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Adam Antebi

• Annibal A, Tam H, Latza C, Antebi A (2019). Comparison of ESI-MS/MS and APCI-MS methods for the quantification of folic acid analogs in C. elegans. J Mass Spectrom. 2019 Apr;54(4):316-327. doi: 10.1002/jms.4337
• Antebi A (2019). Developmental Timing: Honey, I Reprogrammed the Kids. Curr Biol. 2019 Jun 3;29(11):R420-R422. doi: 10.1016/j.cub.2019.04.054 
• Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB, Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, Hoppe T, Kaeberlein M, Katajisto P, Kennedy BK, Lal U, Martin-Villalba A, Moskalev AA, Ozerov I, Petr MA, Reason, Rubinsztein DC, Tyshkovskiy A, Vanhaelen Q, Zhavoronkov A, Scheibye-Knudsen M (2019). Latest advances in aging research and drug discovery. Aging (Albany NY). 2019 Nov 21;11(22):9971-9981. doi: 10.18632/aging.102487. Epub 2019 Nov 21. PMID: 31770722
• Calimport SRG, Bentley BL, Stewart CE, Pawelec G, Scuteri A, Vinciguerra M, Slack C, Chen D, Harries LW, Marchant G, Fleming GA, Conboy M, Antebi A, Small GW, Gil J, Lakatta EG, Richardson A, Rosen C, Nikolich K, Wyss-Coray T, Steinman L, Montine T, de Magalhães JP, Campisi J, Church G (2019). To help aging populations, classify organismal senescence. Science. 2019 Nov 1;366(6465):576-578. doi: 10.1126/science.aay7319    
• De-Souza EA, Camara H, Salgueiro WG, Moro RP, Knittel TL, Tonon G, Pinto S, Pinca APF, Antebi A, Pasquinelli AE, Massirer KB, Mori MA (2019). RNA interference may result in unexpected phenotypes in Caenorhabditis elegans. Nucleic Acids Res. 2019 May 7;47(8):3957-3969. doi: 10.1093/nar/gkz154      
• Dolfi L, Ripa R, Antebi A, Valenzano DR, Cellerino A (2019). Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology. Evodevo. 2019 Nov 8;10:29. doi: 10.1186/s13227-019-0142-5. eCollection 2019  
• Fischer J, Gutièrrez S, Ganesan R, Calabrese C, Ranjan R, Cildir G, Hos NJ, Rybniker J, Wolke M, Fries JWU, Tergaonkar V, Plum G, Antebi A, Robinson N (2019). Leptin signaling impairs macrophage defenses against Salmonella Typhimurium. Proc Natl Acad Sci USA. 2019 Aug 13;116(33):16551-16560. doi: 10.1073/pnas.1904885116. Epub 2019 Jul 26     
• Guerra BA, Brandão BB, Pinto SS, Salgueiro WG, De-Souza EA, Reis FCG, Batista TM, Cavalcante-Silva V, D'Almeida V, Castilho BA, Carneiro EM, Antebi A, Festuccia WT, Mori MA (2019). Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects. Mol Metab. 2019 Nov;29:124-135. doi:10.1016/j.molmet.2019.08.017. Epub 2019 Aug 28
• Lesanpezeshki L, Hewitt JE, Laranjeiro R, Antebi A, Driscoll M, Szewczyk NJ, Blawzdziewicz J, Lacerda CMR, Vanapalli SA (2019). Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans. Sci Rep. 2019 Oct 23;9(1):15246. doi: 10.1038/s41598-019-51608-9
• Nakamura S, Oba M, Suzuki M, Takahashi A, Yamamuro T, Fujiwara M, Ikenaka K, Minami S, Tabata N, Yamamoto K, Kubo S, Tokumura A, Akamatsu K, Miyazaki Y, Kawabata T, Hamasaki M, Fukui K, Sango K, Watanabe Y, Takabatake Y, Kitajima TS, Okada Y, Mochizuki H, Isaka Y, Antebi A, Yoshimori T (2019). Suppression of autophagic activity by Rubicon is a signature of aging. Nat Commun. 2019 Feb 19;10(1):847. doi: 10.1038/s41467-019-08729-6 
• Zhou Y, Wang X, Song M, He Z, Cui G, Peng G, Dieterich C, Antebi A, Jing N, Shen Y (2019). A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing. Nat Commun. 2019 Oct 23;10(1):4827. doi: 10.1038/s41467-019-12821-2

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Hisham Bazzi

• Gilmore, A.C., Carrasco, E., Bazzi, H., Christiano, A., and Jahoda, C.A. (2019). Characterisation of the mouse embryonic dermis and timing and control of adipogenic cell fate. J Invest Dermatol139, S160-S160.

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Thomas Benzing

• Assady S, Benzing T, Kretzler M, Skorecki KL (2019). Glomerular podocytes in kidney health and disease. Lancet. 2019 Mar 2;393(10174):856-858. doi: 10.1016/S0140-6736(18)33000-9   
• Braun F, Blomberg L, Brodesser S, Liebau MC, Schermer B, Benzing T, Kurschat CE (2019). Enzyme Replacement Therapy Clears Gb3 Deposits from a Podocyte Cell Culture Model of Fabry Disease but Fails to Restore Altered Cellular Signaling. Cell Physiol Biochem. 2019;52(5):1139-1150. doi: 10.33594/000000077
• Braun F, Suarez V, Dinter J, Haneder S, Quaas A, Benzing T, Nierhoff D, Müller RU (2019). Successful use of TNFα blockade in a severe case of idiopathic non-granulomatous ulcerative jejunoileitis associated with thrombotic thrombocytopenic purpura. BMJ Open Gastroenterol. 2019 Feb 8;6(1):e000252. doi: 10.1136/bmjgast-2018-000252. eCollection 2019
• Brinkkoetter PT, Bork T, Salou S, Liang W, Mizi A, Özel C, Koehler S. Hagmann HH, Ising C, Kuczkowski A, Schnyder S, Abed A, Schermer B, Benzing T, Kretz O, Puelles VG, Lagies S, Schlimpert M, Kammerer B, Handschin C, Schell C, Huber TB (2019). Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics. Cell Rep. 2019 Apr 30;27(5):1551-1566.e5. doi: 10.1016/j.celrep.2019.04.012
• Burgmaier K, Kilian S, Bammens B, Benzing T, Billing H, Buscher A, Galiano M, Grundmann F, Klaus G, Mekahli D, Michel-Calemard L, Milosevski-Lomic G, Ranchin B, Sauerstein K, Schaefer S, Shroff R, Sterenborg R, Verbeeck S, Weber LT, Wicher D, Wühl E, Dötsch J, Schaefer F, Liebau MC (2019). Clinical courses and complications of young adults with Autosomal Recessive Polycystic Kidney Disease (ARPKD). Sci Rep. 2019 May 28;9(1):7919. doi: 10.1038/s41598-019-43488-w
• Esmaillie, R., Ignarski, M., Bohl, K., Kruger, T., Ahmad, D., Seufert, L., Schermer, B., Benzing, T., Muller, R.U., and Fabretti, F. (2019). Activation of Hypoxia-Inducible Factor Signaling Modulates the RNA Protein Interactome in Caenorhabditis elegans. iScience 22, 466-476. 10.1016/j.isci.2019.11.039.
• Heess, A., Pickert, L., Meyer, A.M., Becker, I., Müller, F., Noetzel, N., Rarek, M., Burst, V., Brinkkötter, P.T., Pilotto, A., Benzing, T., and Nelles, M.C.P. (2019). Comprehensive Geriatric Assessment-based Prognosis Estimation and Subjective Quality of Life of elderly hospitalized Patients. Zeitschrift für Gerontologie und Geriatrie 52, S149-S150.
• Ignarski M, Rill C, Kaiser RWJ, Kaldirim M, Neuhaus R, Esmaillie R, Li X, Klein C, Bohl K, Petersen M, Frese CK, Höhne M, Atanassov I, Rinschen MM, Höpker K, Schermer B, Benzing T, Dietrich C, Fabretti F, Müller RU (2019). The RNA-protein interactome of differentiated kidney tubular epithelial cells. J Am Soc Nephrol. 2019 Apr;30(4):564-576. doi: 10.1681/ASN.2018090914. Epub 2019 Mar 13
• Jain M, Kaiser RWJ, Bohl K, Hoehne M, Göbel H, Bartram MP, Habbig S, Müller RU, Fogo AB, Benzing T, Schermer B, Höpker K, Slaats GG (2019). Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis. Kidney Int. 2019 Apr;95(4):846-858. doi: 10.1016/j.kint.2018.10.034. Epub 2019 Feb 13
• Kaiser RWJ, Ignarski M, Nostrand ELV, Frese CK, Jain M, Cukoski S, Heinen H, Schaechter M, Seufert L, Bunte K, Frommolt P, Keller P, Helm M, Bohl K, Höhne M, Schermer B, Benzing T, Höpker K, Dietrich C, Yeo GW, Müller RU, Fabretti F (2019). A protein-RNA interaction atlas of the ribosome biogenesis factor AATF. Sci Rep. 2019 Jul 30;9(1):11071. doi: 10.1038/s41598-019-47552-3
• Meyer AM, Becker I, Siri G, Brinkkötter PT, Benzing T, Pilotto A, Polidori MC (2019). New associations of the Multidimensional Prognostic Index. Z Gerontol Geriatr. 2019 Aug;52(5):460-467. doi: 10.1007/s00391-018-01471-6. Epub 2018 Nov 7
• Meyer AM, Siri G, Becker I, Betz T, Bodecker AW, Robertz JW, Krause O, Benzing T, Pilotto A, Polidori MC (2019). The Multidimensional Prognostic Index in general practice: One-year follow-up study. Int J Clin Pract. 2019 Aug 13:e13403. doi: 10.1111/ijcp.13403. [Epub ahead of print]
• Phipps EA, Thadhani R, Benzing T, Karumanchi SA (2019). Pre-eclampsia: pathogenesis, novel diagnostics and therapies. Nat Rev Nephrol. 2019 May;15(5):275-289. doi: 10.1038/s41581-019-0119-6
• Phipps, E.A., Thadhani, R., Benzing, T., and Karumanchi, S.A. (2019). Author Correction: Pre-eclampsia: pathogenesis, novel diagnostics and therapies. Nat Rev Nephrol 15, 386. 10.1038/s41581-019-0156-1.   
• Schermer B, Benzing T (2019). [Genome Editing with CRISPR/Cas9: First Steps Towards a new Era in Medicine?]. Dtsch Med Wochenschr. 2019 Feb;144(4):276-281. doi: 10.1055/a-0759-7180. Epub 2019 Feb 13 
• Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM (2019). The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2019 Feb;95(2):333-349. doi: 10.1016/j.kint.2018.08.037. Epub 2018 Dec 3
• Völker LA, Burkert K, Scholten N, Grundmann F, Kurschat C, Benzing T, Hampl J, Becker JU, Müller RU (2019). A case report of recurrent membranoproliferative glomerulonephritis after kidney  transplantation due to ventriculoatrial shunt infection. BMC Nephrol. 2019 Aug 5;20(1):296. doi: 10.1186/s12882-019-1472-1
• Völker LA, Ehren R, Grundmann F, Benzing T, Weber LT, Brinkkötter PT (2019). A newly established clinical registry of minimal change disease and focal and segmental glomerulosclerosis in Germany. Nephrol Dial Transplant. 2019 Dec 1;34(12):1983-1986. doi: 10.1093/ndt/gfz046
• Wöstmann F, Müller RU, Göbel H, Benzing T, Becker JU, Bartram MP (2019). Case report: a peculiar glomerulopathy in a patient suffering from nephrotic syndrome. BMC Nephrol. 2019 Aug 22;20(1):326. doi: 10.1186/s12882-019-1478-8

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Matteo Bergami

• Engelhardt, E., Göbel, J., Jahn, H.M., Altmüller, J., and Bergami, M. (2019). Genetic manipulation of NEMO reveals glial cell type-specific effects of NF-κB activation following brain injury. Glia 67, E557-E558.
• Rangaraju V, Lewis TL Jr, Hirabayashi Y, Bergami M, Motori E, Cartoni R, Kwon SK, Courchet J (2019). Pleiotropic Mitochondria: The Influence of Mitochondria on Neuronal Development and Disease. J Neurosci. 2019 Oct 16;39(42):8200-8208. doi: 10.1523/JNEUROSCI.1157-19.2019   
• Ren SQ, Li Z, Lin S, Bergami M, Shi SH (2019). Precise Long-Range Microcircuit-to-Microcircuit Communication Connects the Frontal and Sensory Cortices in the Mammalian Brain. Neuron. 2019 Oct 23;104(2):385-401.e3. doi: 10.1016/j.neuron.2019.06.028. Epub 2019 Jul 29  
• Riedemann S, Sutor B, Bergami M, Riedemann T (2019). Gad1-promotor-driven GFP expression in non-GABAergic neurons of the nucleus endopiriformis in a transgenic mouse line. J Comp Neurol. 2019 Oct 1;527(14):2215-2232. doi: 10.1002/cne.24673. Epub 2019 Mar 20  
• Sprenger HS, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2019). Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 2019 Jan;11(1). pii: e9288. doi: 10.15252/emmm.201809288  
• Wani, G.A., Wendler, S., Sprenger, H.G., Göbel, J., Seeger, J., Fernando, B., Frese, C., Langer, T., and Bergami, M.(2019). The mitochondrial peptidase YME1L controls the early proliferative steps of adult neurogenesis. Glia 67, E511-E512.
• Wendler, S.M.V., Wani, G., Göbel, J., Conzelmann, K.K., Lie, D.C., and Bergami, M. (2019). Role of mitochondrial fusion dynamics in adult hippocampal NSC lineage progression. Glia 67, E508-E508.

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Andreas Beyer

• Debès C, Leote AC, Beyer A (2019). Computational approaches for the systematic analysis of ageing-associated molecular alterations (Review). Drug Discov Tod. Disease Mod. 27:51-59; https://doi.org/10.1016/j.ddmod.2019.03.003  
• Hahn O, Drews LF, Nguyen A, Tatsuta T, Gkioni L, Hendrich O, Zhang Q, Langer T, Pletcher S, Wakelam MJO, Beyer A, Grönke S, Partridge L (2019). A nutritional memory effect counteracts the benefits of dietary restriction in old mice. Nat Metab. 1059–1073  
• Lapin D, Kovacova V, Sun X, Dongus JA, Bhandari D, von Born P, Bautor J, Guarneri N, Rzemieniewski J, Stuttmann J, Beyer A, Parker JE (2019). A coevolved EDS1-SAG101-NRG1 module mediates cell death signaling by TIR-domain immune receptors. Plant Cell. 2019 Oct;31(10):2430-2455. doi: 10.1105/tpc.19.00118. Epub 2019 Jul 16  
• Shao W, Guo T, Toussaint NC, Xue P, Wagner U, Li L, Charmpi K, Zhu Y, Wu J, Buljan M, Sun R, Rutishauser D, Hermanns T, Fankhauser CD, Poyet C, Ljubicic J, Rupp N, Rüschoff JH, Zhong Q, Beyer A, Ji J, Collins BC, Liu Y, Rätsch G, Wild PJ, Aebersold R (2019). Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins. Nat Commun. 2019 Jun 7;10(1):2524. doi: 10.1038/s41467-019-10513-5  
• Soste M, Charmpi K, Lampert F, Gerez JA, van Oostrum M, Malinovska L, Boersema PJ, Prymaczok NC, Riek R, Peter M, Vanni S, Beyer A, Picotti P (2019). Proteomics-based monitoring of pathway activity reveals that blocking diacylglycerol biosynthesis rescues from alpha-synuclein toxicity. Cell Syst. 2019 Sep 25;9(3):309-320.e8. doi: 10.1016/j.cels.2019.07.010. Epub 2019 Sep 11  
• Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM (2019). The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2019 Feb;95(2):333-349. doi: 10.1016/j.kint.2018.08.037. Epub 2018 Dec 3 

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Susanne Brodesser

• Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling JE, Dodzian J, Lagerborg KA, Vargas NE, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano DR, Kurian L (2019). Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep. 2019 Apr;20(4). pii: e47407. doi: 10.15252/embr.201847407. Epub 2019 Mar 18
• Braun F, Blomberg L, Brodesser S, Liebau MC, Schermer B, Benzing T, Kurschat CE (2019). Enzyme Replacement Therapy Clears Gb3 Deposits from a Podocyte Cell Culture Model of Fabry Disease but Fails to Restore Altered Cellular Signaling. Cell Physiol Biochem. 2019;52(5):1139-1150. doi: 10.33594/000000077
• Farowski F, Solbach P, Tsakmaklis A, Brodesser S, Cruz Aguilar MR, Cornely OA, Dettmer K, Higgins PG, Suerbaum S, Jazmati N, Oefner PJ, Vehreschild MJGT (2019). Potential biomarkers to predict outcome of faecal microbiota transfer for recurrent Clostridioides difficile infection. Dig Liver Dis. 2019 Jul;51(7):944-951. doi: 10.1016/j.dld.2019.01.012. Epub 2019 Jan 26
• Murru S, Hess S, Barth E, Almajan ER, Schatton D, Hermans S, Brodesser S, Langer T, Kloppenburg P, Rugarli EI (2019). Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019 Aug;67(8):1526-1541. doi: 10.1002/glia.23626. Epub 2019 Apr 16
• Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin P, Baraibar MA, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M (2019). Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy. EMBO J. 2019 Jan 3;38(1). pii: e99576. doi: 10.15252/embj.201899576. Epub 2018 Nov 12
• Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM (2019). The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2019 Feb;95(2):333-349. doi: 10.1016/j.kint.2018.08.037. Epub 2018 Dec 3
• Turpin-Nolan SM, Hammerschmidt P, Chen W, Jais A, Timper K, Awazawa M, Brodesser S, Brüning JC (2019). CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Rep. 2019 Jan 2;26(1):1-10.e7. doi: 10.1016/j.celrep.2018.12.031
• Yu H, Dilbaz S, Coßmann J, Hoang AC, Diedrich V, Herwig A, Harauma A, Hoshi Y, Moriguchi T, Landgraf K, Körner A, Lucas C, Brodesser S, Balogh L, Thuróczy J, Karemore G, Kuefner MS, Park EA, Rapp C, Travers JB, Röszer T (2019). Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages. J Clin Invest. 2019 May 13;130:2485-2499. doi: 10.1172/JCI125646. eCollection 2019 May 13

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Jens Brüning  

• Cheng Y, Luo H, Izzo F, Pickering BF, Nguyen D, Myers R, Schurer A, Gourkanti S, Brüning JC, Vu LP, Jaffrey SR, Landau DA, Kharas MG (2019). m₆A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment. Cell Rep. 2019 Aug 13;28(7):1703-1716.e6. doi: 10.1016/j.celrep.2019.07.032.
• Edwin Thanarajah S, Hoffstall V, Rigoux L, Hanssen R, Brüning JC, Tittgemeyer M (2019). The role of insulin sensitivity and intranasally applied insulin on olfactory perception. Sci Rep. 2019 May 10;9(1):7222. doi: 10.1038/s41598-019-43693-7.
• Edwin Thanarajah S, Iglesias S, Kuzmanovic B, Rigoux L, Stephan KE, Brüning JC, Tittgemeyer M (2019). Modulation of midbrain neurocircuitry by intranasal insulin. Neuroimage. 2019 Jul 1;194:120-127. doi: 10.1016/j.neuroimage.2019.03.050. Epub 2019 Mar 23.  
• Hammerschmidt P, Ostkotte D, Nolte H, Gerl MJ, Jais A, Brunner HL, Sprenger HG, Awazawa M, Nicholls HT, Turpin-Nolan SM, Langer T, Krüger M, Brügger B, Brüning JC (2019). CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity. Cell. 2019 May 30;177(6):1536-1552.e23. doi: 10.1016/j.cell.2019.05.008.
• Ip, C.K., Zhang, L., Farzi, A., Qi, Y., Clarke, I., Reed, F., Shi, Y.C., Enriquez, R., Dayas, C., Graham, B., Begg, D., Brüning, J.C., Lee, N.J., Hernandez-Sanchez, D., Gopalasingam, G., Koller, J., Tasan, R., Sperk, G., and Herzog, H. (2019). Amygdala NPY Circuits Promote the Development of Accelerated Obesity under Chronic Stress Conditions. Cell Metab 30, 111-128 e116. 10.1016/j.cmet.2019.04.001.
• Lippert RN, Cremer AL, Edwin Thanarajah S, Korn C, Jahans-Price T, Burgeno LM, Tittgemeyer M, Brüning JC, Walton ME, Backes H (2019). Time-dependent assessment of stimulus-evoked regional dopamine release. Nat Commun. 2019 Jan 18;10(1):336. doi: 10.1038/s41467-018-08143-4.
• MacVicar T, Ohba Y, Nolte H, Mayer FC, Tatsuta T, Sprenger HG, Lindner B, Zhao Y, Li J, Bruns C, Krüger M, Habich M, Riemer J, Schwarzer R, Pasparakis M, Henschke S, Brüning JC, Zamboni N, Langer T (2019). Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature. 2019 Nov;575(7782):361-365. doi: 10.1038/s41586-019-1738-6. Epub 2019 Nov 6.
• Ostermann AL, Wunderlich CM, Schneiders L, Vogt MC, Woeste MA, Belgardt BF, Niessen CM, Martiny B, Schauss AC, Frommolt P, Nikolaev A, Hövelmeyer N, Sears RC, Koch PJ, Günzel D, Brüning JC, Wunderlich FT (2019). Intestinal insulin/IGF1 signalling through FoxO1 regulates epithelial integrity and susceptibility to colon cancer. Nat Metab. 2019 Mar;1(3):371-389. doi: 10.1038/s42255-019-0037-8. Epub 2019 Mar 4. PMID: 32694718.
• Raichur S, Brunner B, Bielohuby M, Hansen G, Pfenninger A, Wang B, Bruning JC, Larsen PJ, Tennagels N (2019). The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach. Mol Metab. 2019 Mar;21:36-50. doi: 10.1016/j.molmet.2018.12.008. Epub 2019 Jan 2.
• Ruud J, Alber J, Tokarska A, Engström Ruud L, Nolte H, Biglari N, Lippert R, Lautenschlager Ä, Cieślak PE, Szumiec Ł, Hess ME, Brönneke HS, Krüger M, Nissbrandt H, Korotkova T, Silberberg G, Rodriguez Parkitna J, Brüning JC (2019). The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons. Cell Rep. 2019 Jun 11;27(11):3182-3198.e9. doi: 10.1016/j.celrep.2019.05.037.
• Thanarajah SE, Backes H, DiFeliceantonio AG, Albus K, Cremer AL, Hanssen R, Lippert RN, Cornely OA, Small DM, Bruning JC, Tittgemeyer M (2019). Food Intake Recruits Orosensory and Post-ingestive Dopaminergic Circuits to Affect Eating Desire in Humans. Cell Metab. 2019 Mar 5;29(3):695-706.e4. doi: 10.1016/j.cmet.2018.12.006. Epub 2018 Dec 27.
• Turpin-Nolan SM, Hammerschmidt P, Chen W, Jais A, Timper K, Awazawa M, Brodesser S, Brüning JC (2019). CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Rep. 2019 Jan 2;26(1):1-10.e7. doi: 10.1016/j.celrep.2018.12.031.
• Wachsmuth, E., Awazawa, M., Aghdam, S., Akyüz, M., Bloch, W., Brüning, J.C., and Niessen, C.M. (2019). Skin insulin resistance impairs skin barrier function in hyperglycemic and diabetic mouse models. J Invest Dermatol 139, S59-S59.
• Wang L, De Solis AJ, Goffer Y, Birkenbach KE, Engle SE, Tanis R, Levenson JM, Li X, Rausch R, Purohit M, Lee JY, Tan J, De Rosa MC, Doege CA, Aaron HL, Martins GJ, Brüning JC, Egli D, Costa R, Berbari N, Leibel RL, Stratigopoulos G (2019). Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development. JCI Insight. 2019 Feb 7;4(3). pii: 123337. doi: 10.1172/jci.insight.123337. [Epub ahead of print]. 

