Muckenthaler, M.U., Murakami, S., Olzmann, J.A., Pagnussat, G., Pan, Z., Papagiannakopoulos, T., Pedrera Puentes, L., Pratt, D.A., Proneth, B., Ramsauer, L., Rodriguez, R., Saito, Y., Schmidt, F., Schmitt, C., Schulze, A., Schwab, A., Schwantes, A., Soula, M., Spitzlberger, B., Stockwell, B.R., Thewes, L., Thorn-Seshold, O., Toyokuni, S., Tonnus, W., Trumpp, A., Vandenabeele, P., Vanden Berghe, T., Venkataramani, V., Vogel, F.C.E., von Karstedt, S., Wang, F., Westermann, F., Wientjens, C., Wilhelm, C., Wolk, M., Wu, K., Yang, X., Yu, F., Zou, Y., and Conrad, M. (2024). Ferroptosis in health and disease. Redox Biol75, 103211. 10.1016/j.redox.2024.103211.
- Dadsena, S., Cuevas Arenas, R., Vieira, G., Brodesser, S., Melo, M.N., and Garcia-Saez, A.J. (2024). Lipid unsaturation promotes BAX and BAK pore activity during apoptosis. Nat Commun15, 4700. 10.1038/s41467-024-49067-6.
- Dai, E., Chen, X., Linkermann, A., Jiang, X., Kang, R., Kagan, V.E., Bayir, H., Yang, W.S., Garcia-Saez, A.J., Ioannou, M.S., Janowitz, T., Ran, Q., Gu, W., Gan, B., Krysko, D.V., Zhu, X., Wang, J., Krautwald, S., Toyokuni, S., Xie, Y., Greten, F.R., Yi, Q., Schick, J., Liu, J., Gabrilovich, D.I., Liu, J., Zeh, H.J., Zhang, D.D., Yang, M., Iovanna, J., Kopf, M., Adolph, T.E., Chi, J.T., Li, C., Ichijo, H., Karin, M., Sankaran, V.G., Zou, W., Galluzzi, L., Bush, A.I., Li, B., Melino, G., Baehrecke, E.H., Lotze, M.T., Klionsky, D.J., Stockwell, B.R., Kroemer, G., and Tang, D. (2024). A guideline on the molecular ecosystem regulating ferroptosis. Nat Cell Biol26, 1447-1457. 10.1038/s41556-024-01360-8.
- Dellmann, T., Shalaby, R., and Garcia-Saez, A.J. (2024). Super-resolution microscopy methods to study membrane pores in situ. Methods Enzymol700, 161-187. 10.1016/bs.mie.2024.03.020.
- Freitas, F.P., Alborzinia, H., Dos Santos, A.F., Nepachalovich, P., Pedrera, L., Zilka, O., Inague, A., Klein, C., Aroua, N., Kaushal, K., Kast, B., Lorenz, S.M., Kunz, V., Nehring, H., Xavier da Silva, T.N., Chen, Z., Atici, S., Doll, S.G., Schaefer, E.L., Ekpo, I., Schmitz, W., Horling, A., Imming, P., Miyamoto, S., Wehman, A.M., Genaro-Mattos, T.C., Mirnics, K., Kumar, L., Klein-Seetharaman, J., Meierjohann, S., Weigand, I., Kroiss, M., Bornkamm, G.W., Gomes, F., Netto, L.E.S., Sathian, M.B., Konrad, D.B., Covey, D.F., Michalke, B., Bommert, K., Bargou, R.C., Garcia-Saez, A., Pratt, D.A., Fedorova, M., Trumpp, A., Conrad, M., and Friedmann Angeli, J.P. (2024). 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis. Nature626, 401-410. 10.1038/s41586-023-06878-9.
- Froehlich, T., Jenner, A., Cavarischia-Rega, C., Fagbadebo, F.O., Lurz, Y., Frecot, D.I., Kaiser, P.D., Nueske, S., Scholz, A.M., Schaffer, E., Garcia-Saez, A.J., Macek, B., and Rothbauer, U. (2024). Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1. Life Sci Alliance7. 10.26508/lsa.202402608.
- Garcia-Saez, A.J. (2024). Dying in self-defense: cell death signaling in animals and plants. Cell Death Differ31, 263-264. 10.1038/s41418-023-01206-0.
- Jenner, A., and Garcia-Saez, A.J. (2024). The regulation of the apoptotic pore-An immunological tightrope walk. Adv Immunol162, 59-108. 10.1016/bs.ai.2024.02.004.
- Lotfipour Nasudivar, S., Pedrera, L., and Garcia-Saez, A.J. (2024). Iron-Induced Lipid Oxidation Alters Membrane Mechanics Favoring Permeabilization. Langmuir40, 25061-25068. 10.1021/acs.langmuir.4c03294.
- Schmitt, L., Krings, K.S., Wolsing, A., Buque, X., Zimmermann, M., Flores-Romero, H., Lenz, T., Lechtenberg, I., Peter, C., Stork, B., Teusch, N., Proksch, P., Stuhler, K., Garcia-Saez, A.J., Reichert, A.S., Aspichueta, P., Bhatia, S., and Wesselborg, S. (2024). Targeting mitochondrial metabolism by the mitotoxin bromoxib in leukemia and lymphoma cells. Cell Commun Signal22, 541. 10.1186/s12964-024-01913-2.
- Schmitt, L., Lechtenberg, I., Driessen, D., Flores-Romero, H., Skowron, M.A., Sekeres, M., Hoppe, J., Krings, K.S., Llewellyn, T.R., Peter, C., Stork, B., Qin, N., Bhatia, S., Nettersheim, D., Fritz, G., Garcia-Saez, A.J., Muller, T.J.J., and Wesselborg, S. (2024). Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2. Cell Death Discov10, 125. 10.1038/s41420-024-01901-y.
Malte Gather
- Booth, J.H., Meek, A.T., Kronenberg, N.M., Pulver, S.R., and Gather, M.C. (2024). Optical mapping of ground reaction force dynamics in freely behaving Drosophila melanogaster larvae. Elife12. 10.7554/eLife.87746.
- Bryden, M.A., Millward, F., Lee, O.S., Cork, L., Gather, M.C., Steffen, A., and Zysman-Colman, E. (2024). Lessons learnt in photocatalysis - the influence of solvent polarity and the photostability of the photocatalyst. Chem Sci15, 3741-3757. 10.1039/d3sc06499a.
- Butscher, J.F., Hillebrandt, S., Mischok, A., Popczyk, A., Booth, J.H.H., and Gather, M.C. (2024). Wireless magnetoelectrically powered organic light-emitting diodes. Sci Adv10, eadm7613. 10.1126/sciadv.adm7613.
- Dalaka, E., Hill, J.S., Booth, J.H.H., Popczyk, A., Pulver, S.R., Gather, M.C., and Schubert, M. (2024). Deformable microlaser force sensing. Light Sci Appl13, 129. 10.1038/s41377-024-01471-9.
- Goll, F.D., Schelhorn, A., Litvinas, D., Tenopala-Carmona, F., Kazak, L., Jelezko, F., Lambert, C., Gather, M.C., Kuehne, A.J.C., and Ziener, U. (2024). Revealing the Origin of Fast Delayed Fluorescence in a Donor Functionalized Bisterpyridine. Chemistry30, e202303067. 10.1002/chem.202303067.
- Hillebrandt, S., Moon, C.K., Taal, A.J., Overhauser, H., Shepard, K.L., and Gather, M.C. (2024). High-Density Integration of Ultrabright OLEDs on a Miniaturized Needle-Shaped CMOS Backplane. Adv Mater36, e2300578. 10.1002/adma.202300578.
- Mischok, A., Siegmund, B., Le Roux, F., Hillebrandt, S., Vandewal, K., and Gather, M.C. (2024). Breaking the angular dispersion limit in thin film optics by ultra-strong light-matter coupling. Nat Commun15, 10529. 10.1038/s41467-024-54623-1.
- Sun, Y., Kronenberg, N.M., Sethi, S.K., Dash, S.N., Kovalik, M.E., Sempowski, B., Strickland, S., Raina, R., Sperati, C.J., Tian, X., Ishibe, S., Hall, G., and Gather, M.C. (2024). CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes. bioRxiv10.1101/2024.10.22.619513. 10.1101/2024.10.22.619513.
- Titze, V.M., Caixeiro, S., Dinh, V.S., Konig, M., Rubsam, M., Pathak, N., Schumacher, A.L., Germer, M., Kukat, C., Niessen, C.M., Schubert, M., and Gather, M.C. (2024). Hyperspectral confocal imaging for high-throughput readout and analysis of bio-integrated microlasers. Nat Protoc19, 928-959. 10.1038/s41596-023-00924-6.
- Witt, J., Mischok, A., Tenopala Carmona, F., Hillebrandt, S., Butscher, J.F., and Gather, M.C. (2024). High-Brightness Blue Polariton Organic Light-Emitting Diodes. ACS Photonics11, 1844-1850. 10.1021/acsphotonics.3c01610.
- Zhou, X., Gather, M.C., and Scarcelli, G. (2024). High-Sensitivity Detection of Changes in Local Refractive Index and Absorption by Analyzing WGM Microlaser Emission via a 2D Dispersion Spectrometer. ACS Photonics11, 267-275. 10.1021/acsphotonics.3c01448.
Martin Graef
- Gross, A.S., Ghillebert, R., Schuetter, M., Reinartz, E., Rowland, A., Bishop, B.C., Stumpe, M., Dengjel, J., and Graef, M. (2024). A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy. Nat Cell Biol26, 366-377. 10.1038/s41556-024-01348-4.
Michael Hallek
- Al-Sawaf, O., Robrecht, S., Zhang, C., Olivieri, S., Chang, Y.M., Fink, A.M., Tausch, E., Schneider, C., Ritgen, M., Kreuzer, K.A., Sivchev, L., Niemann, C.U., Schwarer, A., Loscertales, J., Weinkove, R., Strumberg, D., Kilfoyle, A., Manzoor, B.S., Jawaid, D., Emechebe, N., Devine, J., Boyer, M., Runkel, E.D., Eichhorst, B., Stilgenbauer, S., Jiang, Y., Hallek, M., and Fischer, K. (2024). Venetoclax-obinutuzumab for previously untreated chronic lymphocytic leukemia: 6-year results of the randomized phase 3 CLL14 study. Blood144, 1924-1935. 10.1182/blood.2024024631.
- Beielstein, A.C., Izquierdo, E., Blakemore, S., Nickel, N., Michalik, M., Chawan, S., Brinker, R., Bartel, H.H., Vorholt, D., Albert, L., Nolte, J.L., Linke, R., Costa Picossi, C.R., Saiz, J., Picard, F., Florin, A., Meinel, J., Buttner, R., Diefenhardt, P., Brahler, S., Villasenor, A., Winkels, H., Hallek, M., Kruger, M., Barbas, C., and Pallasch, C.P. (2024). Macrophages are activated toward phagocytic lymphoma cell clearance by pentose phosphate pathway inhibition. Cell Rep Med5, 101830. 10.1016/j.xcrm.2024.101830.
- Borchmann, P., Ferdinandus, J., Schneider, G., Moccia, A., Greil, R., Hertzberg, M., Schaub, V., Huttmann, A., Keil, F., Dierlamm, J., Hanel, M., Novak, U., Meissner, J., Zimmermann, A., Mathas, S., Zijlstra, J.M., Fossa, A., Viardot, A., Hertenstein, B., Martin, S., Giri, P., Scholl, S., Topp, M.S., Jung, W., Vucinic, V., Beck, H.J., Kerkhoff, A., Unger, B., Rank, A., Schroers, R., Zum Buschenfelde, C.M., de Wit, M., Trautmann-Grill, K., Kamper, P., Molin, D., Kreissl, S., Kaul, H., von Tresckow, B., Borchmann, S., Behringer, K., Fuchs, M., Rosenwald, A., Klapper, W., Eich, H.T., Baues, C., Zomas, A., Hallek, M., Dietlein, M., Kobe, C., Diehl, V., German Hodgkin Study, G., Swiss Group for Clinical Cancer, R., Arbeitsgemeinschaft Medikamentose, T., Nordic Lymphoma, G., Australasian, L., and Lymphoma, G. (2024). Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial. Lancet404, 341-352. 10.1016/S0140-6736(24)01315-1.
- Eichhorst, B., Ghia, P., Niemann, C.U., Kater, A.P., Gregor, M., Hallek, M., Jerkeman, M., Buske, C., and clinicalguidelines@esmo.org, E.G.C.E.a. (2024). ESMO Clinical Practice Guideline interim update on new targeted therapies in the first line and at relapse of chronic lymphocytic leukaemia. Ann Oncol35, 762-768. 10.1016/j.annonc.2024.06.016.
- Fischer, L., Jiang, L., Durig, J., Schmidt, C., Stilgenbauer, S., Bouabdallah, K., Solal-Celigny, P., Scholz, C.W., Feugier, P., de Wit, M., Trappe, R.U., Hallek, M., Graeven, U., Hanel, M., Hoffmann, M., Delwail, V., Macro, M., Greiner, J., Giagounidis, A.A.N., Dargel, B., Durot, E., Foussard, C., Silkenstedt, E., Weigert, O., Pott, C., Klapper, W., Hiddemann, W., Unterhalt, M., Hoster, E., Ribrag, V., and Dreyling, M. (2024). The addition of bortezomib to rituximab, high-dose cytarabine and dexamethasone in relapsed or refractory mantle cell lymphoma-a randomized, open-label phase III trial of the European mantle cell lymphoma network. Leukemia38, 1307-1314. 10.1038/s41375-024-02254-2.
- Furstenau, M., Kater, A.P., Robrecht, S., von Tresckow, J., Zhang, C., Gregor, M., Thornton, P., Staber, P.B., Tadmor, T., Lindstrom, V., Juliusson, G., Janssens, A., Levin, M.D., da Cunha-Bang, C., Schneider, C., Goldschmidt, N., Vandenberghe, E., Rossi, D., Benz, R., Nosslinger, T., Heintel, D., Poulsen, C.B., Christiansen, I., Frederiksen, H., Enggaard, L., Posthuma, E.F.M., Issa, D.E., Visser, H.P.J., Bellido, M., Kutsch, N., Durig, J., Stehle, A., Vohringer, M., Bottcher, S., Schulte, C., Simon, F., Fink, A.M., Fischer, K., Holmes, E.E., Kreuzer, K.A., Ritgen, M., Bruggemann, M., Tausch, E., Stilgenbauer, S., Hallek, M., Niemann, C.U., and Eichhorst, B. (2024). First-line venetoclax combinations versus chemoimmunotherapy in fit patients with chronic lymphocytic leukaemia (GAIA/CLL13): 4-year follow-up from a multicentre, open-label, randomised, phase 3 trial. Lancet Oncol25, 744-759. 10.1016/S1470-2045(24)00196-7.
- Jestrabek, H., Kohlhas, V., Hallek, M., and Nguyen, P.H. (2024). Impact of leukemia-associated macrophages on the progression and therapy response of chronic lymphocytic leukemia. Leuk Res143, 107531. 10.1016/j.leukres.2024.107531.
- Kutsch, N., Giza, A., Robrecht, S., Stumpf, J., Federhen, A., Stoltefuss, A., Vehling-Kaiser, U., Koenigsmann, M., Tausch, E., Schneider, C., Stilgenbauer, S., Illmer, T., Schlag, R., Dorfel, S., Gaska, T., Kiehl, M., Muller-Hagen, S., Moorahrend, E., Linde, H., Schlenska-Lange, A., von Tresckow, J., Fischer, K., Eichhorst, B., Hallek, M., and Fink, A.M. (2024). Fludarabine, cyclophosphamide, and rituximab as first-line treatment in patients with chronic lymphocytic leukemia: A long-term analysis of the German CLL Study Group (GCLLSG) registry. Eur J Haematol113, 235-241. 10.1111/ejh.14220.
- Kutsch, N., Gôdel, P., Voltin, C.A., Hallek, M., Scheid, C., Borchmann, P., and Holtick, U. (2024). Long-term remission in a patient with relapsed Richter's transformation treated with CD19-directed chimeric antigen-receptor T-cells after allogeneic stem cell transplantation. Eur J Haematol10.1111/ejh.14182. 10.1111/ejh.14182.
- Kutsch, N., Robrecht, S., Fink, A., Lange, E., Weide, R., Kiehl, M.G., Sokler, M., Schlag, R., Vehling-Kaiser, U., Kochling, G., Ploger, C., Gregor, M., Plesner, T., Clausen, M.R., Oschlies, I., Ritgen, M., Herling, M., Fischer, K., Dohner, H., Wendtner, C.M., Kreuzer, K.A., Stilgenbauer, S., Hallek, M., Bottcher, S., Klapper, W., and Eichhorst, B. (2024). The role of trephine bone marrow biopsies in the era of measurable residual disease-Results from the CLL10 trial of the German CLL Study Group (GCLLSG). Hemasphere8, e126. 10.1002/hem3.126.
- Langerbeins, P., Giza, A., Robrecht, S., Cramer, P., von Tresckow, J., Al-Sawaf, O., Fink, A.M., Furstenau, M., Kater, A.P., van der Spek, E., Niemann, C.U., da Cunha-Bang, C., Tausch, E., Schneider, C., Stilgenbauer, S., Fischer, K., Hallek, M., and Eichhorst, B. (2024). Infections in patients with chronic lymphocytic leukemia treated with time limited targeted drug combinations. Am J Hematol99, 1620-1623. 10.1002/ajh.27367.
- Lewis, R.I., Vom Stein, A.F., and Hallek, M. (2024). Targeting the tumor microenvironment for treating double-refractory chronic lymphocytic leukemia. Blood144, 601-614. 10.1182/blood.2023022861.
- Liedgens, P., Heger, J.M., Sieg, N., Garcia Borrega, J., Naendrup, J.H., Simon, F., Johannis, W., Hallek, M., Shimabukuro-Vornhagen, A., Kochanek, M., Boll, B., and Eichenauer, D.A. (2024). Marked hyperferritinemia in critically ill cancer patients. Eur J Haematol113, 493-500. 10.1111/ejh.14263.
- Meder, L., Orschel, C.I., Otto, C.J., Koker, M., Bragelmann, J., Ercanoglu, M.S., Dahling, S., Compes, A., Selenz, C., Nill, M., Dietlein, F., Florin, A., Eich, M.L., Borchmann, S., Odenthal, M., Blazquez, R., Hilberg, F., Klein, F., Hallek, M., Buttner, R., Reinhardt, H.C., and Ullrich, R.T. (2024). Blocking the angiopoietin-2-dependent integrin beta-1 signaling axis abrogates small cell lung cancer invasion and metastasis. Jci Insight9. 10.1172/jci.insight.166402.
- Mellinghoff, S.C., Robrecht, S., Sprute, R., Mayer, L., Weskamm, L.M., Dahlke, C., Gruell, H., Teipel, F., Schloesser, H.A., Siepmann, K., Thelen, M., Fink, A.M., Fischer, K., Klein, F., Addo, M.M., Kolovou, A., Cornely, O.A., Eichhorst, B., Hallek, M., and Langerbeins, P. (2024). Hybrid immunity to SARS-CoV-2 in patients with chronic lymphocytic leukemia. Eur J Haematol10.1111/ejh.14170. 10.1111/ejh.14170.
- Neumann, M.A., Naendrup, J.H., Garcia Borrega, J., Halmer, I., Altenrath, L., Sieg, N., Hallek, M., Eichenauer, D.A., and Heger, J.M. (2024). Characteristics, outcomes and health care utilization of patients with acute myeloid leukemia aged 70 years or older: A single-center retrospective analysis. Hematol Oncol42, e3300. 10.1002/hon.3300.
- Reimer, A., Ley, M., Schepers, C., Pralong, A., Schoerger, B., Voltz, R., Hallek, M., Herling, M., Holtick, U., and Simon, S.T. (2024). The life threat in hematopoietic allogeneic stem cell transplantation - an interview and focus group study on health care professionals' perspectives. Ann Hematol103, 4251-4259. 10.1007/s00277-024-05967-7.
- Streckmann, F., Elter, T., Lehmann, H.C., Baurecht, H., Nazarenus, T., Oschwald, V., Koliamitra, C., Otten, S., Draube, A., Heinen, P., Steinmetz, T., Hallek, M., Leitzmann, M., Bloch, W., and Balke, M. (2024). Preventive Effect of Neuromuscular Training on Chemotherapy-Induced Neuropathy: A Randomized Clinical Trial. JAMA Intern Med184, 1046-1053. 10.1001/jamainternmed.2024.2354.
- von Jan, J., Timonen, S., Braun, T., Jiang, Q., Ianevski, A., Peng, Y., McConnell, K., Sindaco, P., Muller, T.A., Putzer, S., Klepzig, H., Jungherz, D., Dechow, A., Wahnschaffe, L., Giri, A.K., Kankainen, M., Kuusanmaki, H., Neubauer, H.A., Moriggl, R., Mazzeo, P., Schmidt, N., Koch, R., Hallek, M., Chebel, A., Armisen, D., Genestier, L., Bachy, E., Mishra, A., Schrader, A., Aittokallio, T., Mustjoki, S., and Herling, M. (2024). Optimizing drug combinations for T-PLL: restoring DNA damage and P53-mediated apoptotic responses. Blood144, 1595-1610. 10.1182/blood.2023022884.
- Wilharm, C., Pralong, A., Weiss, M., Blutgen, S., Hallek, M., Voltz, R., Simon, S.T., and Tuchscherer, A. (2024). "The Most Important Thing is That You Are Not Left Alone"-A Qualitative Study of Challenges and Needs of Adolescents and Young Adults with Cancer. J Adolesc Young Adult Oncol13, 859-866. 10.1089/jayao.2023.0158.
- Simon, F., Ligtvoet, R., Robrecht, S., Cramer, P., Kutsch, N., Furstenau, M., Goede, V., von Tresckow, J., Langerbeins, P., Fink, A.M., Huber, H., Tausch, E., Schneider, C., Wendtner, C.M., Ritgen, M., Dreyling, M., Muller, L., Jacobasch, L., Heinz, W.J., Vehling-Kaiser, U., Sivcheva, L., Bottcher, S., Dreger, P., Illmer, T., Gregor, M., Staber, P.B., Stilgenbauer, S., Niemann, C.U., Kater, A.P., Fischer, K., Eichhorst, B., Hallek, M., and Al-Sawaf, O. (2025). End Point Surrogacy in First-Line Chronic Lymphocytic Leukemia. J Clin Oncol43, 381-391. 10.1200/JCO.24.01192.
To top
Robert Hänsel-Hertsch
- Sauer, P.V., Pavlenko, E., Cookis, T., Zirden, L.C., Renn, J., Singhal, A., Hunold, P., Hoehne-Wiechmann, M.N., van Ray, O., Kaschani, F., Kaiser, M., Hansel-Hertsch, R., Sanbonmatsu, K.Y., Nogales, E., and Poepsel, S. (2024). Activation of automethylated PRC2 by dimerization on chromatin. Mol Cell84, 3885-3898 e3888. 10.1016/j.molcel.2024.08.025.
- Frobel, J., and Hansel-Hertsch, R. (2025). The age-related decline of helicase function-how G-quadruplex structures promote genome instability. FEBS Lett599, 267-274. 10.1002/1873-3468.14939.