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Oliver Cornely

• Bacher P, Hohnstein T, Beerbaum E, Rocker M, Blango MG, Kaufmann S, Rohmel J, Eschenhagen P, Grehn C, Seidel K, Rickerts V, Lozza L, Stervbo U, Nienen M, Babel N, Milleck J, Assenmacher M, Cornely OA, Ziegler M, Wisplinghoff H, Heine G, Worm M, Siegmund B, Maul J, Creutz P, Tabeling C, Ruwwe-Glosenkamp C, Sander LE, Knosalla C, Brunke S, Hube B, Kniemeyer O, Brakhage AA, Schwarz C, Scheffold A (2019). Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans. Cell 2019 Mar 7;176(6):1340-1355.e15. doi: 10.1016/j.cell.2019.01.041. Epub 2019 Feb 21.
• Bassetti M, Giacobbe DR, Vena A, Trucchi C, Ansaldi F, Antonelli M, Adamkova V, Alicino C, Almyroudi MP, Atchade E, Azzini AM, Carannante N, Carnelutti A, Corcione S, Cortegiani A, Dimopoulos G, Dubler S, Garcia-Garmendia JL, Girardis M, Cornely OA, Ianniruberto S, Kullberg BJ, Lagrou K, Le Bihan C, Luzzati R, Malbrain M, Merelli M, Marques AJ, Martin-Loeches I, Mesini A, Paiva JA, Peghin M, Raineri SM, Rautemaa-Richardson R, Schouten J, Brugnaro P, Spapen H, Tasioudis P, Timsit JF, Tisa V, Tumbarello M, van den Berg C, Veber B, Venditti M, Voiriot G, Wauters J, Montravers P (2019). Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project. Crit Care. 2019 Jun 14;23(1):219. doi: 10.1186/s13054-019-2497-3.
• Bassetti M, Scudeller L, Giacobbe DR, Lamoth F, Righi E, Zuccaro V, Grecchi C, Rebuffi C, Akova M, Alastruey-Izquierdo A, Arikan-Akdagli S, Azoulay E, Blot SI, Cornely OA, Lass-Flörl C, Koehler P, Cuenca-Estrella M, de Lange DW, De Rosa FG, De Waele JJ, Dimopoulos G, Garnacho-Montero J, Hoenigl M, Kanj SS, Maertens J, Martin-Loeches I, Muñoz P, Kullberg BJ, Agvald-Ohman C, Poulakou G, Rello J, Sanguinetti M, Taccone FS, Timsit JF, Torres A, Vazquez JA, Calandra T (2019). Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project. Mycoses. 2019 Apr;62(4):310-319. doi: 10.1111/myc.12869. Epub 2019 Jan 22
• Boch T, Spiess B, Heinz W, Cornely OA, Schwerdtfeger R, Hahn J, Krause SW, Duerken M, Bertz H, Reuter S, Kiehl M, Claus B, Deckert PM, Hofmann WK, Buchheidt D, Reinwald M (2019). Aspergillus specific nested PCR from the site of infection is superior to testing concurrent blood samples in immunocompromised patients with suspected invasive aspergillosis. Mycoses. 2019 Nov;62(11):1035-1042. doi: 10.1111/myc.12983
• Buchta V, Bolehovska R, Hovorkova E, Cornely OA, Seidel D, Zak P (2019). Saprochaete clavata Invasive Infections - A New Threat to Hematological-Oncological Patients. Front Microbiol. 2019; 10: 2196
• Cheng MP, Lawandi A, Lee TC, Dufresne PJ, Seidel D, Verweij PE, Cornely OA, Sheppard DC (2019). Triazole Antifungal Susceptibility Patterns among Aspergillus Species in Quebec, Canada. J Clin Microbiol. 2019; 57(6)
• Cornely OA, Alastruey-Izquierdo A, Arenz D, Chen SCA, Dannaoui E, Hochhegger B, Hoenigl M, Jensen HE, Lagrou K, Lewis RE, Mellinghoff SC, Mer M, Pana ZD, Seidel D, Sheppard DC, Wahba R, Akova M, Alanio A, Al-Hatmi AMS, Arikan-Akdagli S, Badali H, Ben-Ami R, Bonifaz A, Bretagne S, Castagnola E, Chayakulkeeree M, Colombo AL, Corzo-Leon DE, Drgona L, Groll AH, Guinea J, Heussel CP, Ibrahim AS, Kanj SS, Klimko N, Lackner M, Lamoth F, Lanternier F, Lass-Floerl C, Lee DG, Lehrnbecher T, Lmimouni BE, Mares M, Maschmeyer G, Meis JF, Meletiadis J, Morrissey CO, Nucci M, Oladele R, Pagano L, Pasqualotto A, Patel A, Racil Z, Richardson M, Roilides E, Ruhnke M, Seyedmousavi S, Sidharthan N, Singh N, Sinko J, Skiada A, Slavin M, Soman R, Spellberg B, Steinbach W, Tan BH, Ullmann AJ, Vehreschild JJ, Vehreschild M, Walsh TJ, White PL, Wiederhold NP, Zaoutis T, Chakrabarti A (2019). Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium. Lancet Infect Dis. 2019 Dec;19(12):e405-e421. doi: 10.1016/S1473-3099(19)30312-3. Epub 2019 Nov 5
• Cornely OA, Hoenigl M, Lass-Florl C, Chen SC, Kontoyiannis DP, Morrissey CO, Thompson GR 3rd (2019). Defining breakthrough invasive fungal infection-Position paper of the mycoses study group education and research consortium and the European Confederation of Medical Mycology. Mycoses. 2019 Sep;62(9):716-729. doi: 10.1111/myc.12960. Epub 2019 Jul 19
• Cornely OA, Small DM, Bruning JC, Tittgemeyer M (2019). Food Intake Recruits Orosensory and Post-ingestive Dopaminergic Circuits to Affect Eating Desire in Humans. Cell Metab. 2019 Mar 5;29(3):695-706.e4. doi: 10.1016/j.cmet.2018.12.006. Epub 2018 Dec 27
• Cornely OA, Vehreschild M, Adomakoh N, Georgopali A, Karas A, Kazeem G, Guery B (2019). Extended-pulsed fidaxomicin versus vancomycin for Clostridium difficile infection: EXTEND study subgroup analyses. Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1187-1194. doi: 10.1007/s10096-019-03525-y. Epub 2019 Mar 25
• Farowski F, Solbach P, Tsakmaklis A, Brodesser S, Cruz Aguilar MR, Cornely OA, Dettmer K, Higgins PG, Suerbaum S, Jazmati N, Oefner PJ, Vehreschild M (2019). Potential biomarkers to predict outcome of faecal microbiota transfer for recurrent Clostridioides difficile infection. Dig Liver Dis. 2019 Jul;51(7):944-951. doi: 10.1016/j.dld.2019.01.012. Epub 2019 Jan 26
• Gangneux JP, Lortholary O, Cornely OA, Pagano L (2019). 9th Trends in Medical Mycology Held on 11-14 October 2019, Nice, France, Organized under the Auspices of EORTC-IDG and ECMM. J Fungi (Basel) 2019 Oct 8;5(4). pii: E95. doi: 10.3390/jof5040095
• Gerding DN, Cornely OA, Grill S, Kracker H, Marrast AC, Nord CE, Talbot GH, Buitrago M, Gheorghe Diaconescu I, Murta de Oliveira C, Preotescu L, Pullman J, Louie TJ, Wilcox MH (2019). Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trials. Lancet Infect Dis. 2019 Mar;19(3):265-274. doi: 10.1016/S1473-3099(18)30614-5. Epub 2019 Jan 29
• Hamprecht A, Barber AE, Mellinghoff SC, Thelen P, Walther G, Yu Y, Neurgaonkar P, Dandekar T, Cornely OA, Martin R, Kurzai O (2019). Candida auris in Germany and Previous Exposure to Foreign Healthcare. Emerg Infect Dis. 2019 Sep;25(9):1763-1765. doi: 10.3201/eid2509.190262. Epub 2019 Sep 17
• Heimann SM, Vehreschild M, Cornely OA, Heinz WJ, Grüner B, Silling G, Kessel J, Seidel D, Vehreschild JJ (2019). Healthcare burden of probable and proven invasive mucormycosis: a multi-centre cost-of-illness analysis of patients treated in tertiary care hospitals between 2003 and 2016. J Hosp Infect. 2019 Mar;101(3):339-346. doi: 10.1016/j.jhin.2018.11.003. Epub 2018 Nov 10.
• Koehler P, Arendrup MC, Arikan-Akdagli S, Bassetti M, Bretagne S, Klingspor L, Lagrou K, Meis JF, Rautemaa-Richardson R, Schelenz S, Hamprecht A, Koehler FC, Kurzai O, Salmanton-Garcia J, Vehreschild JJ, Alanio A, Alastruey-Izquierdo A, Arsic Arsenijevic V, Gangneux JP, Gow NAR, Hadina S, Hamal P, Johnson E, Klimko N, Lass-Florl C, Mares M, Ozenci V, Papp T, Roilides E, Sabino R, Segal E, Talento AF, Tortorano AM, Verweij PE, Hoenigl M, Cornely OA (2019). ECMM CandiReg-A ready to use platform for outbreaks and epidemiological studies. Mycoses. 2019 Oct;62(10):920-927. doi: 10.1111/myc.12963. Epub 2019 Aug 1
• Koehler P, Bassetti M, Kochanek M, Shimabukuro-Vornhagen A, Cornely OA (2019). Intensive Care management of influenza-associated pulmonary aspergillosis. Clin Microbiol Infect. 2019 Dec;25(12):1501-1509. doi: 10.1016/j.cmi.2019.04.031. Epub 2019 May 16
• Koehler P, Jung N, Cornely OA, Rybniker J, Fatkenheuer G (2019). Combination Antimicrobial Therapy for Enterococcus faecalis Infective Endocarditis. Clin Infect Dis. 2019 Aug 16;69(5):900. doi: 10.1093/cid/ciz054
• Koehler P, Mellinghoff SC, Lagrou K, Alanio A, Arenz D, Hoenigl M, Koehler FC, Lass-Florl C, Meis JF, Richardson M, Cornely OA (2019). Development and validation of the European QUALity (EQUAL) score for mucormycosis management in haematology. J Antimicrob Chemother. 2019 Jun 1;74(6):1704-1712. doi: 10.1093/jac/dkz051
• Koehler P, Salmanton-Garcia J, Grafe SK, Koehler FC, Mellinghoff SC, Seidel D, Steinbach A, Cornely OA (2019). Baseline predictors influencing the prognosis of invasive aspergillosis in adults. Mycoses. 2019 Aug;62(8):651-658. doi: 10.1111/myc.12926. Epub 2019 May 23
• Koehler P, Stecher M, Cornely OA, Koehler D, Vehreschild M, Bohlius J, Wisplinghoff H, Vehreschild JJ (2019). Morbidity and mortality of candidaemia in Europe: an epidemiologic meta-analysis. Clin Microbiol Infect. 2019 Oct;25(10):1200-1212. doi: 10.1016/j.cmi.2019.04.024. Epub 2019 Apr 27
• Lilienfeld-Toal M von, Wagener J, Einsele H, Cornely OA, Kurzai O (2019). Invasive Fungal Infection. Dtsch Arztebl Int. 2019; 116(16): 271-8
• Maschmeyer G, Ostermann H, Von Lilienfeld-Toal M, Rieger C, Vehreschild M, Cornely OA, Buchheidt D (2019). Pitfalls in der antimikrobiellen Therapie – Hinweise der Arbeitsgemeinschaft Infektionen in der Hämatologie und Onkologie (AGIHO). DGHO Mitgliederrundschreiben 2019; (1/2019)
• Mellinghoff SC, Otto C, Cornely OA (2019). Surgical site infections: current management and role of new antibiotics. Curr Opin Infect Dis. 2019 Oct;32(5):517-522. doi: 10.1097/QCO.0000000000000589
• Mellinghoff SC, Vehreschild JJ, Liss BJ, Cornely OA (2019). Metadata Correction: Epidemiology of Surgical Site Infections With Staphylococcus aureus in Europe: Protocol for a Retrospective, Multicenter Study. JMIR Res Protoc. 2019; 8(1): e10712
• Mellinghoff SC, von Bergwelt-Baildon M, Schosser HA, Cornely OA (2019). A novel approach to candidemia? The potential role of checkpoint inhibition. Med Mycol. 2019 Feb 1;57(2):151-154. doi: 10.1093/mmy/myy089
• Oladele RO, Osaigbovo, II, Ayanlowo OO, Otu AA, Hoenigl M, Cornely OA, Chakrabarti A, Denning DW (2019). The role of medical mycology societies in combating invasive fungal infections in low- and middle-income countries: A Nigerian model. Mycoses 2019 Jan;62(1):16-21. doi: 10.1111/myc.12845. Epub 2018 Oct
• Perez-Hansen A, Lass-Florl C, Lackner M, Aigner M, Alastruey-Izquierdo A, Arikan-Akdagli S, Bader O, Becker K, Boekhout T, Buzina W, Cornely OA, Hamal P, Kidd SE, Kurzai O, Lagrou K, Colombo AL, Mares M, Masoud H, Meis JF, Oliveri S, Rodloff AC, Orth-Holler D, Guerrero-Lozano I, Sanguinetti M, Segal E, Taj-Aldeen SJ, Tortorano AM, Trovato L, Walther G, Willinger B, Rare Yeast Study G (2019). Antifungal susceptibility profiles of rare ascomycetous yeasts. J Antimicrob Chemother. 2019 Sep 1;74(9):2649-2656. doi: 10.1093/jac/dkz231.
• Rammaert B, Puyade M, Cornely OA, Seidel D, Grossi P, Husain S, Picard C, Lass-Florl C, Manuel O, Le Pavec J, Lortholary O (2019). Perspectives on Scedosporium species and Lomentospora prolificans in lung transplantation: Results of an international practice survey from ESCMID fungal infection study group and study group for infections in compromised hosts, and European Confederation of Medical Mycology. Transpl Infect Dis. 2019 Oct;21(5):e13141. doi: 10.1111/tid.13141. Epub 2019 Jul 22
• Salmanton-Garcia J, Seidel D, Koehler P, Mellinghoff SC, Herbrecht R, Klimko N, Racil Z, Falces-Romero I, Ingram P, Benitez-Penuela MA, Rodriguez JY, Desoubeaux G, Barac A, Garcia-Vidal C, Hoenigl M, Mehta SR, Cheng MP, Klyasova G, Heinz WJ, Iqbal N, Krause R, Ostermann H, Penack O, Schalk E, Sheppard DC, Willinger B, Wisplinghoff H, Vehreschild JJ, Cornely OA, Vehreschild M (2019). Matched-paired analysis of patients treated for invasive mucormycosis: standard treatment versus posaconazole new formulations (MoveOn). J Antimicrob Chemother. 2019 Nov 1;74(11):3315-3327. doi: 10.1093/jac/dkz344
• Schommers P, Gruell H, Abernathy ME, Dingens AS, Tran MK, Gristick HB, Barnes CO, Schoofs T, Schlotz M, Vanshylla K, Kreer C, Weiland D, Holtick U, Scheid C, Valter MM, van Gils MJ, Sanders RW, Vehreschild JJ, Cornely OA, Lehmann C, Fatkenheuer G, Seaman MS, Bloom JD, Bjorkman PJ, Klein F (2019). Novel highly potent CD4bs bNAb with restricted pathway to HIV-1 escape. Hiv Medicine. 2019; 20: 50-.
• Schwarz P, Cornely OA, Dannaoui E (2019). Antifungal combinations in Mucorales: a microbiological perspective. Mycoses. 2019 Sep;62(9):746-760. doi: 10.1111/myc.12909. Epub 2019 Jul 19
• Seidel D, Cornely OA, Arenz D, Meis JF, Vehreschild JJ, Salmanton-Garcia J, Zarrouk M, Falces-Romero I, Racil Z, Lagrou K, Maertens J, Sharpe AR, Blennow O, Lass-Florl C, Le Govic Y, Ostojic A, Desoubeaux G, Alakel N, Schalk E, Bergeron A, Steinmann J, Buchheidt D, Stanzani M, Klimko N, Melchers WJG, Vehreschild MJG, Verweij PE (2019). Clinical implications of azole-resistant vs. azole-susceptible invasive aspergillosis in hematological malignancy (CLARITY) - a multicenter study. Open Forum Infect Dis. 2019 Oct; 6(Suppl 2): S776.Published online 2019 Oct 23. doi: 10.1093/ofid/ofz360.1946
• Seidel D, Meissner A, Lackner M, Piepenbrock E, Salmanton-Garcia J, Stecher M, Mellinghoff S, Hamprecht A, Duran Graeff L, Kohler P, Cheng MP, Denis J, Chedotal I, Chander J, Pakstis DL, Los-Arcos I, Slavin M, Montagna MT, Caggiano G, Mares M, Trauth J, Aurbach U, Vehreschild M, Vehreschild JJ, Duarte RF, Herbrecht R, Wisplinghoff H, Cornely OA (2019). Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope((R)). Crit Rev Microbiol.2019 Feb;45(1):1-21. doi: 10.1080/1040841X.2018.1514366. Epub 2019 Jan 10
• Skladny J, Reinwald M, Boch T, Cornely OA, Honigl M, Heinz WJ, Steinmann J, Rath PM, Merker N, Hofmann WK, Buchheidt D, Spiess B (2019). Molecular detection of Aspergillus using AsperGenius (R) PCR analysis combined with galactomannan determination and Mucorales DNA using the MucorGenius (R) PCR system in clinical samples of immunocompromised patients. Mycoses. 2019; 62: 14-5.
• Springer J, Smith IM, Hartmann S, Winkelmann R, Wilmes D, Cornely O, Kessel J, Loffler J, Rickerts V (2019). Identification of Aspergillus and Mucorales in formalin-fixed, paraffin-embedded tissue samples: Comparison of specific and broad-range fungal qPCR assays. Med Mycol. 2019 Apr 1;57(3):308-313. doi: 10.1093/mmy/myy041
• Steinbach A, Cornely OA, Wisplinghoff H, Schauss AC, Vehreschild JJ, Rybniker J, Hamprecht A, Richter A, Bacher P, Scheffold A, Koehler P (2019). Mould-reactive T cells for the diagnosis of invasive mould infection-A prospective study. Mycoses. 2019 Jul;62(7):562-569. doi: 10.1111/myc.12919. Epub 2019 May 23
• Thanarajah SE, Backes H, DiFeliceantonio AG, Albus K, Cremer AL, Hanssen R, Lippert RN, Cornely OA, Small DM, Brüning JC, Tittgemeyer M (2019). Food Intake Recruits Orosensory and Post-ingestive Dopaminergic Circuits to Affect Eating Desire in Humans. Cell Metab. 2019 Mar 5;29(3):695-706.e4. doi: 10.1016/j.cmet.2018.12.006. Epub 2018 Dec 27.
• Wilcox MH, Cornely OA, Guery B, Longshaw C, Georgopali A, Karas A, Kazeem G, Palacios-Fabrega JA, Vehreschild M (2019). Microbiological Characterization and Clinical Outcomes After Extended-Pulsed Fidaxomicin Treatment for Clostridioides difficile Infection in the EXTEND Study. Open Forum Infect Dis.2019 Nov 6;6(11):ofz436. doi: 10.1093/ofid/ofz436. eCollection 2019 Nov

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Joris Deelen

• Deelen, J., Evans, D.S., Arking, D.E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M.K., Biggs, M.L., van der Spek, A., Atzmon, G., Ware, E.B., Sarnowski, C., Smith, A.V., Seppala, I., Cordell, H.J., Dose, J., Amin, N., Arnold, A.M., Ayers, K.L., Barzilai, N., Becker, E.J., Beekman, M., Blanche, H., Christensen, K., Christiansen, L., Collerton, J.C., Cubaynes, S., Cummings, S.R., Davies, K., Debrabant, B., Deleuze, J.F., Duncan, R., Faul, J.D., Franceschi, C., Galan, P., Gudnason, V., Harris, T.B., Huisman, M., Hurme, M.A., Jagger, C., Jansen, I., Jylha, M., Kahonen, M., Karasik, D., Kardia, S.L.R., Kingston, A., Kirkwood, T.B.L., Launer, L.J., Lehtimaki, T., Lieb, W., Lyytikainen, L.P., Martin-Ruiz, C., Min, J., Nebel, A., Newman, A.B., Nie, C., Nohr, E.A., Orwoll, E.S., Perls, T.T., Province, M.A., Psaty, B.M., Raitakari, O.T., Reinders, M.J.T., Robine, J.M., Rotter, J.I., Sebastiani, P., Smith, J., Sorensen, T.I.A., Taylor, K.D., Uitterlinden, A.G., van der Flier, W., van der Lee, S.J., van Duijn, C.M., van Heemst, D., Vaupel, J.W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D.P., Lunetta, K.L., Slagboom, P.E., and Murabito, J.M. (2019). A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun10, 3669. 10.1038/s41467-019-11558-2.
• Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmuller, G., Boyd, A., Zierer, J., van den Akker, E.B., Ala-Korpela, M., Amin, N., Demirkan, A., Ghanbari, M., van Heemst, D., Ikram, M.A., van Klinken, J.B., Mooijaart, S.P., Peters, A., Salomaa, V., Sattar, N., Spector, T.D., Tiemeier, H., Verhoeven, A., Waldenberger, M., Wurtz, P., Davey Smith, G., Metspalu, A., Perola, M., Menni, C., Geleijnse, J.M., Drenos, F., Beekman, M., Jukema, J.W., van Duijn, C.M., and Slagboom, P.E. (2019). A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals. Nat Commun10, 3346. 10.1038/s41467-019-11311-9.

Martin Denzel

• Brown, P., Tan, A.C., El-Esawi, M.A., Liehr, T., Blanck, O., Gladue, D.P., Almeida, G.M.F., Cernava, T., Sorzano, C.O., Yeung, A.W.K., Engel, M.S., Chandrasekaran, A.R., Muth, T., Staege, M.S., Daulatabad, S.V., Widera, D., Zhang, J.P., Meule, A., Honjo, K., Pourret, O., Yin, C.C., Zhang, Z., Cascella, M., Flegel, W.A., Goodyear, C.S., van Raaij, M.J., Bukowy-Bieryllo, Z., Campana, L.G., Kurniawan, N.A., Lalaouna, D., Hüttner, F.J., Ammerman, B.A., Ehret, F., Cobine, P.A., Tan, E.C., Han, H.M., Xia, W.F., McCrum, C., Dings, R.P.M., Marinello, F., Nilsson, H., Nixon, B., Voskarides, K., Yang, L., […] Denzel, M.S., […] Lyu, R., Pullan, W., Zhou, Y.Q., and Consortium, R. (2019). Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database-Oxford. ARTN baz085. 10.1093/database/baz085.
• Denzel, M.S., Lapierre, L.R., and Mack, H.I.D. (2019). Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics. Mech Ageing Dev 177, 4-21. 10.1016/j.mad.2018.08.001.
• Horn M, Metge F, Denzel MS (2019). Unbiased Forward Genetic Screening with Chemical Mutagenesis to Uncover Drug-Target Interactions. Methods Mol Biol. 2019;1953:23-31. doi: 10.1007/978-1-4939-9145-7_2 
• Sawarkar R, Scherz-Shouval R, Denzel MS, Saarikangas J (2019). Chaperoning junior faculty: Institutional support and guidance can relieve challenges for early-career group leaders and improve academic performance. EMBO Rep. 2019 Jan;20(1). pii: e47163. doi: 10.15252/embr.201847163. Epub 2018 Nov 23  

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Sabine Eming

• Calimport, S.R.G., Bentley, B.L., Stewart, C., Pawelec, G., Scuteri, A., Vinciguerra, M., Slack, C., Chen, D., Harries, L.W., Marchant, G., Fleming, G.A., Conboy, M., Antebi, A., Small, G.W., Gil, J., Lakatta, E.G., Richardson, A., Rosen, C., Nikolich, K., Wyss-Coray, T., Steinman, L., Montine, T., de Magalhaes, J.P., Campisi, J., and Church, G. (2019). To help aging populations, classify organismal senescence. Science 366, 576-+. 10.1126/science.aay7319.
• Ding, X., Willenborg, S., Kakanj, P., Leptin, M., and Eming, S. (2019). Metabolic control of epithelial-immune interactions in the skin. J Invest Dermatol 139, S250-S250. DOI 10.1016/j.jid.2019.07.212.
• Hos, D., Kiesewetter, A., Cursiefen, C., and Eming, S.A. (2019). CSFR-1⁺ CX3CR1⁺ resident corneal macrophages regulate inflammatory corneal hemangiogenesis. Invest Ophth Vis Sci 60.
• Knipper JA, Ding X, Eming SA (2019). Diabetes Impedes the Epigenetic Switch of Macrophages into Repair Mode. Immunity. 2019 Aug 20;51(2):199-201. doi: 10.1016/j.immuni.2019.07.009
• Maschke, J., Bühler, B., Helbig, D., von Stebut-Borschitz, E., and Eming, S. (2019). Verrucous Carcinoma in Patients with long-standing Hidradenitis suppurativa/Acne inversa - A High-risk Entity? J Dtsch Dermatol Ges 17, 87-87.
• Naetlitz, J., Boix, J., Weiland, D., Eming, S.A., and Wiesner, R.J. (2019). Mitochondrial DNA depletion leads to impaired proliferation, migration and contractile performance of dermal fibroblasts. Exp Dermatol 28, E15-E16.
• Pamuk, A., Alakus, H., Eming, S., Mauch, C., and Bruns, C. (2019). 5-year Survival in metastatic Melanoma under Treatment with Dabrafenib plus Trametinib. Onkologe 25, 1024-1025. 10.1007/s00761-019-00668-7.
• Rongisch R, Haese S, Eming SA (2019). [38-year-old female with a treatment-resistant ulcer : Preparation for the specialist examination: part 48]. Hautarzt. 2019 Apr;70(Suppl 1):81-84. doi: 10.1007/s00105-019-4364-1  
• Rongisch, R., and Eming, S. (2019). JAK 2-Mutation in Pyoderma gangraenosum as a Harbinger of Hematological Diseases. J Dtsch Dermatol Ges 17, 73-73.
• Schönborn, K., Willenborg, S., Schulz, J., Quondamatteo, F., Eming, S., Niehoff, A., Imhoff, T., Koch, M., Krieg, T., and Eckes, B. (2019). Fibroblast-specific overexpression of collagen XII leads to a delay in skin repair. J Invest Dermatol 139, S322-S322. DOI 10.1016/j.jid.2019.07.630. 

Mafalda Escobar-Henriques

• Anton V, Buntenbroich I, Schuster R, Babatz F, Simões T, Altin S, Calabrese G, Riemer J, Schauss A, Escobar-Henriques M (2019). Plasticity in salt bridge allows fusion-competent ubiquitylation of  mitofusins and Cdc48 recognition. Life Sci Alliance. 2019 Nov 18;2(6). pii: e201900491. doi: 10.26508/lsa.201900491. Print 2019 Dec. PMID: 31740565
• Escobar-Henriques M, Joaquim M (2019). Mitofusins: Disease Gatekeepers and Hubs in Mitochondrial Quality Control by E3 Ligases. Front Physiol. 2019 May 9;10:517. doi: 10.3389/fphys.2019.00517. eCollection 2019 

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Christian Frezza

• Fernandez-Antoran D, Piedrafita G, Murai K, Ong SH, Herms A, Frezza C, Jones PH (2019). Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation. Cell Stem Cell. 2019 Sep 5;25(3):329-341.e6. doi: 10.1016/j.stem.2019.06.011. Epub 2019 Jul 18. PMID: 31327664; PMCID: PMC6739485. 
• Gammage PA, Frezza C (2019). Mitochondrial DNA: the overlooked oncogenome? BMC Biol. 2019 Jul 8;17(1):53. doi: 10.1186/s12915-019-0668-y. PMID: 31286943; PMCID: PMC6615100. 
• Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido GA 2nd, Gorman JH 3rd, Gorman RC, Rabinowitz JD (2019). Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metab. 2019 Sep 3;30(3):594-606.e3. doi: 10.1016/j.cmet.2019.06.002. Epub 2019 Jun 27. PMID: 31257152; PMCID: PMC6726553. 
• Kohlhauer M, Pell VR, Burger N, Spiroski AM, Gruszczyk A, Mulvey JF, Mottahedin A, Costa ASH, Frezza C, Ghaleh B, Murphy MP, Tissier R, Krieg T (2019). Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive. Basic Res Cardiol. 2019 Mar 15;114(3):18. doi: 10.1007/s00395-019-0727-0. Erratum in: Basic Res Cardiol. 2019 Apr 9;114(3):24. PMID: 30877396; PMCID: PMC6420484. 
• Martin JL, Costa ASH, Gruszczyk AV, Beach TE, Allen FM, Prag HA, Hinchy EC, Mahbubani K, Hamed M, Tronci L, Nikitopoulou E, James AM, Krieg T, Robinson AJ, Huang MM, Caldwell ST, Logan A, Pala L, Hartley RC, Frezza C, Saeb-Parsy K, Murphy MP (2019). Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation. Nat Metab. 2019 Sep 30;1:966-974. doi: 10.1038/s42255-019-0115-y. PMID: 32395697; PMCID: PMC7212038.
• Pereira M, Chen TD, Buang N, Olona A, Ko JH, Prendecki M, Costa ASH, Nikitopoulou E, Tronci L, Pusey CD, Cook HT, McAdoo SP, Frezza C, Behmoaras J (2019). Acute Iron Deprivation Reprograms Human Macrophage Metabolism and Reduces Inflammation In Vivo. Cell Rep. 2019 Jul 9;28(2):498-511.e5. doi: 10.1016/j.celrep.2019.06.039. PMID: 31291584; PMCID: PMC6635384. 
• Rached MT, Millership SJ, Pedroni SMA, Choudhury AI, Costa ASH, Hardy DG, Glegola JA, Irvine EE, Selman C, Woodberry MC, Yadav VK, Khadayate S, Vidal-Puig A, Virtue S, Frezza C, Withers DJ (2019). Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity. Mol Metab. 2019 Feb;20:38-50. doi: 10.1016/j.molmet.2018.11.010. Epub 2018 Nov 28. PMID: 30553769; PMCID: PMC6358539.
• Ryan DG, Murphy MP, Frezza C, Prag HA, Chouchani ET, O'Neill LA, Mills EL (2019). Coupling Krebs cycle metabolites to signalling in immunity and cancer. Nat Metab. 2019 Jan;1:16-33. doi: 10.1038/s42255-018-0014-7. PMID: 31032474; PMCID: PMC6485344. 
• Thomas LW, Esposito C, Stephen JM, Costa ASH, Frezza C, Blacker TS, Szabadkai G, Ashcroft M (2019). CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism. Cancer Metab. 2019 Jul 16;7:7. doi: 10.1186/s40170-019-0200-4. PMID: 31346464; PMCID: PMC6632184. 
• Tran M, Latifoltojar A, Neves JB, Papoutsaki MV, Gong F, Comment A, Costa ASH, Glaser M, Tran-Dang MA, El Sheikh S, Piga W, Bainbridge A, Barnes A, Young T, Jeraj H, Awais R, Adeleke S, Holt C, O'Callaghan J, Twyman F, Atkinson D, Frezza C, Årstad E, Gadian D, Emberton M, Punwani S (2019). First-in-human in vivonon-invasive assessment of intra-tumoral metabolic heterogeneity in renal cell carcinoma. BJR Case Rep. 2019 May 2;5(3):20190003. doi: 10.1259/bjrcr.20190003. Epub 2019 Mar 5. PMID: 31428445; PMCID: PMC6699984.
• Yong C, Stewart GD, Frezza C (2019). Immunohistochemistry as a tool for screening rare renal cancers. Ann Transl Med. 2019 Dec;7(Suppl 8):S314. doi: 10.21037/atm.2019.10.18. PMID: 31909051; PMCID: PMC6944496. 
• Yong C, Stewart GD, Frezza C (2019). Oncometabolites in renal cancer. Nat Rev Nephrol. 2020 Mar;16(3):156-172. doi: 10.1038/s41581-019-0210-z. Epub 2019 Oct 21. PMID: 31636445; PMCID: PMC7030949. 

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Lukas P. Frenzel

• Al-Sawaf, O., Herling, C.D., Holtick, U., Scheid, C., Cramer, P., Sasse, S., von Tresckow, B., Tuchscherer, A., Fischer, K., Eichhorst, B., Hallek, M., and Frenzel, L.P. (2019). Venetoclax plus rituximab or obinutuzumab after allogeneic hematopoietic stem cell transplantation in chronic lymphocytic leukemia. Haematologica104, E224-E226. 10.3324/haematol.2018.212837.
• Beckmann, L., Berg, V., Dickhut, C., Krause, G., Zahedi, R., Hallek, M., and Frenzel, L.P. (2019). BIM Regulation Is BTK Dependent and Can be Targeted By Entospletinib in Ibrutinib Refractory Mutants. Blood134. 10.1182/blood-2019-127148.
• Pelzer, B., Brezkojakova, H., Archodoulakis, A., Unzu, T., Said, S., Guescui, S., Esencan, D., Vlandos, S., Aquilina, E., Kocabas, D., Saydam, S., Özdemir, E., Tundrev, H., Eres, D., Ülker, B., Ispas, C., and Frenzel, L. (2019). Patients with hematological malignancies suffering from hepatitis E infections - a systematic review of case reports and observational studies. Oncol Res Treat42, 260-260.
• Weiss, J., Peifer, M., Herling, C.D., Frenzel, L.P., and Hallek, M. (2019). Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia (Comment to Tausch et al.). Haematologica104, E540-E540. 10.3324/haematol.2019.232835.

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Ana J. Garcia-Saez  

• Danial JSH, Garcia-Saez AJ (2019). Quantitative analysis of super-resolved structures using ASAP. Nat Methods. 2019 Aug;16(8):711-714. doi: 10.1038/s41592-019-0472-1. PMID: 31263253
• Dimou E, Cosentino K, Platonova E, Ros U, Sadeghi M, Kashyap P, Katsinelos T, Wegehingel S, Noé F, García-Sáez AJ, Ewers H, Nickel W (2019). Single event visualization of unconventional secretion of FGF2. J Cell Biol. 2019 Feb 4;218(2):683-699. doi: 10.1083/jcb.201802008. PMID: 30470711
• Flores-Romero H, García-Sáez AJ (2019). MAVS-induced mitochondrial membrane remodeling. FEBS J. 2019 Apr;286(8):1540-1542. doi: 10.1111/febs.14822. PMID: 30957952
• Flores-Romero H, García-Sáez AJ (2019). The Incomplete Puzzle of the BCL2 Proteins. Cells. 2019 Sep 29;8(10). pii: E1176. doi: 10.3390/cells8101176. PMID: 31569576 
• Flores-Romero H, Landeta O, Ugarte-Uribe B, Cosentino K, García-Porras M, García-Sáez AJ, Basañez G (2019). BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL. Cell Death Differ. 2019 Oct;26(10):1880-1894. doi: 10.1038/s41418-018-0258-5. PMID: 30560933
• Flores-Romero, H., Hertlei, V., Das, K.K., Fischer, S., Heunemann, M., Harter, K., and García-Sáez, A.J.(2019). Novel BRET-based proximity biosensor for the study mitochondria-ER contact sites. Cell Death Discovery 5.
• Flores-Romero, H., Hertlein, V., Dash, K.K., Fischer, S., Heunemann, M., Harter, K., and García-Sáez, A.J.(2019). nMERLIN: novel Mitochondria-ER Length Indicative Nanosensor based on BRET. Eur Biophys J Biophy 48, S106-S106.
• García-Sáez, A. (2019). Membrane Permeabilization in Cell Death Signaling. A Single Molecule Approach. Biophys J116, 297a-297a. DOI 10.1016/j.bpj.2018.11.1610.
• Murad F, Garcia-Saez AJ (2019). Quantification of the Interactions Between BCL-2 Proteins by Fluorescence Correlation Spectroscopy. Methods Mol Biol. 2019;1877:337-350. doi: 10.1007/978-1-4939-8861-7_20. PMID: 30536014
• Singh PK, Roukounakis A, Weber A, Das KK, Sohm B, Villunger A, Garcia-Saez AJ, Häcker G (2019). Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim. Cell Death Differ. 2019 Jun 12. doi: 10.1038/s41418-019-0365-y. PMID: 31189926
• Teucher M, Zhang H, Bader V, Winklhofer KF, García-Sáez AJ, Rajca A, Bleicken S, Bordignon E (2019). A new perspective on membrane-embedded Bax oligomers using DEER and bioresistant orthogonal spin labels. Sci Rep. 2019 Sep 10;9(1):13013. doi: 10.1038/s41598-019-49370-z. PMID: 31506457
• Unsay JD, García-Sáez AJ (2019). AFM to Study Pore-Forming Proteins. Methods Mol Biol. 2019;1886:191-202. doi: 10.1007/978-1-4939-8894-5_10. PMID: 30374868

Martin Graef

• Cui R, Medeiros T, Willemsen D, Isai LNM, Collier GE, Graef M, Reichard M, Valenzano DR (2019). Relaxed selection limits lifespan by increasing mutation load. Cell. 2019 Jul 11;178(2):385-399.e20. doi: 10.1016/j.cell.2019.06.004. Epub 2019 Jun 27
• Gabel-Pfisterer, A., Böhringer, D., Agostini, H., Fuest, M., Walter, P., Botros, Y., Mueller, A., Al-Ashi, N., Lenglinger, M., Müller, B., Schönfeld, S., Seibel, I., Joussen, A., Breuss, H., Kuchenbecker, J., Foerster, M.H., Berthold, A., Wirbelauer, C., Hofmayer, H., Wachtlin, J., Palka, K., Niemeyer, M., Walla, T., Pham, D., Aisenbrey, S., Tatsiou, A., Walch, A., Burk, R., Schultz, T., Tsiampalis, N., Rehmann, J., Sliwowska, U., Schojai, M., Schulze, K., Kamguia, N., Wirtz, C., Dick, B., Voelker, D., Wintergerst, M., Pfau, M., Melzer, C., Hoegen, D., Bosch, F., Andresen, J.C., Krohne, T., Holz, F., Kathke, M., Sturm, A., Noske, W., Hübner, T., Brandner, S., Feldmann, M., Morsek, J., Rainer, O., Bartsch, H., Ewald, K., Chankiewitz, E., Siegmund, T., Bohlen, A., Mohr, A., Hecker, J., Strassburger, P., Furashova, O., Engelmann, K., Krieb, A., Emmerich, K., Grajewski, L., Krause, L., Jabur, A., Rüdiger, K., Lehmann, F., Sachs, H., Matthee, E., Steindorf, F., Schnitzler, C., Neumann, I., Korbmacher, J., Geerling, G., Doulgkeridis, J., Erhard, J., Dahms-Dowidat, K., Kotiasvili, T., Jagow, B.V., Lieder, A., Blum, M., Westerkemper, H., Böhm, M., Bornfeld, N., Bechrakis, N., Schultheiss, M., Scheider, A., Müller, M., Kohnen, T., Eckert, T., Eckardt, C., Wisniewska, M., Just, A., Jehle, V., Reinhard, T., Seewald, J., Mais, C., Basiakos, S., Osman, B., Xanthopoulou, E., Friedburg, B., Graef, M., Lorenz, B., Just, U., Naxer, S., Oterendorp, C., Bemme, S., Callizo, J., Feltgen, N., Hoerauf, H., Menges, A., Tost, F., Stahl, A., Huth, A., Viestenz, A., Bertram, P., Skevas, C., Kromer, R., Casagrande, M., Grohmann, C., Mehlan, J., Schindler, P., Spitzer, M., Schargus, M., Eddy, M., Schumacher, S., Keserü, M., Scheler, A., Stemplewitz, B., Schaudig, U., Abou Moulig, W., Framme, C., Rosenthal, A., Hesse, L., Kunz, L., Spira, C., Suffo, S., Seitz, B., Wietstock, G., Augsten, R., Meller, D., Mayer, M., Vanselow, K., Lieb, W., Beutner, A., Effert, R., Ehlken, C., Roider, J., Hueber, A., Cursiefen, K., Schrage, N., Kroeger, M., Viehweg, N., Meier, P., Unterlauft, J.D., Wiedemann, P., Hattenbach, L., Kakkassery, V., Ranjbar, M., Mohi, A., Grisanti, S., Bastron, I., Sarac, S., Kaskel-Paul, S., Stoffelns, B., Schuster, A., Pfeiffer, N., Schulze, S., Praskevas, A., Sekundo, W., Weigel, M., Thieme, H., Wolf, A., Vounotrypidis, E., Priglinger, S., Bechstein, L., Maier, M., Lohmann, C., Haritoglu, C., Alten, F., Eter, N., Klishko, V., Holland, U., Medra, A., Weber, A., Höh, H., Schmidbauer, J., RiveraGomez, C., Plantzas, K., Weiss, M., Hille, K., Höhn, F., Aisenbrey, S., Schrader, M., Napholz, A., Tandogan, T., Walter, C., Zühlsdorff-Uthke, M., Liekfeld, A., Blecha, C., Barth, T., Helbig, H., Juenemann, A., Decker, A., Kühn, M., Ladewig, M., Lenhard, K., Lackner, B., Gekeler, F., Holzschuh, I., Boden, K.T., Szurmann, P., Faul, D., May-Endres, K., Press, U., Luttke, J., Ziemssen, F., Bartz-Schmidt, U., Cordes, J., Raber, F., Mikielewicz, M., Kammerer, J., Kupferschmid, S., Buchwald, H., Raber, F., Werner, J., Kampmeier, J., Bula, A., Krauss, P., Strzalkowski, P., Hillenkamp, J., and Feuerwerks-Verletzungen-Studieng (2019). 3-year results of the German nationwide survey on eye injuries caused by fireworks. Ophthalmologe 116, 1138-1151. 10.1007/s00347-019-00967-9.
• Medeiros TC, Graef M (2019). Autophagy determines mtDNA copy number dynamics during starvation. Autophagy. 2019 Jan;15(1):178-179. doi: 10.1080/15548627.2018.1532263. Epub 2018 Oct 13  

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Michael Hallek

• Al-Sawaf, O., Bazeos, A., Robrecht, S., Bahlo, J., Gower, C., Fink, A.M., Tresckow, J., Cramer, P., Langerbeins, P., Kutsch, N., Humphrey, K., Fingerle-Rowson, G., Stilgenbauer, S., Wendtner, C.M., Fischer, K., Eichhorst, B., Hallek, M., and Goede, V. (2019). Mode of progression after first line treatment correlates with outcome of chronic lymphocytic leukemia (CLL). Am J Hematol 94, 1002-1006. 10.1002/ajh.25561.
• Al-Sawaf, O., Fink, A.M., Robrecht, S., Sinha, A., Tandon, M., Eichhorst, B.F., Fischer, K., and Hallek, M.(2019). Prevention and Management of Tumor Lysis Syndrome in Patients with CLL and Coexisting Conditions Treated with Venetoclax-Obinutuzumab or Chlorambucil-Obinutuzumab: Results from the Randomized CLL14 Trial. Blood 134. 10.1182/blood-2019-126570.
• Al-Sawaf, O., Gentile, B., Devine, J., Sail, K., Tandon, M., Fink, A.M., Kutsch, N., Eichhorst, B.F., Fischer, K., and Hallek, M. (2019). Rapid Improvement of Patient-Reported Outcomes with Venetoclax Plus Obinutuzumab in Patients with Previously Untreated CLL and Coexisting Conditions: A Prospective Analysis from the CLL14 Trial. Blood 134. 10.1182/blood-2019-126542.
• Al-Sawaf, O., Herling, C.D., Holtick, U., Scheid, C., Cramer, P., Sasse, S., von Tresckow, B., Tuchscherer, A., Fischer, K., Eichhorst, B., Hallek, M., and Frenzel, L.P. (2019). Venetoclax plus rituximab or obinutuzumab after allogeneic hematopoietic stem cell transplantation in chronic lymphocytic leukemia. Haematologica 104, E224-E226. 10.3324/haematol.2018.212837.
• Asemissen, A.M., Seibert, J., Haase, S., Oelrich, J., Kreuzer, K.A., Hallek, M., Bokemeyer, C., Giagounidis, A., and Weihrauch, M. (2019). A digital microscopy teaching module for myelodysplastic syndromes - a pilot project for a high quality, innovative and interactive tool for training hematologists. Oncol Res Treat 42, 184-184.
• Bachurski, D., Schuldner, M., Nguyen, P.H., Malz, A., Reiners, K.S., Grenzi, P.C., Babatz, F., Schauss, A.C., Hansen, H.P., Hallek, M., and von Strandmann, E.P. (2019). Extracellular vesicle measurements with nanoparticle tracking analysis - An accuracy and repeatability comparison between NanoSight NS300 and ZetaView. Journal of Extracellular Vesicles 8. Artn 1596016. 10.1080/20013078.2019.1596016.
• Baltin, C., Kron, F., Urbanski, A., Zander, T., Kron, A., Berlth, F., Kleinert, R., Hallek, M., Hoelscher, A.H., and Chon, S.H. (2019). The economic burden of endoscopic treatment for anastomotic leaks following oncological Ivor Lewis esophagectomy. Plos One 14. ARTN e0221406. 10.1371/journal.pone.0221406.
• Barbarino, V., Henschke, S., Blakemore, S.J., Nickel, N., Vorholt, D., Hallek, M., and Pallasch, C. (2019). Functional role of Bruton′s tyrosine kinase inhibitor therapy in the tumor microenvironment of B-cell malignancies. Oncol Res Treat 42, 220-221.
• Beckmann, L., Berg, V., Dickhut, C., Krause, G., Zahedi, R., Hallek, M., and Frenzel, L.P. (2019). BIM Regulation Is BTK Dependent and Can be Targeted By Entospletinib in Ibrutinib Refractory Mutants. Blood 134. 10.1182/blood-2019-127148.
• Beielstein, A., Izquierdo-Alvarez, E., Nickel, N., Vorholt, D., Möllenkötte, I., Hallek, M., and Pallasch, C. (2019). Modulation of antibody-dependent phagocytosis by macrophages under metabolic regulation in the tumor microenvironment. Oncol Res Treat 42, 116-116.
• Blakemore, S.J., Kohlhaas, V., Al-Maarri, M., Knittel, G., Reinhardt, C., Hallek, M., Peifer, M., Wunderlich, T., and Pallasch, C. (2019). Pan-omics assessment of constitutive AKT-activation in the Eμ-TCL1 CLL-like mouse model. Oncol Res Treat 42, 18-18.
• Bokemeyer, C., Hallek, M., Lüftner, D., and Weissinger, F. (2019). Foreword. Oncol Res Treat 42, 1-1. 10.1159/000501222.
• Bühl, L., Abel, T., Wolf, F., Oberste, M., Bloch, W., Hallek, M., Elter, T., and Zimmer, P. (2019). Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia: A Case Report. Integr Cancer Ther 18. Artn 1534735419832358. 10.1177/1534735419832358.
• Chmielewski, M., Kuehle, J., Chrobok, D., Riet, N., Hallek, M., and Abken, H. (2019). FimH-based display of functional eukaryotic proteins on bacteria surfaces. Sci Rep-Uk 9. ARTN 8410. 10.1038/s41598-019-44883-z.
• Davids, M.S., Chatterjee, A., Ravelo, A., Shapouri, S., Manzoor, B.S., Sail, K., Van de Wetering, G., and Hallek, M.(2019). Cost-Effectiveness of a 12-Month Fixed Duration of Venetoclax in Combination with Obinutuzumab in First-Line Chronic Lymphocytic Leukemia in the United States. Blood 134. 10.1182/blood-2019-123706.
• De Silva, N., Robrecht, S., Zhang, C., Cramer, P., Fink, A.M., Fischer, K., Goede, V., Herling, C.D., Hoechstetter, M., Wendtner, C.M., Hallek, M., and Eichhorst, B.F. (2019). Analysis of Outcomes of Younger (≤ 55 Years) Compared with Older (> 55 Years) Patients with Chronic Lymphocytic Leukaemia (CLL) in Seven Studies Conducted By the German CLL Study Group (GCLLSG). Blood 134. 10.1182/blood-2019-126528.
• Drössler, L., Lehmann, C., Töpelt, K., Nierhoff, D., Vehreschild, J.J., Rybniker, J., Hallek, M., Fischer, J., Stormberg, V., Fätkenheuer, G., Wieland, U., and Jung, N. (2019). HBsAg-negative/anti-HBc-positive patients treated with rituximab: prophylaxis or monitoring to prevent hepatitis B reactivation? Infection 47, 293-300. 10.1007/s15010-019-01271-z.
• Eichenauer, D.A., Golla, H., Thielen, I., Hallek, M., Voltz, R., and Perrar, K.M. (2019). Characteristics and course of patients with advanced hematologic malignancies receiving specialized inpatient palliative care at a German university hospital. Ann Hematol 98, 2605-2607. 10.1007/s00277-019-03748-1.
• Eichhorst, B., Fürstenau, M., and Hallek, M. (2019). Relapsed disease and aspects of undetectable MRD and treatment discontinuation. Hematol-Am Soc Hemat, 482-489.
• Fink, A.M., Zhang, C., Robrecht, S., Kutsch, N., Fürstenau, M., Wendtner, C.M., Kreuzer, K.A., Kneba, M., Tausch, E., Stilgenbauer, S., Ritgen, M., Böttcher, S., Fischer, K., Hallek, M., and Eichhorst, B.F. (2019). Comparison of Overall Survival in High Risk Patients with Minimal Residual Disease after First-Line Treatment across Three Generations of Phase 3 Trials of the German CLL Study Group. Blood 134. 10.1182/blood-2019-125063.
• Fischer, K., Al-Sawaf, O., Bahlo, J., Fink, A.M., Tandon, M., Dixon, M., Robrecht, S., Humphrey, K., Böttcher, S., Tausch, E., Humerickhouse, R., Eichhorst, B., Wendtner, C.M., Langerak, A.W., Kreuzer, K.A., Goede, V., Stilgenbauer, S., Mobasher, M., Ritgen, M., and Hallek, M.J. (2019). Effect of fixed-duration venetoclax plus obinutuzumab (VenG) on progression-free survival (PFS), and rates and duration of minimal residual disease negativity (MRD-) in previously untreated patients (pts) with chronic lymphocytic leukemia (CLL) and comorbidities. J Clin Oncol 37.
• Fischer, K., Al-Sawaf, O., Bahlo, J., Fink, A.M., Tandon, M., Dixon, M., Robrecht, S., Warburton, S., Humphrey, K., Samoylova, O., Liberati, A.M., Pinilla-Ibarz, J., Opat, S., Sivcheva, L., Dû, K.L., Fogliatto, L.M., Niemann, C.U., Weinkove, R., Robinson, S., Kipps, T.J., Boettcher, S., Tausch, E., Humerickhouse, R., Eichhorst, B., Wendtner, C.M., Langerak, A.W., Kreuzer, K.A., Ritgen, M., Goede, V., Stilgenbauer, S., Mobasher, M., and Hallek, M. (2019). Venetoclax and Obinutuzumab in Patients with CLL and Coexisting Conditions. New Engl J Med 380, 2225-2236. 10.1056/NEJMoa1815281.
• Fischer, K., Ritgen, M., Al-Sawaf, O., Robrecht, S., Tandon, M., Fink, A.M., Schilhabel, A., Stübig, T., Brüggemann, M., Jiang, Y.W., Schary, W., Eichhorst, B.F., Wendtner, C.M., Tausch, E., Kreuzer, K.A., Langerak, A.W., Goede, V., Böttcher, S., Stilgenbauer, S., Kneba, M., and Hallek, M. (2019). Quantitative Analysis of Minimal Residual Disease (MRD) Shows High Rates of Undetectable MRD after Fixed-Duration Chemotherapy-Free Treatment and Serves As Surrogate Marker for Progression-Free Survival: A Prospective Analysis of the Randomized CLL14 Trial. Blood134. 10.1182/blood-2019-125825.
• Fraser, G., Cramer, P., Demirkan, F., Silva, R.S., Grosicki, S., Pristupa, A., Janssens, A., Mayer, J., Bartlett, N.L., Dilhuydy, M.S., Pylypenko, H., Loscertales, J., Avigdor, A., Rule, S., Villa, D., Samoilova, O., Panagiotidis, P., Goy, A., Pavlovsky, M.A., Karlsson, C., Hallek, M., Mahler, M., Salman, M., Sun, S., Phelps, C., Balasubramanian, S., Howes, A., and Chanan-Khan, A. (2019). Updated results from the phase 3 HELIOS study of ibrutinib, bendamustine, and rituximab in relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma. Leukemia 33, 969-980. 10.1038/s41375-018-0276-9.
• Fürstenau, M., De Silva, N., Eichhorst, B., and Hallek, M.J. (2019). Minimal Residual Disease Assessment in CLL: Ready for Use in Clinical Routine? Hemasphere 3. ARTN e287. 10.1097/HS9.0000000000000287.
• Fürstenau, M., Hallek, M., and Eichhorst, B. (2019). Sequential and combination treatments with novel agents in chronic lymphocytic leukemia. Haematologica 104, 2144-2154. 10.3324/haematol.2018.208603.
• Fürstenau, M., Stumpf, T., Fink, A.M., Robrecht, S., Bahlo, J., Maurer, C., Linde, H., Jacobasch, L., Dörfel, S., Lipke, J., Aldaoud, A., Fischer, K., Eichhorst, B., and Hallek, M. (2019). Second primary malignancies (SPM) in treated and untreated patients with chronic lymphocytic leukemia (CLL): an analysis of the registry of the German CLL Study Group (GCLLSG). Oncol Res Treat 42, 19-19.
• Gärtner, J., Daun, M., Wolf, J., von Bergwelt-Baildon, M., and Hallek, M. (2019). Early Palliative Care: Pro, but Please Be Precise! Oncol Res Treat 42, 11-18. 10.1159/000496184.
• Hallek, M. (2019). Chronic lymphocytic leukemia: 2020 update on diagnosis, risk stratification and treatment. Am J Hematol 94, 1266-1287. 10.1002/ajh.25595.
• Hallek, M., and Fürstenau, M. (2019). How to approach CLL in clinical practice. Hematological Oncology 37, 38-42. 10.1002/hon.2583.
• Hallek, M., and Haller, H. (2019). Multiple Myeloma. Internist 60, 1-2. 10.1007/s00108-018-0553-8.
• Herling, C.D., Coombes, K.R., Benner, A., Bloehdorn, J., Barron, L.L., Abrams, Z.B., Majewski, T., Bondaruk, J.E., Bahlo, J., Fischer, K., Hallek, M., Stilgenbauer, S., Czerniak, B.A., Oakes, C.C., Ferrajoli, A., Keating, M.J., and Abruzzo, L.V. (2019). Time-to-progression after front-line fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy for chronic lymphocytic leukaemia: a retrospective, multicohort study. Lancet Oncol 20, 1576-1586. 10.1016/S1470-2045(19)30503-0.
• Izquierdo-Alvarez, E., Vorholt, D., Wiederstein, J., Lobastova, L., Blakemore, S.J., Krüger, M., Hansen, H., Bruns, H., Hallek, M., and Pallasch, C. (2019). Loss of TP53 modifies the quantity and protein load of extracellular vesicles in leukemic B-cells and influences functional crosstalk within the tumor microenvironment. Oncol Res Treat 42, 66-66.
• Jebaraj, B.M.C., Tausch, E., Landau, D.A., Bahlo, J., Robrecht, S., Taylor-Weiner, A.N., Bloehdorn, J., Scheffold, A., Mertens, D., Böttcher, S., Kneba, M., Jäger, U., Zenz, T., Wenger, M.K., Fingerle-Rowson, G., Wendtner, C., Fink, A.M., Wu, C.J., Eichhorst, B., Fischer, K., Hallek, M., Döhner, H., and Stilgenbauer, S. (2019). Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia. Leukemia 33, 2183-2194. 10.1038/s41375-019-0446-4.
• Kipps, T.J., Fraser, G., Coutre, S.E., Brown, J.R., Barrientos, J.C., Barr, P.M., Byrd, J.C., O'Brien, S.M., Dilhuydy, M.S., Hillmen, P., Jaeger, U., Moreno, C., Cramer, P., Stilgenbauer, S., Chanan-Khan, A.A., Mahler, M., Salman, M., Eckert, K., Solman, I.G., Balasubramanian, S., Cheng, M., Londhe, A., Ninomoto, J., Howes, A., James, D.F., and Hallek, M. (2019). Long-Term Studies Assessing Outcomes of Ibrutinib Therapy in Patients With Del(11q) Chronic Lymphocytic Leukemia. Cl Lymph Myelom Leuk 19, 715-+. 10.1016/j.clml.2019.07.004.
• Kurtz, D.M., Esfahani, M.S., Scherer, F., Soo, J., Jin, M.C., Liu, C.L., Newman, A.M., Dührsen, U., Hüttmann, A., Casasnovas, O., Westin, J.R., Ritgen, M., Böttcher, S., Langerak, A.W., Roschewski, M., Wilson, W.H., Gaidano, G., Rossi, D., Bahlo, J., Hallek, M., Tibshirani, R., Diehn, M., and Alizadeh, A.A. (2019). Dynamic Risk Profiling Using Serial Tumor Biomarkers for Personalized Outcome Prediction. Cell 178, 699-+. 10.1016/j.cell.2019.06.011.
• Kutsch, N., Pallasch, C., Tausch, E., Boehme, V., Ritgen, M., Liersch, R., Wacker, A., Jacobs, G., Trappe, R.U., Dreger, P., Stilgenbauer, S., Zhang, D., Jürgensmeier, J.M., Bhargava, P., Hallek, M., and Eichhorst, B.F. (2019). A Prospective, Open-Label, Multicenter, Phase 2 Trial to Evaluate the Safety and Efficacy of the Combination of Tirabrutinib (ONO/GS-4059) and Entospletinib with and without Obinutuzumab in Patients with Relapsed/ Refractory Chronic Lymphocytic Leukemia (CLL). Blood 134. 10.1182/blood-2019-130912.
• Labouvie, H., Hellmich, S., Fath, B., Hallek, M., and Kusch, M. (2019). Psycho-oncological healthcare needs of patients with non-Hodgkin's lymphoma. Onkologe 25, 914-918. 10.1007/s00761-019-00651-2.
• Langerak, A.W., Ritgen, M., Goede, V., Robrecht, S., Bahlo, J., Fischer, K., Steurer, M., Trneny, M., Mulligan, S.P., Mey, U.J.M., Trunzer, K., Fingerle-Rowson, G., Humphrey, K., Stilgenbauer, S., Böttcher, S., Brüggemann, M., Hallek, M., Kneba, M., and van Dongen, J.J.M. (2019). Prognostic value of MRD in CLL patients with comorbidities receiving chlorambucil plus obinutuzumab or rituximab. Blood 133, 494-497. 10.1182/blood-2018-03-839688.
• Langerbeins, P., Bahlo, J., Rhein, C., Gerwin, H., Cramer, P., Fürstenau, M., Al-Sawaf, O., von Tresckow, J., Fink, A.M., Kreuzer, K.A., Vehling-Kaiser, U., Tausch, E., Müller, L., Eckart, M.J., Schlag, R., Freier, W., Gaska, T., Balser, C., Reiser, M., Stauch, M., Wendtner, C.M., Fischer, K., Stilgenbauer, S., Eichhorst, B., Hallek, M., and Studiengrp, D.C. (2019). Ibrutinib versus placebo in patients with asymptomatic, treatment-naive early stage chronic lymphocytic leukemia (CLL): primary endpoint results of the phase 3 double-blind, placebo-controlled randomized CLL12 trial. Oncol Res Treat 42, 17-17.
• Langerbeins, P., Eichhorst, B., and Hallek, M. (2019). Current treatment strategies for chronic lymphocytic leukemia. Onkologe 25, 1004-1008. 10.1007/s00761-019-00655-y.
• Michels, S., Wolf, J., and Hallek, M. (2019). New concepts for approval of drugs in oncology beyond randomized clinical studies. Onkologe 25, 83-89. 10.1007/s00761-019-0598-x.
• Nguyen, P.H., Niesen, E., and Hallek, M. (2019). New roles for B cell receptor associated kinases: when the B cell is not the target. Leukemia 33, 576-587. 10.1038/s41375-018-0366-8.
• Pflug, N., Cramer, P., Robrecht, S., Bahlo, J., Westermann, A., Fink, A.M., Schrader, A., Mayer, P., Oberbeck, S., Seiler, T., Zenz, T., Dürig, J., Kreuzer, K.A., Stilgenbauer, S., Eichhorst, B., Hallek, M., Herling, M., and Hopfinger, G. (2019). New lessons learned in T-PLL: results from a prospective phase-II trial with fludarabine-mitoxantrone-cyclophosphamide-alemtuzumab induction followed by alemtuzumab maintenance. Leukemia Lymphoma 60, 649-657. 10.1080/10428194.2018.1488253.
• Ram, R., Scheid, C., Amit, O., Chemnitz, J.M., Moshe, Y., Hallek, M., Wolf, D., Avivi, I., and Holtick, U. (2019). Sequential therapy or patients with primary refractory acute myeloid leukemia: a historical prospective analysis of the German and Israeli experience. Haematologica 104, 1798-1803. 10.3324/haematol.2018.203869.
• Rice, C., Eikema, D.J., Marsh, J.C.W., Knol, C., Hebert, K., Putter, H., Peterson, E., Deeg, H.J., Halkes, S., Pidala, J., Anderlini, P., Tischer, J., Kroger, N., McDonald, A., Antin, J.H., Schaap, N.P., Hallek, M., Einsele, H., Mathews, V., Kapoor, N., Boelens, J.J., Mufti, G.J., Potter, V., de la Tour, R.P., Eapen, M., and Dufour, C. (2019). Allogeneic Hematopoietic Cell Transplantation in Patients Aged 50 Years or Older with Severe Aplastic Anemia. Biol Blood Marrow Tr 25, 488-495. 10.1016/j.bbmt.2018.08.029.
• Roberts, A.W., Ma, S., Kipps, T.J., Coutre, S.E., Davids, M.S., Eichhorst, B., Hallek, M., Byrd, J.C., Humphrey, K., Zhou, L., Chyla, B., Nielsen, J., Potluri, J., Kim, S.Y., Verdugo, M., Stilgenbauer, S., Wierda, W.G., and Seymour, J.F. (2019). Efficacy of venetoclax in relapsed chronic lymphocytic leukemia is influenced by disease and response variables. Blood 134, 111-122. 10.1182/blood.2018882555.
• Rossi, A., Dupaty, L., Aillot, L., Zhang, L., Gallien, C., Hallek, M., Odenthal, M., Adriouch, S., Salvetti, A., and Büning, H. (2019). Vector uncoating limits adenoassociated viral vector-mediated transduction of human dendritic cells and vector immunogenicity. Sci Rep-Uk 9. ARTN 3631. 10.1038/s41598-019-40071-1.
• Sachanas, S., Pangalis, G.A., Fink, A.M., Bahlo, J., Fischer, K., Levidou, G., Kyrtsonis, M.C., Bartzi, V., Vassilakopoulos, T.P., Kalpadakis, C., Koulieris, E., Moschogiannis, M., Yiakoumis, X., Tsirkinidis, P., Angelopoulou, M.K., Eichhorst, B., and Hallek, M. (2019). Small Lymphocytic Lymphoma: Analysis of Two Cohorts Including Patients in Clinical Trials of the German Chronic Lymphocytic Leukemia Study Group (GCLLSG) or in "Real-Life" Outside of Clinical Trials. Anticancer Res 39, 2591-2598. 10.21873/anticanres.13382.
• Schuldner, M., Dörsam, B., Shatnyeva, O., Reiners, K.S., Kubarenko, A., Hansen, H.P., Finkernagel, F., Roth, K., Theurich, S., Nist, A., Stiewe, T., Paschen, A., Knittel, G., Reinhardt, H.C., Müller, R., Hallek, M., and von Strandmann, E.P. (2019). Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53. Theranostics 9, 6047-6062. 10.7150/thno.36378.
• Sharman, J.P., Coutre, S.E., Furman, R.R., Cheson, B.D., Pagel, J.M., Hillmen, P., Barrientos, J.C., Zelenetz, A.D., Kipps, T.J., Flinn, I.W., Ghia, P., Eradat, H., Ervin, T., Lamanna, N., Coiffier, B., Pettitt, A.R., Ma, S., Tausch, E., Cramer, P., Huang, J., Mitra, S., Hallek, M., O'Brien, S.M., and Stilgenbauer, S. (2019). Final Results of a Randomized, Phase III Study of Rituximab With or Without Idelalisib Followed by Open-Label Idelalisib in Patients With Relapsed Chronic Lymphocytic Leukemia. J Clin Oncol 37, 1391-+. 10.1200/Jco.18.01460.
• Soumerai, J.D., Ni, A., Xing, G., Huang, J., Furman, R.R., Jones, J., Sharman, J.P., Hallek, M., Adewoye, A.H., Dubowy, R., Dreiling, L., and Zelenetz, A.D. (2019). Evaluation of the CLL-IPI in relapsed and refractory chronic lymphocytic leukemia in idelalisib phase-3 trials. Leukemia Lymphoma 60, 1438-1446. 10.1080/10428194.2018.1540782.
• Stein, A.F.V., Koch, M., Reinarzt, S., Lucas, A., Rebollido-Rios, R., Oellerich, T., Nguyen, P.H., and Hallek, M.(2019). Lyn Kinase Contributes to the Reprogramming of Fibroblasts Promoting Chronic Lymphocytic Leukemia Progression. Blood 134. 10.1182/blood-2019-129299.
• Voltz, R., Hallek, M., Fink, G., Schneider, W., and Heller, A. (2019). Palliative Medicine within the Framework of the Universities: Assessing the Current Position. Z Palliatmedizin 20, 58-60.
• von Tresckow, J., Cramer, P., Bahlo, J., Robrecht, S., Langerbeins, P., Fink, A.M., Al-Sawaf, O., Illmer, T., Klaproth, H., Estenfelder, S., Ritgen, M., Fischer, K., Wendtner, C.M., Kreuzer, K.A., Stilgenbauer, S., Böttcher, S., Eichhorst, B.F., and Hallek, M. (2019). CLL2-BIG: sequential treatment with bendamustine, ibrutinib and obinutuzumab (GA101) in chronic lymphocytic leukemia. Leukemia 33, 1161-1172. 10.1038/s41375-018-0313-8.
• Von Tresckow, J., Cramer, P., De Silva, N., Bahlo, J., Robrecht, S., Langerbeins, P., Fink, A.M., Al-Sawaf, O., Furstenau, M., Illmer, T., Klaproth, H., Tausch, E., Ritgen, M., Fischer, K., Wendtner, C.M., Kreuzer, K.A., Stilgenbauer, S., Böttcher, S., Eichhorst, B.F., and Hallek, M. (2019). Sequential Treatment with Bendamustine, Obinutuzumab (GA101) and Ibrutinib in Chronic Lymphocytic Leukemia (CLL): Final Results of the CLL2-BIG Trial of the German CLL Study Group (GCLLSG). Blood 134. 10.1182/blood-2019-125895.
• von Tresckow, J., Eichhorst, B., Bahlo, J., and Hallek, M. (2019). The Treatment of Chronic Lymphatic Leukemia. Deutsches Arzteblatt International 116, 41-46. 10.3238/arztebl.2019.0041.
• Weiss, J., Peifer, M., Herling, C.D., Frenzel, L.P., and Hallek, M. (2019). Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia (Comment to Tausch et al.). Haematologica 104, E540-E540. 10.3324/haematol.2019.232835.