To top
Jan Hoeijmakers
- Erkelenz, S., Grzonka, M., Papadakis, A., Schaal, H., Hoeijmakers, J.H.J., and Gyenis, A. (2024). Rbm3 deficiency leads to transcriptome-wide splicing alterations. Rna Biol21, 1-13. 10.1080/15476286.2024.2413820.
- He, Y., Yang, W., Huang, L., Mever, M.A., Ramautar, R., Harms, A., Rijksen, Y., Brandt, R.M.C., Barnhoorn, S., Smit, K., Jaarsma, D., Lindenburg, P., Hoeijmakers, J.H.J., Vermeij, W.P., and Hankemeier, T. (2024). Metabolomic analysis of dietary-restriction-induced attenuation of sarcopenia in prematurely aging DNA repair-deficient mice. J Cachexia Sarcopenia Muscle15, 868-882. 10.1002/jcsm.13433.
- Jin, C., Wang, X., Yang, J., Kim, S., Hudgins, A.D., Gamliel, A., Pei, M., Contreras, D., Devos, M., Guo, Q., Vijg, J., Conti, M., Hoeijmakers, J., Campisi, J., Lobo, R., Williams, Z., Rosenfeld, M.G., and Suh, Y. (2024). Molecular and genetic insights into human ovarian aging from single-nuclei multi-omics analyses. Nat Aging10.1038/s43587-024-00762-5. 10.1038/s43587-024-00762-5.
- Llerena Schiffmacher, D.A., Lee, S.H., Kliza, K.W., Theil, A.F., Akita, M., Helfricht, A., Bezstarosti, K., Gonzalo-Hansen, C., van Attikum, H., Verlaan-de Vries, M., Vertegaal, A.C.O., Hoeijmakers, J.H.J., Marteijn, J.A., Lans, H., Demmers, J.A.A., Vermeulen, M., Sixma, T.K., Ogi, T., Vermeulen, W., and Pines, A. (2024). The small CRL4(CSA) ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics. Nat Commun15, 6374. 10.1038/s41467-024-50584-7.
- Oudmaijer, C.A.J., Komninos, D.S.J., Hoeijmakers, J.H.J., JNM, I.J., and Vermeij, W.P. (2024). Clinical implications of nutritional interventions reducing calories, a systematic scoping review. Clin Nutr Espen63, 427-439. 10.1016/j.clnesp.2024.06.046.
- Soheili-Nezhad, S., Ibanez-Sole, O., Izeta, A., Hoeijmakers, J.H.J., and Stoeger, T. (2024). Time is ticking faster for long genes in aging. Trends Genet40, 299-312. 10.1016/j.tig.2024.01.009.
- van Thiel, B.S., de Boer, M., Ridwan, Y., de Kleijnen, M.G.J., van Vliet, N., van der Linden, J., de Beer, I., van Heijningen, P.M., Vermeij, W.P., Hoeijmakers, J.H.J., Danser, A.H.J., Kanaar, R., Duncker, D.J., van der Pluijm, I., and Essers, J. (2024). Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice. Mol Imaging Biol26, 628-637. 10.1007/s11307-024-01902-4.
- Zhang, L., Lee, M., Hao, X., Ehlert, J., Chi, Z., Jin, B., Maslov, A.Y., Barabasi, A.L., Hoeijmakers, J.H.J., Edelmann, W., Vijg, J., and Dong, X. (2024). Negative Selection Allows DNA Mismatch Repair-Deficient Mouse Fibroblasts In Vitro to Tolerate High Levels of Somatic Mutations. bioRxiv10.1101/2024.05.04.592535. 10.1101/2024.05.04.592535.
Thorsten Hoppe
- Charmpilas, N., Sotiriou, A., Axarlis, K., Tavernarakis, N., and Hoppe, T. (2024). Reproductive regulation of the mitochondrial stress response in Caenorhabditis elegans. Cell Rep43, 114336. 10.1016/j.celrep.2024.114336.
- Das, A., Thapa, P., Santiago, U., Shanmugam, N., Banasiak, K., Dazbrowska, K., Nolte, H., Szulc, N.A., Gathungu, R.M., Cysewski, D., Krueger, M., Dadlez, M., Nowotny, M., Camacho, C.J., Hoppe, T., and Pokrzywa, W. (2024). Author Correction: A heterotypic assembly mechanism regulates CHIP E3 ligase activity. EMBO J43, 1110-1111. 10.1038/s44318-024-00042-3.
- Kutzner, C.E., Bauer, K.C., Lackmann, J.W., Acton, R.J., Sarkar, A., Pokrzywa, W., and Hoppe, T. (2024). Optogenetic induction of mechanical muscle stress identifies myosin regulatory ubiquitin ligase NHL-1 in C. elegans. Nat Commun15, 6879. 10.1038/s41467-024-51069-3.
- Muller, L., and Hoppe, T. (2024). UPS-dependent strategies of protein quality control degradation. Trends Biochem Sci49, 859-874. 10.1016/j.tibs.2024.06.006.
- Muller, L., Salman, S., and Hoppe, T. (2024). Chemical cross-linking to study protein self-assembly in cellulo. STAR Protoc5, 103032. 10.1016/j.xpro.2024.103032.
- Ottens, F., Efstathiou, S., and Hoppe, T. (2024). Cutting through the stress: RNA decay pathways at the endoplasmic reticulum. Trends Cell Biol34, 1056-1068. 10.1016/j.tcb.2023.11.003.
- Thapa, P., Chikale, R., Szulc, N.A., Pandrea, M.T., Sztyler, A., Jaggi, K., Niklewicz, M., Serwa, R.A., Hoppe, T., and Pokrzywa, W. (2024). HSP70 inhibits CHIP E3 ligase activity to maintain germline function in Caenorhabditis elegans. J Biol Chem300, 1-8. Available at: <Go to ISI>://WOS:001350897600001.
- Thapa, P., Chikale, R.V., Szulc, N.A., Pandrea, M.T., Sztyler, A., Jaggi, K., Niklewicz, M., Serwa, R.A., Hoppe, T., and Pokrzywa, W. (2024). HSP70 inhibits CHIP E3 ligase activity to maintain germline function in Caenorhabditis elegans. J Biol Chem300, 107864. 10.1016/j.jbc.2024.107864.
Pitter Huesgen
- Mooney, B.C., Doorly, C.M., Mantz, M., Garcia, P., Huesgen, P.F., and Graciet, E. (2024). Hypoxia represses pattern-triggered immune responses in Arabidopsis. Plant Physiol196, 2064-2077. 10.1093/plphys/kiae432.
- van Midden, K.P., Mantz, M., Fonovic, M., Gazvoda, M., Svete, J., Huesgen, P.F., van der Hoorn, R.A.L., and Klemencic, M. (2024). Mechanistic insights into CrCEP1: A dual-function cysteine protease with endo- and transpeptidase activity. Int J Biol Macromol271, 132505. 10.1016/j.ijbiomac.2024.132505.
- Zhang, W., Planas-Marques, M., Mazier, M., Simkovicova, M., Rocafort, M., Mantz, M., Huesgen, P.F., Takken, F.L.W., Stintzi, A., Schaller, A., Coll, N.S., and Valls, M. (2024). The tomato P69 subtilase family is involved in resistance to bacterial wilt. Plant J118, 388-404. 10.1111/tpj.16613.
- Junglas, B., Hudina, E., Schonnenbeck, P., Ritter, I., Heddier, A., Santiago-Schubel, B., Huesgen, P.F., Schneider, D., and Sachse, C. (2025). Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies. Nat Struct Mol Biol32, 23-34. 10.1038/s41594-024-01359-7.
Ina Huppertz
- Huppertz, I. (2024). Free ribosomal proteins as culprits for nucleolar stress. Mol Cell84, 1400-1402. 10.1016/j.molcel.2024.03.026.
Christina Ising
- Heneka, M.T., van der Flier, W.M., Jessen, F., Hoozemanns, J., Thal, D.R., Boche, D., Brosseron, F., Teunissen, C., Zetterberg, H., Jacobs, A.H., Edison, P., Ramirez, A., Cruchaga, C., Lambert, J.C., Laza, A.R., Sanchez-Mut, J.V., Fischer, A., Castro-Gomez, S., Stein, T.D., Kleineidam, L., Wagner, M., Neher, J.J., Cunningham, C., Singhrao, S.K., Prinz, M., Glass, C.K., Schlachetzki, J.C.M., Butovsky, O., Kleemann, K., De Jaeger, P.L., Scheiblich, H., Brown, G.C., Landreth, G., Moutinho, M., Grutzendler, J., Gomez-Nicola, D., McManus, R.M., Andreasson, K., Ising, C., Karabag, D., Baker, D.J., Liddelow, S.A., Verkhratsky, A., Tansey, M., Monsonego, A., Aigner, L., Dorothee, G., Nave, K.A., Simons, M., Constantin, G., Rosenzweig, N., Pascual, A., Petzold, G.C., Kipnis, J., Venegas, C., Colonna, M., Walter, J., Tenner, A.J., O'Banion, M.K., Steinert, J.R., Feinstein, D.L., Sastre, M., Bhaskar, K., Hong, S., Schafer, D.P., Golde, T., Ransohoff, R.M., Morgan, D., Breitner, J., Mancuso, R., and Riechers, S.P. (2024). Neuroinflammation in Alzheimer disease. Nat Rev Immunol10.1038/s41577-024-01104-7. 10.1038/s41577-024-01104-7.
- Karabag, D., Heneka, M.T., and Ising, C. (2024). The putative contribution of cellular senescence to driving tauopathies. Trends Immunol45, 837-848. 10.1016/j.it.2024.08.006.
To top
Ron Jachimowicz
- Dreyling, M., Doorduijn, J., Gine, E., Jerkeman, M., Walewski, J., Hutchings, M., Mey, U., Riise, J., Trneny, M., Vergote, V., Shpilberg, O., Gomes da Silva, M., Leppa, S., Jiang, L., Stilgenbauer, S., Kerkhoff, A., Jachimowicz, R.D., Celli, M., Hess, G., Arcaini, L., Visco, C., van Meerten, T., Wirths, S., Zinzani, P.L., Novak, U., Herhaus, P., Benedetti, F., Sonnevi, K., Hanoun, C., Hanel, M., Dierlamm, J., Pott, C., Klapper, W., Gozel, D., Schmidt, C., Unterhalt, M., Ladetto, M., and Hoster, E. (2024). Ibrutinib combined with immunochemotherapy with or without autologous stem-cell transplantation versus immunochemotherapy and autologous stem-cell transplantation in previously untreated patients with mantle cell lymphoma (TRIANGLE): a three-arm, randomised, open-label, phase 3 superiority trial of the European Mantle Cell Lymphoma Network. Lancet403, 2293-2306. 10.1016/S0140-6736(24)00184-3.
- Flumann, R., Hansen, J., Meinel, J., Pfeiffer, P., Goldfarb Wittkopf, H., Lutz, A., Wirtz, J., Mollmann, M., Zhou, T., Tabatabai, A., Lohmann, T., Jauch, M., Beleggia, F., Pelzer, B., Ullrich, F., Hofmann, S., Arora, A., Persigehl, T., Buttner, R., von Tresckow, B., Klein, S., Jachimowicz, R.D., Reinhardt, H.C., and Knittel, G. (2024). An inducible Cd79b mutation confers ibrutinib sensitivity in mouse models of Myd88-driven diffuse large B-cell lymphoma. Blood Adv8, 1063-1074. 10.1182/bloodadvances.2023011213.
- Kaade, E., Mausbach, S., Erps, N., Sylvester, M., Shakeri, F., Jachimowicz, R.D., Gieselmann, V., and Thelen, M. (2024). Starvation-induced metabolic rewiring affects mTORC1 composition in vivo. Sci Rep14, 28296. 10.1038/s41598-024-78873-7.
- Wagener, R., Brandes, D., Jung, M., Huetzen, M.A., Bergmann, A.K., Panier, S., Picard, D., Fischer, U., Jachimowicz, R.D., Borkhardt, A., and Brozou, T. (2024). Optical genome mapping identifies structural variants in potentially new cancer predisposition candidate genes in pediatric cancer patients. Int J Cancer154, 607-614. 10.1002/ijc.34721.
Frank Jessen
- Baumeister, H., Vogel, J.W., Insel, P.S., Kleineidam, L., Wolfsgruber, S., Stark, M., Gellersen, H.M., Yakupov, R., Schmid, M.C., Lusebrink, F., Brosseron, F., Ziegler, G., Freiesleben, S.D., Preis, L., Schneider, L.S., Spruth, E.J., Altenstein, S., Lohse, A., Fliessbach, K., Vogt, I.R., Bartels, C., Schott, B.H., Rostamzadeh, A., Glanz, W., Incesoy, E.I., Butryn, M., Janowitz, D., Rauchmann, B.S., Kilimann, I., Goerss, D., Munk, M.H., Hetzer, S., Dechent, P., Ewers, M., Scheffler, K., Wuestefeld, A., Strandberg, O., van Westen, D., Mattsson-Carlgren, N., Janelidze, S., Stomrud, E., Palmqvist, S., Spottke, A., Laske, C., Teipel, S., Perneczky, R., Buerger, K., Schneider, A., Priller, J., Peters, O., Ramirez, A., Wiltfang, J., Heneka, M.T., Wagner, M., Duzel, E., Jessen, F., Hansson, O., and Berron, D. (2024). A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings. Brain147, 2400-2413. 10.1093/brain/awae118.
- Bernal, J., Menze, I., Yakupov, R., Peters, O., Hellmann-Regen, J., Freiesleben, S.D., Priller, J., Spruth, E.J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Schott, B.H., Jessen, F., Rostamzadeh, A., Glanz, W., Incesoy, E.I., Buerger, K., Janowitz, D., Ewers, M., Perneczky, R., Rauchmann, B.S., Teipel, S., Kilimann, I., Laske, C., Sodenkamp, S., Spottke, A., Esser, A., Lusebrink, F., Dechent, P., Hetzer, S., Scheffler, K., Schreiber, S., Duzel, E., and Ziegler, G. (2024). Longitudinal evidence for a mutually reinforcing relationship between white matter hyperintensities and cortical thickness in cognitively unimpaired older adults. Alzheimers Res Ther16, 240. 10.1186/s13195-024-01606-5.
- Bischof, G.N., Jaeger, E., Giehl, K., Jessen, F., Onur, O.A., O'Bryant, S., Kara, E., Weiss, P.H., and Drzezga, A. (2024). Cortical Tau Aggregation Patterns Associated With Apraxia in Patients With Alzheimer Disease. Neurology103, e210062. 10.1212/WNL.0000000000210062.
- Dafsari, F.S., Bewernick, B., Böhringer, S., Domschke, K., Elsaesser, M., Löbner, M., Luppa, M., Schmitt, S., Wingenfeld, K., Wolf, E., Zehender, N., Hellmich, M., Müller, W., Wagner, M., Peters, O., Frölich, L., Riedel-Heller, S., Schramm, E., Hautzinger, M., and Jessen, F. (2024). Perceived Physical Health and Cognitive Behavioral Therapy vs Supportive Psychotherapy Outcomes in Adults With Late-Life Depression A Secondary Analysis of a Randomized Clinical Trial. Jama Network Open7. 10.1001/jamanetworkopen.2024.5841.
- Deike, K., Decker, A., Scheyhing, P., Harten, J., Zimmermann, N., Paech, D., Peters, O., Freiesleben, S.D., Schneider, L.S., Preis, L., Priller, J., Spruth, E., Altenstein, S., Lohse, A., Fliessbach, K., Kimmich, O., Wiltfang, J., Bartels, C., Hansen, N., Jessen, F., Rostamzadeh, A., Duzel, E., Glanz, W., Incesoy, E.I., Butryn, M., Buerger, K., Janowitz, D., Ewers, M., Perneczky, R., Rauchmann, B.S., Teipel, S., Kilimann, I., Goerss, D., Laske, C., Munk, M.H., Spottke, A., Roy, N., Wagner, M., Roeske, S., Heneka, M.T., Brosseron, F., Ramirez, A., Dobisch, L., Wolfsgruber, S., Kleineidam, L., Yakupov, R., Stark, M., Schmid, M.C., Berger, M., Hetzer, S., Dechent, P., Scheffler, K., Petzold, G.C., Schneider, A., Effland, A., and Radbruch, A. (2024). Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease. Invest Radiol59, 667-676. 10.1097/RLI.0000000000001077.
- Doering, E., Antonopoulos, G., Hoenig, M., van Eimeren, T., Daamen, M., Boecker, H., Jessen, F., Duzel, E., Eickhoff, S., Patil, K., Drzezga, A., Alzheimer's Disease Neuroimaging, I., and the, D.S.G. (2024). MRI or (18)F-FDG PET for Brain Age Gap Estimation: Links to Cognition, Pathology, and Alzheimer Disease Progression. J Nucl Med65, 147-155. 10.2967/jnumed.123.265931.
- Dubois, B., Villain, N., Schneider, L., Fox, N., Campbell, N., Galasko, D., Kivipelto, M., Jessen, F., Hanseeuw, B., Boada, M., Barkhof, F., Nordberg, A., Froelich, L., Waldemar, G., Frederiksen, K.S., Padovani, A., Planche, V., Rowe, C., Bejanin, A., Ibanez, A., Cappa, S., Caramelli, P., Nitrini, R., Allegri, R., Slachevsky, A., de Souza, L.C., Bozoki, A., Widera, E., Blennow, K., Ritchie, C., Agronin, M., Lopera, F., Delano-Wood, L., Bombois, S., Levy, R., Thambisetty, M., Georges, J., Jones, D.T., Lavretsky, H., Schott, J., Gatchel, J., Swantek, S., Newhouse, P., Feldman, H.H., and Frisoni, G.B. (2024). Alzheimer Disease as a Clinical-Biological Construct-An International Working Group Recommendation. JAMA Neurol81, 1304-1311. 10.1001/jamaneurol.2024.3770.
- Dunnwald, M., Krohn, F., Sciarra, A., Sarkar, M., Schneider, A., Fliessbach, K., Kimmich, O., Jessen, F., Rostamzadeh, A., Glanz, W., Incesoy, E.I., Teipel, S., Kilimann, I., Goerss, D., Spottke, A., Brustkern, J., Heneka, M.T., Brosseron, F., Lusebrink, F., Hammerer, D., Duzel, E., Tonnies, K., Oeltze-Jafra, S., and Betts, M.J. (2024). Fully Automated MRI-based Analysis of the Locus Coeruleus in Aging and Alzheimer's Disease Dementia using ELSI-Net. bioRxiv10.1101/2024.07.26.605356. 10.1101/2024.07.26.605356.
- Frisoni, G.B., Festari, C., Massa, F., Cotta Ramusino, M., Orini, S., Aarsland, D., Agosta, F., Babiloni, C., Borroni, B., Cappa, S.F., Frederiksen, K.S., Froelich, L., Garibotto, V., Haliassos, A., Jessen, F., Kamondi, A., Kessels, R.P., Morbelli, S.D., O'Brien, J.T., Otto, M., Perret-Liaudet, A., Pizzini, F.B., Vandenbulcke, M., Vanninen, R., Verhey, F., Vernooij, M.W., Yousry, T., Boada Rovira, M., Dubois, B., Georges, J., Hansson, O., Ritchie, C.W., Scheltens, P., van der Flier, W.M., and Nobili, F. (2024). European intersocietal recommendations for the biomarker-based diagnosis of neurocognitive disorders. Lancet Neurol23, 302-312. 10.1016/S1474-4422(23)00447-7.
- Hayek, D., Ziegler, G., Kleineidam, L., Brosseron, F., Nemali, A., Vockert, N., Ravichandran, K.A., Betts, M.J., Peters, O., Schneider, L.S., Wang, X., Priller, J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Bartels, C., Rostamzadeh, A., Glanz, W., Buerger, K., Janowitz, D., Perneczky, R., Rauchmann, B.S., Teipel, S., Kilimann, I., Laske, C., Mengel, D., Synofzik, M., Munk, M.H., Spottke, A., Roy, N., Roeske, S., Kuhn, E., Ramirez, A., Dobisch, L., Schmid, M., Berger, M., Wolfsgruber, S., Yakupov, R., Hetzer, S., Dechent, P., Ewers, M., Scheffler, K., Schott, B.H., Schreiber, S., Orellana, A., de Rojas, I., Marquie, M., Boada, M., Sotolongo, O., Gonzalez, P.G., Puerta, R., Duzel, E., Jessen, F., Wagner, M., Ruiz, A., Heneka, M.T., and Maass, A. (2024). Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition. Mol Psychiatry29, 992-1004. 10.1038/s41380-023-02387-3.
- Heneka, M.T., Morgan, D., and Jessen, F. (2024). Passive anti-amyloid beta immunotherapy in Alzheimer's disease-opportunities and challenges. Lancet404, 2198-2208. 10.1016/S0140-6736(24)01883-X.
- Heneka, M.T., van der Flier, W.M., Jessen, F., Hoozemanns, J., Thal, D.R., Boche, D., Brosseron, F., Teunissen, C., Zetterberg, H., Jacobs, A.H., Edison, P., Ramirez, A., Cruchaga, C., Lambert, J.C., Laza, A.R., Sanchez-Mut, J.V., Fischer, A., Castro-Gomez, S., Stein, T.D., Kleineidam, L., Wagner, M., Neher, J.J., Cunningham, C., Singhrao, S.K., Prinz, M., Glass, C.K., Schlachetzki, J.C.M., Butovsky, O., Kleemann, K., De Jaeger, P.L., Scheiblich, H., Brown, G.C., Landreth, G., Moutinho, M., Grutzendler, J., Gomez-Nicola, D., McManus, R.M., Andreasson, K., Ising, C., Karabag, D., Baker, D.J., Liddelow, S.A., Verkhratsky, A., Tansey, M., Monsonego, A., Aigner, L., Dorothee, G., Nave, K.A., Simons, M., Constantin, G., Rosenzweig, N., Pascual, A., Petzold, G.C., Kipnis, J., Venegas, C., Colonna, M., Walter, J., Tenner, A.J., O'Banion, M.K., Steinert, J.R., Feinstein, D.L., Sastre, M., Bhaskar, K., Hong, S., Schafer, D.P., Golde, T., Ransohoff, R.M., Morgan, D., Breitner, J., Mancuso, R., and Riechers, S.P. (2024). Neuroinflammation in Alzheimer disease. Nat Rev Immunol10.1038/s41577-024-01104-7. 10.1038/s41577-024-01104-7.
- Herrmann, C., Werner, B., Wurster, F., Karbach, U., Leikert, C., Nordmeyer, L., Meixner, A., Sannemann, L., Albus, C., Jessen, F., Kuntz, L., Schulz-Nieswandt, F., Pfaff, H., Cologne, R., and Development Network Study, G. (2024). A tailored intervention for the detection of patients with coronary heart disease and mental or cognitive comorbidities in the German primary care setting: qualitative evaluation of implementation success. BMC Health Serv Res24, 1454. 10.1186/s12913-024-11841-z.
- Honig, M., Altomare, D., Caprioglio, C., Collij, L., Barkhof, F., Van Berckel, B., Scheltens, P., Farrar, G., Battle, M.R., Theis, H., Giehl, K., Bischof, G.N., Garibotto, V., Molinuevo, J.L.L., Grau-Rivera, O., Delrieu, J., Payoux, P., Demonet, J.F., Nordberg, A.K., Savitcheva, I., Walker, Z., Edison, P., Stephens, A.W., Gismondi, R., Jessen, F., Buckley, C.J., Gispert, J.D., Frisoni, G.B., Drzezga, A., and Consortium, A. (2024). Association Between Years of Education and Amyloid Burden in Patients With Subjective Cognitive Decline, MCI, and Alzheimer Disease. Neurology102, e208053. 10.1212/WNL.0000000000208053.