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Matthias Hammerschmidt

• Turpin-Nolan SM, Hammerschmidt P, Chen W, Jais A, Timper K, Awazawa M, Brodesser S, Brüning JC (2019). CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Rep. 2019 Jan 2;26(1):1-10.e7. doi: 10.1016/j.celrep.2018.12.031

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Robert Hansel-Hertsch  

• Krafcikova M, Dzatko S, Caron C, Granzhan A, Fiala R, Loja T, Teulade-Fichou MP, Fessl T, Hänsel-Hertsch R, Mergny JL, Foldynova-Trantirkova S, Trantirek L (2019). Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy. J Am Chem Soc. (2019), 34: 13281-13285
• Krafcikova M, Hänsel-Hertsch R, Trantirek L, Foldynova-Trantirkova S (2019). In Cell NMR Spectroscopy: Investigation of G-Quadruplex Structures Inside Living Xenopus laevis Oocytes. Methods Mol Biol. 2019;2035:397-405. doi: 10.1007/978-1-4939-9666-7_25

Jan Hoeijmakers 

• Alyodawi K, Vermeij WP, Omairi S, Kretz O, Hopkinson M, Solagna F, Joch B, Brandt RMC, Barnhoorn S, van Vliet N, Ridwan Y, Essers J, Mitchell R, Morash T, Pasternack A, Ritvos O, Matsakas A, Collins-Hooper H, Huber TB, Hoeijmakers JHJ, Patel K (2019). Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling. J Cachexia Sarcopenia Muscle. 2019 Jun;10(3):662-686. doi: 10.1002/jcsm.12404. Epub 2019 Mar 27. PMID: 30916493
• Jager M, Blokzijl F, Kuijk E, Bertl J, Vougioukalaki M, Janssen R, Besselink N, Boymans S, de Ligt J, Pedersen JS, Hoeijmakers J, Pothof J, van Boxtel R, Cuppen E (2019). Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer. Genome Res. 2019 Jul;29(7):1067-1077. doi: 10.1101/gr.246223.118. Epub 2019 Jun 20 
• Lans H, Hoeijmakers JHJ, Vermeulen W, Marteijn JA (2019). The DNA damage response to transcription stress. Nat Rev Mol Cell Biol. 2019 Sep 26. doi: 10.1038/s41580-019-0169-4. [Epub ahead of print] PMID: 31558824  
• Milanese C, Bombardieri CR, Sepe S, Barnhoorn S, Payán-Goméz C, Caruso D, Audano M, Pedretti S, Vermeij WP, Brandt RMC, Gyenis A, Wamelink MM, de Wit AS, Janssens RC, Leen R, van Kuilenburg ABP, Mitro N, Hoeijmakers JHJ, Mastroberardino PG (2019). DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering. Nat Commun. 2019 Oct 25;10(1):4887. doi: 10.1038/s41467-019-12640-5. PMID: 31653834
• Theil AF, Botta E, Raams A, Smith DEC, Mendes MI, Caligiuri G, Giachetti S, Bione S, Carriero R, Liberi G, Zardoni L, Swagemakers SMA, Salomons GS, Sarasin A, Lehmann A, van der Spek PJ, Ogi T, Hoeijmakers JHJ, Vermeulen W, Orioli D (2019). Bi-allelic TARS Mutations Are Associated with Brittle Hair Phenotype. Am J Hum Genet. 2019 Aug 1;105(2):434-440. doi: 10.1016/j.ajhg.2019.06.017. PMID: 31374204  

Thorsten Hoppe       

• Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB. Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, Hoppe T, Kaeberlein M, Katajisto P, Kennedy BK, Lal U, Martin-Villalba A, Moskalev AA, Ozerov I, Petr MA, Reason, Rubinsztein DC, Tyshkovskiy A, Vanhaelen Q, Zhavoronkov A, Scheibye-Knudsen M (2019). Latest advances in aging research and drug discovery. Aging-US. 2019 Nov 21;11. doi: 10.18632/aging.102487
• Finger F, Ottens F, Springhorn A, Drexel T, Proksch L, Metz S, Cochella L, Hoppe T (2019). Olfaction regulates organismal proteostasis and longevity via miRNA-dependent signaling. Nat. Metab. 2019 Mar;1(3):350-359. doi: 10.1038/s42255-019-0033-z. Epub 2019 Feb 18
• Kumsta C, Chang JT, Lee R, Tan EP, Yang Y, Loureiro R, Choy EH, Lim SHY, Saez I, Springhorn A, Hoppe T, Vilchez D, Hansen M (2019). The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy. Nat Commun. 10: 5648.
• Ottens F, Finger F, Hoppe T (2019). Wie der Geruch von Nahrung Stoffwechsel und Altern beeinflusst. Nutrition News. 3, 3-5 
• Springhorn A, Hoppe T (2019). Western blot analysis of the autophagosomal membrane protein LGG-1/LC3 in Caenorhabditis elegans. Method Enzymol. 2019;619:319-336. doi: 10.1016/bs.mie.2018.12.034. Epub 2019 Feb 4        

Tamas Horvath      

• Seli E, Wang T, Horvath TL (2019). Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging. Fertil Steril. 2019 Feb;111(2):197-204. doi: 10.1016/j.fertnstert.2018.11.048
• Stutz B, Nasrallah C, Nigro M, Curry D, Liu ZW, Gao XB, Elsworth JD, Mintz L, Horvath TL (2019). Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activity. Mol Metab. 2019 Jun;24:120-138. doi: 10.1016/j.molmet.2019.02.005. Epub 2019 Feb 21

Pitter Huesgen  

• Dahms SO, Demir F, Huesgen PF, Thorn K, Brandstetter H (2019). Sirtilins - the new old members of the vitamin K-dependent coagulation factor family. J Thromb Haemost, 17:470-81
• Demir F, Perrar A, Huesgen PF (2019) Das maßgeschneiderte Proteom: Proteinmodifikation durch Proteolyse. BIOspektrum. 25:41-44
• Drescher HK, Weiskirchen R, Fülöp A, Hopf C, de San Román EG, Huesgen PF, de Bruin A, Bongiovanni L, Christ A, Tolba R, Trautwein C, Kroy DC (2019). The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH). Front Physiol. 10:770
• Elfgen A, Hupert M, Bochinsky K, Tusche M, González de San Román Martin E, Gering I, Sacchi S, Pollegioni L, Huesgen PF, Hartmann R, Santiago-Schübel B, Kutzsche J, Willbold D (2019). Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers. Sci Rep. 9:5715
• Huber CV, Jakobs B, Mishra LS, Niedermaier S, Stift M, Winter G, Adamska I, Funk C, Huesgen PF, Funck D (2019). DEG10 is important for mitochondrial proteostasis, root growth and seed yield in Arabidopsis. J Exp Bot. 2019 Oct 15;70(19):5423-5436. doi: 10.1093/jxb/erz294
• Krichel C, Möckel C, Schillinger O, Huesgen PF, Sticht H, Strodel B, Weiergräber OH, Willbold D, Neudecker P (2019). Solution structure of the autophagy-related protein LC3C reveals a polyproline II motif on a mobile tether with phosphorylation site. Sci Rep. 9:14167
• Misas-Villamil J, Mueller AN, Demir F, Meyer U, Breuer M, Dauben H, Win J, Huesgen PF, Doehlemann G (2019). The fungal effector Pit2 acts as molecular mimicry to suppress plant immunity via an inter-kingdom conserved motif. Nat Commun.10:1576
• Niedermaier S, Huesgen PF (2019). Positional proteomics for identification of secreted proteoforms released by site-specific membrane protein processing. Biochim Biophys Acta Proteins Proteom, 2019 Dec;1867(12):140138. doi: 10.1016/j.bbapap.2018.09.004. Epub 2018 Sep 20
• Perrar A, Dissmeyer N, Huesgen PF (2019). New beginnings and new ends – Methods for large-scale characterization of protein termini and their use in plant biology. J Exp Bot. 70:2021-38
• Perrar, A., Demir, F., and Huesgen, P.F. (2019). Site specific proteolytic processing - An irreversible contribution to plant immune signaling? Mol Plant Microbe In 32, 210-210.
• Soares A, Niedermaier S, Faro R, Loos A, Manadas B, Faro C, Huesgen PF, Cheung AY, Simões I (2019). An atypical aspartic protease modulates lateral root development in Arabidopsis thaliana. J Exp Bot. 70:2157-71
• Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM (2019). The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 95:333-49
• Villamil, J.C.M., Mueller, A.N., Demir, F., Meyer, U., Ökmen, B., Hüynck, J.S., Breuer, M., Dauben, H., Win, J., Huesgen, P.F., and Doehlemann, G. (2019). A fungal substrate mimicking molecule suppresses plant immunity via an inter-kingdom conserved motif. Nat Commun 10. ARTN 1576. 10.1038/s41467-019-09472-8.
• Weng SSH, Demir F, Ergin EK, Dirnberger S, Uzozie A, Tuscher D, Nierves L, Tsui J, Huesgen PF, Lange PF (2019). Sensitive determination of proteolytic proteoforms in limited microscale proteome samples. Mol Cell Proteomics. 2019 Nov;18(11):2335-2347. doi: 10.1074/mcp.TIR119.001560. Epub 2019 Aug 30 
• Zelanis A, Oliveira AK, Prudova A, Huesgen PF, Tashima AK, Kizhakkedathu JN, Overall CM, de Toledo Serrano SM (2019). Deep profiling of the cleavage specificity and human substrates of snake venom metalloprotease HF3 by PICS using proteome derived peptide libraries and TAILS N-terminomics. J Proteome Res. 18:3419-28  

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Sandra Iden

• Dias Gomes M, Letzian S, Saynisch M, Iden S (2019). Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity. Nat Commun. 2019; 10: 3362. Published online 2019 Jul 29. doi: 10.1038/s41467-019-11325-3

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Frank Jessen

• Bainbridge, W.A., Berron, D., Schutze, H., Cardenas-Blanco, A., Metzger, C., Dobisch, L., Bittner, D., Glanz, W., Spottke, A., Rudolph, J., Brosseron, F., Buerger, K., Janowitz, D., Fliessbach, K., Heneka, M., Laske, C., Buchmann, M., Peters, O., Diesing, D., Li, S., Priller, J., Spruth, E.J., Altenstein, S., Schneider, A., Kofler, B., Teipel, S., Kilimann, I., Wiltfang, J., Bartels, C., Wolfsgruber, S., Wagner, M., Jessen, F., Baker, C.I., and Duzel, E. (2019). Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment. Alzheimers Dement (Amst) 11, 610-618. 10.1016/j.dadm.2019.07.005.
• Baker, E., Sims, R., Leonenko, G., Frizzati, A., Harwood, J.C., Grozeva, D., Gerad/Perades, Charge, Adgc, Eadi, consortia, I., Morgan, K., Passmore, P., Holmes, C., Powell, J., Brayne, C., Gill, M., Mead, S., Bossu, P., Spalletta, G., Goate, A.M., Cruchaga, C., Maier, W., Heun, R., Jessen, F., Peters, O., Dichgans, M., FroLich, L., Ramirez, A., Jones, L., Hardy, J., Ivanov, D., Hill, M., Holmans, P., Allen, N.D., Morgan, B.P., Seshadri, S., Schellenberg, G.D., Amouyel, P., Williams, J., and Escott-Price, V. (2019). Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease. Plos One 14, e0218111. 10.1371/journal.pone.0218111.
• Berron, D., Cardenas-Blanco, A., Bittner, D., Metzger, C.D., Spottke, A., Heneka, M.T., Fliessbach, K., Schneider, A., Teipel, S.J., Wagner, M., Speck, O., Jessen, F., and Duzel, E. (2019). Higher CSF Tau Levels Are Related to Hippocampal Hyperactivity and Object Mnemonic Discrimination in Older Adults. J Neurosci 39, 8788-8797. 10.1523/JNEUROSCI.1279-19.2019.
• Betts, M.J., Cardenas-Blanco, A., Kanowski, M., Spottke, A., Teipel, S.J., Kilimann, I., Jessen, F., and Duzel, E. (2019). Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Abeta levels. Alzheimers Dement (Amst) 11, 281-285. 10.1016/j.dadm.2019.02.001.
• Brueggen, K., Dyrba, M., Cardenas-Blanco, A., Schneider, A., Fliessbach, K., Buerger, K., Janowitz, D., Peters, O., Menne, F., Priller, J., Spruth, E., Wiltfang, J., Vukovich, R., Laske, C., Buchmann, M., Wagner, M., Roske, S., Spottke, A., Rudolph, J., Metzger, C.D., Kilimann, I., Dobisch, L., Duzel, E., Jessen, F., Teipel, S.J., and Group, D.S. (2019). Structural integrity in subjective cognitive decline, mild cognitive impairment and Alzheimer's disease based on multicenter diffusion tensor imaging. J Neurol 266, 2465-2474. 10.1007/s00415-019-09429-3.
• Dafsari, F.S., Bewernick, B., Biewer, M., Christ, H., Domschke, K., Froelich, L., Hellmich, M., Luppa, M., Peters, O., Ramirez, A., Riedel-Heller, S., Schramm, E., Vry, M.S., Wagner, M., Hautzinger, M., and Jessen, F.(2019). Cognitive behavioural therapy for the treatment of late life depression: study protocol of a multicentre, randomized, observer-blinded, controlled trial (CBTlate). BMC Psychiatry 19, 423. 10.1186/s12888-019-2412-0.
• Dalmasso MC, Brusco LI, Olivar N, Muchnik C, Hanses C, Milz E, Becker J, Heilmann-Heimbach S, Hoffmann P, Prestia FA, Galeano P, Avalos MSS, Martinez LE, Carulla ME, Azurmendi PJ, Liberczuk C, Fezza C, Sampaño M, Fierens M, Jemar G, Solis P, Medel N, Lisso J, Sevillano Z, Bosco P, Bossù P, Spalletta G, Galimberti D, Mancuso M, Nacmias B, Sorbi S, Mecocci P, Pilotto A, Caffarra P, Panza F, Bullido M, Clarimon J, Sánchez-Juan P, Coto E, Sanchez-Garcia F, Graff C, Ingelsson M, Bellenguez C, Castaño EM, Kairiyama C, Politis DG, Kochen S, Scaro H, Maier W, Jessen F, Mangone CA, Lambert JC, Morelli L, Ramirez A (2019). Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer's disease. Transl Psychiatry. 2019 Jan 31;9(1):55. doi: 10.1038/s41398-019-0394-9. PubMed PMID: 30705288; PubMed Central PMCID: PMC6355764
• Escher CM, Sannemann L, Jessen F (2019). Stress and Alzheimer's disease. J Neural Transm (Vienna). 2019 Feb 20. doi: 10.1007/s00702-019-01988-z. [Epub ahead of print]
• Frisoni, G.B., Barkhof, F., Altomare, D., Berkhof, J., Boccardi, M., Canzoneri, E., Collij, L., Drzezga, A., Farrar, G., Garibotto, V., Gismondi, R., Gispert, J.D., Jessen, F., Kivipelto, M., Lopes Alves, I., Molinuevo, J.L., Nordberg, A., Payoux, P., Ritchie, C., Savicheva, I., Scheltens, P., Schmidt, M.E., Schott, J.M., Stephens, A., van Berckel, B., Vellas, B., Walker, Z., and Raffa, N. (2019). AMYPAD Diagnostic and Patient Management Study: Rationale and design. Alzheimers Dement 15, 388-399. 10.1016/j.jalz.2018.09.003.
• Haidl TK, Seves M, Eggers S, Rostamzadeh A, Genske A, Jünger S, Woopen C, Jessen F, Ruhrmann S, Vogeley K (2019). Health literacy in clinical-high-risk individuals for psychosis: A systematic mixed-methods review. Early Interv Psychiatry. 2019 Jan 27. doi: 10.1111/eip.12776. [Epub ahead of print] Review. PubMed PMID: 30688012
• Hoenig, M.C., Bischof, G.N., Onur, O.A., Kukolja, J., Jessen, F., Fliessbach, K., Neumaier, B., Fink, G.R., Kalbe, E., Drzezga, A., van Eimeren, T., and Alzheimer's Disease Neuroimaging, I. (2019). Level of education mitigates the impact of tau pathology on neuronal function. Eur J Nucl Med Mol Imaging 46, 1787-1795. 10.1007/s00259-019-04342-3.
• Hu, X., Teunissen, C.E., Spottke, A., Heneka, M.T., Duzel, E., Peters, O., Li, S., Priller, J., Buerger, K., Teipel, S., Laske, C., Verfaillie, S.C.J., Barkhof, F., Coll-Padros, N., Rami, L., Molinuevo, J.L., van der Flier, W.M., and Jessen, F.(2019). Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies. Alzheimers Dement 15, 185-193. 10.1016/j.jalz.2018.09.002.
• Jagust W, Jack CR Jr, Bennett DA, Blennow K, Haeberlein SB, Holtzman DM, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Sperling R (2019). "Alzheimer's disease" is neither "Alzheimer's clinical syndrome" nor "dementia". Alzheimers Dement. 2019 Jan;15(1):153-157. doi: 10.1016/j.jalz.2018.11.002. PubMed PMID: 30642435
• Jessen F (2019). Early detection of Alzheimer's disease and approaches for prevention. BundesgesundheitsblattGesundheitsforschung Gesundheitsschutz. 2019 Jan 24. doi: 10.1007/s00103-019-02877-2. [Epub ahead of print] Review. German. PubMed PMID: 30680409
• Jessen, F. (2019). Commentary: Combination Therapy for Alzheimer's Disease - The Next Step. J Prev Alzheimers Dis 6, 179. 10.14283/jpad.2019.18.
• Jessen, F. (2019). Refining the understanding of typical Alzheimer disease. Nat Rev Neurol 15, 623-624. 10.1038/s41582-019-0259-0.
• Jessen, F. (2019). What are we trying to prevent in Alzheimer disease? Dialogues Clin Neurosci 21, 27-34. 10.31887/DCNS.2019.21.1/fjessen.
• Jiang, X., Faber, J., Giordano, I., Machts, J., Kindler, C., Dudesek, A., Speck, O., Kamm, C., Duzel, E., Jessen, F., Spottke, A., Vielhaber, S., Boecker, H., Klockgether, T., and Scheef, L. (2019). Characterization of Cerebellar Atrophy and Resting State Functional Connectivity Patterns in Sporadic Adult-Onset Ataxia of Unknown Etiology (SAOA). Cerebellum 18, 873-881. 10.1007/s12311-019-01072-y.
• Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roschupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L,  Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall  DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG,  Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y; Alzheimer Disease Genetics Consortium (ADGC),; European Alzheimer’s Disease Initiative (EADI),; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE),; Genetic and Environmental Risk inAD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES),, Pilotto A, Bullido MJ, Peters O, Crane PK, BennettD, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL,Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM,Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, C O'Donovan M, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA (2019). Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 Mar;51(3):414-430. doi:10.1038/s41588-019-0358-2. Epub 2019 Feb 28. PubMed PMID: 30820047
• Lardenoije, R., Roubroeks, J.A.Y., Pishva, E., Leber, M., Wagner, H., Iatrou, A., Smith, A.R., Smith, R.G., Eijssen, L.M.T., Kleineidam, L., Kawalia, A., Hoffmann, P., Luck, T., Riedel-Heller, S., Jessen, F., Maier, W., Wagner, M., Hurlemann, R., Kenis, G., Ali, M., Del Sol, A., Mastroeni, D., Delvaux, E., Coleman, P.D., Mill, J., Rutten, B.P.F., Lunnon, K., Ramirez, A., and van den Hove, D.L.A. (2019). Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood. Clin Epigenetics 11, 164. 10.1186/s13148-019-0755-5.
• Meiberth D, Rapp MA, Jessen F (2019). Memory Clinics in Germany - Results of a Hospital Survey. Psychiatr Prax. 2019 Jan 14. doi: 10.1055/a-0825-9049. [Epub ahead of print] German. PubMed PMID: 30641612
• Miebach, L., Wolfsgruber, S., Frommann, I., Fliessbach, K., Jessen, F., Buckley, R., and Wagner, M. (2019). Cognitive Complaints in Memory Clinic Patients and in Depressive Patients: An Interpretative Phenomenological Analysis. Gerontologist 59, 290-302. 10.1093/geront/gnx208.
• Miebach, L., Wolfsgruber, S., Polcher, A., Peters, O., Menne, F., Luther, K., Incesoy, E., Priller, J., Spruth, E., Altenstein, S., Buerger, K., Catak, C., Janowitz, D., Perneczky, R., Utecht, J., Laske, C., Buchmann, M., Schneider, A., Fliessbach, K., Kalbhen, P., Heneka, M.T., Brosseron, F., Spottke, A., Roy, N., Teipel, S.J., Kilimann, I., Wiltfang, J., Bartels, C., Duzel, E., Dobisch, L., Metzger, C., Meiberth, D., Ramirez, A., Jessen, F., and Wagner, M. (2019). Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study. Alzheimers Res Ther 11, 66. 10.1186/s13195-019-0515-y.
• Rodriguez-Gomez, O., Rodrigo, A., Iradier, F., Santos-Santos, M.A., Hundemer, H., Ciudin, A., Sannemann, L., Zwan, M., Glaysher, B., Wimo, A., Bonn, J., Johansson, G., Rodriguez, I., Alegret, M., Gove, D., Pino, S., Trigueros, P., Kivipelto, M., Mathews, B., Ciudad, A., Ferreira, D., Bintener, C., Gurruchaga, M., Westman, E., Belger, M., Valero, S., Maguire, P., Krivec, D., Kramberger, M., Simo, R., Garro, I.P., Visser, P.J., Dumas, A., Georges, J., Jessen, F., Winblad, B., Shering, C., Stewart, N., Campo, L., Boada, M., and Consortium, M. (2019). The MOPEAD project: Advancing patient engagement for the detection of "hidden" undiagnosed cases of Alzheimer's disease in the community. Alzheimers Dement 15, 828-839. 10.1016/j.jalz.2019.02.003.
• Roehr, S., Riedel-Heller, S.G., Kaduszkiewicz, H., Wagner, M., Fuchs, A., van der Leeden, C., Wiese, B., Werle, J., Bickel, H., Konig, H.H., Wolfsgruber, S., Pentzek, M., Weeg, D., Mamone, S., Weyerer, S., Brettschneider, C., Maier, W., Scherer, M., Jessen, F., and Luck, T. (2019). Is function in instrumental activities of daily living a useful feature in predicting Alzheimer's disease dementia in subjective cognitive decline? Int J Geriatr Psychiatry 34, 193-203. 10.1002/gps.5010.
• Scheef, L., Grothe, M.J., Koppara, A., Daamen, M., Boecker, H., Biersack, H., Schild, H.H., Wagner, M., Teipel, S., and Jessen, F. (2019). Subregional volume reduction of the cholinergic forebrain in subjective cognitive decline (SCD). Neuroimage Clin 21, 101612. 10.1016/j.nicl.2018.101612.
• Schüller CB, Kuhn J, Jessen F, Hu X (2019). Neuronal correlates of delay discounting in healthy subjects and its implication for addiction: an ALE meta-analysis study. Am J Drug Alcohol Abuse. 2019;45(1):51-66. doi:10.1080/00952990.2018.1557675. Epub 2019 Jan 11. PubMed PMID: 30632802
• Slot, R.E.R., Sikkes, S.A.M., Berkhof, J., Brodaty, H., Buckley, R., Cavedo, E., Dardiotis, E., Guillo-Benarous, F., Hampel, H., Kochan, N.A., Lista, S., Luck, T., Maruff, P., Molinuevo, J.L., Kornhuber, J., Reisberg, B., Riedel-Heller, S.G., Risacher, S.L., Roehr, S., Sachdev, P.S., Scarmeas, N., Scheltens, P., Shulman, M.B., Saykin, A.J., Verfaillie, S.C.J., Visser, P.J., Vos, S.J.B., Wagner, M., Wolfsgruber, S., Jessen, F., Alzheimer's Disease Neuroimaging, I., group, D.w., group, I.N.-p.s., group, S.-I.w., and van der Flier, W.M. (2019). Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia. Alzheimers Dement 15, 465-476. 10.1016/j.jalz.2018.10.003.
• Sun, Y., Wang, X., Wang, Y., Dong, H., Lu, J., Scheininger, T., Ewers, M., Jessen, F., Zuo, X.N., and Han, Y. (2019). Anxiety correlates with cortical surface area in subjective cognitive decline: APOE epsilon4 carriers versus APOE epsilon4 non-carriers. Alzheimers Res Ther 11, 50. 10.1186/s13195-019-0505-0.
• Teipel, S.J., Kuper-Smith, J.O., Bartels, C., Brosseron, F., Buchmann, M., Buerger, K., Catak, C., Janowitz, D., Dechent, P., Dobisch, L., Ertl-Wagner, B., Fliessbach, K., Haynes, J.D., Heneka, M.T., Kilimann, I., Laske, C., Li, S., Menne, F., Metzger, C.D., Priller, J., Pross, V., Ramirez, A., Scheffler, K., Schneider, A., Spottke, A., Spruth, E.J., Wagner, M., Wiltfang, J., Wolfsgruber, S., Duzel, E., Jessen, F., Dyrba, M., and group, D.s. (2019). Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness. J Alzheimers Dis 72, 455-465. 10.3233/JAD-190446.
• van Maurik, I.S., Slot, R.E.R., Verfaillie, S.C.J., Zwan, M.D., Bouwman, F.H., Prins, N.D., Teunissen, C.E., Scheltens, P., Barkhof, F., Wattjes, M.P., Molinuevo, J.L., Rami, L., Wolfsgruber, S., Peters, O., Jessen, F., Berkhof, J., van der Flier, W.M., and Alzheimer's Disease Neuroimaging, I. (2019). Personalized risk for clinical progression in cognitively normal subjects-the ABIDE project. Alzheimers Res Ther 11, 33. 10.1186/s13195-019-0487-y.
• Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padrós N, Bouwman FH, Slot RER, Wesselman LMP, Peters O, Luther K, Buerger K, Priller J, Laske C, Teipel S, Spottke A, Heneka MT, Düzel E, Drzezga A, Wiltfang J, Sikkes SAM, van der Flier WM, Jessen F, Euro-SCD working group (2019). Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimers Res Ther. 2019 Jan 17;11(1):8. doi: 10.1186/s13195-018-0463-y. PubMed PMID: 30654834; PubMed Central PMCID: PMC6337830

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Hamid Kashkar

• Ayachi O, Barlin M, Broxtermann PN, Kashkar H, Mauch C, Zigrino P (2019). The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival. Cell Oncol. 42:319-329
• Fritsch M, Günther SD, Schwarzer R, Albert MC, Schorn F, Werthenbach JP, Schiffmann LM, Stair N, Stocks H, Seeger JM, Lamkanfi M, Krönke M, Pasparakis M, Kashkar H (2019). Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. Nature. 2019, 575:683-687
• Gräb J, Suarez I, van Gumpel E, Winter S, Schreiber F, Esser A, Hölscher C, Fritsch M, Herb M, Schramm M, Wachsmuth L, Pallasch C, Pasparakis M, Kashkar H, Rybniker J (2019). Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition. Nat Commun. 10:688
• Habich M, Salscheider S, Murschall L, Hoehne M, Fischer M, Schorn F, Petrungaro C, Ali M, Erdogan A, Abou-Eid S, Kashkar H, Dengjel J, Riemer J (2019). Vectorial import via a metastable disulphide-linked complex allows for a quality control step and efficient import by the mitochondrial disulphide relay Cell Rep. 2019 Jan 15;26(3):759-774.e5. doi: 10.1016/j.celrep.2018.12.092
• Holzer T, Probst K, Etich J, Auler M, Georgieva V, Bluhm B, Frie C, Heilig J, Niehoff A, Nüchel J, Plomann M, Seeger JM, Kashkar H, Baris OR, Wiesner RJ, Brachvogel B (2019). Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases. J Cell Biol. 218(6):1853-1870
• Schiffmann LM, Fritsch M, Gebauer F, Günther SD, Stair NR, Seeger JM, Thangarajah F, Dieplinger G, Bludau M, Alakus H, Göbel H, Quaas A, Zander T, Hilberg F, Bruns CJ, Kashkar H, Coutelle O (2019). Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer. Br J Cancer. 2019 Jan;120(1):69-78. doi: 10.1038/s41416-018-0198-3. Epub 2018 Oct 31
• Schiffmann LM, Göbel H, Löser H, Schorn F, Werthenbach JP, Fuchs HF, Plum PS, Bludau M, Zander T, Schröder W, Bruns CJ, Kashkar H, Quaas A, Gebauer F. (2019). Elevated X-linked inhibitor of apoptosis protein (XIAP) expression uncovers detrimental prognosis in subgroups of neoadjuvant treated and T-cell rich esophageal adenocarcinoma. BMC Cancer. 2019, 19(1):531   