- Jessen, F., Frolich, L., Hort, J., Winblad, B., and Fortea, J. (2024). Amyloid-lowering treatment in Alzheimer's disease. Lancet404, 2161-2162. 10.1016/S0140-6736(24)02510-8.
- Jessen, F., Kramberger, M.G., Angioni, D., Aarsland, D., Balasa, M., Bennys, K., Boada, M., Boban, M., Chincarini, A., Exalto, L., Felbecker, A., Fliessbach, K., Frisoni, G.B., Garza-Martinez, A.J., Grimmer, T., Hanseeuw, B., Hort, J., Ivanoiu, A., Kloppel, S., Krajcovicova, L., McGuinness, B., Mecocci, P., de Mendonca, A., Nous, A., Ousset, P.J., Paquet, C., Perneczky, R., Peters, O., Tabuas-Pereira, M., Piazza, F., Plantone, D., Riverol, M., Ruiz, A., Sacco, G., Santana, I., Scarmeas, N., Solje, E., Stefanova, E., Sutovsky, S., van der Flier, W., Welsh, T., Wimo, A., Winblad, B., Frolich, L., and Engelborghs, S. (2024). Progress in the Treatment of Alzheimer's Disease Is Needed - Position Statement of European Alzheimer's Disease Consortium (EADC) Investigators. J Prev Alzheimers Dis11, 1212-1218. 10.14283/jpad.2024.153.
- Konig, A., Kohler, S., Troger, J., Duzel, E., Glanz, W., Butryn, M., Mallick, E., Priller, J., Altenstein, S., Spottke, A., Kimmich, O., Falkenburger, B., Osterrath, A., Wiltfang, J., Bartels, C., Kilimann, I., Laske, C., Munk, M.H., Roeske, S., Frommann, I., Hoffmann, D.C., Jessen, F., Wagner, M., Linz, N., and Teipel, S. (2024). Automated remote speech-based testing of individuals with cognitive decline: Bayesian agreement of transcription accuracy. Alzheimers Dement (Amst)16, e70011. 10.1002/dad2.70011.
- Le Borgne, J., Gomez, L., Heikkinen, S., Amin, N., Ahmad, S., Choi, S.H., Bis, J., Grenier-Boley, B., Rodriguez, O.G., Kleineidam, L., Young, J., Tripathi, K.P., Wang, L., Varma, A., Campos-Martin, R., van der Lee, S., Damotte, V., de Rojas, I., Palmal, S., Eadb, G.R.A.C.E.D.E.G.D.F.A.C., Lipton, R., Reiman, E., McKee, A., De Jager, P., Bush, W., Small, S., Levey, A., Saykin, A., Foroud, T., Albert, M., Hyman, B., Petersen, R., Younkin, S., Sano, M., Wisniewski, T., Vassar, R., Schneider, J., Henderson, V., Roberson, E., DeCarli, C., LaFerla, F., Brewer, J., Swerdlow, R., Van Eldik, L., Hamilton-Nelson, K., Paulson, H., Naj, A., Lopez, O., Chui, H., Crane, P., Grabowski, T., Kukull, W., Asthana, S., Craft, S., Strittmatter, S., Cruchaga, C., Leverenz, J., Goate, A., Kamboh, M.I., George-Hyslop, P.S., Valladares, O., Kuzma, A., Cantwell, L., Riemenschneider, M., Morris, J., Slifer, S., Dalmasso, C., Castillo, A., Kucukali, F., Peters, O., Schneider, A., Dichgans, M., Rujescu, D., Scherbaum, N., Deckert, J., Riedel-Heller, S., Hausner, L., Molina-Porcel, L., Duzel, E., Grimmer, T., Wiltfang, J., Heilmann-Heimbach, S., Moebus, S., Tegos, T., Scarmeas, N., Dols-Icardo, O., Moreno, F., Perez-Tur, J., Bullido, M.J., Pastor, P., Sanchez-Valle, R., Alvarez, V., Boada, M., Garcia-Gonzalez, P., Puerta, R., Mir, P., Real, L.M., Pinol-Ripoll, G., Garcia-Alberca, J.M., Royo, J.L., Rodriguez-Rodriguez, E., Soininen, H., de Mendonca, A., Mehrabian, S., Traykov, L., Hort, J., Vyhnalek, M., Thomassen, J.Q., Pijnenburg, Y.A.L., Holstege, H., van Swieten, J., Ramakers, I., Verhey, F., Scheltens, P., Graff, C., Papenberg, G., Giedraitis, V., Boland, A., Deleuze, J.F., Nicolas, G., Dufouil, C., Pasquier, F., Hanon, O., Debette, S., Grunblatt, E., Popp, J., Ghidoni, R., Galimberti, D., Arosio, B., Mecocci, P., Solfrizzi, V., Parnetti, L., Squassina, A., Tremolizzo, L., Borroni, B., Nacmias, B., Spallazzi, M., Seripa, D., Rainero, I., Daniele, A., Bossu, P., Masullo, C., Rossi, G., Jessen, F., Fernandez, V., Kehoe, P.G., Frikke-Schmidt, R., Tsolaki, M., Sanchez-Juan, P., Sleegers, K., Ingelsson, M., Haines, J., Farrer, L., Mayeux, R., Wang, L.S., Sims, R., DeStefano, A., Schellenberg, G.D., Seshadri, S., Amouyel, P., Williams, J., van der Flier, W., Ramirez, A., Pericak-Vance, M., Andreassen, O.A., Van Duijn, C., Hiltunen, M., Ruiz, A., Dupuis, J., Martin, E., Lambert, J.C., Kunkle, B., and Bellenguez, C. (2024). X-chromosome-wide association study for Alzheimer's disease. Mol Psychiatry10.1038/s41380-024-02838-5. 10.1038/s41380-024-02838-5.
- Li, X.Y., Yuan, L.X., Ding, C.C., Guo, T.F., Du, W.Y., Jiang, J.H., Jessen, F., Zang, Y.F., and Han, Y. (2024). Convergent Multimodal Imaging Abnormalities in the Dorsal Precuneus in Subjective Cognitive Decline. J Alzheimers Dis101, 589-601. 10.3233/JAD-231360.
- Menze, I., Bernal, J., Kaya, P., Aki, C., Pfister, M., Geisendorfer, J., Yakupov, R., Coello, R.D., Valdes-Hernandez, M.D.C., Heneka, M.T., Brosseron, F., Schmid, M.C., Glanz, W., Incesoy, E.I., Butryn, M., Rostamzadeh, A., Meiberth, D., Peters, O., Preis, L., Lammerding, D., Gref, D., Priller, J., Spruth, E.J., Altenstein, S., Lohse, A., Hetzer, S., Schneider, A., Fliessbach, K., Kimmich, O., Vogt, I.R., Wiltfang, J., Bartels, C., Schott, B.H., Hansen, N., Dechent, P., Buerger, K., Janowitz, D., Perneczky, R., Rauchmann, B.S., Teipel, S., Kilimann, I., Goerss, D., Laske, C., Munk, M.H., Sanzenbacher, C., Hinderer, P., Scheffler, K., Spottke, A., Roy-Kluth, N., Lusebrink, F., Neumann, K., Wardlaw, J., Jessen, F., Schreiber, S., Duzel, E., and Ziegler, G. (2024). Perivascular space enlargement accelerates in ageing and Alzheimer's disease pathology: evidence from a three-year longitudinal multicentre study. Alzheimers Res Ther16, 242. 10.1186/s13195-024-01603-8.
- Nordmeyer, L., Leikert, C., Sannemann, L., Keller, K., Leminski, C., Meixner, A., Peltzer, S., Werner, B., Kuntz, L., Pfaff, H., Schulz-Nieswandt, F., Jessen, F., Albus, C., Cologne, R., and Development Network Study, G. (2024). Quality of health care for patients with coronary heart disease and comorbid mental disorders: a prospective cohort study. BMC Psychol12, 288. 10.1186/s40359-024-01693-x.
- Pestana, P.C., Cardoso, S., Guerreiro, M., Maroco, J., Jessen, F., do Couto, F.S., and de Mendonca, A. (2024). Frequency, sociodemographic, and neuropsychological features of patients with subjective cognitive decline diagnosed using different neuropsychological criteria. Alzheimers Res Ther16, 261. 10.1186/s13195-024-01634-1.
- Preis, L., Villringer, K., Brosseron, F., Duzel, E., Jessen, F., Petzold, G.C., Ramirez, A., Spottke, A., Fiebach, J.B., and Peters, O. (2024). Assessing blood-brain barrier dysfunction and its association with Alzheimer's pathology, cognitive impairment and neuroinflammation. Alzheimers Res Ther16, 172. 10.1186/s13195-024-01529-1.
- Rostamzadeh, A., Kalthegener, F., Schwegler, C., Romotzky, V., Gil-Navarro, S., Rosende-Roca, M., Ortega, G., Canabate, P., Moreno, M., Maier, F., Zeyen, P., Schild, A.K., Meiberth, D., Sannemann, L., Bohr, L., Schmitz-Luhn, B., Boada, M., Woopen, C., and Jessen, F. (2024). Psychological outcomes of dementia risk estimation in MCI patients: Results from the PreDADQoL project. Alzheimers Dement20, 7635-7656. 10.1002/alz.14226.
- Ruiz-Rizzo, A.L., Finke, K., Damoiseaux, J.S., Bartels, C., Buerger, K., Cosma, N.C., Dechent, P., Dobisch, L., Ewers, M., Fliessbach, K., Frommann, I., Glanz, W., Goerss, D., Hetzer, S., Incesoy, E.I., Janowitz, D., Kilimann, I., Laske, C., van Lent, D.M., Munk, M.H.J., Peters, O., Priller, J., Ramirez, A., Rostamzadeh, A., Roy, N., Scheffler, K., Schneider, A., Spottke, A., Spruth, E.J., Teipel, S., Wagner, M., Wiltfang, J., Yakupov, R., Jessen, F., Duezel, E., Perneczky, R., and Rauchmann, B.S. (2024). Fornix fractional anisotropy mediates the association between Mediterranean diet adherence and memory four years later in older adults without dementia. Neurobiol Aging136, 99-110. 10.1016/j.neurobiolaging.2024.01.012.
- Shao, K., Hu, X., Kleineidam, L., Stark, M., Altenstein, S., Amthauer, H., Boecker, H., Buchert, R., Buerger, K., Butryn, M., Cai, Y., Cai, Y., Cosma, N.C., Chen, G., Chen, Z., Daamen, M., Drzezga, A., Duzel, E., Essler, M., Ewers, M., Fliessbach, K., Gaertner, F.C., Glanz, W., Guo, T., Hansen, N., He, B., Janowitz, D., Kilimann, I., Krause, B.J., Lan, G., Lange, C., Laske, C., Li, Y., Li, R., Liu, L., Lu, J., Meng, F., Munk, M.H., Peters, O., Perneczky, R., Priller, J., Ramirez, A., Rauchmann, B.S., Reimold, M., Rominger, A., Rostamzadeh, A., Roy-Kluth, N., Schneider, A., Spottke, A., Spruth, E.J., Sun, P., Teipel, S., Wang, X., Wei, M., Wei, Y., Wiltfang, J., Yan, S., Yang, J., Yu, X., Zhang, M., Zhang, L., Delcode study group, S.s.g., Wagner, M., Jessen, F., Han, Y., and Kuhn, E. (2024). Amyloid and SCD jointly predict cognitive decline across Chinese and German cohorts. Alzheimers Dement20, 5926-5939. 10.1002/alz.14119.
- Soch, J., Richter, A., Kizilirmak, J.M., Schutze, H., Ziegler, G., Altenstein, S., Brosseron, F., Dechent, P., Fliessbach, K., Freiesleben, S.D., Glanz, W., Gref, D., Heneka, M.T., Hetzer, S., Incesoy, E.I., Kilimann, I., Kimmich, O., Kleineidam, L., Kuhn, E., Laske, C., Lohse, A., Lusebrink, F., Munk, M.H., Peters, O., Preis, L., Priller, J., Ramirez, A., Roeske, S., Rostamzadeh, A., Roy-Kluth, N., Scheffler, K., Schmid, M., Schneider, A., Spottke, A., Spruth, E.J., Teipel, S., Wiltfang, J., Jessen, F., Wagner, M., Duzel, E., and Schott, B.H. (2024). Single-value brain activity scores reflect both severity and risk across the Alzheimer's continuum. Brain147, 3789-3803. 10.1093/brain/awae149.
- Teipel, S.J., Dyrba, M., Kleineidam, L., Brosseron, F., Levin, F., Bruno, D., Buerger, K., Cosma, N., Schneider, L.S., Düzel, E., Glanz, W., Fliessbach, K., Janowitz, D., Kilimann, I., Laske, C., Munk, M.H., Maier, F., Peters, O., Pomara, N., Perneczky, R., Rauchmann, B.S., Priller, J., Ramirez, A., Roy, N., Schneider, A., Spottke, A., Spruth, E.J., Roeske, S., Wagner, M., Wiltfang, J., Wolfsgruber, S., Bartels, C., Jessen, F., Heneka, M.T., and Alzheimert, D.S.G. (2024). Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline. Alzh Dement-Dadm16. 10.1002/dad2.12510.
- Upadhyay, N., Spottke, A., Schneider, A., Hoffmann, D.C., Frommann, I., Ballarini, T., Fliessbach, K., Bender, B., Heekeren, H.R., Haynes, J.D., Ewers, M., Duzel, E., Glanz, W., Dobisch, L., Buerger, K., Janowitz, D., Levin, J., Danek, A., Teipel, S., Kilimann, I., Synofzik, M., Wilke, C., Peters, O., Preis, L., Priller, J., Spruth, E.J., Jessen, F., and Boecker, H. (2024). Fronto-striatal alterations correlate with apathy severity in behavioral variant frontotemporal dementia. Brain Imaging Behav18, 66-72. 10.1007/s11682-023-00812-3.
- Vockert, N., Machts, J., Kleineidam, L., Nemali, A., Incesoy, E.I., Bernal, J., Schutze, H., Yakupov, R., Peters, O., Gref, D., Schneider, L.S., Preis, L., Priller, J., Spruth, E.J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Rostamzadeh, A., Glanz, W., Teipel, S., Kilimann, I., Goerss, D., Laske, C., Munk, M.H., Spottke, A., Roy, N., Heneka, M.T., Brosseron, F., Wagner, M., Wolfsgruber, S., Dobisch, L., Dechent, P., Hetzer, S., Scheffler, K., Zeidman, P., Stern, Y., Schott, B.H., Jessen, F., Duzel, E., Maass, A., Ziegler, G., and group, D.s. (2024). Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation. Nat Commun15, 9815. 10.1038/s41467-024-53360-9.
- Wang, X., Freiesleben, S.D., Schneider, L.S., Preis, L., Priller, J., Spruth, E.J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Hansen, N., Jessen, F., Rostamzadeh, A., Duzel, E., Glanz, W., Incesoy, E.I., Buerger, K., Janowitz, D., Ewers, M., Perneczky, R., Rauchmann, B.S., Teipel, S.J., Kilimann, I., Goerss, D., Laske, C., Munk, M.H.J., Spottke, A., Roy-Kluth, N., Heneka, M.T., Brosseron, F., Wagner, M., Wolfsgruber, S., Ramirez, A., Kleineidam, L., Stark, M., and Peters, O. (2024). Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline. Neurology103, e209806. 10.1212/WNL.0000000000209806.
Hamid Kashkar
- Injarabian, L., Willenborg, S., Welcker, D., Sanin, D.E., Pasparakis, M., Kashkar, H., and Eming, S.A. (2024). FADD- and RIPK3-Mediated Cell Death Ensures Clearance of Ly6C(high) Wound Macrophages from Damaged Tissue. J Invest Dermatol144, 152-164 e157. 10.1016/j.jid.2023.06.203.
Peter Kloppenburg
- De Solis, A.J., Del Rio-Martin, A., Radermacher, J., Chen, W., Steuernagel, L., Bauder, C.A., Eggersmann, F.R., Morgan, D.A., Cremer, A.L., Sue, M., Germer, M., Kukat, C., Vollmar, S., Backes, H., Rahmouni, K., Kloppenburg, P., and Bruning, J.C. (2024). Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism. Nat Metab6, 473-493. 10.1038/s42255-024-00987-z.
- Sotelo-Hitschfeld, T., Minere, M., Klemm, P., Borgmann, D., Wnuk-Lipinski, D., Jais, A., Jia, X., Corneliussen, S., Kloppenburg, P., Fenselau, H., and Bruning, J.C. (2024). GABAergic disinhibition from the BNST to PNOC(ARC) neurons promotes HFD-induced hyperphagia. Cell Rep43, 114343. 10.1016/j.celrep.2024.114343.
- Zhou, X., Stine, C., Prada, P.O., Fusca, D., Assoumou, K., Dernic, J., Bhat, M.A., Achanta, A.S., Johnson, J.C., Pasqualini, A.L., Jadhav, S., Bauder, C.A., Steuernagel, L., Ravotto, L., Benke, D., Weber, B., Suko, A., Palmiter, R.D., Stoeber, M., Kloppenburg, P., Bruning, J.C., Bruchas, M.R., and Patriarchi, T. (2024). Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release. Nat Commun15, 5353. 10.1038/s41467-024-49712-0.
Natalia Kononenko
- Camblor-Perujo, S., Ozer Yildiz, E., Kupper, H., Overhoff, M., Rastogi, S., Bazzi, H., and Kononenko, N.L. (2024). The AP-2 complex interacts with gamma-TuRC and regulates the proliferative capacity of neural progenitors. Life Sci Alliance7. 10.26508/lsa.202302029.
Tatiana Korotkova
- Altafi, M., Chen, C., Korotkova, T., and Ponomarenko, A. (2024). Sequential Activation of Lateral Hypothalamic Neuronal Populations during Feeding and Their Assembly by Gamma Oscillations. J Neurosci44. 10.1523/JNEUROSCI.0518-24.2024.
- Chen, C., Altafi, M., Corbu, M.A., Trenk, A., van den Munkhof, H., Weineck, K., Bender, F., Carus-Cadavieco, M., Bakhareva, A., Korotkova, T., and Ponomarenko, A. (2024). The dynamic state of a prefrontal-hypothalamic-midbrain circuit commands behavioral transitions. Nat Neurosci27, 952-963. 10.1038/s41593-024-01598-3.
- Lubomirov, L.T., Weber, G., Schroeter, M., Metzler, D., Bust, M., Korotkova, T., Hescheler, J., Todorov, V.T., Pfitzer, G., and Grisk, O. (2025). Alanine mutation of the targeting subunit of the myosin phosphatase, MYPT1 at threonine 696 reduces cGMP responsiveness of mouse femoral arteries. Eur J Pharmacol986, 177133. 10.1016/j.ejphar.2024.177133.
Peter Kreuzaler
- Chen, Y.G., Rieser, E., Bhamra, A., Surinova, S., Kreuzaler, P., Ho, M.H., Tsai, W.C., Peltzer, N., de Miguel, D., and Walczak, H. (2024). LUBAC enables tumor-promoting LTbeta receptor signaling by activating canonical NF-kappaB. Cell Death Differ31, 1267-1284. 10.1038/s41418-024-01355-w.
Thomas Krieg
- Hassan, N., Krieg, T., Kopp, A., Bach, A.D., and Kroger, N. (2024). Challenges and Pitfalls of Research Designs Involving Magnesium-Based Biomaterials: An Overview. Int J Mol Sci25. 10.3390/ijms25116242.
- Kernich, N., Peters, F., Schreml, J., Semler, O., Koch, M., Schonau, E., Huntgeburth, M., Eysel, P., Krieg, T., von Stebut-Borschitz, E., and Tantcheva-Poor, I. (2024). Ehlers-Danlos Syndromes and Related Disorders: Diagnostic Challenges and the Need for an Interdisciplinary Patient Care in Germany. Dermatology10.1159/000542026, 1-9. 10.1159/000542026.
- Knobler, R., Geroldinger-Simic, M., Kreuter, A., Hunzelmann, N., Moinzadeh, P., Rongioletti, F., Denton, C., Mouthon, L., Cutolo, M., Smith, V., Gabrielli, A., Bagot, M., Olesen, A.B., Foeldvari, I., Jalili, A., Kahari, V.M., Karpati, S., Kofoed, K., Olszewska, M., Panelius, J., Quaglino, P., Seneschal, J., Sticherling, M., Sunderkotter, C., Tanew, A., Wolf, P., Worm, M., Skrok, A., Rudnicka, L., and Krieg, T. (2024). Consensus statement on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxoedema and scleroedema. J Eur Acad Dermatol Venereol38, 1281-1299. 10.1111/jdv.19937.
- Kreuter, A., Moinzadeh, P., Kinberger, M., Horneff, G., Worm, M., Werner, R.N., Hammacher, A., Krieg, T., Wenzel, J., Oeschger, M., Weibel, L., Mullegger, R., and Hunzelmann, N. (2024). S2k guideline: Diagnosis and therapy of localized scleroderma. J Dtsch Dermatol Ges22, 605-620. 10.1111/ddg.15328.
- Raote, I., Rosendahl, A.H., Hakkinen, H.M., Vibe, C., Kucukaylak, I., Sawant, M., Keufgens, L., Frommelt, P., Halwas, K., Broadbent, K., Cunquero, M., Castro, G., Villemeur, M., Nuchel, J., Bornikoel, A., Dam, B., Zirmire, R.K., Kiran, R., Carolis, C., Andilla, J., Loza-Alvarez, P., Ruprecht, V., Jamora, C., Campelo, F., Kruger, M., Hammerschmidt, M., Eckes, B., Neundorf, I., Krieg, T., and Malhotra, V. (2024). TANGO1 inhibitors reduce collagen secretion and limit tissue scarring. Nat Commun15, 3302. 10.1038/s41467-024-47004-1.
- Reiter, L., Niehoff, N., Weiland, D., Helbig, D., Eming, S.A., Krieg, T., Etich, J., Brachvogel, B., Wiesner, R.J., and Knuever, J. (2024). Mitochondrial DNA mutations attenuate Bleomycin-induced dermal fibrosis by inhibiting differentiation into myofibroblasts. Matrix Biol132, 72-86. 10.1016/j.matbio.2024.07.002.
- Roop, D.R., Krieg, T., Werner, S., Yuspa, S., Diehl, K., Seervai, R., Harris-Tryon, T., and Leachman, S.A. (2024). Montagna Symposium on the Biology of Skin 70(th) Anniversary: Visualizing the Future! J Invest Dermatol144, 2120-2124. 10.1016/j.jid.2024.04.001.
- Schiavinato, A., Marcous, F., Zuk, A.V., Keene, D.R., Tufa, S.F., Mosquera, L.M., Zigrino, P., Mauch, C., Eckes, B., Francois, K., De Backer, J., Hunzelmann, N., Moinzadeh, P., Krieg, T., Callewaert, B., and Sengle, G. (2024). New insights into the structural role of EMILINs within the human skin microenvironment. Sci Rep14, 30345. 10.1038/s41598-024-81509-5.