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Peter Kloppenburg

• Benkert J, Hess S, Roy S, Beccano-Kelly D, Wiederspohn N, Duda J, Simons C, Patil K, Gaifullina A, Mannal N, Dragicevic E, Spaich D, Müller S, Nemeth J, Hollmann H, Deuter N, Mousba Y, Kubisch C, Poetschke C, Striessnig J, Pongs O, Schneider T, Wade-Martins R, Patel S, Parlato R, Frank T, Kloppenburg P, Liss B (2019). Cav2.3 channels contribute to dopaminergic neuron loss in a model of Parkinson's disease. Nat Commun. 2019 Nov 8;10(1):5094. doi: 10.1038/s41467-019-12834-x. PMID: 31704946
• Benkert, J., Hess, S., Roy, S., Wiederspohn, N., Duda, J., Hollmann, H., Mueller, S., Poetschke, C., Parlato, R., Striessnig, J., Schneider, T., Frank, T., Kloppenburg, P., and Liss, B. (2019). Cav2.3 channels trigger selective dopaminergic neuron loss in Parkinson's disease. Acta Physiol 227.
• Murru S, Hess S, Barth E, Almajan ER, Schatton D, Hermans S, Brodesser S, Langer T, Kloppenburg P, Rugarli EI (2019). Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019 Aug;67(8):1526-1541. doi: 10.1002/glia.23626. Epub 2019 Apr 16
• Vogel S, Schäfer C, Hess S, Folz-Donahue K, Nelles M, Minassian A, Schwarz MK, Kukat C, Ehrlich M, Zaehres H, Kloppenburg P, Hoehn M, Aswendt M (2019). The in vivo timeline of differentiation of engrafted human neural progenitor cells. Stem Cell Res. 2019 May;37:101429. doi: 10.1016/j.scr.2019.101429. Epub 2019 Mar 25. PMID: 30933718   

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Natalia Kononenko

• Kononenko NL, Hartfil S, Willer J, Ferch J, Wolfenberg H, Pflueger HJ (2019). A population of descending tyraminergic/octopaminergic projection neurons of the insect. J Comp Neurol. Apr 15;527:1027-1038 (2019)
• Torres-Benito L, Schneider S, Rombo R, Ling KK, Grysko V, Upadhyay A, Kononenko NL, Rigo FW, Bennett CF, Wirth B (2019). NCALD antisense oligonucleotide-based therapy additionally to low-dose Nusinersen further ameliorates spinal muscular atrophy in mice. Am J Hum Genet. 2019 Jul 3;105(1):221-230. doi: 10.1016/j.ajhg.2019.05.008. Epub 2019 Jun 20
• Upadhyay A, Hosseinibarkooie M, Schneider S, Kaczmarek A, Torres-Benito L, Natalia Mendoza-Ferreira N, Overhoff M, Rombo R, Grysko V, Kye MJ, Kononenko NL, Wirth B (2019). Neurocalcin delta knockout impairs adult neurogenesis whereas half reduction is a safe therapeutic option for spinal muscular atrophy. Front Mol Neurosci. 2019 Feb 12. doi: 10.3389/fnmol.2019.00019

Tatiana Korotkova

• Mykytiuk, V., and Korotkova, T. (2019). Regulation of locomotion and reward seeking behaviour by the ventral tegmental area inputs onto the lateral hypothalamus. Acta Physiol 227.
• Petzold, A., Van den Munkhof, H., and Korotkova, T. (2019). The interaction of local and global circuits of the lateral hypothalamus orchestrates feeding behaviour in freely foraging mice. Acta Physiol 227.
• Ruud, J., Alber, J., Tokarska, A., Engstrom Ruud, L., Nolte, H., Biglari, N., Lippert, R., Lautenschlager, A., Cieslak, P.E., Szumiec, L., Hess, M.E., Bronneke, H.S., Kruger, M., Nissbrandt, H., Korotkova, T., Silberberg, G., Rodriguez Parkitna, J., and Bruning, J.C. (2019). The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons. Cell Rep 27, 3182-3198 e3189. 10.1016/j.celrep.2019.05.037.
• van den Munkhof, H.E., de los Santos, F.J., Petzold, A., and Korotkova, T. (2019). The role of the neurotensin circuitry in innate behaviours. Acta Physiol 227.

Thomas Krieg

• Chaigne, B., Clary, G., Le Gall, M., Dumoitier, N., Fernandez, C., Lofek, S., Chafey, P., Moinzadeh, P., Krieg, T., Denton, C.P., and Mouthon, L. (2019). Proteomic Analysis of Human Scleroderma Fibroblasts Response to Transforming Growth Factor-ß. Proteom Clin Appl 13. ARTN 1800069. 10.1002/prca.201800069.
• Eckes, B., Sawant, M.S., Leitinger, B., and Krieg, T. (2019). Cell - collagen interactions through collagen-binding integrins are dispensable for murine development. J Invest Dermatol 139, S325-S325. DOI 10.1016/j.jid.2019.07.646.
• Kreuter, M., Bonella, F., Blank, N., Siegert, E., Henes, J., Worm, M., Sunderkoetter, C., Schmalzing, M., Kreuter, A., Guenther, C., Susok, L., Zeidler, G., Koetter, I., Mueller-Ladner, U., Krieg, T., Juche, A., Schmeiser, T., Riemekasten, G., Aberer, E., Gaebelein-Wissing, N., Distler, J.H.W., Sárdy, M., Pfeiffer, C., Kuhr, K., Lorenz, H.M., Moinzadeh, P., and Hunzelmann, N. (2019). Does anti-acid treatment influence disease progression in SSc-ILD ? data from the German SSc-network. Eur Respir J 54. 10.1183/13993003.congress-2019.OA3595.
• Kreuter, M., Bonella, F., Blank, N., Siegert, E., Henes, J., Worm, M., Sunderkoetter, C., Schmalzing, M., Kreuter, A., Guenther, C., Susok, L., Zeidler, G., Koetter, I., Mueller-Ladner, U., Krieg, T., Juche, A., Schmeiser, T., Riemekasten, G., Aberer, E., Gaebelein-Wissing, N., Distler, J.H.W., Sárdy, M., Pfeiffer, C., Kuhr, K., Lorenz, H.M., Moinzadeh, P., and Hunzelmann, N. (2019). Long term outcomes of immunomodulatory drugs in SSc-ILD - data from the German SSc-network. Eur Respir J 54. 10.1183/13993003.congress-2019.PA5185.
• Kreuter, M., Bonella, F., Blank, N., Siegert, E., Henes, J., Worm, M., Sunderkoetter, C., Schmalzing, M., Kreuter, A., Guenther, C., Susok, L., Zeidler, G., Koetter, I., Mueller-Ladner, U., Krieg, T., Juche, A., Schmeiser, T., Riemekasten, G., Aberer, E., Gaebelein-Wissing, N., Distler, J.H.W., Sardy, M., Pfeiffer, C., Kuhr, K., Lorenz, H., Moinzadeh, P., and Hunzelmann, N. (2019). Predictors for the Development of Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD) - Data from the German SSc-Network. Am J Resp Crit Care 199.
• Krieg, T. (2019). Call for Research Projects on Pathogenesis, Diagnosis and Treatment of Scleroderma. Hautarzt 70, 149-149.
• Krieg, T. (2019). Call for Research Projects on the Pathogenesis, Diagnosis and Therapy of Scleroderma. Z Rheumatol 78, 30-30.
• Krieg, T. (2019). Dermatology in the Area of Conflict of the Progress of modern Medicine. J Dtsch Dermatol Ges17, 32-32.
• Sawant, M.S., Nüchel, J., Plomann, M., Krieg, T., and Eckes, B. (2019). Regulation of transforming growth factor beta bioavailability by phosphorylation. J Invest Dermatol 139, S323-S323. DOI 10.1016/j.jid.2019.07.637.
• Schönborn, K., Willenborg, S., Schulz, J., Quondamatteo, F., Eming, S., Niehoff, A., Imhoff, T., Koch, M., Krieg, T., and Eckes, B. (2019). Fibroblast-specific overexpression of collagen XII leads to a delay in skin repair. J Invest Dermatol 139, S322-S322. DOI 10.1016/j.jid.2019.07.630.
• Üstün Y, Reibetanz M, Brachvogel B, Nisch R, Eckes B, Zigrino P, Krieg T (2019). Dual role of laminin-511 in regulating melanocyte migration and differentiation. Matrix Biol. 80: 59-71. doi: 10.1016/j.matbio.2018.09.006

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Martin Krönke

• Fritsch M, Günther SD, Schwarzer R, Albert MC, Schorn F, Werthenbach JP, Schiffmann LM, Stair N, Stocks H, Seeger JM, Lamkanfi M, Krönke M, Pasparakis M, Kashkar H (2019). Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. Nature. 2019 Nov;575(7784):683-687. doi: 10.1038/s41586-019-1770-6. Epub 2019 Nov 20
• Herb M, Farid A, Gluschko A, Krönke M, Schramm M (2019). Highly Efficient Transfection of Primary Macrophages with In Vitro Transcribed mRNA. J Vis Exp. 2019 Nov 9;(153). doi: 10.3791/60143
• Herb M, Gluschko A, Wiegmann K, Farid A, Wolf A, Utermöhlen O, Krut O, Krönke M , Schramm M (2019). Mitochondrial reactive oxygen species license pro-inflammatory signaling through disulfide linkage of NEMO. Sci Signal. 2019 Feb 12;12(568):eaar5926. doi: 10.1126/scisignal.aar5926
• Hintzen, L., Karow, U., Khan, A., Kronke, M., Langmann, T., and Utermohlen, O. (2019). How do microglia cells respond to Zika virus infection? Scand J Immunol 90.
• Mertins, S., Higgins, P.G., Rodríguez, M.G., Borlon, C., Galleman, Q., Mertens, P., Seifert, H., Krönke, M., and Klimka, A. (2019). Generation and selection of antibodies for a novel immunochromatographic lateral flow test to rapidly identify OXA-23-like-mediated carbapenem resistance in. Journal of Medical Microbiology 68, 1021-1032. 10.1099/jmm.0.001015.
• Peters, F., Tellkamp, F., Brodesser, S., Wachsmuth, E., Tosetti, B., Karow, U., Bloch, W., Utermöhlen, O., Krönke, M., and Niessen, C.M. (2019). Epidermal barrier maintenance and morphogenesis are molecularly distinct and ceramide synthase 4 is a novel key player in epidermal barrier maintenance. J Invest Dermatol 139, S257-S257. DOI 10.1016/j.jid.2019.07.254.
• Utermöhlen O, Jakobshagen K, Blissenbach B, Wiegmann K, Merz T, Hefti JP, Krönke M (2019). Emergence of AnnexinVpos CD31neg CD42blow/neg extracellular vesicles in plasma of humans at extreme altitude. PLoS One.2019 Aug 1;14(8):e0220133  

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Marcus Krüger

• Behrens, A., Kreuzmayr, A., Manner, H., Koop, H., Lorenz, A., Schaefer, C., Plauth, M., Jetschmann, J.U., von Tirpitz, C., Ewald, M., Sackmann, M., Renner, W., Krüger, M., Schwab, D., Hoffmann, W., Engelke, O., Pech, O., Kullmann, F., Pampuch, S., Lenfers, B., Weickert, U., Schilling, D., Boehm, S., Beckebaum, S., Cicinnati, V., Erckenbrecht, J.F., Dumoulin, F.L., Benz, C., Rabenstein, T., Haltern, G., Balsliemke, M., de Mas, C., Kleber, G., Pehl, C., Vogt, C., Kiesslich, R., Fischbach, W., Koop, I., Kuehne, J., Breidert, M., Sass, N.L., May, A., Friedrich, C., Veitt, R., Porschen, R., Ellrichmann, M., Arlt, A., Schmitt, W., Dollhopf, M., Schmidbaur, W., Dignass, A., Schmitz, V., Labenz, J., Kaiser, G., Krannich, A., Barteska, N., and Ell, C. (2019). Acute sedation-associated complications in GI endoscopy (ProSed 2 Study): results from the prospective multicentre electronic registry of sedation-associated complications. Gut 68, 445-+. 10.1136/gutjnl-2015-311037.
• Frank D, Yusuf Rangrez A, Friedrich C, Dittmann S, Stallmeyer B, Yadav P, Bernt A, Schulze-Bahr E, Borlepawar A, Zimmermann WH, Peischard S, Seebohm G, Linke WA, Baba HA, Krüger M, Unger A, Usinger P, Frey N, Schulze-Bahr E (2019). Cardiac α-Actin (ACTC1) Gene Mutation Causes Atrial-Septal Defects Associated With Late-Onset Dilated Cardiomyopathy. Circ Genom Precis Med. 2019 Aug;12(8):e002491. doi: 10.1161/CIRCGEN.119.002491. Epub 2019 Aug 20
• Frömel, T., Kesavan, R., Siuda, D., Weigert, A., Popp, R., Krüger, M., and Fleming, I. (2019). Genetic suppressor element (GSE) 1 in megakaryopoiesis and platelet production. Acta Physiol 227.
• Gärtner S, Hundertmark T, Nolte H, Theofel I, Eren-Ghiani Z, Tetzner C, Duchow TB, Rathke C, Krüger M, Renkawitz-Pohl R (2019). Stage-specific testes proteomics of Drosophila melanogaster identifies essential proteins for male fertility. Eur J Cell Biol. 2019 Jun;98(2-4):103-115. doi: 10.1016/j.ejcb.2019.01.001. Epub 2019 Jan 17
• Hammerschmidt P, Ostkotte D, Nolte H, Gerl MJ, Jais A, Brunner H, Sprenger HG, Awazawa M, Nicholls HAT, Turpin-Nolan SM, Langer T, Krüger M, Brügger B, Brüning JC (2019). CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity. Cell. 2019 May 30;177(6):1536-1552.e23. doi: 10.1016/j.cell.2019.05.008   
• Izquierdo-Alvarez, E., Vorholt, D., Wiederstein, J., Lobastova, L., Blakemore, S.J., Krüger, M., Hansen, H., Bruns, H., Hallek, M., and Pallasch, C. (2019). Loss of TP53 modifies the quantity and protein load of extracellular vesicles in leukemic B-cells and influences functional crosstalk within the tumor microenvironment. Oncol Res Treat 42, 66-66.
• Jachimowicz RD, Bhavana VB, Beleggia F, Isensee J, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y (2019). UBQLN4 regulates double-strand break repair by repressing homologous recombination and is overexpressed in aggressive tumors, Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3
• Jachimowicz, R.D., Beleggia, F., Isensee, J., Velpula, B.B., Goergens, J., Bustos, M.A., Doll, M.A., Shenoy, A., Checa-Rodriguez, C., Wiederstein, J.L., Baranes-Bachar, K., Bartenhagen, C., Hertwig, F., Teper, N., Nishi, T., Schmitt, A., Distelmaier, F., Lüdecke, H.J., Albrecht, B., Krüger, M., Schumacher, B., Geiger, T., Hoon, D.S.B., Huertas, P., Fischer, M., Hucho, T., Peifer, M., Ziv, Y., Reinhardt, H.C., Wieczorek, D., and Shiloh, Y. (2019). UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell 176, 505-+. 10.1016/j.cell.2018.11.024.
• Klapproth S, Bromberger T, Türk C, Krüger M, Moser M (2019). A kindlin-3-leupaxin-paxillin signaling pathway regulates podosome stability. J Cell Biol. 2019 Oct 7;218(10):3436-3454. doi: 10.1083/jcb.201903109. Epub 2019 Sep 19   
• Koser, F., Abdellatif, M., Türk, C., Krüger, M., Sedej, S., and Linke, W.A. (2019). Unbiased screen of the cardiac proteome and effect of spermidine therapy on titin properties in a rat model of heart failure with preserved ejection fraction (HFpEF). Acta Physiol 227.
• Krüger, M., Melnik, D., Kopp, S., Buken, C., Sahana, J., Bauer, J., Wehland, M., Hemmersbach, R., Corydon, T.J., Infanger, M., and Grimm, D. (2019). Fighting Thyroid Cancer with Microgravity Research. International Journal of Molecular Sciences 20. ARTN 2553. 10.3390/ijms20102553.
• Lim, R., Sugino, T., Nolte, H., Andrade, J., Zimmermann, B., Shi, C., Doddaballapur, A., Ong, Y.T., Wilhelm, K., Fasse, J.W.D., Ernst, A., Kaulich, M., Husnjak, K., Boettger, T., Guenther, S., Braun, T., Krüger, M., Benedito, R., Dikic, I., and Potente, M. (2019). Deubiquitinase USP10 regulates Notch signaling in the endothelium. Science 364, 188-+. 10.1126/science.aat0778.
• Luxenburger, A., Schmidt, D., Ianes, C., Pichlo, C., Krüger, M., von Drathen, T., Brunstein, E., Gainsford, G.J., Baumann, U., Knippschild, U., and Peifer, C. (2019). Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds. Molecules 24. ARTN 873. 10.3390/molecules24050873.
• MacVicar T, Ohba Y, Nolte H, Mayer FC, Tatsuta T, Sprenger HG, Lindner B, Zhao Y, Li J, Bruns C, Krüger M, Habich M, Riemer J, Schwarzer R, Pasparakis M, Henschke S, Brüning JC, Zamboni N, Langer T (2019). Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature. 2019 Nov;575(7782):361-365. doi: 10.1038/s41586-019-1738-6. Epub 2019 Nov 6
• Nassef, M.Z., Kopp, S., Melnik, D., Corydon, T.J., Sahana, J., Krüger, M., Wehland, M., Bauer, T.J., Liemersdorf, C., Hemmersbach, R., Infanger, M., and Grimm, D. (2019). Short-Term Microgravity Influences Cell Adhesion in Human Breast Cancer Cells. International Journal of Molecular Sciences 20. ARTN 5730. 10.3390/ijms20225730.
• Rehorst WA, Thelen MP, Nolte H, Türk C, Cirak S, Peterson JM, Wong GW, Wirth B, Krüger M, Winter D, Kye MJ (2019). Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy. Acta Neuropathol Commun. 2019 Oct 15;7(1):154. doi: 10.1186/s40478-019-0806-3
• Richter AM, Küster MM, Woods ML, Walesch SK, Gökyildirim MY, Krüger M, Dammann RH (2019). RASSF10 Is a TGFß-Target That Regulates ASPP2 and E-Cadherin Expression and Acts as Tumor Suppressor That Is Epigenetically Downregulated in Advanced Cancer. Cancers (Basel). 2019 Dec 8;11(12):1976. doi: 10.3390/cancers11121976.
• Ruud J, Alber J, Tokarska A, Engström Ruud L, Nolte H, Biglari N, Lippert R, Lautenschlager Ä, Cieślak PE, Szumiec Ł, Hess ME, Brönneke HS, Krüger M, Nissbrandt H, Korotkova T, Silberberg G, Parkitna JR, Brüning JC (2019). The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons. Cell Rep. 27(11), 3182-198  
• Saul VV, Seibert M, Krüger M, Jeratsch S, Kracht M, Schmitz ML (2019). ULK1/2 restricts the formation of inducible SINT-speckles, a new class of membrane-less organelles controlling the threshold of TBK1 activation. iScience. 19, 527-44
• Seibert M, Krüger M, Watson NA, Sen O, Daum JR, Slotman JA, Braun T, Houtsmuller AB, Gorbsky GJ, Jacob R, Kracht M, Higgins JMG Schmitz ML (2019). CDK1-mediated phosphorylation at the novel histone modification site H2B serine 6 is required for mitotic chromosome segregation. J Cell Biol. 2019 Apr 1;218(4):1164-1181. doi: 10.1083/jcb.201806057. Epub 2019 Feb 14  
• Steiner C, Nolte H, Azizan A, Krüger M, Denecke M, Rehorek A (2019). Quantitative proteomics for monitoring microbial dynamics in activated sludge from landfill leachate treatment. Environ Sci. : Water Res. Technol. 5(6), 1092-1101        

Leo Kurian

• Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling J, Dodzian J, Lehmann K, Vargas N, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano D, Kurian L (2019). Loss of genomic integrity by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep. 2019 Apr;20(4). pii: e47407. doi: 10.15252/embr.201847407. Epub 2019 Mar 18
• Bender D, Kaczmarek AT, Santamaria-Araujo JA, Stueve B, Waltz S, Bartsch D, Kurian L, Cirak S, Schwarz G (2019). Impaired mitochondrial maturation of sulfite oxidase in a patient with severe sulfite oxidase deficiency. Hum Mol Genet. 2019 Sep 1;28(17):2885-2899. doi: 10.1093/hmg/ddz109 
• Frank S, Ahuja G, Bartsch D, Russ N, Yao W,  Kuo JC, Derks JP,  Akhade VS, Kargapolova Y, Georgomanolis T, Messling J, Gramm M, Brant L, Rehimi R, Vargas NE, Kuroczik, Yang TP, Sahito RGA, Franzen J, Hescheler J, Sachinidis A, Peifer M, Rada-Iglesias A, Kanduri M, Costa IG, Kanduri C, Papantonis A, Kurian L (2019). yylncT defines a class of divergently-transcribed lncRNAs and safeguards the T-mediated mesodermal commitment of human PSCs. Cell Stem Cell. 2019 Feb 7;24(2):318-327.e8. doi: 10.1016/j.stem.2018.11.005. Epub 2018 Dec 13
• Keller, T., Wengenroth, L., Smorra, D., Probst, K., Kurian, L., Kribs, A., and Brachvogel, B. (2019). Novel DRAQ5™/SYTOX® Blue Based Flow Cytometric Strategy to Identify and Characterize Stem Cells in Human Breast Milk. Cytom Part B-Clin Cy 96, 480-489. 10.1002/cyto.b.21748.         
• Kuo CC, Hanzelmann S, Sentürk N, Frank S, Zajzon B, Derks JP, Akhade VS, Ahuja G, Kanduri C, Grummt I,Kurian L, Costa IG (2019).  Detection of RNA–DNA binding sites in long noncoding RNAs. Nucleic Acids Res. 2019 Apr 8;47(6):e32. doi: 10.1093/nar/gkz037              

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Thomas Langer

• Ahola, S., Langer, T. , and MacVicar, T. (2019). Mitochondrial Proteolysis and Metabolic Control. Csh Perspect Biol11. ARTN a033936. 10.1101/cshperspect.a033936.
• Hahn O, Drews LF, Nguyen A, Tatsuta T, Gkioni L, Hendrich O, Zhang Q, Langer T, Pletcher S, Wakelam MJO, Beyer A, Grönke S, Partridge L (2019). A nutritional memory effect counteracts the benefits of dietary restriction in old mice. Nat Metab. 1059–1073  
• Hammerschmidt P, Ostkotte D, Nolte H, Gerl MJ, Jais A, Brunner HL, Sprenger HG, Awazawa M, Nicholls HT, Turpin-Nolan SM, Langer T, Krüger M, Brügger B, Brüning JC (2019). CerS6-derived sphingolipids interact with Mff and promote mitochondrial fragmentation in obesity. Cell. 2019 May 30;177(6):1536-1552.e23. doi: 10.1016/j.cell.2019.05.008 
• MacVicar T, Ohba Y, Nolte H, Mayer FC, Tatsuta T, Sprenger HG, Lindner B, Zhao Y, Li J, Bruns C, Krüger M, Habich M, Riemer J, Scharzer R, Pasparakis M, Henschke S, Brüning JC, Zamboni N, Langer T (2019). Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature. 2019 Nov;575(7782):361-365. doi: 10.1038/s41586-019-1738-6. Epub 2019 Nov 6
• Miliara X, Tatsuta T, Berry JL, Rouse SL, Solak K, Chorev DS, Wu D, Robinson CV, Matthews S, Langer T(2019). Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins. Nat Commun. 2019 Mar 8;10(1):1130. doi: 10.1038/s41467-019-09089-x
• Murru S, Hess S, Barth E, Almajan ER, Schatton D, Hermans S, Brodesser S, Langer T, Kloppenburg P, Rugarli EI (2019). Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019 Aug;67(8):1526-1541. doi: 10.1002/glia.23626. Epub 2019 Apr 16
• Odendall, F., Backes, S., Tatsuta, T., Weill, U., Schuldiner, M., Langer, T. , Herrmann, J.M., Rapaport, D., and Dimmer, K.S. (2019). The mitochondrial intermembrane space-facing proteins Mcp2 and Tgl2 are involved in yeast lipid metabolism. Mol Biol Cell 30, 2681-2694. 10.1091/mbc.E19-03-0166.
• Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin PA, Baraibar M, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M (2019). Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy. Embo J.2019 Jan 3;38(1). pii: e99576. doi: 10.15252/embj.201899576. Epub 2018 Nov12
• Richter F, Dennerlein S, Nikolov M, Jans D, Naumenko N, Aich A, MacVicar T, Linden A, Jakobs S, Urlaub H, Langer T, Rehling P (2019). ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. J Cell Biol. 4;218(2):598-614. doi: 10.1083/jcb.201806093 
• Sprenger HS, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2019). Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 2019 Jan;11(1). pii: e9288. doi: 10.15252/emmm.201809288
• Sprenger, H.G., and Langer, T.  (2019). The Good and the Bad of Mitochondrial Breakups. Trends in Cell Biology 29, 888-900. 10.1016/j.tcb.2019.08.003.    
• Wani, G.A., Wendler, S., Sprenger, H.G., Göbel, J., Seeger, J., Fernando, B., Frese, C., Langer, T. , and Bergami, M. (2019). The mitochondrial peptidase YME1L controls the early proliferative steps of adult neurogenesis. Glia 67, E511-E512.                               

Maria Leptin

• Ding, X., Willenborg, S., Kakanj, P., Leptin, M., and Eming, S. (2019). Metabolic control of epithelial-immune interactions in the skin. J Invest Dermatol139, S250-S250. DOI 10.1016/j.jid.2019.07.212.

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Roman-Ulrich Müller

• Braun F, Suarez V, Dinter J, Haneder S, Quaas A, Benzing T, Nierhoff D, Müller RU (2019). Successful use of TNFα blockade in a severe case of idiopathic non-granulomatous ulcerative jejunoileitis associated with thrombotic thrombocytopenic purpura. BMJ Open Gastroenterol. 2019 Feb 8;6(1):e000252. doi: 10.1136/bmjgast-2018-000252. eCollection 2019 
• Braun, F., and Muller, R.U. (2019). Urinary extracellular vesicles as a source of biomarkers reflecting renal cellular biology in human disease. Methods Cell Biol 154, 43-65. 10.1016/bs.mcb.2019.04.014.
• Esmaillie R, Ignarski M, Bohl K, Krüger T, Ahmad D, Seufert L, Schermer B, Benzing T, Müller RU, Fabretti F (2019). Activation of Hypoxia-Inducible Factor Signaling Modulates the RNA Protein Interactome in Caenorhabditis elegans. iScience (2019) 22, 466–476. doi.org/10.1016/j.isci.2019.11.039
• Ignarski M, Islam R, Müller RU (2019). Long Non-Coding RNAs in Kidney Disease. Int J Mol Sci. 2019 Jul 3;20(13). pii: E3276. doi: 10.3390/ijms20133276
• Ignarski M, Rill C, Kaiser RWJ, Kaldirim M, Neuhaus R, Esmaillie R, Li X, Klein C, Bohl K, Petersen M, Frese CK, Hoehne M, Atanassov I, Rinschen MM, Höpker K, Schermer B, Benzing T, Dietrich C, Fabretti F, Müller RU (2019). The RNA-protein interactome of differentiated kidney tubular epithelial cells. J Am Soc Nephrol. 2019 Apr;30(4):564-576. doi: 10.1681/ASN.2018090914. Epub 2019 Mar 13  
• Jain M, Kaiser RWJ, Bohl K, Hoehne M, Göbel H, Bartram MP, Habbig S, Müller RU, Fogo AB, Benzing T, Schermer B, Höpker K, Slaats GG (2019). Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis. Kidney Int. 2019 Apr;95(4):846-858. doi: 10.1016/j.kint.2018.10.034. Epub 2019 Feb 13
• Kaiser RWJ, Ignarski M, Van Nostrand EL, Frese CK, Jain M, Cukoski S, Heinen H, Schaechter M, Seufert L, Bunte K, Frommolt P, Keller P, Helm M, Bohl K, Höhne M, Schermer B, Benzing T, Höpker K, Dieterich C, Yeo GW, Müller RU, Fabretti F* (2019). A protein-RNA interaction atlas of the ribosome biogenesis factor AATF. Sci Rep. 2019 Jul 30;9(1):11071. doi: 10.1038/s41598-019-47552-3 (* shared last authorship)
• Rinschen MM, Müller RU (2019). A knowledge-guided kidney cell census-reconciling bulk omics with cellular heterogeneity? Kidney Int. 2019 Apr;95(4):733-735. doi: 10.1016/j.kint.2018.12.016 
• Schuldner, M., Dörsam, B., Shatnyeva, O., Reiners, K.S., Kubarenko, A., Hansen, H.P., Finkernagel, F., Roth, K., Theurich, S., Nist, A., Stiewe, T., Paschen, A., Knittel, G., Reinhardt, H.C., Müller, R., Hallek, M., and von Strandmann, E.P. (2019). Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53. Theranostics 9, 6047-6062. 10.7150/thno.36378.
• Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM* (2019). The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2019 Feb;95(2):333-349. doi: 10.1016/j.kint.2018.08.037. Epub 2018 Dec 3 (* shared last authorship)
• Völker LA, Burkert K, Scholten N, Grundmann F, Kurschat C, Benzing T, Hampl J, Becker JU, Müller RU. (2019). A case report of recurrent membranoproliferative glomerulonephritis after kidney transplantation due to ventriculoatrial shunt infection, BMC Nephrol. 2019 Aug 5;20(1):296. doi: 10.1186/s12882-019-1472-1   
• Wöstmann F, Müller RU, Göbel H, Benzing T, Becker JU, Bartram MP (2019). Case report: a peculiar glomerulopathy in a patient suffering from nephrotic syndrome. BMC Nephrol. 2019 Aug 22;20(1):326. doi: 10.1186/s12882-019-1478-8   

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Carien Niessen

• Bayliss, R.J., Wheeldon, J., Caucheteux, S., Niessen, C.M., and Piguet, V. (2019). 477 Identification of host cell factors involved HIV-1 trans-infection in dendritic cells. J Invest Dermatol 139, S82-S82.
• Clayton RW, Göbel K, Niessen CM, Paus R, van Steensel MAM, and Lim X. (2019) Homeostasis of the sebaceous gland and mechanisms of acne pathogenesis. Br J Dermatol. 2019 May 6. doi: 10.1111/bjd.17981. [Epub ahead of print]
• Ostermann AL, Wunderlich CM, Schneiders L, Vogt MC, Woeste MA, Belgardt BF, Niessen CM, Martiny B, Schauss AC, Frommolt P, Nikolaev A, Hövelmeyer N, Sears RC, Koch PJ, Günzel D, Brüning JC, Wunderlich FT (2019). Intestinal insulin/IGF1 signalling through FoxO1 regulates epithelial integrity and susceptibility to colon cancer. Nat Metab. 2019 Mar;1(3):371-389. doi: 10.1038/s42255-019-0037-8. Epub 2019 Mar 4. PMID: 32694718 
• Persa OD, Niessen CM (2019). Epithelial polarity limits EMT. Nat Cell Biol. 2019 Mar;21(3):299-300. doi: 10.1038/s41556-019-0284-7  
• Peters, F., Tellkamp, F., Brodesser, S., Wachsmuth, E., Tosetti, B., Karow, U., Bloch, W., Utermöhlen, O., Krönke, M., and Niessen, C.M. (2019). Epidermal barrier maintenance and morphogenesis are molecularly distinct and ceramide synthase 4 is a novel key player in epidermal barrier maintenance. J Invest Dermatol 139, S257-S257. DOI 10.1016/j.jid.2019.07.254.
• Ruebsam, M., Tellkamp, F., Nolte, H., Rinschen, M., Peskoller, M., Krueger, M., and Niessen, C.M. (2019). The atypical kinase C regulates epidermal adhesive junctions and the cytoskeleton essential for epidermal stratification. J Invest Dermatol 139, S314-S314.
• Wachsmuth, E., Awazawa, M., Aghdam, S., Akyüz, M., Bloch, W., Brüning, J.C., and Niessen, C.M. (2019). Skin insulin resistance impairs skin barrier function in hyperglycemic and diabetic mouse models. J Invest Dermatol139, S59-S59.

Peter Nürnberg

• Asif M, Kaygusuz E, Brancati F, Nienberg C, Nickelsen A, Jose J, Hochscherf J, Niefind K, Noegel AA, Nurnberg P, Hussain MS (2019). De novo mutation of CSNK2B encoding beta subunit of casein kinase 2 causes Filippi syndrome. Eur J Hum Genet. 27, 1504-1505
• Bustos BI, Perez-Palma E, Buch S, Azocar L, Riveras E, Ugarte GD, Toliat M, Nurnberg P, Lieb W, Franke A, Hinz S, Burmeister G, von Schonfels W, Schafmayer C, Volzke H, Volker U, Homuth G, Lerch MM, Santos JL, Puschel K, Bambs C, Roa JC, Gutierrez RA, Hampe J, De Ferrari GV, Miquel JF (2019). Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry. Sci Rep. 2019 Jan 28;9(1):772. doi: 10.1038/s41598-018-35852-z
• Coppola A, Cellini E, Stamberger H, Saarentaus E, Cetica V, Lal D, Djemie T, Bartnik-Glaska M, Ceulemans B, Cross JH, Deconinck T, De Masi S, Dorn T, Guerrini R, Hoffman-Zacharska D, Kooy F, Lagae L, Lench N, Lemke JR, Lucenteforte E, Madia F, Mefford HC, Morrogh D, Nuernberg P, Palotie A, Schoonjans AS, Striano P, Szczepanik E, Tostevin A, Vermeesch JR, Van Esch H, Van Paesschen W, Waters JJ, Weckhuysen S, Zara F, Jonghe PD, Sisodiya SM, Marini C, Lehesjioki AE, Craiu D, Talvik T, Caglayan H, Serratosa J, Sterbova K, Moller RS, Hjalgrim H, Lerche H, Weber Y, Helbig I, von Spiczak S, Barba C, Bogaerts A, Boni A, Galizia EC, Chiari S, Clementella C, Di Gacomo G, Ferrari A, Guarducci S, Giglio S, Holmgren P, Leu C, Mari F, Melani F, Novara F, Pantaleo M, Peeters E, Pisano T, Rosati A, Sander J, Schoeler N, Stankiewicz P, Striano S, Suls A, Traverso M, Vandeweyer G, Van Dijck A, Zuffardi O, Consortium ER, Consortium E (2019). Diagnostic implications of genetic copy number variation in epilepsy plus. Epilepsia. 2019 Apr;60(4):689-706. doi: 10.1111/epi.14683. Epub 2019 Mar 13        
• Cunha DL, Alakloby OM, Gruber R, Kakar N, Ahmad J. Alawbathani S, Plank R, Eckl K, Krabichler B, Altmuller J, Nurnberg P, Zschocke J, Borck G, Schmuth M, Alabdulkareem AS, Alnutaifi KA, Hennies HC (2019). Unknown mutations and genotype/phenotype correlations of autosomal recessive congenital ichthyosis in patients from Saudi Arabia and Pakistan. Mol Genet Genomic Med. 2019 Mar;7(3):e539. doi: 10.1002/mgg3.539. Epub 2019 Jan 1
• Dafsari HS, Kawalia A, Sprute R, Karakaya M, Malenica A, Herkenrath P, Nuernberg P, Motameny S, Thiele H, Cirak S (2019). Novel mutations in SLC6A5 with benign course in hyperekplexia. Cold Spring Harbor Molecular Case Stud. 2019 Dec; 5(6): a004465. doi: 10.1101/mcs.a004465  
• Dafsari HS, Sprute R, Wunderlich G, Daimaguler HS, Karaca E, Contreras A, Becker K, Schulze-Rhonhof M, Kiening K, Karakulak T, Kloss M, Horn A, Pauls A, Nurnberg P, Altmuller J, Thiele H, Assmann B, Koy A,  Cirak S (2019). Correction to: Novel mutations in KMT2B offer pathophysiological insights on childhood-onset progressive dystonia. J Hum Genet. 64, 1051–1054 (2019). doi.org/10.1038/s10038-019-0644-y   
• Dafsari HS, Sprute, R, Wunderlich G, Daimaguler HS, Karaca E, Contreras A, Becker K, Schulze-Rhonhof M, Kiening K, Karakulak T, Kloss M, Horn A, Pauls A, Nurnberg P, Altmuller J, Thiele H, Assmann B, Koy A, Cirak S (2019). Novel mutations in KMT2B offer pathophysiological insights into childhood-onset progressive dystonia. J Hum Genet. 2019 Aug;64(8):803-813. doi: 10.1038/s10038-019-0625-1. Epub 2019 Jun 5
• Diegmann S, Church J, Schnur R, Krusen M, Dreha-Kulaczewski S, Kuhn-Velten W, Wolf A, Huppke B, Millan F, Begtrup A, Almusafri F, Thiele H, Altmuller J, Nurnberg P, Muller M, Gartner J, Huppke P (2019). Inborn de novo mutations in NFE2L2 cause a multisystem disorder in children and adolescents: From gene identification to therapy development. Eur J Hum Genet. 2020 Feb; 28(2): 264–273.Published online 2019 Sep 4. doi: 10.1038/s41431-019-0501-7 
• Ding C, Scicluna BP, Stroo I. Yang J, Roelofs JJ, de Boer OJ, de Vos AF, Nurnberg P, Revenko AS, Crosby J, Van't Veer C, van der Poll T (2019). Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice. J Pathol. 2020 Jan; 250(1): 95–106. Published online 2019 Nov 25. doi: 10.1002/path.5354
• Du J, Sudarsanam M, Perez-Palma E, Ganna A, Francioli L, Iqbal S, Niestroj LM, Leu C, Weisburd B, Poterba T, Nurnberg P, Daly MJ, Palotie A, May P, Lal D (2019). Variant Score Ranker-a web application for intuitive missense variant prioritization. Bioinformatics. 2019 Nov 1;35(21):4478-4479. doi: 10.1093/bioinformatics/btz252      
• Forstner AJ, Maaser A, Strohmaier J, Ludwig KU, Degenhardt F, Streit F, Thiele H, Nurnberg P, Herms S, Hoffmann P, Cichon S, Rietschel M, Nothen MM (2019). Exome Sequencing of Multiply Affected Bipolar Disorder Families and Follow-up Resequencing Implicate Rare Variants in Neuronal Genes Contributing to Disease Etiology. Eur Neuropsychopharm. 29, S836-S837
• Gopel W, Muller M, Rabe H, Borgmann J, Rausch TK, Faust K, Kribs A, Dotsch J, Ellinghaus D, Hartel C, Roll C, Szabo M, Nurnberg P, Franke A, Konig IR, Turner MA, Herting E (2019). Genetic background of high blood pressure is associated with reduced mortality in premature neonates. Arch Dis Child Fetal Neonatal Ed. Published Online First: 14 June 2019. doi: 10.1136/archdischild-2019-317131
• Grassmann F, Harsch S, Brandl C, Kiel C, Nurnberg P, Toliat MR, Fleckenstein M, Pfau M, Schmitz-Valckenberg S, Holz FG, Chew EY, Swaroop A, Ratnapriya R, Klein ML, Mulyukov Z, Zamiri P, Weber BHF (2019). Assessment of Novel Genome-Wide Significant Gene Loci and Lesion Growth in Geographic Atrophy Secondary to Age-Related Macular Degeneration. JAMA Ophthalmol. 2019 May 23. doi: 10.1001/jamaophthalmol.2019.1318. [Epub ahead of print]  
• Hauke J, Hahnen E, Schneider S. Reuss A, Richters L, Kommoss S, Heimbach A, Marme F, Schmidt S, Prieske K, Gevensleben H, Burges A, Borde J, De Gregorio N, Nurnberg P, El-Balat A, Thiele H, Hilpert F, Altmuller J, Meier W, Dietrich D, Kimmig R, Schoemig-Markiefka B, Kast K, Braicu E, Baumann K, Jackisch C, Park-Simon TW, Ernst C, Hanker L, Pfisterer J, Schnelzer A, du Bois A, Schmutzler RK, Harter P (2019). Deleterious somatic variants in 473 consecutive individuals with ovarian cancer: results of the observational AGO-TR1 study (NCT02222883). J Med Genet. 2019 Sep;56(9):574-580. doi: 10.1136/jmedgenet-2018-105930. Epub 2019 Apr 12
• Huppke P, Wegener E, Gilley J, Angeletti C, Kurth I, Drenth JPH, Stadelmann C, Barrantes-Freer A, Bruck W, Thiele H, Nurnberg P, Gartner J, Orsomando G, Coleman MP (2019). Homozygous NMNAT2 mutation in sisters with polyneuropathy and erythromelalgia. Exp Neurol. 2019 Oct;320:112958. doi: 10.1016/j.expneurol.2019.112958. Epub 2019 May 24          
• Hussain MS, Baig SM, Moawia A, Shaheen R, Ewida N, Al-Owain M, Rasool S, Budde B, Hahn A, Noegel AA, Alkuraya FS, Nurnberg P (2019). Mutations of KIF14, encoding a kinesin-3 family member of microtubule motors, cause primary microcephaly. Eur J Hum Genet. 27, 301-302    
• Jurkute N, Leu C, Pogoda HM, Arno G, Robson AG, Nurnberg G, Altmuller J, Thiele H, Motameny S, Toliat MR, Powell K, Hohne W, Michaelides M, Webster AR, Moore AT, Hammerschmidt M, Nurnberg P, Yu-Wai-Man P, Votruba M (2019). SSBP1 mutations in dominant optic atrophy with variable retinal degeneration. Ann Neurol. 2019 Sep;86(3):368-383. doi: 10.1002/ana.25550. Epub 2019 Jul 31   
• Karakaya M, Storbeck M, Strathmann E, Delle Vedove A, Hoelker I, Altmueller J, Motameny S, Alawbathani S, Thiele H, Polat I, Wunderlich G, Ardicli D, Topaloglu H, Kirschner J, Schrank B, Maroofian R, Magnusson O, Yis U, Nuernberg P, Heller R, Wirth B (2019). Identification and characterization of disease-causing genes in non-5q-SMA by next-generation sequencing technology: Lessons learned from NeurOmics study. Eur J Hum Genet.  27, 1483-1484
• Karsak M, Glebov K, Scheffold M, Bajaj T, Kawalia A. Karaca I, Rading S, Kornhuber J, Peters O, Diez-Fairen M, Frolich L, Hull M, Wiltfang J, Scherer M, Riedel-Heller S, Schneider A, Heneka MT, Fliessbach K, Sharaf A, Thiele H, Lennarz M, Jessen F, Maier W, Kubisch C, Ignatova Z, Nurnberg P, Pastor P, Walter J, Ramirez A (2019). A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2. Hum Mutat. 2020 Jan;41(1):169-181. doi: 10.1002/humu.23904. Epub 2019 Sep 15
• Khan HN, Perlee D, Schoenmaker L, Van Der Meer AJ, Franitza M, Toliat MR, Nuernberg P, Zwinderman AH, van Der Poll T, Scicluna BP (2019). Leukocyte transcriptional signatures dependent on LPS dosage in human endotoxemia. J Leukoc Biol. 2019 Nov;106(5):1153-1160. doi: 10.1002/JLB.4A0219-050R. Epub 2019 Jul 7           
• Khayyat AIA, Baig SM, Abdullah U, Haq EU, Ali Z, Malik NA, Tariq M, Budde B, Noegel AA, Nurnberg P, Hussain MS (2019). Mutation in C1orf131, encoding a novel nucleolar protein, causes intellectual disability in a large Pakistani family. Eur J Hum Genet. 27, 1392-1393  
• Kinfe TM, Asif M, Chakravarthy KV, Deer TR, Kramer JM, Yearwood TL, Hurlemann R, Hussain MS, Motameny S, Wagle P, Nurnberg P, Gravius S, Randau T, Gravius N, Chaudhry SR, Muhammad S (2019). Unilateral L4-dorsal root ganglion stimulation evokes pain relief in chronic neuropathic postsurgical knee pain and changes of inflammatory markers: part II whole transcriptome profiling. J Transl Med. 2019 Jun 19;17(1):205. doi: 10.1186/s12967-019-1952-x   
• Lerche H, Berkovic SF, Lowenstein DH, May P, Wolking S, Musa MK, Lal D, Heyne HO, Bobbili DR, Perez-Palma E, Schubert J, Becker F, Thiele H, Altmuller J, Jabbari K, Ruppert AK, Jurkowski W, Striano P, Caglayan H, Yalcin D, Dizdarer G, Aslan K, Yapici Z, Kuscu D, Siren A, Moller RS, Hjalgrim H, Nikanorova M, Muhle H, Helbig I, Kunz W, Weber Y, Weckhuysen S, Jonghe P, Sisodiya S, Nabbout R, Balling R, Sander T, Koeleman BPC, Palotie A, Lehesjoki AE, Nothnagel M, Nurnberg P, Zara F, Krause R, Lerche H, Leu C, Peter S, Weber YG, Avbersek A, Heggeli K, Gambardella A, Langley SR, Krenn M, Klein KM, McCormack M, Borghei M, Willis J, Berghuis B, Jorgensen A, Auce P, Francis B, Srivastava P, Sonsma ACM, Sander JW, Zimprich F, Depondt C, Johnson MM, Marson AG, Sills GJ, Kunz WS, Cavalleri GL, Delanty N, Sisodiya SM, Heinzen EL, Petrovski S, Allen AS, Bellows ST, Berkovic SF, Bridgers J, Burgess R, Cavalleri G, Chung SK, Cossette P, Dlugos D, Epstein MP, Freyer C, Goldstein DB, Hildebrand MS, Johnson MR, Kuzniecky R, Lowenstein DH, Mayeux R, Mebane C, Mefford HC, O'Brien TJ, Ottman R, Petrou S, Pickrell WO, Poduri A, Radtke RA, Rees MI, Regan BM, Ren Z, Scheffer IE, Thomas RH, Wang Q, Consortium EC, Consortium E, Phenome EKCE (2019). Intestinal-Cell Kinase and Juvenile Myoclonic Epilepsy. N Engl J Med. 2019 Apr 18;380(16):e24. doi: 10.1056/NEJMc1805100  
• Liao DS, Grossi FV, El Mehdi D, Gerber MR, Brown DM, Heier JS, Wykoff CC, Singerman LJ, Abraham P, Grassmann F, Nuernberg P, Weber BHF, Deschatelets P, Kim RY, Chung CY, Ribeiro RM, Hamdani M, Rosenfeld PJ, Boyer DS, Slakter JS, Francois CG (2019). Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial. Ophthalmology. 2020 Feb;127(2):186-195. doi: 10.1016/j.ophtha.2019.07.011. Epub 2019 Jul 16  
• Lima Cunha D, Alakloby OM, Gruber R, Kakar N, Ahmad J, Alawbathani S, Plank R, Eckl K, Krabichler B, Altmuller J, Nurnberg P, Zschocke J, Borck G, Schmuth M, Alabdulkareem AS, Abdulaziz Alnutaifi K, Hennies HC (2019). Unknown mutations and genotype/phenotype correlations of autosomal recessive congenital ichthyosis in patients from Saudi Arabia and Pakistan. Mol Genet Genomic Med. 2019 Mar;7(3):e539. doi: 10.1002/mgg3.539. Epub 2019 Jan 1  
• Maaser A, Strohmaier J, Ludwig KU, Henschel L, Streit F, Degenhardt F, Sivalingam S, Schenk LM, Koller AC, Fischer SB, Thiele H, Nurnberg P, Parra JG, Diaz GO, Auburger G, Albus M, Borrmann-Hassenbach M, Gonzalez MJ, Flores SG, Fabeiro FJC, Noriega FD, Perez FP, Gonzalez JH, Rivas F, Mayoral F, Herms S, Hoffmann P, Cichon S, Rietschel M, Nothen MM, Forstner AJ (2019). Exome sequencing of multiplex bipolar disorder families and follow-up resequencing implicate rare variants in neuronal genes contributing to disease etiology. Eur J Hum Genet. 27, 261-262
• Mehrjoo Z, Fattahi Z, Beheshtian M, Mohseni M, Poustchi H, Ardalani F, Jalalvand K, Arzhangi S, Mohammadi Z, Khoshbakht S, Najafi F, Nikuei P, Haddadi M, Zohrehvand E, Oladnabi M, Mohammadzadeh A, Jafari MH, Akhtarkhavari T, Gooshki ES, Haghdoost A, Najafipour R, Niestroj LM, Helwing B, Gossmann Y, Toliat MR, Malekzadeh R, Nurnberg P, Kahrizi K, Najmabadi H, Nothnagel M (2019). Distinct genetic variation and heterogeneity of the Iranian population. PLoS Genet. 2019 Sep 24;15(9):e1008385. doi: 10.1371/journal.pgen.1008385. eCollection 2019 Sep  
• Moosa S, Yamamoto GL, Garbes L, Keupp K, Beleza-Meireles A, Moreno CA, Valadares ER, de Sousa SB, Maia S, Saraiva J, Honjo RS, Kim CA, Cabral de Menezes H, Lausch E, Lorini PV, Lamounier A, Jr., Carniero TCB, Giunta C, Rohrbach M, Janner M, Semler O, Beleggia F, Li Y, Yigit G, Reintjes N, Altmuller J, Nurnberg P, Cavalcanti DP, Zabel B, Warman ML, Bertola DR, Wollnik B, Netzer C (2019). Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta. Am J Hum Genet. 2019 Oct 3;105(4):836-843. doi: 10.1016/j.ajhg.2019.08.008. Epub 2019 Sep 26
• Niestroj LM, May P, Artomov M, Kobow K, Coras R, Perez-Palma E, Altmuller J, Thiele H, Nurnberg P, Leu C, Palotie A, Daly MJ, Klein KM, Beschorner R, Weber YG, Blumcke I, Lal D (2019). Assessment of genetic variant burden in epilepsy-associated brain lesions. Eur J Hum Genet. EJHG 27, 1738-1744 
• Ozieblo D, Sarosiak A, Leja ML, Budde BS, Tacikowska G, Di Donato N, Bolz HJ, Nurnberg P, Skarzynski H, Oldak M (2019). First confirmatory study on PTPRQ as an autosomal dominant non-syndromic hearing loss gene. J Transl Med. 2019 Oct 26;17(1):351. doi: 10.1186/s12967-019-2099-5
• Pauli S, Altmuller J, Schroder S, Ohlenbusch A, Dreha-Kulaczewski S, Bergmann C, Nurnberg P, Thiele H, Li Y, Wollnik B, Brockmann K (2019). Homozygosity for the c.428delG variant in KIAA0586 in a healthy individual: implications for molecular testing in patients with Joubert syndrome. J Med Genet. 2019 Apr;56(4):261-264. doi: 10.1136/jmedgenet-2018-105470. Epub 2018 Aug 17
• Perez-Palma E, Bustos BI, Lal D, Buch S, Azocar L, Toliat MR, Lieb W, Franke A, Hinz S, Burmeister G, von Shonfels W, Schafmayer C, Ahnert P, Volzke H, Volker U, Homuth G, Lerch MM, Puschel K, Gutierrez RA, Hampe J, Nurnberg P, Miquel JF, De Ferrari GV (2019). Copy number variants in lipid metabolism genes are associated with gallstones disease in men. Eur J Hum Genet. EJHG
• Perez-Palma E, Gramm M, Nurnberg P, May P, Lal D (2019). Simple ClinVar: an interactive web server to explore and retrieve gene and disease variants aggregated in ClinVar database. Nucleic Acids Res. 47, W99-W105
• Pergande M, Motameny S, Ozdemir O, Kreutzer M, Wang H, Daimaguler HS, Becker K, Karakaya M, Ehrhardt H, Elcioglu N, Ostojic S, Chao CM, Kawalia A, Duman O, Koy A, Hahn A, Reimann J, Schoner K, Schanzer A, Westhoff JH, Schwaibold EMC, Cossee M, Imbert-Bouteille M, von Pein H, Haliloglu G, Topaloglu H, Altmuller J, Nurnberg P, Thiele H, Heller R, Cirak S (2019). The genomic and clinical landscape of fetal akinesia. Genet Med. 2019 Nov 4. doi: 10.1038/s41436-019-0680-1. [Epub ahead of print]  
• Perlee D, de Vos AF, Scicluna BP, Mancheno P, de la Rosa O, Dalemans W, Nurnberg P, Lombardo E, van der Poll T (2019). Human Adipose-Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae. Stem Cells Transl Med. 2019 Aug;8(8):785-796. doi: 10.1002/sctm.18-0260. Epub 2019 Apr 29  
• Prasetyanti PR, Hooff SR van, van Herwaarden T, de Vries N, Kalloe K, Rodermond H, van Leersum R, de Jong JH, Franitza M, Nurnberg P, Todaro M, Stassi G, Medema JP (2019). Capturing colorectal cancer inter-tumor heterogeneity in patient-derived xenograft (PDX) models. Int J Cancer. 2019 Jan 15;144(2):366-371. doi: 10.1002/ijc.31767. Epub 2018 Oct 22. 
• Preising MN, Gorg B, Friedburg C, Qvartskhava N, Budde BS, Bonus M, Toliat MR, Pfleger C, Altmuller J, Herebian D, Beyer M, Zollner HJ, Wittsack HJ, Schaper J, Klee D, Zechner U, Nurnberg P, Schipper J, Schnitzler A, Gohlke H, Lorenz B, Haussinger D, Bolz HJ (2019). Biallelic mutation of human SLC6A6 encoding the taurine transporter TAUT is linked to early retinal degeneration. FASEB J. 2019 Oct;33(10):11507-11527. doi: 10.1096/fj.201900914RR. Epub 2019 Jul 25       
• Romano M, Tafazzoli A, Mattern M, Sivalingam S, Wolf S, Rupp A, Thiele H, Altmuller J, Nurnberg P, Ellwanger J, Gambon R, Baumer A, Kohlschmidt N, Metze D, Holdenrieder S, Paus R, Lutjohann D, Frank J, Geyer M, Bertolini M, Kokordelis P, Betz RC (2019). Bi-allelic mutations in LSS, encoding lanosterol synthase, cause autosomal-recessive hypotrichosis simplex. Eur J Hum Genet. 27, 1282-1283  
• Vidal EA, Moyano TC, Bustos BI, Perez-Palma E, Moraga C, Riveras E, Montecinos A, Azocar L, Soto DC, Vidal M, Di Genova A, Puschel K, Nurnberg P, Buch S, Hampe J, Allende ML, Cambiazo V, Gonzalez M, Hodar C, Montecino M, Munoz-Espinoza C, Orellana A, Reyes-Jara A, Travisany D, Vizoso P, Moraga M, Eyheramendy S, Maass A, De Ferrari GV, Miquel JF, Gutierrez RA (2019). Whole Genome Sequence, Variant Discovery and Annotation in Mapuche-Huilliche Native South Americans. Sci Rep. 2019 Feb 14;9(1):2132. doi: 10.1038/s41598-019-39391-z   
• Vogelmann S, Kleinheinz K, Altmuller J, Thiele H, Nurnberg P, Schlesner M, Klapper W, Bruggemann M, Siebert R, Wagener R, Oschlies I (2019). Genetic Characterization of two Variants of the primary cutaneous Follicle Center Lymphoma. J Dtsch Dermatol. Ges 17, 1-2  
• Wagener R, Seufert J, Raimondi F, Bens S, Kleinheinz K, Nagel I, Altmuller J, Thiele H, Hubschmann D, Kohler CW, Nurnberg P, Au-Yeung R, Burkhardt B, Horn H, Leoncini L, Jaffe ES, Ott G, Rymkiewicz G, Schlesner M, Russell RB, Klapper W, Siebert R (2019). The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma. Blood. 2019 Feb 28;133(9):962-966. doi: 10.1182/blood-2018-07-864025. Epub 2018 Dec 19   
• Weber-Lassalle N, Borde J, Weber-Lassalle K, Horváth J, Niederacher D, Arnold N, Kaulfuß S, Ernst C, Paul VG, Honisch E, Klaschik K, Volk AE, Kubisch C, Rapp S, Lichey N,  Altmüller J, Lepkes L, Pohl-Rescigno E, Thiele H, Nürnberg P, Larsen M, Richters L,  Rhiem K, Wappenschmidt B, Engel C, Meindl A, Schmutzler RK, Hahnen E, Hauke J (2020). Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer. Breast Cancer Res. 2019 Apr 29;21(1):55. doi: 10.1186/s13058-019-1137-9 
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Linda Partridge

• Augustin H, Zylbertal A, Partridge L (2019). A Computational Model of the Escape Response Latency in the Giant Fiber System of Drosophila melanogaster. eNeuro. 6, e0423-18.2019  
• Castillo-Quan JI, Tain LS, Kinghorn KJ, Li L, Grönke S, Hinze Y, Blackwell TK, Bjedov I, Partridge L (2019). A triple drug combination targeting components of the nutrient-sensing network maximizes longevity. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):20817-20819. doi: 10.1073/pnas.1913212116. Epub 2019 Sep 30
• Dönertaş HM, Fuentealba M, Partridge L, Thornton JM (2019). Identifying Potential Ageing-Modulating Drugs In Silico. Trends Endocrinol Metab. 2019 Feb;30(2):118-131. doi: 10.1016/j.tem.2018.11.005. Epub 2018 Dec 20. PMID: 30581056 Review.  
• Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019). Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol. 2019 Jan 9;15(1):e1006639. doi: 10.1371/journal.pcbi.1006639. eCollection 2019 Jan 
• Hahn O, Drews LF, Nguyen A, Tatsuta T, Gkioni L, Hendrich O, Zhang Q, Langer T, Pletcher S, Wakelam MJO, Beyer A, Grönke S, Partridge L (2019). A nutritional memory effect counteracts the benefits of dietary restriction in old mice. Nat Metab. 1059–1073 
• Moens TG, Niccoli T, Wilson KM, Atilano ML, Birsa N, Gittings LM, Holbling BV, Dyson MC, Thoeng A, Neeves J, Glaria I, Yu L, Bussmann J, Storkebaum E, Pardo M, Choudhary JS, Fratt, P, Partridge L, Isaacs AM (2019). C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A. Acta Neuropathol. 2019 Mar;137(3):487-500. doi: 10.1007/s00401-018-1946-4. Epub 2019 Jan 2  
• Morón-Oset J, Supèr T, Esser J, Isaacs AM, Grönke S, Partridge L (2019). Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain. Acta Neuropathol Commun. 2019 Dec 16;7(1):209. doi: 10.1186/s40478-019-0860-x. PMID: 31843021
• Solon-Biet SM, Cogger VC, Pulpitel T, Wahl D, Clark X, Bagley E, Gregoriou GC, Senior AM, Wang QP, Brandon AE, Perks R, O'Sullivan J, Koay YC, Bell-Anderson K, Kebede M, Yau B, Atkinson C, Svineng G, Dodgson T, Wali JA, Piper MDW, Juricic P, Partridge L, Rose AJ, Raubenheimer D, Cooney GJ, Le Couteur DG, Simpson SJ  (2019). Branched chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control. Nat Metab. 2019 May;1(5):532-545. doi: 10.1038/s42255-019-0059-2. Epub 2019 Apr 29
• Weigelt CM, Hahn O, Arlt K, Gruhn M, Jahn AJ, Esser J, Werner JA, Klein C, Buschges A, Gronke S, Partridge L (2019). Loss of miR-210 leads to progressive retinal degeneration in Drosophila melanogaster. Life Sci Alliance. 2019 Jan 22;2(1). pii: e201800149. doi: 10.26508/lsa.201800149. Print 2019 Feb
• Yamada SB, Gendron TF, Niccoli T, Genuth NR, Grosely R, Shi Y, Glaria I, Kramer NJ, Nakayama L, Fang S, Dinger TJI, Thoeng A, Rocha G, Barna M, Puglisi JD, Partridge L, Ichida JK, Isaacs AM, Petrucelli L, Gitler AD (2019). RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats. Nat Neurosci. 2019 Sep;22(9):1383-1388. doi: 10.1038/s41593-019-0455-7. Epub 2019 Jul 29              