Marcus Krüger
- Abdelfattah, F., Schulz, H., Wehland, M., Corydon, T.J., Sahana, J., Kraus, A., Krüger, M., Gonzalez-Torres, L.F., Cortes-Sanchez, J.L., Wise, P.M., Mushunuri, A., Hemmersbach, R., Liemersdorf, C., Infanger, M., and Grimm, D. (2024). Omics Studies of Specialized Cells and Stem Cells under Microgravity Conditions. Int J Mol Sci25. 10.3390/ijms251810014.
- Andrysiak, K., Ferdek, P.E., Sanetra, A.M., Machaj, G., Schmidt, L., Kraszewska, I., Sarad, K., Palus-Chramiec, K., Lis, O., Targosz-Korecka, M., Krüger, M., Lewandowski, M.H., Ylla, G., Stepniewski, J., and Dulak, J. (2024). Upregulation of utrophin improves the phenotype of Duchenne muscular dystrophy hiPSC-derived CMs. Mol Ther Nucleic Acids35, 102247. 10.1016/j.omtn.2024.102247.
- Andrysiak, K., Machaj, G., Priesmann, D., Woznicka, O., Martyniak, A., Ylla, G., Krüger, M., Pyza, E., Potulska-Chromik, A., Kostera-Pruszczyk, A., Loboda, A., Stepniewski, J., and Dulak, J. (2024). Dysregulated iron homeostasis in dystrophin-deficient cardiomyocytes: correction by gene editing and pharmacological treatment. Cardiovasc Res120, 69-81. 10.1093/cvr/cvad182.
- Beielstein, A.C., Izquierdo, E., Blakemore, S., Nickel, N., Michalik, M., Chawan, S., Brinker, R., Bartel, H.H., Vorholt, D., Albert, L., Nolte, J.L., Linke, R., Costa Picossi, C.R., Saiz, J., Picard, F., Florin, A., Meinel, J., Buttner, R., Diefenhardt, P., Brahler, S., Villasenor, A., Winkels, H., Hallek, M., Krüger, M., Barbas, C., and Pallasch, C.P. (2024). Macrophages are activated toward phagocytic lymphoma cell clearance by pentose phosphate pathway inhibition. Cell Rep Med5, 101830. 10.1016/j.xcrm.2024.101830.
- Chopra, S., Kadiri, O.L., Ulke, J., Hauffe, R., Jonas, W., Cheshmeh, S., Schmidt, L., Bishop, C.A., Yagoub, S., Schell, M., Rath, M., Kruger, J., Lippert, R.N., Krüger, M., Kappert, K., and Kleinridders, A. (2024). DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways. Cell Rep43, 114984. 10.1016/j.celrep.2024.114984.
- Das, A., Thapa, P., Santiago, U., Shanmugam, N., Banasiak, K., Dazbrowska, K., Nolte, H., Szulc, N.A., Gathungu, R.M., Cysewski, D., Krueger, M., Dadlez, M., Nowotny, M., Camacho, C.J., Hoppe, T., and Pokrzywa, W. (2024). Author Correction: A heterotypic assembly mechanism regulates CHIP E3 ligase activity. EMBO J43, 1110-1111. 10.1038/s44318-024-00042-3.
- Geissen, S., Braumann, S., Adler, J., Nettersheim, F.S., Mehrkens, D., Hof, A., Guthoff, H., von Stein, P., Witkowski, S., Gerdes, N., Tellkamp, F., Krüger, M., Isermann, L., Trifunovic, A., Bunck, A.C., Mollenhauer, M., Winkels, H., Adam, M., Klinke, A., Buch, G., Ten Cate, V., Hellmich, M., Kelm, M., Rudolph, V., Wild, P.S., Rosenkranz, S., and Baldus, S. (2024). Inhibition of myeloperoxidase to treat left ventricular dysfunction in non-ischaemic cardiomyopathy. Eur J Heart Fail26, 2269-2281. 10.1002/ejhf.3435.
- Gomez, J.M., Nolte, H., Vogelsang, E., Dey, B., Takeda, M., Giudice, G., Faxel, M., Haunold, T., Cepraga, A., Zinzen, R.P., Krüger, M., Petsalaki, E., Wang, Y.C., and Leptin, M. (2024). Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo. Elife13. 10.7554/eLife.99263.
- In 't Groen, S.L.M., Franken, M., Bock, T., Krüger, M., de Greef, J.C., and Pijnappel, W. (2024). A knock down strategy for rapid, generic, and versatile modelling of muscular dystrophies in 3D-tissue-engineered-skeletal muscle. Skelet Muscle14, 3. 10.1186/s13395-024-00335-5.
- Koyuncu, S., Loureiro, R., Lee, H.J., Wagle, P., Krueger, M., and Vilchez, D. (2024). Author Correction: Rewiring of the ubiquitinated proteome determines ageing in C. elegans. Nature626, E20. 10.1038/s41586-024-07168-8.
- Kraszewska, I., Sarad, K., Andrysiak, K., Kopacz, A., Schmidt, L., Krüger, M., Dulak, J., and Jazwa-Kusior, A. (2024). Casein kinase 2 activity is a host restriction factor for AAV transduction. Mol Ther32, 84-102. 10.1016/j.ymthe.2023.11.010.
- Moschandrea, C., Kondylis, V., Evangelakos, I., Herholz, M., Schneider, F., Schmidt, C., Yang, M., Ehret, S., Heine, M., Jaeckstein, M.Y., Szczepanowska, K., Schwarzer, R., Baumann, L., Bock, T., Nikitopoulou, E., Brodesser, S., Krüger, M., Frezza, C., Heeren, J., Trifunovic, A., and Pasparakis, M. (2024). Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes. Nature625, 385-392. 10.1038/s41586-023-06857-0.
- Raote, I., Rosendahl, A.H., Hakkinen, H.M., Vibe, C., Kucukaylak, I., Sawant, M., Keufgens, L., Frommelt, P., Halwas, K., Broadbent, K., Cunquero, M., Castro, G., Villemeur, M., Nuchel, J., Bornikoel, A., Dam, B., Zirmire, R.K., Kiran, R., Carolis, C., Andilla, J., Loza-Alvarez, P., Ruprecht, V., Jamora, C., Campelo, F., Krüger, M., Hammerschmidt, M., Eckes, B., Neundorf, I., Krieg, T., and Malhotra, V. (2024). TANGO1 inhibitors reduce collagen secretion and limit tissue scarring. Nat Commun15, 3302. 10.1038/s41467-024-47004-1.
- Schmidt, L., Saynisch, M., Hoegsbjerg, C., Schmidt, A., Mackey, A., Lackmann, J.W., Muller, S., Koch, M., Brachvogel, B., Kjaer, M., Antczak, P., and Krüger, M. (2024). Spatial proteomics of skeletal muscle using thin cryosections reveals metabolic adaptation at the muscle-tendon transition zone. Cell Rep43, 114374. 10.1016/j.celrep.2024.114374.
- Veronese, M., Kallabis, S., Kaczmarek, A.T., Das, A., Robers, L., Schumacher, S., Lofrano, A., Brodesser, S., Muller, S., Hofmann, K., Krüger, M., and Rugarli, E.I. (2024). ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway. Life Sci Alliance7. 10.26508/lsa.202402620.
Thomas Langer
- Ahola, S., and Langer, T. (2024). Ferroptosis in mitochondrial cardiomyopathy. Trends Cell Biol34, 150-160. 10.1016/j.tcb.2023.06.002.
- Ahola, S., Pazurek, L.A., Mayer, F., Lampe, P., Hermans, S., Becker, L., Amarie, O.V., Fuchs, H., Gailus-Durner, V., de Angelis, M.H., Riedel, D., Nolte, H., and Langer, T. (2024). Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy. Sci Adv10, eadp0443. 10.1126/sciadv.adp0443.
- Baker, M.J., Blau, K.U., Anderson, A.J., Palmer, C.S., Fielden, L.F., Crameri, J.J., Milenkovic, D., Thorburn, D.R., Frazier, A.E., Langer, T., and Stojanovski, D. (2024). CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. J Cell Biol223. 10.1083/jcb.202305087.
- Delgado de la Herran, H., Vecellio Reane, D., Cheng, Y., Katona, M., Hosp, F., Greotti, E., Wettmarshausen, J., Patron, M., Mohr, H., Prudente de Mello, N., Chudenkova, M., Gorza, M., Walia, S., Feng, M.S., Leimpek, A., Mielenz, D., Pellegata, N.S., Langer, T., Hajnoczky, G., Mann, M., Murgia, M., and Perocchi, F. (2024). Systematic mapping of mitochondrial calcium uniporter channel (MCUC)-mediated calcium signaling networks. EMBO J43, 5288-5326. 10.1038/s44318-024-00219-w.
- Henschke, S., Nolte, H., Magoley, J., Kleele, T., Brandt, C., Hausen, A.C., Wunderlich, C.M., Bauder, C.A., Aschauer, P., Manley, S., Langer, T., Wunderlich, F.T., and Bruning, J.C. (2024). Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver. Science384, 438-446. 10.1126/science.adk1005.
- Sawczyc, H., Tatsuta, T., Oster, C., Kosteletos, S., Lange, S., Bohg, C., Langer, T., and Lange, A. (2024). Lipid-polymer nanoparticles to probe the native-like environment of intramembrane rhomboid protease GlpG and its activity. Nat Commun15, 7533. 10.1038/s41467-024-51989-0.
- Zaninello, M., Schlegel, T., Nolte, H., Pirzada, M., Savino, E., Barth, E., Klein, I., Wustenberg, H., Uddin, T., Wolff, L., Wirth, B., Lehmann, H.C., Cioni, J.M., Langer, T., and Rugarli, E.I. (2024). CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy. Sci Adv10, eadn2050. 10.1126/sciadv.adn2050.
Marius Lemberg
- Avci, D., Heidasch, R., Costa, M., Luchtenborg, C., Kale, D., Brugger, B., and Lemberg, M.K. (2024). Intramembrane protease SPP defines a cholesterol-regulated abundance control of the mevalonate pathway enzyme squalene synthase. J Biol Chem300, 105644. 10.1016/j.jbc.2024.105644.
- Engberg, O., Mathath, A.V., Dobel, V., Frie, C., Lemberg, M.K., Chakraborty, D., and Huster, D. (2024). Evaluating the impact of the membrane thickness on the function of the intramembrane protease GlpG. Biophys J123, 4067-4081. 10.1016/j.bpj.2024.10.019.
- Knopf, J.D., Steigleder, S.S., Korn, F., Kuhnle, N., Badenes, M., Tauber, M., Theobald, S.J., Rybniker, J., Adrain, C., and Lemberg, M.K. (2024). RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling. Nat Commun15, 1528. 10.1038/s41467-024-45615-2.
- Link, C.J., Marques, O., Knopf, J.D., Lemberg, M.K., and Muckenthaler, M.U. (2024). E3 ubiquitin ligases SMURF1 and HECW1 regulate hepcidin-induced degradation of ferroportin in HeLa cells. Biochim Biophys Acta Mol Cell Res1871, 119803. 10.1016/j.bbamcr.2024.119803.
- Sergejevs, N., Avci, D., van de Weijer, M.L., Corey, R.A., Lemberg, M.K., and Carvalho, P. (2024). Topology surveillance of the lanosterol demethylase CYP51A1 by signal peptide peptidase. J Cell Sci137. 10.1242/jcs.262333.
Ivan Matic
- Longarini, E.J., and Matic, I. (2024). Preserving ester-linked modifications reveals glutamate and aspartate mono-ADP-ribosylation by PARP1 and its reversal by PARG. Nat Commun15, 4239. 10.1038/s41467-024-48314-0.
- Rack, J.G.M., Voorneveld, J., Longarini, E.J., Wijngaarden, S., Zhu, K., Peters, A., Sia, J.J., Prokhorova, E., Ahel, D., Matic, I., Filippov, D.V., and Ahel, I. (2024). Reversal of tyrosine-linked ADP-ribosylation by ARH3 and PARG. J Biol Chem300, 107838. 10.1016/j.jbc.2024.107838.
- Mukherjee, R., Bhattacharya, A., Mello-Vieira, J., Kuncha, S.K., Hoffmann, M., Gonzalez, A., Rathore, R., Chadha, A., Shin, D., Colby, T., Matic, I., Mukherjee, S., Misra, M., and Dikic, I. (2025). Serine ubiquitination of SQSTM1 regulates NFE2L2-dependent redox homeostasis. Autophagy21, 407-423. 10.1080/15548627.2024.2404375.
To top
Elisa Motori
- Filograna, R., Gerlach, J., Choi, H.N., Rigoni, G., Barbaro, M., Oscarson, M., Lee, S., Tiklova, K., Ringner, M., Koolmeister, C., Wibom, R., Riggare, S., Nennesmo, I., Perlmann, T., Wredenberg, A., Wedell, A., Motori, E., Svenningsson, P., and Larsson, N.G. (2024). PARKIN is not required to sustain OXPHOS function in adult mammalian tissues. Npj Parkinsons Dis10, 93. 10.1038/s41531-024-00707-0.
- Franchino, C.A., Motori, E., and Bergami, M. (2024). Janus-faced Mitofusin 2 (MFN2): mitochondria-endoplasmic reticulum shaping and tethering functions unveiled. Signal Transduct Target Ther9, 4. 10.1038/s41392-023-01730-y.
To top
Roman-Ulrich Müller
- Arjune, S., Lettenmeier, K., Todorova, P., Spath, M.R., Majjouti, M., Mahabir, E., Grundmann, F., and Muller, R.U. (2024). Inflammatory Cytokine Levels in Patients with Autosomal Dominant Polycystic Kidney Disease. Kidney3605, 1289-1298. 10.34067/KID.0000000000000525.
- Arjune, S., Spath, M.R., Oehm, S., Todorova, P., Schunk, S.J., Lettenmeier, K., Chon, S.H., Bartram, M.P., Antczak, P., Grundmann, F., Fliser, D., and Muller, R.U. (2024). DKK3 as a potential novel biomarker in patients with autosomal polycystic kidney disease. Clin Kidney J17, sfad262. 10.1093/ckj/sfad262.
- Bais, T., Meijer, E., Kramers, B.J., Vart, P., Vervloet, M., Salih, M., Bammens, B., Demoulin, N., Todorova, P., Muller, R.U., Halbritter, J., Paliege, A., Gall, E.C., Knebelmann, B., Torra, R., Ong, A.C.M., Karet Frankl, F.E., and Gansevoort, R.T. (2024). HYDROchlorothiazide versus placebo to PROTECT polycystic kidney disease patients and improve their quality of life: study protocol and rationale for the HYDRO-PROTECT randomized controlled trial. Trials25, 120. 10.1186/s13063-024-07952-x.
- Hauser, D., Urda, L., Lang, C., Mittelholzer, C., Otte, F., Kipfer, E., Zhang, Y., Lett, M., Schebitz, C., Muller, R.U., Klimkait, W., and Klimkait, T. (2024). Benefits of Repeated SARS-CoV-2 Vaccination and Virus-induced Cross-neutralization Potential in Immunocompromised Transplant Patients and Healthy Individuals. Open Forum Infect Dis11, ofae527. 10.1093/ofid/ofae527.
- Knol, M.G.E., Wulfmeyer, V.C., Muller, R.U., and Rinschen, M.M. (2024). Amino acid metabolism in kidney health and disease. Nat Rev Nephrol20, 771-788. 10.1038/s41581-024-00872-8.
- Koehler, F.C., Spath, M.R., Meyer, A.M., and Muller, R.U. (2024). Fueling the success of transplantation through nutrition: recent insights into nutritional interventions, their interplay with gut microbiota and cellular mechanisms. Curr Opin Organ Transplant29, 284-293. 10.1097/MOT.0000000000001159.
- Mekahli, D., Muller, R.U., Marlais, M., Wlodkowski, T., Haeberle, S., de Argumedo, M.L., Bergmann, C., Breysem, L., Fladrowski, C., Henske, E.P., Janssens, P., Jouret, F., Kingswood, J.C., Lattouf, J.B., Lilien, M., Maleux, G., Rozenberg, M., Siemer, S., Devuyst, O., Schaefer, F., Kwiatkowski, D.J., Rouviere, O., and Bissler, J. (2024). Clinical practice recommendations for kidney involvement in tuberous sclerosis complex: a consensus statement by the ERKNet Working Group for Autosomal Dominant Structural Kidney Disorders and the ERA Genes & Kidney Working Group. Nat Rev Nephrol20, 402-420. 10.1038/s41581-024-00818-0.
- Rroji, M., Kasa, M., Spahia, N., Spasovski, G., and Muller, R.U. (2024). Familial renal glycosuria as a genetic model of long-term SGLT2 inhibition: potential implications for calcium phosphate metabolism and bone health. J Nephrol10.1007/s40620-024-02164-7. 10.1007/s40620-024-02164-7.
- Schmidt, J., Arjune, S., Boehm, V., Grundmann, F., Muller, R.U., and Antczak, P. (2024). Bridging health registry data acquisition and real-time data analytics. Front Med (Lausanne)11, 1430676. 10.3389/fmed.2024.1430676.
- Schonauer, R., Sierks, D., Boerrigter, M., Jawaid, T., Caroff, L., Audrezet, M.P., Friedrich, A., Shaw, M., Degenhardt, J., Forberger, M., de Fallois, J., Blaker, H., Bergmann, C., Godiker, J., Schindler, P., Schlevogt, B., Muller, R.U., Berg, T., Patterson, I., Griffiths, W.J., Sayer, J.A., Genomics England Research, C., Popp, B., Torres, V.E., Hogan, M.C., Somlo, S., Watnick, T.J., Nevens, F., Besse, W., Cornec-Le Gall, E., Harris, P.C., Drenth, J.P.H., and Halbritter, J. (2024). Sex, Genotype, and Liver Volume Progression as Risk of Hospitalization Determinants in Autosomal Dominant Polycystic Liver Disease. Gastroenterology166, 902-914. 10.1053/j.gastro.2023.12.007.
- Trappe, M., Affeldt, P., Grundmann, F., Kann, M., Koehler, F.C., Muller, R.U., Stippel, D., Kaiser, R., Knops, E., Heger, E., Steger, G., Klein, F., Kurschat, C., and Di Cristanziano, V. (2024). Five-year single-center analysis of cytomegalovirus viremia in kidney transplant recipients and possible implication for novel prophylactic therapy approaches. Transpl Infect Dis26, e14233. 10.1111/tid.14233.
- van Heugten, M.H., Blijdorp, C.J., Arjune, S., van Willigenburg, H., Bezstarosti, K., Demmers, J.A.A., Musterd-Bhaggoe, U., Meijer, E., Gansevoort, R.T., Zietse, R., Hayat, S., Kramann, R., Muller, R.U., Salih, M., Hoorn, E.J., and Consortium, D. (2024). Matrix Metalloproteinase-7 in Urinary Extracellular Vesicles Identifies Rapid Disease Progression in Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol35, 321-334. 10.1681/ASN.0000000000000277.
Carien Niessen
- Kasper, J.Y., Laschke, M.W., Koch, M., Alibardi, L., Magin, T., Niessen, C.M., and Del Campo, A. (2024). Actin-templated Structures: Nature's Way to Hierarchical Surface Patterns (Gecko's Setae as Case Study). Adv Sci (Weinh)11, e2303816. 10.1002/advs.202303816.
- McCreery, K.P., Stubb, A., Stephens, R., Fursova, N.A., Cook, A., Kruse, K., Michelbach, A., Biggs, L.C., Keikhosravi, A., Nykanen, S., Hyden-Granskog, C., Zou, J., Lackmann, J.W., Niessen, C.M., Vuoristo, S., Miroshnikova, Y.A., and Wickstrom, S.A. (2024). Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells. bioRxiv10.1101/2024.09.07.611779. 10.1101/2024.09.07.611779.
- Niessen, C.M., Manning, M.L., and Wickstrom, S.A. (2024). Mechanochemical Principles of Epidermal Tissue Dynamics. Cold Spring Harb Perspect Biol10.1101/cshperspect.a041518. 10.1101/cshperspect.a041518.
- Titze, V.M., Caixeiro, S., Dinh, V.S., Konig, M., Rubsam, M., Pathak, N., Schumacher, A.L., Germer, M., Kukat, C., Niessen, C.M., Schubert, M., and Gather, M.C. (2024). Hyperspectral confocal imaging for high-throughput readout and analysis of bio-integrated microlasers. Nat Protoc19, 928-959. 10.1038/s41596-023-00924-6.
- Wibbe, N., Steinbacher, T., Tellkamp, F., Beckmann, N., Brinkmann, F., Stecher, M., Gerke, V., Niessen, C.M., and Ebnet, K. (2024). RhoGDI1 regulates cell-cell junctions in polarized epithelial cells. Front Cell Dev Biol12, 1279723. 10.3389/fcell.2024.1279723
Maria Notara
- Hopkinson, A., Notara, M., Cursiefen, C., and Sidney, L.E. (2024). Increased Anti-Inflammatory Therapeutic Potential and Progenitor Marker Expression of Corneal Mesenchymal Stem Cells Cultured in an Optimized Propagation Medium. Cell Transplant33, 9636897241241992. 10.1177/09636897241241992.
- Meshko, B., Volatier, T.L.A., Mann, J., Kluth, M.A., Ganss, C., Frank, M.H., Frank, N.Y., Ksander, B.R., Cursiefen, C., and Notara, M. (2024). Anti-Inflammatory and Anti-(Lymph)angiogenic Properties of an ABCB5+ Limbal Mesenchymal Stem Cell Population. Int J Mol Sci25. 10.3390/ijms25179702.
- Oda, H., Manthiram, K., Chavan, P.P., Rieser, E., Veli, O., Kaya, O., Rauch, C., Nakabo, S., Kuehn, H.S., Swart, M., Wang, Y., Celik, N.I., Molitor, A., Ziaee, V., Movahedi, N., Shahrooei, M., Parvaneh, N., Alipour-Olyei, N., Carapito, R., Xu, Q., Preite, S., Beck, D.B., Chae, J.J., Nehrebecky, M., Ombrello, A.K., Hoffmann, P., Romeo, T., Deuitch, N.T., Matthiasardottir, B., Mullikin, J., Komarow, H., Stoddard, J., Niemela, J., Dobbs, K., Sweeney, C.L., Anderton, H., Lawlor, K.E., Yoshitomi, H., Yang, D., Boehm, M., Davis, J., Mudd, P., Randazzo, D., Tsai, W.L., Gadina, M., Kaplan, M.J., Toguchida, J., Mayer, C.T., Rosenzweig, S.D., Notarangelo, L.D., Iwai, K., Silke, J., Schwartzberg, P.L., Boisson, B., Casanova, J.L., Bahram, S., Rao, A.P., Peltzer, N., Walczak, H., Lalaoui, N., Aksentijevich, I., and Kastner, D.L. (2024). Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency. Nat Immunol25, 764-777. 10.1038/s41590-024-01817-w.
- van Velthoven, A.J.H., Utheim, T.P., Notara, M., Bremond-Gignac, D., Figueiredo, F.C., Skottman, H., Aberdam, D., Daniels, J.T., Ferrari, G., Grupcheva, C., Koppen, C., Parekh, M., Ritter, T., Romano, V., Ferrari, S., Cursiefen, C., Lagali, N., LaPointe, V.L.S., and Dickman, M.M. (2024). Corrigendum to "Future directions in managing aniridia-associated keratopathy" [Surv Ophthalmol 68 (2023) 940-956]. Surv Ophthalmol69, 300-301. 10.1016/j.survophthal.2024.01.001.