Manolis Pasparakis  

• Eftychi C, Schwarzer R, Vlantis K, Wachsmuth L, Basic M, Wagle P, Neurath MF, Becker C, Bleich A, Pasparakis M. (2019). Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment. Immunity. 2019 Aug 20;51(2):367-380.e4. doi: 10.1016/j.immuni.2019.06.008. Epub 2019 Jul 23
• Fritsch M, Günther SD, Schwarzer R, Albert MC, Schorn F, Werthenbach JP, Schiffmann LM, Stair N, Stocks H, Seeger JM, Lamkanfi M, Krönke M, Pasparakis M, Kashkar H (2019). Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. Nature. 2019 Nov;575(7784):683-687. doi: 10.1038/s41586-019-1770-6. Epub 2019 Nov 20      
• Gräb J, Suárez I, van Gumpel E, Winter S, Schreiber F, Esser A, Hölscher C, Fritsch M, Herb M, Schramm M, Wachsmuth L, Pallasch C, Pasparakis M, Kashkar H, Rybniker J (2019). Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition. Nat Commun. 2019 Feb 8;10(1):688. doi: 10.1038/s41467-019-08405-9
• Koliaraki V, Chalkidi N, Henriques A, Tzaferis C, Polykratis A, Waisman A, Muller W, Hackam DJ, Pasparakis M, Kollias G (2019). Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis. Cell Rep. 2019 Jan 15;26(3):536-545.e4. doi: 10.1016/j.celrep.2018.12.072    
• Kondylis V, Pasparakis M (2019). RIP Kinases in Liver Cell Death, Inflammation and Cancer. Trends Mol Med. 2019 Jan;25(1):47-63. doi: 10.1016/j.molmed.2018.10.007. Epub 2018 Nov 16   
• Krishna-Subramanian S, Singer S, Armaka M, Banales JM, Holzer K, Schirmacher P, Walczak H, Kollias G, Pasparakis M, Kondylis V (2019). RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ. 2019 Apr 15. doi: 10.1038/s41418-019-0330-9. [Epub ahead of print] 
• Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand AJ, Robertson D, Feltham R, Anderton H, Darding M, Peltzer N, Dannappel M, Schünke H, Fava LL, Haschka MD, Glatter T, Nesvizhskii A, Schmidt A, Harris PA, Bertin J, Gough PJ, Villunger A, Silke J, Pasparakis M, Bianchi K, Meier P (2019). RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol Cell. 2019 Feb 7;73(3):413-428.e7. doi: 10.1016/j.molcel.2018.11.010. Epub 2018 Dec 28  
• MacVicar T, Ohba Y, Nolte H, Mayer FC, Tatsuta T, Sprenger HG, Lindner B, Zhao Y, Li J, Bruns C, Krüger M, Habich M, Riemer J, Schwarzer R, Pasparakis M, Henschke S, Brüning JC, Zamboni N, Langer T (2019). Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature. 2019 Nov;575(7782):361-365. doi: 10.1038/s41586-019-1738-6. Epub 2019 Nov 6  
• Polykratis A, Martens A, Eren RO, Shirasaki Y, Yamagishi M, Yamaguchi Y, Uemura S, Miura M, Holzmann B, Kollias G, Armaka M, van Loo G, Pasparakis M. (2019). A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain. Nat Cell Biol. 2019 Jun;21(6):731-742. doi: 10.1038/s41556-019-0324-3.  
• Priem D, Devos M, Druwé S, Martens A, Slowicka K, Ting AT, Pasparakis M, Declerq W, Vandenabeele P, van Loo G, Bertrand MJM (2019). A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms. Cell Death Dis. 2019 Sep 18;10(10):692. doi: 10.1038/s41419-019-1937-y         
• Torgovnick A, Heger JM, Liaki V, Isensee J, Schmitt A, Knittel G, Riabinska A, Beleggia F, Laurien L, Leeser U, Jüngst C, Siedek F, Vogel W, Klümper N, Nolte H, Wittersheim M, Tharun L, Castiglione R, Krüger M, Schauss A, Perner S, Pasparakis M, Büttner R, Persigehl T, Hucho T, Herter-Sprie GS, Schumacher B, Reinhardt HC (2019). The Cdkn1a^SUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression. Cell Rep.2018 Oct 23;25(4):1027-1039.e6. doi: 10.1016/j.celrep.2018.09.079       

Maria de las Nieves Peltzer  

• Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand AJ, Robertson D, Feltham R, Anderton H, Darding M, Peltzer N, Dannappel M, Schünke H, Fava LL, Haschka MD, Glatter T, Nesvizhskii A, Schmidt A, Harris PA, Bertin J, Gough PJ, Villunger A, Silke J, Pasparakis M, Bianchi K, Meier P, RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol Cell. 2019 Feb 7;73(3):413-428.e7. doi: 10.1016/j.molcel.2018.11.010. Epub 2018 Dec 28.PMID: 30598363 
• Peltzer N, Walczak H (2019). Cell Death and Inflammation - A Vital but Dangerous Liaison. Trends Immunol. 2019 May;40(5):387-402. doi: 10.1016/j.it.2019.03.006. Epub 2019 Apr 16
• Peltzer N, Walczak H. Endothelial Cell Killing by TAK1 Inhibition: A Novel Anti-angiogenic Strategy in Cancer Therapy. Dev Cell. 2019 Jan 28;48(2):127-128. doi: 10.1016/j.devcel.2019.01.011.PMID: 30695692 

Lena Pernas   

• Pernas L (2019). mSphere of Influence: Finding a Direction-How Do Mitochondria Know Where To Go? mSphere. 2019 Jul 3;4(4). pii: e00321-19. doi: 10.1128/mSphere.00321-19

Christina Polidori

• Gerger, P., Pai, R.K., Stuckenschneider, T., Falkenreck, J., Weigert, H., Stahl, W., Weber, B., Nelles, G., Spazzafumo, L., Schneider, S., and Polidori, M.C. (2019). Associations of Lipophilic Micronutrients with Physical and Cognitive Fitness in Persons with Mild Cognitive Impairment. Nutrients 11. 10.3390/nu11040902.
• Meyer, A.M., Becker, I., Siri, G., Brinkkotter, P.T., Benzing, T., Pilotto, A., and Polidori, M.C. (2019). New associations of the Multidimensional Prognostic Index. Z Gerontol Geriatr 52, 460-467. 10.1007/s00391-018-01471-6.
• Meyer, AM, Siri G, Becker I, Betz T, Bödecker AW, Robertz JW, Krause O, Benzing T, Pilotto A, Polidori MC (2019). The Multidimensional Prognostic Index in Clinical Practice: One-year follow-up study. Int J Clin Pract.2019 Aug 13:e13403 
• Pilotto A, Veronese N, Daragjati J, Cruz-Jentoft AJ, Polidori MC, Mattace-Raso F, Paccalin M, Topinkova E, Greco A, Mangoni A, Maggi S, Ferrucci L on behalf of the MPI_Age Investigators (2019). Using Multidimensional Prognostic Index to evaluate clinical outcomes of hospitalized older subjects: a prospective, multicenter, international study. J Gerontol A Biol Sci Med Sci. 2019; 74:1643-1649 
• von Arnim, C.A.F., Bartsch, T., Jacobs, A.H., Holbrook, J., Bergmann, P., Zieschang, T., Polidori, M.C., and Dodel, R. (2019). Diagnosis and treatment of cognitive impairment. Z Gerontol Geriatr 52, 309-315. 10.1007/s00391-019-01560-0.
• von Storch, K., Graaf, E., Wunderlich, M., Rietz, C., Polidori, M.C., and Woopen, C. (2019). Telemedicine-Assisted Self-Management Program for Type 2 Diabetes Patients. Diabetes Technol Ther 21, 514-521. 10.1089/dia.2019.0056.

Simon Pöpsel 

• Kasinath V, Poepsel S, Nogales, E (2019). Recent Structural Insights into Polycomb Repressive Complex 2 Regulation and Substrate Binding. Biochemistry.2019 Feb 5;58(5):346-354. doi: 10.1021/acs.biochem.8b01064. Epub 2018 Dec 3  

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Alvaro Rada-Iglesias

• Bleckwehl T, Rada-Iglesias A (2019). Transcriptional and epigenetic control of germline competence and specification. Curr Opin Cell Biol. 2019 Dec;61:1-8. doi: 10.1016/j.ceb.2019.05.006. Epub 2019 Jun 21
• Frank S, Ahuja G, Bartsch D, Russ N, Yao W, Kuo JC, Derks JP, Akhade VS, Kargapolova Y, Georgomanolis T, Messling JE, Gramm M, Brant L, Rehimi R, Vargas NE, Kuroczik A, Yang TP, Sahito RGA, Franzen J, Hescheler J, Sachinidis A, Peifer M, Rada-Iglesias A, Kanduri M, Costa IG, Kanduri C, Papantonis A, Kurian L (2019). yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs. Cell Stem Cell. 2018 Nov 21. pii: S1934-5909(18)30541-1. doi: 10.1016/j.stem.2018.11.005. PMID: 30554961
• Hollstein, R., Stüssel, L.G., Laugsch, M., Haeberlein, F., Hochfeld, L.M., Welzenbach, J., Schröder, J., Thieme, F., Heimbach, A., Hess, T., Gehlen, J., Heilmann-Heimbach, S., Mangold, E., Rada-Iglesias, A., Odermatt, B., and Ludwig, K.U. (2019). Identification and characterization of microRNA-149, a candidate for orofacial clefting. Eur J Hum Genet 27, 1288-1288.
• Ishorst, N., Henschel, L., Thieme, F., Drichel, D., Sivalingam, S., Mehrem, S.L., Fechtner, A.C., Fazaal, J., Welzenbach, J., Heimbach, A., Maj, C., Hausen, J., Raff, R., Hoischen, A., Dixon, M., Rada-Iglesias, A., Bartusel, M., Rojas-Martinez, A., Aldhorae, K., Braumann, B., Kruse, T., Kirschneck, C., Reutter, H., Nowak, S., Gölz, L., Knapp, M., Krawitz, P., Nöthen, M.M., Nothnagel, M., Becker, T., Ludwig, K.U., and Mangold, E. (2019). Whole-exome sequencing and large-scale re-sequencing in nonsyndromic cleft lip with/without cleft palate identify novel susceptibility genes. Eur J Hum Genet 27, 1289-1290.
• Laugsch M, Bartusel M, Rehimi R, Alirzayeva H, Karaolidou A, Crispatzu G, Zentis P, Nikolic M, Bleckwehl T, Kolovos P, van Ijcken WFJ, Šarić T, Köhler K, Frommolt P, Lachlan K, Baptista J, Rada-Iglesias, A (2019). Modelling the pathological long-range regulatory effects of human structural variation with patient-specific hiPSCs. Cell Stem Cell. 2019 May 2;24(5):736-752.e12. doi: 10.1016/j.stem.2019.03.004. Epub 2019 Apr 11   
• Laugsch, M., Bartsuel, M., Rehimi, R., Alirzayeva, H., Karaolidou, A., Crispatzu, G., Zentis, P., Nikolic, M., Bleckwehl, T., Kolovos, P., van Ijcken, W.F.J., Saric, T., Koehler, K., Frommolt, P., Schaaf, C., Lachlan, K., Baptista, J., and Rada-Iglesias, A. (2019). Modeling the pathological long-range regulatory effects of human structural variation with patient-specific hiPSCs. Eur J Hum Genet 27, 1168-1169.
• Matheus, F., Rusha, E., Rehimi, R., Molitor, L., Pertek, A., Modic, M., Feederle, R., Flatley, A., Kremmer, E., Geerlof, A., Rishko, V., Rada-Iglesias, A., and Drukker, M. (2019). Pathological ASXL1 Mutations and Protein Variants Impair Neural Crest Development. Stem Cell Reports 12, 861-868. 10.1016/j.stemcr.2019.03.006.
• Pachano T, Crispatzu G, Rada-Iglesias A (2019). Polycomb proteins as organizers of 3D genome architecture in embryonic stem cells. Brief Funct Genomics. 2019 Nov 19;18(6):358-366. doi: 10.1093/bfgp/elz022
• Stuessel, L.G., Hochfeld, L.M., Schroeder, J., Thieme, F., Hess, T., Gehlen, J., Heilmann-Heimbach, S., Knapp, M., Mangold, E., Rada-Iglesias, A., and Ludwig, K.U. (2019). MicroRNA profiling in human neural crest cells and integration of GWAS data suggest involvement of miRNA149 in craniofacial disease. Eur J Hum Genet 27, 111-111.
• Welzenbach, J., Hammond, N., Bartusel, M., Mangold, E., Rada-Iglesias, A., Dixon, M.J., Knapp, M., and Ludwig, K.U. (2019). Systematic integration of genetic and epigenetic data yields novel insights into craniofacial development and orofacial clefting. Eur J Hum Genet 27, 1711-1711.
• Zanella M, Vitriolo A, Andirko A, Martins PT, Sturm S, O'Rourke T, Laugsch M, Malerba N, Skaros A, Trattaro S, Germain PL, Mihailovic M, Merla G, Rada-Iglesias A, Boeckx C, Testa G (2019). Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication. Sci Adv. 2019 Dec 4;5(12):eaaw7908. doi: 10.1126/sciadv.aaw7908. eCollection 2019 Dec 

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Hans Christian Reinhardt

• Castiglione R, Alidousty C, Holz B, Wagener S, Baar T, Heydt C, Binot E, Zupp S, Kron A, Wolf J, Merkelbach-Bruse S, Reinhardt HC, Büttner R, Schultheis AM (2019). Comparison of the genomic background of MET-altered carcinomas of the lung: biological differences and analogies. Mod Pathol. 2019 May;32(5):627-638. doi: 10.1038/s41379-018-0182-8. Epub 2018 Nov 20
• Dammert MA, Brägelmann J, Olsen RR, Böhm S, Monhasery N, Whitney CP, Chalishazar MD, Tumbrink HL, Guthrie MR, Klein S, Ireland AS, Ryan J, Schmitt A, Marx A, Ozretić L, Castiglione R, Lorenz C, Jachimowicz RD, Wolf E, Thomas RK, Poirier JT, Büttner R, Sen T, Byers LA, Reinhardt HC, Letai A, Oliver TG, Sos ML (2019). MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer. Nat Commun. 2019 Aug 2;10(1):3485. doi: 10.1038/s41467-019-11371-x. PMID: 31375684 
• Erber J, Steiner JD, Isensee J, Lobbes LA, Toschka A, Beleggia F, Schmitt A, Kaiser RWJ, Siedek F, Persigehl T, Hucho T, Reinhardt HC (2019). Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells. Cancer Res. 2019 Oct 1;79(19):4855-4868. doi: 10.1158/0008-5472.CAN-18-3959. Epub 2019 Aug 12. PMID: 31405847  
• Grimm C, Fischer A, Farrelly AM, Kalachand R, Castiglione R, Wasserburger E, Hussong M, Schultheis A, Altmüller J, Thiele H, Reinhardt HC, Hauschulz K, Hennessy BT, Herwig R, Lienhard M, Büttner R, Schweiger MR (2019). Combined targeted re-sequencing of cytosine DNA methylations and mutations for the determination of PARP1 inhibitor sensitivity. J Mol Diagn. 2019 Mar;21(2):198-213. doi: 10.1016/j.jmoldx.2018.10.007. Epub 2018 Dec 19 
• Jachimowicz RD, Beleggia F, Isensee J, Velpula BB, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y (2019). UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3. PMID: 30612738 
• Jachimowicz RD, Bhavana VB, Beleggia F, Isensee J, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y (2019). UBQLN4 regulates double-strand break repair by repressing homologous recombination and is overexpressed in aggressive tumors. Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3
• Jachimowicz RD, Goergens J, Reinhardt HC (2019). DNA double-strand break repair pathway choice - from basic biology to clinical exploitation. Cell Cycle. 2019 Jul;18(13):1423-1434. doi: 10.1080/15384101.2019.1618542. Epub 2019 May 22. PMID: 31116084 
• Jachimowicz RD, Reinhardt HC (2019). UBQLN4 promotes non-homologous end joining by repressing DNA end-resection. Mol Cell Oncol. 2019 Feb 20;6(2):1575692. doi: 10.1080/23723556.2019.1575692. eCollection 2019. PMID: 31131301     
• Puppe J, Opdam M, Schouten PC, Jóźwiak K, Lips E, Severson T, van de Ven M, Brambillasca C, Bouwman P, van Tellingen O, Bernards R, Wesseling J, Eichler C, Thangarajah F, Malter W, Pandey GK, Ozretić L, Caldas C, van Lohuizen M, Hauptmann M, Rhiem K, Hahnen E, Reinhardt HC, Büttner R, Mallmann P, Schömig-Markiefka B, Schmutzler R, Linn S, Jonkers J (2019). EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy. Clin Cancer Res. 2019 Jul 15;25(14):4351-4362. doi: 10.1158/1078-0432.CCR-18-4024. Epub 2019 Apr 29. PMID: 31036541
• Schuldner M, Dörsam B, Shatnyeva O, Reiners KS, Kubarenko A, Hansen HP, Finkernagel F, Roth K, Theurich S, Nist A, Stiewe T, Paschen A, Knittel G, Reinhardt HC, Müller R, Hallek M, von Strandmann EP (2019). Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53. Theranostics. 2019 Aug 14;9(21):6047-6062. doi: 10.7150/thno.36378. eCollection 2019. PMID: 31534536  

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Jan Riemer  

• Anton V, Buntenbroich I, Schuster R, Babatz F, Simões T, Altin S, Calabrese G, Riemer J, Schauss A, Escobar-Henriques M (2019). Plasticity in salt-bridge allows fusion-competent ubiquitylation of mitofusins and Cdc48 recognition. Life Sci Alliance. 2019 Nov 18;2(6). pii: e201900491. doi: 10.26508/lsa.201900491. Print 2019 Dec  
• Calabrese G, Peker E, Amponsah PS, Hoehne MN, Riemer T, Mai M, Bienert GP, Deponte M, Morgan B, Riemer J (2019). Hyperoxidation of mitochondrial peroxiredoxin limits H₂ O₂ -induced cell death in yeast. EMBO J. 2019 Sep 16;38(18):e101552. doi: 10.15252/embj.2019101552. Epub 2019 Aug 7
• Habich M, Salscheider S, Murschall L, Hoehne M, Fischer M, Schorn F, Petrungaro C, Ali M, Erdogan A, Abou-Eid S, Kashkar H, Dengjel J, Riemer J (2019). Vectorial import via a metastable disulfide-linked complex allows for a quality control step and efficient import by the mitochondrial disulfide relay. Cell Rep. 2019 Jan 15;26(3):759-774.e5. doi: 10.1016/j.celrep.2018.12.092  
• MacVicar T, Ohba Y, Nolte H, Mayer FC, Tatsuta T, Sprenger HG, Lindner B, Zhao Y, Li J, Bruns C, Krüger M, Habich M, Riemer J, Schwarzer R, Pasparakis M, Henschke S, Brüning JC, Zamboni N, Langer T (2019). Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature. 2019 Nov;575(7782):361-365. doi: 10.1038/s41586-019-1738-6. Epub 2019 Nov 6 

Elena Rugarli

• Iershov A, Nemazanyy I, Alkhoury C, Girard M, Barth E, Cagnard N, Montagner A, Chretien D, Rugarli EI, Guillou H, Pende M, Panasyuk G (2019). The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα. Nat Commun. 2019 Apr 5;10(1):1566. doi: 10.1038/s41467-019-09598-9. PMID: 30952952
• Murru S, Hess S, Barth E, Almajan ER, Schatton D, Hermans S, Brodesser S, Langer T, Kloppenburg P, Rugarli EI (2019). Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019 Aug;67(8):1526-1541. doi: 10.1002/glia.23626. Epub 2019 Apr 16
• Rugarli, E. (2019). Post-transcriptional regulation of mitochondrial function. Febs Open Bio 9, 17-17.
• Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola A, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2019) Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med. 11, pii: e9288. doi 10.15252/emmm. 201809288

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Björn Schumacher

• Bayersdorf R, Schumacher B (2019). Recent advances in understanding the mechanisms determining longevity. F1000Res. 2019 Aug 9;8. pii: F1000 Faculty Rev-1403. doi: 10.12688/f1000research.19610.1. eCollection 2019 
• Böhmer, A.C., Schröder, J., Schüller, V., Becker, J., Hess, T., May, A., Gerges, C., Kreuser, N., Schmidt, T., Veits, L., Fuchs, C., Izbicki, J.R., Schumacher, B., Vieth, M., Neuhaus, H., Rösch, T., Ell, C., Nöthen, M.M., Gockel, I., and Schumacher, J. (2019). Barrett's esophagus - functional annotation of genetic associations using tissue-specific gene expression and the FUMA platform. Eur J Hum Genet 27, 1731-1732.
• da Silva PFL, Schumacher B (2019). DNA damage responses in ageing. Open Biol. 2019 Nov 29;9(11):190168. doi: 10.1098/rsob.190168. Epub 2019 Nov 20.
• Doll MA, Soltanmohammadi N, Schumacher B (2019). ALG-2/AGO-Dependent mir-35 Family Regulates DNA Damage-Induced Apoptosis Through MPK-1/ERK MAPK Signaling Downstreamof the Core Apoptotic Machinery in Caenorhabditis elegans. Genetics. 2019 Jul 11. pii: genetics.302458.2019. doi: 10.1534/genetics.119.302458.
• Dong, J., Gharahkhani, P., Chow, W.H., Gammon, M.D., Liu, G., Caldas, C., Wu, A.H., Ye, W.M., Onstad, L., Anderson, L.A., Bernstein, L., Pharoah, P.D., Risch, H.A., Corley, D.A., Fitzgerald, R.C., Iyer, P.G., Reid, B.J., Lagergren, J., Shaheen, N.J., Vaughan, T.L., MacGregor, S., Love, S., Palles, C., Tomlinson, I., Gockel, I., May, A., Gerges, C., Anders, M., Böhmer, A.C., Becker, J., Kreuser, N., Thieme, R., Noder, T., Venerito, M., Veits, L., Schmidt, T., Schmidt, C., Izbicki, J.R., Hölscher, A.H., Lang, H.K., Lorenz, D., Schumacher, B., Mayershofer, R., Vashist, Y., Ott, K., Vieth, M., Weismüller, J., Nöthen, M.M., Moebus, S., Knapp, M., Peters, W.H.M., Neuhaus, H., Rösch, T., Ell, C., Jankowski, J., Schumacher, J., Neale, R.E., Whiteman, D.C., Thrift, A.P., and Study, S.E.C. (2019). No Association Between Vitamin D Status and Risk of Barrett's Esophagus or Esophageal Adenocarcinoma: A Mendelian Randomization Study. Clin Gastroenterol H 17, 2227-+. 10.1016/j.cgh.2019.01.041.
• Habermehl, T.L., Parkinson, K.C., Hubbard, G.B., Ikeno, Y., Engelmeyer, J.I., Schumacher, B., and Mason, J.B. (2019). Extension of longevity and reduction of inflammation is ovarian-dependent, but germ cell-independent in post-reproductive female mice. Geroscience 41, 25-38. 10.1007/s11357-018-0049-4.
• Jachimowicz RD, Bhavana VB, Beleggia F, Isensee J, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y (2019). UBQLN4 regulates double-strand break repair by repressing homologous recombination and is overexpressed in aggressive tumors, Cell. 2019 Jan 24;176(3):505-519.e22. doi: 10.1016/j.cell.2018.11.024. Epub 2019 Jan 3
• Notara, M., Behoudifard, S., Schumacher, B., and Cursiefen, C. (2019). UV light-blocking contact lenses prevent UVB-induced DNA and oxidative damage of the limbal stem cell niche, protect against inflammation and maintain putative stem cell phenotype. Invest Ophth Vis Sci 60.
• Ou HL, Kim CS, Uszkoreit S, Wickström SA, Schumacher B (2019). Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells. Dev Cell. 2019 Jul 22;50(2):167-183.e8. doi: 10.1016/j.devcel.2019.06.012 
• Rive C, Reina G, Wagle P, Treossi E, Palermo V, Bianco A, Gemma-Delogu L, Rieckher M, Schumacher B(2019). Improved Biocompatibility of Amino-functionalized Graphene Oxide in Caenorhabditis elegans. Small.2019 Nov;15(45):e1902699. doi: 10.1002/smll.201902699. Epub 2019 Oct 1
• Schröder, J., Schüller, V., May, A., Gerges, C., Anders, M., Becker, J., Hess, T., Kreuser, N., Noder, T., Venerito, M., Veits, L., Schmidt, T., Fuchs, C., Izbicki, J.R., Hölscher, A.H., Dakkak, D., Jansen-Winkeln, B., Moulla, Y., Lyros, O., Niebisch, S., Mehdorn, M., Lang, H., Lorenz, D., Schumacher, B., Mayershofer, R., Vashist, Y., Ott, K., Vieth, M., Weismüller, J., Mangold, E., Moebus, S., Knapp, M., Neuhaus, H., Rösch, T., Ell, C., Nöthen, M.M., Gockel, I., Thieme, R., Schumacher, J., and Böhmer, A.C. (2019). Statistical finemapping and functional annotation of risk loci for Barrett's esophagus and esophageal adenocarcinoma. Eur J Hum Genet 27, 1725-1726.
• Schröder, J., Schüller, V., May, A., Gerges, C., Anders, M., Becker, J., Hess, T., Kreuser, N., Thieme, R., Ludwig, K.U., Noder, T., Venerito, M., Veits, L., Schmidt, T., Fuchs, C., Izbicki, J.R., Hölscher, A.H., Dakkak, D., Jansen-Winkeln, B., Moulla, Y., Lyros, O., Niebisch, S., Mehdorn, M., Lang, H., Lorenz, D., Schumacher, B., Mayershofer, R., Vashist, Y., Ott, K., Vieth, M., Weismüller, J., Mangold, E., Nöthen, M.M., Moebus, S., Knapp, M., Neuhaus, H., Rösch, T., Ell, C., Gockel, I., Schumacher, J., and Böhmer, A.C. (2019). Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relevant tissues with genetic association data. Plos One 14. ARTN e0227072. 10.1371/journal.pone.0227072.
• Schumacher B, Vijg J (2019). Age is in the nucleus. Nat Metab. 2019. doi: 10.1038/s42255-019-0125-9. Epub 2019 Oct 7   
• Williams AB, Heider F, Messling JE, Riekher M, Bloch W, Schumacher B (2019). Restoration of Proteostasis in the Endoplasmic Reticulum Reverses an Inflammation-Like Response to Cytoplasmic DNA in Caenorhabditis elegans. Genetics. 2019 Aug;212(4):1259-1278. doi: 10.1534/genetics.119.302422. Epub 2019 Jun 27 

Eline Slagboom

• Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium (2019). Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology. 2019 Jan 16. pii: 10.1212/WNL.0000000000006851. doi: 10.1212/WNL.0000000000006851. [Epub ahead of print]
• Davies, G., Lam, M., Harris, S.E., Trampush, J.W., Luciano, M., Hill, W.D., Hagenaars, S.P., Ritchie, S.J., Marioni, R.E., Fawns-Ritchie, C., Liewald, D.C.M., Okely, J.A., Ahola-Olli, A.V., Barnes, C.L.K., Bertram, L., Bis, J.C., Burdick, K.E., Christoforou, A., DeRosse, P., Djurovic, S., Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D.E., Hayward, C., Hofer, E., Ikram, M.A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K.A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C.A., Sargurupremraj, M., Scholz, M., Smith, J.A., Smith, A.V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S.J., Ware, E.B., Windham, B.G., Wright, M.J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O.A., Armstrong, N.J., Assareh, A.A., Attia, J.R., Attix, D., Avramopoulos, D., Bennett, D.A., Bohmer, A.C., Boyle, P.A., Brodaty, H., Campbell, H., Cannon, T.D., Cirulli, E.T., Congdon, E., Conley, E.D., Corley, J., Cox, S.R., Dale, A.M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J.G., Evangelou, E., Faul, J.D., Ford, I., Freimer, N.A., Gao, H., Giegling, I., Gillespie, N.A., Gordon, S.D., Gottesman, R.F., Griswold, M.E., Gudnason, V., Harris, T.B., Hartmann, A.M., Hatzimanolis, A., Heiss, G., Holliday, E.G., Joshi, P.K., Kahonen, M., Kardia, S.L.R., Karlsson, I., Kleineidam, L., Knopman, D.S., Kochan, N.A., Konte, B., Kwok, J.B., Le Hellard, S., Lee, T., Lehtimaki, T., Li, S.C., Lill, C.M., Liu, T., Koini, M., London, E., Longstreth, W.T., Jr., Lopez, O.L., Loukola, A., Luck, T., Lundervold, A.J., Lundquist, A., Lyytikainen, L.P., Martin, N.G., Montgomery, G.W., Murray, A.D., Need, A.C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R.A., Psaty, B.M., Reppermund, S., Riedel-Heller, S.G., Rose, R.J., Rotter, J.I., Roussos, P., Rovio, S.P., Saba, Y., Sabb, F.W., Sachdev, P.S., Satizabal, C.L., Schmid, M., Scott, R.J., Scult, M.A., Simino, J., Slagboom, P.E., Smyrnis, N., Soumare, A., Stefanis, N.C., Stott, D.J., Straub, R.E., Sundet, K., Taylor, A.M., Taylor, K.D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A.N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K.H., Widen, E., Yang, Q., Zhao, W., Adams, H.H.H., Arking, D.E., Bilder, R.M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P.L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A.L., Gill, M., Glahn, D.C., Hagg, S., Hansell, N.K., Hariri, A.R., Ikram, M.K., Jukema, J.W., Vuoksimaa, E., Keller, M.C., Kremen, W.S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N.L., Pendleton, N., Porteous, D.J., Raikkonen, K., Raitakari, O.T., Ramirez, A., Reinvang, I., Rudan, I., Dan, R., Schmidt, R., Schmidt, H., Schofield, P.W., Schofield, P.R., Starr, J.M., Steen, V.M., Trollor, J.N., Turner, S.T., Van Duijn, C.M., Villringer, A., Weinberger, D.R., Weir, D.R., Wilson, J.F., Malhotra, A., McIntosh, A.M., Gale, C.R., Seshadri, S., Mosley, T.H., Jr., Bressler, J., Lencz, T., and Deary, I.J. (2019). Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nat Commun 10, 2068. 10.1038/s41467-019-10160-w.
• De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM (2019). L1 drives IFN in senescent cells and promotes age-associated inflammation. Nature. 2019 Feb;566(7742):73-78. doi: 10.1038/s41586-018-0784-9
• Deelen, J., Evans, D.S., Arking, D.E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M.K., Biggs, M.L., van der Spek, A., Atzmon, G., Ware, E.B., Sarnowski, C., Smith, A.V., Seppala, I., Cordell, H.J., Dose, J., Amin, N., Arnold, A.M., Ayers, K.L., Barzilai, N., Becker, E.J., Beekman, M., Blanche, H., Christensen, K., Christiansen, L., Collerton, J.C., Cubaynes, S., Cummings, S.R., Davies, K., Debrabant, B., Deleuze, J.F., Duncan, R., Faul, J.D., Franceschi, C., Galan, P., Gudnason, V., Harris, T.B., Huisman, M., Hurme, M.A., Jagger, C., Jansen, I., Jylha, M., Kahonen, M., Karasik, D., Kardia, S.L.R., Kingston, A., Kirkwood, T.B.L., Launer, L.J., Lehtimaki, T., Lieb, W., Lyytikainen, L.P., Martin-Ruiz, C., Min, J., Nebel, A., Newman, A.B., Nie, C., Nohr, E.A., Orwoll, E.S., Perls, T.T., Province, M.A., Psaty, B.M., Raitakari, O.T., Reinders, M.J.T., Robine, J.M., Rotter, J.I., Sebastiani, P., Smith, J., Sorensen, T.I.A., Taylor, K.D., Uitterlinden, A.G., van der Flier, W., van der Lee, S.J., van Duijn, C.M., van Heemst, D., Vaupel, J.W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D.P., Lunetta, K.L., Slagboom, P.E., and Murabito, J.M. (2019). A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun 10, 3669. 10.1038/s41467-019-11558-2.
• Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmuller, G., Boyd, A., Zierer, J., van den Akker, E.B., Ala-Korpela, M., Amin, N., Demirkan, A., Ghanbari, M., van Heemst, D., Ikram, M.A., van Klinken, J.B., Mooijaart, S.P., Peters, A., Salomaa, V., Sattar, N., Spector, T.D., Tiemeier, H., Verhoeven, A., Waldenberger, M., Wurtz, P., Davey Smith, G., Metspalu, A., Perola, M., Menni, C., Geleijnse, J.M., Drenos, F., Beekman, M., Jukema, J.W., van Duijn, C.M., and Slagboom, P.E. (2019). A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals. Nat Commun 10, 3346. 10.1038/s41467-019-11311-9.
• Meessen JMTA, Fiocco M, Leichtenberg CS, Vliet Vlieland TPM, Slagboom PE, Nelissen RGHH (2019). Frailty Questionnaire Is Not a Strong Prognostic Factor for Functional Outcomes in Hip or Knee Arthroplasty Patients. Geriatr Orthop Surg Rehabil. 2019 Feb 4;10:2151459318808164. doi: 10.1177/2151459318808164 
• van den Berg, N, Rodríguez-Girondo M, van Dijk IK, Mourits RJ, Mandemakers K, Janssens AAPO, Beekman M, Smith KR, Slagboom PE (2019). Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait. Nat Commun. 2019 Jan 7;10(1):35. doi: 10.1038/s41467-018-07925-0
• van der Lee, S.J., Conway, O.J., Jansen, I., Carrasquillo, M.M., Kleineidam, L., van den Akker, E., Hernandez, I., van Eijk, K.R., Stringa, N., Chen, J.A., Zettergren, A., Andlauer, T.F.M., Diez-Fairen, M., Simon-Sanchez, J., Lleo, A., Zetterberg, H., Nygaard, M., Blauwendraat, C., Savage, J.E., Mengel-From, J., Moreno-Grau, S., Wagner, M., Fortea, J., Keogh, M.J., Blennow, K., Skoog, I., Friese, M.A., Pletnikova, O., Zulaica, M., Lage, C., de Rojas, I., Riedel-Heller, S., Illan-Gala, I., Wei, W., Jeune, B., Orellana, A., Then Bergh, F., Wang, X., Hulsman, M., Beker, N., Tesi, N., Morris, C.M., Indakoetxea, B., Collij, L.E., Scherer, M., Morenas-Rodriguez, E., Ironside, J.W., van Berckel, B.N.M., Alcolea, D., Wiendl, H., Strickland, S.L., Pastor, P., Rodriguez Rodriguez, E., Desgesco, E., Eadb, Ifgc, I., Ipdgc, RiMod, F.T.D., Netherlands Brain, B., Boeve, B.F., Petersen, R.C., Ferman, T.J., van Gerpen, J.A., Reinders, M.J.T., Uitti, R.J., Tarraga, L., Maier, W., Dols-Icardo, O., Kawalia, A., Dalmasso, M.C., Boada, M., Zettl, U.K., van Schoor, N.M., Beekman, M., Allen, M., Masliah, E., de Munain, A.L., Pantelyat, A., Wszolek, Z.K., Ross, O.A., Dickson, D.W., Graff-Radford, N.R., Knopman, D., Rademakers, R., Lemstra, A.W., Pijnenburg, Y.A.L., Scheltens, P., Gasser, T., Chinnery, P.F., Hemmer, B., Huisman, M.A., Troncoso, J., Moreno, F., Nohr, E.A., Sorensen, T.I.A., Heutink, P., Sanchez-Juan, P., Posthuma, D., Group, G.S., Clarimon, J., Christensen, K., Ertekin-Taner, N., Scholz, S.W., Ramirez, A., Ruiz, A., Slagboom, E., van der Flier, W.M., and Holstege, H. (2019). A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol 138, 237-250. 10.1007/s00401-019-02026-8.
• Victorelli, S., Lagnado, A., Halim, J., Moore, W., Talbot, D., Barrett, K., Chapman, J., Birch, J., Ogrodnik, M., Meves, A., Pawlikowski, J.S., Jurk, D., Adams, P.D., van Heemst, D., Beekman, M., Slagboom, P.E., Gunn, D.A., and Passos, J.F. (2019). Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction. EMBO J38, e101982. 10.15252/embj.2019101982.

Sophie Steculorum

• Steculorum, S. (2019). Deciphering the neuronal control of systemic insulin sensitivity. Chem Senses44, E11-E12.

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Philipp Steven  

• Gehlsen, U., Faust, C., Hess, D., Siebelmann, S.E., Stern, M.E., Holtick, U., Scheid, C., and Steven, P. (2019). Are Adverse Environmental Conditions during Allogeneic Hematopoietic Stem Cell Transplantation a Risk Factor for Ocular Graft-versus-Host Disease? Invest Ophth Vis Sci 60.
• Osae EA, Steven P, Redfern R, Hanlon S, Smith CW, Rumbaut RE, Burns AR (2019). Dyslipidemia and Meibomian Gland Dysfunction: Utility of Lipidomics and Experimental Prospects with a Diet-Induced Obesity Mouse Model. Int J Mol Sci. 2019 Jul 17;20(14). pii: E3505. doi: 10.3390/ijms20143505. PubMed PMID: 31319467;PubMed Central PMCID: PMC6678820 
• Steven, P., Hess, D., Jens, H., Dautzenberg, F.M., Stern, M.E., and Gehlsen, U. (2019). Application of a Cannabinoid-Receptor Agonist in a Mouse Model of Desiccating Stress. Invest Ophth Vis Sci 60.
• Wirta DL, Torkildsen GL, Moreira HR, Lonsdale JD, Ciolino JB, Jentsch G, Beckert M, Ousler GW, Steven P, Krösser S (2019). A Clinical Phase II Study to Assess Efficacy, Safety, and Tolerability of Waterfree Cyclosporine Formulation for Treatment of Dry Eye Disease. Ophthalmology. 2019 Jun;126(6):792-800. doi: 10.1016/j.ophtha.2019.01.024. Epub 2019 Jan 28. PubMed PMID: 30703441

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Peter Tessarz

• Mylonas C, Tessarz P (2019). NET-prism enables RNA polymerase-dedicated transcriptional interrogation at nucleotide resolution. RNA Biol. 2019 Sep;16(9):1156-1165. doi: 10.1080/15476286.2019.1621625. Epub 2019 Jun 3
• Nikopoulou C,Parekh S, Tessarz P (2019). Ageing and sources of transcriptional heterogeneity. Biol Chem. 400(7); 867-878   

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Marc Tittgemeyer

• Baldermann JC, Melzer C, Zapf A, Kohl S, Timmermann L, Tittgemeyer M, Huys D, Visser-Vandewalle V, Kühn AA, Horn A and Kuhn J (2019). Connectivity profile predictive of effective deep brain stimulation in obsessive compulsive disorder. Biol Psychiatry. 2019 May 1;85(9):735-743. doi: 10.1016/j.biopsych.2018.12.019. Epub 2019 Jan 9
• Edwin Thanarajah S, Backes H, DiFeliceantonio A, Albus K, Cremer AL, Hanssen R, Lippert RN, Cornely OA, Small DM, Bruening JC, Tittgemeyer M (2019) Food intake recruits orosensory and post-ingestive dopaminergic circuits to affect eating desire in humans. Cell Metabolism 2019 Mar 5;29(3):695-706.e4. doi: 10.1016/j.cmet.2018.12.006. Epub 2018 Dec 27   
• Edwin Thanarajah S, Hoffstall V, Rigoux L, Hanssen R, Brüning JC, Tittgemeyer M (2019). The role of insulin sensitivity and intranasally applied insulin on olfactory perception. Sci Rep. 2019 May 10;9(1):7222. doi: 10.1038/s41598-019-43693-7
• Edwin Thanarajah S, Iglesias S, Kuzmanovic B, Rigoux L, Stephan KE. Brüning JC, Tittgemeyer M (2019). Modulation of midbrain neurocircuitry by intranasal insulin. Neuroimage. 2019 Jul 1;194:120-127. doi: 10.1016/j.neuroimage.2019.03.050. Epub 2019 Mar 23  
• Edwin Thanarajah S, Tittgemeyer M (2019). Food reward and gut-brain signaling. Neuroforum. doi: https://doi.org/10.1515/nf-2019-0020
• Glaab E, Trezzi JP, Greuel A, Jaeger C, Hodak Z, Drzezga A, Timmermann L, Tittgemeyer M, Diederich NJ, Eggers C (2019). Integrative analysis of blood metabolomics and PET brain neuroimaging data for Parkinson’s disease. Neurobiol Dis. 2019 Apr;124:555-562. doi: 10.1016/j.nbd.2019.01.003. Epub 2019 Jan 
• Gliem C, Minnerop M, Roeske S, Gärtner H, Schoene-Bake JC, Adler S, Witt JA, Hoffstaedter F, Schneider-Gold C, Betz RC, Helmstaedter C, Tittgemeyer M, Weber B, Kornblum C (2019). Tracking the brain in myotonic dystrophies: A 5-year longitudinal follow-up study. PLoS ONE. 2019 Mar 7;14(3):e0213381. doi: 10.1371/journal.pone.0213381. eCollection 2019  
• Hammes J, Theis H, Giehl K, Hoenig MC, Greuel A, Tittgemeyer M, Timmermann L, Fink GR, Drzezga A, Eggers C, van Eimeren T (2019). Dopamine metabolism of the nucleus accumbens and fronto-striatal connectivity modulate impulse control. Brain. 2019 Mar 1;142(3):733-743. doi: 10.1093/brain/awz007
• Isaacs BR, Trutti AC, Pelzer EA, Tittgemeyer M, Temel Y, Forstmann BU, Keuken MC (2019). Cortico-basal white matter alterations occurring in Parkinson's disease. PLoS One. 2019 Aug 19;14(8):e0214343. doi: 10.1371/journal.pone.0214343. eCollection 2019  
• Kaniusas E, Kampusch S, Tittgemeyer M, Panetsos F, Gines RF, Papa M, Kiss A, Podesser B, Cassara AM, Tanghe E, Samoudi AM, Tamaud T, Joseph W, Marozas V, Lukosevicius A, Istuk N, Lechner S, Klonowski W, Varoneckas G, Szeles JC, Sarolic A (2019).  Current Directions in the Auricular Vagus Nerve Stimulation I - A Physiological Perspective. Front Neurosci. 2019; 13: 854. Published online 2019 Aug 9. doi: 10.3389/fnins.2019.00854  
• Kaniusas E, Kampusch S, Tittgemeyer M, Panetsos F, Gines RF, Papa M, Kiss A, Podesser B, Cassara AM, Tanghe E, Samoudi AM, Tamaud T, Joseph W, Marozas V, Lukosevicius A, Istuk N, Lechner S, Klonowski W, Varoneckas G, Szeles JC, Sarolic A (2019). Current Directions in the Auricular Vagus Nerve Stimulation II – An Engineering Perspective. Front Neurosci. 2019; 13: 772. Published online 2019 Jul 24. doi: 10.3389/fnins.2019.00772  
• Lippert RN, Cremer AL, Edwin Thanarajah S, Korn C, Jajans-Price T, Burgeno LM, Tittgemeyer M, Bruening JC, Walton ME, Backes H (2019). Time-dependent assessment of stimulus-evoked regional dopamine release. Nat Commun. 2019 Jan 18;10(1):336. doi: 10.1038/s41467-018-08143-4  
• Mosley P, Paliwal S, Robinson K, Coyne T, Silburn P, Stephan KE, Tittgemeyer M, Breakspeare M (2019). The Structural Connectivity of Discrete Networks Underlies Impulsivity and Gambling in Parkinson’s. Brain. 2019 Dec 1;142(12):3917-3935. doi: 10.1093/brain/awz327  
• Nettersheim FS, Loehrer PA, Weber I, Jung F, Dembek TA, Pelzer EA, Dafsari HS, Huber CA, Tittgemeyer M, Timmermann L (2019). Dopamine substitution alters effective connectivity of cortical prefrontal, premotor, and motor regions during complex bimanual finger movements in Parkinson's disease. Neuroimage. 2019 Apr 15;190:118-132. doi: 10.1016/j.neuroimage.2018.04.030. Epub 2018 Apr 23       
• Pelzer EA, Melzer C, Schönberger A, Hess M, Timmermann L, Eggers C, Tittgemeyer M (2019). Axonal degeneration in Parkinson's disease - Basal ganglia circuitry and D2 receptor availability. Neuroimage Clin.2019;23:101906. doi: 10.1016/j.nicl.2019.101906. 23, 101906 
• Thanarajah, S.E., Backes, H., DiFeliceantonio, A.G., Albus, K., Cremer, A.L., Hanssen, R., Lippert, R.N., Cornely, O.A., Small, D.M., Bruning, J.C., and Tittgemeyer, M. (2019). Food Intake Recruits Orosensory and Post-ingestive Dopaminergic Circuits to Affect Eating Desire in Humans. Cell Metab 29, 695-706 e694. 10.1016/j.cmet.2018.12.006.
• Thanarajah, S.E., Hoffstall, V., Rigoux, L., Hanssen, R., Brüning, J.C., and Tittgemeyer, M. (2019). The role of insulin sensitivity and intranasally applied insulin on olfactory perception. Sci Rep-Uk 9. ARTN 7222. 10.1038/s41598-019-43693-7.
• Thanarajah, S.E., Iglesias, S., Kuzmanovic, B., Rigoux, L., Stephan, K.E., Brüning, J.C., and Tittgemeyer, M.(2019). Modulation of midbrain neurocircuitry by intranasal insulin. Neuroimage 194, 120-127. 10.1016/j.neuroimage.2019.03.050.

Achim Tresch

• Buch, T., Moos, K., Ferreira, F.M., Fröhlic, H., Gebhard, C., and Tresch, A. (2019). Benefits of a factorial design focusing on inclusion of female and male animals in one experiment. J Mol Med (Berl).97, 871-877. 10.1007/s00109-019-01774-0.
• Failmezger, H., Dursun, E., Dümcke, S., Endele, M., Poron, D., Schroeder, T., Krug, A., and Tresch, A. (2019). Clustering of samples with a tree-shaped dependence structure, with an application to microscopic time lapse imaging. Bioinformatics35, 2291-2299. 10.1093/bioinformatics/bty939.

Aleksandra Trifunovic

• Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling JE, Dodzian J, Lagerborg KA, Vargas NE, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano DR, Kurian L (2019). Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep. 2019 Apr;20(4). pii: e47407. doi: 10.15252/embr.201847407. Epub 2019 Mar 18  
• Herholz M, Cepeda E, Baumann L, Kukat A, Hermeling J, Maciej S, Szczepanowska K, Pavlenko V, Frommolt P, Trifunovic A (2019). KLF-1 orchestrates a xenobiotic detoxification program essential for longevity of mitochondrial mutants. Nat Commun. 2019 Jul 25;10(1):3323. doi: 10.1038/s41467-019-11275-w. PMID:31346165  
• Lee HJ, Noormohammadi A, Koyuncu S, Calculli G, Simic MS, Herholz M, Trifunovic A, Vilchez D (2019). Prostaglandin signals from adult germ stem cells delay somatic aging of Caenorhabditis elegans. Nat Metab. 2019 Aug;1(8):790-810. doi: 10.1038/s42255-019-0097-9. Epub 2019 Aug 19. PMID:31485561

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Mirka Uhlirova

• Cosolo A, Jaiswal J, Csordás G, Grass I, Uhlirova M, Classen A (2019). JNK-dependent cell 1 cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress.ELife. 8:e41036. DOI: 10.7554/eLife.41036
• Mundorf J, Donohoe CD, McClure CD, Southall TD, Uhlirova M (2019). Ets21c governs tissue renewal, stress tolerance, and aging in the Drosophila intestine. Cell Rep. 27, 3019-3033.e5

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Dario Valenzano

• Ahuja G, Bartsch D, Yao W, Geissen S, Frank S, Aguirre A, Russ N, Messling JE, Dodzian J, Lagerborg KA, Vargas NE, Muck JS, Brodesser S, Baldus S, Sachinidis A, Hescheler J, Dieterich C, Trifunovic A, Papantonis A, Petrascheck M, Klinke A, Jain M, Valenzano DR, Kurian L (2019). Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep. 2019 Apr;20(4). pii: e47407. doi: 10.15252/embr.201847407. Epub 2019 Mar 18
• Aleman FDD, Valenzano DR (2019). Microbiome evolution during host aging. PLoS Pathog. 2019 Jul 25;15(7):e1007727. doi: 10.1371/journal.ppat.1007727. eCollection 2019 Jul   
• Bradshaw WJ, Šajina A, Valenzano DR (2019). AEGIS: An In Silico Tool to model Genome Evolution in Age-Structured Populations. bioRxiv. https://doi.org/10.1101/646877
• Bradshaw WJ, Valenzano DR (2019). Extreme genomic volatility characterises the evolution of the immunoglobulin heavy chain locus in teleost fishes. bioRxiv.  https://doi.org/10.1101/752063
• Cui R, Medeiros T, Willemsen D, Iasi LNM, Collier GE, Graef M, Reichard M, Valenzano DR (2019). Relaxed Selection Limits Lifespan by Increasing Mutation Load. Cell. 2019 Jul 11;178(2):385-399.e20. doi: 10.1016/j.cell.2019.06.004. Epub 2019 Jun 27
• Dolfi L, Ripa R, Antebi A, Valenzano DR, Cellerino A (2019). Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology. EvoDevo. 2019 Nov 8;10:29. doi: 10.1186/s13227-019-0142-5. eCollection 2019
• Keesey I, Grabe V, Gruber L, Koerte S, Obiero G, Bolton G, Khallaf M, Kunert G, Lavista-Llanos S, Valenzano DR, Rybak J, Barrett B, Knaden M, Hansson B (2019).Inverse resource allocation between vision and olfaction across the genus Drosophila. Nat Commun. 2019 Mar 11;10(1):1162. doi: 10.1038/s41467-019-09087-z         
• Metge F, Kim Y, Boucas J, Dieterich C, Valenzano DR (2019). Circular RNAs in the ageing African turquoise killifish. bioRxiv. https://doi.org/10.1101/699694 
• Willemsen D, Cui R, Reichard M, Valenzano DR (2019). Intra-species differences in population size shape life history and genome evolution. bioRxiv.  doi.org/10.1101/852368 

David Vilchez 

• Fatima A, Gutierrez-Garcia R, Vilchez D (2019). Induced pluripotent stem cells from Huntington's disease patients: a promising approach to define and correct disease-related alterations. Neural Regen Res. 14:769-770 
• Kumsta C, Chang JT, Lee R, Tan EP, Yang Y, Loureiro R, Choy EH, Lim SHY, Saez I, Springhorn A, Hoppe T, Vilchez D, Hansen M (2019). The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy. Nat Commun. 10: 5648
• Lee HJ, Noormohammadi A, Koyuncu S, Calculli G, Simic M, Herholz M, Trifunovic A,  Vilchez D (2019). Prostaglandin signals from adult germline stem cells delay somatic ageing of Caenorhabditis elegans.  Nat Metab. 2019 Aug;1(8):790-810. doi: 10.1038/s42255-019-0097-9. Epub 2019 Aug 19  

Silvia von Karstedt

• Heilmann T, Vondung F, Borzikowsky C, Szymczak S, Krüger S, Alkatout I, Wenners A, Bauer M, Klapper W, Röcken C, Maass N, von Karstedt S, Schem C, Trauzold A (2019). Heterogeneous intracellular TRAIL-receptor distribution predicts poor outcome in breast cancer patients. J Mol Med (Berl). 2019 Aug;97(8):1155-1167. doi:10.1007/s00109-019-01805-w. Epub 2019 Jun 10         
• Kretz AL, Trauzold A, Hillenbrand A, Knippschild U, Henne-Bruns D, von Karstedt S, Lemke J (2019). TRAILblazing Strategies for Cancer Treatment. Cancers (Basel). 2019 Mar 30;11(4). pii: E456. doi:10.3390/cancers11040456. Review.
• Lim JKM, Delaidelli A, Minaker SW, Zhang HF, Colovic M, Yang H, Negri GL, von Karstedt S, Lockwood WW, Schaffer P, Leprivier G, Sorensen PH (2019). Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9433-9442. doi:10.1073/pnas.1821323116. Epub 2019 Apr 18           
• Mert U, Adawy A, Scharff E, Teichmann P, Willms A, Haselmann V, Colmorgen C, Lemke J, von Karstedt S, Fritsch J, Trauzold A (2019). TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors. Cancers (BASEL). 2019 Aug 14;11(8). pii: E1167. doi: 10.3390/cancers11081167

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Henning Walczak

• Aalto AL, Mohan AK, Schwintzer L, Kupka S, Kietz C, Walczak H, Broemer M, Meinander A (2019). M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila. Cell Death Differ. 26, pages860–876, 2019  
• Krishna-Subramanian S, Singer S, Armaka M, Banales JM, Holzer K, Schirmacher P, Walczak H, Kollias G, Pasparakis M, Kondylis V (2019). RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ. 26(12):2710-2726, Epub 2019  
• Peltzer N, Walczak H (2019). Cell Death and Inflammation - A Vital but Dangerous Liaison. Trends Immunol.2019 May; 40(5):387-402. doi: 10.1016/j.it.2019.03.006. Epub 2019 Apr 16. Review. PMID: 31003931
• Peltzer N, Walczak H (2019). Endothelial Cell Killing by TAK1 Inhibition: A Novel Anti-angiogenic Strategy in Cancer Therapy. Dev Cell. Jan 28;48(2):127-128. doi: 10.1016/j.devcel.2019.01.011., 2019  
• Spit M, Rieser E, Walczak H (2019). Linear ubiquitination at a glance. J Cell Sci. 2019 Jan 18;132(2)  Peltzer N, Walczak H (2019). Cell Death and Inflammation - A Vital but Dangerous Liaison. Trends Immunol. 2019 May; 40(5):387-402. doi: 10.1016/j.it.2019.03.006. Epub 2019 Apr 16. Review. PMID: 31003931 

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Sara Wickström 

• Miroshnikova YA, Cohen I, Ezhkova E, Wickström SA (2019). Epigenetic gene regulation, chromatin structure and force-induced chromatin remodelling in epidermal development and homeostasis, Curr Opin Genet Dev. 2019 Apr;55:46-51. doi: 10.1016/j.gde.2019.04.014. Epub 2019 May 18   
• Miroshnikova YA, Hammesfahr T, Wickström SA (2019). Cell biology and mechanopathology of laminopathic cardiomyopathies. J Cell Biol. 218, 393-394
• Ou HL, Kim CS, Uszkoreit S, Wickström SA, Schumacher B (2019). Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells. Dev Cell. 2019 Jul 22;50(2):167-183.e8. doi: 10.1016/j.devcel.2019.06.012   
• Wickström, S.A., and Roca-Cusachs, P. (2019). Special issue on "mechanotransduction in cell fate determination" - From molecular switches to organ-level regulation. Exp Cell Res 382. ARTN 111452. 10.1016/j.yexcr.2019.05.033.
• Wickström, S.A., and Yang, Y.Z. (2019). Editorial overview: Cell differentiation and development - wiring principles of transcriptional states, signaling networks and cell fate trajectories. Curr Opin Cell Biol 61, Iii-Vi. 10.1016/j.ceb.2019.10.002.

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Rudolf J. Wiesner  

• Aatsinki SM, Elkhwanky MS, Kummu O, Karpale M, Buler M, Viitala P, Rinne V, Mutikainen M, Tavi P, Franko A, Wiesner RJ, Chambers KT, Finck BN, Hakkola J (2019). Fasting-induced transcription factors repress vitamin D bioactivation, a mechanism for vitamin D deficiency in diabetes. Diabetes. 68: 918-93  
• Boix, J., Nätlitz, J., Baris, O., and Wiesner, R.J. (2019). The role of HIF1a in skin: trying to preserve epidermal homeostasis during mitochondrial dysfunction. Exp Dermatol 28, E37-E37.
• Bugiardini E, Mitchell A, Dalla Rosa I, Hornig-Do HT, Pittman A, Poole O, Holton J, Shah S, Woodward C, Hargreaves I, Quinlivan R, Amunts A, Wiesner RJ, Houlden H, Holt I, Hanna M, Pitceathly R, Spinazzola A (2019). MRP25 mutations impair mitochondrial translation and cause encephalomyopathy. Hum Mol Genet. 28: 2711-2719
• Holzer T, Probst K, Etich J, Auler M, Georgieva VS, Bluhm B, Frie C, Heilig J, Niehoff A, Nüchel N, Plomann M, Seeger JM, Kashkar H, Baris OR, Wiesner RJ, Brachvogel B (2019). ^­­­Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases. J Cell Biol. 218: 1853-1870  
• Lubomirov LT, Gagov H, Schroeter MM, Wiesner RJ, Franko A (2019). Augmented contractility of murine femoral arteries in a streptozotocin diabetes model is related to increased phosphorylation of MYPT1. Physiol Reports. 7:e13975  
• Naetlitz, J., Boix, J., Weiland, D., Eming, S.A., and Wiesner, R.J. (2019). Mitochondrial DNA depletion leads to impaired proliferation, migration and contractile performance of dermal fibroblasts. Exp Dermatol 28, E15-E16.
• Pla-Martin D, Wiesner RJ (2019). Reshaping membranes to build mitochondrial DNA. PLOS Genetics. 15: e1008140  
• Urbanczyk, S., Baris, O., Reimer, D., Steinmetz, T., Mougiakakos, D., Wiesner, R., and Mielenz, D. (2019). Mitochondrial metabolism influences plasma cell differentiation. Eur J Immunol 49, 189-190.
• Wiesner, R.J. (2019). Johann Caspar Ruegg (1930-2018) Obituary. J Muscle Res Cell M 40, 279-289. 10.1007/s10974-019-09522-0.

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Andreas Wodarz

• Tiwari MD, Zeitler DM, Meister G, Wodarz A (2019). Molecular profiling of stem cell-like female germ line cells in Drosophila delineates networks important for stemness and differentiation.Biol Open. 2019 Nov 12;8(11). pii: bio046789. doi: 10.1242/bio.046789

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Thomas Wunderlich

• Blakemore, S.J., Kohlhaas, V., Al-Maarri, M., Knittel, G., Reinhardt, C., Hallek, M., Peifer, M., Wunderlich, T., and Pallasch, C. (2019). Pan-omics assessment of constitutive AKT-activation in the Eμ-TCL1 CLL-like mouse model. Oncol Res Treat 42, 18-18.
• Lahmann, I., Bröhl, D., Zyrianova, T., Isomura, A., Czajkowski, M.T., Kapoor, V., Griger, J., Ruffault, P.L., Mademtzoglou, D., Zammit, P.S., Wunderlich, T., Spuler, S., Kühn, R., Preibisch, S., Wolf, J., Kageyama, R., and Birchmeier, C. (2019). Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells. Gene Dev 33, 524-535. 10.1101/gad.322818.118.
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