- Volatier, T., Cursiefen, C., and Notara, M. (2024). Current Advances in Corneal Stromal Stem Cell Biology and Therapeutic Applications. Cells13. 10.3390/cells13020163.
Hirotsugu Oda
- Oda, H., Manthiram, K., Chavan, P.P., Rieser, E., Veli, O., Kaya, O., Rauch, C., Nakabo, S., Kuehn, H.S., Swart, M., Wang, Y., Celik, N.I., Molitor, A., Ziaee, V., Movahedi, N., Shahrooei, M., Parvaneh, N., Alipour-Olyei, N., Carapito, R., Xu, Q., Preite, S., Beck, D.B., Chae, J.J., Nehrebecky, M., Ombrello, A.K., Hoffmann, P., Romeo, T., Deuitch, N.T., Matthiasardottir, B., Mullikin, J., Komarow, H., Stoddard, J., Niemela, J., Dobbs, K., Sweeney, C.L., Anderton, H., Lawlor, K.E., Yoshitomi, H., Yang, D., Boehm, M., Davis, J., Mudd, P., Randazzo, D., Tsai, W.L., Gadina, M., Kaplan, M.J., Toguchida, J., Mayer, C.T., Rosenzweig, S.D., Notarangelo, L.D., Iwai, K., Silke, J., Schwartzberg, P.L., Boisson, B., Casanova, J.L., Bahram, S., Rao, A.P., Peltzer, N., Walczak, H., Lalaoui, N., Aksentijevich, I., and Kastner, D.L. (2024). Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency. Nat Immunol25, 764-777. 10.1038/s41590-024-01817-w.
Stephanie Panier
- Panier, S., Wang, S., and Schumacher, B. (2024). Genome Instability and DNA Repair in Somatic and Reproductive Aging. Annu Rev Pathol19, 261-290. 10.1146/annurev-pathmechdis-051122-093128.
- Wagener, R., Brandes, D., Jung, M., Huetzen, M.A., Bergmann, A.K., Panier, S., Picard, D., Fischer, U., Jachimowicz, R.D., Borkhardt, A., and Brozou, T. (2024). Optical genome mapping identifies structural variants in potentially new cancer predisposition candidate genes in pediatric cancer patients. Int J Cancer154, 607-614. 10.1002/ijc.34721.
Linda Partridge
- Baghdadi, M., Nespital, T., Monzo, C., Deelen, J., Gronke, S., and Partridge, L. (2024). Intermittent rapamycin feeding recapitulates some effects of continuous treatment while maintaining lifespan extension. Mol Metab10.1016/j.molmet.2024.101902, 101902. 10.1016/j.molmet.2024.101902.
- Papantonis, A., Antebi, A., Partridge, L., and Beyer, A. (2024). Age-associated changes in transcriptional elongation and their effects on homeostasis. Trends Cell Biol10.1016/j.tcb.2024.11.005. 10.1016/j.tcb.2024.11.005.
- Urena, E., Xu, B., Regan, J.C., Atilano, M.L., Minkley, L.J., Filer, D., Lu, Y.X., Bolukbasi, E., Khericha, M., Alic, N., and Partridge, L. (2024). Trametinib ameliorates aging-associated gut pathology in Drosophila females by reducing Pol III activity in intestinal stem cells. Proc Natl Acad Sci U S A121, e2311313121. 10.1073/pnas.2311313121.
- Wang, H.L., Siow, R., Schmauck-Medina, T., Zhang, J., Sandset, P.M., Filshie, C., Lund, O., Partridge, L., Bergersen, L.H., Juel Rasmussen, L., Palikaras, K., Sotiropoulos, I., Storm-Mathisen, J., Rubinsztein, D.C., Spillantini, M.G., De Zeeuw, C.I., Watne, L.O., Vyhnalek, M., Veverova, K., Liang, K.X., Tavernarakis, N., Bohr, V.A., Yokote, K., Saarela, J., Nilsen, H., Gonos, E.S., Scheibye-Knudsen, M., Chen, G., Kato, H., Selbaek, G., Fladby, T., Nilsson, P., Simonsen, A., Aarsland, D., Lautrup, S., Ottersen, O.P., Cox, L.S., and Fang, E.F. (2024). Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies. J Gerontol A Biol Sci Med Sci79. 10.1093/gerona/glae029.
- Zhang, P., Catterson, J.H., Gronke, S., and Partridge, L. (2024). Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system. Nat Aging4, 491-509. 10.1038/s43587-024-00578-3.
Manolis Pasparakis
- Eren, R.O., Kaya, G.G., Schwarzer, R., and Pasparakis, M. (2024). IKKepsilon and TBK1 prevent RIPK1 dependent and independent inflammation. Nat Commun15, 130. 10.1038/s41467-023-44372-y.
- Imai, T., Lin, J., Kaya, G.G., Ju, E., Kondylis, V., Kelepouras, K., Liccardi, G., Kim, C., and Pasparakis, M. (2024). The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation. Immunity57, 1497-1513 e1496. 10.1016/j.immuni.2024.04.016.
- Injarabian, L., Willenborg, S., Welcker, D., Sanin, D.E., Pasparakis, M., Kashkar, H., and Eming, S.A. (2024). FADD- and RIPK3-Mediated Cell Death Ensures Clearance of Ly6C(high) Wound Macrophages from Damaged Tissue. J Invest Dermatol144, 152-164 e157. 10.1016/j.jid.2023.06.203.
- Koerner, L., Wachsmuth, L., Kumari, S., Schwarzer, R., Wagner, T., Jiao, H., and Pasparakis, M. (2024). ZBP1 causes inflammation by inducing RIPK3-mediated necroptosis and RIPK1 kinase activity-independent apoptosis. Cell Death Differ31, 938-953. 10.1038/s41418-024-01321-6.
- Moschandrea, C., Kondylis, V., Evangelakos, I., Herholz, M., Schneider, F., Schmidt, C., Yang, M., Ehret, S., Heine, M., Jaeckstein, M.Y., Szczepanowska, K., Schwarzer, R., Baumann, L., Bock, T., Nikitopoulou, E., Brodesser, S., Kruger, M., Frezza, C., Heeren, J., Trifunovic, A., and Pasparakis, M. (2024). Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes. Nature625, 385-392. 10.1038/s41586-023-06857-0.
- Nagata, M., Carvalho Schafer, Y., Wachsmuth, L., and Pasparakis, M. (2024). A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses. EMBO J43, 5037-5056. 10.1038/s44318-024-00238-7.
- Rosain, J., Le Voyer, T., Liu, X., Gervais, A., Polivka, L., Cederholm, A., Berteloot, L., Parent, A.V., Pescatore, A., Spinosa, E., Minic, S., Kiszewski, A.E., Tsumura, M., Thibault, C., Esnaola Azcoiti, M., Martinovic, J., Philippot, Q., Khan, T., Marchal, A., Charmeteau-De Muylder, B., Bizien, L., Deswarte, C., Hadjem, L., Fauvarque, M.O., Dorgham, K., Eriksson, D., Falcone, E.L., Puel, M., Unal, S., Geraldo, A., Le Floc'h, C., Li, H., Rheault, S., Muti, C., Bobrie-Moyrand, C., Welfringer-Morin, A., Fuleihan, R.L., Levy, R., Roelens, M., Gao, L., Materna, M., Pellegrini, S., Piemonti, L., Catherinot, E., Goffard, J.C., Fekkar, A., Sacko-Sow, A., Soudee, C., Boucherit, S., Neehus, A.L., Has, C., Hubner, S., Blanchard-Rohner, G., Amador-Borrero, B., Utsumi, T., Taniguchi, M., Tani, H., Izawa, K., Yasumi, T., Kanai, S., Migaud, M., Aubart, M., Lambert, N., Gorochov, G., Picard, C., Soudais, C., L'Honneur, A.S., Rozenberg, F., Milner, J.D., Zhang, S.Y., Vabres, P., Trpinac, D., Marr, N., Boddaert, N., Desguerre, I., Pasparakis, M., Miller, C.N., Poziomczyk, C.S., Abel, L., Okada, S., Jouanguy, E., Cheynier, R., Zhang, Q., Cobat, A., Beziat, V., Boisson, B., Steffann, J., Fusco, F., Ursini, M.V., Hadj-Rabia, S., Bodemer, C., Bustamante, J., Luche, H., Puel, A., Courtois, G., Bastard, P., Landegren, N., Anderson, M.S., and Casanova, J.L. (2024). Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases. J Exp Med221. 10.1084/jem.20231152.
- Veli, O., Kaya, O., Varanda, A.B., Hildebrandt, X., Xiao, P., Estornes, Y., Poggenberg, M., Wang, Y., Pasparakis, M., Bertrand, M.J.M., Walczak, H., Annibaldi, A., Cardozo, A.K., and Peltzer, N. (2024). RIPK1 is dispensable for cell death regulation in beta-cells during hyperglycemia. Mol Metab87, 101988. 10.1016/j.molmet.2024.101988.
- Zierden, M., Berghausen, E.M., Gnatzy-Feik, L., Millarg, C., Picard, F.S.R., Kiljan, M., Geissen, S., Polykratis, A., Zimmermann, L., Nies, R.J., Pasparakis, M., Baldus, S., Valasarajan, C., Pullamsetti, S.S., Winkels, H., Vantler, M., and Rosenkranz, S. (2024). Hematopoietic PI3Kdelta deficiency aggravates murine atherosclerosis through impairment of Tregs. Jci Insight9. 10.1172/jci.insight.155626.
- Onji, M., Sigl, V., Lendl, T., Novatchkova, M., Ullate-Agote, A., Andersson-Rolf, A., Kozieradzki, I., Koglgruber, R., Pai, T.P., Lichtscheidl, D., Nayak, K., Zilbauer, M., Carranza Garcia, N.A., Sievers, L.K., Falk-Paulsen, M., Cronin, S.J.F., Hagelkruys, A., Sawa, S., Osborne, L.C., Rosenstiel, P., Pasparakis, M., Ruland, J., Takayanagi, H., Clevers, H., Koo, B.K., and Penninger, J.M. (2025). RANK drives structured intestinal epithelial expansion during pregnancy. Nature637, 156-166. 10.1038/s41586-024-08284-1.
M. de las Nieves Peltzer
- Albert, M.C., Uranga-Murillo, I., Arias, M., De Miguel, D., Pena, N., Montinaro, A., Varanda, A.B., Theobald, S.J., Areso, I., Saggau, J., Koch, M., Liccardi, G., Peltzer, N., Rybniker, J., Hurtado-Guerrero, R., Merino, P., Monzon, M., Badiola, J.J., Reindl-Schwaighofer, R., Sanz-Pamplona, R., Cebollada-Solanas, A., Megyesfalvi, Z., Dome, B., Secrier, M., Hartmann, B., Bergmann, M., Pardo, J., and Walczak, H. (2024). Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality. Cell Death Differ31, 544-557. 10.1038/s41418-024-01278-6.
- Chen, Y.G., Rieser, E., Bhamra, A., Surinova, S., Kreuzaler, P., Ho, M.H., Tsai, W.C., Peltzer, N., de Miguel, D., and Walczak, H. (2024). LUBAC enables tumor-promoting LTbeta receptor signaling by activating canonical NF-kappaB. Cell Death Differ31, 1267-1284. 10.1038/s41418-024-01355-w.
- Oda, H., Manthiram, K., Chavan, P.P., Rieser, E., Veli, O., Kaya, O., Rauch, C., Nakabo, S., Kuehn, H.S., Swart, M., Wang, Y., Celik, N.I., Molitor, A., Ziaee, V., Movahedi, N., Shahrooei, M., Parvaneh, N., Alipour-Olyei, N., Carapito, R., Xu, Q., Preite, S., Beck, D.B., Chae, J.J., Nehrebecky, M., Ombrello, A.K., Hoffmann, P., Romeo, T., Deuitch, N.T., Matthiasardottir, B., Mullikin, J., Komarow, H., Stoddard, J., Niemela, J., Dobbs, K., Sweeney, C.L., Anderton, H., Lawlor, K.E., Yoshitomi, H., Yang, D., Boehm, M., Davis, J., Mudd, P., Randazzo, D., Tsai, W.L., Gadina, M., Kaplan, M.J., Toguchida, J., Mayer, C.T., Rosenzweig, S.D., Notarangelo, L.D., Iwai, K., Silke, J., Schwartzberg, P.L., Boisson, B., Casanova, J.L., Bahram, S., Rao, A.P., Peltzer, N., Walczak, H., Lalaoui, N., Aksentijevich, I., and Kastner, D.L. (2024). Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency. Nat Immunol25, 764-777. 10.1038/s41590-024-01817-w.
- Valdez Capuccino, L., Kleitke, T., Szokol, B., Svajda, L., Martin, F., Bonechi, F., Kreko, M., Azami, S., Montinaro, A., Wang, Y., Nikolov, V., Kaiser, L., Bonasera, D., Saggau, J., Scholz, T., Schmitt, A., Beleggia, F., Reinhardt, H.C., George, J., Liccardi, G., Walczak, H., Tovari, J., Bragelmann, J., Montero, J., Sos, M.L., Orfi, L., and Peltzer, N. (2024). CDK9 inhibition as an effective therapy for small cell lung cancer. Cell Death Dis15, 345. 10.1038/s41419-024-06724-4.
- Veli, O., Kaya, O., Varanda, A.B., Hildebrandt, X., Xiao, P., Estornes, Y., Poggenberg, M., Wang, Y., Pasparakis, M., Bertrand, M.J.M., Walczak, H., Annibaldi, A., Cardozo, A.K., and Peltzer, N. (2024). RIPK1 is dispensable for cell death regulation in beta-cells during hyperglycemia. Mol Metab87, 101988. 10.1016/j.molmet.2024.101988.
Lena Pernas
- Beros, S., and Pernas, L. (2024). Sleeping monsters: chronic infections in COVID-19 pathogenesis. Trends Microbiol32, 10-12. 10.1016/j.tim.2023.09.008.
- Delgado, J.M., and Pernas, L. (2024). Mitochondria as sensors of intracellular pathogens. Trends Endocrinol Metab10.1016/j.tem.2024.10.009. 10.1016/j.tem.2024.10.009.
- Garcia, B.M., Melchinger, P., Medeiros, T., Hendrix, S., Prabhu, K., Corrado, M., Kingma, J., Gorbatenko, A., Deshwal, S., Veronese, M., Scorrano, L., Pearce, E., Giavalisco, P., Zelcer, N., and Pernas, L. (2024). Glutamine sensing licenses cholesterol synthesis. EMBO J43, 5837-5856. 10.1038/s44318-024-00269-0.
- Kreimendahl, S., and Pernas, L. (2024). Metabolic immunity against microbes. Trends Cell Biol34, 496-508. 10.1016/j.tcb.2023.10.013.
Dominik Pesta
- Berwanger, C., Terres, D., Pesta, D., Eggers, B., Marcus, K., Wittig, I., Wiesner, R.J., Schroder, R., and Clemen, C.S. (2024). Immortalised murine R349P desmin knock-in myotubes exhibit a reduced proton leak and decreased ADP/ATP translocase levels in purified mitochondria. Eur J Cell Biol103, 151399. 10.1016/j.ejcb.2024.151399.
- Bodis, K., Breuer, S., Crepzia-Pevzner, A., Zaharia, O.P., Schon, M., Saatmann, N., Altenhofen, D., Springer, C., Szendroedi, J., Wagner, R., Al-Hasani, H., Roden, M., Pesta, D., Chadt, A., and Group, G.D.S. (2024). Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high-fat diet-fed mouse model. Diabetes Obes Metab26, 339-350. 10.1111/dom.15322.
- Buescher, F.M., Schmitz, M.T., Frett, T., Kramme, J., de Boni, L., Elmenhorst, E.M., Mulder, E., Moestl, S., Heusser, K., Frings-Meuthen, P., Jordan, J., Rittweger, J., and Pesta, D. (2024). Effects of 30 days bed rest and exercise countermeasures on PBMC bioenergetics. Acta Physiol10.1111/apha.14102. 10.1111/apha.14102.
- Carper, D., Lac, M., Coue, M., Labour, A., Martens, A., Banda, J.A.A., Mazeyrie, L., Mechta, M., Ingerslev, L.R., Elhadad, M., Petit, J.V., Maslo, C., Monbrun, L., Del Carmine, P., Sainte-Marie, Y., Bourlier, V., Laurens, C., Mithieux, G., Joanisse, D.R., Coudray, C., Feillet-Coudray, C., Montastier, E., Viguerie, N., Tavernier, G., Waldenberger, M., Peters, A., Wang-Sattler, R., Adamski, J., Suhre, K., Gieger, C., Kastenmuller, G., Illig, T., Lichtinghagen, R., Seissler, J., Mounier, R., Hiller, K., Jordan, J., Barres, R., Kuhn, M., Pesta, D., and Moro, C. (2024). Loss of atrial natriuretic peptide signaling causes insulin resistance, mitochondrial dysfunction, and low endurance capacity. Sci Adv10, eadl4374. 10.1126/sciadv.adl4374.
- Doerrier, C., Gama-Perez, P., Pesta, D., Distefano, G., Soendergaard, S.D., Chroeis, K.M., Gonzalez-Franquesa, A., Goodpaster, B.H., Prats, C., Sales-Pardo, M., Guimera, R., Coen, P.M., Gnaiger, E., Larsen, S., and Garcia-Roves, P.M. (2024). Harmonization of experimental procedures to assess mitochondrial respiration in human permeabilized skeletal muscle fibers. Free Radic Biol Med223, 384-397. 10.1016/j.freeradbiomed.2024.07.039.
- Hoenemann, J.N., Moestl, S., de Boni, L., Hoffmann, F., Arz, M., Berger, L., Pesta, D., Heusser, K., Mulder, E., Lee, S.M.C., Macias, B.R., Tank, J., and Jordan, J. (2024). Cardiopulmonary deconditioning and plasma volume loss are not sufficient to provoke orthostatic hypertension. Hypertens Res47, 2211-2216. 10.1038/s41440-024-01710-x.
- Leonhardt, T.P.M., Bristol, A., McLaurin, N., Forbes, S.C., Tanaka, H., Frings-Meuthen, P., Pesta, D., Rittweger, J., and Chilibeck, P.D. (2024). Dietary Intake of Athletes at the World Masters Athletics Championships as Assessed by Single 24 h Recall. Nutrients16. 10.3390/nu16040564.
- Pesta, D. (2024). Mitochondrial density in skeletal and cardiac muscle. Mitochondrion75, 101838. 10.1016/j.mito.2023.101838.
- Sarabhai, T., Kahl, S., Gancheva, S., Mastrototaro, L., Dewidar, B., Pesta, D., Ratter-Rieck, J.M., Bobrov, P., Jeruschke, K., Esposito, I., Schlensak, M., and Roden, M. (2024). Loss of mitochondrial adaptation associates with deterioration of mitochondrial turnover and structure in metabolic dysfunction-associated steatotic liver disease. Metabolism151, 155762. 10.1016/j.metabol.2023.155762.
- Speichinger, F., Gratl, A., Raude, B., Schawe, L., Carstens, J., Hering, N.A., Greiner, A., Pesta, D., and Frese, J.P. (2024). Mitochondrial respiration in peripheral arterial disease depends on stage severity. J Cell Mol Med28, e18126. 10.1111/jcmm.18126.
- Sarabhai, T., Kahl, S., Gancheva, S., Mastrototaro, L., Dewidar, B., Pesta, D., Ratter-Rieck, J.M., Bobrov, P., Jeruschke, K., Esposito, I., Schlensak, M., and Roden, M. (2025). Retraction notice "to Loss of mitochondrial adaptation associates with deterioration of mitochondrial turnover and structure in metabolic dysfunction-associated steatotic liver disease" [Metabolism 151 (2024) 155762]. Metabolism164, 156107. 10.1016/j.metabol.2024.156107.
Boris Pfander
- Galanti, L., Peritore, M., Gnugge, R., Cannavo, E., Heipke, J., Palumbieri, M.D., Steigenberger, B., Symington, L.S., Cejka, P., and Pfander, B. (2024). Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination. Nat Commun15, 2890. 10.1038/s41467-024-46951-z.
Christina Polidori
- Appel, K.S., Nurnberger, C., Bahmer, T., Forster, C., Polidori, M.C., Kohls, M., Kraus, T., Hettich-Damm, N., Petersen, J., Blaschke, S., Brohl, I., Butzmann, J., Dashti, H., Deckert, J., Dreher, M., Fiedler, K., Finke, C., Geisler, R., Hanses, F., Hopff, S.M., Jensen, B.O., Konik, M., Lehnert, K., de Miranda, S.M.N., Mitrov, L., Miljukov, O., Reese, J.P., Rohde, G., Scherer, M., Tausche, K., Tebbe, J.J., Vehreschild, J.J., Voit, F., Wagner, P., Weigl, M., Lemhofer, C., and Group, N.S. (2024). Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON). Infection52, 1813-1829. 10.1007/s15010-024-02226-9.
- Boccardi, V., Orr, M.E., Polidori, M.C., Ruggiero, C., and Mecocci, P. (2024). Focus on senescence: Clinical significance and practical applications. J Intern Med295, 599-619. 10.1111/joim.13775.
- Dunkel, A., von Storch, K., Hochheim, M., Zank, S., Polidori, M.C., and Woopen, C. (2024). Long-term effects of a telemedically-assisted lifestyle intervention on glycemic control in patients with type 2 diabetes - A two-armed randomised controlled trial in Germany. J Diabetes Metab Disord23, 519-532. 10.1007/s40200-023-01290-6.
- Ferring, A., Muck, L., Stegemann, J., Wiebe, L., Becker, I., Benzing, T., Meyer, A.M., and Polidori, M.C. (2024). Prognostic Features of Sarcopenia in Older Hospitalized Patients: A 6-Month Follow-Up Study. J Clin Med13. 10.3390/jcm13113116.
- Ferrucci, L., Tanaka, T., and Polidori, M.C. (2024). Can geroscience be translated into healthcare? Z Gerontol Geriatr57, 349-354. 10.1007/s00391-024-02326-z.
- Hochleitner, M., Pickert, L., Nolting, N.A., Affeldt, A.M., Becker, I., Benzing, T., Kochanek, M., and Polidori, M.C. (2024). Patient- vs organ-based prognostic tools for older patients in critical care units : An observational study with a 3-month follow-up. Med Klin Intensivmed Notfmed10.1007/s00063-024-01179-z. 10.1007/s00063-024-01179-z.
- Kudelka, J., Ollenschlager, M., Dodel, R., Eskofier, B.M., Hobert, M.A., Jahn, K., Klucken, J., Labeit, B., Polidori, M.C., Prell, T., Warnecke, T., von Arnim, C.A.F., Maetzler, W., Jacobs, A.H., and for the, D.G.G.w.g.N. (2024). Which Comprehensive Geriatric Assessment (CGA) instruments are currently used in Germany: a survey. BMC Geriatr24, 347. 10.1186/s12877-024-04913-6.
- Kunkler, M.C., Falkenreck, J.M., Ophey, A., Dencker, K., Friese, A., Jahr, P., Kalbe, E., Nelles, G., and Polidori, M.C. (2024). Long-Term Effects of the Multicomponent Program BrainProtect((R)) on Cognitive Function: One-Year Follow-Up in Healthy Adults. J Alzheimers Dis Rep8, 1069-1087. 10.3233/ADR-230199.
- Morganti, W., Custodero, C., Veronese, N., Topinkova, E., Michalkova, H., Polidori, M.C., Cruz-Jentoft, A.J., von Arnim, C.A.F., Azzini, M., Gruner, H., Castagna, A., Cenderello, G., Custureri, R., Seminerio, E., Zieschang, T., Padovani, A., Sanchez-Garcia, E., Pilotto, A., and Investigators, M.-C.-S.G. (2024). The Multidimensional Prognostic Index predicts incident delirium among hospitalized older patients with COVID-19: a multicenter prospective European study. Eur Geriatr Med15, 961-969. 10.1007/s41999-024-00987-y.
- Pickert, L., Dias, I.H.K., Thimm, A., Weber, J., Abdullah, S., Deelen, J., and Polidori, M.C. (2024). Micronutrients, Frailty, and Cognitive Impairment: Design and Preliminary Results from the CogLife 2.0 Study. J Alzheimers Dis100, S251-S263. 10.3233/JAD-240654.
- Polidori, M.C. (2024). Geroscience in the continuum from healthy longevity to frailty. Z Gerontol Geriatr57, 361-364. 10.1007/s00391-024-02331-2.
- Polidori, M.C. (2024). Embracing complexity of (brain) aging. FEBS Lett598, 2067-2073. 10.1002/1873-3468.14941.
- Polidori, M.C. (2024). Aging hallmarks, biomarkers, and clocks for personalized medicine: (re)positioning the limelight. Free Radic Biol Med215, 48-55. 10.1016/j.freeradbiomed.2024.02.012.
- Sittig, J., Pickert, L., Weigert, H., Deelen, J., Polidori, M.C., and Nelles, G. (2024). Relationship Between Endothelial Function, Vital Parameters, and Cognitive Performance in Community Dwellers with Subjective Cognitive Decline: An Observational Study with Six Months Follow Up. J Alzheimers Dis100, S13-S24. 10.3233/JAD-240661.
- Stegemann, J., Affeldt, A.M., Muck, L., Ferring, A., Gerhards, L., Pickert, L., Bausch, A., Benzing, T., Antczak, P., and Polidori, M.C. (2024). Prognostic signature of multimorbidity, geriatric syndromes and resources cluster in older in- and outpatients: a pooled secondary analysis with a 6-month follow-up. BMJ Open14, e086975. 10.1136/bmjopen-2024-086975.
- Verleysdonk, J., Noetzel, N., Becker, I., Pickert, L., Benzing, T., Pfister, R., Polidori, M.C., and Affeldt, A.M. (2024). Profiles of Geriatric Syndromes and Resources in Older Patients with Atrial Fibrillation. J Clin Med13. 10.3390/jcm13144009.
- Dunkel, A., von Storch, K., Hochheim, M., Zank, S., Polidori, M.C., and Woopen, C. (2025). Long-Term Effects of Transtheoretical Model-Based Lifestyle Intervention on Self-efficacy and Self-management in Patients with Type 2 Diabetes - Randomised Controlled Trial. Int J Behav Med32, 45-57. 10.1007/s12529-024-10323-0.
- Gutzeit, J., Weiss, M., Nurnberger, C., Lemhofer, C., Appel, K.S., Pracht, E., Reese, J.P., Lehmann, C., Polidori, M.C., Hein, G., and Deckert, J. (2025). Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review. Eur Arch Psychiatry Clin Neurosci275, 129-140. 10.1007/s00406-024-01868-y.
Simon Pöpsel
- Sauer, P.V., Pavlenko, E., Cookis, T., Zirden, L.C., Renn, J., Singhal, A., Hunold, P., Hoehne-Wiechmann, M.N., van Ray, O., Kaschani, F., Kaiser, M., Hansel-Hertsch, R., Sanbonmatsu, K.Y., Nogales, E., and Poepsel, S. (2024). Activation of automethylated PRC2 by dimerization on chromatin. Mol Cell84, 3885-3898 e3888. 10.1016/j.molcel.2024.08.025.
- Zheng, R., Moynahan, K., Georgomanolis, T., Pavlenko, E., Geissen, S., Mizi, A., Grimm, S., Nemade, H., Rehimi, R., Bastigkeit, J., Lackmann, J.W., Adam, M., Rada-Iglesias, A., Nuernberg, P., Klinke, A., Poepsel, S., Baldus, S., Papantonis, A., and Kargapolova, Y. (2024). Remodeling of the endothelial cell transcriptional program via paracrine and DNA-binding activities of MPO. iScience27, 108898. 10.1016/j.isci.2024.108898.
Alfredo Ramirez
- Ahmad, S., Yang, W., Orellana, A., Frolich, L., de Rojas, I., Cano, A., Boada, M., Hernandez, I., Hausner, L., Harms, A.C., Bakker, M.H.M., Cabrera-Socorro, A., Amin, N., Ramirez, A., Ruiz, A., Van Duijn, C.M., and Hankemeier, T. (2024). Association of oxidative stress and inflammatory metabolites with Alzheimer's disease cerebrospinal fluid biomarkers in mild cognitive impairment. Alzheimers Res Ther16, 171. 10.1186/s13195-024-01542-4.
- Baumeister, H., Vogel, J.W., Insel, P.S., Kleineidam, L., Wolfsgruber, S., Stark, M., Gellersen, H.M., Yakupov, R., Schmid, M.C., Lusebrink, F., Brosseron, F., Ziegler, G., Freiesleben, S.D., Preis, L., Schneider, L.S., Spruth, E.J., Altenstein, S., Lohse, A., Fliessbach, K., Vogt, I.R., Bartels, C., Schott, B.H., Rostamzadeh, A., Glanz, W., Incesoy, E.I., Butryn, M., Janowitz, D., Rauchmann, B.S., Kilimann, I., Goerss, D., Munk, M.H., Hetzer, S., Dechent, P., Ewers, M., Scheffler, K., Wuestefeld, A., Strandberg, O., van Westen, D., Mattsson-Carlgren, N., Janelidze, S., Stomrud, E., Palmqvist, S., Spottke, A., Laske, C., Teipel, S., Perneczky, R., Buerger, K., Schneider, A., Priller, J., Peters, O., Ramirez, A., Wiltfang, J., Heneka, M.T., Wagner, M., Duzel, E., Jessen, F., Hansson, O., and Berron, D. (2024). A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings. Brain147, 2400-2413. 10.1093/brain/awae118.
- Beer, S., Elmenhorst, D., Bischof, G.N., Ramirez, A., Bauer, A., Drzezga, A., and Alzheimer's Disease Neuroimaging, I. (2024). Explainable artificial intelligence identifies an AQP4 polymorphism-based risk score associated with brain amyloid burden. Neurobiol Aging143, 19-29. 10.1016/j.neurobiolaging.2024.08.002.
- Chatterjee, M., Ozdemir, S., Fritz, C., Mobius, W., Kleineidam, L., Mandelkow, E., Biernat, J., Dogdu, C., Peters, O., Cosma, N.C., Wang, X., Schneider, L.S., Priller, J., Spruth, E., Kuhn, A.A., Krause, P., Klockgether, T., Vogt, I.R., Kimmich, O., Spottke, A., Hoffmann, D.C., Fliessbach, K., Miklitz, C., McCormick, C., Weydt, P., Falkenburger, B., Brandt, M., Guenther, R., Dinter, E., Wiltfang, J., Hansen, N., Bahr, M., Zerr, I., Floel, A., Nestor, P.J., Duzel, E., Glanz, W., Incesoy, E., Burger, K., Janowitz, D., Perneczky, R., Rauchmann, B.S., Hopfner, F., Wagemann, O., Levin, J., Teipel, S., Kilimann, I., Goerss, D., Prudlo, J., Gasser, T., Brockmann, K., Mengel, D., Zimmermann, M., Synofzik, M., Wilke, C., Selma-Gonzalez, J., Turon-Sans, J., Santos-Santos, M.A., Alcolea, D., Rubio-Guerra, S., Fortea, J., Carbayo, A., Lleo, A., Rojas-Garcia, R., Illan-Gala, I., Wagner, M., Frommann, I., Roeske, S., Bertram, L., Heneka, M.T., Brosseron, F., Ramirez, A., Schmid, M., Beschorner, R., Halle, A., Herms, J., Neumann, M., Barthelemy, N.R., Bateman, R.J., Rizzu, P., Heutink, P., Dols-Icardo, O., Hoglinger, G., Hermann, A., and Schneider, A. (2024). Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS. Nat Med30, 1771-1783. 10.1038/s41591-024-02937-4.
- Deike, K., Decker, A., Scheyhing, P., Harten, J., Zimmermann, N., Paech, D., Peters, O., Freiesleben, S.D., Schneider, L.S., Preis, L., Priller, J., Spruth, E., Altenstein, S., Lohse, A., Fliessbach, K., Kimmich, O., Wiltfang, J., Bartels, C., Hansen, N., Jessen, F., Rostamzadeh, A., Duzel, E., Glanz, W., Incesoy, E.I., Butryn, M., Buerger, K., Janowitz, D., Ewers, M., Perneczky, R., Rauchmann, B.S., Teipel, S., Kilimann, I., Goerss, D., Laske, C., Munk, M.H., Spottke, A., Roy, N., Wagner, M., Roeske, S., Heneka, M.T., Brosseron, F., Ramirez, A., Dobisch, L., Wolfsgruber, S., Kleineidam, L., Yakupov, R., Stark, M., Schmid, M.C., Berger, M., Hetzer, S., Dechent, P., Scheffler, K., Petzold, G.C., Schneider, A., Effland, A., and Radbruch, A. (2024). Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease. Invest Radiol59, 667-676. 10.1097/RLI.0000000000001077.
- Hayek, D., Ziegler, G., Kleineidam, L., Brosseron, F., Nemali, A., Vockert, N., Ravichandran, K.A., Betts, M.J., Peters, O., Schneider, L.S., Wang, X., Priller, J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Bartels, C., Rostamzadeh, A., Glanz, W., Buerger, K., Janowitz, D., Perneczky, R., Rauchmann, B.S., Teipel, S., Kilimann, I., Laske, C., Mengel, D., Synofzik, M., Munk, M.H., Spottke, A., Roy, N., Roeske, S., Kuhn, E., Ramirez, A., Dobisch, L., Schmid, M., Berger, M., Wolfsgruber, S., Yakupov, R., Hetzer, S., Dechent, P., Ewers, M., Scheffler, K., Schott, B.H., Schreiber, S., Orellana, A., de Rojas, I., Marquie, M., Boada, M., Sotolongo, O., Gonzalez, P.G., Puerta, R., Duzel, E., Jessen, F., Wagner, M., Ruiz, A., Heneka, M.T., and Maass, A. (2024). Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition. Mol Psychiatry29, 992-1004. 10.1038/s41380-023-02387-3.
- Heneka, M.T., van der Flier, W.M., Jessen, F., Hoozemanns, J., Thal, D.R., Boche, D., Brosseron, F., Teunissen, C., Zetterberg, H., Jacobs, A.H., Edison, P., Ramirez, A., Cruchaga, C., Lambert, J.C., Laza, A.R., Sanchez-Mut, J.V., Fischer, A., Castro-Gomez, S., Stein, T.D., Kleineidam, L., Wagner, M., Neher, J.J., Cunningham, C., Singhrao, S.K., Prinz, M., Glass, C.K., Schlachetzki, J.C.M., Butovsky, O., Kleemann, K., De Jaeger, P.L., Scheiblich, H., Brown, G.C., Landreth, G., Moutinho, M., Grutzendler, J., Gomez-Nicola, D., McManus, R.M., Andreasson, K., Ising, C., Karabag, D., Baker, D.J., Liddelow, S.A., Verkhratsky, A., Tansey, M., Monsonego, A., Aigner, L., Dorothee, G., Nave, K.A., Simons, M., Constantin, G., Rosenzweig, N., Pascual, A., Petzold, G.C., Kipnis, J., Venegas, C., Colonna, M., Walter, J., Tenner, A.J., O'Banion, M.K., Steinert, J.R., Feinstein, D.L., Sastre, M., Bhaskar, K., Hong, S., Schafer, D.P., Golde, T., Ransohoff, R.M., Morgan, D., Breitner, J., Mancuso, R., and Riechers, S.P. (2024). Neuroinflammation in Alzheimer disease. Nat Rev Immunol10.1038/s41577-024-01104-7. 10.1038/s41577-024-01104-7.
- Le Borgne, J., Gomez, L., Heikkinen, S., Amin, N., Ahmad, S., Choi, S.H., Bis, J., Grenier-Boley, B., Rodriguez, O.G., Kleineidam, L., Young, J., Tripathi, K.P., Wang, L., Varma, A., Campos-Martin, R., van der Lee, S., Damotte, V., de Rojas, I., Palmal, S., Eadb, G.R.A.C.E.D.E.G.D.F.A.C., Lipton, R., Reiman, E., McKee, A., De Jager, P., Bush, W., Small, S., Levey, A., Saykin, A., Foroud, T., Albert, M., Hyman, B., Petersen, R., Younkin, S., Sano, M., Wisniewski, T., Vassar, R., Schneider, J., Henderson, V., Roberson, E., DeCarli, C., LaFerla, F., Brewer, J., Swerdlow, R., Van Eldik, L., Hamilton-Nelson, K., Paulson, H., Naj, A., Lopez, O., Chui, H., Crane, P., Grabowski, T., Kukull, W., Asthana, S., Craft, S., Strittmatter, S., Cruchaga, C., Leverenz, J., Goate, A., Kamboh, M.I., George-Hyslop, P.S., Valladares, O., Kuzma, A., Cantwell, L., Riemenschneider, M., Morris, J., Slifer, S., Dalmasso, C., Castillo, A., Kucukali, F., Peters, O., Schneider, A., Dichgans, M., Rujescu, D., Scherbaum, N., Deckert, J., Riedel-Heller, S., Hausner, L., Molina-Porcel, L., Duzel, E., Grimmer, T., Wiltfang, J., Heilmann-Heimbach, S., Moebus, S., Tegos, T., Scarmeas, N., Dols-Icardo, O., Moreno, F., Perez-Tur, J., Bullido, M.J., Pastor, P., Sanchez-Valle, R., Alvarez, V., Boada, M., Garcia-Gonzalez, P., Puerta, R., Mir, P., Real, L.M., Pinol-Ripoll, G., Garcia-Alberca, J.M., Royo, J.L., Rodriguez-Rodriguez, E., Soininen, H., de Mendonca, A., Mehrabian, S., Traykov, L., Hort, J., Vyhnalek, M., Thomassen, J.Q., Pijnenburg, Y.A.L., Holstege, H., van Swieten, J., Ramakers, I., Verhey, F., Scheltens, P., Graff, C., Papenberg, G., Giedraitis, V., Boland, A., Deleuze, J.F., Nicolas, G., Dufouil, C., Pasquier, F., Hanon, O., Debette, S., Grunblatt, E., Popp, J., Ghidoni, R., Galimberti, D., Arosio, B., Mecocci, P., Solfrizzi, V., Parnetti, L., Squassina, A., Tremolizzo, L., Borroni, B., Nacmias, B., Spallazzi, M., Seripa, D., Rainero, I., Daniele, A., Bossu, P., Masullo, C., Rossi, G., Jessen, F., Fernandez, V., Kehoe, P.G., Frikke-Schmidt, R., Tsolaki, M., Sanchez-Juan, P., Sleegers, K., Ingelsson, M., Haines, J., Farrer, L., Mayeux, R., Wang, L.S., Sims, R., DeStefano, A., Schellenberg, G.D., Seshadri, S., Amouyel, P., Williams, J., van der Flier, W., Ramirez, A., Pericak-Vance, M., Andreassen, O.A., Van Duijn, C., Hiltunen, M., Ruiz, A., Dupuis, J., Martin, E., Lambert, J.C., Kunkle, B., and Bellenguez, C. (2024). X-chromosome-wide association study for Alzheimer's disease. Mol Psychiatry10.1038/s41380-024-02838-5. 10.1038/s41380-024-02838-5.
- Martino-Adami, P.V., Chatterjee, M., Kleineidam, L., Weyerer, S., Bickel, H., Wiese, B., Riedel-Heller, S.G., Scherer, M., Blennow, K., Zetterberg, H., Wagner, M., Schneider, A., and Ramirez, A. (2024). Prognostic value of Alzheimer's disease plasma biomarkers in the oldest-old: a prospective primary care-based study. Lancet Reg Health Eur45, 101030. 10.1016/j.lanepe.2024.101030.
- Pan, X., Chandrasekaran, S., Woodside, J.V., Riedel-Heller, S.G., Scherer, M., Wagner, M., Ramirez, A., and Green, B.D. (2024). Development, validation and application of an LC-MS/MS method quantifying free forms of the micronutrients queuine and queuosine in human plasma using a surrogate matrix approach. Anal Bioanal Chem416, 5711-5719. 10.1007/s00216-024-05489-1.
- Preis, L., Villringer, K., Brosseron, F., Duzel, E., Jessen, F., Petzold, G.C., Ramirez, A., Spottke, A., Fiebach, J.B., and Peters, O. (2024). Assessing blood-brain barrier dysfunction and its association with Alzheimer's pathology, cognitive impairment and neuroinflammation. Alzheimers Res Ther16, 172. 10.1186/s13195-024-01529-1.
- Ruiz-Rizzo, A.L., Finke, K., Damoiseaux, J.S., Bartels, C., Buerger, K., Cosma, N.C., Dechent, P., Dobisch, L., Ewers, M., Fliessbach, K., Frommann, I., Glanz, W., Goerss, D., Hetzer, S., Incesoy, E.I., Janowitz, D., Kilimann, I., Laske, C., van Lent, D.M., Munk, M.H.J., Peters, O., Priller, J., Ramirez, A., Rostamzadeh, A., Roy, N., Scheffler, K., Schneider, A., Spottke, A., Spruth, E.J., Teipel, S., Wagner, M., Wiltfang, J., Yakupov, R., Jessen, F., Duezel, E., Perneczky, R., and Rauchmann, B.S. (2024). Fornix fractional anisotropy mediates the association between Mediterranean diet adherence and memory four years later in older adults without dementia. Neurobiol Aging136, 99-110. 10.1016/j.neurobiolaging.2024.01.012.
- Saadmaan, G., Dalmasso, M.C., Ramirez, A., Hiltunen, M., Kemppainen, N., Lehtisalo, J., Mangialasche, F., Ngandu, T., Rinne, J., Soininen, H., Stephen, R., Kivipelto, M., and Solomon, A. (2024). Alzheimer's disease genetic risk score and neuroimaging in the FINGER lifestyle trial. Alzheimers Dement20, 4345-4350. 10.1002/alz.13843.
- Sampatakakis, S.N., Mourtzi, N., Charisis, S., Kalligerou, F., Mamalaki, E., Ntanasi, E., Hatzimanolis, A., Koutsis, G., Ramirez, A., Lambert, J.C., Yannakoulia, M., Kosmidis, M.H., Dardiotis, E., Hadjigeorgiou, G., Sakka, P., Rouskas, K., Patas, K., and Scarmeas, N. (2024). Cerebral Amyloidosis in Individuals with Subjective Cognitive Decline: From Genetic Predisposition to Actual Cerebrospinal Fluid Measurements. Biomedicines12. 10.3390/biomedicines12051053.
- Sampatakakis, S.N., Mourtzi, N., Charisis, S., Mamalaki, E., Ntanasi, E., Hatzimanolis, A., Ramirez, A., Lambert, J.C., Yannakoulia, M., Kosmidis, M.H., Dardiotis, E., Hadjigeorgiou, G., Sakka, P., and Scarmeas, N. (2024). Genetic Predisposition for White Matter Hyperintensities and Risk of Mild Cognitive Impairment and Alzheimer's Disease: Results from the HELIAD Study. Curr Issues Mol Biol46, 934-947. 10.3390/cimb46010060.
- Shao, K., Hu, X., Kleineidam, L., Stark, M., Altenstein, S., Amthauer, H., Boecker, H., Buchert, R., Buerger, K., Butryn, M., Cai, Y., Cai, Y., Cosma, N.C., Chen, G., Chen, Z., Daamen, M., Drzezga, A., Duzel, E., Essler, M., Ewers, M., Fliessbach, K., Gaertner, F.C., Glanz, W., Guo, T., Hansen, N., He, B., Janowitz, D., Kilimann, I., Krause, B.J., Lan, G., Lange, C., Laske, C., Li, Y., Li, R., Liu, L., Lu, J., Meng, F., Munk, M.H., Peters, O., Perneczky, R., Priller, J., Ramirez, A., Rauchmann, B.S., Reimold, M., Rominger, A., Rostamzadeh, A., Roy-Kluth, N., Schneider, A., Spottke, A., Spruth, E.J., Sun, P., Teipel, S., Wang, X., Wei, M., Wei, Y., Wiltfang, J., Yan, S., Yang, J., Yu, X., Zhang, M., Zhang, L., Delcode study group, S.s.g., Wagner, M., Jessen, F., Han, Y., and Kuhn, E. (2024). Amyloid and SCD jointly predict cognitive decline across Chinese and German cohorts. Alzheimers Dement20, 5926-5939. 10.1002/alz.14119.
- Soch, J., Richter, A., Kizilirmak, J.M., Schutze, H., Ziegler, G., Altenstein, S., Brosseron, F., Dechent, P., Fliessbach, K., Freiesleben, S.D., Glanz, W., Gref, D., Heneka, M.T., Hetzer, S., Incesoy, E.I., Kilimann, I., Kimmich, O., Kleineidam, L., Kuhn, E., Laske, C., Lohse, A., Lusebrink, F., Munk, M.H., Peters, O., Preis, L., Priller, J., Ramirez, A., Roeske, S., Rostamzadeh, A., Roy-Kluth, N., Scheffler, K., Schmid, M., Schneider, A., Spottke, A., Spruth, E.J., Teipel, S., Wiltfang, J., Jessen, F., Wagner, M., Duzel, E., and Schott, B.H. (2024). Single-value brain activity scores reflect both severity and risk across the Alzheimer's continuum. Brain147, 3789-3803. 10.1093/brain/awae149.
- Strom, N.I., Gerring, Z.F., Galimberti, M., Yu, D., Halvorsen, M.W., Abdellaoui, A., Rodriguez-Fontenla, C., Sealock, J.M., Bigdeli, T., Coleman, J.R., Mahjani, B., Thorp, J.G., Bey, K., Burton, C.L., Luykx, J.J., Zai, G., Alemany, S., Andre, C., Askland, K.D., Banaj, N., Barlassina, C., Nissen, J.B., Bienvenu, O.J., Black, D., Bloch, M.H., Boberg, J., Borte, S., Bosch, R., Breen, M., Brennan, B.P., Brentani, H., Buxbaum, J.D., Bybjerg-Grauholm, J., Byrne, E.M., Cabana-Dominguez, J., Camarena, B., Camarena, A., Cappi, C., Carracedo, A., Casas, M., Cavallini, M.C., Ciullo, V., Cook, E.H., Crosby, J., Cullen, B.A., De Schipper, E.J., Delorme, R., Djurovic, S., Elias, J.A., Estivill, X., Falkenstein, M.J., Fundin, B.T., Garner, L., German, C., Gironda, C., Goes, F.S., Grados, M.A., Grove, J., Guo, W., Haavik, J., Hagen, K., Harrington, K., Havdahl, A., Hoffler, K.D., Hounie, A.G., Hucks, D., Hultman, C., Janecka, M., Jenike, E., Karlsson, E.K., Kelley, K., Klawohn, J., Krasnow, J.E., Krebs, K., Lange, C., Lanzagorta, N., Levey, D., Lindblad-Toh, K., Macciardi, F., Maher, B., Mathes, B., McArthur, E., McGregor, N., McLaughlin, N.C., Meier, S., Miguel, E.C., Mulhern, M., Nestadt, P.S., Nurmi, E.L., O'Connell, K.S., Osiecki, L., Ousdal, O.T., Palviainen, T., Pedersen, N.L., Piras, F., Piras, F., Potluri, S., Rabionet, R., Ramirez, A., Rauch, S., Reichenberg, A., Riddle, M.A., Ripke, S., Rosario, M.C., Sampaio, A.S., Schiele, M.A., Skogholt, A.H., Sloofman, L., Smit, J., Soler, A.M., Thomas, L.F., Tifft, E., Vallada, H., van Kirk, N., Veenstra-VanderWeele, J., Vulink, N.N., Walker, C.P., Wang, Y., Wendland, J.R., Winsvold, B.S., Yao, Y., Zhou, H., andMe Research, T., Va Million Veteran Program, E.B., CoGa research, t., iPsych, H.r.t., team, N.O.r., Agrawal, A., Alonso, P., Berberich, G., Bucholz, K.K., Bulik, C.M., Cath, D., Denys, D., Eapen, V., Edenberg, H., Falkai, P., Fernandez, T.V., Fyer, A.J., Gaziano, J.M., Geller, D.A., Grabe, H.J., Greenberg, B.D., Hanna, G.L., Hickie, I.B., Hougaard, D.M., Kathmann, N., Kennedy, J., Lai, D., Landen, M., Le Hellard, S., Leboyer, M., Lochner, C., McCracken, J.T., Medland, S.E., Mortensen, P.B., Neale, B.M., Nicolini, H., Nordentoft, M., Pato, M., Pato, C., Pauls, D.L., Piacentini, J., Pittenger, C., Posthuma, D., Ramos-Quiroga, J.A., Rasmussen, S.A., Richter, M.A., Rosenberg, D.R., Ruhrmann, S., Samuels, J.F., Sandin, S., Sandor, P., Spalletta, G., Stein, D.J., Stewart, S.E., Storch, E.A., Stranger, B.E., Turiel, M., Werge, T., Andreassen, O.A., Borglum, A.D., Walitza, S., Hveem, K., Hansen, B.K., Ruck, C.P., Martin, N.G., Milani, L., Mors, O., Reichborn-Kjennerud, T., Ribases, M., Kvale, G., Mataix-Cols, D., Domschke, K., Grunblatt, E., Wagner, M., Zwart, J.A., Breen, G., Nestadt, G., Kaprio, J., Arnold, P.D., Grice, D.E., Knowles, J.A., Ask, H., Verweij, K.J., Davis, L.K., Smit, D.J., Crowley, J.J., Scharf, J.M., Stein, M.B., Gelernter, J., Mathews, C.A., Derks, E.M., and Mattheisen, M. (2024). Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci. medRxiv10.1101/2024.03.13.24304161. 10.1101/2024.03.13.24304161.
- Teipel, S.J., Dyrba, M., Kleineidam, L., Brosseron, F., Levin, F., Bruno, D., Buerger, K., Cosma, N., Schneider, L.S., Düzel, E., Glanz, W., Fliessbach, K., Janowitz, D., Kilimann, I., Laske, C., Munk, M.H., Maier, F., Peters, O., Pomara, N., Perneczky, R., Rauchmann, B.S., Priller, J., Ramirez, A., Roy, N., Schneider, A., Spottke, A., Spruth, E.J., Roeske, S., Wagner, M., Wiltfang, J., Wolfsgruber, S., Bartels, C., Jessen, F., Heneka, M.T., and Alzheimert, D.S.G. (2024). Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline. Alzh Dement-Dadm16. 10.1002/dad2.12510.
- Wang, X., Freiesleben, S.D., Schneider, L.S., Preis, L., Priller, J., Spruth, E.J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Hansen, N., Jessen, F., Rostamzadeh, A., Duzel, E., Glanz, W., Incesoy, E.I., Buerger, K., Janowitz, D., Ewers, M., Perneczky, R., Rauchmann, B.S., Teipel, S.J., Kilimann, I., Goerss, D., Laske, C., Munk, M.H.J., Spottke, A., Roy-Kluth, N., Heneka, M.T., Brosseron, F., Wagner, M., Wolfsgruber, S., Ramirez, A., Kleineidam, L., Stark, M., and Peters, O. (2024). Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline. Neurology103, e209806. 10.1212/WNL.0000000000209806.
- Sampatakakis, S.N., Mourtzi, N., Charisis, S., Mamalaki, E., Ntanasi, E., Hatzimanolis, A., Ramirez, A., Lambert, J.C., Yannakoulia, M., Kosmidis, M.H., Dardiotis, E., Hadjigeorgiou, G., Megalou, M., Sakka, P., and Scarmeas, N. (2025). Walking time and genetic predisposition for Alzheimer's disease: Results from the HELIAD study. Clin Neuropsychol39, 83-99. 10.1080/13854046.2024.2344869.
Jan Riemer
- Racho, J., and Riemer, J. (2024). Approaches for the analysis of redox-dependent protein import into mitochondria of mammalian cells. Methods Enzymol707, 637-671. 10.1016/bs.mie.2024.07.031.
- Rothemann, R.A., Stobbe, D., Hoehne-Wiechmann, M.N., Murschall, L.M., Peker, E., Knaup, L.K., Racho, J., Habich, M., Gerlich, S., Lapacz, K.J., Ulrich, K., and Riemer, J. (2024). Interaction with the cysteine-free protein HAX1 expands the substrate specificity and function of MIA40 beyond protein oxidation. FEBS J291, 5506-5522. 10.1111/febs.17328.
- Scherschel, M., Niemeier, J.O., Jacobs, L., Hoffmann, M.D.A., Diederich, A., Bell, C., Hohne, P., Raetz, S., Kroll, J.B., Steinbeck, J., Lichtenauer, S., Multhoff, J., Zimmermann, J., Sadhanasatish, T., Rothemann, R.A., Grashoff, C., Messens, J., Ampofo, E., Laschke, M.W., Riemer, J., Roma, L.P., Schwarzlander, M., and Morgan, B. (2024). A family of NADPH/NADP(+) biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes. Nat Commun15, 10704. 10.1038/s41467-024-55302-x.
- Zarges, C., and Riemer, J. (2024). Oxidative protein folding in the intermembrane space of human mitochondria. Febs Open Bio14, 1610-1626. 10.1002/2211-5463.13839.
- Shumanska, M., Lodygin, D., Gibhardt, C.S., Ickes, C., Stejerean-Todoran, I., Krause, L.C.M., Pahl, K., Jacobs, L., Paluschkiwitz, A., Liu, S., Boshnakovska, A., Voigt, N., Legler, T.J., Haubrock, M., Mitkovski, M., Poschmann, G., Rehling, P., Dennerlein, S., Riemer, J., Flugel, A., and Bogeski, I. (2025). Mitochondrial calcium uniporter complex controls T-cell-mediated immune responses. EMBO Rep26, 407-442. 10.1038/s44319-024-00313-4.
- Zimmermann, J., Lang, L., Calabrese, G., Laporte, H., Amponsah, P.S., Michalk, C., Sukmann, T., Oestreicher, J., Tursch, A., Peker, E., Owusu, T.N.E., Weith, M., Roma, L.P., Deponte, M., Riemer, J., and Morgan, B. (2025). Tsa1 is the dominant peroxide scavenger and a source of H(2)O(2)-dependent GSSG production in yeast. Free Radic Biol Med226, 408-420. 10.1016/j.freeradbiomed.2024.11.004.
Elena Rugarli
- Engelhardt, P.M., Veronese, M., Eryigit, A.A., Das, A., Kaczmarek, A.T., Rugarli, E.I., and Schmalz, H.G. (2024). A pH-Sensitive Double Chromophore Fluorescent Dye for Live-Tracking of Lipophagy. Chem-Eur J10.1002/chem.202400808. 10.1002/chem.202400808.
- Engelhardt, P.M., Veronese, M., Eryigit, A.A., Das, A., Kaczmarek, A.T., Rugarli, E.I., and Schmalz, H.G. (2024). A pH-Sensitive Double Chromophore Fluorescent Dye for Live-Tracking of Lipophagy. Chemistry30, e202400808. 10.1002/chem.202400808.
- Iavarone, F., Zaninello, M., Perrone, M., Monaco, M., Barth, E., Gaedke, F., Pizzo, M.T., Di Lorenzo, G., Desiderio, V., Sommella, E., Merciai, F., Salviati, E., Campiglia, P., Luongo, L., De Leonibus, E., Rugarli, E., and Settembre, C. (2024). Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo. EMBO Rep25, 3651-3677. 10.1038/s44319-024-00213-7.
- Veronese, M., Kallabis, S., Kaczmarek, A.T., Das, A., Robers, L., Schumacher, S., Lofrano, A., Brodesser, S., Muller, S., Hofmann, K., Kruger, M., and Rugarli, E.I. (2024). ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway. Life Sci Alliance7. 10.26508/lsa.202402620.
- Zaninello, M., Schlegel, T., Nolte, H., Pirzada, M., Savino, E., Barth, E., Klein, I., Wustenberg, H., Uddin, T., Wolff, L., Wirth, B., Lehmann, H.C., Cioni, J.M., Langer, T., and Rugarli, E.I. (2024). CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy. Sci Adv10, eadn2050. 10.1126/sciadv.adn2050.
Anne Schäfer
- Faust, T.E., Lee, Y.H., O'Connor, C.D., Boyle, M.A., Gunner, G., Badimon, A., Ayata, P., Schaefer, A., and Schafer, D.P. (2024). Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling. bioRxiv10.1101/2024.02.08.579178. 10.1101/2024.02.08.579178.
- Scoyni, F., Sitnikova, V., Giudice, L., Korhonen, P., Trevisan, D.M., Hernandez de Sande, A., Gomez-Budia, M., Giniatullina, R., Ugidos, I.F., Dhungana, H., Pistono, C., Korvenlaita, N., Valimaki, N.N., Kangas, S.M., Hiltunen, A.E., Gribchenko, E., Kaikkonen-Maatta, M.U., Koistinaho, J., Yla-Herttuala, S., Hinttala, R., Veno, M.T., Su, J., Stoffel, M., Schaefer, A., Rajewsky, N., Kjems, J., LaPierre, M.P., Piwecka, M., Jolkkonen, J., Giniatullin, R., Hansen, T.B., and Malm, T. (2024). ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling. Cell Rep43, 113862. 10.1016/j.celrep.2024.113862.
To top
Bernhard Schermer
- Schömig, T., Diefenhardt, P., Plagmann, I., Trinsch, B., Merz, T., Crispatzu, G., Unnersjö-Jess, D., Nies, J., Pütz, D., Gonzalez, C.S., Schermer, B., Benzing, T., Brinkkoetter, P.T., and Brähler, S. (2024). The podocytes' inflammatory responses in experimental GN are independent of canonical MYD88-dependent toll-like receptor signaling. Sci Rep-Uk 14. 10.1038/s41598-024-52565-8.
To top
Björn Schumacher
- Arvanitaki, E.S., Goulielmaki, E., Gkirtzimanaki, K., Niotis, G., Tsakani, E., Nenedaki, E., Rouska, I., Kefalogianni, M., Xydias, D., Kalafatakis, I., Psilodimitrakopoulos, S., Karagogeos, D., Schumacher, B., Stratakis, E., and Garinis, G.A. (2024). Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage. Proc Natl Acad Sci U S A121, e2317402121. 10.1073/pnas.2317402121.
- Lyu, Y.X., Fu, Q., Wilczok, D., Ying, K., King, A., Antebi, A., Vojta, A., Stolzing, A., Moskalev, A., Georgievskaya, A., Maier, A.B., Olsen, A., Groth, A., Simon, A.K., Brunet, A., Jamil, A., Kulaga, A., Bhatti, A., Yaden, B., Pedersen, B.K., Schumacher, B., Djordjevic, B., Kennedy, B., Chen, C., Huang, C.Y., Correll, C.U., Murphy, C.T., Ewald, C.Y., Chen, D., Valenzano, D.R., Soldacki, D., Erritzoe, D., Meyer, D., Sinclair, D.A., Chini, E.N., Teeling, E.C., Morgen, E., Verdin, E., Vernet, E., Pinilla, E., Fang, E.F., Bischof, E., Mercken, E.M., Finger, F., Kuipers, F., Pun, F.W., Gyulveszi, G., Civiletto, G., Zmudze, G., Blander, G., Pincus, H.A., McClure, J., Kirkland, J.L., Peyer, J., Justice, J.N., Vijg, J., Gruhn, J.R., McLaughlin, J., Mannick, J., Passos, J., Baur, J.A., Betts-LaCroix, J., Sedivy, J.M., Speakman, J.R., Shlain, J., von Maltzahn, J., Andreasson, K.I., Moody, K., Palikaras, K., Fortney, K., Niedernhofer, L.J., Rasmussen, L.J., Veenhoff, L.M., Melton, L., Ferrucci, L., Quarta, M., Koval, M., Marinova, M., Hamalainen, M., Unfried, M., Ringel, M.S., Filipovic, M., Topors, M., Mitin, N., Roy, N., Pintar, N., Barzilai, N., Binetti, P., Singh, P., Kohlhaas, P., Robbins, P.D., Rubin, P., Fedichev, P.O., Kamya, P., Munoz-Canoves, P., de Cabo, R., Faragher, R.G.A., Konrad, R., Ripa, R., Mansukhani, R., Buttner, S., Wickstrom, S.A., Brunemeier, S., Jakimov, S., Luo, S., Rosenzweig-Lipson, S., Tsai, S.Y., Dimmeler, S., Rando, T.A., Peterson, T.R., Woods, T., Wyss-Coray, T., Finkel, T., Strauss, T., Gladyshev, V.N., Longo, V.D., Dwaraka, V.B., Gorbunova, V., Acosta-Rodriguez, V.A., Sorrentino, V., Sebastiano, V., Li, W., Suh, Y., Zhavoronkov, A., Scheibye-Knudsen, M., and Bakula, D. (2024). Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity. Aging (Albany NY)16, 12955-12976. 10.18632/aging.206135.
- Meyer, D.H., and Schumacher, B. (2024). Aging clocks based on accumulating stochastic variation. Nat Aging4, 871-885. 10.1038/s43587-024-00619-x.
- Moliere, A., Park, J.Y.C., Goyala, A., Vayndorf, E.M., Zhang, B., Hsiung, K.C., Jung, Y., Kwon, S., Statzer, C., Meyer, D., Nguyen, R., Chadwick, J., Thompson, M.A., Schumacher, B., Lee, S.V., Essmann, C.L., MacArthur, M.R., Kaeberlein, M., David, D., Gems, D., and Ewald, C.Y. (2024). Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age. Geroscience46, 5015-5036. 10.1007/s11357-024-01232-x.
- Panier, S., Wang, S., and Schumacher, B. (2024). Genome Instability and DNA Repair in Somatic and Reproductive Aging. Annu Rev Pathol19, 261-290. 10.1146/annurev-pathmechdis-051122-093128.
- Rieckher, M., Gallrein, C., Alquezar-Artieda, N., Bourached-Silva, N., Vaddavalli, P.L., Mares, D., Backhaus, M., Blindauer, T., Greger, K., Wiesner, E., Pontel, L.B., and Schumacher, B. (2024). Distinct DNA repair mechanisms prevent formaldehyde toxicity during development, reproduction and aging. Nucleic Acids Res52, 8271-8285. 10.1093/nar/gkae519.
- Ropert, B., Gallrein, C., and Schumacher, B. (2024). DNA repair deficiencies and neurodegeneration. DNA Repair (Amst)138, 103679. 10.1016/j.dnarep.2024.103679.
- Siametis, A., Stratigi, K., Giamaki, D., Chatzinikolaou, G., Akalestou-Clocher, A., Goulielmaki, E., Luke, B., Schumacher, B., and Garinis, G.A. (2024). Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence. Nat Commun15, 4061. 10.1038/s41467-024-48443-6.
Alessandra Stangherlin
- Rodriguez, S.G., Crosby, P., Hansen, L.L., Grunewald, E., Beale, A.D., Spangler, R.K., Rabbitts, B.M., Partch, C.L., Stangherlin, A., O'Neill, J.S., and van Ooijen, G. (2024). Potassium rhythms couple the circadian clock to the cell cycle. bioRxiv10.1101/2024.04.02.587153. 10.1101/2024.04.02.587153.
To top
Sophie Steculorum
- Decoster, L., Trova, S., Zucca, S., Bulk, J., Gouveia, A., Ternier, G., Lhomme, T., Legrand, A., Gallet, S., Boehm, U., Wyatt, A., Wahl, V., Wartenberg, P., Hrabovszky, E., Racz, G., Luzzati, F., Nato, G., Fogli, M., Peretto, P., Schriever, S.C., Bernecker, M., Pfluger, P.T., Steculorum, S.M., Bovetti, S., Rasika, S., Prevot, V., Silva, M.S.B., and Giacobini, P. (2024). A GnRH neuronal population in the olfactory bulb translates socially relevant odors into reproductive behavior in male mice. Nat Neurosci27, 1758-1773. 10.1038/s41593-024-01724-1.
- Pass, T., Ricke, K.M., Hofmann, P., Chowdhury, R.S., Nie, Y., Chinnery, P., Endepols, H., Neumaier, B., Carvalho, A., Rigoux, L., Steculorum, S.M., Prudent, J., Riemer, T., Aswendt, M., Liss, B., Brachvogel, B., and Wiesner, R.J. (2024). Preserved striatal innervation maintains motor function despite severe loss of nigral dopaminergic neurons. Brain147, 3189-3203. 10.1093/brain/awae089.
To top
Phillipp Steven
- Bhujbal, S., Rupenthal, I.D., Steven, P., and Agarwal, P. (2024). Inflammation in Dry Eye Disease-Pathogenesis, Preclinical Animal Models, and Treatments. J Ocul Pharmacol Ther40, 638-658. 10.1089/jop.2024.0103.
- Stern, M.E., Theofilopoulos, A.N., Steven, P., Niederkorn, J.Y., Fox, R., Calonge, M., Scheid, C., and Pflugfelder, S.C. (2024). Immunologic basis for development of keratoconjunctivitis sicca in systemic autoimmune diseases: Role of innate immune sensors. Ocul Surf32, 130-138. 10.1016/j.jtos.2024.02.003.
- Steven, P., Mays, J.W., and Hashmi, S.K. (2024). Ocular and Oral Complications. In The EBMT Handbook: Hematopoietic Cell Transplantation and Cellular Therapies, A. Sureda, S. Corbacioglu, R. Greco, N. Kroger, and E. Carreras, eds. pp. 435-440. 10.1007/978-3-031-44080-9_48.
- Tahmaz, V., Menghesha, L., Stern, M.E., Holtick, U., Scheid, C., and Steven, P. (2024). Insulin eye drops for severe refractory chronic ocular graft-versus-host disease. Bone Marrow Transplant59, 1031-1033. 10.1038/s41409-024-02272-9.
To top
Eline Slagboom
- Bizzarri, D., Reinders, M.J.T., Kuiper, L., Beekman, M., Deelen, J., van Meurs, J.B.J., van Dongen, J., Pool, R., Boomsma, D.I., Ghanbari, M., Franke, L., Consortium, B., Slagboom, P.E., and van den Akker, E.B. (2024). NMR metabolomics-guided DNA methylation mortality predictors. Ebiomedicine107, 105279. 10.1016/j.ebiom.2024.105279.
- Boone, I., Tuerlings, M., Coutinho de Almeida, R., Lehmann, J., Ramos, Y., Nelissen, R., Slagboom, E., de Keizer, P., and Meulenbelt, I. (2024). Identified senescence endotypes in aged cartilage are reflected in the blood metabolome. Geroscience46, 2359-2369. 10.1007/s11357-023-01001-2.
- Jia, X., Fan, J., Wu, X., Cao, X., Ma, L., Abdelrahman, Z., Zhao, F., Zhu, H., Bizzarri, D., Akker, E., Slagboom, P.E., Deelen, J., Zhou, D., and Liu, Z. (2024). A Novel Metabolomic Aging Clock Predicting Health Outcomes and Its Genetic and Modifiable Factors. Adv Sci (Weinh)11, e2406670. 10.1002/advs.202406670.
- Sluiskes, M., Goeman, J., Beekman, M., Slagboom, E., van den Akker, E., Putter, H., and Rodriguez-Girondo, M. (2024). The AccelerAge framework: a new statistical approach to predict biological age based on time-to-event data. Eur J Epidemiol39, 623-641. 10.1007/s10654-024-01114-8.
- Sluiskes, M.H., Goeman, J.J., Beekman, M., Slagboom, P.E., Putter, H., and Rodriguez-Girondo, M. (2024). Clarifying the biological and statistical assumptions of cross-sectional biological age predictors: an elaborate illustration using synthetic and real data. BMC Med Res Methodol24, 58. 10.1186/s12874-024-02181-x.
- Smit, A.P., Herber, G.M., Kuiper, L.M., Rietman, M.L., Wesenhagen, K.E.J., Picavet, H.S.J., Slagboom, P.E., and Verschuren, W.M.M. (2024). Association between metabolomics-based biomarker scores and 10-year cognitive decline in men and women. The Doetinchem Cohort Study. Age Ageing53. 10.1093/ageing/afae256.
- van Holstein, Y., Mooijaart, S.P., van Oevelen, M., van Deudekom, F.J., Vojinovic, D., Bizzarri, D., van den Akker, E.B., Noordam, R., Deelen, J., van Heemst, D., de Glas, N.A., Holterhues, C., Labots, G., van den Bos, F., Beekman, M., Slagboom, P.E., van Munster, B.C., Portielje, J.E.A., and Trompet, S. (2024). The performance of metabolomics-based prediction scores for mortality in older patients with solid tumors. Geroscience46, 5615-5627. 10.1007/s11357-024-01261-6.
Gilles Storelli
- Vonolfen, M.C., Meyer Zu Altenschildesche, F.L., Nam, H.J., Brodesser, S., Gyenis, A., Buellesbach, J., Lam, G., Thummel, C.S., and Storelli, G. (2024). Drosophila HNF4 acts in distinct tissues to direct a switch between lipid storage and export in the gut. Cell Rep43, 114693. 10.1016/j.celrep.2024.114693.
To top
Marc Tittgemeyer
- Asendorf, A.L., Theis, H., Tittgemeyer, M., Timmermann, L., Fink, G.R., Drzezga, A., Eggers, C., Ruppert-Junck, M.C., Pedrosa, D.J., Hoenig, M.C., and van Eimeren, T. (2024). Dynamic properties in functional connectivity changes and striatal dopamine deficiency in Parkinson's disease. Hum Brain Mapp45, e26776. 10.1002/hbm.26776.
- Banwinkler, M., Dzialas, V., Rigoux, L., Asendorf, A.L., Theis, H., Giehl, K., Tittgemeyer, M., Hoenig, M.C., and van Eimeren, T. (2024). Putaminal dopamine modulates movement motivation in Parkinson's disease. Brain147, 3352-3357. 10.1093/brain/awae214.
- Ruppert-Junck, M.C., Kraling, G., Greuel, A., Tittgemeyer, M., Timmermann, L., Drzezga, A., Eggers, C., and Pedrosa, D. (2024). Random forest analysis of midbrain hypometabolism using [(18)F]-FDG PET identifies Parkinson's disease at the subject-level. Front Comput Neurosci18, 1328699. 10.3389/fncom.2024.1328699.
- Tuscher, O., Muthuraman, M., Horstmann, J.P., Horta, G., Radyushkin, K., Baumgart, J., Sigurdsson, T., Endle, H., Ji, H., Kuhnhauser, P., Gotz, J., Kepser, L.J., Lotze, M., Grabe, H.J., Volzke, H., Leehr, E.J., Meinert, S., Opel, N., Richers, S., Stroh, A., Daun, S., Tittgemeyer, M., Uphaus, T., Steffen, F., Zipp, F., Gross, J., Groppa, S., Dannlowski, U., Nitsch, R., and Vogt, J. (2024). Altered cortical synaptic lipid signaling leads to intermediate phenotypes of mental disorders. Mol Psychiatry29, 3537-3552. 10.1038/s41380-024-02598-2.
- Tüscher, O., Muthuraman, M., Horstmann, J.P., Horta, G., Radyushkin, K., Baumgart, J., Sigurdsson, T., Endle, H., Ji, H.C., Kuhnhäuser, P., Götz, J., Kepser, L.J., Lotze, M., Grabe, H.J., Völzke, H., Leehr, E.J., Meinert, S., Opel, N., Richers, S., Stroh, A., Daun, S., Tittgemeyer, M., Uphaus, T., Steffen, F., Zipp, F., Gross, J., Groppa, S., Dannlowski, U., Nitsch, R., and Vogt, J. (2024). Altered cortical synaptic lipid signaling leads to intermediate phenotypes of mental disorders. Mol Psychiatr10.1038/s41380-024-02598-2. 10.1038/s41380-024-02598-2.
Achim Tresch
- Muller, J.M., Moos, K., Baar, T., Maier, K.C., Zumer, K., and Tresch, A. (2024). Nuclear export is a limiting factor in eukaryotic mRNA metabolism. PLoS Comput Biol20, e1012059. 10.1371/journal.pcbi.1012059.
To top
Aleksandra Trifunovic
- Geissen, S., Braumann, S., Adler, J., Nettersheim, F.S., Mehrkens, D., Hof, A., Guthoff, H., von Stein, P., Witkowski, S., Gerdes, N., Tellkamp, F., Kruger, M., Isermann, L., Trifunovic, A., Bunck, A.C., Mollenhauer, M., Winkels, H., Adam, M., Klinke, A., Buch, G., Ten Cate, V., Hellmich, M., Kelm, M., Rudolph, V., Wild, P.S., Rosenkranz, S., and Baldus, S. (2024). Inhibition of myeloperoxidase to treat left ventricular dysfunction in non-ischaemic cardiomyopathy. Eur J Heart Fail26, 2269-2281. 10.1002/ejhf.3435.
- Moschandrea, C., Kondylis, V., Evangelakos, I., Herholz, M., Schneider, F., Schmidt, C., Yang, M., Ehret, S., Heine, M., Jaeckstein, M.Y., Szczepanowska, K., Schwarzer, R., Baumann, L., Bock, T., Nikitopoulou, E., Brodesser, S., Kruger, M., Frezza, C., Heeren, J., Trifunovic, A., and Pasparakis, M. (2024). Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes. Nature625, 385-392. 10.1038/s41586-023-06857-0.
- Pham, T.C.P., Raun, S.H., Havula, E., Henriquez-Olguin, C., Rubalcava-Gracia, D., Frank, E., Fritzen, A.M., Jannig, P.R., Andersen, N.R., Kruse, R., Ali, M.S., Irazoki, A., Halling, J.F., Ringholm, S., Needham, E.J., Hansen, S., Lemminger, A.K., Schjerling, P., Petersen, M.H., de Almeida, M.E., Jensen, T.E., Kiens, B., Hostrup, M., Larsen, S., Ortenblad, N., Hojlund, K., Kjaer, M., Ruas, J.L., Trifunovic, A., Wojtaszewski, J.F.P., Nielsen, J., Qvortrup, K., Pilegaard, H., Richter, E.A., and Sylow, L. (2024). The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms. Nat Commun15, 9826. 10.1038/s41467-024-54183-4.
- Popovic, M., Isermann, L., Geissen, S., Senft, K., Georgomanolis, T., Baldus, S., Frezza, C., and Trifunovic, A. (2024). Tissue-specific adaptations to cytochrome c oxidase deficiency shape physiological outcomes. Biochim Biophys Acta Mol Basis Dis1871, 167567. 10.1016/j.bbadis.2024.167567.
- Rosing, S., Ullrich, F., Meisterfeld, S., Schmidt, F., Mlitzko, L., Croon, M., Nattrass, R.G., Eberl, N., Mahlberg, J., Schlee, M., Wieland, A., Simon, P., Hilbig, D., Reuner, U., Rapp, A., Bremser, J., Mirtschink, P., Drukewitz, S., Zillinger, T., Beissert, S., Paeschke, K., Hartmann, G., Trifunovic, A., Bartok, E., and Gunther, C. (2024). Chronic endoplasmic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release. Nat Commun15, 1534. 10.1038/s41467-024-45535-1.
To top
Mirka Uhlirova
- Stankovic, D., Tain, L.S., and Uhlirova, M. (2024). Xrp1 governs the stress response program to spliceosome dysfunction. Nucleic Acids Res52, 2093-2111. 10.1093/nar/gkae055.
Silvana Valtcheva
- Yang, M., Keller, D., Dobolyi, A., and Valtcheva, S. (2025). The lateral thalamus: a bridge between multisensory processing and naturalistic behaviors. Trends Neurosci48, 33-46. 10.1016/j.tins.2024.11.005.
David Vilchez
- Alirzayeva, H., Loureiro, R., Koyuncu, S., Hommen, F., Nabawi, Y., Zhang, W.H., Dao, T.T.P., Wehrmann, M., Lee, H.J., and Vilchez, D. (2024). ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes. Cell Rep43, 114626. 10.1016/j.celrep.2024.114626.
- Charura, N., Llamas, E., De Quattro, C., Vilchez, D., Nowack, M.K., and Zuccaro, A. (2024). Root cap cell corpse clearance limits microbial colonization in Arabidopsis thaliana. Elife13. 10.7554/eLife.96266.
- Koyuncu, S., Loureiro, R., Lee, H.J., Wagle, P., Krueger, M., and Vilchez, D. (2024). Author Correction: Rewiring of the ubiquitinated proteome determines ageing in C. elegans. Nature626, E20. 10.1038/s41586-024-07168-8.
- Li, X., Hernandez, I., Koyuncu, S., Kis, B., Haggblad, M., Lidemalm, L., Abbas, A.A., Bendeguz, S., Goblos, A., Brautigam, L., Lucas, J.J., Carreras-Puigvert, J., Huhn, D., Pircs, K., Vilchez, D., and Fernandez-Capetillo, O. (2024). The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARgamma. Ebiomedicine103, 105124. 10.1016/j.ebiom.2024.105124.
Johannes Vogt
- Fischer, C., Schreiber, Y., Nitsch, R., Vogt, J., Thomas, D., Geisslinger, G., and Tegeder, I. (2024). Lysophosphatidic Acid Receptors LPAR5 and LPAR2 Inversely Control Hydroxychloroquine-Evoked Itch and Scratching in Mice. Int J Mol Sci25. 10.3390/ijms25158177.
- Tuscher, O., Muthuraman, M., Horstmann, J.P., Horta, G., Radyushkin, K., Baumgart, J., Sigurdsson, T., Endle, H., Ji, H., Kuhnhauser, P., Gotz, J., Kepser, L.J., Lotze, M., Grabe, H.J., Volzke, H., Leehr, E.J., Meinert, S., Opel, N., Richers, S., Stroh, A., Daun, S., Tittgemeyer, M., Uphaus, T., Steffen, F., Zipp, F., Gross, J., Groppa, S., Dannlowski, U., Nitsch, R., and Vogt, J. (2024). Altered cortical synaptic lipid signaling leads to intermediate phenotypes of mental disorders. Mol Psychiatry29, 3537-3552. 10.1038/s41380-024-02598-2.
- Tüscher, O., Muthuraman, M., Horstmann, J.P., Horta, G., Radyushkin, K., Baumgart, J., Sigurdsson, T., Endle, H., Ji, H.C., Kuhnhäuser, P., Götz, J., Kepser, L.J., Lotze, M., Grabe, H.J., Völzke, H., Leehr, E.J., Meinert, S., Opel, N., Richers, S., Stroh, A., Daun, S., Tittgemeyer, M., Uphaus, T., Steffen, F., Zipp, F., Gross, J., Groppa, S., Dannlowski, U., Nitsch, R., and Vogt, J. (2024). Altered cortical synaptic lipid signaling leads to intermediate phenotypes of mental disorders. Mol Psychiatr10.1038/s41380-024-02598-2. 10.1038/s41380-024-02598-2.
Silvia von Karstedt
- Berndt, C., Alborzinia, H., Amen, V.S., Ayton, S., Barayeu, U., Bartelt, A., Bayir, H., Bebber, C.M., Birsoy, K., Bottcher, J.P., Brabletz, S., Brabletz, T., Brown, A.R., Brune, B., Bulli, G., Bruneau, A., Chen, Q., DeNicola, G.M., Dick, T.P., Distefano, A., Dixon, S.J., Engler, J.B., Esser-von Bieren, J., Fedorova, M., Friedmann Angeli, J.P., Friese, M.A., Fuhrmann, D.C., Garcia-Saez, A.J., Garbowicz, K., Gotz, M., Gu, W., Hammerich, L., Hassannia, B., Jiang, X., Jeridi, A., Kang, Y.P., Kagan, V.E., Konrad, D.B., Kotschi, S., Lei, P., Le Tertre, M., Lev, S., Liang, D., Linkermann, A., Lohr, C., Lorenz, S., Luedde, T., Methner, A., Michalke, B., Milton, A.V., Min, J., Mishima, E., Muller, S., Motohashi, H., Muckenthaler, M.U., Murakami, S., Olzmann, J.A., Pagnussat, G., Pan, Z., Papagiannakopoulos, T., Pedrera Puentes, L., Pratt, D.A., Proneth, B., Ramsauer, L., Rodriguez, R., Saito, Y., Schmidt, F., Schmitt, C., Schulze, A., Schwab, A., Schwantes, A., Soula, M., Spitzlberger, B., Stockwell, B.R., Thewes, L., Thorn-Seshold, O., Toyokuni, S., Tonnus, W., Trumpp, A., Vandenabeele, P., Vanden Berghe, T., Venkataramani, V., Vogel, F.C.E., von Karstedt, S., Wang, F., Westermann, F., Wientjens, C., Wilhelm, C., Wolk, M., Wu, K., Yang, X., Yu, F., Zou, Y., and Conrad, M. (2024). Ferroptosis in health and disease. Redox Biol75, 103211. 10.1016/j.redox.2024.103211.
Henning Walczak
- Albert, M.C., Uranga-Murillo, I., Arias, M., De Miguel, D., Pena, N., Montinaro, A., Varanda, A.B., Theobald, S.J., Areso, I., Saggau, J., Koch, M., Liccardi, G., Peltzer, N., Rybniker, J., Hurtado-Guerrero, R., Merino, P., Monzon, M., Badiola, J.J., Reindl-Schwaighofer, R., Sanz-Pamplona, R., Cebollada-Solanas, A., Megyesfalvi, Z., Dome, B., Secrier, M., Hartmann, B., Bergmann, M., Pardo, J., and Walczak, H. (2024). Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality. Cell Death Differ31, 544-557. 10.1038/s41418-024-01278-6.
- Chen, Y.G., Rieser, E., Bhamra, A., Surinova, S., Kreuzaler, P., Ho, M.H., Tsai, W.C., Peltzer, N., de Miguel, D., and Walczak, H. (2024). LUBAC enables tumor-promoting LTbeta receptor signaling by activating canonical NF-kappaB. Cell Death Differ31, 1267-1284. 10.1038/s41418-024-01355-w.
- Ibruli, O., Rose, F., Beleggia, F., Schmitt, A., Cartolano, M., Fernandez, L.T., Saggau, J., Bonasera, D., Kiljan, M., Gozum, G., Lichius, L., Cai, J., Niu, L.N., Caiaffa, M.I., Herter, J.M., Walczak, H., Liccardi, G., Grull, H., Buttner, R., Bosco, G., George, J., Thomas, R.K., Bozek, K., Reinhardt, H.C., and Herter-Sprie, G.S. (2024). A novel mouse model recapitulating the MMR-defective SCLC subtype uncovers an actionable sensitivity to immune checkpoint blockade. J Cancer Res Clin Oncol150, 496. 10.1007/s00432-024-05942-9.
- Kabiljo, J., Theophil, A., Homola, J., Renner, A.F., Sturzenbecher, N., Ammon, D., Zirnbauer, R., Stang, S., Tran, L., Laengle, J., Kulu, A., Chen, A., Fabits, M., Atanasova, V.S., Pusch, O., Weninger, W., Walczak, H., Herndler Brandstetter, D., Egger, G., Dolznig, H., Kusienicka, A., Farlik, M., and Bergmann, M. (2024). Cancer-associated fibroblasts shape early myeloid cell response to chemotherapy-induced immunogenic signals in next generation tumor organoid cultures. J Immunother Cancer12. 10.1136/jitc-2024-009494.
- Kelepouras, K., Saggau, J., Varanda, A.B., Zrilic, M., Kiefer, C., Rakhsh-Khorshid, H., Lisewski, I., Uranga-Murillo, I., Arias, M., Pardo, J., Tonnus, W., Linkermann, A., Annibaldi, A., Walczak, H., and Liccardi, G. (2024). The importance of murine phospho-MLKL-S345 in situ detection for necroptosis assessment in vivo. Cell Death Differ31, 897-909. 10.1038/s41418-024-01313-6.
- Oda, H., Manthiram, K., Chavan, P.P., Rieser, E., Veli, O., Kaya, O., Rauch, C., Nakabo, S., Kuehn, H.S., Swart, M., Wang, Y., Celik, N.I., Molitor, A., Ziaee, V., Movahedi, N., Shahrooei, M., Parvaneh, N., Alipour-Olyei, N., Carapito, R., Xu, Q., Preite, S., Beck, D.B., Chae, J.J., Nehrebecky, M., Ombrello, A.K., Hoffmann, P., Romeo, T., Deuitch, N.T., Matthiasardottir, B., Mullikin, J., Komarow, H., Stoddard, J., Niemela, J., Dobbs, K., Sweeney, C.L., Anderton, H., Lawlor, K.E., Yoshitomi, H., Yang, D., Boehm, M., Davis, J., Mudd, P., Randazzo, D., Tsai, W.L., Gadina, M., Kaplan, M.J., Toguchida, J., Mayer, C.T., Rosenzweig, S.D., Notarangelo, L.D., Iwai, K., Silke, J., Schwartzberg, P.L., Boisson, B., Casanova, J.L., Bahram, S., Rao, A.P., Peltzer, N., Walczak, H., Lalaoui, N., Aksentijevich, I., and Kastner, D.L. (2024). Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency. Nat Immunol25, 764-777. 10.1038/s41590-024-01817-w.
- Ruiz Seco, M.P., Pano Pardo, J.R., Schoergenhofer, C., Dings, C., Lehr, T., Herth, F., Krendyukov, A., Straub, C., Kappler, M., Jilma, B., Fricke, H., Pardo, J., de Miguel, D., Thiemann, M., Bergmann, M., Walczak, H., and Hoeger, T. (2024). Efficacy and safety of asunercept, a CD95L-selective inhibitor, in hospitalised patients with moderate-to-severe COVID-19: ASUNCTIS, a multicentre, randomised, open-label, controlled, phase 2 trial. Eclinicalmedicine77, 102879. 10.1016/j.eclinm.2024.102879.
- Teague, H.C., Lefevre, C., Rieser, E., Wolfram, L., de Miguel, D., Patricio de Oliveira, D., Oliveira, M., Mansur, D.S., Irigoyen, N., Walczak, H., and Ferguson, B.J. (2024). LUBAC is required for RIG-I sensing of RNA viruses. Cell Death Differ31, 28-39. 10.1038/s41418-023-01233-x.
- Valdez Capuccino, L., Kleitke, T., Szokol, B., Svajda, L., Martin, F., Bonechi, F., Kreko, M., Azami, S., Montinaro, A., Wang, Y., Nikolov, V., Kaiser, L., Bonasera, D., Saggau, J., Scholz, T., Schmitt, A., Beleggia, F., Reinhardt, H.C., George, J., Liccardi, G., Walczak, H., Tovari, J., Bragelmann, J., Montero, J., Sos, M.L., Orfi, L., and Peltzer, N. (2024). CDK9 inhibition as an effective therapy for small cell lung cancer. Cell Death Dis15, 345. 10.1038/s41419-024-06724-4.
- Veli, O., Kaya, O., Varanda, A.B., Hildebrandt, X., Xiao, P., Estornes, Y., Poggenberg, M., Wang, Y., Pasparakis, M., Bertrand, M.J.M., Walczak, H., Annibaldi, A., Cardozo, A.K., and Peltzer, N. (2024). RIPK1 is dispensable for cell death regulation in beta-cells during hyperglycemia. Mol Metab87, 101988. 10.1016/j.molmet.2024.101988.
- Vringer, E., Heilig, R., Riley, J.S., Black, A., Cloix, C., Skalka, G., Montes-Gomez, A.E., Aguado, A., Lilla, S., Walczak, H., Gyrd-Hansen, M., Murphy, D.J., Huang, D.T., Zanivan, S., and Tait, S.W. (2024). Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-kappaB-mediated inflammatory response. EMBO J43, 904-930. 10.1038/s44318-024-00044-1.
To top
Rudolf Wiesner
- Berwanger, C., Terres, D., Pesta, D., Eggers, B., Marcus, K., Wittig, I., Wiesner, R.J., Schroder, R., and Clemen, C.S. (2024). Immortalised murine R349P desmin knock-in myotubes exhibit a reduced proton leak and decreased ADP/ATP translocase levels in purified mitochondria. Eur J Cell Biol103, 151399. 10.1016/j.ejcb.2024.151399.
- Boix, J., Knuever, J., Niehoff, N., Sen, A., Pla-Martin, D., Baris, O.R., Etich, J., Brachvogel, B., Kaul, H., Isbrandt, D., Soroka, E., Bazzi, H., Wenger, R.H., Giavalisco, P., and Wiesner, R.J. (2024). Constitutive HIF-1alpha Expression in the Epidermis Fuels Proliferation and Is Essential for Effective Barrier Formation. J Invest Dermatol10.1016/j.jid.2024.09.022. 10.1016/j.jid.2024.09.022.
- Pass, T., Ricke, K.M., Hofmann, P., Chowdhury, R.S., Nie, Y., Chinnery, P., Endepols, H., Neumaier, B., Carvalho, A., Rigoux, L., Steculorum, S.M., Prudent, J., Riemer, T., Aswendt, M., Liss, B., Brachvogel, B., and Wiesner, R.J. (2024). Preserved striatal innervation maintains motor function despite severe loss of nigral dopaminergic neurons. Brain147, 3189-3203. 10.1093/brain/awae089.
- Reiter, L., Niehoff, N., Weiland, D., Helbig, D., Eming, S.A., Krieg, T., Etich, J., Brachvogel, B., Wiesner, R.J., and Knuever, J. (2024). Mitochondrial DNA mutations attenuate Bleomycin-induced dermal fibrosis by inhibiting differentiation into myofibroblasts. Matrix Biol132, 72-86. 10.1016/j.matbio.2024.07.002.
To top
Andreas Wodarz
- Kim, S., Shahab, J., Vogelsang, E., and Wodarz, A. (2024). Re-assessment of the subcellular localization of Bazooka/Par-3 in Drosophila: no evidence for localization to the nucleus and the neuromuscular junction. Biol Open13. 10.1242/bio.060544.
To top
Thomas Wunderlich
- Engstrom Ruud, L., Font-Girones, F., Zajdel, J., Kern, L., Teixidor-Deulofeu, J., Manneras-Holm, L., Carreras, A., Becattini, B., Bjorefeldt, A., Hanse, E., Fenselau, H., Solinas, G., Bruning, J.C., Wunderlich, T.F., Backhed, F., and Ruud, J. (2024). Activation of GFRAL(+) neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor. Cell Rep43, 113960. 10.1016/j.celrep.2024.113960.
- Knopp, T., Jung, R., Wild, J., Bochenek, M.L., Efentakis, P., Lehmann, A., Bieler, T., Garlapati, V., Richter, C., Molitor, M., Perius, K., Finger, S., Lagrange, J., Ghasemi, I., Zifkos, K., Kommoss, K.S., Masri, J., Reissig, S., Randriamboavonjy, V., Wunderlich, T., Hovelmeyer, N., Weber, A.N.R., Mufazalov, I.A., Bosmann, M., Bechmann, I., Fleming, I., Oelze, M., Daiber, A., Munzel, T., Schafer, K., Wenzel, P., Waisman, A., and Karbach, S. (2024). Myeloid cell-derived interleukin-6 induces vascular dysfunction and vascular and systemic inflammation. Eur Heart J Open4, oeae046. 10.1093/ehjopen/oeae046.
- Ruud, L.E., Font-Girones, F., Zajdel, J., Kern, L., Teixidor-Deulofeu, J., Manneräs-Holm, L., Carreras, A., Becattini, B., Björefeldt, A., Hanse, E., Fenselau, H., Solinas, G., Bruening, J.C., Wunderlich, T.F., Backhed, F., and Ruud, J. (2024). Activation of GFRAL plus neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor. Cell Rep43. 10.1016/j.celrep.2024.113960.
To top
Branko Zevnik
- Aich, A., Boshnakovska, A., Witte, S., Gall, T., Unthan-Fechner, K., Yousefi, R., Chowdhury, A., Dahal, D., Methi, A., Kaufmann, S., Silbern, I., Prochazka, J., Nichtova, Z., Palkova, M., Raishbrook, M., Koubkova, G., Sedlacek, R., Troder, S.E., Zevnik, B., Riedel, D., Michanski, S., Mobius, W., Strobel, P., Luchtenborg, C., Giavalisco, P., Urlaub, H., Fischer, A., Brugger, B., Jakobs, S., and Rehling, P. (2024). Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver. Nat Commun15, 6914. 10.1038/s41467-024-51109-y.
- Jerchow, B., Schenkel, J., Nagel-Riedasch, S., Zevnik, B., and Buch, T. (2024). Zuchtplanung bei Labormäusen. GV-SOLAS.
To top
Gabriele Zaffagnini
- Zaffagnini, G., Cheng, S.Y., Salzer, M.C., Pernaute, B., Duran, J.M., Irimia, M., Schuh, M., and Böke, E. (2024). Mouse oocytes sequester aggregated proteins in degradative super-organelles. Cell 187. 10.1016/j.cell.2024.01.031.
To top